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https://www.readbyqxmd.com/read/28577332/hippocampal-fractional-amplitude-of-low-frequency-fluctuation-and-functional-connectivity-changes-in-premenstrual-syndrome
#1
Gaoxiong Duan, Huimei Liu, Yong Pang, Peng Liu, Yanfei Liu, Geliang Wang, Hai Liao, Lijun Tang, Wenfu Chen, Xiaping Mo, Danhong Wen, Hua Lin, Demao Deng
PURPOSE: To investigate differences in hippocampal activity between premenstrual syndrome (PMS) patients and healthy controls, to elucidate the neural mechanisms of PMS. MATERIALS AND METHODS: Twenty female patients with PMS (PMS group) and 21 healthy controls (HC group) underwent a single-shot gradient-recalled echo planar imaging (EPI) sequence scan during the luteal phase in 3.0 Tesla MRI. Spontaneous neural activity in hippocampus (HIPP) was measured by fractional amplitude of low-frequency fluctuation (fALFF)...
June 3, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28570868/fractional-amplitude-of-low-frequency-fluctuations-is-disrupted-in-alzheimer-s-disease-with-depression
#2
Zhongwei Guo, Xiaozheng Liu, Jiapeng Li, Fuquan Wei, Hongtao Hou, Xingli Chen, Xinwei Li, Wei Chen
OBJECTIVE: To explore brain activity in AD with depression (D-AD) based on fractional amplitude of low-frequency fluctuation (fALFF). METHODS: Twenty-two D-AD and 21 AD without depression patients (nD-AD) were examined by magnetic resonance imaging during resting state. Neuropsychiatric Inventory and Hamilton Depression Rating Scale were employed to assess the severity of depression. We analysed the characteristics of fALFF in D-AD differing from nD-AD. We also examined the correlation between fALFF and the depression severity...
July 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28559191/hope-and-the-brain-trait-hope-mediates-the-protective-role-of-medial-orbitofrontal-cortex-spontaneous-activity-against-anxiety
#3
Song Wang, Xin Xu, Ming Zhou, Taolin Chen, Xun Yang, Guangxiang Chen, Qiyong Gong
As a central research topic in the field of positive psychology, hope refers to an individual's goal-oriented expectations that include both agency thinking (i.e., the motivation to initiate and sustain actions to achieve goals) and pathway thinking (i.e., the capacity to find ways toward goals). Evidence from many previous studies has shown the role of hope in protecting against anxiety. However, little is known about the neurobiological basis of hope and the underlying mechanism that how hope reduces anxiety in the brain...
May 27, 2017: NeuroImage
https://www.readbyqxmd.com/read/28553253/resting-state-fmri-associated-with-stop-signal-task-performance-in-healthy-middle-aged-and-elderly-people
#4
Hsing-Hao Lee, Shulan Hsieh
Several brain regions and connectivity networks may be altered as aging occurs. We are interested in investigating if resting-state functional magnetic resonance imaging (RS-fMRI) can also be valid as an indicator of individual differences in association with inhibition performance among aged (including middle-aged) people. Seventy-two healthy adults (40-77 years of age) were recruited. Their RS-fMRI images were acquired and analyzed via two cluster-analysis methods: local synchronization of spontaneous brain activity measured by regional homogeneity (ReHo) and fractional amplitude of low-frequency fluctuations (fALFF) of blood oxygenation level-dependent signals...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28550250/frequency-dependent-changes-in%C3%A2-the%C3%A2-amplitude-of-low-frequency-fluctuations-in-mild-cognitive-impairment-with-mild-depression
#5
Yuxia Li, Bin Jing, Han Liu, Yifan Li, Xuan Gao, Yongqiu Li, Bin Mu, Haikuo Yu, Jinbo Cheng, Peter B Barker, Hongxing Wang, Ying Han
BACKGROUND: Depression is a potential marker of preclinical Alzheimer's disease (AD). However, little is known about the abnormal characteristics revealed by resting-state functional magnetic resonance imaging (rs-fMRI) in mild cognitive impairment (MCI) subjects with depressive symptoms (MCI-d). OBJECTIVE: The study was to examine whether abnormalities in amplitudes of low-frequency oscillation occurred in MCI-d and tried to find the possible spectrum showed higher recognition ability to the diagnosis by utilizing functional MRI (fMRI)...
May 26, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28469197/neural-plasticity-in-amplitude-of-low-frequency-fluctuation-cortical-hub-construction-regional-homogeneity-resulting-from-working-memory-training
#6
Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Atsushi Sekiguchi, Yuka Kotozaki, Seishu Nakagawa, Carlos Makoto Miyauchi, Yuko Sassa, Ryuta Kawashima
Working memory training (WMT) induces changes in cognitive function and various neurological systems. Here, we investigated changes in recently developed resting state functional magnetic resonance imaging measures of global information processing [degree of the cortical hub, which may have a central role in information integration in the brain, degree centrality (DC)], the magnitude of intrinsic brain activity [fractional amplitude of low frequency fluctuation (fALFF)], and local connectivity (regional homogeneity) in young adults, who either underwent WMT or received no intervention for 4 weeks...
May 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28458114/altered-fractional-amplitude-of-low-frequency-fluctuation-in-premenstrual-syndrome-a-resting-state-fmri-study
#7
Hai Liao, Gaoxiong Duan, Peng Liu, Yanfei Liu, Yong Pang, Huimei Liu, Lijun Tang, Jien Tao, Danhong Wen, Shasha Li, Lingyan Liang, Demao Deng
BACKGROUND: Premenstrual syndrome (PMS) is becoming highly prevalent among female and is characterized by emotional, physical and behavior symptoms. Previous evidence suggested functional dysregulation of female brain was expected to be involved in the etiology of PMS. The aim of present study was to evaluate the alterations of spontaneous brain activity in PMS patients based on functional magnetic resonance imaging (fMRI). METHODS: 20 PMS patients and 21 healthy controls underwent resting-state fMRI scanning during luteal phase...
April 24, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28429352/difference-in-resting-state-fractional-amplitude-of-low-frequency-fluctuation-between-bipolar-depression-and-unipolar-depression-patients
#8
H-L Yu, W-B Liu, T Wang, P-Y Huang, L-Y Jie, J-Z Sun, C Wang, W Qian, M Xuan, Q-Q Gu, H Liu, F-L Zhang, M-M Zhang
OBJECTIVE: To investigate the difference in fractional amplitude of low-frequency fluctuation (fALFF) of localized brain activities in the resting-state between bipolar depression and unipolar depression patients and to find biological markers that differentiate the two groups of patients. PATIENTS AND METHODS: Thirteen patients with bipolar depression, 15 patients with unipolar depression, and 16 healthy control subjects that were matched in age and years of education were subjected to 3...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28428208/resting-state-seed-based-analysis-an-alternative-to-task-based-language-fmri-and-its-laterality-index
#9
K A Smitha, K M Arun, P G Rajesh, B Thomas, C Kesavadas
BACKGROUND AND PURPOSE: Language is a cardinal function that makes human unique. Preservation of language function poses a great challenge for surgeons during resection. The aim of the study was to assess the efficacy of resting-state fMRI in the lateralization of language function in healthy subjects to permit its further testing in patients who are unable to perform task-based fMRI. MATERIALS AND METHODS: Eighteen healthy right-handed volunteers were prospectively evaluated with resting-state fMRI and task-based fMRI to assess language networks...
April 20, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28384269/amplitude-of-low-frequency-fluctuations-in-first-episode-drug-na%C3%A3-ve-depressive-patients-a-5-year-retrospective-study
#10
Kerang Zhang, Zhifen Liu, Xiaohua Cao, Chunxia Yang, Yong Xu, Ting Xu, Cheng Xu, Zhi Yang
Despite different treatments and courses of illness, depressive symptoms appear similar in bipolar disorder (BD) and major depressive disorder (MDD), causing BD with an onset of depressive episode being frequently misdiagnosed as MDD, and leading to inappropriate treatment and poor clinical outcomes. Therefore, there is an urgent need to explore underlying neural basis to distinguish BD from MDD. The medical records of 80 first-episode, drug-naïve depressive patients with an initial diagnosis of MDD and illness duration of at least 5 years were reviewed retrospectively for this study...
2017: PloS One
https://www.readbyqxmd.com/read/28353559/hyperactivity-of-the-default-mode-network-in-first-episode-drug-naive-schizophrenia-at-rest-revealed-by-family-based-case-control-and-traditional-case-control-designs
#11
Wenbin Guo, Feng Liu, Jindong Chen, Renrong Wu, Lehua Li, Zhikun Zhang, Huafu Chen, Jingping Zhao
Abnormal regional activity and functional connectivity of the default-mode network (DMN) have been reported in schizophrenia. However, previous studies may have been biased by unmatched case-control design. To limit such bias, the present study used both the family-based case-control design and the traditional case-control design to investigate abnormal regional activity of the DMN in patients with schizophrenia at rest.Twenty-eight first-episode, drug-naive patients with schizophrenia, 28 age-, sex-matched unaffected siblings of the patients (family-based controls, FBC), and 40 healthy controls (HC) underwent resting-state functional magnetic resonance imaging (fMRI) scans...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28348521/intrinsic-brain-activity-responsible-for-sex-differences-in-shyness-and-social-anxiety
#12
Xun Yang, Ming Zhou, Sunima Lama, Lizhou Chen, Xinyu Hu, Song Wang, Taolin Chen, Yan Shi, Xiaoqi Huang, Qiyong Gong
Male and female show significant differences in important behavioral features such as shyness, yet the neural substrates of these differences remain poorly understood. Previous neuroimaging studies have demonstrated that both shyness and social anxiety in healthy subjects are associated with increased activation in the fronto-limbic and cognitive control areas. However, it remains unknown whether these brain abnormalities would be shared by different genders. Therefore, in the current study, we used resting-state fMRI (r-fMRI) to investigate sex differences in intrinsic cerebral activity that may contribute to shyness and social anxiety...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28342970/not-in-one-metric-neuroticism-modulates-different-resting-state-metrics-within-distinctive-brain-regions
#13
Claudio Gentili, Ioana Alina Cristea, Emiliano Ricciardi, Nicola Vanello, Cristian Popita, Daniel David, Pietro Pietrini
INTRODUCTION: Neuroticism is a complex personality trait encompassing diverse aspects. Notably, high levels of neuroticism are related to the onset of psychiatric conditions, including anxiety and mood disorders. Personality traits are stable individual features; therefore, they can be expected to be associated with stable neurobiological features, including the Brain Resting State (RS) activity as measured by fMRI. Several metrics have been used to describe RS properties, yielding rather inconsistent results...
June 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28336919/altered-spontaneous-brain-activity-in-chronic-smokers-revealed-by-fractional-ramplitude-of-low-frequency-fluctuation-analysis-a-preliminary-study
#14
Chao Wang, Zhujing Shen, Peiyu Huang, Hualiang Yu, Wei Qian, Xiaojun Guan, Quanquan Gu, Yihong Yang, Minming Zhang
Although a substantial body of previous functional magnetic resonance imaging (fMRI) studies have revealed different brain responses to external stimuli in chronic cigarette smokers compared with nonsmokers, only a few studies assessed brain spontaneous activity in the resting state in chronic smokers. The aim of this study was to investigate alterations of brain activity during the resting state in chronic smokers using fractional amplitude of low-frequency fluctuation (fALFF). In the present study, 55 smokers and 49 healthy nonsmokers were included...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28319755/repetitive-transcranial-magnetic-stimulation-rtms-of-the-dorsolateral-prefrontal-cortex-reduces-resting-state-insula-activity-and-modulates-functional-connectivity-of-the-orbitofrontal-cortex-in-cigarette-smokers
#15
Xingbao Li, Lian Du, Gregory L Sahlem, Bashar W Badran, Scott Henderson, Mark S George
BACKGROUND: Previous studies reported that repetitive transcranial magnetic stimulation (rTMS) can reduce cue-elicited craving and decrease cigarette consumption in smokers. The mechanism of this effect however, remains unclear. We used resting-state functional magnetic resonance imaging (rsfMRI) to test the effect of rTMS in non-treatment seeking smokers. METHODS: We used a single blinded, sham-controlled, randomized counterbalanced crossover design where participants underwent two visits separated by at least 1 week...
May 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28299208/sensorimotor-cortical-neuroplasticity-in-the-early-stage-of-bell-s-palsy
#16
Wenwen Song, Minhui Dai, Lihua Xuan, Zhijian Cao, Sisi Zhou, Courtney Lang, Kun Lv, Maosheng Xu, Jian Kong
Neuroplasticity is a common phenomenon in the human brain following nerve injury. It is defined as the brain's ability to reorganize by creating new neural pathways in order to adapt to change. Here, we use task-related and resting-state fMRI to investigate neuroplasticity in the primary sensory (S1) and motor cortex (M1) in patients with acute Bell's palsy (BP). We found that the period directly following the onset of BP (less than 14 days) is associated with significant decreases in regional homogeneity (ReHo), fractional amplitude of low frequency fluctuations (fALFF), and intrinsic connectivity contrast (ICC) values in the contralateral S1/M1 and in ReHo and ICC values in the ipsilateral S1/M1, compared to healthy controls...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28297595/decreased-resting-state-activity-in-the-precuneus-is-associated-with-depressive-episodes-in-recurrent-depression
#17
Chun-Hong Liu, Xin Ma, Zhen Yuan, Lu-Ping Song, Bing Jing, Hong-Yu Lu, Li-Rong Tang, Jin Fan, Martin Walter, Cun-Zhi Liu, Lihong Wang, Chuan-Yue Wang
OBJECTIVE: To investigate alterations in resting-state spontaneous brain activity in patients with major depressive disorder (MDD) experiencing multiple episodes. METHODS: Between May 2007 and September 2014, 24 recurrent and 22 remitted patients diagnosed with MDD with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), and 69 healthy controls matched for age, sex, and educational level participated in this study. Among them, 1 healthy control was excluded due to excessive head motion...
April 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28257930/regional-homogeneity-resting-state-functional-connectivity-and-amplitude-of-low-frequency-fluctuation-associated-with-creativity-measured-by-divergent-thinking-in-a-sex-specific-manner
#18
Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Takamitsu Shinada, Kohei Sakaki, Takayuki Nozawa, Shigeyuki Ikeda, Susumu Yokota, Magistro Daniele, Yuko Sassa, Ryuta Kawashima
Brain connectivity is traditionally thought to be important for creativity. Here we investigated the associations of creativity measured by divergent thinking (CMDT) with resting-state functional magnetic imaging (fMRI) measures and their sex differences. We examined these relationships in the brains of 1277 healthy young adults. Whole-brain analyses revealed a significant interaction between verbal CMDT and sex on (a) regional homogeneity within an area from the left anterior temporal lobe (b) on the resting state functional connectivity (RSFC) between the mPFC and the left inferior frontal gyrus and (c) on fractional amplitude of low frequency fluctuations (fALFF) in several distinct areas, including the precuneus and middle cingulate gyrus, left middle temporal gyrus, right middle frontal gyrus, and cerebellum...
February 28, 2017: NeuroImage
https://www.readbyqxmd.com/read/28249785/identifying-the-presence-of-parkinson-s-disease-using-low-frequency-fluctuations-in-bold-signals
#19
Yan Tang, Li Meng, Chang-Min Wan, Zhen-Hua Liu, Wei-Hua Liao, Xin-Xiang Yan, Xiao-Yu Wang, Bei-Sha Tang, Ji-Feng Guo
Parkinson's disease (PD) is a chronic, progressive, and degenerative neurological disorder that is characterized by the degeneration of dopamine neurons in the substantia nigra and the formation of intracellular Lewy inclusion bodies. Resting-state functional magnetic resonance imaging (RS-fMRI) has demonstrated evidence of changes in metabolic patterns in individuals with PD. The purpose of this study was to determine whether the presence of PD could be "predicted" based on resting fluctuations in the blood oxygenation level dependent signal...
April 3, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28199371/the-value-of-resting-state-functional-magnetic-resonance-imaging-for-detecting-epileptogenic-zones-in-patients-with-focal-epilepsy
#20
Zhijuan Chen, Yang An, Bofeng Zhao, Weidong Yang, Qing Yu, Li Cai, Hongyan Ni, Jianzhong Yin
OBJECTIVE: To determine the value of resting-state functional magnetic resonance imaging (RS-fMRI) based on the local analysis methods regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF), and fractional ALFF (fALFF), for detecting epileptogenic zones (EZs). METHODS: A total of 42 consecutive patients with focal epilepsy were enrolled. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of visually assessed RS-fMRI, MRI, magnetic resonance spectroscopy (MRS), video electroencephalography (VEEG), and positron-emission tomography computed tomography (PET-CT) in EZ localization were evaluated to assess their diagnostic abilities...
2017: PloS One
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