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Post-stroke Depression

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https://www.readbyqxmd.com/read/29149884/predictors-of-early-onset-post-ischemic-stroke-depression-a-cross-sectional-study
#1
Guilin Meng, Xiaoye Ma, Lei Li, Yan Tan, Xiaohui Liu, Xueyuan Liu, Yanxin Zhao
BACKGROUND: Post-stroke depression (PSD) seriously affects the rehabilitation of nerve function and quality of life. However, the pathogenesis of PSD is still not clear. This study aimed to investigate the demographic, clinical, and biochemical factors in patients with PSD. METHODS: Patients with an acute ischemic stroke, who met the inclusion criteria at Shanghai Tenth People's Hospital from April 2016 to September 2016, were recruited for this study. The stroke severity was assessed using the National Institutes of Health Stroke Scale (NIHSS), and the mental state was assessed using Mini-Mental State Examination (MMSE), Hamilton Depression Scale (HAMD), and Hamilton Anxiety Scale (HAMA) at 1 week of admission...
November 17, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29146661/what-is-the-relationship-between-physical-activity-and-cardiovascular-risk-factors-in-stroke-survivors-post-completion-of-rehabilitation-protocol-for-a-longitudinal-study
#2
Natalie A Fini, Julie Bernhardt, Anne E Holland
INTRODUCTION: Physical activity (PA) can modify cardiovascular and other health risks in people with stroke, but we know little about long-term PA in this group. This study aims to describe PA levels and investigate relationships between PA, cardiovascular risk factors, mobility and participant characteristics (eg, age, mood and fatigue) in the 2 years following rehabilitation discharge after first stroke. METHODS AND ANALYSIS: This is a longitudinal observational study with follow-up at 6, 12 and 24 months after rehabilitation discharge...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29135285/factors-associated-with-confidence-in-decision-making-and-satisfaction-with-risk-communication-among-patients-with-atrial-fibrillation
#3
Berith Hedberg, Dan Malm, Jan-Erik Karlsson, Kristofer Årestedt, Anders Broström
BACKGROUND: Atrial fibrillation is a prevalent cardiac arrhythmia. Effective communication of risks (e.g. stroke risk) and benefits of treatment (e.g. oral anticoagulants) is crucial for the process of shared decision making. AIM: The aim of this study was to explore factors associated with confidence in decision making and satisfaction with risk communication after a follow-up visit among patients who three months earlier had visited an emergency room for atrial fibrillation related symptoms...
November 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29128343/post-stroke-depression-mechanisms-and-pharmacological-treatment
#4
REVIEW
Roberto Federico Villa, Federica Ferrari, Antonio Moretti
Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively affects survivals' functional outcome, response to rehabilitation and quality of life. Approximately, one-third of them are affected by post-stroke depression (PSD), making it a serious social and public health problem and anti-depressant preventive and curative therapies worth investigating. However, a two-way association between depression and stroke has been also established: stroke increases the risk of PSD, but depression is an independent risk factor for stroke...
November 8, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29127758/-physical-activity-the-holy-grail-of-modern-medicine
#5
Vladimír Tuka, Martina Daňková, Karel Riegel, Martin Matoulek
Movement is the basic attribute of life. It is not surprising that the return to regular physical activity is a very effective and cheap means of preventing and treating most non-cummunicable diseases. Therefore, every physician should be able to prescribe a suitable physical activity. The minimum amount of physical activity with proven effects in primary prevention of chronic diseases is relatively low: 150 minutes of moderate physical activity or 75 minutes of high intensity exercise per week or a combination of the two...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29127269/intracerebral-hemorrhage-and-outcome-after-thrombolysis-in-stroke-patients-using-selective-serotonin-reuptake-inhibitors
#6
Jan F Scheitz, Guillaume Turc, Linda Kujala, Alexandros A Polymeris, Mirjam R Heldner, Thomas P Zonneveld, Hebun Erdur, Sami Curtze, Christopher Traenka, Céline Brenière, Roland Wiest, Andrea Rocco, Gerli Sibolt, Henrik Gensicke, Matthias Endres, Nicolas Martinez-Majander, Yannick Béjot, Paul J Nederkoorn, Catherine Oppenheim, Marcel Arnold, Stefan T Engelter, Daniel Strbian, Christian H Nolte
BACKGROUND AND PURPOSE: Selective serotonin-reuptake inhibitors (SSRIs) impair platelet function and have been linked to a higher risk of spontaneous intracerebral hemorrhage-an association that may be augmented by oral anticoagulants (OAC). We aimed to assess whether preadmission treatment with SSRIs in patients with acute ischemic stroke is associated with post-thrombolysis symptomatic intracerebral hemorrhage (sICH) and functional outcome. METHODS: A multicenter retrospective analysis was conducted in prospective registries of patients treated by thrombolysis within 4...
November 10, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29116947/cerebrovascular-steal-phenomenon-and-electroconvulsive-therapy-a-case-report-and-review-of-the-literature
#7
Ana Hategan, Calvin H Hirsch
Electroconvulsive therapy (ECT) is a safe and effective treatment for major depressive disorder, but cerebrovascular and cardiovascular complications, although rare, remain the most concerning. This is particularly notable in those with preexisting cerebrovascular disease, which impacts dynamic cerebral autoregulation. In these patients, the increased blood flow to the seizing portions of the brain induced by ECT potentially can reduce cerebral blood flow to ischemic areas, possibly causing adverse neurological events...
November 8, 2017: Journal of ECT
https://www.readbyqxmd.com/read/29107039/perceived-participation-and-its-correlates-among-first-stroke-survivors-at-six-months-after-discharge-from-a-tertiary-hospital-in-china
#8
Xuemei Chen, Yanan He, Xianmei Meng, Chenchen Gao, Zhihui Liu, Lanshu Zhou
OBJECTIVES: To describe perceived participation of first-stroke survivors in mainland China, and to determine variables that may correlate with perceived participation six months after discharge. DESIGN: Cross-sectional survey. SETTING: Neurology department of a tertiary hospital in Shanghai, China, with subsequent follow-up of patients in their homes. SUBJECTS: Two hundred and thirty-six first-stroke survivors who had been treated in the neurology department and discharged six months prior to their participation in our study...
October 26, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29097744/alleviative-effects-of-fluoxetine-on-depressive-like-behaviors-by-epigenetic-regulation-of-bdnf-gene-transcription-in-mouse-model-of-post-stroke-depression
#9
Hui-Juan Jin, Lei Pei, Ya-Nan Li, Hui Zheng, Shuai Yang, Yan Wan, Ling Mao, Yuan-Peng Xia, Quan-Wei He, Man Li, Zhen-Yu Yue, Bo Hu
Fluoxetine, one of the selective serotonin reuptake inhibitor (SSRI) antidepressants, has been thought to be effective for treating post-stroke depression (PSD). Recent work has shown that fluoxetine may exert an antidepressive effect through increasing the level of brain-derived neurotrophic factor (BDNF), but the underlying mechanism still remains unclear. In the present study, we successfully established the PSD model using male C57BL/6 J mice by photothrombosis of the left anterior cortex combined with isolatied-housing conditions...
November 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29093543/a-study-of-the-brain-functional-network-of-post-stroke-depression-in-three-different-lesion-locations
#10
Yu Shi, Yanyan Zeng, Lei Wu, Ziping Liu, Shanshan Zhang, Jianming Yang, Wen Wu
Research on the mechanism of post stroke depression (PSD) is the key way to improve the treatment of PSD. However, the functional brain network of PSD has not been entirely supported by the results of functional magnetic resonance imaging (fMRI) studies. The aims of this study are to investigate the brain response of PSD in three different lesions. The brain responses of the three PSD subgroups were similar. However, each subgroup had its own characteristics of the brain network. In the temporal lobe subgroup, the right thalamus had increased degree centrality (DC) values which were different from the other two subgroups...
November 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29078742/a-single-session-of-moderate-intensity-walking-increases-brain-derived-neurotrophic-factor-bdnf-in-the-chronic-post-stroke-patients
#11
Viviane Aparecida Carvalho de Morais, Marina Ferreira da Silva Tourino, Ana Carolina de Souza Almeida, Thaís Bueno Dias Albuquerque, Roberta Castro Linhares, Paulo Pereira Christo, Patrícia Massara Martinelli, Paula Luciana Scalzo
Background Aerobic exercise, even for short durations, may promote an increase in serum concentrations of brain-derived neurotrophic factor (BDNF). However, it is necessary to determine the optimal exercise types and intensities to increase BDNF levels. Objectives This aim of this study was investigate the effects of mild and moderate intensity acute aerobic exercise on serum BDNF levels in patients in the chronic post-stroke phase. Methods The participants answered a socio-demographic questionnaire, cognitive assessment (Mini Mental State Examination), assessment of depressive symptoms (Hamilton Depression Scale), fatigue (Fatigue Severity Scale) and functional capacity (6-minute walk test)...
October 27, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29075345/factors-that-influence-the-severity-of-post-stroke-depression
#12
S Ilut, A Stan, A Blesneag, V Vacaras, S Vesa, L Fodoreanu
AIM: The aim of this paper was to investigate whether the extent of neurological impairment, the location of ischemic lesions due to stroke are associated with the severity of post-stroke depression. MATERIALS AND METHODS: The study included 82 patients, who were diagnosed with acute ischemic stroke and post-stroke depression and were admitted to the Neurology Clinic of Cluj-Napoca County Emergency Hospital between 2009 and 2011. A head MRI was performed with a 1...
July 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/29071896/-effect-of-manual-acupuncture-intervention-on-levels-of-5-htt-5-ht1ar-ne%C3%AE-2r-of-brain-tissues-in-rats-with-post-stroke-depression
#13
Wei Xiao, Xian-Bao Zhang, Zhen Wang, Yan Wang, Xiao-Li Guo, Ling He, Fa-Jun Liang, Hui-Xing Hu
OBJECTIVE: To observe the effect of manual acupuncture intervention on serotonin transporter (5-HTT), 5-HT 1 A receptor (5-HT1AR), norepinephrine (NE) alpha receptor 2 (NEα2R) protein of brain tissues in rats with post-stroke depression (PSD). METHODS: Forty SD rats were randomly divided into normal group, model group, medication group and acupuncture group, with 10 rats in each. The PSD model was established by the combination of middle cerebral artery occlusion and chronic non- predictable mild stress...
December 25, 2016: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29067724/diabetes-training-for-community-health-workers-on-an-american-indian-reservation
#14
Judith M Policicchio, Katherine Dontje
OBJECTIVES: To improve the knowledge and skills of community health workers (CHWs) on an American Indian (AI) Reservation related to the management of diabetes to allow CHWs, with no prior formal diabetes education to work more effectively with individuals in the community with diabetes. Training was provided in six "face-to-face" sessions with the CHWs using the Centers for Disease Control and Prevention CHW Training Resource on Heart Disease and Stroke. DESIGN AND SAMPLE: This is a quality improvement program guided by the Model for Improvement: Plan, Do, Study, Act and using a pre-post evaluation design...
October 24, 2017: Public Health Nursing
https://www.readbyqxmd.com/read/29057699/management-of-post-stroke-mood-and-emotional-disturbances
#15
Jong S Kim
Mood and emotional disturbances are common in stroke patients. Out of diverse post-stroke emotional disturbances, depression, anxiety, emotional incontinence, anger proneness, and fatigue are frequent and important symptoms. These symptoms are distressing for both the patients and their caregivers, and negatively influence the patient's quality of life. The emotional symptoms are not apparent and are therefore often neglected by neurologists. Their phenomenology, predicting factors, and pathophysiology have been under-studied, and are under-recognized...
October 26, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29056502/factors-associated-with-post-stroke-physical-activity-a-systematic-review-and-meta-analysis
#16
REVIEW
Shamala Thilarajah, Benjamin F Mentiplay, Kelly J Bower, Dawn Tan, Pua Yong Hao, Gavin Williams, Gerald Koh, Ross A Clark
OBJECTIVE: To integrate the literature investigating factors associated with post-stroke physical activity. DATA SOURCES: A search was conducted from database inception to June 2016 across nine databases: Cochrane, Medline, ProQuest, Web of Science ISI, PsycInfo, Scopus, Embase, CINAHL and AMED. The reference lists of included articles were screened for secondary literature. STUDY SELECTION: Cohort and cross-sectional studies were included if they recruited community-dwelling stroke survivors and measured factors associated with physical activity...
October 19, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29051732/age-related-frontal-periventricular-white-matter-hyperintensities-and-mir-92a-3p-are-associated-with-early-onset-post-stroke-depression
#17
Ji-Rong He, Yu Zhang, Wen-Jing Lu, Huai-Bin Liang, Xuan-Qiang Tu, Fei-Yue Ma, Guo-Yuan Yang, Li-Li Zeng
Objective: To explore the correlationship among white matter hyperintensities (WMHs), miR-92a-3p and early-onset post-stroke depression (PSD). Methods: We recruited consecutively 238 patients with acute cerebral infarction and MRI examination in the Department of neurology, Ruijin hospital, Shanghai Jiaotong University School of Medicine. The diagnosis of early-onset PSD was made in accordance with DSM-IV criteria for depression in 2 weeks after stroke. Clinical information and assessments of stroke severity were recorded on admission...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29044603/comorbid-masticatory-impairment-delays-recovery-from-acute-cerebral-ischemia-and-locomotor-hypoactivity-after-subarachnoid-hemorrhage-in-mice
#18
Ikuho Kojima, Tatsushi Mutoh, Kazumasu Sasaki, Yasuko Tatewaki, Yasuyuki Taki, Tatsuya Ishikawa
Tooth loss and related changes in the functionality may lead to worse outcome of stroke patients, but the link involved in this pathway remains unclear. This study aimed to determine the effect of comorbid masticatory impairment on acute cerebral ischemia and neurobehavioral outcome after experimental subarachnoid hemorrhage (SAH). Thirty C57BL/6 mice with (molar-less) or without (control) prior treatment of cutting off the upper molars (separated by at least one week), were subjected to SAH by endovascular perforation...
October 17, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29038494/a-study-of-the-brain-abnormalities-of-post-stroke-depression-in-frontal-lobe-lesion
#19
Yu Shi, Yanyan Zeng, Lei Wu, Wei Liu, Ziping Liu, Shanshan Zhang, Jianming Yang, Wen Wu
Post stroke depression (PSD) is a serious complication of stroke. Brain imaging is an important method of studying the mechanism of PSD. However, few studies have focused on the single lesion location. The aim of this study was to investigate the brain mechanism of frontal lobe PSD using combined voxel-based morphometry (VBM) and functional magnetic resonance imaging (fMRI). In total, 30 first-time ischemic frontal lobe stroke patients underwent T1 weighted MRI and resting-state fMRI scans. Clinical assessments included the 24-item Hamilton Rating Scale for Depression, the National Institutes of Health Stroke Scale, and the Mini-Mental State Examination...
October 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29035724/factors-associated-with-post-stroke-suicidal-death
#20
Jin Pyo Hong, Subin Park, Sung-Ho Ahn, Jong S Kim
BACKGROUND AND PURPOSE: The aim of this study was to estimate the relative risk of suicidal death compared to the general population and to identify risk factors for suicidal death among stroke patients. METHODS: Our sample consisted of 7175 patients who were diagnosed with stroke and admitted at Asan Medical Center from January 2005 to December 2012. Information on suicidal death was obtained from the database of the Korean National Statistical Office. The standardized mortality ratio (SMR) for post-stroke suicide was estimated...
October 7, 2017: Journal of Psychiatric Research
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