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https://www.readbyqxmd.com/read/28323563/isolation-of-an-h5n8-highly-pathogenic-avian-influenza-virus-strain-from-wild-birds-in-seoul-a-highly-urbanized-area-in-south-korea
#1
Jung-Hoon Kwon, Dong-Hun Lee, Jei-Hyun Jeong, Seong-Su Yuk, Tseren-Ochir Erdene-Ochir, Jin-Yong Noh, Woo-Tack Hong, Sol Jeong, Gyeong-Bin Gwon, Sang-Won Lee, In-Soo Choi, Chang-Seon Song
Asian-lineage H5 highly pathogenic avian influenza viruses (HPAIV) have caused recurrent outbreaks in poultry and wild birds. In January 2014, H5N8 HPAIV caused outbreaks in South Korea and subsequently spread to East Asia, Europe, and North America. We report the isolation of an H5N8 HPAIV strain from wild birds in Seoul, the most-developed city in South Korea. We analyzed the complete genome sequence of this isolate and estimated its origin using a phylogenetic analysis. The Seoul H5N8 isolate clustered phylogenetically with strains isolated from migratory wild birds but was distinct from Korean poultry isolates...
March 21, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28323523/rapid-dna-vaccination-against-burkholderia-pseudomallei-flagellin-by-tattoo-or-intranasal-application
#2
Jacqueline M Lankelma, Alex Wagemakers, Emma Birnie, Bastiaan W Haak, Jos J A Trentelman, Tassili A F Weehuizen, Jasmin Ersöz, Joris J T H Roelofs, Joppe W Hovius, W Joost Wiersinga, Adriaan D Bins
Melioidosis is a severe infectious disease with a high mortality that is endemic in South-East Asia and Northern Australia. The causative pathogen, Burkholderia pseudomallei, is listed as potential bioterror weapon due to its high virulence and potential for easy dissemination. Currently, there is no licensed vaccine for prevention of melioidosis. Here, we explore the use of rapid plasmid DNA vaccination against B. pseudomallei flagellin for protection against respiratory challenge. We tested three flagellin DNA vaccines with different subcellular targeting designs...
March 21, 2017: Virulence
https://www.readbyqxmd.com/read/28316351/air-contamination-by-mercury-emissions-and-transformations-a-review
#3
Barbara Gworek, Wojciech Dmuchowski, Aneta H Baczewska, Paulina Brągoszewska, Olga Bemowska-Kałabun, Justyna Wrzosek-Jakubowska
The present and future air contamination by mercury is and will continue to be a serious risk for human health. This publication presents a review of the literature dealing with the issues related to air contamination by mercury and its transformations as well as its natural and anthropogenic emissions. The assessment of mercury emissions into the air poses serious methodological problems. It is particularly difficult to distinguish between natural and anthropogenic emissions and re-emissions from lands and oceans, including past emissions...
2017: Water, Air, and Soil Pollution
https://www.readbyqxmd.com/read/28314745/differences-in-predictors-of-permanent-work-disability-between-immigrants-and-natives-a-cohort-study-of-adults-with-sick-leave-due-to-common-mental-disorders
#4
Laura Werlen, Magnus Helgesson, Ellenor Mittendorfer-Rutz
OBJECTIVES: Immigrants with common mental disorders (CMDs) are reported to have a higher risk of disability pension (DP) compared with native residents; however, the reasons for this are not fully understood. This study aimed to investigate (1) differences in morbidity (3 measures) and socioeconomic status in native Swedes, 'Western' and 'non-Western' immigrants with CMDs and (2) interactions between morbidity and socioeconomic status and immigrant status regarding subsequent DP. DESIGN: The study was a prospective population-based cohort study using national register data...
March 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28303732/mitochondrial-dna-sequence-variation-in-iranian-native-dogs
#5
Zeinab Amiri Ghanatsaman, Adeniyi C Adeola, Masood Asadi Fozi, Ya-Ping Ma, Min-Sheng Peng, Guo-Dong Wang, Ali Esmailizadeh, Ya-Ping Zhang
The dog mtDNA diversity picture from wide geographical sampling but from a small number of individuals per region or breed, displayed little geographical correlation and high degree of haplotype sharing between very distant breeds. For a clear picture, we extensively surveyed Iranian native dogs (n = 305) in comparison with published European (n = 443) and Southwest Asian (n = 195) dogs. Twelve haplotypes related to haplogroups A, B and C were shared by Iranian, European, Southwest Asian and East Asian dogs...
March 17, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28303199/hiv-aids-in-the-south-east-asia-region-progress-and-challenges
#6
EDITORIAL
Razia Pendse, Somya Gupta, Dongbao Yu, Swarup Sarkar
The South-East Asia region, with 11 member states, has an estimated 3.5 million people living with HIV (PLHIV). More than 99% of PLHIV live in five countries where HIV prevalence among the population aged 15-49 remains low but is between 2% and 29% among key populations. Since 2010, the region has made progress to combat the epidemic. Mature condom programmes exist in most countries but opioid substitution therapy, and needle and syringe exchange programmes need to be scaled up. HIV testing is recommended nationwide in four countries and is prioritised in high prevalence areas or for key populations in the rest...
November 28, 2016: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28302017/targeting-pyrimidine-pathway-of-plasmodium-knowlesi-new-strategies-towards-identification-of-novel-antimalarial-chemotherapeutic-agents
#7
Mayank Rashmi, Manoj Kumar Yadav, D Swati
Plasmodium knowlesi has been recently recognized as a human malarial parasite, particularly in the region of south-east Asia. The effective prevention and treatment of this disease is increasingly bound to fail due to the emergence of drug resistance. Hence, design of new drugs against known targets is gaining importance. Pyrimidine pathway is a crucial metabolic pathway in P. knowlesi, and the enzymes involved are also unique in terms of their structure and function as compared to its human counterpart. Thus targeting Dihydroorotase, an enzyme involved in the pyrimidine pathway, provides a promising route for novel drug development...
March 15, 2017: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/28301424/joint-estimation-of-cd4-progression-and-survival-in-untreated-individuals-with-hiv-1-infection-a-pooled-analysis-of-data-from-25-countries
#8
T D Mangal
OBJECTIVE: We compiled the largest dataset of seroconverter cohorts to date from 25 countries across Africa, North America, Europe, and SE/E. Asia to simultaneously estimate transition rates between CD4 stages and death, in ART-naive HIV-1 infected individuals. DESIGN: A hidden Markov model incorporating a misclassification matrix was used to represent natural short-term fluctuations and measurement errors in CD4 counts. Covariates were included to estimate the transition rates and survival probabilities for each subgroup...
March 15, 2017: AIDS
https://www.readbyqxmd.com/read/28300135/a-combination-mode-of-climate-variability-responsible-for-extremely-poor-recruitment-of-the-japanese-eel-anguilla-japonica
#9
Yong-Fu Lin, Chau-Ron Wu, Yu-San Han
Satellite data and assimilation products are used to investigate fluctuations in the catch of Japanese eel (Anguilla japonica) in eastern Asian countries. It has been reported that the salinity front has extended farther south, which has shifted the eel's spawning grounds to a lower latitude, resulting in smaller eel catches in 1983, 1992, and 1998. This study demonstrates that interannual variability in the eel catch is strongly correlated with the combination mode (C-mode), but not with the El Niño-Southern Oscillation...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28298208/looking-back-to-move-forward-a-twenty-year-audit-of-herpes-zoster-in-asia-pacific
#10
REVIEW
Liang-Kung Chen, Hidenori Arai, Liang-Yu Chen, Ming-Yueh Chou, Samsuridjal Djauzi, Birong Dong, Taro Kojima, Ki Tae Kwon, Hoe Nam Leong, Edward M F Leung, Chih-Kuang Liang, Xiaohong Liu, Dilip Mathai, Jiun Yit Pan, Li-Ning Peng, Eduardo Rommel S Poblete, Philip J H Poi, Stewart Reid, Terapong Tantawichien, Chang Won Won
BACKGROUND: Herpes zoster (HZ) is a prevalent viral disease that inflicts substantial morbidity and associated healthcare and socioeconomic burdens. Current treatments are not fully effective, especially among the most vulnerable patients. Although widely recommended, vaccination against HZ is not routine; barriers in Asia-Pacific include long-standing neglect of adult immunisation and sparse local data. To address knowledge gaps, raise awareness, and disseminate best practice, we reviewed recent data and guidelines on HZ from the Asia-Pacific region...
March 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28296798/all-cause-mortality-in-hiv-positive-adults-starting-combination-antiretroviral-therapy-correcting-for-loss-to-follow-up
#11
Nanina Anderegg, Leigh F Johnson, Elizabeth Zaniewski, Keri N Althoff, Eric Balestre, Matthew Law, Denis Nash, Bryan E Shepherd, Constantin T Yiannoutsos, Matthias Egger
OBJECTIVE: To estimate mortality in HIV-positive patients starting combination antiretroviral therapy (ART) and to discuss different approaches to calculating correction factors to account for loss to follow-up. METHODS: A total of 222 096 adult HIV-positive patients who started ART 2009-2014 in clinics participating in the International epidemiology Databases to Evaluate AIDS collaboration in 43 countries in sub-Saharan Africa, Asia Pacific, Latin America, and North America were included...
April 2017: AIDS
https://www.readbyqxmd.com/read/28294089/media-audit-reveals-inappropriate-promotion-of-products-under-the-scope-of-the-international-code-of-marketing-of-breast-milk-substitutes-in-south-east-asia
#12
Kristine Hansen Vinje, Linh Thi Hong Phan, Tuan Thanh Nguyen, Sigrun Henjum, Lovise Omoijuanfo Ribe, Roger Mathisen
OBJECTIVE: To review regulations and to perform a media audit of promotion of products under the scope of the International Code of Marketing of Breast-milk Substitutes ('the Code') in South-East Asia. DESIGN: We reviewed national regulations relating to the Code and 800 clips of editorial content, 387 advertisements and 217 Facebook posts from January 2015 to January 2016. We explored the ecological association between regulations and market size, and between the number of advertisements and market size and growth of milk formula...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28293218/genetic-characterization-of-continually-evolving-highly-pathogenic-h5n6-influenza-viruses-in-china-2012-2016
#13
Meng Li, Na Zhao, Jing Luo, Yuan Li, Lin Chen, Jiajun Ma, Lin Zhao, Guohui Yuan, Chengmin Wang, Yutian Wang, Yanhua Liu, Hongxuan He
H5N6 is a highly pathogenic avian influenza (HPAI) and a zoonotic disease that causes recurring endemics in East Asia. At least 155 H5N6 outbreaks, including 15 human infections, have been reported in China. These repeated outbreaks have increased concern that the H5N6 virus may cross over to humans and cause a pandemic. In February, 2016, peafowls in a breeding farm exhibited a highly contagious disease. Post-mortem examinations, including RT-PCR, and virus isolation, confirmed that the highly pathogenic H5N6 influenza virus was the causative agent, and the strain was named A/Pavo Cristatus/Jiangxi/JA1/2016...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28288924/global-expansion-of-chikungunya-virus-mapping-the-64-year-history
#14
REVIEW
Braira Wahid, Amjad Ali, Shazia Rafique, Muhammad Idrees
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that is emerging as a global threat because of its highly debilitating nature and unprecedented magnitude. The disease originated from Africa and then hit the entire globe causing large number of epidemics that infected millions of people in Asia, Indian subcontinent, Europe, Americas, and Pacific Islands. According to phylogenetic analysis, four different genotypes of CHIKV are: Asian, West African, East/Central/South African (ECSA), and Indian Ocean lineage (IOL)...
March 10, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28288060/the-global-incidence-of-appendicitis-a-systematic-review-of-population-based-studies
#15
Mollie Ferris, Samuel Quan, Belle S Kaplan, Natalie Molodecky, Chad G Ball, Greg W Chernoff, Nij Bhala, Subrata Ghosh, Elijah Dixon, Siew Ng, Gilaad G Kaplan
OBJECTIVE: We compared the incidence of appendicitis or appendectomy across the world and evaluated temporal trends. SUMMARY BACKGROUND DATA: Population-based studies reported the incidence of appendicitis. METHODS: We searched MEDLINE and EMBASE databases for population-based studies reporting the incidence of appendicitis or appendectomy. Time trends were explored using Poisson regression and reported as annual percent change (APC) with 95% confidence intervals (CI)...
March 10, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28286724/a-questionnaire-based-survey-of-physical-medicine-and-rehabilitation-residency-training-in-pakistan
#16
Farooq A Rathore, Aamir W Butt, Nabila Soomro, Noreen Akhtar
Pakistan is one of the three countries in South East Asia that has an active postgraduate physical medicine and rehabilitation (PM&R) training program. College of Physicians and Surgeons Pakistan (CPSP) offers a four-year structured training program in PM&R. It consists of clinical teaching, lectures, rotations in other specialties, and writing a research dissertation. The aim of this survey was to provide an objective analysis of the current PM&R training program, including the facilities available for training, the participation of residents in academic activities, and their participation in different PM&R procedures...
January 31, 2017: Curēus
https://www.readbyqxmd.com/read/28285312/world-perspective-on-the-epidemiology-of-stunting-between-1990-and-2015%C3%A2
#17
Susan C Campisi, Arlin Mary Cherian, Zulfiqar A Bhutta
BACKGROUND: Stunting is the most prevalent form of child undernutrition with current worldwide estimates at 156 million. The majority of these children reside in low- and middle-income countries. When stunting prevails to adulthood, optimal growth potential and economic productivity are minimized. RESULTS: In 2015 there were 98.5 million fewer stunted children under 5 years of age than in 1990. In East Asia and Pacific and South Asia, the stunting prevalence decreased by 24...
March 10, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28284653/framework-for-estimating-toxic-releases-from-the-application-of-manure-on-agricultural-soil-national-release-inventories-for-heavy-metals-in-2000-2014
#18
Alexandra Leclerc, Alexis Laurent
Livestock manure is commonly applied on agricultural land for its fertilising properties. However, the presence of toxic substances in animal manure such as pathogens, antibiotics and heavy metals, can result in damages to ecosystems and human health. To date, although relevant for policy-making, e.g. regulation framing, their releases to agricultural land have been incompletely and inconsistently quantified at global and national scales. Here, we thus developed a generic framework for estimating such releases based on the quantities of manure applied and concentrations of toxic substances...
March 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28279022/new-sedimentary-evidence-reveals-a-unique-history-of-c4-biomass-in-continental-east-asia-since-the-early-miocene
#19
Bin Zhou, Michael Bird, Hongbo Zheng, Enlou Zhang, Christopher M Wurster, Luhua Xie, David Taylor
Pyrogenic carbon (PyC) and n-alkane data from sediments in the northern South China Sea reveal variations in material from C4 plants in East Asia over the last ~19 Ma. These data indicate the likely presence of C4 taxa during the earliest part of the record analysed, with C4 species also prominent during the mid and late Miocene and especially the mid Quaternary. Notably the two records diverge after the mid Quaternary, when PyC data indicate a reduced contribution of C4 taxa to biomass burning, whereas plant-derived n-alkanes indicate a greater abundance of C4 plants...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28265721/association-between-type-2-diabetes-and-risk-of-cancer-mortality-a-pooled-analysis-of-over-771-000-individuals-in-the-asia-cohort-consortium
#20
Yu Chen, Fen Wu, Eiko Saito, Yingsong Lin, Minkyo Song, Hung N Luu, Prakash C Gupta, Norie Sawada, Akiko Tamakoshi, Xiao-Ou Shu, Woon-Puay Koh, Yong-Bing Xiang, Yasutake Tomata, Kemmyo Sugiyama, Sue K Park, Keitaro Matsuo, Chisato Nagata, Yumi Sugawara, You-Lin Qiao, San-Lin You, Renwei Wang, Myung-Hee Shin, Wen-Harn Pan, Mangesh S Pednekar, Shoichiro Tsugane, Hui Cai, Jian-Min Yuan, Yu-Tang Gao, Ichiro Tsuji, Seiki Kanemura, Hidemi Ito, Keiko Wada, Yoon-Ok Ahn, Keun-Young Yoo, Habibul Ahsan, Kee Seng Chia, Paolo Boffetta, Wei Zheng, Manami Inoue, Daehee Kang, John D Potter
AIMS/HYPOTHESIS: The aims of the study were to evaluate the association between type 2 diabetes and the risk of death from any cancer and specific cancers in East and South Asians. METHODS: Pooled analyses were conducted of 19 prospective population-based cohorts included in the Asia Cohort Consortium, comprising data from 658,611 East Asians and 112,686 South Asians. HRs were used to compare individuals with diabetes at baseline with those without diabetes for the risk of death from any cancer and from site-specific cancers, including cancers of the oesophagus, stomach, colorectum, colon, rectum, liver, bile duct, pancreas, lung, breast, endometrium, cervix, ovary, prostate, bladder, kidney and thyroid, as well as lymphoma and leukaemia...
March 7, 2017: Diabetologia
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