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https://www.readbyqxmd.com/read/27790597/knowledge-and-awareness-regarding-swine-influenza-a-h1n1-virus-infection-among-dental-professionals-in-india-a-systematic-review
#1
REVIEW
Ramandeep Singh Gambhir, Prabh Roohan Pannu, Tarun Nanda, Gagandeep Arora, Amanpreet Kaur
INTRODUCTION: Swine flu or Influenza A (H1N1) flu is the most recent of the pandemic disease that has affected the world's population. We, as health care providers should feel responsible for reducing the transmission of influenza. AIM: To conduct a systematic review of observational studies and to assess dental professionals' knowledge and awareness regarding swine flu. MATERIALS AND METHODS: Relevant cross-sectional observational studies were included in the systematic review to assess the level of knowledge and awareness regarding swine flu among dental professionals...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27759342/a-study-of-outbreak-of-swine-flu-h1n1-in-north-west-zone-of-rajasthan-current-status-2015
#2
Surendra Kumar
BACKROUND: The outbreak of H1N1 virus had previously reported in India during 2009 flu pandemic. In 2015, the outbreak became widespread throughout India. The states of Gujarat and Rajasthan are severely elected. We studied an outbreak of H1N1 Virus in north-west zone of Rajasthan 2015. OBJECTIVE: To demonstrate the current epidemiological scenario of swine flu (H1N1) in north-west zone of Rajasthan with different demographic factors. METHODS: We screened total 6390 patients...
July 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27741319/cross-neutralising-nanobodies-bind-to-a-conserved-pocket-in-the-hemagglutinin-stem-region-identified-using-yeast-display-and-deep-mutational-scanning
#3
Tiziano Gaiotto, Simon E Hufton
Cross-neutralising monoclonal antibodies against influenza hemagglutinin (HA) are of considerable interest as both therapeutics and diagnostic tools. We have recently described five different single domain antibodies (nanobodies) which share this cross-neutralising activity and suggest their small size, high stability, and cleft binding properties may present distinct advantages over equivalent conventional antibodies. We have used yeast display in combination with deep mutational scanning to give residue level resolution of positions in the antibody-HA interface which are crucial for binding...
2016: PloS One
https://www.readbyqxmd.com/read/27729839/identification-of-suitable-natural-inhibitor-against-influenza-a-h1n1-neuraminidase-protein-by-molecular-docking
#4
Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar
The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for overcoming the epidemics. Traditionally, different plant extracts of garlic, ginger, kalmegh, ajwain, green tea, turmeric, menthe, tulsi, etc. have been used as hopeful source of prevention and treatment of human influenza. The H1N1 virus contains an important glycoprotein, known as neuraminidase (NA) that is mainly responsible for initiation of viral infection and is essential for the life cycle of H1N1...
September 2016: Genomics & Informatics
https://www.readbyqxmd.com/read/27728655/clinical-profile-of-swine-flu-h1n1-study-of-60-cases
#5
S P Abiramy, K Vengadakrishnan, Priyadharshini, Aishwarya
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27647955/successfully-managing-swine-flu-h1n1-2015-and-the-way-ahead-the-rajasthan-model
#6
Amita Kashyap, Monika Rathore, Ashok Panagariya
No abstract text is available yet for this article.
July 2016: Annals of Neurosciences
https://www.readbyqxmd.com/read/27381724/learning-to-trust-flu-shots-quasi-experimental-evidence-from-the-2009-swine-flu-pandemic
#7
Jürgen Maurer, Katherine M Harris
This paper studies consumer learning in influenza vaccination decisions. We examine consumer learning in influenza vaccine demand within a reduced form instrumental variable framework that exploits differences in risk characteristics of different influenza viruses as a natural experiment to distinguish the effects of learning based on previous influenza vaccination experiences from unobserved heterogeneity. The emergence of a new virus strain (influenza A H1N1/09) during the 2009 'Swine flu' pandemic resulted in two different vaccines being recommended for distinct population subgroups with some people, who were not usually targeted by seasonal vaccination programs, being specifically recommended for the new Swine flu vaccine...
September 2016: Health Economics
https://www.readbyqxmd.com/read/27338141/the-swine-flu-vaccine-public-attitudes-and-researcher-interpretations-a-systematic-review-of-qualitative-research
#8
Benedicte Carlsen, Claire Glenton
BACKGROUND: During pandemics, health authorities may be uncertain about the spread and severity of the disease and the effectiveness and safety of available interventions. This was the case during the swine flu (H1N1) pandemic of 2009-2010, and governments were forced to make decisions despite these uncertainties. While many countries chose to implement wide scale vaccination programmes, few accomplished their vaccination goals. Many research studies aiming to explore barriers and facilitators to vaccine uptake have been conducted in the aftermath of the pandemic, including several qualitative studies...
2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27093541/entrapment-of-h1n1-influenza-virus-derived-conserved-peptides-in-plga-nanoparticles-enhances-t-cell-response-and-vaccine-efficacy-in-pigs
#9
Jagadish Hiremath, Kyung-il Kang, Ming Xia, Mohamed Elaish, Basavaraj Binjawadagi, Kang Ouyang, Santosh Dhakal, Jesus Arcos, Jordi B Torrelles, X Jiang, Chang Won Lee, Gourapura J Renukaradhya
Pigs are believed to be one of the important sources of emerging human and swine influenza viruses (SwIV). Influenza virus conserved peptides have the potential to elicit cross-protective immune response, but without the help of potent adjuvant and delivery system they are poorly immunogenic. Biodegradable polylactic-co-glycolic acid (PLGA) nanoparticle (PLGA-NP) based vaccine delivery system enhances cross-presentation of antigens by the professional antigen presenting cells. In this study, Norovirus P particle containing SwIV M2e (extracellular domain of the matrix protein 2) chimera and highly conserved two each of H1N1 peptides of pandemic 2009 and classical human influenza viruses were entrapped in PLGA-NPs...
2016: PloS One
https://www.readbyqxmd.com/read/27049316/-political-dimensions-of-an-epidemic-the-case-of-influenza-a-h1n1-in-the-argentine-press
#10
Anahi Sy, Hugo Spinelli
The current study addresses social representations of the influenza A (H1N1) epidemic in Argentina in 2009, in the country's mainstream newspapers. The methodology was twofold, qualitative and quantitative, with an analysis of two dimensions: the construction of the epidemic as an "object" (designation and characterization) and the sources of information in the news stories, seeking to identify the social actors involved in each case. The results show that designating the epidemic as "H1N1" rather than "swine flu" was a conscious political decision to exempt a hazardous form of livestock production from its role in the disease, while focusing responsibility on individual patients...
March 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27016770/adjuvant-effects-of-invariant-nkt-cell-ligand-potentiates-the-innate-and-adaptive-immunity-to-an-inactivated-h1n1-swine-influenza-virus-vaccine-in-pigs
#11
Varun Dwivedi, Cordelia Manickam, Santosh Dhakal, Basavaraj Binjawadagi, Kang Ouyang, Jagadish Hiremath, Mahesh Khatri, Jacquelyn Gervay Hague, Chang Won Lee, Gourapura J Renukaradhya
Pigs are considered as the source of some of the emerging human flu viruses. Inactivated swine influenza virus (SwIV) vaccine has been in use in the US swine herds, but it failed to control the flu outbreaks. The main reason has been attributed to lack of induction of strong local mucosal immunity in the respiratory tract. Invariant natural killer T (iNKT) cell is a unique T cell subset, and activation of iNKT cell using its ligand α-Galactosylceramide (α-GalCer) has been shown to potentiate the cross-protective immunity to inactivated influenza virus vaccine candidates in mice...
April 15, 2016: Veterinary Microbiology
https://www.readbyqxmd.com/read/26961277/human-temperatures-for-syndromic-surveillance-in-the-emergency-department-data-from-the-autumn-wave-of-the-2009-swine-flu-h1n1-pandemic-and-a-seasonal-influenza-outbreak
#12
Samantha F Bordonaro, Daniel C McGillicuddy, Francesco Pompei, Dmitriy Burmistrov, Charles Harding, Leon D Sanchez
BACKGROUND: The emergency department (ED) increasingly acts as a gateway to the evaluation and treatment of acute illnesses. Consequently, it has also become a key testing ground for systems that monitor and identify outbreaks of disease. Here, we describe a new technology that automatically collects body temperatures during triage. The technology was tested in an ED as an approach to monitoring diseases that cause fever, such as seasonal flu and some pandemics. METHODS: Temporal artery thermometers that log temperature measurements were placed in a Boston ED and used for initial triage vital signs...
2016: BMC Emergency Medicine
https://www.readbyqxmd.com/read/26848884/role-of-extracorporeal-membrane-oxygenation-in-adult-respiratory-failure-an-overview
#13
REVIEW
Suneesh Anand, Divya Jayakumar, Wilbert S Aronow, Dipak Chandy
Extracorporeal membrane oxygenation (ECMO) provides complete or partial support of the heart and lungs. Ever since its inception in the 1960s, it has been used across all age groups in the management of refractory respiratory failure and cardiogenic shock. While it has gained widespread acceptance in the neonatal and pediatric physician community, ECMO remains a controversial therapy for Acute Respiratory Distress Syndrome (ARDS) in adults. Its popularity was revived during the swine flu (H1N1) pandemic and advancements in technology have contributed to its increasing usage...
2016: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/26726811/adjuvanted-influenza-h1n1-vaccination-reveals-lymphoid-signatures-of-age-dependent-early-responses-and-of-clinical-adverse-events
#14
Olga Sobolev, Elisa Binda, Sean O'Farrell, Anna Lorenc, Joel Pradines, Yongqing Huang, Jay Duffner, Reiner Schulz, John Cason, Maria Zambon, Michael H Malim, Mark Peakman, Andrew Cope, Ishan Capila, Ganesh V Kaundinya, Adrian C Hayday
Adjuvanted vaccines afford invaluable protection against disease, and the molecular and cellular changes they induce offer direct insight into human immunobiology. Here we show that within 24 h of receiving adjuvanted swine flu vaccine, healthy individuals made expansive, complex molecular and cellular responses that included overt lymphoid as well as myeloid contributions. Unexpectedly, this early response was subtly but significantly different in people older than ∼35 years. Wide-ranging adverse clinical events can seriously confound vaccine adoption, but whether there are immunological correlates of these is unknown...
February 2016: Nature Immunology
https://www.readbyqxmd.com/read/26611769/increased-risk-of-a-h1n1-pdm09-influenza-infection-in-uk-pig-industry-workers-compared-to-a-general-population-cohort
#15
Ellen Fragaszy, David A Ishola, Ian H Brown, Joanne Enstone, Jonathan S Nguyen-Van-Tam, Robin Simons, Alexander W Tucker, Barbara Wieland, Susanna M Williamson, Andrew C Hayward, James L N Wood
BACKGROUND: Pigs are mixing vessels for influenza viral reassortment, but the extent of influenza transmission between swine and humans is not well understood. OBJECTIVES: To assess whether occupational exposure to pigs is a risk factor for human infection with human and swine-adapted influenza viruses. METHODS: UK pig industry workers were frequency-matched on age, region, sampling month, and gender with a community-based comparison group from the Flu Watch study...
July 2016: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/26511046/measured-voluntary-avoidance-behaviour-during-the-2009-a-h1n1-epidemic
#16
Jude Bayham, Nicolai V Kuminoff, Quentin Gunn, Eli P Fenichel
Managing infectious disease is among the foremost challenges for public health policy. Interpersonal contacts play a critical role in infectious disease transmission, and recent advances in epidemiological theory suggest a central role for adaptive human behaviour with respect to changing contact patterns. However, theoretical studies cannot answer the following question: are individual responses to disease of sufficient magnitude to shape epidemiological dynamics and infectious disease risk? We provide empirical evidence that Americans voluntarily reduced their time spent in public places during the 2009 A/H1N1 swine flu, and that these behavioural shifts were of a magnitude capable of reducing the total number of cases...
November 7, 2015: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/26424131/effect-of-sesamin-against-cytokine-production-from-influenza-type-a-h1n1-induced-peripheral-blood-mononuclear-cells-computational-and-experimental-studies
#17
Kanda Fanhchaksai, Kanchanok Kodchakorn, Peraphan Pothacharoen, Prachya Kongtawelert
In 2009, swine flu (H1N1) had spread significantly to levels that threatened pandemic influenza. There have been many treatments that have arisen for patients since the WHO first reported the disease. Although some progress in controlling influenza has taken place during the last few years, the disease is not yet under control. The development of new and less expensive anti-influenza drugs is still needed. Here, we show that sesamin from the seeds of the Thai medicinal plant Sesamum indicum has anti-inflammatory cytokines in human peripheral blood mononuclear cells (PBMCs) induced by 2009 influenza virus type A H1N1...
January 2016: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/26416814/inspecting-the-mechanism-a-longitudinal-analysis-of-socioeconomic-status-differences-in-perceived-influenza-risks-vaccination-intentions-and-vaccination-behaviors-during-the-2009-2010-influenza-pandemic
#18
Jürgen Maurer
BACKGROUND: Influenza vaccination is strongly associated with socioeconomic status, but there is only limited evidence on the respective roles of socioeconomic differences in vaccination intentions versus corresponding differences in follow-through on initial vaccination plans for subsequent socioeconomic differences in vaccine uptake. METHODS: Nonparametric mean smoothing, linear regression, and probit models were used to analyze longitudinal survey data on perceived influenza risks, behavioral vaccination intentions, and vaccination behavior of adults during the 2009-2010 influenza A/H1N1 ("swine flu") pandemic in the United States...
October 2016: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/26384378/death-toll-from-swine-flu-in-india-exceeds-2500
#19
Sophie Cousins
No abstract text is available yet for this article.
2015: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/26343848/factors-affecting-the-acceptance-of-pandemic-influenza-a-h1n1-vaccine-amongst-essential-service-providers-a-cross-sectional-study
#20
Alice Beattie, Katie Palmer, Emily Rees, Zoe Riddell, Charlotte Roberts, Rachel Jordan
Although mentioned in the UK pandemic plan, essential service providers were not among the priority groups. They may be important targets of future influenza pandemic vaccination campaigns. Therefore, we conducted a cross-sectional survey among 380 employees from West Midlands police headquarters and 15 operational command units in the West Midlands Area during December 2009-February 2010 to identify factors affecting intention to accept the pandemic influenza A (H1N1) vaccine. One hundred and ninety nine (52...
2012: Vaccines
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