Jean-François Delattre, Romain Cohen, Jean-François Emile, Frédéric Bibeau, Chloé Broudin, Julien Taieb, Thierry André, Magali Svrcek
The management of colorectal cancer (CRC) relies heavily on TNM staging. In order to improve this staging, it is essential to identify all histological markers bearing a significant prognostic value. Among these, tumor deposits (TDs), defined as tumor foci in the pericolonic or perirectal adipose tissue with no residual lymph node tissue, have been shown to be associated with poor prognosis in cohort studies leading to their individualization in the TNM7 classification as pN1c. However, TDs are only considered in the absence of lymph node metastases...
November 2021: Annales de Pathologie