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Clinical pharmacy

Emanuela V Mooney, Jeffrey G Hamper, Robert T Willis, Tonna L Farinha, Charlotte A Ricchetti
OBJECTIVE: To evaluate patient satisfaction with pharmacist-administered long-acting injectable antipsychotics (LAIAs) in the community pharmacy. DESIGN: Prospective survey. SETTING: Albertsons Companies community pharmacies during December 2016 to February 2017. PARTICIPANTS: Patients receiving LAIAs at participating pharmacies. MAIN OUTCOME MEASURES: A survey assessed patients' satisfaction with pharmacist-administered LAIAs in the community pharmacy...
July 2018: Journal of the American Pharmacists Association: JAPhA
Evan S Drake, Danielle K Harris, Macary Weck Marciniak
OBJECTIVES: To demonstrate the effectiveness of a community pharmacist-led intervention to identify persons with diabetes not receiving statin therapy. SETTING: Five pharmacy locations within 1 district of a chain community pharmacy. PRACTICE DESCRIPTION: Walgreens Pharmacy is a national retail chain community pharmacy with global affiliations. Walgreens Pharmacy locations use clinical pharmacy services to provide complete quality patient care...
July 2018: Journal of the American Pharmacists Association: JAPhA
Beth Fylan, Mark Tranmer, Gerry Armitage, Alison Blenkinsopp
INTRODUCTION: The complex healthcare system that provides patients with medicines places them at risk when care is transferred between healthcare organisations, for example discharge from hospital. Consequently, understanding and improving medicines management, particularly at care transfers, is a priority. OBJECTIVES: This study aimed to explore the medicines management system as patients experience it and determine differences in the patient-perceived importance of people in the system...
June 30, 2018: Research in Social & Administrative Pharmacy: RSAP
Edward Wang, Ravish Jootun, Amanda Foster
BACKGROUND: The acute surgical unit (ASU) model of acute general surgery care offers efficient patient assessment, improved clinical outcomes and has been demonstrated to be cost-efficient. Despite this, the management of acute appendicitis in our ASU was found to be highly cost-negative. This study sought to identify the drivers of increased cost. METHODS: A retrospective cost analysis of all patients with uncomplicated acute appendicitis in 2016 was undertaken to investigate the drivers of increased cost...
July 11, 2018: ANZ Journal of Surgery
Z N Cochrane, D J Berger, A K Viall, D Schrunk, J F Hans Coetzee
OBJECTIVES: To determine the potency and reproducibility of milbemycin oxime when compounded as an aqueous suspension (20 mg/mL). MATERIALS AND METHODS: Preparation choice reflected current prescribing practices. Samples were acquired by prescription from two national veterinary compounding pharmacies at three time points. Two different storage conditions were evaluated and sampled at four time points from the order date (day 7, 14, 21 and 28). Milbemycin oxime recovery was performed by solid-phase extraction and concentration strength measured via high-performance liquid chromatography...
July 11, 2018: Journal of Small Animal Practice
Amir Yosef, Emily Z Touloukian, Vinod E Nambudiri
Bruton tyrosine kinase plays a critical role in hastening cell proliferation. Bruton tyrosine kinase inhibitors are a class of immunotheraputic agents that disrupt this signaling pathway. Ibrutinib, a novel Bruton tyrosine kinase inhibitor approved by the Food and Drug Administration (FDA) for the treatment of Waldenstrom macroglobulinemia in patients who have failed treatment with other agents, has emerged as an important therapeutic agent in the management of Waldenstrom macroglobulinemia and other plasma cell dyscrasias...
January 1, 2018: Journal of Oncology Pharmacy Practice
Timothy T Pham, Grant H Skrepnek, Christopher Bond, Thomas Alfieri, Terry J Cothran, Shellie L Keast
BACKGROUND: Medicaid members are predisposed to unintentional prescription opioid overdose. However, little is known about their individual risk factors. OBJECTIVES: To describe demographic and clinical characteristics, medical utilization, opioid use, concurrent use of benzodiazepines, risk factors, and substances involved in death for Oklahoma's Medicaid members who died of unintentional prescription opioid poisoning. SUBJECTS: Decedents who were Medicaid eligible in Oklahoma during the year of death, had an opioid recorded in cause of death, and had ≥1 opioid prescription claim between January 1, 2011 and June 30, 2016 were cases...
August 2018: Medical Care
Daniel R Malcom
BACKGROUND AND PURPOSE: Ethical decision-making is one of the foundational elements of responsible patient care, yet traditional didactic coursework often misses the nuances of specific situational aspects of ethics as well as the impact of individual patient experiences on their perspective related to health care. The purpose of this study was to assess the impact of a clinical research ethics elective course involving a group reading experience and facilitated discussion on student decision-making and perspective on questions related to ethics...
May 2018: Currents in Pharmacy Teaching & Learning
Rebecca M Hoover, Melissa L Hunter, Kem P Krueger
INTRODUCTION: A survey of drug information specialists from academic drug information centers in the United States was conducted to identify faculty workload, operational characteristics of the center, and contribution of those faculty and centers to pharmacy education. METHODS: A 32-item survey was administered to drug information specialists and pharmacy college/school deans. Faculty workload items included age, credentials, training, and responsibilities. Center operational items identified clients, number of requests, staffing structure, and funding source...
May 2018: Currents in Pharmacy Teaching & Learning
Kali VanLangen, Greg Wellman
INTRODUCTION: Electronic health records (EHRs) are used extensively throughout health systems; this indicates a need for pharmacy student competencies prior to pharmacy practice experiences. The objective was to determine current utility, perceived benefit, and future plans for EHR use in the didactic curriculum of doctor of pharmacy programs in the United States. METHODS: An electronic survey was distributed to members of two special interest groups through the American Association of Colleges of Pharmacy...
May 2018: Currents in Pharmacy Teaching & Learning
Ahmet S Boşnak, Nevzat Birand, Ömer Diker, Abdikarim Abdi, Bilgen Başgut
Background Clinical pharmacists have important roles in implementing scientifically valid knowledge and advice on safe, reasonable use of pharmaceuticals. Clinical pharmacy services were introduced and evaluated in oncology clinic in a tertiary university hospital. Methods A prospective interventional study was conducted from November 2017 to March 2018. Drug-related problems were classified using the Pharmaceutical Care Network Europe drug-related problem classification tool v8.01. The main outcome measure is the proposed interventions aimed at identification of the drug-related problems, the role of the pharmacists in the resolution, and the rate of acceptance of these recommendations by physicians...
January 1, 2018: Journal of Oncology Pharmacy Practice
Kyle Strnad, Bethany R Shoulders, Pamela L Smithburger, Sandra L Kane-Gill
OBJECTIVE: To assess the impact of telepharmacy services in the acute care setting. DATA SOURCES: EMBase, MEDLINE, and SCOPUS database searches were performed through April 2018. STUDY SELECTION AND DATA EXTRACTION: PRISMA guidelines were applied for this systematic review. All English-language studies meeting the criteria of the following population, intervention, comparison, and outcome question were included: What impact does the provision of inpatient clinical pharmacy services delivered via telemedicine have on patient outcomes compared with standard of care? DATA SYNTHESIS: A total of 11 studies were identified for the acute care setting, including 3 for critically ill patients...
July 1, 2018: Annals of Pharmacotherapy
Catherine J Byrne, Caroline Walsh, Caitriona Cahir, Cristín Ryan, David J Williams, Kathleen Bennett
OBJECTIVES: The Drug Burden Index (DBI) tool quantifies individual exposure to anticholinergic and sedative medications. The DBI has been internationally validated against adverse health outcomes in older people. DBI exposure has not been reported in the Irish older population. This study aimed to: (1) develop a list of drugs with clinically significant anticholinergic and/or sedative effects (DBI medications) relevant to Ireland; (2) examine, using the DBI formula, the prevalence of exposure to DBI medications in Irish older people and (3) explore patient factors associated DBI exposure...
July 6, 2018: BMJ Open
Robert Bryant, Betty Chaar, Carl Schneider
BACKGROUND: In the last decade interdisciplinary teamwork and collaboration are increasingly favoured as strategies to improve healthcare delivery. The need for collaboration is especially evident in acute care medical-surgical wards of hospitals. Doctors, nurses, pharmacists, doctors and other healthcare professionals work in shifts to provide a multiplicity of services to a rapidly changing caseload of patients. Traditionally, pharmacists have been assigned to a ward or wards for which they provided all clinical services...
April 12, 2018: International Journal of Nursing Studies
Chelsea Phillips Renfro, Michael Patti, Jordan M Ballou, Stefanie P Ferreri
OBJECTIVES: To develop a common language for the medication synchronization process in community pharmacies. METHODS: A systematic and iterative process was used to create and refine a common language for medication synchronization. First, a review of all available medication synchronization-related documents was completed. Second, a systematic scoping literature review was conducted to determine what core components of medication synchronization have been implemented by community pharmacies...
July 3, 2018: Journal of the American Pharmacists Association: JAPhA
Nicholas M Fusco, Kelly Foltz-Ramos
The purpose of this study was to evaluate the effects of interprofessional high-fidelity simulation-based learning (SBL) on third-year pharmacy and senior nursing students' perceptions of interprofessional care. Students participated in an interprofessional high-fidelity SBL experience consisting of two hospital-based scenarios followed by a debriefing. The "Student Perceptions of Interprofessional Clinical Education-Revised" (SPICE-R) instrument was administered pre- and post-SBL. The "Student Satisfaction and Self-Confidence in Learning" (SSSCL) instrument, which uses a 5-point Likert scale, was administered post-SBL...
July 6, 2018: Journal of Interprofessional Care
Guy Shalom, Devy Zisman, Meir Babaev, Amir Horev, Shmuel Tiosano, Yochai Schonmann, Doron Comaneshter, Arnon D Cohen
BACKGROUND: Updated data regarding the epidemiology of psoriasis and related healthcare utilization are lacking. OBJECTIVE: To investigate the epidemiology, comorbidities, healthcare services utilization, and drug use in a large group of patients with psoriasis from Clalit Health Services (CHS) database. METHODS: A controlled cross-sectional study was performed. Case patients were defined when there was at least one documented diagnosis of psoriasis registered by a CHS dermatologist between the years 1998-2016...
July 6, 2018: International Journal of Dermatology
J D Gatwood, M Chisholm-Burns, R Davis, F Thomas, P Potukuchi, A Hung, C P Kovesdy
AIM: To determine the association of adherence to oral antidiabetes medication with macrovascular and microvascular complications, time to insulin therapy, revascularization, admissions, and death among veterans with uncomplicated diabetes. METHODS: This was a retrospective cohort study using the Veterans Affairs Corporate Data Warehouse to examine 159 032 veterans diagnosed with uncomplicated diabetes during 2002-2014 and starting oral antidiabetes therapy for the first time...
July 6, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
Grzegorz M Rdzak, Laura M Whitman, Silvio E Inzucchi
Persistent elevation of thyroid stimulating hormone (TSH) is a common clinical problem in outpatient clinics treating patients with primary hypothyroidism. One challenge to practitioners involves predicaments where patients have an inadequate response to a seemingly appropriate dose of levothyroxine (L-T4). A patient's self-assessed compliance to hormone replacement therapy or verification refill history at the patient's pharmacy might not be a reliable form of confirmation of non-adherence to the drug by the patient, which has been referred to as "L-T4 pseudo-malabsorption...
July 2018: Therapeutic Advances in Endocrinology and Metabolism
Gabrielle Campbell, Wayne D Hall, Amy Peacock, Nicholas Lintzeris, Raimondo Bruno, Briony Larance, Suzanne Nielsen, Milton Cohen, Gary Chan, Richard P Mattick, Fiona Blyth, Marian Shanahan, Timothy Dobbins, Michael Farrell, Louisa Degenhardt
BACKGROUND: Interest in the use of cannabis and cannabinoids to treat chronic non-cancer pain is increasing, because of their potential to reduce opioid dose requirements. We aimed to investigate cannabis use in people living with chronic non-cancer pain who had been prescribed opioids, including their reasons for use and perceived effectiveness of cannabis; associations between amount of cannabis use and pain, mental health, and opioid use; the effect of cannabis use on pain severity and interference over time; and potential opioid-sparing effects of cannabis...
July 2018: Lancet. Public Health
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