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https://www.readbyqxmd.com/read/29092192/simultaneous-four-channel-thermal-adaptation-of-polarization-insensitive-silicon-photonics-wdm-receiver
#1
Robert Gatdula, Kwangwoong Kim, Argishti Melikyan, Young-Kai Chen, Po Dong
We propose a novel approach to demonstrate simultaneous multi-wavelength locking during temperature changes in a silicon photonic polarization insensitive microring-based wavelength division multiplexing (WDM) receiver. The DC component of a single monitoring photodetector at the through port of the microring filter array is exploited as a feedback signal with no additional power consumption. This feedback signal is used in control circuitry to properly tune the microring filters using ohmic heating, thus creating a feedback loop for thermal adaptation...
October 30, 2017: Optics Express
https://www.readbyqxmd.com/read/29089896/a-comparative-study-on-fetal-heart-rates-estimated-from-fetal-phonography-and-cardiotocography
#2
Emad A Ibrahim, Shamsa Al Awar, Zuhur H Balayah, Leontios J Hadjileontiadis, Ahsan H Khandoker
The aim of this study is to investigate that fetal heart rates (fHR) extracted from fetal phonocardiography (fPCG) could convey similar information of fHR from cardiotocography (CTG). Four-channel fPCG sensors made of low cost (<$1) ceramic piezo vibration sensor within 3D-printed casings were used to collect abdominal phonogram signals from 20 pregnant mothers (>34 weeks of gestation). A novel multi-lag covariance matrix-based eigenvalue decomposition technique was used to separate maternal breathing, fetal heart sounds (fHS) and maternal heart sounds (mHS) from abdominal phonogram signals...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29080563/advanced-control-synthesis-for-reverse-osmosis-water-desalination-processes
#3
Bui Duc Hong Phuc, Sam-Sang You, Hyeung-Six Choi, Seok-Kwon Jeong
  In this study, robust control synthesis has been applied to a reverse osmosis desalination plant whose product water flow and salinity are chosen as two controlled variables. The reverse osmosis process has been selected to study since it typically uses less energy than thermal distillation. The aim of the robust design is to overcome the limitation of classical controllers in dealing with large parametric uncertainties, external disturbances, sensor noises, and unmodeled process dynamics. The analyzed desalination process is modeled as a multi-input multi-output (MIMO) system with varying parameters...
November 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/29060515/physical-activity-classification-using-time-frequency-signatures-of-motion-artifacts-in-multi-channel-electrical-impedance-plethysmographs
#4
Hassan Aqeel Khan, Amit Gore, Jeff Ashe, Shantanu Chakrabartty
Physical activities are known to introduce motion artifacts in electrical impedance plethysmographic (EIP) sensors. Existing literature considers motion artifacts as a nuisance and generally discards the artifact containing portion of the sensor output. This paper examines the notion of exploiting motion artifacts for detecting the underlying physical activities which give rise to the artifacts in question. In particular, we investigate whether the artifact pattern associated with a physical activity is unique; and does it vary from one human-subject to another? Data was recorded from 19 adult human-subjects while conducting 5 distinct, artifact inducing, activities...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057872/modelling-torsade-de-pointes-arrhythmias-in-vitro-in-3d-human-ips-cell-engineered-heart-tissue
#5
Masahide Kawatou, Hidetoshi Masumoto, Hiroyuki Fukushima, Gaku Morinaga, Ryuzo Sakata, Takashi Ashihara, Jun K Yamashita
Torsade de Pointes (TdP) is a lethal arrhythmia that is often drug-induced, thus there is an urgent need for development of models to test or predict the drug sensitivity of human cardiac tissue. Here, we present an in vitro TdP model using 3D cardiac tissue sheets (CTSs) that contain a mixture of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and non-myocytes. We simultaneously monitor the extracellular field potential (EFP) and the contractile movement of the CTSs. Upon treatment with IKr channel blockers, CTSs exhibit tachyarrhythmias with characteristics of TdP, including both a typical polymorphic EFP and meandering spiral wave re-entry...
October 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/29041476/segmented-detection-spr-sensor-based-on-seven-core-fiber
#6
Yong Wei, Yudong Su, Chunlan Liu, Yonghui Zhang, Xiangfei Nie, Zhihai Liu, Yu Zhang, Feng Peng
By using a seven-core fiber (SCF), we propose and demonstrate a novel segmented detection SPR sensor, which solves two bottlenecks about the fiber SPR sensor of low sensitivity and the difficulty in the multichannel detection. The proposed sensor has ultra high sensitivity and wide detection range because of employing the segmented detection technology. Besides that, the proposed sensor employs reflection-type time division multiplexing (TDM) technology in fiber multichannel detection for the first time. We couple light into and out of the six circularly symmetric distributed cores of the seven-core fiber to realize the three channel SPR sensing and testing...
September 4, 2017: Optics Express
https://www.readbyqxmd.com/read/29020445/direct-metal-writing-and-precise-positioning-of-gold-nanoparticles-within-microfluidic-channels-for-sers-sensing-of-gaseous-analytes
#7
Mian Rong Lee, Hiang Kwee Lee, Yijie Yang, Charlynn Sher Lin Koh, Chee Leng Lay, Yih Hong Lee, In Yee Phang, Xing Yi Ling
We demonstrate a one-step precise direct metal writing of well-defined and densely packed gold nanoparticle (AuNP) patterns with tunable physical and optical properties. We achieve this by using two-photon lithography on a Au precursor comprising poly(vinylpyrrolidone) (PVP) and ethylene glycol (EG), where EG promotes higher reduction rates of Au(III) salt via polyol reduction. Hence, clusters of monodisperse AuNP are generated along raster scanning of the laser, forming high-particle-density, well-defined structures...
November 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29018638/automatic-sleep-monitoring-using-ear-eeg
#8
Takashi Nakamura, Valentin Goverdovsky, Mary J Morrell, Danilo P Mandic
The monitoring of sleep patterns without patient's inconvenience or involvement of a medical specialist is a clinical question of significant importance. To this end, we propose an automatic sleep stage monitoring system based on an affordable, unobtrusive, discreet, and long-term wearable in-ear sensor for recording the electroencephalogram (ear-EEG). The selected features for sleep pattern classification from a single ear-EEG channel include the spectral edge frequency and multi-scale fuzzy entropy, a structural complexity feature...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28966475/centrifugal-microfluidics-for-sorting-immune-cells-from-whole-blood
#9
Zeta Tak For Yu, Jophin George Joseph, Shirley Xiaosu Liu, Mei Ki Cheung, Parker James Haffey, Katsuo Kurabayashi, Jianping Fu
Sorting and enumeration of immune cells from blood are critical operations involved in many clinical applications. Conventional methods for sorting and counting immune cells from blood, such as flow cytometry and hemocytometers, are tedious, inaccurate, and difficult for implementation for point-of-care (POC) testing. Herein we developed a microscale centrifugal technology termed Centrifugal Microfluidic Chip (CMC) capable of sorting immune cells from blood and in situ cellular analysis in a laboratory setting...
June 2017: Sensors and Actuators. B, Chemical
https://www.readbyqxmd.com/read/28943300/effect-of-chaotropes-on-the-kinetics-of-iron-release-from-ferritin-by-flavin-nucleotides
#10
Lindsay E Johnson, Tyler Wilkinson, Paolo Arosio, Artem Melman, Fadi Bou-Abdallah
BACKGROUND: Ferritins are ubiquitous multi-subunit iron storage and detoxification proteins that play a critical role in iron homeostasis. Ferrous ions that enter the protein's shell through hydrophilic channels are rapidly oxidized at dinuclear centers on the H-subunit before transfer to the protein's cavity for storage. The mechanisms of iron loading have been extensively studied, but little is known about iron mobilization. Fe(III) reduction can occur via rapid reduction by suitable reducing agents followed by chelation of Fe(II) ions or via direct and slow Fe(III) chelation...
December 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28905426/optically-controlled-on-coil-amplifier-with-rf-monitoring-feedback
#11
Natalia Gudino, Jacco A de Zwart, Qi Duan, Stephen J Dodd, Joe Murphy-Boesch, Peter van Gelderen, Jeff H Duyn
PURPOSE: To develop a new optically controlled on-coil amplifier that facilitates safe use of multi-channel radiofrequency (RF) transmission in MRI by real-time monitoring of signal phase and amplitude. METHODS: Monitoring was carried out with a 4-channel prototype system by sensing, down sampling, digitizing, and optically transmitting the RF transmit signal to a remote PC to control the amplifiers. Performance was evaluated with benchtop and 7 T MRI experiments...
September 14, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28895021/k-band-doppler-radar-for-contact-less-overnight-sleep-marker-assessment-a-pilot-validation-study
#12
Rakesh Vasireddy, Corinne Roth, Johannes Mathis, Josef Goette, Marcel Jacomet, Andreas Vogt
An estimated 45 million persons in Europe are annually subjected to sleep-wake disorders. State-of-the-art polysomnography provides sophisticated insights into sleep (patho)physiology. A drawback of the method, however, is the obtrusive setting dependent on a clinical-based sleep laboratory with high operational costs. A contact-less prototype was developed to monitor limb movements and vital signs during sleep. A dual channel K-band Doppler radar transceiver captured limb movements and periodic chest wall motion due to respiration and heart activity...
September 11, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28868212/high-density-mapping-of-brain-slices-using-a-large-multi-functional-high-density-cmos-microelectrode-array-system
#13
Vijay Viswam, Raziyeh Bounik, Amir Shadmani, Jelena Dragas, Marie Obien, Jan Müller, Yihui Chen, Andreas Hierlemann
We present a CMOS-based high-density microelectrode array (HD-MEA) system that enables high-density mapping of brain slices in-vitro with multiple readout modalities. The 4.48×2.43 mm(2) array consists of 59,760 micro-electrodes at 13.5 µm pitch (5487 electrodes/mm(2)). The overall system features 2048 action-potential, 32 local-field-potential and 32 current recording channels, 32 impedance-measurement and 28 neurotransmitter-detection channels and 16 voltage/current stimulation channels. The system enables real-time and label-free monitoring of position, size, morphology and electrical activity of brain slices...
June 2017: Int Solid State Sens Actuators Microsyst Conf
https://www.readbyqxmd.com/read/28863640/synchronous-acquisition-of-multi-channel-signals-by-single-channel-adc-based-on-square-wave-modulation
#14
Xiaoqing Yi, Liling Hao, Fangfang Jiang, Lisheng Xu, Shaoxiu Song, Gang Li, Ling Lin
Synchronous acquisition of multi-channel biopotential signals, such as electrocardiograph (ECG) and electroencephalograph, has vital significance in health care and clinical diagnosis. In this paper, we proposed a new method which is using single channel ADC to acquire multi-channel biopotential signals modulated by square waves synchronously. In this method, a specific modulate and demodulate method has been investigated without complex signal processing schemes. For each channel, the sampling rate would not decline with the increase of the number of signal channels...
August 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28829322/success-rate-and-technical-quality-of-home-polysomnography-with-self-applicable-electrode-set-in-subjects-with-possible-sleep-bruxism
#15
Tomi Miettinen, Katja Myllymaa, Susanna Westeren-Punnonen, Jari Ahlberg, Taina Hukkanen, Juha Toyras, Reijo Lappalainen, Esa Mervaala, Kirsi Sipila, Sami Myllymaa
Using sleep laboratory polysomnography (PSG) is restricted for the diagnosis of only the most severe sleep disorders due to its low availability and high cost. Home PSG is more affordable, but applying conventional electroencephalography (EEG) electrodes increases its overall complexity and lowers the availability. Simple, self-administered single-channel EEG monitors on the other hand suffer from poor reliability. In this study, we aimed to quantify the reliability of self-administrated home PSG recordings conducted with a newly designed ambulatory electrode set (AES) that enables multi-channel EEG, electrooculography, electromyography and electrocardiography recordings...
August 18, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28792054/droplet-trapping-and-fast-acoustic-release-in-a-multi-height-device-with-steady-state-flow
#16
Richard W Rambach, Kevin Linder, Michael Heymann, Thomas Franke
We demonstrate a novel multilayer polydimethylsiloxane (PDMS) device for selective storage and release of single emulsion droplets. Drops are captured in a microchannel cavity and can be released on-demand through a triggered surface acoustic wave pulse. The surface acoustic wave (SAW) is excited by a tapered interdigital transducer (TIDT) deposited on a piezoelectric lithium niobate (LiNbO3) substrate and inverts the pressure difference across the cavity trap to push a drop out of the trap and back into the main flow channel...
October 11, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28769775/measuring-mental-workload-with-eeg-fnirs
#17
Haleh Aghajani, Marc Garbey, Ahmet Omurtag
We studied the capability of a Hybrid functional neuroimaging technique to quantify human mental workload (MWL). We have used electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) as imaging modalities with 17 healthy subjects performing the letter n-back task, a standard experimental paradigm related to working memory (WM). The level of MWL was parametrically changed by variation of n from 0 to 3. Nineteen EEG channels were covering the whole-head and 19 fNIRS channels were located on the forehead to cover the most dominant brain region involved in WM...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28762503/mechanomyography-based-wearable-monitor-of-quasi-isometric-muscle-fatigue-for-motor-neural-prostheses
#18
Eddy Krueger, Lana Popović-Maneski, Percy Nohama
A motor neural prosthesis based on surface functional electrical stimulation (sFES) can restore functional movement (e.g., standing, walking) in patients with a spinal cord injury (SCI). sFES generates muscle contractions in antigravity muscles and allows balance-assisted standing. This induced standing has several benefits, such as improved cardiovascular function, decreased incidence of urinary infections, reduced joint contractures, and muscle atrophy. The duration of sFES assisted standing is limited due to the quick onset of muscle fatigue...
August 1, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28669190/temperature-and-size-dependence-of-characteristic-hydrogen-bonded-network-structures-with-ion-core-switching-in-protonated-methanol-6-10-water-1-mixed-clusters-a-revisit
#19
Marusu Katada, Po-Jen Hsu, Asuka Fujii, Jer-Lai Kuo
Hydrogen-bonded network structures and preferential ion core in the protonated methanol-water mixed clusters, H(+)(methanol)n-(water)1 (n = 6-10), were explored by a combination of infrared spectroscopy and theoretical calculations. Infrared spectra of the OH stretch region of the clusters were measured at the two different temperature ranges by using Ar-tagging. Stable isomer structures of the clusters were searched by the multiscale modeling approach and temperature dependent infrared spectra were simulated based on the statistical populations of the isomers...
July 27, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28633068/multi-electrode-system-for-measurement-of-transmembrane-ion-fluxes-through-living-epithelial-cells
#20
Mirosław Zając, Andrzej Lewenstam, Krzysztof Dolowy
Cystic Fibrosis (CF) is the most common fatal human genetic disease. It is caused by the defect in a single anion channel protein which affects ion and water transport across the epithelial tissue. A flat multi-electrode platform of diameter 12mm, allowing for measurement of four ions: sodium, potassium, hydrogen and chloride by exchangeable/replaceable ion-selective electrodes is described. The measurement is possible owing to the architecture of the platform which accommodates all the electrodes and inlets/outlets...
October 2017: Bioelectrochemistry
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