keyword
MENU ▼
Read by QxMD icon Read
search

management of pulmonary embolism

keyword
https://www.readbyqxmd.com/read/29916427/role-of-closure-of-patent-foramen-ovale-in-cryptogenic-stroke-current-status
#1
REVIEW
B Sunil Abhishek, Anupam Bhambhani
Ischaemic stroke is among the leading causes of disability and death. Despite extensive vascular, cardiac and serological evaluations, the cause remains unknown in 20%-40% of patients. These are classified as cryptogenic stroke. Paradoxical embolism is one of the many causes of cryptogenic stroke. The term paradoxical embolism is used to describe an embolus of venous origin entering the systemic circulation through a patent foramen ovale (PFO), atrial septal defect (ASD), ventricular septal defect or extracardiac communication such as pulmonary arteriovenous malformation...
September 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/29914983/inhibition-of-the-cyclophilin-a-cd147-interaction-attenuates-right-ventricular-injury-and-dysfunction-after-acute-pulmonary-embolism-in-rats
#2
Guangdong Lu, Zhenyu Jia, Qingquan Zu, Jinxing Zhang, Linbo Zhao, Haibin Shi
Acute pulmonary embolism (APE)-induced inflammation contributes to cardiomyocyte injury and dysfunction in the right ventricle (RV) of the heart. The interactions of cyclophilin A with its ligand extracellular matrix metalloproteinase inducer (EMMPRIN or CD147) may be involved in this inflammatory process. To this end, here we induced APE by intravenous injections of microspheres in Sprague-Dawley rats. We found that after the APE, cyclophilin A, and CD147 levels increased synchronously in RV tissue following APE and peaked at 24 hours...
June 18, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29914908/prevalence-and-outcomes-of-incidental-imaging-findings-umbrella-review
#3
Jack W O'Sullivan, Tim Muntinga, Sam Grigg, John P A Ioannidis
OBJECTIVE: To provide an overview of the evidence on prevalence and outcomes of incidental imaging findings. DESIGN: Umbrella review of systematic reviews. DATA SOURCES: Searches of MEDLINE, EMBASE up to August 2017; screening of references in included papers. ELIGIBILITY CRITERIA: Criteria included systematic reviews and meta-analyses of observational studies that gave a prevalence of incidental abnormalities ("incidentalomas")...
June 18, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29911017/free-floating-right-heart-thrombus-with-acute-massive-pulmonary-embolism-a-case-report-and-review-of-the-literature
#4
Fida Charif, Mohamad Jihad Mansour, Righab Hamdan, Claudette Najjar, Pierre Nassar, Mohamad Issa, Elie Chammas, Mohamad Saab
Free-floating right heart thrombus (RHT) is an extreme medical emergency in the context of acute massive pulmonary embolism (PE). Despite the advances in early diagnosis, the management is still very debatable due to lack of consensus. We reported the case of a 66-year-old male, with a history of moderate renal dysfunction and dilated cardiomyopathy, who presented to the emergency department for acute dyspnea. His angiographic magnetic resonance imaging revealed bilateral extensive PE. Transthoracic echocardiography showed RHT with moderate right ventricular dysfunction and pulmonary hypertension...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29907418/long-term-experience-with-a-mandatory-clinical-decision-rule-and-mandatory-d-dimer-in-the-evaluation-of-suspected-pulmonary-embolism
#5
Guy W Soo Hoo, Emily Tsai, Sondra Vazirani, Zhaoping Li, Bruce M Barack, Carol C Wu
PURPOSE: This study evaluated the long-term effectiveness of mandatory assignment of both a clinical decision rule (CDR) and highly sensitive d-dimer in the evaluation of patients with suspected pulmonary embolism (PE). MATERIALS AND METHODS: Institutional guidelines with a CDR and highly sensitive d-dimer were embedded in an order entry menu with mandatory assignment of key components before ordering a CT pulmonary angiogram (CTPA). Data were retrospectively extracted from the electronic health record...
June 12, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29906522/evaluation-of-venous-thromboembolic-complications-in-patients-operated-on-for-pelvic-fracture
#6
Candice Ostrowka, Stéphanie Bonhomme, Pomme Jouffroy, Guillaume Riouallon
INTRODUCTION: Fractures of the pelvis (acetabulum and pelvic ring) are complex in both radiological diagnosis and therapeutic management. They show high risk of thrombosis, with variable rates of venous thromboembolic complications in the literature, ranging from 10% to 50%, with 0.5-10% risk of fatal pulmonary embolism. The objective of the present study was to determine the rate of venous thromboembolic events in a consecutive cohort of pelvic fracture and to attempt to identify thromboembolic risk factors in this population...
June 12, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29901460/mechanical-circulatory-devices-in-acute-heart-failure
#7
Marc Pineton de Chambrun, Nicolas Bréchot, Alain Combes
PURPOSE OF REVIEW: Temporary circulatory support (TCS) with short-term mechanical circulatory support (MCS) devices is increasingly used as a salvage therapy for patients with refractory cardiogenic shock. This article provides an overview of current devices, their indications and management, and discusses results of recent case series and trials. RECENT FINDINGS: Percutaneous active MCS devices (Impella, TandemHeart…) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) are utilized as a bridge to 'decision' that includes weaning after cardiac function recovery, transplantation, long-term MCS and withdrawal in case of futility...
June 8, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29898978/british-thoracic-society-guideline-for-the-initial-outpatient-management-of-pulmonary-embolism-pe
#8
S G E Howard Luke, Barden Steven, Condliffe Robin, Connolly Vincent, W H Davies Christopher, Donaldson James, Everett Bernard, Free Catherine, Horner Daniel, Hunter Laura, Kaler Jasvinder, Nelson-Piercy Catherine, O'Dowd Emma, Patel Raj, Preston Wendy, Sheares Karen, Tait Campbell
No abstract text is available yet for this article.
July 2018: Thorax
https://www.readbyqxmd.com/read/29898202/association-of-perioperative-red-blood-cell-transfusions-with-venous-thromboembolism-in-a-north-american-registry
#9
Ruchika Goel, Eshan U Patel, Melissa M Cushing, Steven M Frank, Paul M Ness, Clifford M Takemoto, Ljiljana V Vasovic, Sujit Sheth, Marianne E Nellis, Beth Shaz, Aaron A R Tobian
Importance: Increasing evidence supports the role of red blood cells (RBCs) in physiological hemostasis and pathologic thrombosis. Red blood cells are commonly transfused in the perioperative period; however, their association with postoperative thrombotic events remains unclear. Objective: To examine the association between perioperative RBC transfusions and postoperative venous thromboembolism (VTE) within 30 days of surgery. Design, Setting, and Participants: This analysis used prospectively collected registry data from the American College of Surgery National Surgical Quality Improvement Program (ACS-NSQIP) database, a validated registry of 525 teaching and nonteaching hospitals in North America...
June 13, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29895399/a-systematic-review-and-meta-analysis-of-thrombotic-events-following-endovenous-thermal-ablation-of-the-great-saphenous-vein
#10
REVIEW
Donagh A Healy, Shiori Kimura, David Power, Abubaker Elhaj, Yasser Abdeldaim, Keith S Cross, Gerard T McGreal, Paul E Burke, Tony Moloney, Brian J Manning, Eamon G Kavanagh
OBJECTIVES: A systematic review and meta-analysis was performed to determine the incidence of thrombotic events following great saphenous vein (GSV) endovenous thermal ablation (EVTA). METHODS: MEDLINE, Embase and conference abstracts were searched. Eligible studies were randomised controlled trials and case series that included at least 100 patients who underwent GSV EVTA (laser ablation or radiofrequency ablation [RFA]) with duplex ultrasound (DUS) within 30 days...
June 9, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29893185/early-thrombolytic-failure-in-a-patient-with-massive-pulmonary-embolism-combined-with-multiple-organ-dysfunction-syndrome-what-next
#11
Furong Liu, Song Yang, Weishuo Liu, Baiyun Tang, Wenbo Zhang, Cheng Zhang, Wenwei Liao, Anbin Hu
Carbon monoxide (CO) poisoning, the most frequent type of poisoning, alters hemodynamics and creates tissue hypoxia that ultimately leads to thromboembolism. We herein describe a previously healthy 17-year-old male patient who developed acute CO poisoning while bathing in the same room as a gas heater. He was first treated with urokinase thrombolytic therapy at a local hospital, which proved ineffective. The patient was admitted to our hospital with unstable circulation and was diagnosed with massive pulmonary embolism combined with multiple organ dysfunction syndrome...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29880507/abnormal-ventilation-perfusion-scan-is-associated-with-pulmonary-hypertension-in-sickle-cell-adults
#12
Alem Mehari, Norris Igbineweka, Darlene Allen, Jim Nichols, Swee Lay Thein, Nargues A Weir
Pulmonary hypertension (PH) in adults with sickle cell disease (SCD) is associated with early mortality. Chronic thromboembolic pulmonary hypertension (CTEPH) is an important complication and contributor to PH in SCD, but likely underappreciated. Guidelines recommend ventilation-perfusion scintigraphy (V/Q) as imaging modality of choice to exclude CTEPH. Data on V/Q are limited in SCD. Objective: To compare the performance of V/Q with computed tomography pulmonary angiography (CTPA) and to report clinical outcomes associated with abnormal V/Q...
June 7, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29872242/novel-anticoagulant-treatment-for-pulmonary-embolism-with-direct-oral-anticoagulants-phase-3-trials-and-clinical-practice
#13
REVIEW
Cécile Tromeur, Liselotte M van der Pol, Albert T A Mairuhu, Christophe Leroyer, Francis Couturaud, Menno V Huisman, Frederikus A Klok
Anticoagulant therapy is the cornerstone of therapeutic management in acute venous thromboembolism (VTE), consisting of pulmonary embolism and deep vein thrombosis. Direct oral anticoagulants (DOACs) have become the standard of care because of their good safety profile and ease of use in clinical practice. Indeed, phase 3 randomized trials (AMPLIFY, EINSTEIN, RECOVER, and HOKUSAI studies) showed that DOACs provided a similar efficacy and a better safety than conventional treatment with parenteral heparin with overlapping loading dose of vitamin K antagonists in acute VTE therapeutic management...
June 2018: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/29859153/collaborative-management-of-missile-injury-to-right-ventricle-and-subsequent-pulmonary-embolization
#14
Agustin Sibona, Jason C Smith, Daniel P Srikureja, Rahul Sharma, Carin Mascetti, Anees J Razzouk, David G Rabkin
Pulmonary embolization of a missile is a rare phenomenon. Localization after embolization can be confounding and there is no consensus on management. We report a case of a gunshot wound to the chest with preoperative and initial intraoperative imaging localizing the bullet to the right ventricle but a negative intraoperative exploration of the right-sided cardiac chambers. Intraoperative fluoroscopy allowed for immediate localization of the bullet to the hilum of the left lung with subsequent endovascular retrieval...
May 30, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29850272/unique-ecg-findings-in-acute-pulmonary-embolism-ste-with-reciprocal-changes-and-pathologic-q-wave
#15
Amanda Grant-Orser, Brennan Ballantyne, Wael Haddara
A 68-year-old male presented to the emergency department with retrosternal chest pain, presyncope, and then a pulseless electrical activity cardiac arrest. An ECG prior to his arrest revealed ST elevations in leads V1-V3, Q waves in lead V2, and reciprocal ST depressions in the lateral and inferior leads. He received thrombolytic therapy for a presumptive diagnosis of ST elevation myocardial infarction. Return of spontaneous circulation was achieved and he underwent a coronary angiogram. No critical disease was found and his left ventriculogram showed normal contraction...
2018: Case Reports in Critical Care
https://www.readbyqxmd.com/read/29850139/early-surgical-treatment-in-patients-with-pulmonary-embolism-and-thrombus-in-transit
#16
Francisco Galeano-Valle, Pablo Demelo-Rodríguez, Irene García-Fernández-Bravo, Hugo Rodríguez-Abella, Ángela Irabien-Ortiz, Ramón Fortuny-Ribas, Jorge Del Toro-Cervera
Background: Floating right heart thrombi (RHT) are in transit from the legs to the pulmonary arteries and thus are a severe form of venous thromboembolism (VTE), with a high early mortality rate without treatment. There is a lack of evidence-based recommendations for its management. The objective of this study is to describe our experience in the surgical management of thrombus-in-transit and pulmonary embolism (PE) in a tertiary hospital. Methods: We recruited four patients with thrombus-in-transit and PE treated with early surgical embolectomy and anticoagulation...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29849348/successful-point-of-care-ultrasound-guided-treatment-of-submassive-pulmonary-embolism
#17
Samantha J Myers, Thomas E Kelly, Jeffrey R Stowell
Pulmonary embolism is associated with significant mortality and impaired long-term functional outcomes. Timely identification and treatment is crucial for successful management. Unfortunately, prompt diagnosis can be challenging in patients without overt signs of cardiovascular compromise. Point-of-care cardiac ultrasound (POCCUS) can be used to identify signs of acute pulmonary embolism, risk stratify patients for adverse outcomes and assess response to therapy. This report describes a patient with submassive pulmonary embolism and evidence of acute right ventricular strain on POCCUS successfully treated with thrombolytic therapy...
November 2017: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/29848540/pulmonary-embolism-and-infarction-with-a-paradoxical-thrombus-visualised-in-both-atria
#18
Hamza Zafar, Lisa Anderson, Andrew T Cox, Rachel Bastiaenen
A 59-year-old woman presented with a sudden onset of breathlessness and chest pain. An echocardiography and CT scan showed pulmonary embolism and infarction with a paradoxical thrombus visualised in both atria. For haemodynamically stable patients, the optimal management strategy is poorly defined. Three main strategies were considered: surgical thrombectomy, thrombolysis and anticoagulation. Surgery with reversal of anticoagulation may lead to further coagulation and increased risk of bleeding complications...
May 30, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29846298/a-case-series-of-outcomes-in-isolated-subsegmental-pulmonary-embolism-on-ventilation-perfusion-imaging
#19
Amy Mallorie, Kenneth Chan, Stefanos Ioannidis, Matthew Stubbs, Shaunak Navalkissoor, Thomas Wagner
OBJECTIVES: The risk of recurrent venous thromboembolic disease and the management of patients with isolated subsegmental pulmonary embolism (SSPE) remain unclear. We sought to assess the long-term clinical outcome of patients with isolated SSPE demonstrated by isolated subsegmental mismatch found on ventilation/perfusion (V/Q) scans. PATIENTS AND METHODS: We performed a retrospective observational study of 1300 consecutive patients with suspected pulmonary embolism who underwent index V/Q single-photon emission computed tomography between 2012 and 2013...
May 25, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29843174/reperfusion-treatment-for-acute-pulmonary-embolism
#20
Rolf P Engelberger, Nils Kucher
Due to the manifold treatment options for the management of acute pulmonary embolism, state-of-the-art management requires risk stratification for choosing the adapted treatment for each patient. Reperfusion therapy is an integral part of therapy for patients with pulmonary embolism at high risk for mortality, but its role in patients with intermediate risk pulmonary embolism is more debated. The largest amount of evidence exists for systemic thrombolysis, which is an efficient therapy, but at the prize of an increased bleeding risk...
May 2018: Hämostaseologie
keyword
keyword
97685
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"