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Multi channel monitor

Ashutosh Fular, Anil Kumar Sharma, Sachin Kumar, Gaurav Nagar, Gajanan Chigure, D D Ray, Srikant Ghosh
Tick-borne diseases is a global threat and tick resistance to commonly used acaricides is a growing problem, thus calling for improved resistance monitoring tools. To aid in monitoring of resistance in field tick populations, a resistant colony of Rhipicephalus microplus was characterized with the aim to establish a reference multi-acaricide resistant tick strain. Using a standardized adult immersion test, the Lethal Concentration(LC)50 values for deltamethrin, cypermethrin, fenvalerate and diazinon against the laboratory selected resistant tick (LSRT) strain were determined as 306...
April 22, 2018: Ticks and Tick-borne Diseases
Chiedza F Munyeza, Onkarabile Dikale, Egmont R Rohwer, Patricia B C Forbes
A plunger assisted solvent extraction (PASE) method for multi-channel silicone rubber trap samplers was developed and evaluated as an alternative to direct thermal desorption for the monitoring of polycyclic aromatic hydrocarbons (PAHs). The proposed extraction method was simple, fast (a total of 2 min for extraction), and used a small volume of solvent (a total of 2 mL from two sequential 1 mL extractions). The PASE method presented an advantage over thermal desorption in that samples could be re-analyzed, as only a portion of the extract was injected...
April 23, 2018: Journal of Chromatography. A
V Shumakova, S Ališauskas, P Malevich, C Gollner, A Baltuška, D Kartashov, A M Zheltikov, A V Mitrofanov, A A Voronin, D A Sidorov-Biryukov, A Pugžlys
Properties of filaments ignited by multi-millijoule, 90 fs mid-infrared pulses centered at 3.9 μm are examined experimentally by monitoring plasma density, losses, spectral dynamics and beam profile evolution at different focusing strengths. By changing from strong (f=0.25  m) to loose (f=7  m) focusing, we observe a shift from plasma-assisted filamentation to filaments with low plasma density. In the latter case, filamentation manifests itself by beam self-symmetrization and spatial self-channeling...
May 1, 2018: Optics Letters
Robert Brockway, Marina Brockway, Brian Brockway, Robert Hamlin
INTRODUCTION: FDA has established initiatives to characterize clinical and non-clinical biomarkers to enable more precise prediction of proarrhythmia risk based upon knowledge of drug effect on multiple cardiac ion channels (Colatsky et al., 2016). The FDA has recently demonstrated superiority of early ventricular repolarization interval (JTp) in differentiating pure hERG block from multi-channel block in human subjects. Preclinical studies often acquire a single lead ECG, whereas FDA measurements of JTp were derived ​from a spatial vectorcardiogram computed using multiple leads...
April 25, 2018: Journal of Pharmacological and Toxicological Methods
Wei Huang, Limei Yang, Gang Yang, Feng Li
A microfluidic laser scattering system for rapid and label-free detection of single waterborne parasites in microfluidic flows was designed, fabricated and demonstrated. The key novelty of the system lies in the integration of functional modules involving pre-concentration, on-chip laser scattering detection, and pattern recognition. The silicon-based pre-concentration chip can concentrate 10 ml reagent water sample spiked with protozoa (oo)cysts into a volume of 200 μl in ~30 minutes. The concentrated sample is further channeled into the on-chip laser scattering detection module at a flow rate of 10 μl/min, which can collect the multi-angle scattering pattern of single flowing microparticles...
April 1, 2018: Biomedical Optics Express
Fengbo Zhu, Ji Lin, Zi Liang Wu, Shaoxing Qu, Jun Yin, Jin Qian, Qiang Zheng
Conductive polymer hydrogels (CPHs) that combine the unique properties of hydrogels and electronic properties of conductors have shown their great potentials in wearable/implantable electronic devices, where materials with remarkable mechanical properties, high conductivity and easy processability are demanding. Here we have developed a new type of polyion complex/polyaniline (PIC/PAni) hybrid hydrogels that are tough, conductive and can be facilely patterned. The incorporation of conductive phase (PAni) into PIC matrix through phytic acid resulted in hybrid gels with ~65 wt% water, high conductivity while maintaining the key viscoelasticity of the tough matrix...
April 2, 2018: ACS Applied Materials & Interfaces
Barry M Davis, Benoit Gervais, John G McCaffrey
A detailed characterisation of the luminescence recorded for the 6p1 P1 -6s1 S0 transition of atomic barium isolated in annealed solid xenon has been undertaken using two-dimensional excitation-emission (2D-EE) spectroscopy. In the excitation spectra extracted from the 2D-EE scans, two dominant thermally stable sites were identified, consisting of a classic, three-fold split Jahn-Teller band, labeled the blue site, and an unusual asymmetric 2 + 1 split band, the violet site. A much weaker band has also been identified, whose emission is strongly overlapped by the violet site...
March 28, 2018: Journal of Chemical Physics
Armen A Gharibans, Benjamin L Smarr, David C Kunkel, Lance J Kriegsfeld, Hayat M Mousa, Todd P Coleman
The increasing prevalence of functional and motility gastrointestinal (GI) disorders is at odds with bottlenecks in their diagnosis, treatment, and follow-up. Lack of noninvasive approaches means that only specialized centers can perform objective assessment procedures. Abnormal GI muscular activity, which is coordinated by electrical slow-waves, may play a key role in symptoms. As such, the electrogastrogram (EGG), a noninvasive means to continuously monitor gastric electrical activity, can be used to inform diagnoses over broader populations...
March 22, 2018: Scientific Reports
Muge Yucel, Osman Akin, Mehmet Cayoren, Ibrahim Akduman, Alagappan Palaniappan, Bo Liedberg, Gurkan Hizal, Fatih Inci, Umit Hakan Yildiz
This study reports on a hand-held volatilome analyzer for selective determination of clinically relevant biomarkers in exhaled breath. The sensing platform is based on electrospun polymer nanofiber-multiwalled carbon nanotube (MWCNT) sensing microchannels. Polymer nanofibers of poly(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(methyl methacrylate) (PMMA) incorporated with MWCNT exhibits a stable response to interferences of humidity and CO2 and provides selective deformations upon exposure of exhaled breath target volatilomes acetone and toluene, exhibiting correlation to diabetes and lung cancer, respectively...
April 17, 2018: Analytical Chemistry
Hui Lu, Li Zhu, Chuanlong Zhang, Kexiang Chen, Yiping Cui
To solve the problem that analyte molecules cannot easily enter "hot spots" on a conventional solid SERS substrate, we developed a mixing-assisted "hot spots" occupying (MAHSO) SERS strategy to improve utilization of "hot spots". Compared with the conventional substrate, the MAHSO substrate enhances the sensitivity of SERS measurement by thousands of times. The MAHSO substrate possesses excellent properties of high enhancement, high uniformity, and long-term stability because the MAHSO substrate is integrated inside an ultrafast microfluidic mixer...
April 3, 2018: Analytical Chemistry
J Pandia Rajan, S Edward Rajan
BACKGROUND: Wireless physiological signal monitoring system designing with secured data communication in the health care system is an important and dynamic process. OBJECTIVE: We propose a signal monitoring system using NI myRIO connected with the wireless body sensor network through multi-channel signal acquisition method. Based on the server side validation of the signal, the data connected to the local server is updated in the cloud. The Internet of Things (IoT) architecture is used to get the mobility and fast access of patient data to healthcare service providers...
2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
Ana C Fernandes, Daria Semenova, Peter Panjan, Adama M Sesay, Krist V Gernaey, Ulrich Krühne
The limited availability of metabolite-specific sensors for continuous sampling and monitoring is one of the main bottlenecks contributing to failures in bioprocess development. Furthermore, only a limited number of approaches exist to connect currently available measurement systems with high throughput reactor units. This is especially relevant in the biocatalyst screening and characterization stage of process development. In this work, a strategy for sensor integration in microfluidic platforms is demonstrated, to address the need for rapid, cost-effective and high-throughput screening in bioprocesses...
March 6, 2018: New Biotechnology
Sabino J Pietrangelo, Hae-Seung Lee, Charles G Sodini
OBJECTIVE:  Practical deficiencies related to conventional transcranial Doppler (TCD) sonography have restricted its use and applicability. This work seeks to mitigate several such constraints through the development of a wearable, electronically steered TCD velocimetry system, which enables noninvasive measurement of cerebral blood flow velocity (CBFV) for monitoring applications with limited operator interaction. MATERIALS AND METHODS: A highly-compact, discrete prototype system was designed and experimentally validated through flow phantom and preliminary human subject testing...
2018: Acta Neurochirurgica. Supplement
Richárd Fiáth, Katharina T Hofer, Vivien Csikós, Domonkos Horváth, Tibor Nánási, Kinga Tóth, Frederick Pothof, Christian Böhler, Maria Asplund, Patrick Ruther, István Ulbert
Stereo-electroencephalography depth electrodes, regularly implanted into drug-resistant patients with focal epilepsy to localize the epileptic focus, have a low channel count (6-12 macro- or microelectrodes), limited spatial resolution (0.5-1 cm) and large contact area of the recording sites (~mm2). Thus, they are not suited for high-density local field potential and multiunit recordings. In this paper, we evaluated the long-term electrophysiological recording performance and histocompatibility of a neural interface consisting of 32 microelectrodes providing a physical shape similar to clinical devices...
February 26, 2018: Biomedizinische Technik. Biomedical Engineering
Stavros I Dimitriadis, Christos Salis, David Linden
OBJECTIVE: Limitations of the manual scoring of polysomnograms, which include data from electroencephalogram (EEG), electro-oculogram (EOG), electrocardiogram (ECG) and electromyogram (EMG) channels have long been recognized. Manual staging is resource intensive and time consuming, and thus considerable effort must be spent to ensure inter-rater reliability. As a result, there is a great interest in techniques based on signal processing and machine learning for a completely Automatic Sleep Stage Classification (ASSC)...
April 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Lena Hellström-Westas
The amplitude-integrated electroencephalogram (aEEG) is a filtered and compressed EEG trend that can be used for long-term monitoring of brain function in patients of all ages. aEEG is increasingly used in neonatal intensive care units since several studies have shown its utility in high-risk newborn infants. Main indications for aEEG monitoring include early evaluation of brain function after perinatal asphyxia and seizure detection. The aEEG is usually recorded from one or two channels derived from parietal, central, or frontal leads...
February 13, 2018: Seminars in Fetal & Neonatal Medicine
Ram M Narayanan, Richard K Pooler, Anthony F Martone, Kyle A Gallagher, Kelly D Sherbondy
This paper describes a multichannel super-heterodyne signal analyzer, called the Spectrum Analysis Solution (SAS), which performs multi-purpose spectrum sensing to support spectrally adaptive and cognitive radar applications. The SAS operates from ultrahigh frequency (UHF) to the S-band and features a wideband channel with eight narrowband channels. The wideband channel acts as a monitoring channel that can be used to tune the instantaneous band of the narrowband channels to areas of interest in the spectrum...
February 22, 2018: Sensors
Nathan J Stevenson, Sampsa Vanhatalo
Neonatal seizures are widely considered a neurological emergency with a need for prompt treatment, yet they are known to present a highly elusive target for bedside clinicians. Recent studies have suggested that the design of a neonatal seizure treatment trial will profoundly influence the sample size, which may readily increase to hundreds or even thousands as the achieved effect size diminishes to clinical irrelevance. The self-limiting and rapidly resolving nature of neonatal seizures diminishes the measurable treatment effect every hour after seizure onset and any effect may potentially be confused with spontaneous resolution, precluding the value of many observational studies...
February 12, 2018: Seminars in Fetal & Neonatal Medicine
Richárd Fiáth, Bogdan Cristian Raducanu, Silke Musa, Alexandru Andrei, Carolina Mora Lopez, Chris van Hoof, Patrick Ruther, Arno Aarts, Domonkos Horváth, István Ulbert
In this study, we developed and validated a single-shank silicon-based neural probe with 128 closely-packed microelectrodes suitable for high-resolution extracellular recordings. The 8-mm-long, 100-µm-wide and 50-µm-thick implantable shank of the probe fabricated using a 0.13-µm complementary metal-oxide-semiconductor (CMOS) metallization technology contains square-shaped (20 × 20 µm2 ), low-impedance (~ 50 kΩ at 1 kHz) recording sites made of rough and porous titanium nitride which are arranged in a 32 × 4 dense array with an inter-electrode pitch of 22...
May 30, 2018: Biosensors & Bioelectronics
Shuai Wang, Bingxin Xu, Xinyu Fan, Zuyuan He
Wavelength-division multiplexing (WDM) schemes have greatly increased optical transmission capacity, especially when using massively parallel optical frequency combs (OFCs) as carriers. In this paper, we show that linear optical sampling (LOS) is a kind of multiheterodyne process and it can be performed with arbitrary-shaped periodic waveforms. Meanwhile, it can be used for characterizing WDM signals with only a single receiving channel. We successfully demonstrate an observation of 40 WDM channels with 1 THz total bandwidth and total 800 Gbit/s data rate by only using one sampling channel...
January 22, 2018: Optics Express
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