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https://www.readbyqxmd.com/read/29916299/characteristics-of-uterine-rupture-after-laparoscopic-surgery-of-the-uterus-clinical-analysis-of-10-cases-and-literature-review
#1
Xiaoyi Wu, Wei Jiang, Huan Xu, Xuping Ye, Congjian Xu
Objective An increasing trend of uterine rupture (UR) after laparoscopic surgery of the uterus (LSU) has been observed. Although the overall incidence is extremely low, UR may have catastrophic outcomes. Therefore, investigation of its potential risk factors is important. Methods We retrospectively reviewed the medical data of 10 women who developed UR after LSU performed at our hospital from October 2003 to October 2016 and conducted a literature review. Results All cases of UR occurred during the third trimester of pregnancy...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29916110/intravenous-carbetocin-versus-intravenous-oxytocin-for-preventing-atonic-postpartum-hemorrhage-after-normal-vaginal-delivery-in-high-risk-singleton-pregnancies-a-triple-blind-randomized-controlled-trial
#2
Paweena Amornpetchakul, Tripop Lertbunnaphong, Dittakarn Boriboonhiransarn, Jarunee Leetheeragul, Ratree Sirisomboon, Ratchada Jiraprasertwong
PURPOSE: To compare the effectiveness of intravenous carbetocin to that of intravenous oxytocin for prevention of atonic postpartum hemorrhage (PPH) after vaginal delivery in high-risk singleton pregnancies. METHODS: This triple-blind randomized controlled trial included singleton pregnant women who delivered at Siriraj Hospital between August 2016 and January 2017 and who were 20 years or older, had a gestational age of at least 34 weeks, had a vaginal delivery, and had at least one risk factor for atonic postpartum hemorrhage...
June 18, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29915921/pharmacokinetics-of-hiv-integrase-inhibitors-during-pregnancy-mechanisms-clinical-implications-and-knowledge-gaps
#3
REVIEW
Ruben van der Galiën, Rob Ter Heine, Rick Greupink, Stein J Schalkwijk, Antonius E van Herwaarden, Angela Colbers, David M Burger
Prevention of mother-to-child transmission of HIV and optimal maternal treatment are the most important goals of antiretroviral therapy in pregnant women with HIV. These goals may be at risk due to possible reduced exposure during pregnancy caused by physiological changes. Limited information is available on the impact of these physiological changes. This is especially true for HIV-integrase inhibitors, a relatively new class of drugs, recommended first-line agents and hence used by a large proportion of HIV-infected patients...
June 19, 2018: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/29915851/genotype-patterns-and-prevalence-of-human-papilloma-virus-in-non-vaccinated-women-in-zunyi-china
#4
Yu Zhao, Kaifeng Wu, Huabo Tong, Yan Liu, He Zha, Huan Yue, Jingzhi Zhang, Xiaoyun Liu
OBJECTIVES: To determine the patterns and prevalence of human papilloma virus (HPV) genotypes in people who are not vaccinated with HPV vaccines in Zunyi. METHODS: We retrospectively collected all HPV testing results in 3,393 patients at the Third Affiliated Hospital in Zunyi Medical University, Zunyi, China between January 2014 and December 2016. The prevalence of HPV genotypes based on different stages of cervical lesions and age groups was analyzed. The clinical data of 347 HPV-positive inpatients were also retrospectively collected, and difference in the age at first sexual encounter, smoking, pregnancy, and abortion status were compared...
June 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29915441/dengue-fever-during-pregnancy
#5
Trinh Tien Dat, Tomomi Kotani, Eiko Yamamoto, Kiyosumi Shibata, Yoshinori Moriyama, Hiroyuki Tsuda, Mamoru Yamashita, Hiroaki Kajiyama, Dien Duc Thien Minh, Le Quang Thanh, Fumitaka Kikkawa
Dengue fever during pregnancy is an expanding issue in Southeast Asia; however, the knowledge of adverse effects on mothers and neonates remains limited. Therefore, we aimed to determine the impact of dengue fever. The clinical information of 20 patients of dengue fever during pregnancy in Vietnam from January 1, 2015 to December 31, 2015 was collected and their outcomes were retrospectively investigated. A total of 18 patients (90%) presented with positivity of nonstructural protein 1, and a primary infection...
May 2018: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29915020/risk-of-preeclampsia-and-pregnancy-complications-in-women-with-a-history-of-acute-kidney-injury
#6
Jessica Sheehan Tangren, Wan Ahmad Hafiz Wan Md Adnan, Camille E Powe, Jeffrey Ecker, Kate Bramham, Michelle A Hladunewich, Elizabeth Ankers, S Ananth Karumanchi, Ravi Thadhani
An episode of clinically recovered acute kidney injury (r-AKI) has been identified as a risk factor for future hypertension and cardiovascular disease. Our objective was to assess whether r-AKI was associated with future preeclampsia and other adverse pregnancy outcomes and to identify whether severity of AKI or time interval between AKI and pregnancy was associated with pregnancy complications. We conducted a retrospective cohort study of women who delivered infants between 1998 and 2016 at Massachusetts General Hospital...
June 18, 2018: Hypertension
https://www.readbyqxmd.com/read/29914780/understanding-the-experiences-of-east-african-immigrant-women-with-gestational-diabetes-mellitus
#7
Fartoon M Siad, Xiao Yang Fang, Maria J Santana, Sonia Butalia, Marilynne A Hebert, Doreen M Rabi
OBJECTIVES: East African (EA) women are a subpopulation who are at very high risk for gestational diabetes (GDM) and poor obstetric outcomes, but little is known about the care experiences of this understudied group. The objective of this study was to document the impact of a diagnosis of GDM and the perceptions of diabetes care among EA immigrant women. METHODS: Semistructured in-depth interviews were conducted with 10 EA immigrant women diagnosed with GDM in Calgary; they were recruited from community and tertiary care settings...
February 2, 2018: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29914699/-occupational-risk-during-pregnancy-and-sick-leave-in-a-cohort-of-workers-from-parc-de-salut-mar-barcelona-spain
#8
Rocío Villar, Fernando G Benavides, Laura Serra, Consol Serra
OBJECTIVE: To study the use of the Pregnancy occupational risk benefit (PORB) and non-work related sickness absence (NWSA) in a cohort of pregnant workers of Parc de Salut Mar, Barcelona (Spain). METHOD: Retrospective cohort study of 428 pregnant workers between 2010 and 2014, who were followed-up until delivery. Absences from work, both PORB and NWSA were recorded until the beginning of their maternity leave. The sequence analysis identifies four trajectories, which are described according to workers demographic and job characteristics...
June 15, 2018: Gaceta Sanitaria
https://www.readbyqxmd.com/read/29914628/fetal-one-carbon-nutrient-concentrations-may-be-affected-by-gestational-diabetes
#9
Eran Barzilay, Ashley Moon, Lesley Plumptre, Shannon P Masih, Kyoung-Jin Sohn, Carly E Visentin, Anna Ly, Olga Malysheva, Ruth Croxford, Marie A Caudill, Deborah L O'Connor, Young-In Kim, Howard Berger
Both insufficiency and excess of one-carbon nutrients (folate, choline, vitamins B6 and B12) during pregnancy have been associated with gestational diabetes mellitus (GDM). However, the precise nature of this association has not been clearly established. We hypothesized that GDM may affect one-carbon nutrients concentrations in the fetus, thus possibly participating in epigenetic programing of the offspring. Maternal blood was collected at recruitment (12-16 weeks). At delivery (28-42 weeks), both maternal and cord blood were collected...
July 2018: Nutrition Research
https://www.readbyqxmd.com/read/29914601/burden-of-tuberculosis-in-hiv-positive-pregnant-women-in-cape-town-south-africa
#10
J Odayar, M X Rangaka, A Zerbe, G Petro, J A McIntyre, T K Phillips, E J Abrams, L Myer
BACKGROUND: The burden of active tuberculosis (TB) in pregnancy compared with preconception and postpartum is unclear, particularly with universal antiretroviral therapy (ART) initiation in pregnancy. METHODS: We retrospectively compared active TB incidence in the 18 months preconception, during pregnancy and up to 6 months postpartum in human immunodeficiency virus (HIV) positive women attending antenatal care at a primary health care facility in Cape Town from 2013 to 2014...
July 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29914496/outcomes-of-neonates-born-following-transfers-of-frozen-thawed-cleavage-stage-embryos-with-blastomere-loss-a-prospective-multicenter-cohort-study
#11
Yan-Ting Wu, Cheng Li, Yi-Min Zhu, Shu-Hua Zou, Qiong-Fang Wu, Li-Ping Wang, Yan Wu, Rong Yin, Chao-Yi Shi, Jing Lin, Zi-Ru Jiang, Yi-Jing Xu, Yun-Fei Su, Jian Zhang, Jian-Zhong Sheng, William D Fraser, Zhi-Wei Liu, He-Feng Huang
BACKGROUND: Despite limited information on neonatal safety, the transfer of frozen-thawed cleavage-stage embryos with blastomere loss is common in women undergoing in vitro fertilization. We aimed to evaluate the pregnancy outcomes and safety of frozen-thawed cleavage-stage embryos with blastomere loss. METHODS: This prospective, multicenter, cohort study included all frozen-thawed cleavage-stage embryo transfer (FET) cycles between 2002 and 2012. Pregnancy outcomes and subsequent neonatal outcomes were compared between FET cycles with intact embryos and those with blastomere loss...
June 19, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29914422/sexual-health-in-the-french-military-a-multidimensional-and-gendered-perspective
#12
Sandrine Duron, Aline Bohet, Henri Panjo, Nathalie Bajos, René Migliani, Catherine Marimoutou, Yann Le Strat, Jean Baptiste Meynard, Caroline Moreau
BACKGROUND: Sexual health in the military comprises a range of concerns including sexually transmitted infections (STI), unintended pregnancy, sexual violence and sexual dysfunction. This study aims to estimate the prevalence of sexual health concerns by gender in the French military and compare these prevalences to estimates in the general population. METHODS: COSEMIL, the first sexual health survey in the French military comprises a probability sample of 1500 military personnel...
June 18, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29914280/primipaternity-and-birth-interval-independent-risk-factors-for-preeclampsia
#13
A Hercus, S Leemaqz, G Dekker
BACKGROUND: The exact cause of preeclampsia remains unknown. The past decade has seen an ongoing debate on the relative importance of primipaternity versus prolonged birth/pregnancy interval. AIMS: The aim of the current study was to analyze these two major potential risk factors in a high risk population in the Northern suburbs of Adelaide; a socioeconomically disadvantaged area characterized by instable relationships and overall poor health and lifestyle. METHODS: A retrospective cohort study was performed on all multigravid women birthing at the Lyell McEwin Hospital, Adelaide, from July 2011 to August 2012; 2003 patients were included in this analysis...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29914277/the-fetal-fibronectin-test-25-years-after-its-development-what-is-the-evidence-regarding-its-clinical-utility-a-systematic-review-and-meta-analysis
#14
Gilles Faron, Lisa Balepa, José Parra, Jean-François Fils, Leonardo Gucciardo
BACKGROUND: The identification of women at risk for preterm birth should allow interventions which could improve neonatal outcome. Fetal fibronectin, a glycoprotein which acts normally as glue between decidua and amniotic membranes could be a good marker of impending labour when its concentration in cervicovaginal secretions between 22 and 36 weeks of gestation is ≥ 50 ng/mL. Many authors worldwide have tested this marker with many different methodologies and clinical settings, but conclusions about its clinical use are mixed...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29913174/low-dose-aspirin-is-associated-with-reduced-spontaneous-preterm-birth-in-nulliparous-women
#15
Maria Andrikopoulou, Stephanie E Purisch, Roxane Handal-Orefice, Cynthia Gyamfi-Bannerman
BACKGROUND: Preterm birth (PTB) is one of the leading causes of perinatal morbidity and mortality. Clinical data suggests that low dose aspirin may decrease the rate of overall PTB, but investigators have speculated that this is likely due to a decrease in medically indicated PTB through its effect on the incidence of preeclampsia and other placental disease. We hypothesized that low dose aspirin may also impact the mechanism of spontaneous preterm labor. OBJECTIVE: Our objective was to determine whether low dose aspirin reduces the rate of spontaneous PTB in nulliparous women without medical co-morbidities...
June 15, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29913173/diagnostic-accuracy-of-4-th-generation-architect-hiv-ag-ab-combo-assay-and-utility-of-signal-to-cutoff-ratio-to-predict-false-positive-hiv-tests-in-pregnancy
#16
Emily H Adhikari, Devin Macias, Donna Gaffney, Sarah White, Vanessa L Rogers, Donald D McIntire, Scott W Roberts
BACKGROUND: False positive HIV screening tests in pregnancy may lead to unnecessary interventions in labor. In 2014, the Centers for Disease Control and Prevention released a new algorithm for HIV diagnosis using a 4th generation screening test, which detects antibodies to HIV as well as p24 antigen and has a shorter window period compared with prior generations. A reactive screen requires a differentiation assay, and supplemental qualitative RNA testing is necessary for nonreactive differentiation assay...
June 15, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29913015/comparison-of-safety-and-efficacy-of-methadone-vs-morphine-for-treatment-of-neonatal-abstinence-syndrome-a-randomized-clinical-trial
#17
Jonathan M Davis, Jeffrey Shenberger, Norma Terrin, Janis L Breeze, Mark Hudak, Elisha M Wachman, Peter Marro, Erica L Oliveira, Karen Harvey-Wilkes, Adam Czynski, Barbara Engelhardt, Karen D'Apolito, Debra Bogen, Barry Lester
Importance: Although opioids are used to treat neonatal abstinence syndrome (NAS), the best pharmacologic treatment has not been established. Objective: To compare the safety and efficacy of methadone and morphine in NAS. Design, Setting, and Participants: In this randomized, double-blind, intention-to-treat trial, term infants from 8 US newborn units whose mothers received buprenorphine, methadone, or opioids for pain control during pregnancy were eligible...
June 18, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29912960/understanding-women-s-uptake-and-adherence-in-option-b-for-prevention-of-mother-to-child-hiv-transmission-in-papua-indonesia-a-qualitative-study
#18
Christina Lumbantoruan, Michelle Kermode, Aloisius Giyai, Agnes Ang, Margaret Kelaher
BACKGROUND: Despite a more proactive approach to reducing new HIV infections in infants through lifelong treatment (Option B+ policy) for infected pregnant women, prevention of mother-to-child transmission of HIV (PMTCT) has not been fully effective in Papua, Indonesia. Mother-to-child transmission (MTCT) is the second greatest risk factor for HIV infection in the community, and an elimination target of <1% MTCT has not yet been achieved. The purpose of this study was to improve understanding of the implementation of Option B+ for PMTCT in Papua through investigation of facilitators and barriers to women's uptake and adherence to antiretroviral therapy (ART) in the program...
2018: PloS One
https://www.readbyqxmd.com/read/29912235/-peripartum-cardiomyopathy-a-little-known-disease
#19
Angela Beatrice Scardovi, Renata De Maria
Peripartum cardiomyopathy (PPCM) is a relatively rare cardiac disease that manifests itself in the final stage of pregnancy and in the first months after delivery in women with no previous history of cardiovascular disease. The incidence of PPCM varies widely across geographic areas and seems to be on the rise as a result of increased awareness and socioeconomic changes. PPCM recognizes a still partially undefined multifactorial etiology. Various pathogenetic hypotheses have been proposed, that range from autoimmune mechanisms to myocarditis to the hormonal hypothesis for aberrant, antiangiogenic and cardiotoxic prolactin (PRL) production, apoptosis, prolonged exposure to tocolytic drugs, malnutrition and genetic predisposition...
April 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29912017/hypertensive-disorders-of-pregnancy-and-genital-anomalies-in-boys-a-danish-nationwide-cohort-study
#20
Linn Håkonsen Arendt, Tine Brink Henriksen, Morten Søndergaard Lindhard, Erik T Parner, Jørn Olsen, Cecilia Høst Ramlau-Hansen
BACKGROUND: Although congenital abnormalities in the male reproductive tract are common, their causes remain poorly understood. We studied associations between hypertensive disorders of pregnancy (pre-gestational hypertension, gestational hypertension, and preeclampsia) and the genital anomalies, cryptorchidism (undescended testes), and hypospadias (ventrally displaced urethral meatus). METHODS: We established a population of 1,073,026 Danish boys born alive between 1 January 1978 and 31 December 2012...
June 14, 2018: Epidemiology
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