keyword
MENU ▼
Read by QxMD icon Read
search

First generation antipsychotics

keyword
https://www.readbyqxmd.com/read/29145545/treatment-of-alcohol-induced-psychotic-disorder-alcoholic-hallucinosis-a-systematic-review
#1
Barkat Masood, Peter Lepping, Dmitry Romanov, Rob Poole
Aims: To evaluate the effectiveness of evidence based treatments for alcohol-induced psychotic disorder (AIPD) as described by ICD-10 and DSM-5, a condition that is distinct from schizophrenia and has a close relationship with alcohol withdrawal states. Method: Systematic review using PRISMA guidelines. Results: Of 6205 abstracts found, fifteen studies and ten case reports met criteria and were examined. Larger studies examined the use of first-generation antipsychotic drugs, reporting full or partial remission in most patients...
November 14, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29132553/dysregulation-of-glucose-metabolism-since-young-adulthood-increases-the-risk-of-cardiovascular-diseases-in-patients-with-bipolar-disorder
#2
Pao-Huan Chen, Yen-Kuang Lin, Chi-Kang Chang, Shuo-Ju Chiang, Shang-Ying Tsai
Aging patients with bipolar disorder (BD) are at a high risk of cardiovascular diseases (CVDs). However, few studies have directly examined the association between metabolic risks and CVDs in patients with BD across the lifespan. Therefore, the aim of this study was to determine lifetime metabolic risk factors for CVDs in patients with BD. We recruited BD-I patients who were more than 50 years old and had had at least one psychiatric hospitalization. Patients who had a cardiologist-confirmed CVD diagnosis (ICD-9 code 401-414) were assigned to the case group...
December 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/29114100/successful-treatment-of-severe-tardive-dyskinesia-with-valbenazine-including-a-patient-s-perspective
#3
Richard C Josiassen, Dawn M Filmyer, Jack Gillean, Syed Sikandar Shah, Tyler E Dietterich, Rita A Shaughnessy
BACKGROUND Tardive dyskinesia (TD) is a chronic involuntary movement disorder frequently induced by dopamine receptor blockers, particularly first-generation antipsychotics. Until recently, management of TD was restricted to lowering the dose of the current medication, switching to another medication, or using off-label treatments with insufficient evidence of efficacy. Valbenazine, a vesicular monoamine transporter-2 (VMAT2) inhibitor, became the first drug to be approved by the FDA specifically for the treatment of TD...
November 8, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29110139/the-place-of-antipsychotics-in-the-therapy-of-anxiety-disorders-and-obsessive-compulsive-disorders
#4
REVIEW
Baptiste Pignon, Chloé Tezenas du Montcel, Louise Carton, Antoine Pelissolo
PURPOSE OF REVIEW: The purpose of this review was to assess and present the findings up to this date on the efficacy of antipsychotics in the treatment of generalized anxiety disorders (GAD), social anxiety disorders (SAD), panic disorders (PD), and obsessive-compulsive disorders (OCD), mostly based on published randomized controlled trials (RCTs) or on open-label studies when RCT were lacking. RECENT FINDINGS: Quetiapine could be recommended in patients with GAD...
November 7, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29107449/risk-of-gastrointestinal-hypomotility-in-schizophrenia-and-schizoaffective-disorder-treated-with-antipsychotics-a-retrospective-cohort-study
#5
Hsing-Kang Chen, Chia-Jung Hsieh
OBJECTIVE: The risk of gastrointestinal hypomotility (GIHM) with the use of antipsychotic medications in patients with schizophrenia remains inadequately recognized. The aim of this study was to explore the incidence of GIHM and its risks in patients with schizophrenia treated with antipsychotics. METHODS: We conducted a retrospective cohort study using the National Health Insurance Research Database. We identified adult (≥ 20years of age) patients with a first-time diagnosis of schizophrenia or schizoaffective disorder in the Registry for Catastrophic Illness Patients during the period from 2001 to 2011...
October 26, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29105246/role-of-potentially-inappropriate-medication-use-in-rehabilitation-outcomes-for-geriatric-patients-after-strokes
#6
Eiji Kose, Toshiyuki Hirai, Toshiichi Seki, Hiroyuki Hayashi
AIM: The effect of the use of potentially inappropriate medications (PIM) on mortality and functional outcome after strokes is unclear in Japan. The aim of the present study was to establish whether treatment with PIM affects functional improvements among geriatric patients convalescing after strokes. METHODS: This retrospective longitudinal study included consecutive geriatric patients admitted and discharged from convalescent rehabilitation wards for stroke between 2010 and 2016...
November 3, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29093685/bipolar-spectrum-disorders-in-male-youth-the-interplay-between-symptom-severity-inflammation-steroid-secretion-and-body-composition
#7
REVIEW
Andreas Walther, Marlene Penz, Daniela Ijacic, Timothy R Rice
The morbidity and societal burden of youth bipolar spectrum disorders (BSD) are high. These disorders are multisystemic in that adult populations there are clear interactions with inflammatory processes and steroidal physiological systems. There are much less data concerning these areas of study in youth populations with BSD. This is surprising given the association of youth-onset BSD with puberty and its associated physiological changes. In this mini-review, we overview the theoretical role of inflammatory processes and steroidal physiological systems in youth BSD, describe the greater literature in adult populations, detail the literature in youth populations when available, and overview current proposed molecular mechanistic pathways and interaction effects based on the available data...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29075885/long-term-metabolic-effects-of-aripiprazole-ziprasidone-and-quetiapine-a-pragmatic-clinical-trial-in-drug-na%C3%A3-ve-patients-with-a-first-episode-of-non-affective-psychosis
#8
Javier Vázquez-Bourgon, Rocío Pérez-Iglesias, Víctor Ortiz-García de la Foz, Paula Suárez Pinilla, Álvaro Díaz Martínez, Benedicto Crespo-Facorro
INTRODUCTION: The use of second-generation antipsychotics (SGA) has been associated with metabolic changes. However, there are differences in the metabolic profile between SGAs. We have previously observed that ziprasidone had a more benign early metabolic profile compared to aripiprazole and quetiapine. However, a long-term follow-up is preferred to detect clinically relevant impairment in metabolic parameters. We aimed to compare the effect of aripiprazole, ziprasidone, and quetiapine on metabolic measures in first-episode non-affective psychosis patients after 1 year of treatment...
October 26, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/29075309/weight-changes-before-and-after-lurasidone-treatment-a-real-world-analysis-using-electronic-health-records
#9
Jonathan M Meyer, Daisy S Ng-Mak, Chien-Chia Chuang, Krithika Rajagopalan, Antony Loebel
BACKGROUND: Severe and persistent mental illnesses, such as schizophrenia and bipolar disorder, are associated with increased risk of obesity compared to the general population. While the association of lurasidone and lower risk of weight gain has been established in short and longer-term clinical trial settings, information about lurasidone's association with weight gain in usual clinical care is limited. This analysis of usual clinical care evaluated weight changes associated with lurasidone treatment in patients with schizophrenia or bipolar disorder...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29069112/systematic-review-of-recent-guidelines-for-pharmacological-treatments-of-bipolar-disorders-in-adults
#10
Stephen Hammett, Nagy A Youssef
BACKGROUND: To examine the similarities and differences among practice guidelines for managing bipolar disorders (BDs) in adults. METHODS: A literature search in PubMed/Medline was performed using multiple search terms and bibliographies for guidelines from July 2013 (since FDA approval of lurasidone) to June 2017. RESULTS: Six treatment guidelines for BDs in adults were identified. These guidelines showed consensus on first-line treatment of mania (moodstabilizer and/or an antipsychotic), and most first-line medications for bipolar depression...
November 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/29048190/the-efficacy-and-tolerability-of-paliperidone-in-mania-of-bipolar-disorder-a-preliminary-meta-analysis
#11
Han-Yung Chang, Ping-Tao Tseng, Brendon Stubbs, Che-Sheng Chu, Dian-Jeng Li, Michele Fornaro, Andre Carvalho, Marco Solmi, Nicola Veronese, Eduard Vieta, Tien-Yu Chen, Yen-Wen Chen, Pao-Yen Lin, Philip Chik-Keung Chow
Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. This is the first meta-analysis to evaluate the efficacy, safety, and tolerability of paliperidone for the treatment of BD. We performed a systematic search of the literature using major electronic databases from inception to January 27, 2017. Randomized control trials (RCTs) investigating paliperidone treatment among patients with BD versus a placebo or other second-generation antipsychotics were included...
October 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29046716/a-multi-national-comparison-of-antipsychotic-drug-use-in-children-and-adolescents-2005-2012
#12
Luuk J Kalverdijk, Christian J Bachmann, Lise Aagaard, Mehmet Burcu, Gerd Glaeske, Falk Hoffmann, Irene Petersen, Catharina C M Schuiling-Veninga, Linda P Wijlaars, Julie M Zito
Over the last decades, an increase in antipsychotic (AP) prescribing and a shift from first-generation antipsychotics (FGA) to second-generation antipsychotics (SGA) among youth have been reported. However, most AP prescriptions for youth are off-label, and there are worrying long-term safety data in youth. The objective of this study was to assess multinational trends in AP use among children and adolescents. A repeated cross-sectional design was applied to cohorts from varied sources from Denmark, Germany, the Netherlands, the United Kingdom (UK) and the United States (US) for calendar years 2005/2006-2012...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/29037339/-beyond-cognitive-impairment-neuropsychiatric-symptoms-in-neurodegenerative-dementias
#13
Luisa Fernanda Ahunca Velásquez
As life expectancy increases, the number of people diagnosed with neurodegenerative dementia also increases. Although cognitive impairment is central in dementia, neuropsychiatric symptoms (NPS) are very important because they increase both direct and indirect costs by generating greater morbidity, caregiver distress, use of medication and institutionalisation. Furthermore, it is important to understand the nature of NPS, since they can vary across the different types of dementia and may provide useful clinical information regarding the aetiology of cognitive impairment...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29034139/aripiprazole-induced-neutropenia-in-a-seven-year-old-male-a-case-report
#14
Muhammad Hassan Majeed, Ali Ahsan Ali
Blood dyscrasias are the widely known side effect of the second-generation antipsychotic medications. Aripiprazole rarely causes hematological side effects and it is considered relatively safe. We present the case report of a seven-year-old male who developed acute neutropenia a week after starting aripiprazole. His absolute neutrophil count (ANC) arose spontaneously once the medication was stopped. Clinicians should periodically check ANC in the patients taking aripiprazole as neutropenia could be lethal in extreme cases...
August 11, 2017: Curēus
https://www.readbyqxmd.com/read/29028643/pharmacotherapy-of-borderline-personality-disorder-replacing-confusion-with-prudent-pragmatism
#15
Vladan Starcevic, Aleksandar Janca
PURPOSE OF REVIEW: The article aims to examine trends in the pharmacological treatment of borderline personality disorder (BPD) and shed more light on the attendant controversies. RECENT FINDINGS: Although specialized, BPD-centred psychotherapy is considered first-line treatment for BPD and no psychotropic drug has been licensed for BPD, medications are frequently prescribed in the management of this condition. Various classes of psychopharmacological agents are used for BPD and there is a prominent polypharmacy...
October 11, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/29022654/epidemiology-prevention-and-assessment-of-tardive-dyskinesia-and-advances-in-treatment
#16
REVIEW
Christoph U Correll, John M Kane, Leslie L Citrome
​​ Tardive dyskinesia (TD) is a disorder characterized by involuntary movements, typically of the orofacial muscles and also of the extremities and other muscle groups. The condition is associated with exposure to dopamine receptor blocking agents, including antipsychotics. Because the indications and off-label uses for these agents have expanded over the last 2 decades, a larger number of patients are receiving antipsychotic medications than in the past. While evidence suggests that patients being treated with second-generation antipsychotics have less risk for developing TD than those treated with first-generation antipsychotics, the decreased risk is not as great as was originally expected...
September 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29019422/pharmacotherapy-of-mood-disorders-and-psychosis-in-pre-and-post-natal-women
#17
Beth Smith, Steven L Dubovsky
Untreated mood and psychotic disorders can have substantial adverse impacts on the patient, the fetus and the family, while treatment can ameliorate such problems. To address concerns by clinicians about the risks of psychotropic medications, this review addresses the risk/benefit analysis of somatic therapies for psychiatric disorders during pregnancy and lactation. Areas covered: All available research was reviewed on the impact on pregnancy and breastfeeding of mood and psychotic disorders, and of antidepressants, mood stabilizers, antipsychotic drugs, and electroconvulsive therapy...
November 7, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28988102/number-of-illness-episodes-as-predictor-of-residual-symptoms-in-major-depressive-disorder
#18
Gianluca Serafini, Jacopo Nebbia, Nicolò Cipriani, Claudia Conigliaro, Denise Erbuto, Maurizio Pompili, Mario Amore
Notwithstanding major depressive disorder (MDD) is a recurring and chronic condition, relatively few variables have consistently been shown to predict its course. Residual depressive symptoms may be associated with disability and functional impairment but few studies evaluated clinical correlates associated with these symptoms and their impact on functioning after adjustment for potential confounders. Therefore, our study aimed to investigate factors associated with residual depressive symptoms and their impact on the course of MDD...
September 12, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28975381/health-status-and-drug-use-1%C3%A2-year-before-and-1%C3%A2-year-after-skilled-nursing-home-admission-during-the-first-quarter-of-2013-in-france-a-study-based-on-the-french-national-health-insurance-information-system
#19
Alice Atramont, Dominique Bonnet-Zamponi, Isabelle Bourdel-Marchasson, Isabelle Tangre, Anne Fagot-Campagna, Philippe Tuppin
PURPOSE: Changes in prescribing practices following skilled nursing home (SNH) admission have not been clearly described in France. The study aimed to evaluate health status and drug use 1 year before and 1 year after admission to SNH. METHOD: People ≥ 65 years old admitted to SNH in the first quarter of 2013, covered by the national health insurance general scheme (69% of the population of this age) and still alive 1 year after admission were identified in a specific database (Resid-ehpad)...
October 3, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28974404/influence-of-venus-and-mars-in-the-cognitive-sky-of-schizophrenia-results-from-the-first-step-national-face-sz-cohort
#20
G Fond, L Boyer, M Leboyer, O Godin, P M Llorca, M Andrianarisoa, F Berna, L Brunel, B Aouizerate, D Capdevielle, I Chereau, T D'Amato, C Dubertret, J Dubreucq, C Faget, F Gabayet, J Mallet, D Misdrahi, R Rey, C Lancon, C Passerieux, P Roux, P Vidailhet, H Yazbek, F Schürhoff, E Bulzacka
OBJECTIVES: Sex differences can yield important clues regarding illness pathophysiology and its treatment. Schizophrenia (SZ) has a lower incidence rate, and a better prognosis, in women versus men. The present study investigated the cognitive profiles of both sexes in a large multi-centre sample of community-dwelling SZ patients. METHOD: 544 community-dwelling stable SZ subjects (141 women and 403 men; mean age 34.5±12.1 and 31.6±8.7years, respectively) were tested with a comprehensive battery of neuropsychological tests...
September 30, 2017: Schizophrenia Research
keyword
keyword
97706
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"