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Post-stroke Depression

Ling-Feng Zeng, Ye Cao, Lu Wang, Yun-Kai Dai, Ling Hu, Qi Wang, Li-Ting Zhu, Wen-Hu Bao, Yuan-Ping Zou, Yun-Bo Chen, Wei-Hua Xu, Wei-Xiong Liang, Ning-Sheng Wang
Current evidence demonstrated certain beneficial effects of medicinal herbs as an adjuvant therapy for post-stroke depression (PSD) in China; Chai-hu (Chinese Thorowax Root, Radix Bupleuri) is an example of a medicinal plant for Liver-Qi regulation (MPLR) in the treatment of PSD. Despite several narrative reports on the antidepressant properties of MPLR, it appears that there are no systematic reviews to summarize its outcome effects. Therefore, the aim of this review was to assess the effectiveness and safety of MPLR adjuvant therapy in patients with PSD...
October 20, 2016: Phytotherapy Research: PTR
Michitaka Funayama, Motoichiro Kato, Masaru Mimura
BACKGROUND: Although post-stroke depression is a well-characterized disorder, there is less understanding of how pre-existence of depression is affected by a stroke. CASE PRESENTATION: We describe a patient with treatment-resistant major depression, which had been ongoing for 14 years but disappeared shortly after onset of a subarachnoid hemorrhage. Her cognitive function and functional status were mostly unaffected by the stroke. However, she no longer excessively regretted past events...
October 19, 2016: BMC Neurology
Xiao-Fan Zhang, Wei Zou, Yuan Yang
Depression is an important post-stroke sequela with negative impact on mortality, functional outcome and quality of life. Changes in cytokines have been hypothesized to be associated with the etiology of post-stroke depression (PSD). The altere dhypothalamic-pituitary-adrenal (HPA) functioning is associated with the onset of depression. The activity of HPA could induce the fluctuations of cortisol levels. In this study, we prospectively checked interleukin 6 (IL-6) and cortisol levels in patients with early ischemic stroke...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
Michael R Hamblin
Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has either been injured, is degenerating, or else is at risk of dying. One of the organ systems of the human body that is most necessary to life, and whose optimum functioning is most worried about by humankind in general, is the brain. The brain suffers from many different disorders that can be classified into three broad groupings: traumatic events (stroke, traumatic brain injury, and global ischemia), degenerative diseases (dementia, Alzheimer's and Parkinson's), and psychiatric disorders (depression, anxiety, post traumatic stress disorder)...
December 2016: BBA Clinical
Roderick Wondergem, Martijn F Pisters, Eveline J Wouters, Nick Olthof, Rob A de Bie, Johanna M A Visser-Meily, Cindy Veenhof
BACKGROUND: Stroke is not only an acute disease, but for the majority of patients, it also becomes a chronic condition. There is a major concern about the long-term follow-up with respect to activities of daily living (ADL) in stroke survivors. Some patients seem to be at risk for decline after a first-ever stroke. The purpose of this study was to determine the course of ADL from 3 months after the first-ever stroke and onward and identify factors associated with decline in ADL. METHODS: A systematic literature search of 3 electronic databases through June 2015 was conducted...
October 18, 2016: Cerebrovascular Diseases
Jéssica Elias Vicentini, Marina Weiler, Sara Regina Meira Almeida, Brunno Machado de Campos, Lenise Valler, Li Min Li
Depression and anxiety symptoms are common after stroke and associated to reduction in quality of life and poor physical and social outcomes. The Default Mode Network (DMN) plays an important role in the emotional processing. We investigated whether these symptoms are associated to a disruption of DMN functional connectivity in the first month after stroke. Thirty-four subacute ischemic stroke patients were submitted to: 1) behavioral assessment through Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Structured Clinical Interview for DSM Disorders; 2) neuropsychological assessment using Mini Mental State Examination and Montreal Cognitive Assessment; 3) resting state functional magnetic resonance imaging acquisition using a 3 T scanner (Philips Achieva)...
October 14, 2016: Brain Imaging and Behavior
Jong S Kim
Post-stroke mood and emotional disturbances are frequent and diverse in their manifestations. Out of the many post-stroke disturbances, post-stroke depression, post-stroke anxiety, post-stroke emotional incontinence, post-stroke anger proneness, and post-stroke fatigue are frequent and important symptoms. These symptoms are distressing for both the patients and their caregivers, and negatively influence the patient's quality of life. Unfortunately, these emotional disturbances are not apparent and are therefore often unnoticed by busy clinicians...
September 2016: Journal of Stroke
Andoret van Wyk, Carina A Eksteen, Piet J Becker, Barbara M Heinze
INTRODUCTION: Visual impairment, specifically eye movement disorders and vestibular dysfunction may have a negative influence on the functional recovery in post-stroke patients. This type of sensory dysfunction may further be associated with poor functional outcome in patients' post-stroke. METHODS: In phase 1, a cross-sectional survey (n = 100) will be conducted to determine the prevalence of eye movement disorders and vestibular dysfunction in patients who sustained a stroke...
2016: Frontiers in Neurology
Toby B Cumming, Marcie Packer, Sharon F Kramer, Coralie English
BACKGROUND: Fatigue is a common and debilitating symptom after stroke. The last decade has seen rapid expansion of the research literature on post-stroke fatigue, but prevalence remains unclear. AIMS: To estimate post-stroke fatigue prevalence and to identify the contributing factors to fatigue, by conducting a systematic review and meta-analysis. SUMMARY OF REVIEW: We included all studies of adult stroke survivors that used a recognized assessment scale for fatigue (search date September 2014)...
October 4, 2016: International Journal of Stroke: Official Journal of the International Stroke Society
Liping Wang, Huiqin Xu, Wenwei Ren, Lin Zhu, Yaling Chang, Yingying Gu, Mengjiao Yan, Jincai He
Previous studies have shown that prealbumin is associated with depression. However, the association between prealbumin and post-stroke depression remains unelucidated. This observational cohort study determined whether low baseline serum prealbumin could predict post-stroke depression at 1 month in patients admitted with acute stroke. The study, conducted from October 2013 to September 2014, included 307 patients with acute stroke who were followed-up for 1 month. Serum prealbumin was measured within 24h after admission using an immunoturbidimetric method...
September 15, 2016: Psychiatry Research
Chieh Grace Lau, Wai Kwong Tang, Xiang Xin Liu, Hua Jun Liang, Yan Liang, Vincent Mok, Adrian Wong, Gabor S Ungvari, Mansur A Kutlubaev, Ka Sing Wong
OBJECTIVE: To examine the relationship between neuroticism and fatigue in Chinese stroke patients. DESIGN: Cross-sectional. SETTING: PARTICIPANTS: One hundred and ninety-one ischemic stroke survivors recruited from the above-mentioned acute stroke unit between May 2010 and September 2011. INTERVENTIONS: None. MAIN OUTCOME MEASURES: The personality trait of neuroticism was measured with the neuroticism subscale of the Chinese version of the NEO-five-factor Inventory (NEO-FFI)...
September 24, 2016: Archives of Physical Medicine and Rehabilitation
Siham Zahi, Laila Mahir, Herman Azanmasso, Fatima Lmidmani, Abdellatif El Fatimi
OBJECTIVE: Depression affects many people following their stroke (between 30 and 60%). It can occur in the days following the attack but several years later. Our objective was to investigate the incidence of depression and anxiety in our patients after stroke followed for post-stroke hemiplegia. MATERIAL/PATIENTS AND METHODS: Prospective study over 6 months from 10 September 2014 to 10 March 2015. It covered all cases of stroke supported the MPR service during this period were excluded patients with severe aphasia...
September 2016: Annals of Physical and Rehabilitation Medicine
Ngor Side Diagne, Massaman Camara, Abou Sy, Ousmane Cissé, Amadou Koura Ndao, Amadou Gallo Diop, Mouhamadou Mansour Ndiaye
OBJECTIVE: Therefore, the aim of our study was to determine risk factors for poor quality of life by considering disability after stroke in its multidimensional aspects but also to see the impact of each risk factor on the dimensions of quality of life. MATERIAL/PATIENTS AND METHODS: A prospective study of stroke patients confirmed, followed by neurovascular consultation at Fann Hospital in Dakar has been achieved. Quality of life was evaluated by the 65 Sikness Impact Profile (SIP 65), the depression by the scale of Beck...
September 2016: Annals of Physical and Rehabilitation Medicine
David Chaparro, Justine Lacroix, Benoit Borel, Jean-Yves Salle, Benjamin Kammoun, Jean-Christophe Daviet, Stéphane Mandigout
OBJECTIVE: Physical activity (PA) and exercise are two successful approaches to reduce sedentary behavior and risk managing in stroke patients. The aims of the study are to evaluate PA and physical inactivity levels in post-stroke patients and to correlate PA parameters with gait performance, fatigue, anxiety, and anthropometry parameters in subacute phase of stroke recovery. MATERIAL/PATIENTS AND METHODS: Preliminary analysis of 24 patients in PA incitation program (mean age: 61...
September 2016: Annals of Physical and Rehabilitation Medicine
Marjorie Kerzoncuf, Laurent Bensoussan, Jean Michel Viton, Alain Delarque, Christiane Rossi Durand
OBJECTIVE: The therapeutic effects of intramuscular injections of botulinum toxin-type A on spasticity can be largely explained by its blocking action at the neuromuscular junction. BTx-A is assumed also to have a central action by affecting the functional organization of the CNS. The objective was to assess its action on spinal motor networks by investigating the post-activation depression (post-AD) of the soleus H-reflex in post-stroke patients. Post-AD that is a presynaptic mechanism controlling the synaptic efficacy of Ia-motoneuron transmission is involved in the pathophysiology of spasticity...
September 2016: Annals of Physical and Rehabilitation Medicine
Kerry Louise Hanna, Lauren Rachel Hepworth, Fiona Rowe
PURPOSE: To provide a systematic overview of the various tools available to screen for post-stroke visual impairment. METHODS: A review of the literature was conducted including randomised controlled trials, controlled trials, cohort studies, observational studies, systematic reviews and retrospective medical note reviews. All languages were included and translation was obtained. Participants included adults ≥18 years old diagnosed with a visual impairment as a direct cause of a stroke...
September 26, 2016: Disability and Rehabilitation
N Charfi, S Trabelsi, M Turki, M Mâalej Bouali, L Zouari, M Dammak, J Ben Thabet, C Mhiri, M Mâalej
INTRODUCTION: The physical and/or psycho-cognitive changes after stroke may lead to a decline in the quality of life (QOL) of patients. The aims of our study were to evaluate the QOL of stroke survivors and to investigate its relationships with the physical disability degree and the emotional disorders (anxiety and depression). METHODS: We conducted a cross-sectional study, which included 147 patients, followed for stroke that had occurred over the past year, in the outpatient neurology department at the university hospital Habib Bourguiba of Sfax (Tunisia)...
September 20, 2016: L'Encéphale
Karla Bustamante Valles, Sandra Montes, Maria de Jesus Madrigal, Adan Burciaga, María Elena Martínez, Michelle J Johnson
BACKGROUND: Stroke rehabilitation in low- and middle-income countries, such as Mexico, is often hampered by lack of clinical resources and funding. To provide a cost-effective solution for comprehensive post-stroke rehabilitation that can alleviate the need for one-on-one physical or occupational therapy, in lower and upper extremities, we proposed and implemented a technology-assisted rehabilitation gymnasium in Chihuahua, Mexico. The Gymnasium for Robotic Rehabilitation (Robot Gym) consisted of low- and high-tech systems for upper and lower limb rehabilitation...
2016: Journal of Neuroengineering and Rehabilitation
Kenji Tsuchiya, Takaaki Fujita, Daisuke Sato, Manabu Midorikawa, Yasushi Makiyama, Kaori Shimoda, Fusae Tozato
[Purpose] There have been no investigations into the improvement of activities of daily living among patients suffering from post-stroke depression on admission to convalescent rehabilitation wards in Japan. This study aimed to assess the improvement of activities in daily living in patients with or without post-stroke depression at the time of admission to a convalescent rehabilitation ward. [Subjects and Methods] This retrospective study included 108 stroke patients divided into two groups according to their Geriatric Depression Scale 15-item short form scores...
August 2016: Journal of Physical Therapy Science
Kurt A Mossberg, William J Durham, Dennis J Zgaljardic, Charles R Gilkison, Christopher P Danesi, Melinda Sheffield-Moore, Brent E Masel, Randall J Urban
We explored the effects of recombinant human growth hormone (rhGH) replacement on physical and cognitive functioning in subjects with a moderate-to-severe traumatic brain injury (TBI) with abnormal growth hormone (GH) secretion. Fifteen individuals who sustained a TBI at least 12 months prior to study enrollment were identified as having abnormal GH secretion by glucagon stimulation testing (maximum GH response less than 8 ng/mL). Peak cardiorespiratory capacity, body composition, and muscle force testing were assessed at baseline and one year after rhGH replacement...
October 13, 2016: Journal of Neurotrauma
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