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https://www.readbyqxmd.com/read/28098529/multidrug-resistant-candida-haemulonii-and-c-auris-tel-aviv-israel
#1
Ronen Ben-Ami, Judith Berman, Ana Novikov, Edna Bash, Yael Shachor-Meyouhas, Shiri Zakin, Yasmin Maor, Jalal Tarabia, Vered Schechner, Amos Adler, Talya Finn
Candida auris and C. haemulonii are closely related, multidrug-resistant emerging fungal pathogens that are not readily distinguishable with phenotypic assays. We studied C. auris and C. haemulonii clinical isolates from 2 hospitals in central Israel. C. auris was isolated in 5 patients with nosocomial bloodstream infection, and C. haemulonii was found as a colonizer of leg wounds at a peripheral vascular disease clinic. Liberal use of topical miconazole and close contact among patients were implicated in C...
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28080959/sentinel-surveillance-of-imported-dengue-via-travellers-to-europe-2012-to-2014-tropnet-data-from-the-denguetools-research-initiative
#2
Andreas Neumayr, Jose Muñoz, Mirjam Schunk, Emmanuel Bottieau, Jakob Cramer, Guido Calleri, Rogelio López-Vélez, Andrea Angheben, Thomas Zoller, Leo Visser, Núria Serre-Delcor, Blaise Genton, Francesco Castelli, Marjan Van Esbroeck, Alberto Matteelli, Laurence Rochat, Elena Sulleiro, Florian Kurth, Federico Gobbi, Francesca Norman, Ilaria Torta, Jan Clerinx, David Poluda, Miguel Martinez, Antonia Calvo-Cano, Maria Paz Sanchez-Seco, Annelies Wilder-Smith, Christoph Hatz, Leticia Franco
We describe the epidemiological pattern and genetic characteristics of 242 acute dengue infections imported to Europe by returning travellers from 2012 to 2014. The overall geographical pattern of imported dengue (South-east Asia > Americas > western Pacific region > Africa) remained stable compared with 1999 to 2010. We isolated the majority of dengue virus genotypes and epidemic lineages causing outbreaks and epidemics in Asia, America and Africa during the study period. Travellers acted as sentinels for four unusual dengue outbreaks (Madeira, 2012-13; Luanda, 2013; Dar es Salaam, 2014; Tokyo, 2014)...
January 5, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28066900/boosting-of-post-exposure-human-t-and-b-cell-recall-responses-in-vivo-by-burkholderia-pseudomallei-related-proteins
#3
Arnone Nithichanon, Louise J Gourlay, Gregory J Bancroft, Manabu Ato, Yoshimasa Takahashi, Ganjana Lertmemongkolchai
Burkholderia pseudomallei is the causative agent of melioidosis, an infectious disease with high incidence and mortality in South East Asia and Northern Australia. To date there is no protective vaccine and antibiotic treatment is prolonged and not always effective. Most people living in endemic areas have been exposed to the bacteria and have developed some immunity, which may have helped prevent disease. Here, we used a humanized mouse model (hu-PBL-SCID), reconstituted with human peripheral blood mononuclear cells (PBMCs) from seropositive donors, to illustrate the potential of three known antigens (FliC, OmpA and N-PilO2) for boosting both T- and B-cell immune responses...
January 9, 2017: Immunology
https://www.readbyqxmd.com/read/28060851/molecular-evidence-of-transmission-of-influenza-a-h1n1-2009-on-a-university-campus
#4
Ramandeep Kaur Virk, Vithiagaran Gunalan, Hong Kai Lee, Masafumi Inoue, Catherine Chua, Boon-Huan Tan, Paul Anantharajah Tambyah
BACKGROUND: In the recent years, the data on the molecular epidemiology of influenza viruses have expanded enormously because of the availability of cutting-edge sequencing technologies. However, much of the information is from the temperate regions with few studies from tropical regions such as South-east Asia. Despite the fact that influenza has been known to transmit rapidly within semi-closed communities, such as military camps and educational institutions, data are limited from these communities...
2017: PloS One
https://www.readbyqxmd.com/read/28060559/understanding-the-interaction-between-henipaviruses-and-their-natural-host-fruit-bats-paving-the-way-toward-control-of-highly-lethal-infection-in-humans
#5
François Enchéry, Branka Horvat
Hendra virus and Nipah virus (NiV) are highly pathogenic zoonotic paramyxoviruses, from henipavirus genus, that have emerged in late 1990s in Australia and South-East Asia, respectively. Since their initial identification, numerous outbreaks have been reported, affecting both domestic animals and humans, and multiple rounds of person-to-person NiV transmission were observed. Widely distributed fruit bats from Pteropodidae family were found to be henipavirus natural reservoir. Numerous studies have reported henipavirus seropositivity in pteropid bats, including bats in Africa, thus expanding notably the geographic distribution of these viruses...
January 6, 2017: International Reviews of Immunology
https://www.readbyqxmd.com/read/28056216/nuclear-localization-and-secretion-competence-is-conserved-amongst-henipavirus-matrix-proteins
#6
Elisabeth C McLinton, Kylie M Wagstaff, Alexander Lee, Gregory W Moseley, Glenn A Marsh, Lin-Fa Wang, David A Jans, Kim G Lieu, Hans Netter
Viruses of the genus Henipavirus of the family Paramyxoviridae are zoonotic pathogens, which have emerged in South East Asia, Australia and Africa. Nipah virus (NiV) and Hendra virus (HeV) are highly virulent pathogens transmitted from bats to animals and humans, whilst the henipavirus Cedar virus (CedV) seems to be non-pathogenic in infection studies. The full replication cycle of the Paramyxoviridae occurs in the host cell's cytoplasm where viral assembly is orchestrated by the matrix (M) protein. Unexpectedly, the NiV-M protein traffics through the nucleus as an essential step to engage the plasma membrane in preparation for viral budding/release...
January 5, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28053106/grp78-is-an-important-host-factor-for-japanese-encephalitis-virus-entry-and-replication-in-mammalian-cells
#7
Minu Nain, Sriparna Mukherjee, Sonali Porey Karmakar, Adrienne W Paton, James C Paton, M Z Abdin, Anirban Basu, Manjula Kalia, Sudhanshu Vrati
: Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is the leading cause of viral encephalitis in South-East Asia with potential to become a global pathogen. Here we identify the Glucose regulated protein 78 (GRP78) as an important host protein for virus entry and replication. Using the plasma membrane fractions from mouse neuronal (Neuro2a) cells, mass spectroscopy analysis identified GRP78 as a protein interacting with recombinant JEV envelope protein domain III. GRP78 was found to express on the plasma membrane of Neuro2a, mouse primary neurons, and human epithelial Huh-7 cells...
January 4, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28050595/cervical-cancer-prevention-training-in-south-east-asian-lmics
#8
Joseph Soon-Yau Ng, Ida Ismail-Pratt
The Association of Southeast Asian Nations (ASEAN) is a confederation of 10 sovereign states occupying approximately 1.7 million square miles of Southeast Asia with an estimated population of just under 630 million. Southeast Asia continues to have one of the world's highest rates of cervical cancer-related death. Organised training in cervical cancer screening is essential but lacking in low to middle income countries (LMICs). Systematic training of local doctors is an essential part of an effective screening program and an effective strategy to reduce cervical cancer-related mortality...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28049516/genetic-clustering-and-polymorphism-of-the-merozoite-surface-protein-3-of-plasmodium-knowlesi-clinical-isolates-from-peninsular-malaysia
#9
Jeremy Ryan De Silva, Yee Ling Lau, Mun Yik Fong
BACKGROUND: The simian malaria parasite Plasmodium knowlesi has been reported to cause significant numbers of human infection in South East Asia. Its merozoite surface protein-3 (MSP3) is a protein that belongs to a multi-gene family of proteins first found in Plasmodium falciparum. Several studies have evaluated the potential of P. falciparum MSP3 as a potential vaccine candidate. However, to date no detailed studies have been carried out on P. knowlesi MSP3 gene (pkmsp3). The present study investigates the genetic diversity, and haplotypes groups of pkmsp3 in P...
January 3, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28048995/-a-city-for-the-elderly-research-into-new-technologies-in-singapore
#10
REVIEW
Fabien Clavier
A city-state located at the heart of South East Asia, Singapore is now facing an accelerated ageing of the population, resulting from a very good health care coverage and a very low birth rate. A team of researchers from the French National Centre for Scientific Research (CNRS) is exploring the use of new technologies to improve the quality of life of elderly people in towns and cities and anticipate their health risks.
January 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28046059/donor-financing-of-global-mental-health-1995-2015-an-assessment-of-trends-channels-and-alignment-with-the-disease-burden
#11
F J Charlson, J Dieleman, L Singh, H A Whiteford
BACKGROUND: A recent report by the Institute for Health Metrics and Evaluation (IHME) highlights that mental health receives little attention despite being a major cause of disease burden. This paper extends previous assessments of development assistance for mental health (DAMH) in two significant ways; first by contrasting DAMH against that for other disease categories, and second by benchmarking allocated development assistance against the core disease burden metric (disability-adjusted life year) as estimated by the Global Burden of Disease Studies...
2017: PloS One
https://www.readbyqxmd.com/read/28043020/management-of-childhood-diarrhea-by-healthcare-professionals-in-low-income-countries-an-integrative-review
#12
REVIEW
Ana F Diallo, Xiaomei Cong, Wendy A Henderson, Jacqueline McGrath
BACKGROUND: The significant drop in child mortality due to diarrhea has been primarily attributed to the use of oral rehydration solutions, continuous feeding and zinc supplementation. Nevertheless uptake of these interventions have been slow in developing countries and many children suffering from diarrhea are not receiving adequate care according to the World Health Organization recommended guidelines for the clinical management of childhood diarrhea. OBJECTIVES: The aim of this integrative review is to appraise healthcare professionals' management of childhood diarrhea in low-income countries...
September 1, 2016: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28040673/genome-origin-historical-hybridization-and-genetic-differentiation-in-anthosachne-australasica-triticeae-poaceae-inferred-from-chloroplast-rbcl-trnh-psba-and-nuclear-acc1-gene-sequences
#13
Li-Na Sha, Xing Fan, Xiao-Li Wang, Zhen-Zhen Dong, Jian Zeng, Hai-Qin Zhang, Hou-Yang Kang, Yi Wang, Jin-Qiu Liao, Yong-Hong Zhou
BACKGROUND AND AIMS: Anthosachne Steudel is a group of allopolyploid species that was derived from hexaploidization between the Asian StY genome Roegneria entity and the Australasia W genome Australopyrum species. Polyploidization and apomixis contribute to taxonomic complexity in Anthosachne Here, a study is presented on the phylogeny and evolutionary history of Anthosachne australasica The aims are to demonstrate the process of polyploidization events and to explore the differentiation patterns of the St genome following geographic isolation...
January 2017: Annals of Botany
https://www.readbyqxmd.com/read/28039799/adenovirus-vectored-foot-and-mouth-disease-vaccine-confers-early-and-full-protection-against-fmdv-o1-manisa-in-swine
#14
Ignacio Fernandez-Sainz, Gisselle N Medina, Elizabeth Ramirez-Medina, Marla J Koster, Marvin J Grubman, Teresa de Los Santos
A human adenovirus (Ad5) vectored foot-and-mouth disease virus (FMDV) O1-Manisa subunit vaccine (Ad5-O1Man) was engineered to deliver FMDV O1-Manisa capsid and capsid-processing proteins. Swine inoculated with Ad5-O1Man developed an FMDV-specific humoral response as compared to animals inoculated with an empty Ad5-vector. Vaccinated animals were completely protected against homologous challenge at 7 or 21 days post-vaccination. Potency studies exhibited a PD50 of about 10(7) pfu/animal while a dose of 4×10(7)pfu/animal fully protected swine against FMDV intradermal challenge...
December 28, 2016: Virology
https://www.readbyqxmd.com/read/28034594/awareness-of-tick-borne-disease-and-compliance-with-using-tick-preventive-products-of-dog-owners-in-hong-kong
#15
Maureen V Boost, Choi-Yin Tung, Claudia Hoi-Ki Ip, July Fung-Oi Man, Toni Wing-Tung Hui, Candy Fung-Yee Leung, Maggie Yuen-Wa Mak, Queeny Yuen, Margaret M O'Donoghue
Tick-borne disease in dogs is common in South-east Asia and includes babesiosis and ehrlichiosis. These diseases can be largely prevented by compliant use of tick preventive products. This study investigated knowledge of ticks and tick-borne disease and use of tick preventive agents by a large sample of dog owners in Hong Kong. A total of 492 valid questionnaires were completed by owners attending veterinary practices, approached by researchers at common dog-walking areas, or targeted via local social media sites for pet owners...
December 21, 2016: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28031800/functional-traits-determine-heterospecific-use-of-risk-related-social-information-in-forest-birds-of-tropical-south-east-asia
#16
Fangyuan Hua, Ding Li Yong, Muhammad Nazri Janra, Liza M Fitri, Dewi Prawiradilaga, Kathryn E Sieving
In birds and mammals, mobbing calls constitute an important form of social information that can attract numerous sympatric species to localized mobbing aggregations. While such a response is thought to reduce the future predation risk for responding species, there is surprisingly little empirical evidence to support this hypothesis. One way to test the link between predation risk reduction and mobbing attraction involves testing the relationship between species' attraction to mobbing calls and the functional traits that define their vulnerability to predation risk...
December 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28030339/intra-and-inter-species-genetic-variability-of-transferrin-receptor-gene-regions-in-trypanosoma-evansi-isolates-of-different-livestock-and-geographical-regions-of-india
#17
Souti Prasad Sarkhel, S K Gupta, Jyoti Kaushik, Jarnail Singh, Vijesh Kumar Saini, Sanjay Kumar, Rajender Kumar
Trypanosoma evansi, the aetiological agent of Surra affects a wide range of livestock and wild animals in India. In the present study, we studied intra- and inter species genetic variability in the transferrin receptor encoding gene regions (ESAG6/7 gene region) of T. evansi isolates by cloning, sequencing and phylogenetic study collected from camel, cattle, donkeys and ponies from North-Western and Central India. The nucleotide sequence variation of ESAG6/7 gene region between Indian T. evansi isolates was up to 17...
March 1, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/28029573/mechanical-circulatory-support-and-heart-transplantation-in-the-asia-pacific-region
#18
EDITORIAL
Cumaraswamy Sivathasan, Choon Pin Lim, Ka Lee Kerk, David K L Sim, Mandeep R Mehra
Globalization has resulted in epidemiologic transition in developing countries from infectious disease and nutritional deficiencies to non-communicable diseases. Epidemiologic data on heart failure (HF), particularly advanced HF therapy, in Asia are increasingly becoming available, although they remain sparse. Heart transplantation for advanced stage HF remains very low in Asia-approximately 0.075 heart transplants per 1 million population. North America, which comprises 7.5% of the world population, accounted for 55...
September 29, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28028434/infection-prevention-and-control-of-clostridium-difficile-a-global-review-of-guidelines-strategies-and-recommendations
#19
Evelyn Balsells, Teodora Filipescu, Moe H Kyaw, Camilla Wiuff, Harry Campbell, Harish Nair
BACKGROUND: Clostridium difficile is the leading cause of health care-associated infections. Given the high incidence of C. difficile infection (CDI) and the lack of primary prevention through immunization, health care professionals should be aware of the most current guidance, as well as strengths and limitations of the evidence base underpinning this guidance. METHODS: We identified publicly available national or organizational guidelines related to CDI infection and prevention control (IPC) published between 2000 and 2015 and for any health care setting through an internet search using the Google search engine...
December 2016: Journal of Global Health
https://www.readbyqxmd.com/read/28028293/potential-use-of-cord-blood-for-hb-e-hemoglobinopathy-screening-programme-using-capillary-electrophoresis
#20
W A Wan Mohd Saman, R Hassan, S Mohd Yusoff, C A Che Yaakob, N A F Abdullah, S Ghazali, M A R Mohd Radzi, R Bahar
BACKGROUND: Thalassemia and hemoglobinopathies are inherited red blood cell disorders found worldwide. Hemoglobin (Hb) E disorder is one of the hemoglobinopathies known to have the high prevalence in South East Asia. Most of transfusion-dependent thalassemias were genotypically compound heterozygous Hb E/ β-thalassemia. In Malaysia, the national screening program for thalassemia was implemented for early pregnancy or secondary school girls; however many participants do not turn-up and missed the screening test...
December 2016: Malaysian Journal of Pathology
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