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Clinical pharmacy

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https://www.readbyqxmd.com/read/28811151/proposed-model-for-translational-research-at-a-teaching-intensive-college-of-pharmacy
#1
Erin Ulrich, Sarah Grady, Jacqueline Vonderhaar, Andrew Ruplin
BACKGROUND: Many American colleges of pharmacy are small, private, teaching institutions. Faculty are required to maintain a research agenda, although the publication quota is less compared with their publicly funded college of pharmacy peers. Faculty at these smaller schools conduct research with very little internal or external funding. This tends to lead to smaller, less impactful research findings. Translational research is becoming popular for research faculty as it bridges theory to practice...
August 8, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28811089/physician-experiences-with-clinical-pharmacists-in-primary-care-teams
#2
Gerardo Moreno, Sarah Lonowski, Jeffrey Fu, Janet S Chon, Natalie Whitmire, Carolina Vasquez, Samuel A Skootsky, Douglas S Bell, Richard Maranon, Carol M Mangione
BACKGROUND: Improving medication management is an important component of comprehensive care coordination for health systems. The Managing Your Medication for Education and Daily Support (MyMeds) medication management program at the University of California Los Angeles addresses medication management issues by embedding trained clinical pharmacists in primary care practice teams. OBJECTIVES: The aim of this work was to examine and explore physician opinions about the clinical pharmacist program and identify common themes among physician experiences as well as barriers to integration of clinical pharmacists into primary care practice teams...
August 12, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28809188/clinical-supervision-of-interns-understanding-the-view-of-interns-and-the-potential-of-ict-to-deliver-supervision-for-safer-patient-care
#3
Kwang Chien Yee, Angela Madden, Rosie Nash, Michael Connolly
Clinical communication and clinical supervision of junior healthcare professionals are identified as the two most common preventable factors to reduce medical errors. While multiple strategies have been implemented to improve clinical communication, clinical supervision has not attracted as much attention. This is in part due to the lack of understanding of clinical supervision. Furthermore, there is a lack of exploration of information communication technology (ICT) in assisting the delivery of clinical supervision from the perspective of users (i...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28808580/the-detection-of-influenza-virus-at-the-community-pharmacy-to-improve-the-management-of-local-residents-with-influenza-or-influenza-like-disease
#4
Akio Kawachi, Yusuke Sakamoto, Shunya Mouri, Mitsuaki Fukumori, Riku Kawano, Takaya Murakami, Junichiro Sonoda, Keiko Narumi, Yoshihiro Shimodozono, Kenji Etoh, Susumu Chiyotanda, Takashi Furuie, Keizo Sato, Masao Fukumori, Toshiro Motoya
BACKGROUND: As of 2014, community pharmacies in Japan are approved by the Ministry of Health, Labour and Welfare to measure lipid panel, HbA1c, glucose, ALT, AST and γ-GTP, but not to screen for influenza virus. We provided influenza virus screening tests at a community pharmacy to triage people with symptoms suggestive of influenza. Participants were given appropriate advice on how to prevent the spread of and safeguard against influenza. We subsequently evaluated the effects of community pharmacy-based influenza virus screening and prevention measures...
2017: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/28804929/factors-moderating-the-relative-effectiveness-of-varenicline-and-nicotine-replacement-therapy-in-clients-using-smoking-cessation-services
#5
Neil Walker, Heather Gainforth, Vasiliki Kiparoglou, Hayley Robinson, Hugo van Woerden, Robert West
AIMS: To assess how far the greater effectiveness of varenicline over nicotine replacement therapy (NRT) is moderated by characteristics of the smokers or setting in clinical practice. DESIGN: We used observational data from 22,472 treatment episodes between 2013 and 2016 from smoking cessation services in England to assess whether differences between varenicline and NRT were moderated by a set of smoker and setting characteristics: these included level of social deprivation, age, gender, ethnic group, nicotine dependence, and treatment context...
August 13, 2017: Addiction
https://www.readbyqxmd.com/read/28804459/metabolic-variability-of-a-multispecies-probiotic-preparation-impacts-on-the-anti-inflammatory-activity
#6
Michele Biagioli, Luca Laghi, Adriana Carino, Sabrina Cipriani, Eleonora Distrutti, Silvia Marchianò, Carola Parolin, Paolo Scarpelli, Beatrice Vitali, Stefano Fiorucci
Background: In addition to strain taxonomy, the ability of probiotics to confer beneficial effects on the host rely on a number of additional factors including epigenetic modulation of bacterial genes leading to metabolic variability and might impact on probiotic functionality. Aims: To investigate metabolism and functionality of two different batches of a probiotic blend commercialized under the same name in Europe in models of intestinal inflammation. Methods: Boxes of VSL#3, a probiotic mixture used in the treatment of pouchitis, were obtained from pharmacies in UK subjected to metabolomic analysis and their functionality tested in mice rendered colitis by treatment with DSS or TNBS...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28799951/surface-engineered-blood-adsorption-device-for-hyperphosphatemia-treatment
#7
Quan Shi, Michael Jolly, Marian G Mccord, Melanie S Joy
Correspondence: Melanie S. Joy, PharmD, PhD, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Mail Stop C238, Room V20-4108, 12850 East Montview Blvd, Aurora, CO 80045. Email: Melanie.Joy@ucdenver.eduThe research employed surface engineering methods to develop, optimize, and characterize a novel textile-based hemoadsorption device for hyperphosphatemia in hemodialysis-dependent end-stage kidney disease. Phosphate adsorbent fabrics (PAFs) were prepared by thermopressing alumina powders to polyester filtration fabrics and treatment with trimesic acid (TMA)...
August 8, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28797023/assessing-antiretroviral-use-during-gaps-in-hiv-primary-care-using-multisite-medicaid-claims-and-clinical-data
#8
Anne K Monroe, John A Fleishman, Cindy C Voss, Jeanne C Keruly, Ank E Nijhawan, Allison L Agwu, Judith A Aberg, Richard M Rutstein, Richard D Moore, Kelly A Gebo
BACKGROUND: Some individuals who appear poorly retained by clinic visit-based retention measures are using antiretroviral therapy (ART) and maintaining viral suppression. We examined whether individuals with a gap in HIV primary care (≥180 days between HIV outpatient clinic visits) obtained ART during that gap after 180 days. SETTING: HIV Research Network data from 5 sites and Medicaid Analytic Extract eligibility and pharmacy data were combined. METHODS: Factors associated with having both an HIV primary care gap and a new (ie, nonrefill) ART prescription during a gap were evaluated with multinomial logistic regression...
September 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28795519/outcomes-costs-and-stakeholders-perspectives-associated-with-the-incorporation-of-community-pharmacy-services-into-the-national-health-insurance-system-in-thailand-a-systematic-review
#9
REVIEW
Narong Asayut, Phayom Sookaneknun, Surasak Chaiyasong, Kritsanee Saramunee
OBJECTIVES: Identify costs, outcomes and stakeholders' perspectives associated with incorporation of community pharmacy services into the Thai National Health Insurance System and their values to all stakeholders. METHODS: Using a combination of search terms, a comprehensive literature search was performed using the Thai Journal Citation Index Centre, Health System Research Institute database, PubMed and references from recent reviews. Identified studies were published between January 2000 and December 2014...
August 9, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28795461/impact-of-test-anxiety-on-pharmacy-students-performance-in-objective-structured-clinical-examination-a-cross-sectional-survey
#10
Muhammad A Hadi, Majid Ali, Abdul Haseeb, Mahmoud M A Mohamed, Mahmoud E Elrggal, Ejaz Cheema
OBJECTIVE: To assess the association between test-related anxiety and pharmacy students' performance in the Objective Structured Clinical Examination (OSCE). METHODS: A cross-sectional survey was conducted among Year-5 Doctor of Pharmacy (PharmD) students enrolled at a public university in Saudi Arabia. Students completed Test Anxiety Inventory (TAI), a 20-item validated questionnaire used to assess test-related anxiety, prior to the commencement of a summative OSCE...
August 10, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28793075/-coordination-between-pharmaceutical-services-for-integrated-pharmacotherapy-the-case-of-catalonia
#11
Karen Sarmento Costa, Moisés Goldbaum, Rafel Guayta-Escolies, Pilar Modamio, Eduardo Luis Mariño, José Luis Segú Tolsá
Pharmaceutical policies have been considered strategies to contribute to the guarantee of care coordination and clinical integration. This study sought to describe the pharmaceutical services developed at different levels of care in the health network in Catalonia, as well as to identify and analyze the mechanisms and instruments that act as facilitators and/or barriers to the coordination of pharmacotherapy. This is a descriptive study of 12 cases of hospital pharmacy services, primary care and community pharmacies...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28793065/infrastructure-evaluation-of-pharmaceutical-services-in-the-national-health-system-of-minas-gerais
#12
Mariana Michel Barbosa, Marina Morgado Garcia, Renata Cristina Rezende Macedo do Nascimento, Edna Afonso Reis, Augusto Afonso Guerra, Francisco De Assis Acurcio, Juliana Álvares
Objectives: To characterize the infrastructure of public pharmacies in Minas Gerais, comparing municipalities that have received the RFM program to the ones that haven't, in order to verify if the State's Economic Incentives implied in improvement of local Pharmaceutical Services (PS). Methods: A cross-sectional, exploratory, evaluative study in a representative sample of the municipalities of Minas Gerais. Face-to-face interviews were conducted with users, physicians, and drug dispensers, as well as observation of pharmacy facilities and telephone interviews with municipal officials from the PS...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28790076/implementation-of-a-formulary-management-process
#13
Lauren I Karel, Dennis R Delisle, Ellena A Anagnostis, Cindy J Wordell
PURPOSE: The application of lean methodology in an initiative to redesign the formulary maintenance process at an academic medical center is described. SUMMARY: Maintaining a hospital formulary requires clear communication and coordination among multiple members of the pharmacy department. Using principles of lean methodology, pharmacy department personnel within a multihospital health system launched a multifaceted initiative to optimize formulary management systemwide...
August 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28790075/implementation-of-a-pharmacist-managed-clinic-for-patients-with-chronic-nonmalignant-pain
#14
Jessica L Norman, Miranda E Kroehl, Huong Mindy Lam, Carmen L Lewis, Chelsea N Mitchell, Cindy L O'Bryant, Katy E Trinkley
PURPOSE: A pharmacist-managed chronic pain clinic (PMCPC) in a primary care setting is described. SUMMARY: As primary care providers (PCPs) may be unprepared or lack time to manage high-risk patients receiving opioids for chronic nonmalignant pain, alternative models of care are needed. The University of Colorado PMCPC is integrated into an internal medicine outpatient clinic. The PMCPC is staffed by 1 clinical pharmacist, with pharmacy students and residents also performing clinic duties...
August 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28789645/student-preparedness-characteristics-important-for-clinical-learning-perspectives-of-supervisors-from-medicine-pharmacy-and-nursing
#15
Hasini Banneheke, Vishna Devi Nadarajah, Srinivasan Ramamurthy, Afshan Sumera, Sneha Ravindranath, Kamalan Jeevaratnam, Benny Efendie, Leela Chellamuthu, Purushotham Krishnappa, Ray Peterson
BACKGROUND: Student perspectives of clinical preparedness have been studied in the literature, but the viewpoint of supervisors is limited. Hence, the aim was to examine the perspective of supervisors on the characteristics of health professional students important for preparedness for clinical learning. METHODS: This was a descriptive, questionnaire-based, cross-sectional study conducted at three higher education institutions in Malaysia. A previously published questionnaire with 62 characteristics was adopted with modifications after pre-testing...
August 8, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28783420/prescription-level-factors-associated-with-primary-nonadherence-to-dermatologic-medications
#16
Audrey Rutherford, Donald A Glass, Elizabeth A Suarez, Adewole S Adamson
PURPOSE: To analyze factors associated with primary nonadherence to dermatologic medications and study whether prescription-level factors are associated with primary nonadherence. MATERIAL AND METHODS: A retrospective review of medical records of new dermatology patients from January 2011 to December 2013 at a single urban safety-net hospital outpatient dermatology clinic with a closed pharmacy system. RESULTS: A total of 4307 prescriptions were written for 2490 patients...
August 7, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28779530/pharmacology-and-drug-development-in-rare-diseases-the-attractiveness-and-expertise-of-the-french-medical-pharmacology
#17
Joëlle Micallef, Pierre Boutouyrie, Olivier Blin
Developing drugs for rare disease can be challenging due to specific rare disease characteristics. The French Medical Pharmacology is structured and positioned to play a major role in Orphan Drug Research and Development due to the required expertise concentrated into pharmacology departments, exclusively implemented within the French University Hospitals, public hospitals that are linked to a medical school (and often a pharmacy school) with numerous INSERM or CNRS labelled research units. In addition, these structures allow a close collaboration between researchers, academic institutions and biotech start-up (most of them being spin-off of the academic structures)...
August 5, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28777308/key-challenges-in-the-search-for-innovative-drug-treatments-for-special-populations-converging-needs-in-neonatology-pediatrics-and-medical-genetics
#18
Stuart MacLeod
The explosion of knowledge concerning the interplay of genetic and environmental factors determining pathophysiology and guiding therapeutic choice has altered the landscape in pediatric clinical pharmacology and pharmacy. The need for innovative research methods and design expertise for small clinical trials to be undertaken in sparse populations has been accentuated. At the same time, shortfalls in critical human resources represent a key challenge, especially in low- and middle-income countries where the need for new research and education directions is greatest...
August 4, 2017: Children
https://www.readbyqxmd.com/read/28777133/medication-adherence-among-patients-with-apparent-treatment-resistant-hypertension-systematic-review-and-meta-analysis
#19
Hannah Durand, Peter Hayes, Eimear C Morrissey, John Newell, Monica Casey, Andrew W Murphy, Gerard J Molloy
OBJECTIVES: Medication nonadherence is a known behavioural contributor to poor blood pressure (BP) control that puts patients with hypertension at elevated cardiovascular risk. Studies of medication adherence for apparent treatment-resistant hypertension (aTRH) vary significantly with respect to design, methods, and setting, and, as a result, have produced highly variable figures describing the prevalence of nonadherence. This review aimed to describe the prevalence and potential moderators of medication nonadherence estimates for aTRH...
August 1, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28776320/cost-effectiveness-of-support-for-people-starting-a-new-medication-for-a-long-term-condition-through-community-pharmacies-an-economic-evaluation-of-the-new-medicine-service-nms-compared-with-normal-practice
#20
Rachel A Elliott, Lukasz Tanajewski, Georgios Gkountouras, Anthony J Avery, Nick Barber, Rajnikant Mehta, Matthew J Boyd, Asam Latif, Antony Chuter, Justin Waring
BACKGROUND: The English community pharmacy New Medicine Service (NMS) significantly increases patient adherence to medicines, compared with normal practice. We examined the cost effectiveness of NMS compared with normal practice by combining adherence improvement and intervention costs with the effect of increased adherence on patient outcomes and healthcare costs. METHODS: We developed Markov models for diseases targeted by the NMS (hypertension, type 2 diabetes mellitus, chronic obstructive pulmonary disease, asthma and antiplatelet regimens) to assess the impact of patients' non-adherence...
August 3, 2017: PharmacoEconomics
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