mr cartilage 5 tesla

INTRODUCTION: Magnetic resonance imaging (MRI) has been shown to be superior to radiography (XR) for assessing synovitis, osteitis, and bone erosion in rheumatoid arthritis (RA), particularly in clinical trials. However, relatively little has been reported on the ability of MRI to evaluate articular cartilage loss, or joint-space narrowing (JSN), in the hands and wrists. In a previous study, we adapted the nine-point Genant-modified Sharp XR-JSN score for use with MRI (MRI-JSN). In this study, we compare MRI-JSN with XR-JSN by using images from two multicenter clinical trials...

OBJECTIVES: To evaluate cartilage repair and native tissue using a three-dimensional (3D), radial, ultra-short echo time (UTE) (23)Na MR sequence without and with an inversion recovery (IR) preparation pulse for fluid suppression at 7 Tesla (T). METHODS: This study had institutional review board approval. We recruited 11 consecutive patients (41.5 ± 11.8 years) from an orthopaedic surgery practice who had undergone a knee cartilage restoration procedure. The subjects were examined postoperatively (median = 26 weeks) with 7-T MRI using: proton-T2 (TR/TE = 3,000 ms/60 ms); sodium UTE (TR/TE = 100 ms/0...

OBJECTIVE: To develop and characterize the MR properties of a synthetic model for cartilage extra-cellular matrix using hydrogels and to determine the concentration dependence of spin-lattice (T1) and spin-spin (T2) relaxation times of hydrogels and their glycosaminoglycan and collagen components in the presence and absence of gadopentetate dimeglumine (Gd-DTPA) for use in dGEMRIC. MATERIALS AND METHODS: T1 and T2 measurements were made at 3 Tesla on a range of gelatin (i...

Magnetic resonance (MR) imaging provides an excellent spatial resolution to visualize cartilage and define its main properties. Both 1.5 and especially 3 Tesla equipments have become very efficient in showing the whole articular cartilage and classifying the degenerative damage by analyzing morphological, structural and physical properties. MR evaluation of articular cartilage is of great clinical importance due to the prevalence of degenerative lesions and the development of new drugs and surgery-based treatments...

PURPOSE: To compare three-dimensional fast spin echo Cube (3D-FSE-Cube) with conventional 2D-FSE in MR imaging of the wrist. MATERIALS AND METHODS: The wrists of 10 volunteers were imaged in a 1.5 Tesla MRI scanner using an eight-channel wrist coil. The 3D-FSE-Cube images were acquired in the coronal plane with 0.5-mm isotropic resolution. The 2D-FSE images were acquired in both coronal and axial planes for comparison. An ROI was placed in fluid, cartilage, and muscle for SNR analysis...

The aim of the study was to describe the anatomy of the bovine tarsus using magnetic resonance imaging in a low-field scanner. T1-weighted transverse and sagittal images of five isolated hindlimbs were evaluated using a 0.5 Tesla magnet and a knee coil. The MR images were compared to corresponding frozen sections of cadaver limbs. Anatomical structures were labelled at each level. The resulting images provided excellent detail of the bovine tarsus. This study should serve as a basic reference for orthopaedic problems related to the tarsus in cattle...

PURPOSE: to create a custom-shaped graft through 3D tissue shape reconstruction and rapid-prototype molding methods using MRI data, and to test the accuracy of the custom-shaped graft against the original anatomical defect. METHODS: An iatrogenic defect on the distal femur was identified with a 1.5 Tesla MRI and its shape was reconstructed into a three-dimensional (3D) computer model by processing the 3D MRI data. First, the accuracy of the MRI-derived 3D model was tested against a laser-scan based 3D model of the defect...

OBJECTIVE: To evaluate the capability and limitation of magnetic resonance image(MRI)for Lumbar zygapophyseal joint cartilage through comparing pig lumbar zygapophyseal joint cartilage acquired from multiple MRI sequences of a 1.5 Tesla MR and gross specimens. METHODS: Six fresh lumbar spines from adult pigs were sagittaly scanned by Siemens 1.5 Tesla MR. The scan sequences included fast spin echo T1-weighted imaging (FSE T1WI), fast spin echo T2-weighted imaging (FSE T2 weighted T2WI), fat saturation proton density-weighted imaging (FS PDWI), 3-dimensional fast low angle shot imaging (3D-FLASH), and water excitation 3-dimensional fast low angle shot imaging (WE 3D-FLASH)...

The study's purpose was to assess the effect of multiplanar reconstruction on precision of weight-bearing medial and lateral femoral cartilage (cMF, cLF) morphometry in maloriented coronal MR images. Twenty knees were scanned four times with a 1.0 Tesla extremity imager using a fat-suppressed T1-weighted three-dimensional spoiled gradient recalled echo sequence; twice with "best as" double bull's-eye orientation of the femoral condyles, and once each with 5° internal and external rotation. Multiplanar reconstruction was applied to maloriented scans to recover double bull's-eye orientation...

OBJECTIVE: The aim of the study was to investigate the association of T2 relaxation times of the knee with early degenerative cartilage changes. Furthermore the impact of unloading the knee on T2 values was evaluated. METHODS: Forty-three patients with knee pain and an ICRS (International Cartilage Repair Society) cartilage defect grade <or=2 were examined with 3T magnetic resonance imaging (MRI). Morphological cartilage grading was based on high-resolution proton-density (PD), turbo-spin-echo (TSE) and three-dimensional (3D) isotropic True fast imaging with steady-state precession (FISP) images of slices covering the cartilage layer above the posterior horn of the meniscus...

BACKGROUND: In patients with osteoarthritis, a detailed assessment of degenerative cartilage disease is important to recommend adequate treatment. Using a representative sample of patients, this study investigated whether MRI is reliable for a detailed cartilage assessment in patients with osteoarthritis of the knee. METHODS: In a cross sectional-study as a part of a retrospective case-control study, 36 patients (mean age 53.1 years) with clinically relevant osteoarthritis received standardized MRI (sag...

PURPOSE: To determine the feasibility of performing MRI of the wrist at 7 Tesla (T) with parallel imaging and to evaluate how acceleration factors (AF) affect signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and image quality. MATERIALS AND METHODS: This study had institutional review board approval. A four-transmit eight-receive channel array coil was constructed in-house. Nine healthy subjects were scanned on a 7T whole-body MR scanner. Coronal and axial images of cartilage and trabecular bone micro-architecture (3D-Fast Low Angle Shot (FLASH) with and without fat suppression, repetition time/echo time = 20 ms/4...

Whereas the strength of scoring systems in osteoarthritis (OA) lies in detecting local changes, involving small parts of the structures of interest (ie, cartilage lesions), quantitative measures are powerful where minute changes occur homogeneously throughout large structures. Cartilage measurements at 1.5 or 3 Tesla are technically accurate, reproducible, and sensitive to change. The rate of change in knee OA was found to be 1% to 2% annually. Risk factors of cartilage loss include a high BMI, meniscal pathology, malalignment, advanced radiographic OA, bone marrow alterations, and focal cartilage lesions...

OBJECTIVE: The purpose of this study was to evaluate the feasibility, quality, and possible future implications of magnetic resonance imaging (MRI) of the human hand and wrist at 7 T. MATERIALS AND METHODS: Images of the left hand of a healthy volunteer were acquired with a 7- and a 1.5-T whole body system and comparatively analyzed. Axial and coronal two-dimensional gradient echo (GRE) images with inflow saturation, coronal 3D GRE images, and time-of-flight angiographies were obtained without averaging...

Magnetic resonance imaging (MRI) at 7.0 T has the potential for higher signal-to-noise ratio (SNR), improved spectral resolution, and faster imaging compared with 1.5-T and 3.0-T MR systems. This is especially interesting for challenging imaging regions like the wrist and the hand because of the small size of the visualized anatomical structures; the increase in SNR could then be directly converted into higher spatial resolution of the images. Practically, imaging at 7.0 T poses a variety of technical challenges such as static (B (0)) and radiofrequency (B (1)) homogeneities, shimming, chemical shift artifacts, susceptibility artifacts, alterations in tissue contrast, specific absorption rate limitations, coil construction, and pulse sequence tuning...

Magnetic resonance imaging (MRI) at 3.0 T has become increasingly available for clinical usage. Its clinical impact on diagnostic outcome compared with 1.5 T still remains unclear, however, because no larger case series have been published until now. In addition, the further development of clinical applications is still limited at 3.0 T due to the lack of availability of dedicated coils and the sensitivity of 3.0 T to artifacts. However, especially in the MR imaging of small joints, there seems to be a great potential in improving the diagnostic performance of MRI with increased signal-to-noise ratio by increasing the spatial resolution...

Normal and degenerated cartilages have different magnetic resonance (MR) capillary permeability (K(trans)) and interstitial interchangeable volume (v(e)). Our hypothesis was that glucosamine sulfate treatment modifies these neovascularity abnormalities in osteoarthritis. Sixteen patients with patella degeneration, randomly distributed into glucosamine or control groups, underwent two 1.5-Tesla dynamic contrast-enhanced MR imaging studies (treatment initiation and after 6 months). The pain visual analog scale (VAS) and American Knee Society (AKS) score were used...

OBJECTIVE: The aims of this study were to evaluate the spatial distribution of cartilage structure in controls and patients, and to quantitatively assess the cartilage overlying bone marrow edema-like lesion (BMEL) and within defined cartilage compartments in knees with anterior cruciate ligament (ACL) tears using T1rho mapping technique at 3 T magnetic resonance imaging. MATERIALS AND METHODS: The knee joints of 15 healthy controls (4 women, 11 men, mean age = 30...

STUDY DESIGN: Prospective in vivo study of meniscoids in the cervical zygapophyseal joints. OBJECTIVE: To generate reference data for in vivo magnetic resonance (MR) imaging properties of meniscoids in the cervical zygapophyseal joints. SUMMARY OF BACKGROUND DATA: Meniscoids, also called synovial folds, are tiny anatomic structures within the zygapophyseal joints. It has been suggested that pathologic conditions of meniscoids may be a potential source of cervical pain...

INTRODUCTION: Ultra-high-field whole-body systems (7.0 T) have a high potential for future human in vivo magnetic resonance imaging (MRI). In musculoskeletal MRI, biochemical imaging of articular cartilage may benefit, in particular. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T2 mapping have shown potential at 3.0 T. Although dGEMRIC, allows the determination of the glycosaminoglycan content of articular cartilage, T2 mapping is a promising tool for the evaluation of water and collagen content...