keyword
MENU ▼
Read by QxMD icon Read
search

Bilirubin nephropathy

keyword
https://www.readbyqxmd.com/read/28398539/bile-cast-nephropathy-in-cirrhotic-patients-effects-of-chronic-hyperbilirubinemia
#1
Michelle Foshat, Heather M Ruff, Wayne G Fischer, Robert E Beach, Mark R Fowler, Hyunsu Ju, Judith F Aronson, Marjan Afrouzian
Objectives: The aim of this study was to determine the prevalence of bile cast nephropathy (BCN) in autopsied cirrhotic patients and to correlate BCN with clinical and laboratory data to direct attention to this underrecognized renal complication of liver failure. Methods: We assessed 114 autopsy cases of cirrhosis for the presence of renal intratubular bile casts using Hall stain for bile. Presence of bile casts was correlated with etiology of cirrhosis, clinical and laboratory data, and histologic findings...
April 7, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28363276/relationship-between-serum-bilirubin-concentrations-and-diabetic-nephropathy-in-shanghai-han-s-patients-with-type-1-diabetes-mellitus
#2
Xu Li, Lei Zhang, Haibing Chen, Kaifeng Guo, Haoyong Yu, Jian Zhou, Ming Li, Qing Li, Lianxi Li, Jun Yin, Fang Liu, Yuqian Bao, Junfeng Han, Weiping Jia
BACKGROUND: Recent studies highlight a negative association between total bilirubin concentrations and albuminuria in patients with type 2 diabetes mellitus. Our study evaluated the relationship between bilirubin concentrations and the prevalence of diabetic nephropathy (DN) in Chinese patients with type 1 diabetes mellitus (T1DM). METHODS: A total of 258 patients with T1DM were recruited and bilirubin concentrations were compared between patients with or without diabetic nephropathy...
March 31, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28134328/effect-of-bilirubin-concentration-on-the-risk-of-diabetic-complications-a-meta-analysis-of-epidemiologic-studies
#3
Bo Zhu, Xiaomei Wu, Yifei Bi, Yang Yang
Diabetes can affect many parts of the body and is associated with serious complications. Oxidative stress is a major contributor in the pathogenesis of diabetic complications and bilirubin has been shown to have antioxidant effects. The number of studies on the effect of bilirubin on the risk of diabetic complications has increased, but the results are inconsistent. Thus, we performed a meta-analysis to determine the relationship between bilirubin concentration and the risk of diabetic complications, and to investigate if there was a dose-response relationship...
January 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28111217/renoprotective-and-antioxidative-effects-of-methanolic-paederia-foetida-leaf-extract-on-experimental-diabetic-nephropathy-in-rats
#4
M P Borgohain, L Chowdhury, S Ahmed, N Bolshette, K Devasani, T J Das, A Mohapatra, M Lahkar
ETHNOPHARMACOLOGICAL RELEVANCE: Paederia foetida Linn. (Family: Rubiaceae) is widely used as natural remedy for diabetes mellitus by the Nepali and Lepcha tribes of Sikkim and Darjeeling Himalayan region. The plant is administered to a diabetic individual in the form of leaf infusion for 2-3 weeks. Therefore, we investigated the effects of methanolic leaf extract of Paederia foetida (MEPF) on alloxan (ALX) induced diabetic renal oxidative stress and NF-kB dependent renoinflammatory events in rat...
January 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28093842/gilbert-syndrome-in-patients-with-type-1-diabetes-prevalence-glycemic-control-and-microalbuminuria
#5
Sigal Singer, Nurit Pilpel, Orit Pinhas-Hamiel
BACKGROUND: Gilbert syndrome (GS) is a common hereditary condition, characterized by intermittent unconjugated hyperbilirubinemia. In adults with type 2 diabetes and GS, a markedly lower prevalence of nephropathy was documented, suggesting a beneficial effect of hyperbilirubinemia. We investigated the prevalence of GS among individuals with type 1 diabetes mellitus (T1DM), and the prevalence of microalbuminuria. METHODS: The prevalence of GS was assessed in 401 (204 female) patients with T1DM, median age 21...
January 17, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28072721/total-bilirubin-level-may-be-a-biomarker-of-nephropathy-in-type-2-diabetes-mellitus-a-meta-analysis-of-observational-studies-based-on-moose-compliant
#6
Dan Zhang, Bo Zhu, Wei Zhang, Wei Wang, Dan Guo, Ligang Yang, Lu Wang
Recently, the number of the studies on the relationship between the total bilirubin level (TBL) and diabetic nephropathy (DN) is increasing, but their results were not consistent. Therefore, we performed a meta-analysis to analyze the relationship between TBL and the risk of DN.We searched 5 databases before October 31, 2016, and reviewed the reference list of relevant articles. The fixed or random-effects model was used to pool risk estimates. We conducted the dose-response meta-analysis to evaluate the relationship between TBL and the risk of DN...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27994859/primary-sclerosing-cholangitis-a-new-cause-of-distal-renal-tubular-acidosis
#7
Valentin Goutaudier, Ilan Szwarc, Jean-Emmanuel Serre, Georges-Philippe Pageaux, Àngel Argilés, Jean Ribstein
We describe the first case of distal renal tubular acidosis (dRTA) associated with primary sclerosing cholangitis. A 26-year-old Lao-Thai male patient presented with severe jaundice, metabolic acidosis and hypokalaemia. He was diagnosed of dRTA. Liver transplantation resulted in correction of electrolyte disturbances and hyperbilirubinaemia. A fludrocortisone-furosemide test revealed normal urinary acidification, demonstrating no residual dRTA. This observation suggests that dRTA may be an early manifestation of bilirubin-associated nephropathy or the consequence of an immune mechanism...
December 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27981738/comparison-of-exposure-response-relationship-of-atrasentan-between-north-american-and-asian-populations
#8
Hiddo J L Heerspink, Hirofumi Makino, Dennis Andress, John J Brennan, Ricardo Correa-Rotter, Blai Coll, Justin W Davis, Ken Idler, Donald E Kohan, Mohan Liu, Vlado Perkovic, Giuseppe Remuzzi, Sheldon W Tobe, Robert Toto, Hans-Henrik Parving, Dick de Zeeuw
AIMS: The selective endothelin (ET) A receptor antagonist atrasentan has been shown to lower albuminuria in North American and Asian patients with type 2 diabetes and nephropathy. As drug responses to many drugs may differ between North American and Asian populations, we assessed the influence of geographical region on the albuminuria and fluid retention response to atrasentan. MATERIALS AND METHODS: Two 12-week double-blind randomised controlled trials were performed with atrasentan 0...
December 15, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27891331/association-of-diabetic-nephropathy-and-liver-disorders
#9
Usha Sachidananda Adiga, B N Malawadi
INTRODUCTION: Liver disorder is known to be a risk factor for Diabetes Mellitus (DM) and diabetic patients are at risk of developing liver disorders. Association of liver and renal disease is less explored in the field of research; hence, we conducted a retrospective study on this. AIM: To compare the renal and liver profiles of type II DM patients compared to healthy controls and find the association between the two profiles in diabetics. MATERIALS AND METHODS: The renal and liver profiles of 68 type II DM patients and 58 controls were compared...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27852844/bilirubin-levels-are-associated-with-contrast-induced-nephropathy-in-peripheral-artery-disease
#10
Ertan Vuruşkan, Erhan Saraçoğlu
The relationship between contrast-induced nephropathy (CIN) and oxidative mechanisms is well documented. Our aim was to demonstrate the possible relationship between CIN and serum bilirubin as an antioxidant molecule. This retrospective study included 359 patients with peripheral artery disease (PAD) who underwent peripheral diagnostic angiography; 179 developed CIN after the intervention and another 180 were the control group, matched for age, gender, and cardiovascular risk factors. Baseline, 48- to 72-hour, and 30-day laboratory values, major adverse cardiovascular events, and dialysis requirements were recorded...
November 15, 2016: Angiology
https://www.readbyqxmd.com/read/27847209/in-vivo-study-for-anti-hyperglycemic-potential-of-aqueous-extract-of-basil-seeds-ocimum-basilicum-linn-and-its-influence-on-biochemical-parameters-serum-electrolytes-and-haematological-indices
#11
Sachin Chaudhary, Amit Semwal, Hitesh Kumar, Harish Chandra Verma, Amit Kumar
The study introduced anti-hyperglycemic influence of aqueous extract of Ocimum basilicum seeds (AEOBS) in Streptozotocin (STZ) induced diabetic rats and estimating its potential to ameliorate altered level of biochemical parameters, serum electrolytes level and haematological indices along with its effect on body weight of treated rats. The albino rats were selected to observe oral glucose tolerance test by oral intake of aq. glucose solution (4g/kg, body weight) in normal rats and estimation of blood glucose level after administration of AEOBS at 250mg/kg, 500mg/kg and standard drug glibenclamide at 0...
December 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27780576/bile-cast-nephropathy-caused-by-obstructive-cholestasis
#12
Julien Aniort, Anaïs Poyet, Jean-Louis Kemeny, Carole Philipponnet, Anne-Elisabeth Heng
Acute kidney injury (AKI) is a major complication in patients with liver disease. Although hepatorenal syndrome is frequently involved, bile cast nephropathy, characterized by tubular bile cast formation, has been scarcely described in the setting of severe liver failure. Few renal histology studies are available in these patients. We describe a case of bile cast nephropathy in a patient with obstructive cholestasis caused by stones in the common bile duct. The kidney biopsy confirmed this diagnosis, with several green casts in tubular lumens, tubular injury, and bilirubin composition of the tubular casts with Hall stain...
January 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27478612/urinary-bile-casts-in-bile-cast-nephropathy-secondary-to-severe-falciparum-malaria
#13
Manoj Kumar Mohapatra, Ashok Kumar Behera, Purna Chandra Karua, Prafulla Kumar Bariha, Ashutosh Rath, Kailash Chandra Aggrawal, Snigdha Rani Nahak, Santosh Shankar Gudaganatti
BACKGROUND: Severe cholestatic jaundice may complicate with bile cast nephropathy (BCN) causing severe acute kidney injury (AKI). In this study, we investigate BCN in severe falciparum malaria complicated with jaundice and AKI. METHODS: This prospective study was conducted in a tertiary health care institution with high prevalence of malaria. A cohort of 110 patients with falciparum malaria complicated with cerebral malaria, jaundice and AKI were enrolled. Species diagnosis was made from peripheral blood smear or rapid diagnostic test...
August 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27468221/bile-cast-nephropathy-a-case-report-and-review-of-the-literature
#14
REVIEW
Jaymon Patel, Saqib Walayat, Nikhil Kalva, Sidney Palmer-Hill, Sonu Dhillon
Bile cast nephropathy is a condition of renal dysfunction in the setting of hyperbilirubinemia. There are very few cases of this condition reported in the last decade and a lack of established treatment guidelines. While the exact etiology remains unknown, bile cast nephropathy is presumed to be secondary to multiple concurrent insults to the kidney including direct toxicity from bile acids, obstructive physiology from bile casts, and systemic hypoperfusion from vasodilation. Therapy directed at bilirubin reduction may improve renal function, but will likely need dialysis or plasmapheresis as well...
July 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27389722/efficacy-of-extracorporeal-albumin-dialysis-for-acute-kidney-injury-due-to-cholestatic-jaundice-nephrotoxicity
#15
Florence Sens, Justine Bacchetta, Maud Rabeyrin, Laurent Juillard
We report a case of a 37-year-old man with Maturity Onset Diabetes of the Youth (MODY) type 5, admitted for an episode of cholestasis and a simultaneous acute kidney injury (AKI). Chronic liver disease was due to a mutation in the transcription factor 2 (TCF2) gene, thus highlighting the need for a close liver follow-up in these patients. AKI was attributed to a cholemic nephropathy based on the following rationale: (1) alternative diagnoses were actively ruled out; (2) the onset of AKI coincided with the onset of severe hyperbilirubinaemia; (3) renal pathology showed large bile tubular casts and a marked tubular necrosis and (4) creatinine serum dramatically decreased when bilirubin levels improved after the first sessions of extracorporeal albumin dialysis (ECAD), thus suggesting its role in renal recovery...
July 7, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27381964/the-role-of-vitamin-d-obesity-and-physical-exercise-in-regulation-of-glycemia-in-type-2-diabetes-mellitus-patients
#16
Abdulbari Bener, Abdulla O A A Al-Hamaq, Eda Merve Kurtulus, Waleed K Abdullatef, Mahmoud Zirie
AIM: The aims of this study were to determine the role of vitamin D, obesity and physical exercise in the regulation of glycemia in Type 2 Diabetes Mellitus patients in a highly consanguineous population. DESIGN: Case and control study. SETTING: The survey was carried out at the Hamad General Hospital and Primary Health Care (PHC) centers in the State of Qatar. SUBJECTS: The study was conducted from November 2012 to June 2014 among subjects above 30 years of age...
October 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/26819426/-relationship-between-serum-cystatin-c-levels-and-vibrating-perception-threshold-in-patients-with-%C3%A2-type-2-diabetes-mellitus
#17
Pijun Yan, Zhihong Zhang, Yong Xu, Qin Wan, Hongyan Ma, Jianhua He
OBJECTIVE: To explore the relationship between serum cystatin-C (Cys-c) levels and vibrating perception threshold (VPT) in patients with Type 2 diabetes mellitus (T2DM).
 METHODS: According to the symptoms, signs and results of lab examination, a total of 352 patients with T2DM were divided into a diabetic peripheral neuropathy group (DPN group, n=107) and a non-diabetic peripheral neuropathy group (NDPN group, n=245). Serum Cys-c levels were measured by radioimmunoassay method...
January 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/26697217/hyperglycaemic-environment-contribution-to-the-anaemia-associated-with-diabetes-mellitus-in-rats-experimentally-induced-with-alloxan
#18
Oseni Bashiru Shola, Fakoya Olatunde Olugbenga
UNLABELLED: Background. Diabetes mellitus characterized by hyperglycaemia presents with various complications amongst which anaemia is common particularly in those with overt nephropathy or renal impairment. The present study has examined the contribution of the hyperglycaemic environment in diabetic rats to the anaemia associated with diabetes mellitus. METHOD: Sixty male albino rats weighing 175-250 g were selected for this study and divided equally into control and test groups...
2015: Anemia
https://www.readbyqxmd.com/read/26315331/diabetic-hepatosclerosis-another-diabetes-microvascular-complication
#19
R J King, L Harrison, S G Gilbey, A Santhakumar, J Wyatt, R Jones, H J Bodansky
BACKGROUND: Liver disease in diabetes is common and is frequently the result of hepatic steatosis. Diabetic hepatosclerosis is a relatively recent description of sinusoidal fibrosis, without steatosis, observed in liver biopsies of people with diabetes presenting with cholestasis. Its association with other microvascular complications suggests it is a form of hepatic diabetic microangiopathy. CASE REPORT: We report the case of a 50-year-old woman with longstanding Type 1 diabetes, complicated by nephropathy resulting in cadaveric renal transplant, retinopathy, gastroparesis and neuropathy with slowly healing ulceration to her right foot...
February 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/26238275/novel-marker-for-the-detection-of-sickle-cell-nephropathy-soluble-fms-like-tyrosine-kinase-1-sflt-1
#20
Ilham Youssry, Samuel Makar, Rania Fawzy, Manal Wilson, Ghada AbdAllah, Eman Fathy, Happy Sawires
BACKGROUND: Given the burden and poor outcome of end-stage renal disease in sickle cell disease (SCD), early markers of sickle cell nephropathy (SN) are desirable. Disordered angiogenesis underlies many complications of SCD. We aimed to determine the relationship between serum FMS-like tyrosine kinase-1 (sFLT-1) and other biomarkers of renal damage for the early diagnosis of SN. METHODS: Forty-seven SCD patients and 49 healthy controls were enrolled. Microalbuminuria was determined in patient urine samples...
December 2015: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
keyword
keyword
97621
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"