keyword
MENU ▼
Read by QxMD icon Read
search

CHO loading

keyword
https://www.readbyqxmd.com/read/27911415/extraction-of-plant-based-capsules-for-microencapsulation-applications
#1
Michael G Potroz, Raghavendra C Mundargi, Jae Hyeon Park, Ee-Lin Tan, Nam-Joon Cho
Microcapsules derived from plant-based spores or pollen provide a robust platform for a diverse range of microencapsulation applications. Sporopollenin exine capsules (SECs) are obtained when spores or pollen are processed so as to remove the internal sporoplasmic contents. The resulting hollow microcapsules exhibit a high degree of micromeritic uniformity and retain intricate microstructural features related to the particular plant species. Herein, we demonstrate a streamlined process for the production of SECs from Lycopodium clavatum spores and for the loading of hydrophilic compounds into these SECs...
November 9, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27900731/the-validity-and-reliability-of-the-korean-version-of-the-stigma-scale-for-chronic-illness-8-items-ssci-8-in-patients-with-neurological-disorders
#2
Sung-Hee Yoo, Sung Reul Kim, Hyang Sook So, Hyang-In Cho Chung, Duck Hee Chae, Myeong-Kyu Kim, Byeong C Kim, Man-Seok Park, Seung-Han Lee, Tai-Seung Nam, Helena Correia, David Cella
PURPOSE: The aim of this study was to develop a Korean version of the Stigma Scale for Chronic Illness 8-items (SSCI-8) and then assess its reliability and construct validity among patients with neurological conditions. METHOD: Patients diagnosed with stroke, Parkinson's disease, epilepsy, multiple sclerosis, myasthenia gravis, and amyotrophic lateral sclerosis were recruited. Reliability was assessed for internal consistency with Cronbach's alpha coefficient. Exploratory factor analysis (EFA) was used to extract potential factors of Korean SSCI-8...
November 29, 2016: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27895468/increased-localized-delivery-of-piroxicam-by-cationic-nanoparticles-after-intra-articular-injection
#3
Sung Rae Kim, Myoung Jin Ho, Sang Hyun Kim, Ha Ra Cho, Han Sol Kim, Yong Seok Choi, Young Wook Choi, Myung Joo Kang
Piroxicam (PRX), a potent nonsteroidal anti-inflammatory drug, is prescribed to relieve postoperative and/or chronic joint pain. However, its oral administration often results in serious gastrointestinal adverse effects including duodenal ulceration. Thus, a novel cationic nanoparticle (NP) was explored to minimize the systemic exposure and increase the retention time of PRX in the joint after intra-articular (IA) injection, by forming micrometer-sized electrostatic clusters with endogenous hyaluronic acid (HA) in the synovial cavity...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27881046/preparation-and-characterization-of-bee-venom-loaded-plga-particles-for-sustained-release
#4
Min-Ho Park, Hye-Suk Jun, Jong-Woon Jeon, Jin-Kyu Park, Bong-Joo Lee, Guk-Hyun Suh, Jeong-Sook Park, Cheong-Weon Cho
Bee venom-loaded poly(lactic-co-glycolic acid) (PLGA) particles were prepared by double emulsion-solvent evaporation, and characterized for a sustained-release system. Factors such as the type of organic solvent, the amount of bee venom and PLGA, the type of PLGA, the type of polyvinyl alcohol, and the emulsification method were considered. Physicochemical properties, including the encapsulation efficiency, drug loading, particle size, zeta-potential, and surface morphology were examined by Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetry (DSC), and X-ray diffraction (XRD)...
November 24, 2016: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/27877138/a-ketogenic-diet-in-rodents-elicits-improved-mitochondrial-adaptations-in-response-to-resistance-exercise-training-compared-to-an-isocaloric-western-diet
#5
Hayden W Hyatt, Wesley C Kephart, A Maleah Holland, Petey Mumford, C Brooks Mobley, Ryan P Lowery, Michael D Roberts, Jacob M Wilson, Andreas N Kavazis
Purpose: Ketogenic diets (KD) can facilitate weight loss, but their effects on skeletal muscle remain equivocal. In this experiment we investigated the effects of two diets on skeletal muscle mitochondrial coupling, mitochondrial complex activity, markers of oxidative stress, and gene expression in sedentary and resistance exercised rats. Methods: Male Sprague-Dawley rats (9-10 weeks of age, 300-325 g) were fed isocaloric amounts of either a KD (17 g/day, 5.2 kcal/g, 20.2% protein, 10.3% CHO, 69.5% fat, n = 16) or a Western diet (WD) (20 g/day, 4...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27822040/raspberry-like-poly-%C3%AE-glutamic-acid-hydrogel-particles-for-ph-dependent-cell-membrane-passage-and-controlled-cytosolic-delivery-of-antitumor-drugs
#6
Sun-Hee Cho, Ji Hyeon Hong, Young-Woock Noh, Eunji Lee, Chang-Soo Lee, Yong Taik Lim
In this research, we synthesized bioderived poly(amino acid) hydrogel particles that showed pH-dependent membrane-disrupting properties and controlled cytosolic delivery of antitumor drugs. Poly(γ-glutamic acid) (γ-PGA) that has been produced extensively using bacteria, especially those of Bacillus subtilis species, was modified with cholesterol (γ-PGA/Chol), and the γ-PGA/Chol conjugates were used to form polymeric nanoparticles the size of 21.0±1.1 nm in aqueous solution. When the polymeric nanoparticles were mixed with doxorubicin (Dox), raspberry-like hydrogel particles (RBHPs) were formed by the electrostatic interaction between the cationically charged Dox and the anionically charged nanoparticles...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27817924/new-particle-formation-in-china-current-knowledge-and-further-directions
#7
Zhibin Wang, Zhijun Wu, Dingli Yue, Dongjie Shang, Song Guo, Junying Sun, Aijun Ding, Lin Wang, Jingkun Jiang, Hai Guo, Jian Gao, Hing Cho Cheung, Lidia Morawska, Melita Keywood, Min Hu
New particle formation (NPF) studies have been conducted in China since 2004. Formation of new atmospheric aerosol particles has been observed to take place in diverse environments, even under the circumstances of high pre-existing particle loading, challenging the traditional and present understanding of the physicochemical nucleation mechanisms, which have been proposed based on the investigations in clean environments and under laboratory experimental conditions. This paper summarizes the present status and gaps in understanding NPF in China and discusses the main directions opening for future research...
January 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27809454/long-term-real-world-entecavir-therapy-in-treatment-na%C3%A3-ve-hepatitis-b-patients-base-line-hepatitis-b-virus-dna-and-hepatitis-b-surface-antigen-levels-predict-virologic-response
#8
Ju-Yeon Cho, Won Sohn, Dong-Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo, Joon Hyeok Lee
Background/Aims: Entecavir is a potent nucleoside analogue with high efficacy and barrier for resistance. We aimed to investigate the long-term efficacy and viral resistance rate of entecavir and explore the factors associated with virologic response, including quantitative hepatitis B surface antigen (qHBsAg) levels. Methods: One thousand and nine treatment-naïve chronic hepatitis B (CHB) patients were evaluated for cumulative rates of virologic response, biochemical response, and entecavir mutations...
November 4, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27800217/increased-osteoinductivity-and-mineralization-by-minimal-concentration-of-bone-morphogenetic-protein-2-loaded-onto-biphasic-calcium-phosphate-in-a-rabbit-sinus
#9
Jae-Shin Kim, Jae-Kook Cha, Jung-Seok Lee, Seong-Ho Choi, Kyoo-Sung Cho
PURPOSE: The purpose of the present study was to evaluate the effectiveness of a minimal concentration of bone morphogenetic protein-2 (BMP-2) in terms of quantitative and qualitative analyses of newly formed bone in a rabbit maxillary sinus model. METHODS: In 7 rabbits, sinus windows were prepared bilaterally. Biphasic calcium phosphate (BCP) loaded with 0.05 mg/mL BMP-2 was grafted into one sinus (the BMP group) and saline-soaked BCP was placed into the other (the control group) in each animal...
October 2016: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/27771723/cortical-responses-and-shape-complexity-of-stereoscopic-image-a-simultaneous-eeg-meg-study
#10
Hohyun Cho, Min-Koo Kang, Sangtae Ahn, Moonyoung Kwon, Kuk-Jin Yoon, Kiwoong Kim, Sung Chan Jun
BACKGROUND/AIMS: In exploring human factors, stereoscopic 3D images have been used to investigate the neural responses associated with excessive depth, texture complexity, and other factors. However, the cortical oscillation associated with the complexity of stereoscopic images has been studied rarely. Here, we demonstrated that the oscillatory responses to three differently shaped 3D images (circle, star, and bat) increase as the complexity of the image increases. METHODS: We recorded simultaneous EEG/MEG for three different stimuli...
October 24, 2016: Neuro-Signals
https://www.readbyqxmd.com/read/27760120/break-induced-telomere-synthesis-underlies-alternative-telomere-maintenance
#11
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg
Homology-directed DNA repair is essential for genome maintenance through templated DNA synthesis. Alternative lengthening of telomeres (ALT) necessitates homology-directed DNA repair to maintain telomeres in about 10-15% of human cancers. How DNA damage induces assembly and execution of a DNA replication complex (break-induced replisome) at telomeres or elsewhere in the mammalian genome is poorly understood. Here we define break-induced telomere synthesis and demonstrate that it utilizes a specialized replisome, which underlies ALT telomere maintenance...
October 19, 2016: Nature
https://www.readbyqxmd.com/read/27738501/lipid-emulsion-inhibits-vasodilation-induced-by-a-toxic-dose-of-bupivacaine-by-suppressing-bupivacaine-induced-pkc-and-cpi-17-dephosphorylation-but-has-no-effect-on-vasodilation-induced-by-a-toxic-dose-of-mepivacaine
#12
Hyunhoo Cho, Seong Ho Ok, Seong Chun Kwon, Soo Hee Lee, Jiseok Baik, Sebin Kang, Jiah Oh, Ju-Tae Sohn
BACKGROUND: The goal of this in vitro study was to investigate the effect of lipid emulsion on vasodilation caused by toxic doses of bupivacaine and mepivacaine during contraction induced by a protein kinase C (PKC) activator, phorbol 12,13-dibutyrate (PDBu), in an isolated endothelium-denuded rat aorta. METHODS: The effects of lipid emulsion on the dose-response curves induced by bupivacaine or mepivacaine in an isolated aorta precontracted with PDBu were assessed...
October 2016: Korean Journal of Pain
https://www.readbyqxmd.com/read/27723306/highly-durable-supportless-pt-hollow-spheres-designed-for-enhanced-oxygen-transport-in-cathode-catalyst-layers-of-proton-exchange-membrane-fuel-cells
#13
Didem C Dogan, Seonghun Cho, Sun-Mi Hwang, Young-Min Kim, Hwanuk Guim, Tae-Hyun Yang, Seok-Hee Park, Gu-Gon Park, Sung-Dae Yim
Supportless Pt catalysts have several advantages over conventional carbon-supported Pt catalysts in that they are not susceptible to carbon corrosion. However, the need for high Pt loadings in membrane electrode assemblies (MEAs) to achieve state-of-the-art fuel cell performance has limited their application in proton exchange membrane fuel cells. Herein, we report a new approach to the design of a supportless Pt catalyst in terms of catalyst layer architecture, which is crucial for fuel cell performance as it affects water management and oxygen transport in the catalyst layers...
October 10, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27709740/effects-of-organic-loading-rate-on-hydrogen-and-volatile-fatty-acid-production-and-microbial-community-during-acidogenic-hydrogenesis-in-a-continuous-stirred-tank-reactor-using-molasses-wastewater
#14
J Yun, K-S Cho
AIMS: Microbial community associated with hydrogen production and volatile fatty acids (VFAs) accumulation was characterized in acidogenic hydrogenesis using molasses wastewater as a feedstock. METHODS AND RESULTS: Hydrogen and VFAs production were measured under an organic loading rate (OLR) from 19 to 35 g-COD l(-1)  day(-1) . The active microbial community was analysed using RNA-based massively parallel sequencing technique, and their correlation patterns were analysed using networking analysis...
December 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/27678247/ocular-drug-delivery-through-phema-hydrogel-contact-lenses-co-loaded-with-lipophilic-vitamins
#15
Dasom Lee, Seungkwon Cho, Hwa Sung Park, Inchan Kwon
Ocular drug delivery through hydrogel contact lenses has great potential for the treatment of ocular diseases. Previous studies showed that the loading of lipophilic vitamin E to silicone-hydrogel contact lenses was beneficial in ocular drug delivery. We hypothesized that vitamin E loading to another type of popular hydrogel contact lenses, pHEMA-hydrogel contact lenses, improves ocular drug delivery by increasing the drug loading or the duration of drug release. Loading of vitamin E to pHEMA-hydrogel contact lenses significantly increased the loading of a hydrophilic drug surrogate (Alexa Fluor 488 dye) and two hydrophilic glaucoma drugs (timolol and brimonidine) to the lenses by 37...
September 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27677914/effect-of-glycemic-index-of-a-pre-exercise-meal-on-endurance-exercise-performance-a-systematic-review-and-meta-analysis
#16
Catriona A Burdon, Inge Spronk, Hoi Lun Cheng, Helen T O'Connor
BACKGROUND: Low glycemic index (GI) pre-exercise meals may enhance endurance performance by maintaining euglycemia and altering fuel utilization. However, evidence for performance benefits is equivocal. OBJECTIVE: To evaluate the effect of a low GI (LGI) versus a high GI (HGI) pre-exercise meal on endurance performance using meta-analyses. METHODS: Data sources included MEDLINE, SPORTDiscus, AUSPORT, AusportMed, Web of Science, and Scopus...
September 28, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27668194/the-effects-of-alveolar-bone-loss-and-miniscrew-position-on-initial-tooth-displacement-during-intrusion-of-the-maxillary-anterior-teeth-finite-element-analysis
#17
Sun-Mi Cho, Sung-Hwan Choi, Sang-Jin Sung, Hyung-Seog Yu, Chung-Ju Hwang
OBJECTIVE: The aim of this study was to determine the optimal loading conditions for pure intrusion of the six maxillary anterior teeth with miniscrews according to alveolar bone loss. METHODS: A three-dimensional finite element model was created for a segment of the six anterior teeth, and the positions of the miniscrews and hooks were varied after setting the alveolar bone loss to 0, 2, or 4 mm. Under 100 g of intrusive force, initial displacement of the individual teeth in three directions and the degree of labial tilting were measured...
September 2016: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/27650939/preventive-effects-of-poloxamer-188-on-muscle-cell-damage-mechanics-under-oxidative-stress
#18
Sing Wan Wong, Yifei Yao, Ye Hong, Zhiyao Ma, Stanton H L Kok, Shan Sun, Michael Cho, Kenneth K H Lee, Arthur F T Mak
High oxidative stress can occur during ischemic reperfusion and chronic inflammation. It has been hypothesized that such oxidative challenges could contribute to clinical risks such as deep tissue pressure ulcers. Skeletal muscles can be challenged by inflammation-induced or reperfusion-induced oxidative stress. Oxidative stress reportedly can lower the compressive damage threshold of skeletal muscles cells, causing actin filament depolymerization, and reduce membrane sealing ability. Skeletal muscles thus become easier to be damaged by mechanical loading under prolonged oxidative exposure...
September 20, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/27647898/a-single-heterologously-expressed-plant-cellulose-synthase-isoform-is-sufficient-for-cellulose-microfibril-formation-in-vitro
#19
Pallinti Purushotham, Sung Hyun Cho, Sara M Díaz-Moreno, Manish Kumar, B Tracy Nixon, Vincent Bulone, Jochen Zimmer
Plant cell walls are a composite material of polysaccharides, proteins, and other noncarbohydrate polymers. In the majority of plant tissues, the most abundant polysaccharide is cellulose, a linear polymer of glucose molecules. As the load-bearing component of the cell wall, individual cellulose chains are frequently bundled into micro and macrofibrils and are wrapped around the cell. Cellulose is synthesized by membrane-integrated and processive glycosyltransferases that polymerize UDP-activated glucose and secrete the nascent polymer through a channel formed by their own transmembrane regions...
October 4, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27632260/effect-of-the-coronal-wall-thickness-of-dental-implants-on-the-screw-joint-stability-in-the-internal-implant-abutment-connection
#20
Ji-Hye Lee, Yoon-Hyuk Huh, Chan-Jin Park, Lee-Ra Cho
PURPOSE: To evaluate the effect of implant coronal wall thickness on load-bearing capacity and screw joint stability. MATERIALS AND METHODS: Experimental implants were customized after investigation of the thinnest coronal wall thickness of commercially available implant systems with a regular platform diameter. Implants with four coronal wall thicknesses (0.2, 0.3, 0.4, and 0.5 mm) were fabricated. Three sets of tests were performed. The first set was a failure test to evaluate load-bearing capacity and elastic limit...
September 2016: International Journal of Oral & Maxillofacial Implants
keyword
keyword
97689
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"