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https://www.readbyqxmd.com/read/28530082/-cervical-cancer-in-israel-2016-facts-insights-and-thoughts-for-the-future
#1
REVIEW
Menahem Fisher, Eduardo Schejter, Ido Solt, Gad Renart
The natural history of precancerous lesions and cervical cancer in Israeli women differs from that reported in the world. In 2011, 244 women were diagnosed in Israel with invasive cervical cancer, with the mortality of 79 women. The incidence of cervical cancer in Israel is about 5 new cases per year per 100,000 women (5.4 Jewish, 3.2 Arab). This figure is very low compared with statistics presented in other countries and has not changed over the last decades. The vast majority of Israeli women were diagnosed due to symptoms and not following Pap smear screening...
September 2016: Harefuah
https://www.readbyqxmd.com/read/28530060/-the-truth-about-the-ringworm-affair
#2
REVIEW
Aya Bar Oz
Ringworm of the scalp (Tinea Capitis), a fungal skin ailment that appears on the scalp, was treated until the early sixties by radiation therapy. It was discovered during the seventies that radiation treatment for ringworm may be associated with a higher risk of cancerous and benign tumors in the head and neck area for patients undergoing treatment. In 1995, Israel enacted a law to compensate ringworm irradiation patients which provided monetary compensation for those who were treated between 1946 and 1960...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28520658/age-group-and-gender-differences-in-stroke-knowledge-in-an-israeli-jewish-adult-population
#3
Semyon Melnikov, Michal Itzhaki, Silvia Koton
BACKGROUND: Stroke is a leading cause of long-term disability and the fifth leading cause of death in Israel. Knowledge of stroke warning signs has been linked to early seeking of medical help. Little is known about knowledge of stroke warning signs in Israeli Jewish adults. METHODS: Stroke knowledge was examined among Jewish Israeli adults. Using a structured questionnaire, registered nurses interviewed a convenience sample of the respondents, 18 years or older, with no stroke history...
May 17, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28514134/-well-child-visits-regarding-growth-and-development-of-infants-a-cross-cultural-comparison
#4
Yana Shraga, Orly Sarid, Julie Cwikel, Haim Reuveni
AIMS: 1. To examine the rate of WCV among mothers in four ethno-cultural groups: native-born Jewish, Bedouin and immigrants from the Former Soviet Union (FSU) and Ethiopia; 2. to test the relationship between WCV in the first and second year of the infant's life; 3. to assess the effect of sociodemographic variables on WCV. BACKGROUND: Consistent infant well-child visits (WCV) have been found to be related to better health status and a decrease in visits to the emergency room and hospitalizations...
July 2016: Harefuah
https://www.readbyqxmd.com/read/28513215/presence-of-air-trapping-and-mosaic-attenuation-on-chest-ct-predicts-survival-in-chronic-hypersensitivity-pneumonitis
#5
Jonathan H Chung, Xi Zhan, Mengshu Cao, Tilman L Koelsch, Diana C Gomez, Kevin K Brown, David A Lynch, Gloria Russell, Evans R Fernández Pérez
RATIONALE: Significant heterogeneity of computed tomography (CT) presentation exists within chronic hypersensitivity pneumonitis (CHP). There is limited data aimed at delineating the prognostic value of specific CT features, distribution, and patterns in CHP. OBJECTIVES: To examine whether the presence of CT mosaic attenuation and air-trapping, and the distribution or patterns of fibrosis impact survival in subjects with CHP. METHODS: From the National Jewish Health interstitial lung disease research database, we retrospectively identified 110 consecutively enrolled well-characterized biopsy-proven CHP adult subjects between 1982 and 2015...
May 17, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28511177/familial-hyperkalemia-and-hypertension-fhht-and-klhl3-description-of-a-family-with-a-new-recessive-mutation-s553l-compared-to-a-family-with-a-dominant-mutation-q309r-with-analysis-of-urinary-sodium-chloride-cotransporter
#6
Orit Kliuk-Ben Bassat, Vered Carmon, Aaron Hanukoglu, Liat Ganon, Eias Massalha, Eliezer J Holtzman, Zvi Farfel, Haim Mayan
BACKGROUND: Familial hyperkalemia and hypertension (FHHt) is an inherited disorder manifested by hyperkalemia and hypertension. The following four causative genes were identified: WNK1, WNK4, CUL3, and KLHL3. For the first 3 genes, inheritance is autosomal dominant. For KLHL3, inheritance is mostly dominant. A few cases with autosomal recessive disease were described. The mechanism of these 2 modes of inheritance is not clear. In the recessive form, the phenotype of heterozygotes is not well described...
May 17, 2017: Nephron
https://www.readbyqxmd.com/read/28502252/differential-analysis-of-mutations-in-the-jewish-population-and-their-implications-for-diseases
#7
Yaron Einhorn, Daphna Weissglas-Volkov, Shai Carmi, Harry Ostrer, Eitan Friedman, Noam Shomron
Sequencing large cohorts of ethnically homogeneous individuals yields genetic insights with implications for the entire population rather than a single individual. In order to evaluate the genetic basis of certain diseases encountered at high frequency in the Ashkenazi Jewish population (AJP), as well as to improve variant annotation among the AJP, we examined the entire exome, focusing on specific genes with known clinical implications in 128 Ashkenazi Jews and compared these data to other non-Jewish populations (European, African, South Asian and East Asian)...
May 15, 2017: Genetics Research
https://www.readbyqxmd.com/read/28497706/striking-ethnic-variations-in-the-epidemiology-of-chlamydia-trachomatis-in-haifa-district-israel-throughout-the-years-2001-2015
#8
Khalaf Kridin, Mogher Khamaisi, Shmuel Rishpon, Rami Grifat
Our objectives were to examine trends in the incidence of chlamydia over an extended period and compare the epidemiology of the infection between two distinct ethnic groups in Israel: Jews and Arabs. We examined the incidence rate of Chlamydia trachomatis infection among residents of Haifa District, northern Israel from 2001 to 2015, by reviewing archives of the Department of Epidemiology, Ministry of Health. Notified cases were stratified by age group, gender, and ethnic group. The overall incidence rate of Chlamydia was 10...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28495237/multigene-panels-in-ashkenazi-jewish-patients-yield-high-rates-of-actionable-mutations-in-multiple-non-brca-cancer-associated-genes
#9
Melissa K Frey, Gabriella Sandler, Rachel Sobolev, Sarah H Kim, Rachelle Chambers, Rebecca Y Bassett, Jessica Martineau, Katherine J Sapra, Leslie Boyd, John P Curtin, Bhavana Pothuri, Stephanie V Blank
OBJECTIVE: To evaluate the results of multigene panel testing among Ashkenazi Jewish compared with non-Ashkenazi Jewish patients. METHODS: We reviewed the medical records for all patients who underwent multigene panel testing and targeted BRCA1/2 testing at a single institution between 6/2013-1/2015. Clinical actionability for identified pathogenic mutations was characterized based on the National Comprehensive Cancer Network (NCCN) guidelines and consensus statements and expert opinion for genes not addressed by these guidelines...
May 8, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28495138/effect-of-ethnic-origin-and-gender-on-the-clinical-manifestations-of-myasthenia-gravis-among-the-jewish-population-in-israel
#10
Ali Asmail, Anat Kesler, Vivian E Drory, Hadar Kolb, Arnon Karni
Reports on patients with myasthenia gravis (MG) of different ethnic origins demonstrated differences in weakness distribution and serological results. We studied MG characteristics in a cohort of Ashkenazi (ASH) and non-Ashkenazi (NASH) Jewish origin according to their ethnic origins and gender. The frequency of age of MG onset was distributed in a bi-modal fashion in the female patients and increased gradually over time, with a peak around 70years of age in the male patients. Ocular MG was more frequent in males and ASH patients...
June 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28495106/israel-health-and-beyond
#11
REVIEW
Karl Skorecki, Richard Horton
The principle that global human identity and dignity supersede other values is a broadly accepted conviction that guides practice and policies in the realm of human health in most of the world. An assessment of the level of success that Israel has achieved in health, in the face of formidable challenges, including rapid population growth, diverse and often divided ethnic affiliations, and existential security threats, leads us to propose that extension of this principle of global human identity and dignity, together with the objective of a decent society, as overriding values beyond health to other domains of human endeavour within Israel and in its relations with neighbouring peoples, represents an entirely achievable imperative...
May 5, 2017: Lancet
https://www.readbyqxmd.com/read/28492035/the-german-experiment-health-care-without-female-or-jewish-doctors
#12
Alexa R Shipman
Jewish and female doctors were not allowed to practice medicine in Germany during Hitler's rule from 1933 to 1945. Data about the consequences of this on the health service are difficult to come by, but what information can be gathered demonstrates a detrimental effect on the nation's health. These data, however, must be interpreted with consideration to the morbidity and mortality from violence, death camps, slave labor, and the privations of war. The article summarizes the history of German health care during this period and also compares Germany to other nations at that time...
March 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28492025/validation-studies-of-outcome-measures-in-pemphigus
#13
REVIEW
Sarah Hanna, Minhee Kim, Dedee F Murrell
Pemphigus is a group of rare and potentially fatal autoimmune blistering diseases that are associated with auto-antibodies that target intercellular adhesion molecules. Incidence of pemphigus varies among populations, with the lowest incidence in Switzerland and Finland at 0.6-0.76 per million per year and the highest in Jewish communities at 16.1-32 per million per year. Pemphigus is associated with devastating morbidity and despite advancements in our understanding of the disease and a widening array of therapeutic options, no cure exists...
December 2016: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28490612/pathology-update-to-the-manchester-scoring-system-based-on-testing-in-over-4000-families
#14
D Gareth Evans, Elaine F Harkness, Inga Plaskocinska, Andrew J Wallace, Tara Clancy, Emma R Woodward, Tony A Howell, Marc Tischkowitz, Fiona Lalloo
BACKGROUND: While the requirement for thresholds for testing for mutations in BRCA1/2 is being questioned, they are likely to remain for individuals unaffected by a relevant cancer. It is still useful to provide pretesting likelihoods, but models need to take into account tumour pathology. METHODS: The Manchester Scoring System (MSS) is a well-used, simple, paper-based model for assessing carrier probability that already incorporates pathology data. We have used mutation testing data from 4115 unrelated samples from affected non-Jewish individuals alongside tumour pathology to further refine the scoring system...
May 10, 2017: Journal of Medical Genetics
https://www.readbyqxmd.com/read/28486082/bereavement-of-israeli-arab-muslim-widows-determinants-of-adjustment-and-supporting-attributes
#15
Hend Yasien-Esmael, Yohanan Eshel, Simon Shimshon Rubin
Cultural-specific determinants of coping with widowhood were investigated by the Two-Track-Bereavement Model. Participants were 93 middle aged and middle class Israeli Arab Muslim widows. Factor analysis emitted four factors of adjusting to widowhood. The suffering and resilience factors and the total scale score were consistently correlated with personality attributes, whereas demographics were associated mainly with the suffering factor and the total scale score. The factors differed from the factors characteristic of Israeli Jewish bereaved, which emphasize the need to examine models of bereavement in cross-cultural perspective and to account for the interaction of cultural effects with psychological processes...
May 9, 2017: Death Studies
https://www.readbyqxmd.com/read/28481778/the-relationship-between-body-image-gender-subjective-norms-and-the-decision-to-undergo-preventive-mastectomy-among-arab-and-jewish-brca-carriers
#16
Majeda Kardosh, Yoram Bar-Tal, Sivia Barnoy
BACKGROUND: Carriers for a mutation in BRCA1/2 genes have a high, lifelong risk for developing breast cancer. Preventive mastectomy is considered an effective risk reduction surgery. Many factors might affect the decision to undergo preventive mastectomy, including culture, perceived body image after mastectomy and important others opinion. OBJECTIVE: The aim of this study is to evaluate BRCA mutation carriers' decision to undergo preventive mastectomy and the relationship between culture, gender, body image, and the decision...
May 5, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28480668/osteoporosis-a-future-public-health-problem-for-israel-medical-and-legal-obligations
#17
George M Weisz
Starvation in early life can lead to premature metabolic syndrome and bone demineralization. Osteoporosis in the Jewish population may not yet be a recognized syndrome, but the harsh conditions to which Holocaust survivors were exposed may have increased the incidence of the condition. Immigrants and refugees who came to Israel from East Africa and Yemen - whether decades ago or more recently - may have been at increased risk of under-nutrition during pregnancy, affecting both the mother and consequently the offspring...
April 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28473427/erg-and-oct-findings-of-a-patient-with-a-clinical-diagnosis-of-occult-macular-dystrophy-in-a-patient-of-ashkenazi-jewish-descent-associated-with-a-novel-mutation-in-the-gene-encoding-rp1l1
#18
Norman Saffra, Carly Jane Seidman, Aleksandr Rakhamimov, Stephen H Tsang
A 57-year-old man with a past medical history of diabetes presented for consultation with a several year history of slowly progressive vision loss in both eyes, which continued to deteriorate over 7 years of follow-up. Multimodal imaging was performed and was significant for the following: on spectral domain optical coherence tomography, a gap lesion was present in the ellipsoid layer, beneath the umbo, as well as subtle macular changes on auto fluorescence imaging. Multifocal electroretinography was performed and was abnormal, and a clinical diagnosis of occult macular dystrophy was made...
May 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28472603/young-women-s-perceptions-regarding-communication-with-healthcare-providers-about-breast-cancer-risk-and-prevention
#19
Natasha Buchanan Lunsford, Karena F Sapsis, Betsy Smither, Jennifer Reynolds, Ben Wilburn, Temeika Fairley
BACKGROUND: Women younger than 45 years old have lower rates of breast cancer, but higher risk of recurrence and mortality after a cancer diagnosis. African American women are at risk for early onset and increased mortality; Ashkenazi Jewish women are at risk for genetic mutations leading to breast and ovarian cancer. Although younger women are encouraged to talk to doctors about their family history, little is known about these discussions. MATERIALS AND METHODS: In 2015, 167 women aged 18-44 years participated in 20 focus groups segmented by geographic location, age, race/ethnicity, and family history of breast and ovarian cancer...
May 4, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28471621/automated-breast-volumetric-sonography-compared-with-magnetic-resonance-imaging-in-jewish-brca-1-2-mutation-carriers
#20
Osnat Halshtok Neiman, Zippy Erlich, Eitan Friedman, Arie Rundstein, Anat Shalmon, Yael Servadio, Miri Sklair Levy
BACKGROUND: Automated breast volumetric sonography (ABVS) is a new technology with various possible applications. OBJECTIVES: To compare ABVS and breast magnetic resonance imaging (MRI) in the surveillance of women with BRCA1/2 gene mutation carriers. METHODS: We conducted a prospective study in Jewish female BRCA1/2 mutation carriers who underwent breast MRI and ABVS. The results of both exams performed 6 months apart or less, and relevant clinical data, were reviewed...
October 2016: Israel Medical Association Journal: IMAJ
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