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https://www.readbyqxmd.com/read/28918240/contingency-management-treatment-in-cocaine-using-methadone-maintained-patients-with-and-without-legal-problems
#1
Meredith K Ginley, Carla J Rash, Todd A Olmstead, Nancy M Petry
BACKGROUND: Legal difficulties and cocaine use are prevalent in methadone maintenance patients, and they are related to one another, as well as to poor response to methadone treatment. Contingency management (CM) is efficacious for decreasing cocaine use, but the relation of CM treatment to criminal activities has rarely been studied. METHODS: This study evaluated whether baseline legal problems are related to subsequent substance use and illegal activities for cocaine using methadone maintained patients and whether CM differentially improves outcomes depending on baseline legal problems...
September 8, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28917128/application-of-ultra-high-performance-liquid-chromatography-coupled-with-ltq-orbitrap-mass-spectrometry-for-identification-confirmation-and-quantitation-of-illegal-adulterated-weight-loss-drugs-in-plant-dietary-supplements
#2
Qiaoyuan Cheng, Linjun Shou, Cen Chen, Shi Shi, Minghao Zhou
In this paper, an ultra-high-performance liquid chromatography coupled with linear ion trap quadrupole Orbitrap high resolution mass spectrometry (UHPLC-LTQ-Orbitrap HRMS) method was developed and validated for identification, confirmation and quantitation of illegal adulterated weight-loss drugs in plant dietary supplements. 13 wt-loss drugs were well separated by the gradient elution of 10mmol/L ammonium acetate - 0.05% formic acid H2O and acetonitrile at a flow rate of 0.2mL/min within 12min. The MS analysis was operated under the positive ion and in full MS/dd-MS(2) (data-dependent MS(2)) mode...
September 9, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28915291/cosmetic-practitioners-take-huge-risks-purchasing-and-administering-illegal-botulinum-toxin-drug-products
#3
Sheldon Bradshaw
In their article "Importing Injectables" in the September 2014 issue of the Journal of Drugs in Dermatology, Dr. Kenneth Beer and Karen Rothschild highlighted the possible harm to patients and practitioners from the use of unapproved botulinum toxin products - eg, Botox, Dysport, Xeomin, and Myobloc - and other cosmetic prescription drug products purchased from foreign or unlicensed suppliers.1 In the intervening years, the accuracy of their critique has been repeatedly demonstrated, as the dangers to patients' health, as well as to cosmetic practitioners' liberty, has only increased...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28913341/assessing-the-risk-of-a-canine-rabies-incursion-in-northern-australia
#4
Emily G Hudson, Victoria J Brookes, Michael P Ward
Rabies is a globally distributed virus that causes approximately 60,00 human deaths annually with >99% of cases caused by dog bites. Australia is currently canine rabies free. However, the recent eastward spread of rabies in the Indonesian archipelago has increased the probability of rabies entry into northern Australian communities. In addition, many northern Australian communities have large populations of free-roaming dogs, capable of maintaining rabies should an incursion occur. A risk assessment of rabies entry and transmission into these communities is needed to target control and surveillance measures...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28910188/sedative-and-analgesic-drugs-online-a-content-analysis-of-the-supply-and-demand-information-available-in-thailand
#5
Kanokporn Pinyopornpanish, Wichuda Jiraporncharoen, Kanittha Thaikla, Kulyapa Yoonut, Chaisiri Angkurawaranon
BACKGROUND: Evidence from other countries has suggested that many controlled drugs are also offered online, even though it is illegal to sell these drugs without a license. OBJECTIVES: To evaluate the current contents related to the supply and demand of sedatives and analgesic drugs available online in Thailand, with a particular focus on Facebook. METHODS: A team of reviewers manually searched for data by entering keywords related to analgesic drugs and sedatives...
September 14, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28905079/-falsified-medicines-in-parallel-trade
#6
REVIEW
Heide Muckenfuß
The number of falsified medicines on the German market has distinctly increased over the past few years. In particular, stolen pharmaceutical products, a form of falsified medicines, have increasingly been introduced into the legal supply chain via parallel trading. The reasons why parallel trading serves as a gateway for falsified medicines are most likely the complex supply chains and routes of transport. It is hardly possible for national authorities to trace the history of a medicinal product that was bought and sold by several intermediaries in different EU member states...
September 13, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28904262/biodegradation-of-volatile-organic-compounds-and-their-effects-on-biodegradability-under-co-existing-conditions
#7
Miho Yoshikawa, Ming Zhang, Koki Toyota
Volatile organic compounds (VOCs) are major pollutants that are found in contaminated sites, particularly in developed countries such as Japan. Various microorganisms that degrade individual VOCs have been reported, and genomic information related to their phylogenetic classification and VOC-degrading enzymes is available. However, the biodegradation of multiple VOCs remains a challenging issue. Practical sites, such as chemical factories, research facilities, and illegal dumping sites, are often contaminated with multiple VOCs...
September 12, 2017: Microbes and Environments
https://www.readbyqxmd.com/read/28903875/risk-assessment-of-the-entry-of-canine-rabies-into-papua-new-guinea-via-sea-and-land-routes
#8
Victoria J Brookes, Andy Keponge-Yombo, David Thomson, Michael P Ward
Canine-rabies is endemic in parts of Indonesia and continues to spread eastwards through the Indonesian archipelago. Papua New Guinea (PNG) has a land border with Papua Province, Indonesia, as well as logging and fishing industry connections throughout Asia. PNG has a Human Development Index of 0.505; therefore, an incursion of canine-rabies could have devastating impacts on human (7.5 million) and animal populations. Given the known difficulties of rabies elimination in resource-scarce environments, an incursion of rabies into PNG would also likely compromise the campaign for global elimination of rabies...
September 15, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28903088/on-line-two-dimensional-liquid-chromatography-based-on-skeleton-type-molecularly-imprinted-column-for-selective-determination-of-sulfonylurea-additive-in-chinese-patent-medicines-or-functional-foods
#9
Pengqi Guo, Xinya Xu, Guoning Chen, Kamran Bashir, Hua Shu, Yanhui Ge, Wanghui Jing, Zhimin Luo, Chun Chang, Qiang Fu
Substandard and counterfeit anti-diabetic medicines directly influence the health and impose a great danger to individual patients and to public health. Counterfeiting has become a serious and underreported problem in the pharmaceutical industry. There are a large number of counterfeit medicines flooded in anti-diabetic markets which effect human health directly and indirectly. Therefore, some novel analytical techniques are necessary to be established for detecting these counterfeit drugs. In this study, a novel skeleton type molecularly imprinted column was successfully prepared...
September 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28898781/thymus-atrophy-is-an-efficient-marker-of-illicit-treatment-with-dexamethasone-in-veal-calves-results-from-a-triennial-experimental-study
#10
Guia Benedetta Richelmi, Cristiana Maurella, Marzia Pezzolato, Mario Botta, Katia Varello, Danilo Pitardi, Elisa Baioni, Claudio Bellino, Antonio D'Angelo, Maria Caramelli, Elena Bozzetta
Glucocorticoids, used in a wide range of pathologies thank to their therapeutical properties, are also illegally used as growth-promoters in animal breeding even if the European Union regulates their use to protect consumers' health from the adverse effects of residues in food. The first aim of the study was to establish the applicability of two histological parameters - atrophy and cortex-medulla ratio - to detect glucocorticoids misuse in calves. The second aim was to concurrently test the potentiality of both parameters to discriminate between treated and untreated animals...
September 6, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28898303/-legal-illegal-and-legitimate-in-the-use-and-misuse-of-substances
#11
Leonardo Ghioldi
his article attempts to establish a dialogue between existing laws, their effectiveness and the controversy within the context of the popularization of substance use in the country. To this end, the origin of the criminalization of substance use and the contradictory positions that have been adopted in laws and court rulings are tracked. All this is confronted with the growing habit of psychoactive substance use among general population, which no laws and rulings have yet managed to in?uence.
November 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28898300/-marijuana-a-toxicological-approach
#12
Silvia Cortese
From an adult perspective, both marijuana and alcohol consumption are becoming natural. Among illegal substances, marijuana has disseminated all over the word and specially in Argentina. Thus, a scientifc approach towards this issue must be developed and we should spread what we know about toxicity and adverse effects, particularly among adolescents. The impact of this kind of toxic during the neurodevelopmental period, both in cognitive and impulse control areas, may involve negative consequences for users at a later age...
November 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28895828/new-caution-about-risk-adjustment-after-united-whistleblower-lawsuit
#13
Joseph Burns
Did UnitedHealthcare's risk adjustment department actually "turn on the gas," as one executive put it, in an illegal effort to increase revenue? That's the claim at the heart of two cases the federal Department of Justice brought this spring against the nation's largest health insurer. The industry is watching closely.
July 2017: Managed Care
https://www.readbyqxmd.com/read/28895615/-methamphetamine-use-in-central-germany-a-qualitative-study-on-consumer-groups-and-motives-from-the-experts-perspective
#14
Laura Hoffmann, Nadine Schumann, Matthias Richter
Background Methamphetamine is one of the most consumed illegal drugs worldwide. In Germany, Methamphetamine shows the highest rates of growth in comparison to other illegal substances in recent years. Particularly Central Germany has been struck by a high rise in consumption. International studies indicate that there is no specific group of people that can be identified as Methamphetamine users. Different consumption patterns in terms of Methamphetamine use can be identified within various social groups. This qualitative study will explore different consumer groups among methamphetamine users, their motives, and how they differ by drug addiction type...
September 11, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28893851/synthetic-cannabinoid-use-among-high-school-seniors
#15
Joseph J Palamar, Monica J Barratt, Leigh Coney, Silvia S Martins
OBJECTIVES: In this study, we examined the prevalence and correlates of current synthetic cannabinoid (SC) use among high school seniors in the United States. METHODS: Monitoring the Future, an annual nationally representative survey of high school seniors, began querying current (30-day) SC use in 2014. Data were examined from the 2 most recent cohorts (2014-2015; N = 7805). Prevalence of self-reported use was examined and differences in demographics and recency and frequency of other drug use was compared between current marijuana-only users and current SC (plus marijuana) users using χ(2) and generalized linear model using Poisson...
September 11, 2017: Pediatrics
https://www.readbyqxmd.com/read/28886589/role-of-fkbp51-in-the-modulation-of-the-expression-of-the-corticosteroid-receptors-in-bovine-thymus-following-glucocorticoid-administration
#16
L Starvaggi Cucuzza, B Biolatti, F E Scaglione, F T Cannizzo
The aim of this work was to study the transcriptional effects of glucocorticoids on corticosteroid hormone receptors, prereceptors (11β-hydroxysteroid dehydrogenase 1 and 2, 11β-HSD1 and 2), and chaperones molecules regulating intracellular trafficking of the receptors (FKBP51 and FKBP52) in thymus of veal calves. Moreover, the expression of FKBP51 and FKBP52 gene were investigated in beef cattle thymus. In the cervical thymus of veal calves, dexamethasone administration in combination with estradiol decreased FKBP51 expression (P < 0...
August 8, 2017: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/28883213/present-status-of-displaying-pharmaceutical-products-for-sale-on-flea-market-applications-for-smartphones-and-the-responses-to-illicit-selling-by-service-providers
#17
Keiko Kishimoto, Tomoe Takeuchi, Noriko Fukushima
  In Japan, a pharmacy or drug store license is required for selling pharmaceutical products. However, civilians without a pharmacy or drug store license are displaying pharmaceutical products for sale on a flea market application, which is illegal dealing. This study discussed the modality for implementing countermeasures for the illicit selling of pharmaceutical products. We extracted pharmaceutical products displayed for sale on three flea market applications (Mercari, Rakuma, Fril) on one day. One hundred and eighty-one pharmaceutical products were displayed (49 on Mercari, 86 on Rakuma, and 46 on Fril)...
September 5, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28878250/improving-understanding-of-the-functional-diversity-of-fisheries-by-exploring-the-influence-of-global-catch-reconstruction
#18
Kirsty L Nash, Reg A Watson, Benjamin S Halpern, Elizabeth A Fulton, Julia L Blanchard
Functional diversity is thought to enhance ecosystem resilience, driving research focused on trends in the functional composition of fisheries, most recently with new reconstructions of global catch data. However, there is currently little understanding of how accounting for unreported catches (e.g. small-scale and illegal fisheries, bycatch and discards) influences functional diversity trends in global fisheries. We explored how diversity estimates varied among reported and unreported components of catch in 2010, and found these components had distinct functional fingerprints...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28874079/migration-agency-and-the-sex-industry-practitioners-perspectives-on-foreign-sex-workers-in-turkey
#19
Omur Kaya, Edna Erez
The article presents the political, economic, and sociocultural factors that make Turkey an attractive destination for foreign sex workers, and reviews trends in official statistics of arrested traffickers, rescued victims, and deportation of migrant illegal sex workers. In-depth interviews of 20 law enforcement and nongovernmental organizations staff members, who in the course of their work come into close contact with foreign sex workers, shed light on the statistics. The interview data provide insights into the structure of the Turkish sex market, the factors that bring foreign women to work in this market, and the impact of legal reforms on the circumstances of foreign sex workers...
September 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28873089/tempo-and-rates-of-diversification-in-the-south-american-cichlid-genus-apistogramma-teleostei-perciformes-cichlidae
#20
Christelle Tougard, Carmen R García Dávila, Uwe Römer, Fabrice Duponchelle, Frédérique Cerqueira, Emmanuel Paradis, Bruno Guinand, Carlos Angulo Chávez, Vanessa Salas, Sophie Quérouil, Susana Sirvas, Jean-François Renno
Evaluating biodiversity and understanding the processes involved in diversification are noticeable conservation issues in fishes subject to large, sometimes illegal, ornamental trade purposes. Here, the diversity and evolutionary history of the Neotropical dwarf cichlid genus Apistogramma from several South American countries are investigated. Mitochondrial and nuclear markers are used to infer phylogenetic relationships between 31 genetically identified species. The monophyly of Apistogramma is suggested, and Apistogramma species are distributed into four clades, corresponding to three morphological lineages...
2017: PloS One
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