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JOURNAL ARTICLE
Daniele Balducci, Clément Archimbaud, Jean-Philippe Ratone, Yanis Dahel, Solene Hoibian, Fabrice Caillol, Marc Giovannini
No abstract text is available yet for this article.
December 2024: Endoscopy
#2
JOURNAL ARTICLE
Fabrice Caillol, Sébastien Godat, Alexey Solovyev, Amina Harouchi, Sarra Oumrani, Mariola Marx, Solene Hoibian, Yanis Dahel, Jean-Philippe Ratone, Marc Giovannini
Background and study aims In cases of inaccessible papilla, EUS-guided biliary drainage (EUS-BD) has been described as an alternative to calibrate benign biliary stenosis. However, few studies are available. Patients and methods This tw-center, retrospective study was designed to evaluate technical success and clinical success at 1 year. All patients who underswent EUS-BD without the rendezvous technique used for calibration of benign biliary stenosis were included from 2016 to 2022. Patients underwent EUS-hepaticogastrostomy (EUS-HGS) during the first session...
March 2024: Endoscopy International Open
#3
JOURNAL ARTICLE
Olivier Walger, Anne Bramaud Du Boucheron, Véronique Haberey-Knuessi, Marco Pedrotti, Marc Giovannini
Intermed, a primary care support nurse (PCN) model, was piloted from 2014 to 2021 in a general practice in La Chaux-de-Fonds. In collaboration with the physician and medical assistant, the PCN supports a proactive Chronic Care Model organization, and focuses specifically on patients in complex chronic situations. Integrated into the medical center, the PCN benefits from a close relationship with the physician. Her services, without apparent additional cost, often clarify the functioning of the network around the patients while allowing the latter to regain control over their care...
January 24, 2024: Revue Médicale Suisse
#4
JOURNAL ARTICLE
Mariola Marx, Fabrice Caillol, Sébastien Godat, Flora Poizat, Sarra Oumrani, Jean-Philippe Ratone, Solène Hoibian, Yanis Dahel, Sandrine Oziel-Taieb, Patricia Niccoli, Jacques Ewald, Emmanuel Mitry, Marc Giovannini
BACKGROUND: Current guidelines consider observation a reasonable strategy for G1 or G2 nonfunctional pancreatic neuroendocrine tumors (nf pNETs) ≤2 cm. We aimed to characterize their natural behavior and confront the data with the outcomes of patients undergoing upfront surgery. METHODS: Data from patients with histologically confirmed nf pNETs ≤2 cm, managed at a single tertiary referral center between 2002 and 2020, were retrospectively reviewed...
2023: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
#5
JOURNAL ARTICLE
Kien Vu Trung, Christian Heise, Einas Abou-Ali, Francesco Auriemma, Elias Karam, Sophia E van der Wiel, Marco J Bruno, Fabrice Caillol, Marc Giovannini, Viliam Masaryk, Uwe Will, Andrea Anderloni, Enrique Pérez-Cuadrado-Robles, Ana Dugic, Benjamin Meier, Woo H Paik, Maria C Petrone, Dörte Wichmann, Mario Dinis-Ribeiro, Tiago C Gonçalves, Edris Wedi, Arthur Schmidt, Aiste Gulla, Albrecht Hoffmeister, Jonas Rosendahl, Jean Philippe Ratone, Rita Saadeh, Alessandro Repici, Pierre Deprez, Alain Sauvanet, Francois R Souche, Jean M Fabre, Steffen Muehldorfer, Karel Caca, Matthias Löhr, Patrick Michl, Sebastian Krug, Sara Regner, Sebastien Gaujoux, Marcus Hollenbach
BACKGROUND AND AIMS: Ampullary lesions (AL) of the minor duodenal papilla are extremely rare. Endoscopic papillectomy (EP) is a routinely used treatment for AL of the major duodenal papilla but the role of EP for minor AL has not been accurately studied. METHODS: We identified 20 patients with AL of minor duodenal papilla out of the multicentric database from the ESAP study that included 1422 EPs. We used the propensity score matching (nearest-neighbor method), to match these cases with ampullary lesions of the major duodenal papilla based on age, gender, histologic subtype and size of the lesion in a 1:2-ratio...
November 9, 2023: Gastrointestinal Endoscopy
#6
JOURNAL ARTICLE
Sebastian Stefanovic, Douglas G Adler, Alexander Arlt, Todd H Baron, Kenneth F Binmoeller, Michiel Bronswijk, Marco J Bruno, Jean-Baptiste Chevaux, Stefano Francesco Crinò, Helena Degroote, Pierre H Deprez, Peter V Draganov, Pierre Eisendrath, Marc Giovannini, Manuel Perez-Miranda, Ali A Siddiqui, Rogier P Voermans, Dennis Yang, Pieter Hindryckx
OBJECTIVES: The study aimed to develop international consensus recommendations on the safe use of lumen-apposing metal stents (LAMSs) for on- and off-label indications. METHODS: Based on the available literature, statements were formulated and grouped into the following categories: general safety measures, peripancreatic fluid collections (PFC), biliary drainage (EUS-BD), gallbladder drainage (EUS-GBD), gastroenterostomy (EUS-GE) and gastric access temporary for endoscopy (GATE)...
November 7, 2023: American Journal of Gastroenterology
#7
JOURNAL ARTICLE
Jean-Philippe Ratone, Clément Archimbaud, Alexey Solovyev, Christophe Zemmour, Christian Pesenti, Solène Hoibian, Yanis Dahel, Mariola Marx, Cécile De Chaisemartin, Brice Chanez, Hélène Meillat, Bernard Lelong, Flora Poizat, Fabrice Caillol, Marc Giovannini
BACKGROUND AND AIMS: Colorectal lesions measuring greater than 20 mm are unsuitable for en bloc endoscopic mucosal resection (EMR): piecemeal EMR (PM-EMR) and endoscopic submucosal dissection (ESD) are needed. The European Society of Gastrointestinal Endoscopy (ESGE) recommends ESD only for microinfiltrative lesions, although Japanese teams perform en bloc ESD for all lesions. We report the outcomes obtained in our endoscopy unit for these lesions and assess the hybrid "knife-assisted piecemeal EMR" (KAPM-EMR) technique...
September 28, 2023: Journal of Gastrointestinal and Liver Diseases: JGLD
#8
JOURNAL ARTICLE
Anudeep Katrevula, Aniruddha Pratap Singh, Marc Giovannini, Sundeep Lakhtakia, Nageshwar Reddy Duvvur
Video 1Contrast-enhanced harmonic EUS-guided radiofrequency ablation of hepatocellular carcinoma.
September 2023: VideoGIE
#9
REVIEW
Marc Giovannini, Mariola Marx
Today, endoscopic ultrasound-guided radiofrequency ablation has become increasingly accepted for the treatment of different precancerous and neoplastic lesions of the pancreas, particularly in patients who are unfit for surgery. However, thermal ablation has long been suspected to induce pancreatitis or to injure adjacent structures. Published case reports and case series on this topic are of limited size and are often based on a heterogeneous study population, reporting on functional and nonfunctional pancreatic neuroendocrine tumors...
October 2023: Gastrointestinal Endoscopy Clinics of North America
#10
JOURNAL ARTICLE
Emmanuelle Masson, Wen-Bin Zou, Na Pu, Vinciane Rebours, Emmanuelle Génin, Hao Wu, Jin-Huan Lin, Yuan-Chen Wang, Zhao-Shen Li, David N Cooper, Claude Férec, Zhuan Liao, Jian-Min Chen
BACKGROUND: PRSS1 was the first reported chronic pancreatitis (CP) gene. The existence of both gain-of-function (GoF) and gain-of-proteotoxicity (GoP) pathological PRSS1 variants, together with the fact that PRSS1 variants have been identified in CP subtypes spanning the range from monogenic to multifactorial, has made the classification of PRSS1 variants very challenging. METHODS: All currently reported PRSS1 variants (derived primarily from two databases) were manually reviewed with respect to their clinical genetics, functional analysis and population allele frequency...
August 2023: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
#11
JOURNAL ARTICLE
Il Sang Shin, Jong Ho Moon, Yun Nah Lee, Jun Ho Myeong, Tae Hoon Lee, Jae Kook Yang, Young Deok Cho, Sang-Heum Park, Marc Giovannini
BACKGROUND AND AIMS: Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) has a risk of serious procedural adverse events (AEs), but few dedicated devices for EUS-HGS are available. We evaluated the feasibility of a new partially covered self-expandable metal stent (PCSEMS) with an anchoring flange for EUS-HGS. METHODS: The feasibility of a stent featuring a proximal radiopaque uncovered portion 1.5 cm in length and a distal anchoring flange 20 mm in diameter was evaluated in consecutive patients undergoing EUS-HGS for unresectable malignant biliary obstruction...
July 18, 2023: Gastrointestinal Endoscopy
#12
Marco J Bruno, Torsten Beyna, David Carr-Locke, Prabhleen Chahal, Guido Costamagna, Benedict Devereaux, Marc Giovannini, Mahesh K Goenka, Christopher Khor, James Lau, Gary May, V Raman Muthusamy, Sandeep Patel, Bret T Petersen, Douglas K Pleskow, Isaac Raijman, D Nageshwar Reddy, Alessandro Repici, Andrew S Ross, Divyesh V Sejpal, Stuart Sherman, Uzma D Siddiqui, Christopher Ziady, Joyce A Peetermans, Matthew J Rousseau, Adam Slivka
BACKGROUND: The first commercialized single-use duodenoscope was cleared by the US Food and Drug Administration in December 2019. Data regarding endoscopic retrograde cholangiopancreatography (ERCP) using a single-use duodenoscope are needed on a broader range of cases conducted by endoscopists with varying levels of experience in a wide range of geographic areas. METHODS: 61 endoscopists at 22 academic centers in 11 countries performed ERCP procedures in adult patients aged ≥ 18...
September 20, 2023: Endoscopy
#13
JOURNAL ARTICLE
Rafael Romero-Castro, Isabel Carmona-Soria, Victoria Alejandra Jiménez-García, Paula Fernández-Álvarez, Ángel Caunedo-Álvarez, Marc Giovannini, Atsushi Irisawa
No abstract text is available yet for this article.
December 2023: Endoscopy
#14
JOURNAL ARTICLE
Elias Karam, Marcus Hollenbach, Einas Abou Ali, Francesco Auriemma, Andrea Anderloni, Louise Barbier, Giulio Belfiori, Fabrice Caillol, Stefano Crippa, Marco Del Chiaro, Charles De Ponthaud, Yanis Dahel, Massimo Falconi, Marc Giovannini, Dominik Heling, Yosuke Inoue, William R Jarnagin, Galen Leung, Renato M Lupinacci, Alberto Mariani, Viliam Masaryk, Rainer Christoph Miksch, Nicolas Musquer, Bertrand Napoleon, Atsushi Oba, Stefano Partelli, Maria C Petrone, Frédéric Prat, Alessandro Repici, Alain Sauvanet, Katrin Salzmann, Mark A Schattner, Richard Schulick, Lilian Schwarz, Kevin Soares, François R Souche, Stéphanie Truant, Jean C Vaillant, Tiegong Wang, Edris Wedi, Jens Werner, Tobias J Weismüller, Dörte Wichmann, Uwe Will, Piera Zaccari, Aiste Gulla, Christian Heise, Sara Regner, Sébastien Gaujoux
INTRODUCTION: Ampullary neuroendocrine neoplasia (NEN) are rare and evidence regarding their management is scarce. This study aimed to describe clinico-pathological features, management and prognosis of ampullary NEN according to their endoscopic or surgical management. METHODS: From a multi-institutional international database patients treated with either endoscopic papillectomy (EP), transduodenal ampullectomy (TSA) or pancreatoduodenectomy (PD) for ampullary NEN were included...
June 27, 2023: Neuroendocrinology
#15
JOURNAL ARTICLE
Yanis Dahel, Brice Chanez, Christophe Zemmour, Gilles Piana, Emmanuel Mitry, Marc Giovannini
EUS associated with contrast-enhanced harmonic EUS (CH-EUS) and EUS elastography (EUS-E) are used in clinical practice to assess pancreatic tumor at the diagnosis. In case of pancreatic ductal adenocarcinoma (PDAC) with liver metastasis, nab-paclitaxel combined with gemcitabine is a first-line treatment option. We aimed to assess the modification of PDAC microenvironment induced by the combination of nab-paclitaxel with gemcitabine, by endoscopic ultrasonography techinics. This single center phase III study conducted between February 2015 and June 2016 included patients with pancreatic adenocarcinoma with mesurable liver metastasis and no prior cancer treatment fit for two cycles of nab-paclitaxel combined with gemcitabine...
2023: Endoscopic Ultrasound
#16
JOURNAL ARTICLE
Fanny Mochel, Domitille Gras, Marie-Pierre Luton, Manon Nizou, Donatella Giovannini, Caroline Delattre, Mélodie Aubart, Magalie Barth, Anne De Saint-Martin, Diane Doummar, Nouha Essid, Alexa Garros, Caroline Hachon Le Camus, Celia Hoebeke, Sylvie Nguyen The Tich, Maximilien Perivier, Serge Rivera, Anne Rolland, Agathe Roubertie, Catherine Sarret, Caroline Sevin, Dorothee Ville, Marc Sitbon, Jean-Marc Costa, Roser Pons, Angels GarcÃa-Cazorla, Sandrine Vuillaumier, Vincent Petit, Odile Boespflug-Tanguy, Darryl C De Vivo
ObjectiveGLUT1 deficiency syndrome (Glut1DS) is a treatable neurometabolic disease that causes a wide range of neurological symptoms in children and adults. However, its diagnosis relies on an invasive test, i.e., a lumbar puncture (LP) to measure glycorrhachia, and, sometimes complex, molecular analyses of the SLC2A1 gene. This procedure limits the number of patients able to receive the standard of care. We wished to validate the diagnostic performance of METAglut1™, a simple blood test that quantifies GLUT1 at the erythrocyte surface...
April 19, 2023: Neurology
#17
JOURNAL ARTICLE
Bertrand Napoléon, Andrea Lisotti, Fabrice Caillol, Mohamed Gasmi, Philippe Ah-Soune, Arthur Belle, Antoine Charachon, Franck Cholet, Pierre-Yves Eyraud, Philippe Grandval, Jean-Michel Gonzalez, Francois Habersetzer, Stéphane Koch, Marc Le Rhun, Luigi Mangialavori, Nicolas Musquer, Maxime Palazzo, Laurent Poincloux, Jocelyn Privat, Adrien Sportes, Morgane Stouvenot, Clement Subtil, Lucie Thomassin, Geoffroy Vanbiervliet, Guillaume Vidal, Lucine Vuitton, Marc Giovannini, Marc Barthet
BACKGROUND AND AIMS: Endoscopic ultrasound radiofrequency ablation (EUS-RFA) has been described as a potentially curative option for solid and cystic pancreatic neoplasms. We aimed to assess the safety and efficacy of pancreatic EUS-RFA in a large study population. METHODS: A retrospective study retrieving all consecutive patients who underwent pancreatic EUS-RFA during 2019-2020 in France has been conducted. Indication, procedural characteristics, early and late adverse events (AEs), and clinical outcomes have been recorded...
April 12, 2023: Gastrointestinal Endoscopy
#18
JOURNAL ARTICLE
Mariola Marx, Fabrice Caillol, Aurélie Autret, Jean-Philippe Ratone, Christophe Zemmour, Jean Marie Boher, Christian Pesenti, Erwan Bories, Marc Barthet, Bertrand Napoléon, Marc Giovannini
BACKGROUND AND OBJECTIVES: Over the last two decades, EUS-guided hepaticogastrostomy (EUS-HGS) has emerged as a therapeutic alternative for patients with biliary obstruction and failed ERCP. Percutaneous transhepatic biliary drainage (PTBD) as the gold standard is associated with relevant morbidity and need for re-intervention. The aim of our work was to evaluate in a phase II study the safety and efficacy profile of EUS-HGS. A PTBD arm was considered a control group. PATIENTS AND METHODS: We conducted a prospective, randomized, noncomparative phase II study in three French tertiary centers involving patients with benign or malignant obstructive jaundice after failure of ERCP...
2022: Endoscopic Ultrasound
#19
JOURNAL ARTICLE
Emmanuelle Masson, Maren Ewers, Sumit Paliwal, Kiyoshi Kume, Virginie Scotet, David N Cooper, Vinciane Rebours, Louis Buscail, Karen Rouault, Amandine Abrantes, Lina Aguilera Munoz, Jérémie Albouys, Laurent Alric, Xavier Amiot, Isabelle Archambeaud, Solène Audiau, Laetitia Bastide, Julien Baudon, Guy Bellaiche, Serge Bellon, Valérie Bertrand, Karine Bideau, Kareen Billiemaz, Claire Billioud, Sabine Bonnefoy, Corinne Borderon, Barbara Bournet, Estelle Breton, Mathias Brugel, Louis Buscail, Guillaume Cadiot, Marine Camus, Marine Carpentier-Pourquier, Patrick Chamouard, Ulriikka Chaput, Jian-Min Chen, Franck Cholet, Dragos Marius Ciocan, Christine Clavel, Benoit Coffin, Laura Coimet-Berger, Simona Cosconea, Isabelle Creveaux, Adrian Culetto, Oussama Daboussi, Louis De Mestier, Thibault Degand, Christelle D'engremont, Bernard Denis, Solène Dermine, Desgrippes, Augustin Drouet D'Aubigny, Raphaël Enaud, Alexandre Fabre, Claude Férec, Dany Gargot, Eve Gelsi, Elena Gentilcore, Rodica Gincul, Emmanuelle Ginglinger-Favre, Marc Giovannini, Cécile Gomercic, Hannah Gondran, Thomas Grainville, Philippe Grandval, Denis Grasset, Stéphane Grimaldi, Sylvie Grimbert, Hervé Hagege, Sophie Heissat, Olivia Hentic, Anne Herber-Mayne, Marc Hervouet, Solene Hoibian, Jérémie Jacques, Bénédicte Jais, Mehdi Kaassis, Stéphane Koch, Elodie Lacaze, Joël Lacroute, Thierry Lamireau, Lucie Laurent, Xavier Le Guillou, Marc Le Rhun, Sarah Leblanc, Philippe Levy, Astrid Lievre, Diane Lorenzo, Frédérique Maire, Kévin Marcel, Emmanuelle Masson, Jacques Mauillon, Stéphanie Morgant, Driffa Moussata, Nelly Muller, Sophie Nambot, Bertrand Napoleon, Anne Olivier, Maël Pagenault, Anne-Laure Pelletier, Olivier Pennec, Fabien Pinard, Mathieu Pioche, Bénédicte Prost, Lucille Queneherve, Vinciane Rebours, Noemi Reboux, Samia Rekik, Ghassan Riachi, Barbara Rohmer, Bertrand Roquelaure, Isabelle Rosa Hezode, Florian Rostain, Jean-Christophe Saurin, Laure Servais, Roxana Stan-Iuga, Clément Subtil, Jérémy Tanneche, Charles Texier, Lucie Thomassin, David Tougeron, Lucine Vuitton, Timothée Wallenhorst, Marc Wangerme, Hélène Zanaldi, Frank Zerbib, Seema Bhaskar, Kazuhiro Kikuta, G Venkat Rao, Shin Hamada, D Nageshwar Reddy, Atsushi Masamune, Giriraj Ratan Chandak, Heiko Witt, Claude Férec, Jian-Min Chen
BACKGROUND: PRSS1 and PRSS2 constitute the only functional copies of a tandemly-arranged five-trypsinogen-gene cluster (i.e., PRSS1, PRSS3P1, PRSS3P2, TRY7 and PRSS2) on chromosome 7q35. Variants in PRSS1 and PRSS2, including missense and copy number variants (CNVs), have been reported to predispose to or protect against chronic pancreatitis (CP). We wondered whether a common trypsinogen pseudogene deletion CNV (that removes two of the three trypsinogen pseudogenes, PRSS3P2 and TRY7) might be associated with CP causation/predisposition...
January 2023: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
#20
JOURNAL ARTICLE
Isabel Amendoeira, Paolo Giorgio Arcidiacono, Jessica Barizzi, Arrigo Capitanio, Miriam Cuatrecasas, Francesco Maria Di Matteo, Claudio Doglioni, Noriyoshi Fukushima, Franco Fulciniti, Angels Ginès, Marc Giovannini, Li Zaibo, Joanne Lopes, Giovanni Lujan, Alice Parisi, Flora Poizat, Luca Reggiani Bonetti, Serena Stigliano, Chiara Taffon, Martina Verri, Anna Crescenzi
BACKGROUND: Pancreatic cancer is an aggressive malignancy and a leading cause of cancer death worldwide; its lethality is partly linked to the difficulty of early diagnosis. Modern devices for endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) were recently developed to improve targeting and sampling of small lesions, but innovative technologies for microscopic assessment are still lacking. Ex vivo fluorescence confocal laser microscopy (FCM) is a new digital tool for real-time microscopic assessment of fresh unfixed biological specimens, avoiding conventional histological slide preparation and potentially being highly appealing for EUS-FNB specimens...
November 24, 2022: EBioMedicine
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