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https://www.readbyqxmd.com/read/28342970/not-in-one-metric-neuroticism-modulates-different-resting-state-metrics-within-distinctive-brain-regions
#1
Claudio Gentili, Ioana Alina Cristea, Emiliano Ricciardi, Nicola Vanello, Cristian Popita, Daniel David, Pietro Pietrini
INTRODUCTION: Neuroticism is a complex personality trait encompassing diverse aspects. Notably, high levels of neuroticism are related to the onset of psychiatric conditions, including anxiety and mood disorders. Personality traits are stable individual features; therefore, they can be expected to be associated with stable neurobiological features, including the Brain Resting State (RS) activity as measured by fMRI. Several metrics have been used to describe RS properties, yielding rather inconsistent results...
March 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28336919/altered-spontaneous-brain-activity-in-chronic-smokers-revealed-by-fractional-ramplitude-of-low-frequency-fluctuation-analysis-a-preliminary-study
#2
Chao Wang, Zhujing Shen, Peiyu Huang, Hualiang Yu, Wei Qian, Xiaojun Guan, Quanquan Gu, Yihong Yang, Minming Zhang
Although a substantial body of previous functional magnetic resonance imaging (fMRI) studies have revealed different brain responses to external stimuli in chronic cigarette smokers compared with nonsmokers, only a few studies assessed brain spontaneous activity in the resting state in chronic smokers. The aim of this study was to investigate alterations of brain activity during the resting state in chronic smokers using fractional amplitude of low-frequency fluctuation (fALFF). In the present study, 55 smokers and 49 healthy nonsmokers were included...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28319755/repetitive-transcranial-magnetic-stimulation-rtms-of-the-dorsolateral-prefrontal-cortex-reduces-resting-state-insula-activity-and-modulates-functional-connectivity-of-the-orbitofrontal-cortex-in-cigarette-smokers
#3
Xingbao Li, Lian Du, Gregory L Sahlem, Bashar W Badran, Scott Henderson, Mark S George
BACKGROUND: Previous studies reported that repetitive transcranial magnetic stimulation (rTMS) can reduce cue-elicited craving and decrease cigarette consumption in smokers. The mechanism of this effect however, remains unclear. We used resting-state functional magnetic resonance imaging (rsfMRI) to test the effect of rTMS in non-treatment seeking smokers. METHODS: We used a single blinded, sham-controlled, randomized counterbalanced crossover design where participants underwent two visits separated by at least 1 week...
February 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28299208/sensorimotor-cortical-neuroplasticity-in-the-early-stage-of-bell-s-palsy
#4
Wenwen Song, Minhui Dai, Lihua Xuan, Zhijian Cao, Sisi Zhou, Courtney Lang, Kun Lv, Maosheng Xu, Jian Kong
Neuroplasticity is a common phenomenon in the human brain following nerve injury. It is defined as the brain's ability to reorganize by creating new neural pathways in order to adapt to change. Here, we use task-related and resting-state fMRI to investigate neuroplasticity in the primary sensory (S1) and motor cortex (M1) in patients with acute Bell's palsy (BP). We found that the period directly following the onset of BP (less than 14 days) is associated with significant decreases in regional homogeneity (ReHo), fractional amplitude of low frequency fluctuations (fALFF), and intrinsic connectivity contrast (ICC) values in the contralateral S1/M1 and in ReHo and ICC values in the ipsilateral S1/M1, compared to healthy controls...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28297595/decreased-resting-state-activity-in-the-precuneus-is-associated-with-depressive-episodes-in-recurrent-depression
#5
Chun-Hong Liu, Xin Ma, Zhen Yuan, Lu-Ping Song, Bing Jing, Hong-Yu Lu, Li-Rong Tang, Jin Fan, Martin Walter, Cun-Zhi Liu, Lihong Wang, Chuan-Yue Wang
OBJECTIVE: To investigate alterations in resting-state spontaneous brain activity in patients with major depressive disorder (MDD) experiencing multiple episodes. METHODS: Between May 2007 and September 2014, 24 recurrent and 22 remitted patients diagnosed with MDD with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), and 69 healthy controls matched for age, sex, and educational level participated in this study. Among them, 1 healthy control was excluded due to excessive head motion...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28257930/regional-homogeneity-resting-state-functional-connectivity-and-amplitude-of-low-frequency-fluctuation-associated-with-creativity-measured-by-divergent-thinking-in-a-sex-specific-manner
#6
Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Takamitsu Shinada, Kohei Sakaki, Takayuki Nozawa, Shigeyuki Ikeda, Susumu Yokota, Magistro Daniele, Yuko Sassa, Ryuta Kawashima
Brain connectivity is traditionally thought to be important for creativity. Here we investigated the associations of creativity measured by divergent thinking (CMDT) with resting-state functional magnetic imaging (fMRI) measures and their sex differences. We examined these relationships in the brains of 1277 healthy young adults. Whole-brain analyses revealed a significant interaction between verbal CMDT and sex on (a) regional homogeneity within an area from the left anterior temporal lobe (b) on the resting state functional connectivity (RSFC) between the mPFC and the left inferior frontal gyrus and (c) on fractional amplitude of low frequency fluctuations (fALFF) in several distinct areas, including the precuneus and middle cingulate gyrus, left middle temporal gyrus, right middle frontal gyrus, and cerebellum...
February 28, 2017: NeuroImage
https://www.readbyqxmd.com/read/28249785/identifying-the-presence-of-parkinson-s-disease-using-low-frequency-fluctuations-in-bold-signals
#7
Yan Tang, Li Meng, Chang-Min Wan, Zhen-Hua Liu, Wei-Hua Liao, Xin-Xiang Yan, Xiao-Yu Wang, Bei-Sha Tang, Ji-Feng Guo
Parkinson's disease (PD) is a chronic, progressive, and degenerative neurological disorder that is characterized by the degeneration of dopamine neurons in the substantia nigra and the formation of intracellular Lewy inclusion bodies. Resting-state functional magnetic resonance imaging (RS-fMRI) has demonstrated evidence of changes in metabolic patterns in individuals with PD. The purpose of this study was to determine whether the presence of PD could be "predicted" based on resting fluctuations in the blood oxygenation level dependent signal...
February 27, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28199371/the-value-of-resting-state-functional-magnetic-resonance-imaging-for-detecting-epileptogenic-zones-in-patients-with-focal-epilepsy
#8
Zhijuan Chen, Yang An, Bofeng Zhao, Weidong Yang, Qing Yu, Li Cai, Hongyan Ni, Jianzhong Yin
OBJECTIVE: To determine the value of resting-state functional magnetic resonance imaging (RS-fMRI) based on the local analysis methods regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF), and fractional ALFF (fALFF), for detecting epileptogenic zones (EZs). METHODS: A total of 42 consecutive patients with focal epilepsy were enrolled. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of visually assessed RS-fMRI, MRI, magnetic resonance spectroscopy (MRS), video electroencephalography (VEEG), and positron-emission tomography computed tomography (PET-CT) in EZ localization were evaluated to assess their diagnostic abilities...
2017: PloS One
https://www.readbyqxmd.com/read/28192860/amplitude-of-low-frequency-fluctuations-during-resting-state-differentially-predicts-authentic-and-hubristic-pride
#9
Feng Kong, Qiaolin He, Xiqin Liu, Xiayu Chen, Xu Wang, Jingjing Zhao
OBJECTIVE: Pride is an important self-conscious emotion and comprised of two distinct conceptual facets: arrogant, egotistic "hubristic pride", and pro-social, achievement-oriented "authentic pride". However, little is known about the neural basis of two facets of pride. Here we investigated the association between spontaneous brain activity and these two facets of pride in resting state. METHOD: We measured 276 participants on authentic and hubristic pride. The fractional amplitude of low frequency fluctuations (fALFF) was used to identify pride-related regions...
February 13, 2017: Journal of Personality
https://www.readbyqxmd.com/read/28174129/intrinsic-cerebral-activity-at-resting-state-in-adults-with-major-depressive-disorder-a-meta-analysis
#10
Ming Zhou, Xinyu Hu, Lu Lu, Lianqing Zhang, Lizhou Chen, Qiyong Gong, Xiaoqi Huang
Numerous neuroimaging studies have been undertaken to detect cerebral intrinsic activity in major depressive disorder (MDD) with resting state fMRI (rs-fMRI). However, the inconsistent results have hindered our understanding of the exact neuropathology related to MDD. The current meta-analysis used state-of-the-art conjunction analysis techniques to systematically review and summarize all available neuroimaging studies using rs-fMRI with amplitude of low frequency fluctuation (ALFF) and/or fractional ALFF (fALFF) on MDD patients and further explored the effect of antidepressants on the intrinsic activity of the brain...
April 3, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28158166/abnormal-local-brain-activity-beyond-the-pain-matrix-in-postherpetic-neuralgia-patients-a-resting-state-functional-mri-study
#11
Song Cao, Ganjun Song, Yi Zhang, Peng Xie, Ye Tu, Ying Li, Tian Yu, Buwei Yu
BACKGROUND: Postherpetic neuralgia (PHN) patients suffer debilitating chronic pain, hyperalgesia, and allodynia, as well as emotional disorders such as insomnia, anxiety, and depression. The brain structure and functional basis of PHN are still not fully understood. OBJECTIVES: To identify the changes of regional brain activity in resting-state PHN patients using regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) methods. Correlations between spontaneous pain intensity and ReHo or fALFF were analyzed...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28139359/altered-amplitude-of-low-frequency-fluctuations-in-schizophrenia-patients-with-persistent-auditory-verbal-hallucinations
#12
Anna Alonso-Solís, Yolanda Vives-Gilabert, Maria J Portella, Mireia Rabella, Eva M Grasa, Alexandra Roldán, Alejandro Keymer-Gausset, Conrad Molins, Fidel Núñez-Marín, Beatriz Gómez-Ansón, Enric Alvarez, Iluminada Corripio
The aim of this study is to analyze the differences in low frequency fluctuation (LFF) values between schizophrenia patients with and without auditory verbal hallucinations (AVH). Nineteen schizophrenia patients with persistent AVH (HP), fourteen non-hallucinating schizophrenia patients (nHP) and twenty healthy controls (HC) underwent R-fMRI. LFF values were calculated in the slow frequency band (0.01-0.08Hz). By means of group level contrasts, we performed direct voxel-wise group comparisons. Both groups of patients showed decreased amplitude LFF (ALFF) values in the occipital pole and lingual gyrus compared to HC, whereas increased ALFF values were found in the temporal pole and fusifom gyrus...
January 28, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28117505/age-associated-patterns-in-gray-matter-volume-cerebral-perfusion-and-bold-oscillations-in-children-and-adolescents
#13
Signe Bray
Healthy brain development involves changes in brain structure and function that are believed to support cognitive maturation. However, understanding how structural changes such as grey matter thinning relate to functional changes is challenging. To gain insight into structure-function relationships in development, the present study took a data driven approach to define age-related patterns of variation in gray matter volume (GMV), cerebral blood flow (CBF) and blood-oxygen level dependent (BOLD) signal variation (fractional amplitude of low-frequency fluctuations; fALFF) in 59 healthy children aged 7-18 years, and examined relationships between modalities...
January 24, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28104431/abnormal-regional-spontaneous-neuronal-activity-associated-with-symptom-severity-in-treatment-naive-patients-with-obsessive-compulsive-disorder-revealed-by-resting-state-functional-mri
#14
Linlin Qiu, Xiangshuai Fu, Shuai Wang, Qunfeng Tang, Xingui Chen, Lin Cheng, Fuquan Zhang, Zhenhe Zhou, Lin Tian
A large number of neuroimaging studies have revealed the dysfunction of brain activities in obsessive-compulsive disorder (OCD) during various tasks. However, regional spontaneous activity abnormalities in OCD are gradually being revealed. In this current study, we aimed to investigate cerebral regions with abnormal spontaneous activity using resting-state functional magnetic resonance imaging (fMRI) and further explored the relationship between the spontaneous neuronal activity and symptom severity of patients with OCD...
January 16, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28098938/towards-prognostic-biomarkers-from-bold-fluctuations-to-differentiate-a-first-epileptic-seizure-from-new-onset-epilepsy
#15
Lalit Gupta, Rick Janssens, Mariëlle C G Vlooswijk, Rob P W Rouhl, Anton de Louw, Albert P Aldenkamp, Shrutin Ulman, René M H Besseling, Paul A M Hofman, Vivianne H van Kranen-Mastenbroek, Danny M Hilkman, Jacobus F A Jansen, Walter H Backes
OBJECTIVE: The diagnosis of epilepsy cannot be reliably made prior to a patient's second seizure in most cases. Therefore, adequate diagnostic tools are needed to differentiate subjects with a first seizure from those with a seizure preceding the onset of epilepsy. The objective was to explore spontaneous blood oxygen level-dependent (BOLD) fluctuations in subjects with a first-ever seizure and patients with new-onset epilepsy (NOE), and to find characteristic biomarkers for seizure recurrence after the first seizure...
January 18, 2017: Epilepsia
https://www.readbyqxmd.com/read/28094810/aberrant-development-of-intrinsic-brain-activity-in-a-rat-model-of-caregiver-maltreatment-of-offspring
#16
C-G Yan, M Rincón-Cortés, C Raineki, E Sarro, S Colcombe, D N Guilfoyle, Z Yang, S Gerum, B B Biswal, M P Milham, R M Sullivan, F X Castellanos
Caregiver maltreatment induces vulnerability to later-life psychopathology. Clinical and preclinical evidence suggest changes in prefrontal and limbic circuitry underlie this susceptibility. We examined this question using a rat model of maternal maltreatment and methods translated from humans, resting-state functional magnetic resonance imaging (R-fMRI). Rat pups were reared by mothers provided with insufficient or abundant bedding for nest building from postnatal (PN) days 8 to 12 and underwent behavioral assessments of affect-related behaviors (forced swim, sucrose preference and social interaction) in adolescence (PN45) and early adulthood (PN60)...
January 17, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28077184/abnormalities-in-the-effective-connectivity-of-visuothalamic-circuitry-in-schizophrenia
#17
S J Iwabuchi, L Palaniyappan
BACKGROUND: Sensory-processing deficits appear crucial to the clinical expression of symptoms of schizophrenia. The visual cortex displays both dysconnectivity and aberrant spontaneous activity in patients with persistent symptoms and cognitive deficits. In this paper, we examine visual cortex in the context of the remerging notion of thalamic dysfunction in schizophrenia. We examined specific regional and longer-range abnormalities in sensory and thalamic circuits in schizophrenia, and whether these patterns are strong enough to discriminate symptomatic patients from controls...
January 12, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28077120/altered-fractional-amplitude-of-low-frequency-fluctuation-associated-with-cognitive-dysfunction-in-first-episode-drug-na%C3%A3-ve-major-depressive-disorder-patients
#18
Manli Huang, Shaojia Lu, Liang Yu, Lingjiang Li, Peng Zhang, Jianbo Hu, Weihua Zhou, Shaohua Hu, Ning Wei, Jinwen Huang, Jian Weng, Yi Xu
BACKGROUND: Previous studies have demonstrated that abnormities of both resting-state brain activity and cognitive dysfunction are frequently observed in patients with major depressive disorder (MDD). However, the underlying relationship between these two aspects is less investigated. In this context, the aim of the present study was to investigate the association between cognitive dysfunction and altered resting-state brain function in first-episode drug-naïve MDD patients. METHODS: Twenty-five drug-naïve MDD patients and twenty-six age-, sex-, and education-matched normal controls were recruited in this study...
January 11, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28057091/-resting-state-functional-magnetic-resonance-study-of-brain-function-changes-after-tips-operation-in-patients-with-liver-cirrhosis
#19
C Liu, H B Wang, Y Q Yu, M Q Wang, G B Zhang, L Y Xu, J M Wu
Objective: To investigate the brain function changes in cirrhosis patients after transjugular intrahepatic portosystemic shunt (TIPS), resting-state functional MRI (rs-fMRI) performed and fractional amplitude of low frequency fluctuation (fALFF) was analyzed. Methods: From January 2014 to February 2016, a total of 96 cirrhotic patients from invasive technology department and infection department in the First Affiliated Hospital of Anhui Medical University were selected , the blood ammonia data of 96 cirrhotic patients with TIPS operation in four groups were collected after 1, 3, 6 and 12 month, and all subjects performed rs-fMRI scans...
December 20, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28048305/su-f-j-139-amplitude-of-low-frequency-fluctuation-alff-and-regional-homogeneity-reho-study-of-the-respiration-motion-control-byhypnosis
#20
Y Liu, R Li, Y Xie
PURPOSE: Respiration control by hypnosis is a method in reducing the detriment to the healthy organs or organizations for patients during radiotherapy, especially for lung and abdomen cancer (Fig.1). It's hypothesized that there exists alterations neurological brain activity during the hypnosis state of respiratory motion control in comparison with resting state. METHODS: Thirteen healthy volunteers were organized to participate in a hypnosis experiment that consisted of two sectional scans of functional magnetic resonance imaging (fMRI), rest state condition (RSC) scanning and hypnosis state condition (HSC) scanning...
June 2016: Medical Physics
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