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Athens protocol procedure

G Kakourou, S Kahraman, G C Ekmekci, H A Tac, G Kourlaba, E Kourkouni, A Cervero Sanz, J Martin, H Malmgren, C Giménez, V Gold, F Carvalho, C Billi, J F C Chow, X Vendrell, G Kokkali, J Liss, J Steffann, J Traeger-Synodinos
STUDY QUESTION: Has PGD-HLA been successful relative to diagnostic and clinical efficacy? SUMMARY ANSWER: The diagnostic efficacy of PGD-HLA protocols was found lower in this study in comparison to published PGD-HLA protocols and to that reported for general PGD by ESHRE (78.5 vs 94.1% and vs 92.6%, respectively), while the clinical efficacy has proven very difficult to assess due to inadequate follow-up of both the ART/PGD and HSCT procedure outcomes. WHAT IS KNOWN ALREADY: The first clinical cases for PGD-HLA were reported in 2001...
February 8, 2018: Human Reproduction
Grace J Young, Amanda L Lewis, J Athene Lane, Helen L Winton, Marcus J Drake, Peter S Blair
BACKGROUND: Current management for men with lower urinary tract symptoms (LUTS) is a pathway that results in prostate surgery in a significant proportion. While helpful in relieving benign prostatic obstruction (BPO), surgery may be ineffective for men suffering from difficulties not relating to BPO. The UPSTREAM trial started recruitment in October 2014 with the aim of establishing whether a care pathway including urodynamics (a diagnostic tool for BPO and thus an indication of whether surgery is needed) is no worse for men, in terms of symptomatic outcome, than one without (routine care)...
October 3, 2017: Trials
Antoniadou Maria, Paximada Charikleia, Lagouvardos Panagiotis
OBJECTIVES: Repair versus replacement of a defective direct restoration is one important step for conserving tooth structure. This study was designed to collect information on the attitudes of Greek dentists towards repairing direct restorations. METHODS: An electronic questionnaire with 16 multiple-choice and rank-ordering questions was created online and its URL address was randomly emailed to 800 dentists in the area of Athens, Greece. The questionnaire remained open for 3 months, and after two reminder emails the data collected were analysed statistically to identify differences between clinician's sex or years of practicing dentistry, using the chi-square and Kruskal-Wallis tests at α = 0...
July 23, 2017: International Dental Journal
Irene Karampela, Evangelos Tzortzis, Ioanna Kefala, Eleutheria Zygoura, Vasiliki Mantzana, Apostolos Armaganidis
Quality standards (QS) support and enhance health care services provided to patients and citizens, especially in sophisticated medical departments, such as Intensive Care Units (ICU). However, ICU staff lag behind in the adoption and compliance of QS protocols. In this paper, QS protocols implemented in the Intensive Care Unit of the Attiko University Hospital, a tertiary teaching hospital of the University of Athens, will be discussed. In this hospital, standardized procedures are implemented through the HIS, facilitating routine administration and services...
2017: Studies in Health Technology and Informatics
Jo Worthington, Hilary Taylor, Paul Abrams, Sara T Brookes, Nikki Cotterill, Sian M Noble, Tobias Page, K Satchi Swami, J Athene Lane, Hashim Hashim
BACKGROUND: Transurethral resection of the prostate (TURP) has been the standard operation for benign prostatic obstruction (BPO) for 40 years, with approximately 25,000 procedures performed annually, and has remained largely unchanged. It is generally a successful operation, but has well-documented risks for the patient. Thulium laser transurethral vaporesection of the prostate (ThuVARP) vaporises and resects the prostate using a surgical technique similar to TURP. The small amount of study data currently available suggests that ThuVARP may have certain advantages over TURP, including reduced blood loss and shorter hospital stay, earlier return to normal activities, and shorter duration of catheterisation...
April 17, 2017: Trials
Anastasios John Kanellopoulos, Emerson M Cruz, Robert Edward T Ang, George Asimellis
BACKGROUND: To compare intraocular pressure (IOP) changes following topical dexamethasone administration for 1 month in keratoconic versus normal eyes. METHODS: This is a retrospective, single-center, non-randomized case series evaluation of 350 eyes. Two groups were formed: normal/control Group A (nA =73), eyes that underwent excimer laser photorefractive keratectomy; and keratoconic (KCN) Group B (nB =277), eyes that were subjected to partial laser photorefractive keratectomy combined with collagen cross-linking (The Athens Protocol)...
2016: Eye and Vision (London, England)
Anastasios John Kanellopoulos, George Asimellis
PURPOSE: To comparatively investigate the efficacy of the enhanced Athens Protocol procedure guided by novel Placido-derived topography with cyclorotation compensation (the cyclorotation adjusted group) to similar cases guided by Scheimpflug-derived tomography without cyclorotation compensation (the non-cyclorotation adjusted group). METHODS: Two groups were evaluated: the cyclorotation adjusted group (n = 110 eyes) and the non-cyclorotation adjusted group (n = 110 eyes)...
November 2015: Journal of Refractive Surgery
Julia Wade, Derek J Rosario, Joanne Howson, Kerry N L Avery, C Elizabeth Salter, M Louise Goodwin, Jane M Blazeby, J Athene Lane, Chris Metcalfe, David E Neal, Freddie C Hamdy, Jenny L Donovan
BACKGROUND: The histological diagnosis of prostate cancer requires a prostate needle biopsy. Little is known about the relationship between information provided to prepare men for transrectal ultrasound guided biopsy (TRUS-Bx) and how men experience biopsy. The objectives were a) to understand men's experiences of biopsy as compared to their expectations; and b) to propose current evidence-based information for men undergoing TRUS-Bx. METHODS: Between February 2006 and May 2008, 1,147 men undergoing a standardised 10-core transrectal ultrasound guided biopsy protocol under antibiotic cover following a PSA 3...
February 28, 2015: BMC Health Services Research
Anastasios John Kanellopoulos, George Asimellis
PURPOSE: To investigate refractive, topometric, pachymetric, and visual rehabilitation changes induced by anterior surface normalization for keratoconus by partial topography-guided excimer laser ablation in conjunction with accelerated, high-fluence cross-linking. METHODS: Two hundred thirty-one keratoconic cases subjected to the Athens Protocol procedure were studied for visual acuity, keratometry, pachymetry, and anterior surface irregularity indices up to 3 years postoperatively by Scheimpflug imaging (Oculus Optikgeräte GmbH, Wetzlar, Germany)...
February 2014: Journal of Refractive Surgery
Alexandros G Asimakopoulos, Lei Wang, Nikolaos S Thomaidis, Kurunthachalam Kannan
A liquid-liquid extraction (LLE; ethyl acetate) protocol, followed by liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) methodology, was developed for the determination of 19 compounds, including bisphenol A diglycidyl ethers (BADGEs; industrial ethers), benzophenone-type UV filters (BP-UV filters; precursors and metabolites), p-hydroxybenzoic acid esters (parabens; preservatives), triclosan (TCS) and triclocarban (TCC) in human urine. Urine specimens were enzymatically deconjugated with β-glucuronidase (from Helix pomatia) and extracted by a LLE procedure for the measurement of total concentrations (i...
January 10, 2014: Journal of Chromatography. A
Diogo Costa, Joaquim J F Soares, Jutta Lindert, Eleni Hatzidimitriadou, Andreas Karlsso, Örjan Sundin, Olga Toth, Ellisabeth Ioannidi-Kapolou, Olivier Degomme, Jorge Cervilla, Henrique Barros
OBJECTIVE: To describe the design, methods, procedures and characteristics of the population involved in a study designed to compare Intimate Partner Violence (IPV) in eight European countries. METHODS: Women and men aged 18-65, living in Ghent-Belgium (n = 245), Stuttgart-Germany (n = 546), Athens-Greece (n = 548), Budapest-Hungary (n = 604), Porto-Portugal (n = 635), Granada-Spain (n = 138), Östersund-Sweden (n = 592), London-United Kingdom (n = 571), were sampled and administered a common questionnaire...
November 2013: Gaceta Sanitaria
Rhiannon C Macefield, Andrew D Beswick, Jane M Blazeby, J Athene Lane
BACKGROUND: Monitoring the conduct of clinical trials is recommended by International Conference of Harmonisation Good Clinical Practice (ICH GCP) guidelines and is integral to trial quality assurance. On-site monitoring, that is, visiting trial sites, is one part of this process but little is known about the procedures that are performed in practice. PURPOSE: To examine and summarise published on-site monitoring methods for health-care clinical trials, including evaluations of their benefits and costs to trials...
February 2013: Clinical Trials: Journal of the Society for Clinical Trials
Stamatia Daroglou, Donald J Viglione
Ninety-eight adult nonpatients from Greece were administered the Rorschach according to the Rorschach Comprehensive Systems (CS; Exner, 2003) procedures. These participants were of Greek heritage, were older than 21 years of age, and resided in Greece. Participants were residents of an urban area, Athens, as well as residents of provincial areas including smaller cities and villages. The examiner was a native Greek and of Greek heritage and administered the protocols in Greek. Exclusion criteria are described...
2007: Journal of Personality Assessment
Phaedra Dora Simitsek, Panagiota Giannikopoulou, Haralabos Katsoulas, Efstathios Sianos, George Tsoupras, Maria-Helen Spyridaki, Costas Georgakopoulos
Hemoglobin-based oxygen carriers (HBOCs) are blood substitutes based on hemoglobin of either bovine or human origin and they can potentially be misused in elite sports to improve endurance performance. Recently, three methods have been proposed in doping control analysis to allow HBOCs screening and identification by application of electrophoresis, size-exclusion chromatography coupled with HPLC and LC coupled with tandem mass spectrometry (LC/MSMS). In view of the Athens 2004 Olympic Games, modifications were introduced in order to increase the specificity of these methods...
February 5, 2007: Analytica Chimica Acta
E Riza, P Kyriakogianni-Psaropoulou, E Koumantakis, H Symiakaki, I Garas, A Linos
The aim of this study was to describe the state of the art in cervical cancer screening in Greece by presenting the two regionally organised screening programmes that currently operate in the country. Both programmes were initiated in 1991 and are partly funded by the European Union. The Ormylia screening programme covers the population of Halkidiki (Northern Greece), a predominantly rural area. The second programme covers the regions of Messinia and Ilia (Southern Greece). Both programmes are targeted at women aged 25-64 years of age and a Papanicolaou (Pap) smear test is recommended every 2-3 years...
November 2000: European Journal of Cancer
N J Lygidakis, M Thodorakopoulou, G Dedemadi, N Spenzouris, A Kyriakou, K Gemos, S Kekic, J Protopsaltis, A Pearl
BACKGROUND/AIM: Despite remarkable advances in diagnostic and therapeutic techniques for metastatic liver disease, this disease remains a challenge for patients and surgeons. In this study we describe our experience in the management of 21 patients referred for treatment due to metastatic disease, between 1992 and 1997, in Athens, Greece. METHODOLOGY: Patients diagnosed with unresectable liver tumors, received a standard treatment, which included neo-adjuvant locoregional immuno-chemotherapy, surgical resection and adjuvant locoregional immuno-chemotherapy...
November 1997: Hepato-gastroenterology
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