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high-resolution MRI

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https://www.readbyqxmd.com/read/28328939/multimodal-mr-imaging-reveals-large-scale-structural-and-functional-connectivity-changes-in-profound-early-blindness
#1
Corinna M Bauer, Gabriella V Hirsch, Lauren Zajac, Bang-Bon Koo, Olivier Collignon, Lotfi B Merabet
In the setting of profound ocular blindness, numerous lines of evidence demonstrate the existence of dramatic anatomical and functional changes within the brain. However, previous studies based on a variety of distinct measures have often provided inconsistent findings. To help reconcile this issue, we used a multimodal magnetic resonance (MR)-based imaging approach to provide complementary structural and functional information regarding this neuroplastic reorganization. This included gray matter structural morphometry, high angular resolution diffusion imaging (HARDI) of white matter connectivity and integrity, and resting state functional connectivity MRI (rsfcMRI) analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28328530/imaging-methods-for-bone-mass-evaluation-during-childhood-and-adolescence-an-update
#2
Isabela Leite Pezzuti, Adriana Maria Kakehasi, Maria Tereza Filgueiras, Juliana Albano de Guimarães, Isabela Alves Campos de Lacerda, Ivani Novato Silva
The objective of the work was to prepare an update on imaging methods for bone evaluation during childhood and adolescence. The text was based on original and review articles on imaging methods for clinical evaluation of bone mass in children and adolescents up to 20 years old. They were selected from BIREME and PUBMED by means of the following keywords: bone density; osteoporosis/diagnosis; densitometry; tomography; ultrasonography; magnetic resonance imaging; and radiogrammetry and published in Portuguese or English, in the last 10 years (2006-2016)...
March 22, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28324693/cortical-complexity-in-bipolar-disorder-applying-a-spherical-harmonics-approach
#3
Igor Nenadic, Rachel A Yotter, Maren Dietzek, Kerstin Langbein, Heinrich Sauer, Christian Gaser
Recent studies using surface-based morphometry of structural magnetic resonance imaging data have suggested that some changes in bipolar disorder (BP) might be neurodevelopmental in origin. We applied a novel analysis of cortical complexity based on fractal dimensions in high-resolution structural MRI scans of 18 bipolar disorder patients and 26 healthy controls. Our region-of-interest based analysis revealed increases in fractal dimensions (in patients relative to controls) in left lateral orbitofrontal cortex and right precuneus, and decreases in right caudal middle frontal, entorhinal cortex, and right pars orbitalis, and left fusiform and posterior cingulate cortices...
February 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28321484/rhabdomyolysis-resulting-in-concurrent-horner-s-syndrome-and-brachial-plexopathy-a-case-report
#4
Susan C Lee, Christian Geannette, Scott W Wolfe, Joseph H Feinberg, Darryl B Sneag
This case report describes a 29-year-old male who presented with immediate onset of Horner's syndrome and ipsilateral brachial plexopathy after sleeping with his arm dangling outside a car window for 8 h. Outside workup and imaging revealed rhabdomyolysis of the left neck musculature. Subsequent electrodiagnostic testing and high-resolution brachial plexus magnetic resonance imaging at the authors' institution attributed the Horner's syndrome and concurrent brachial plexopathy to rhabdomyolysis of the longus colli and scalene musculature, which had compressed-and consequently scar tethered-the cervical sympathetic trunk and brachial plexus...
March 20, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28320412/high-resolution-hemodynamic-profiling-of-murine-arteriovenous-fistula-using-magnetic-resonance-imaging-and-computational-fluid-dynamics
#5
Daniel Pike, Yan-Ting Shiu, Maheshika Somarathna, Lingling Guo, Tatyana Isayeva, John Totenhagen, Timmy Lee
BACKGROUND: Arteriovenous fistula (AVF) maturation failure remains a major cause of morbidity and mortality in hemodialysis patients. The two major etiologies of AVF maturation failure are early neointimal hyperplasia development and persistent inadequate outward remodeling. Although hemodynamic changes following AVF creation may impact AVF remodeling and contribute to neointimal hyperplasia development and impaired outward remodeling, detailed AVF hemodynamics are not yet fully known...
March 20, 2017: Theoretical Biology & Medical Modelling
https://www.readbyqxmd.com/read/28319687/effects-of-subclinical-depression-anxiety-and-somatization-on-brain-structure-in-healthy-subjects
#6
Bianca Besteher, Christian Gaser, Kerstin Langbein, Maren Dietzek, Heinrich Sauer, Igor Nenadić
BACKGROUND: Dimensional approaches in highly prevalent psychiatric disorders like depression or anxiety could lead to a better understanding of pathogenesis and advantages in early detection and prevention. In an effort to better understand associations of brain structural variation across the depression/anxiety spectra, we investigated minor subclinical symptoms in a non-clinical healthy population. METHODS: We studied 177 healthy subjects from the community, who underwent high-resolution T1-weighted 3T MRI and completed the symptom-checklist-90 (SCL-90-R)...
March 16, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28314241/characterizing-articulation-in-apraxic-speech-using-real-time-magnetic-resonance-imaging
#7
Christina Hagedorn, Michael Proctor, Louis Goldstein, Stephen M Wilson, Bruce Miller, Maria Luisa Gorno-Tempini, Shrikanth S Narayanan
Purpose: Real-time magnetic resonance imaging (MRI) and accompanying analytical methods are shown to capture and quantify salient aspects of apraxic speech, substantiating and expanding upon evidence provided by clinical observation and acoustic and kinematic data. Analysis of apraxic speech errors within a dynamic systems framework is provided and the nature of pathomechanisms of apraxic speech discussed. Method: One adult male speaker with apraxia of speech was imaged using real-time MRI while producing spontaneous speech, repeated naming tasks, and self-paced repetition of word pairs designed to elicit speech errors...
March 17, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28304232/a-systematic-evaluation-of-intraoperative-white-matter-tract-shift-in-pediatric-epilepsy-surgery-using-high-field-mri-and-probabilistic-high-angular-resolution-diffusion-imaging-tractography
#8
Joseph Yuan-Mou Yang, Richard Beare, Marc L Seal, A Simon Harvey, Vicki A Anderson, Wirginia J Maixner
OBJECTIVE Characterization of intraoperative white matter tract (WMT) shift has the potential to compensate for neuronavigation inaccuracies using preoperative brain imaging. This study aimed to quantify and characterize intraoperative WMT shift from the global hemispheric to the regional tract-based scale and to investigate the impact of intraoperative factors (IOFs). METHODS High angular resolution diffusion imaging (HARDI) diffusion-weighted data were acquired over 5 consecutive perioperative time points (MR1 to MR5) in 16 epilepsy patients (8 male; mean age 9...
March 17, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28304220/high-resolution-magnetic-resonance-imaging-of-carotid-atherosclerotic-plaques-a-correlation-study-with-histopathology
#9
Zhangyong Xia, Hua Yang, Xiaochun Yuan, Jiyue Wang, Shigang Zhang, Liyong Zhang, Yang Qu, Jun Chen, Liqun Jiao, Le-Xin Wang, Yifeng Du
BACKGROUND: This study aimed to utilize high-resolution magnetic resonance imaging (MRI) to investigate the characteristics of stable and vulnerable carotid arteriosclerotic plaques, with correlations to histopathological findings. PATIENTS AND METHODS: High-resolution MRI was performed in 817 patients, using three-dimensional magnetic resonance angiography. Plaque composition was evaluated by measuring the areas occupied by calcification, a lipid-rich necrotic core, intra-plaque haemorrhage, and fibrous cap rupture...
March 17, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28303917/reduced-regional-grey-matter-volumes-in-pediatric-obstructive-sleep-apnea
#10
Mona F Philby, Paul M Macey, Richard A Ma, Rajesh Kumar, David Gozal, Leila Kheirandish-Gozal
Pediatric OSA is associated with cognitive risk. Since adult OSA manifests MRI evidence of brain injury, and animal models lead to regional neuronal losses, pediatric OSA patients may also be affected. We assessed the presence of neuronal injury, measured as regional grey matter volume, in 16 OSA children (8 male, 8.1 ± 2.2 years, AHI:11.1 ± 5.9 events/hr), and 200 control subjects (84 male, 8.2 ± 2.0 years), 191 of whom were from the NIH-Pediatric MRI database. High resolution T1-weighted whole-brain images were assessed between groups with voxel-based morphometry, using ANCOVA (covariates, age and gender; family-wise error correction, P < 0...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28303611/improving-left-ventricular-segmentation-in-four-dimensional-flow-mri-using-intramodality-image-registration-for-cardiac-blood-flow-analysis
#11
Vikas Gupta, Mariana Bustamante, Alexandru Fredriksson, Carl-Johan Carlhäll, Tino Ebbers
PURPOSE: Assessment of blood flow in the left ventricle using four-dimensional flow MRI requires accurate left ventricle segmentation that is often hampered by the low contrast between blood and the myocardium. The purpose of this work is to improve left-ventricular segmentation in four-dimensional flow MRI for reliable blood flow analysis. METHOD: The left ventricle segmentations are first obtained using morphological cine-MRI with better in-plane resolution and contrast, and then aligned to four-dimensional flow MRI data...
March 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28302035/translational-multimodality-neuroimaging
#12
Sushil K Sharma
Recently high-resolution, noninvasive, multimodality in-vivo molecular imaging with PET, SPECT, CT and MRI, employing fusion algorithms has revolutionized personalized medicine. However, specific radiopharmaceuticals (RPs) for the accurate diagnosis and effective treatment of progressive neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, drug addiction, and other cognitive impairments still remain in developmental phase. Currently, multimodality fusion neuroimaging is utilized for the determination of: pharmacokinetics and pre-clinical development of radiopharmaceuticals (RPs); in-vivo monitoring of stem cell transplantation therapy; nicotinic acetylcholine receptors (nAChRs) investigations; and regional cerebral blood flow and glucose metabolism in cognitively-impaired subjects employing noninvasive microPET and nano-SPECT imaging...
March 15, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28298947/glomus-vagale-tumour-can-it-be-diagnosed-only-on-sonography
#13
Shuchi Bhatt, Pooja Verma, Neha Meena, Anupama Tandon, Nadeem Tanveer, Divya Bansal
Vagal paragangliomas are rare benign tumors accounting for only 3% of head and neck paragangliomas and arise from vagal ganglions, predominately the nodose ganglion in the carotid sheath. Imaging plays an important role in their diagnosis, differentiation from more common lesions presenting in the carotid space, and management. MRI is the method of choice for investigation when paragangliomas are clinically suspected. The typical salt-and-pepper appearance in T1-weighted images is well known but not specific to paragangliomas...
March 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28296979/feasibility-of-assessing-bone-matrix-and-mineral-properties-in-vivo-by-combined-solid-state-1h-and-31p-mri
#14
Xia Zhao, Hee Kwon Song, Alan C Seifert, Cheng Li, Felix W Wehrli
PURPOSE: To develop and evaluate an integrated imaging protocol for bone water and phosphorus quantification in vivo by solid-state 1H and 31P MRI. MATERIALS AND METHODS: All studies were HIPAA-compliant and were performed with institutional review board approval and written informed consent. Proton (1H) ultra-short echo-time (UTE) and phosphorus (31P) zero echo-time (ZTE) sequences were designed and implemented on a 3 T clinical MR scanner to quantify bone water and mineral in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28295563/in-vivo-mri-of-the-human-finger-at-7-t
#15
Elmar Laistler, Barbara Dymerska, Jürgen Sieg, Sigrun Goluch, Roberta Frass-Kriegl, Andre Kuehne, Ewald Moser
PURPOSE: To demonstrate a dedicated setup for ultrahigh resolution MR imaging of the human finger in vivo. METHODS: A radiofrequency coil was designed for optimized signal homogeneity and sensitivity in the finger at ultrahigh magnetic field strength (7 T), providing high measurement sensitivity. Imaging sequences (2D turbo-spin echo (TSE) and 3D magnetization-prepared rapid acquisition gradient echo (MPRAGE)) were adapted for high spatial resolution and good contrast of different tissues in the finger, while keeping acquisition time below 10 minutes...
March 10, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28292235/paramagnetic-and-superparamagnetic-inorganic-nanoparticles-for-t1-weighted-magnetic-resonance-imaging
#16
Leyong Zeng, Di Wu, Ruifen Zou, Tianxiang Chen, Jinchao Zhang, Aiguo Wu
Magnetic resonance imaging (MRI) has become a promising technique in the early diagnosis of cancers, especially the application of contrast agents can further enhance the detection limitation. Compared with the dark signal in "negative" contrast agents (T2), "positive" contrast agents (T1) with bright signal are more desirable for high-resolution imaging. However, the clinical used gadolinium complexes have short circulation time and the risk of nephrogenic system fibrosis. Therefore, to overcome the disadvantage of T2 agents and traditional T1 agents, it is very interesting to develop nano-scaled T1-weighted MRI contrast agents with safer and more precise imaging performance...
March 14, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28292199/high-resolution-mri-of-the-ulnar-and-radial-collateral-ligaments-of-the-wrist
#17
Taiki Nozaki, Wei Der Wu, Yasuhito Kaneko, Gregory Rafijah, Lily Yang, Dave Hitt, Hiroshi Yoshioka
Background Accurate diagnosis of injuries to the collateral ligaments of the wrist is technically challenging on MRI. Purpose To investigate usefulness of high-resolution two-dimensional (2D) and isotropic three-dimensional (3D) magnetic resonance imaging (MRI) for identifying and classifying the morphology of the ulnar and radial collateral ligaments (UCL and RCL) of the wrist. Material and Methods Thirty-seven participants were evaluated using 3T coronal 2D and isotropic 3D images by two radiologists independently...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28291265/t1-weighted-in-vivo-human-whole-brain-mri-dataset-with-an-ultrahigh-isotropic-resolution-of-250-%C3%AE-m
#18
Falk Lüsebrink, Alessandro Sciarra, Hendrik Mattern, Renat Yakupov, Oliver Speck
We present an ultrahigh resolution in vivo human brain magnetic resonance imaging (MRI) dataset. It consists of T1-weighted whole brain anatomical data acquired at 7 Tesla with a nominal isotropic resolution of 250 μm of a single young healthy Caucasian subject and was recorded using prospective motion correction. The raw data amounts to approximately 1.2 TB and was acquired in eight hours total scan time. The resolution of this dataset is far beyond any previously published in vivo structural whole brain dataset...
March 14, 2017: Scientific Data
https://www.readbyqxmd.com/read/28290070/parieto-frontal-gyrification-and-working-memory-in-healthy-adults
#19
Sophie Green, Karen Blackmon, Thomas Thesen, Jonathan DuBois, Xiuyuan Wang, Eric Halgren, Orrin Devinsky
Gyrification of the cortical mantle is a dynamic process that increases with cortical surface area and decreases with age. Increased gyrification is associated with higher scores on cognitive tasks in adults; however, the degree to which this relationship is independent of cortical surface area remains undefined. This study investigates whether regional variation in gyrification is associated with domain-general and domain-specific cognition. Our hypothesis is that increased local gyrification confers a functional advantage that is independent of surface area...
March 13, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28289798/-helpful-instrumental-examinations-in-idiopathic-parkinson-s-disease
#20
U Walter, H Zach, I Liepelt-Scarfone, W Maetzler
BACKGROUND: The clinical diagnosis of idiopathic Parkinson's disease (iPD) can be challenging. In these cases, additional diagnostic methods are available that can help to improve diagnostic accuracy. OBJECTIVES, MATERIAL AND METHODS: This article provides an overview of currently available and promising novel ancillary methods for the early and differential diagnosis of iPD. RESULTS: Imaging tools, such as 1.5 Tesla magnetic resonance imaging (MRI) and computed tomography (CT) are mainly used for the differentiation between iPD and symptomatic parkinsonian syndromes (PS)...
March 13, 2017: Der Nervenarzt
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