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https://www.readbyqxmd.com/read/28222581/a-comparison-of-the-physiological-demands-imposed-by-competing-in-a-half-marathon-vs-a-marathon
#1
Juan Del Coso, Juan J Salinero, Beatriz Lara, Javier Abián-Vicén, César Gallo-Salazar, Francisco Areces
BACKGROUND: While there is widespread scientific information about the physiological challenges imposed on elite endurance runners during competitions, the information regarding the amateur population is scarce. The aim of this study was to compare the physical and physiological load imposed by competing in a real half-marathon vs a marathon race. METHODS: From a larger group of participants, we selected 22 experienced runners who were matched in pairs (11 marathoners and 11 half-marathoners) for age and anthropometric data...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28207880/skeletal-muscle-metabolic-adaptations-to-endurance-exercise-training-are-attainable-in-mice-with-simvastatin-treatment
#2
William M Southern, Anna S Nichenko, Daniel D Shill, Corey C Spencer, Nathan T Jenkins, Kevin K McCully, Jarrod A Call
We tested the hypothesis that a 6-week regimen of simvastatin would attenuate skeletal muscle adaptation to low-intensity exercise. Male C57BL/6J wildtype mice were subjected to 6-weeks of voluntary wheel running or normal cage activities with or without simvastatin treatment (20 mg/kg/d, n = 7-8 per group). Adaptations in in vivo fatigue resistance were determined by a treadmill running test, and by ankle plantarflexor contractile assessment. The tibialis anterior, gastrocnemius, and plantaris muscles were evaluated for exercised-induced mitochondrial adaptations (i...
2017: PloS One
https://www.readbyqxmd.com/read/28198604/energy-requirements-of-tyre-pulling
#3
Per M Fredriksen, Asgeir Mamen
BACKGROUND: We have investigated the effect using walking poles and pulling tyres at 4 and 6 km·h-1 (1.11 and 1.67 m·s-1) speeds on oxygen uptake (V̇ O2) and heart rate. METHODS: Twelve subjects, 6 males, with a mean (SD) age of 25.2(6.9) years participated in field tests involving walking without poles, walking with poles and tyre pulling with poles. RESULTS: Increasing the load caused the largest increases in energy demand, more than 4 MET...
February 14, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28197103/increases-in-brain-1-h-mr-glutamine-and-glutamate-signals-following-acute-exhaustive-endurance-exercise-in-the-rat
#4
Maciej Świątkiewicz, Michał Fiedorowicz, Jarosław Orzeł, Marlena Wełniak-Kamińska, Piotr Bogorodzki, Józef Langfort, Paweł Grieb
Objective: Proton magnetic resonance spectroscopy ((1)H-MRS) in ultra-high magnetic field can be used for non-invasive quantitative assessment of brain glutamate (Glu) and glutamine (Gln) in vivo. Glu, the main excitatory neurotransmitter in the central nervous system, is efficiently recycled between synapses and presynaptic terminals through Glu-Gln cycle which involves glutamine synthase confined to astrocytes, and uses 60-80% of energy in the resting human and rat brain. During voluntary or involuntary exercise many brain areas are significantly activated, which certainly intensifies Glu-Gln cycle...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28195978/lack-of-influence-of-muscular-performance-parameters-on-spatio-temporal-adaptations-with-increased-running-velocity
#5
Luis E Roche-Seruendo, Felipe García-Pinillos, Joana Haicaguerre, Ana V Bataller-Cervero, Víctor M Soto-Hermoso, Pedro Á Latorre-Román
This study aimed to analyse the influence of muscular performance parameters on spatio-temporal gait characteristics during running when gradually increasing speed. 51 recreationally trained male endurance runners (age: 28 ± 8 years) voluntarily participated in this study. Subjects performed a battery of jumping tests (squat jump, countermovement jump, and 20 cm drop jump), and after that, the subjects performed an incremental running test (10 to 20 km/h) on a motorized treadmill. Spatio-temporal parameters were measured using the OptoGait system...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28193888/interleukin-37-reverses-the-metabolic-cost-of-inflammation-increases-oxidative-respiration-and-improves-exercise-tolerance
#6
Giulio Cavalli, Jamie N Justice, Kristen E Boyle, Angelo D'Alessandro, Elan Z Eisenmesser, Jonathan J Herrera, Kirk C Hansen, Travis Nemkov, Rinke Stienstra, Cecilia Garlanda, Alberto Mantovani, Douglas R Seals, Lorenzo Dagna, Leo A B Joosten, Dov B Ballak, Charles A Dinarello
IL-1 family member interleukin 37 (IL-37) has broad antiinflammatory properties and functions as a natural suppressor of innate inflammation. In this study, we demonstrate that treatment with recombinant human IL-37 reverses the decrease in exercise performance observed during systemic inflammation. This effect was associated with a decrease in the levels of plasma and muscle cytokines, comparable in extent to that obtained upon IL-1 receptor blockade. Exogenous administration of IL-37 to healthy mice, not subjected to an inflammatory challenge, also improved exercise performance by 82% compared with vehicle-treated mice (P = 0...
February 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28182775/relationship-between-anaerobic-capacity-estimated-using-a-single-effort-and-30-s-tethered-running-outcomes
#7
Alessandro Moura Zagatto, Willian Eiji Miyagi, Filipe Antônio de Barros Sousa, Claudio Alexandre Gobatto
The purpose of the current study was to investigate the relationship between alternative anaerobic capacity method (MAODALT) and a 30-s all-out tethered running test. Fourteen male recreational endurance runners underwent a graded exercise test, a supramaximal exhaustive effort and a 30-s all-out test on different days, interspaced by 48h. After verification of data normality (Shapiro-Wilk test), the Pearson's correlation test was used to verify the association between the anaerobic estimates from the MAODALT and the 30-s all-out tethered running outputs...
2017: PloS One
https://www.readbyqxmd.com/read/28181710/on-field-prediction-vs-monitoring-of-aerobic-capacity-markers-using-submaximal-lactate-and-heart-rate-measures
#8
Ibai Garcia-Tabar, Mikel Izquierdo, Esteban M Gorostiaga
This study aimed to validate the use of a single blood lactate concentration measurement taken following a 5-min running bout at 10 km·h(-1) (BLC10 ) and the speed associated with 90% of maximal heart rate (S90 ) to predict and monitor fixed blood lactate concentration (FBLC) thresholds in athletes. Three complementary studies were undertaken. Study-I: A cross-sectional study examining the associations of BLC10 and S90 with running speeds at FBLC of 3 (S3mM) and 4 mmol·L(-1) (S4mM) in 100 athletes. Study-II: A cross-validation study assessing the predictive capacity of BLC10 and S90 to estimate FBLC thresholds in real practice...
February 9, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28177747/short-term-heat-acclimation-improves-the-determinants-of-endurance-performance-and-5-000-m-running-performance-in-the-heat
#9
Carl Alexander James, Alan J Richardson, Peter W Watt, Ashley G B Willmott, Oliver R Gibson, Neil S Maxwell
This study investigated the effect of 5 days controlled hyperthermia heat acclimation (STHA) on the determinants of endurance performance and 5 km performance in runners, relative to the impairment afforded by moderate heat stress. A control group (CON), matched for total work and power output (2.7 W.kg-1), differentiated thermal and exercise contributions of STHA on exercise performance. Seventeen participants (10 STHA, 7 CON) completed graded exercise tests (GXT) in cool (13°C, 50% RH, pre training) and hot conditions (32°C, 60% RH, pre and post training), as well as 5 km time trials (TT) in the heat, pre and post training...
November 18, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28177715/gut-training-the-impact-of-two-weeks-repetitive-gut-challenge-during-exercise-on-gastrointestinal-status-glucose-availability-fuel-kinetics-and-running-performance
#10
Ricardo J S Costa, Atlanta Miall, Anthony Khoo, Christopher Rauch, Rhiannon Snipe, Vera Camões-Costa, Peter Gibson
BACKGROUND: Due to gastrointestinal tract adaptability, the study aimed to determine the impact of two weeks gut-training protocol over two weeks on gastrointestinal status, blood glucose availability, fuel kinetics, and running performance. METHODS: Endurance runners (n= 25) performed a gut-challenge trial (GC1), comprising of 2 h running exercise at 60% VO2max whilst consuming gel-discs containing 30 g carbohydrates (2:1 glucose-fructose, 10% w/v) every 20 min, and a 1 h distance test...
January 19, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28174540/the-influence-of-mid-event-deception-on-psychophysiological-status-and-pacing-can-persist-across-consecutive-disciplines-and-enhance-self-paced-multi-modal-endurance-performance
#11
Daniel Taylor, Mark F Smith
Purpose: To examine the effects of deceptively aggressive bike pacing on performance, pacing, and associated physiological and perceptual responses during simulated sprint-distance triathlon. Methods: Ten non-elite, competitive male triathletes completed three simulated sprint-distance triathlons (0.75 km swim, 500 kJ bike, 5 km run), the first of which established personal best "baseline" performance (BL). During the remaining two trials athletes maintained a cycling power output 5% greater than BL, before completing the run as quickly as possible...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28169569/physical-activity-and-motor-competence-present-a-positive-reciprocal-longitudinal-relationship-across-childhood-and-early-adolescence
#12
Rodrigo A Lima, Karin Pfeiffer, Lisbeth R Larsen, Anna Bugge, Niels C Moller, Lars B Anderson, David F Stodden
BACKGROUND: The current study evaluated the reciprocal longitudinal relationship between physical activity (PA) and motor competence (MC) and the potential mediation of cardiorespiratory endurance across seven years. METHODS: This was a seven-year longitudinal study with three measuring points (mean ages [in years] and respective sample size: 6.75 ±0.37, n=696; 9.59 ±1.07, n=617; 13.35 ±0.34, n=513) - the Copenhagen School Child Intervention Study (CoSCIS). PA was assessed using accelerometers...
February 7, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28167917/forced-running-endurance-is-influenced-by-gene-s-on-mouse-chromosome-10
#13
Mindaugas Kvedaras, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Tomas Venckunas, Arimantas Lionikas
Phenotypic diversity between laboratory mouse strains provides a model for studying the underlying genetic mechanisms. The A/J strain performs poorly in various endurance exercise models. The aim of the study was to test if endurance capacity and contractility of the fast- and slow-twitch muscles are affected by the genes on mouse chromosome 10. The C57BL/6J (B6) strain and C57BL/6J-Chr 10(A/J)/NaJ (B6.A10) consomic strain which carries the A/J chromosome 10 on a B6 strain background were compared. The B6.A10 mice compared to B6 were larger in body weight (p < 0...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28167230/adaptation-to-a-blood-pressure-telemetry-system-revealed-by-measures-of-activity-agility-and-operant-learning-in-mice
#14
Anfisa Popova, Darya Tsvirkun, Oleg Dolgov, Konstantin Anokhin, Jeffrey Alberts, Evgeniia Lagereva, Marc-Antoine Custaud, Guillemette Gauquelin-Koch, Olga Vinogradova, Alexander Andreev-Andrievskiy
INTRODUCTION: Implantable telemetry enables continuous monitoring of physiological functions in freely moving animals and can greatly complement pharmacological research. Despite its miniaturization, a sensor/transmitter constitutes 5% or more of a mouse's bodyweight. The aim of the present study was to evaluate whether factors related to the presence of a probe/transmitter influence the ambulatory activity, strength, agility, or operant, motivated behaviors of this small rodent. METHODS: Adult male mice (C57BL/6N, 22-25g, 9-10weeks; implanted n=26, intact n=45) were evaluated during week-long tests, conducted three and eight weeks after surgical implantation of the PA-C10 blood pressure probe...
February 3, 2017: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/28166612/acute-exercise-activates-p38-mapk-and-increases-the-expression-of-telomere-protective-genes-in-cardiac-muscle
#15
Andrew T Ludlow, Laila Gratidao, Lindsay W Ludlow, Espen E Spangenburg, Stephen M Roth
Age is the greatest risk factor for cardiovascular disease. Telomere length is shorter in the hearts of aged mice compared to young mice, and short telomere length has been associated with an increased risk of cardiovascular disease. One year of voluntary wheel running exercise attenuates the age-associated loss of telomere length and results in altered gene expression of telomere length maintaining and genome stabilizing proteins in heart tissue of mice. Understanding the early adaptive response of the heart to an endurance exercise bout is paramount to understanding the impact of endurance exercise on heart tissue and cells...
February 6, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28163011/aerobic-endurance-training-improves-nonalcoholic-fatty-liver-disease-nafld-features-via-mir-33-dependent-autophagy-induction-in-high-fat-diet-fed-mice
#16
Parvin Ghareghani, Mehrnoosh Shanaki, Saeideh Ahmadi, Ali Reza Khoshdel, Neda Rezvan, Reza Meshkani, Maryam Delfan, Sattar Gorgani-Firuzjaee
Due to changes in life style, obesity and obesity related complication such as insulin resistance, type 2 diabetes and non-alcoholic fatty liver disease caused worldwide health problems. Regular exercise has been frequently prescribed to combat metabolic complication of obesity but its molecular mechanism has not been fully illustrated. We investigated molecular mechanism of lipid lowering effect of exercise training in high fat diet fed mice by focusing on miR-33 expression and autophagy pathway. 24 mice were assigned to normal chow (NC) (n=8), high-fat diet (HFD) (n=16) group and subjected to NC and HFD for 13-weeks...
February 2, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28161898/the-relationship-between-loading-history-and-proximal-femoral-diaphysis-cross-sectional-geometry
#17
Sirpa Niinimäki, Nathaniel Narra, Laura Härkönen, Shinya Abe, Riku Nikander, Jari Hyttinen, Christopher Knüsel, Harri Sievänen
OBJECTIVES: We investigated the relationship between loading history and bone biomechanical properties used in physical activity reconstructions. These bone properties included bone bending and torsional strength (J), cortical area (CA), the direction of the major axis (theta angle), and element shape ratios determined from cross sections of standardized bone length. In addition, we explored the applicability of anatomically determined cross sections. METHODS: Our material consisted of hip and proximal thigh magnetic resonance images of Finnish female athletes (N = 91) engaged in high-jump, triple-jump, endurance running, swimming, power-lifting, soccer and squash; along with a group of active non-athlete individuals (N = 20)...
February 5, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28150178/the-effect-of-concurrent-plyometric-training-versus-submaximal-aerobic-cycling-on-rowing-economy-peak-power-and-performance-in-male-high-school-rowers
#18
Julian D Egan-Shuttler, Rohan Edmonds, Cassandra Eddy, Veronica O'Neill, Stephen J Ives
BACKGROUND: Plyometric training has been shown to increase muscle power, running economy, and performance in athletes. Despite its use by rowing coaches, it is unknown whether plyometrics might improve rowing economy or performance. The purpose was to determine if plyometric training, in conjunction with training on the water, would lead to improved rowing economy and performance. METHODS: Eighteen male high school rowers were assigned to perform 4 weeks of either plyometric training (PLYO, n = 9) or steady-state cycling below ventilatory threshold (endurance, E, n = 9), for 30 min prior to practice on the water (matched for training volume) 3 days per week...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28149382/10-km-running-performance-predicted-by-a-multiple-linear-regression-model-with-allometrically-adjusted-variables
#19
Cesar C C Abad, Ronaldo V Barros, Romulo Bertuzzi, João F L Gagliardi, Adriano E Lima-Silva, Mike I Lambert, Flavio O Pires
The aim of this study was to verify the power of VO2max, peak treadmill running velocity (PTV), and running economy (RE), unadjusted or allometrically adjusted, in predicting 10 km running performance. Eighteen male endurance runners performed: 1) an incremental test to exhaustion to determine VO2max and PTV; 2) a constant submaximal run at 12 km·h(-1) on an outdoor track for RE determination; and 3) a 10 km running race. Unadjusted (VO2max, PTV and RE) and adjusted variables (VO2max(0.72), PTV(0.72) and RE(0...
June 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28149368/the-influence-of-the-gait-related-arm-swing-on-elevation-gain-measured-by-sport-watches
#20
Rahel Ammann, Wolfgang Taube, Matthias Neuhaus, Thomas Wyss
The elevation gain is an important contributor to the total workload in endurance sports. The purpose of this study was to evaluate the influence of the arm swing on elevation gain in three sport watches (Garmin® Forerunner 910XT, Polar® RS800CX and Suunto® Ambit2) on a flat 400 m outdoor track. Altogether, a total of 120 repetitions of 1,200 m were performed at self-selected speeds corresponding to strolling, walking, jogging and running. During the assessment two devices of each sport watch, one secured on the hip and one on the wrist, were worn by the participants...
June 1, 2016: Journal of Human Kinetics
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