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https://www.readbyqxmd.com/read/29147099/changes-in-quality-characteristics-of-pork-patties-containing-antioxidative-fish-skin-peptide-or-fish-skin-peptide-loaded-nanoliposomes-during-refrigerated-storage
#1
Jing-Jing Bai, Jung-Gyu Lee, Sang-Yoon Lee, Soojin Kim, Mi-Jung Choi, Youngjae Cho
Marine fish skin peptides (FSP) have been widely studied due to their antioxidant and antimicrobial properties. We aimed to use a natural antioxidant, FSP, to replacing synthetic preservatives in a pork patty model, which is safer for human body. Moreover, nano-liposome technology can be applied for masking the fishy smell and improving the stability of this peptide. Therefore, in this study, the effects of FSP and FSP-loaded liposomes (FSPL) on pork patty were evaluated through the tests of thiobarbituric acid reactive substances (TBARS), color, cooking loss, texture, volatile basic nitrogen (VBN), and the pH value, during 14 d of refrigerated (4°C) storage...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/29145824/observations-on-significant-hemodynamic-changes-caused-by-a-high-concentration-of-epidurally-administered-ropivacaine-correlation-and-prediction-study-of-stroke-volume-variation-and-central-venous-pressure-in-thoracic-epidural-anesthesia
#2
Jeong-Min Hong, Hyeon Jeong Lee, Young-Jae Oh, Ah Rhem Cho, Hyae Jin Kim, Do-Won Lee, Wang-Seok Do, Jae-Young Kwon, Haekyu Kim
BACKGROUND: Thoracic epidural anesthesia (TEA) exacerbates hypotension due to peripheral vasodilator effects following the use of general anesthetics. This study aimed to compare the hemodynamic changes caused by three different concentrations of epidural ropivacaine and to evaluate the performance of the stroke-volume variation (SVV) and central venous pressure (CVP) during TEA with general anesthesia. METHODS: A total of 120 patients were administered 8 mL of ropivacaine solution via epidural injection, following randomization into one of three groups based on the concentration of ropivacaine in the study solution: 0...
November 16, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/29141149/surface-modification-of-cisplatin-complexed-gold-nanoparticles-and-its-influence-on-colloidal-stability-drug-loading-and-release
#3
Jiaojie Tan, Tae Joon Cho, De-Hao Tsai, Jingyu Liu, John M Pettibone, Rian You, Vincent A Hackley, Michael R Zachariah
Cisplatin-complexed gold nanoparticles (PtII-AuNP) provide a promising strategy for chemo-radiation based anticancer drugs. Effective design of such platforms necessitates reliable assessment of surface engineering on a quantitative basis, and its influence on drug payload, stability and release. In this paper, polyethylene glycol (PEG) stabilized PtII-AuNP was synthesized as a model anti-tumor drug platform, where PtII is attached via a carboxyl terminated dendron ligand. Surface modification by PEG and its influence on drug loading, colloidal stability and drug release were assessed...
November 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29124674/the-cognitive-loci-of-the-display-and-task-relevant-set-size-effects-on-distractor-interference-evidence-from-a-dual-task-paradigm
#4
Bo Youn Park, Sujin Kim, Yang Seok Cho
The congruency effect of a task-irrelevant distractor has been found to be modulated by task-relevant set size and display set size. The present study used a psychological refractory period (PRP) paradigm to examine the cognitive loci of the display set size effect (dilution effect) and the task-relevant set size effect (perceptual load effect) on distractor interference. A tone discrimination task (Task 1), in which a response was made to the pitch of the target tone, was followed by a letter discrimination task (Task 2) in which different types of visual target display were used...
November 9, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29119005/differences-in-left-ventricular-functional-adaptation-to-arterial-stiffness-and-neurohormonal-activation-in-patients-with-hypertension-a-study-with-two-dimensional-layer-specific-speckle-tracking-echocardiography
#5
Darae Kim, Chi Young Shim, Geu-Ru Hong, Sungha Park, InJeong Cho, Hyuk-Jae Chang, Jong-Won Ha, Namsik Chung
Background: Arterial stiffness increases pressure load to the left ventricle (LV), leading to LV hypertrophy and subendocardial ischemia. Neurohormones stimulate myocardial fibrosis and LV dysfunction. We aimed to explore the associations of arterial stiffness and plasma aldosterone with multi-directional, layer-specific LV, and left atrial (LA) mechanical function in hypertensive patients. Methods: Layer-specific LV global longitudinal strain (GLS-trans, GLS-endo, GLS-epi), global circumferential strain (GCS-trans, GCS-endo, GCS-epi), LV torsional parameters, and LA global longitudinal strain (LA GLS) were analyzed by two-dimensional speckle tracking echocardiography in 195 hypertensive patients (110 men, mean age 55 years)...
2017: Clinical Hypertension
https://www.readbyqxmd.com/read/29116172/building-on-sub-arctic-soil-geopolymerization-of-muskeg-to-a-densified-load-bearing-composite
#6
Gregory R Waetzig, Junsang Cho, Max Lacroix, Sarbajit Banerjee
The marshy water-saturated soil typical of the sub-Arctic represents a considerable impediment to the construction of roads, thereby greatly hindering human habitation and geological excavation. Muskeg, the native water-laden topsoil characteristic of the North American sub-Arctic, represents a particularly vexing challenge for road construction. Muskeg must either be entirely excavated, or for direct construction on muskeg, a mix of partial excavation and gradual compaction with the strategic placement of filling materials must be performed...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29066894/poly-d-l-lactic-glycolic-acid-star-glucose-nanoparticles-for-glucose-transporter-and-hypoglycemia-mediated-tumor-targeting
#7
Ju-Hwan Park, Hyun-Jong Cho, Dae-Duk Kim
Poly((D,L)lactic-glycolic)acid-star glucose (PLGA-Glc) polymer-based nanoparticles (NPs) were fabricated for tumor-targeted delivery of docetaxel (DCT). NPs with an approximate mean diameter of 241 nm, narrow size distribution, negative zeta potential, and spherical shape were prepared. A sustained drug release pattern from the developed NPs was observed for 13 days. Moreover, drug release from PLGA-Glc NPs at acidic pH (endocytic compartments and tumor regions) was significantly improved compared with that observed at physiological pH (normal tissues and organs)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29060278/a-study-on-setting-of-the-fatigue-limit-of-temporary-dental-implants
#8
M H Kim, E J Cho, J W Lee, E K Kim, S H Yoo, C W Park
A temporary dental implant is a medical device which is temporarily used to support a prosthesis such as an artificial tooth used for restoring patient's masticatory function during implant treatment. It is implanted in the oral cavity to substitute for the role of tooth. Due to the aging and westernization of current Korean society, the number of tooth extraction and implantation procedures is increasing, leading to an increase in the use and development of temporary dental implants. Because an implant performs a masticatory function in place of a tooth, a dynamic load is repeatedly put on the implant...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29053623/transfer-efficient-face-routing-using-the-planar-graphs-of-neighbors-in-high-density-wsns
#9
Eun-Seok Cho, Yongbin Yim, Sang-Ha Kim
Face routing has been adopted in wireless sensor networks (WSNs) where topological changes occur frequently or maintaining full network information is difficult. For message forwarding in networks, a planar graph is used to prevent looping, and because long edges are removed by planarization and the resulting planar graph is composed of short edges, and messages are forwarded along multiple nodes connected by them even though they can be forwarded directly. To solve this, face routing using information on all nodes within 2-hop range was adopted to forward messages directly to the farthest node within radio range...
October 20, 2017: Sensors
https://www.readbyqxmd.com/read/29038104/safety-of-oral-dofetilide-reloading-for-treatment-of-atrial-arrhythmias
#10
Jae Hyung Cho, So Jin Youn, JoEllyn C Moore, Roxanne Kyriakakis, Carolyn Vekstein, Michael Militello, Stacy M Poe, Kathy Wolski, Patrick J Tchou, Niraj Varma, Mark J Niebauer, Mandeep Bhargava, Walid I Saliba, Oussama M Wazni, Bruce D Lindsay, Bruce L Wilkoff, Mina K Chung
BACKGROUND: Although dofetilide labeling states that the drug must be initiated or reinitiated with continuous electrocardiographic monitoring and in the presence of trained personnel, the risks of dofetilide reloading justifying repeat hospitalization have not been investigated. METHODS AND RESULTS: Patients admitted for dofetilide reloading for atrial arrhythmias were retrospectively reviewed. The need for dose adjustment and the incidence of torsades de pointes (TdP) were identified...
October 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29029102/nucleos-t-ide-analogue-treatment-for-adult-patients-with-hbeag-positive-chronic-infection-with-genotype-c-hepatitis-b-virus-a-nationwide-real-life-study
#11
Young Chang, Won Hyeok Choe, Dong Hyun Sinn, Jeong-Hoon Lee, Sang Hoon Ahn, Hyewon Lee, Jae-Jun Shim, Dae Won Jun, Soo Young Park, Joon Yeul Nam, Eun Ju Cho, Su Jong Yu, Dong Ho Lee, Jeong Min Lee, Yoon Jun Kim, So Young Kwon, Seung Woon Paik, Jung-Hwan Yoon
Background/Aim: Antiviral treatment for patients in HBeAg-positive chronic hepatitis B virus (HBV) infection is still controversial. We assessed whether antiviral treatment reduces liver disease progression in those patients. Methods: This study included consecutive patients that tested positive for HBeAg with an HBV DNA >20,000 IU/mL, ALT <40 IU/L and without evidence of cirrhosis in eight large-volume hospitals in Korea. The primary endpoint was the development of hepatocellular carcinoma (HCC) and the secondary endpoint was the development of cirrhosis...
September 23, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28984737/intravitreal-aflibercept-and-ranibizumab-injections-for-type-3-neovascularization
#12
Han Joo Cho, Hyun Ji Hwang, Hyoung Seok Kim, Jung Il Han, Dong Won Lee, Jong Woo Kim
PURPOSE: To compare the effectiveness of intravitreal injection of aflibercept with ranibizumab in patients with Type 3 neovascularization. METHODS: Sixty-three treatment-naive eyes with Type 3 neovascularization (58 patients) were retrospectively analyzed. The eyes had received intravitreal aflibercept or ranibizumab injections. All patients were treated using an initial series of three monthly loading injections, followed by further injections as required. The visual and anatomical outcomes of treatment were evaluated after 12 months...
October 3, 2017: Retina
https://www.readbyqxmd.com/read/28981997/facile-synthesis-of-composition-controlled-graphene-supported-ptpd-alloy-nanocatalysts-and-their-applications-in-methanol-electrooxidation-and-li-oxygen-batteries
#13
Seong Ji Ye, Hieu Trung Bui, Young Yun Kim, Kin Liao, Kyeong Min Cho, Hee-Tae Jung, Yongku Kang, Do Youb Kim, O Ok Park
In this article, we report a new and simple approach for the synthesis of uniformly dispersed PtPd alloy nanocatalysts supported on graphene nanoplatelets (GNPs) (PtPd-GNPs) through the introduction of bifunctional materials that can be used to modify the GNP surface and simultaneously reduce metal ions. Through the use of poly(4-styrenesulfonic acid), poly(vinyl pyrrolidone), poly(diallyldimethylammonium chloride), and poly(vinyl alcohol) as bifunctional materials, PtPd-GNPs can be produced using a procedure that is far simpler than previously reported methods...
October 5, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28978343/dietary-food-patterns-and-glucose-insulin-homeostasis-a-cross-sectional-study-involving-24-182-adult-americans
#14
Mohsen Mazidi, Andre Pascal Kengne, Dimitri P Mikhailidis, Peter P Toth, Kausik K Ray, Maciej Banach
AIM: To investigate the association of major dietary patterns with glucose and insulin homeostasis parameters in a large American sample. The association between dietary patterns (DP) derived via principal components analysis (PCA), with glucose/insulin homeostasis parameters was assessed. The likelihood of insulin resistance (IR) across the DPs quarters was also explored. METHOD: The United States National Health and Nutrition Examination Survey (NHANES) participants during 2005-2012 were included if they underwent measurement of dietary intake as well as glucose and insulin homeostasis parameters...
October 4, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28975732/a-novel-calcium-accumulating-peptide-gelatin-in-situ-forming-hydrogel-for-enhanced-bone-regeneration
#15
Beom Soo Jo, Yunki Lee, Jin Sook Suh, Yoon Shin Park, Hyun Jung Lee, Jue-Yeon Lee, Jaejin Cho, Gene Lee, Chong Pyoung Chung, Ki Dong Park, Yoon Jeong Park
Bioactive agents, including proteins and peptides, can be loaded into hydrogels to improve bone regenerative capacity with their controlled release. However, the current loading method has focused on physical mixing, which has limited release control. Therefore, alternative conjugation of bioactive agents with hydrogels is highly recommended. Direct chemical conjugation of synthetic peptides containing a functional moiety with a hydrogel would be ideal. Here, we synthesized a bioactive calcium accumulating peptide (CAP) containing a collagen binding motif (CBM), which can induce osteogenic differentiation...
October 4, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28972854/the-effect-of-milk-on-recovery-from-repeat-sprint-cycling-in-female-team-sport-athletes
#16
Paula Rankin, Michael J Lawlor, Frank A Hills, Phillip G Bell, Emma J Stevenson, Emma Cockburn
The consumption of milk post-eccentric exercise attenuates the effects of muscle damage in team-sport athletes. However, participation in team sport involves both concentric-eccentric loading and metabolic stress. Therefore, the aim of this study was to investigate the effects of post-exercise milk consumption on recovery from a cycling protocol designed to simulate the metabolic demands of team sport. Ten female team-sport athletes participated in a randomised cross-over investigation. Upon completion of the protocol participants consumed 500ml of milk (MILK) or 500ml of an energy-matched carbohydrate (CHO) drink...
October 3, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28972203/injectable-%C3%AE-tcp-mcpm-cement-associated-with-mesoporous-silica-for-bone-regeneration-characterization-and-toxicity-evaluation
#17
Larissa S Mendes, Sybele Saska, Fernanda Coelho, Ticiana Sidorenko de Oliveira Capote, Raquel Mantuaneli Scarel-Caminaga, Reinaldo Marquetto, Raúl García Carrodeguas, Ana Maria Minarelli Gaspar, Miguel Angel Rodríguez
Calcium phosphate cements (CPC) have been widely investigated as bone graft substitutes due to its excellent self-setting ability, biocompatibility, osteoconductivity and moldability. In additional, mesoporous materials have also been studied as potential materials for application in medical devices due to their large surface area, which is capable of loading numerous biological molecules, besides being bioactive. In this study, bone β-TCP-MCPM-based injectable cement with mesoporous silica particles was synthesized and characterized in terms of their mechanical properties, microstructure, porosity, injectability, in vitro bioactivity and degradability; moreover, toxicity effects in CHO-K1 cells culture...
October 3, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28968113/oriented-enzyme-immobilization-at-the-oil-water-interface-enhances-catalytic-activity-and-recyclability-in-a-pickering-emulsion
#18
Jinghui Wang, Renliang Huang, Wei Qi, Rongxin Su, Zhimin He
Enzyme-loaded water-in-oil Pickering emulsion is a promising system for biphasic catalytic reactions. In this paper, we report on oriented enzyme immobilization at the oil/water interface in a Pickering emulsion, in which CHO-Janus silica nanoparticles (CHO-JNPs) are utilized as a stabilizer of the emulsion and support for the enzyme to enhance both catalytic activity and recyclability. The catalytic performance of this immobilized enzyme (lipase from Candida sp.) was evaluated by esterification of hexanoic acid and 1-hexanol in a water/heptane biphasic medium...
October 13, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28966520/epstein-barr-virus-associated-vesiculopapular-eruption-on-the-face-of-a-patient-with-natural-killer-t-cell-lymphoma
#19
Ji Soo Lim, Tae Min Kim, Kwang Hyun Cho
Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are characterized by the T-cell immunophenotype. Here, we report the first Korean case of EBV-associated vesiculopapular eruption on the face of a patient with natural killer (NK)/T cell lymphoma. A 32-year-old Korean man presented with a late adolescent-onset recurrent necrotic papulovesicles on his face...
October 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28944765/folate-receptor-targeted-nir-sensitive-polydopamine-nanoparticles-for-chemo-photothermal-cancer-therapy
#20
Hao Li, Zhen Jin, Sunghoon Cho, Mi Jeong Jeon, Van Du Nguyen, Jong-Oh Park, Sukho Park
We propose the use of folate-receptor-targeted, near-infrared-sensitive polydopamine nanoparticles (NPs) for chemo-photothermal cancer therapy as an enhanced type of drug-delivery system which can be synthesized by in situ polymerization and conjugation with folic acid. The NPs consist of a Fe3O4/Au core, coated polydopamine, conjugated folic acid, and loaded anti-cancer drug (doxorubicin). The proposed multifunctional NPs show many advantages for therapeutic applications such as good biocompatibility and easy bioconjugation...
October 20, 2017: Nanotechnology
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