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https://www.readbyqxmd.com/read/29784460/review-of-real-time-3-dimensional-image-guided-radiation-therapy-on-standard-equipped-cancer-radiation-therapy-systems-are-we-at-the-tipping-point-for-the-era-of-real-time-radiation-therapy
#1
Paul J Keall, Doan Trang Nguyen, Ricky O'Brien, Pengpeng Zhang, Laura Happersett, Jenny Bertholet, Per R Poulsen
PURPOSE: To review real-time 3-dimensional (3D) image guided radiation therapy (IGRT) on standard-equipped cancer radiation therapy systems, focusing on clinically implemented solutions. METHODS AND MATERIALS: Three groups in 3 continents have clinically implemented novel real-time 3D IGRT solutions on standard-equipped linear accelerators. These technologies encompass kilovoltage, combined megavoltage-kilovoltage, and combined kilovoltage-optical imaging. The cancer sites treated span pelvic and abdominal tumors for which respiratory motion is present...
April 14, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29782609/low-cost-customized-cranioplasty-using-a-3d-digital-printing-model-a-case-report
#2
Abel De La Peña, Javier De La Peña-Brambila, Juan Pérez-De La Torre, Miguel Ochoa, Guillermo J Gallardo
Background: Cranial defects usually occur after trauma, neurosurgical procedures like decompressive craniotomy, tumour resections, infection and congenital defects. The purpose of cranial vault repair is to protect the underlying brain tissue, to reduce any localized pain and patient anxiety, and improve cranial aesthetics. Cranioplasty is a frequent neurosurgical procedure achieved with the aid of cranial prosthesis made from materials such as: titanium, autologous bone, ceramics and polymers...
2018: 3D printing in medicine
https://www.readbyqxmd.com/read/29782518/objective-assessment-of-flap-volume-changes-and-aesthetic-results-after-adjuvant-radiation-therapy-in-patients-undergoing-immediate-autologous-breast-reconstruction
#3
Yujin Myung, Yousung Son, Tae-Hyun Nam, Eunyoung Kang, Eun-Kyu Kim, In Ah Kim, Keun-Yong Eom, Chan Yeong Heo, Jae Hoon Jeong
BACKGROUND: The use of immediate breast reconstruction and adjuvant radiation therapy is increasing in breast cancer patients. This study aimed to analyze the aesthetic outcome and changes in flap volume in patients with breast cancer undergoing radiation therapy of the surgical site after immediate autologous tissue reconstruction. METHODS: Immediate abdominal free flap breast reconstruction following unilateral mastectomy was performed in 42 patients; 21 patients received adjuvant radiation (study group) and 21 patients did not (control group)...
2018: PloS One
https://www.readbyqxmd.com/read/29781768/guided-bone-regeneration-and-implant-placement-in-association-with-a-coronally-positioned-palatal-sliding-flap-a-17-year-follow-up-case-report
#4
Carlo Maiorana, Pier Paolo Poli, Mario Beretta
The aim of the present case report was to show the 17-year hard and soft tissues stability of guided bone regeneration procedure associated with dental implants insertion. A 52-year-old male patient presented with a partial edentulism in the upper right maxilla. A graft consisting of deproteinized bovine bone mineral and autogenous bone stabilized by a non-resorbable expanded polytetrafluoroethylene membrane was used to reconstruct the missing bone applying the biological principles of guided bone regeneration...
May 21, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29779856/kinematic-reconstruction-in-cardiovascular-imaging
#5
G Bastarrika, I J González de la Huebra Rodríguez, M Calvo-Imirizaldu, V M Suárez Vega, A Alonso-Burgos
OBJECTIVE: Advances in clinical applications of computed tomography have been accompanied by improvements in advanced post-processing tools. In addition to multiplanar reconstructions, curved planar reconstructions, maximum intensity projections, and volumetric reconstructions, very recently kinematic reconstruction has been developed. This new technique, based on mathematical models that simulate the propagation of light beams through a volume of data, makes it possible to obtain very realistic three dimensional images...
May 17, 2018: Radiología
https://www.readbyqxmd.com/read/29779423/cognitive-performance-and-locomotor-adaptation-in-persons-with-anterior-cruciate-ligament-reconstruction
#6
Amanda E Stone, Jaimie A Roper, Daniel C Herman, Chris J Hass
BACKGROUND: Persons with anterior cruciate ligament reconstruction (ACLR) show deficits in gait and neuromuscular control following rehabilitation. This altered behavior extends to locomotor adaptation and learning, however the contributing factors to this observed behavior have yet to be investigated. OBJECTIVE: The purpose of this study was to assess differences in locomotor adaptation and learning between ACLR and controls, and identify underlying contributors to motor adaptation in these individuals...
May 1, 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29778016/multiscale-reconstruction-of-a-synthetic-biomimetic-micro-niche-for-enhancing-and-monitoring-the-differentiation-of-stem-cells
#7
Rui Li, Jinming Li, Jianbin Xu, Dexter Siu Hong Wong, Xiaoyu Chen, Weihao Yuan, Liming Bian
Stem cells reside in a three-dimensional (3D) niche microenvironment, which provides specific cues, including cell-matrix interactions and soluble factors, that are essential to the differentiation of stem cells in vivo. Herein we demonstrate a general approach to the synthetic reconstruction of 3D biomimetic niche environment of stem cells by the multiscale combination of macroscopic porous hydrogels and a nanoscale upconversion nanoparticles (UCNP)-based nanocomplex. The porous biopolymeric hydrogels emulate the spongy bone microstructure and provide 3D environment conducive to the differentiation of seeded stem cells...
May 4, 2018: Biomaterials
https://www.readbyqxmd.com/read/29777859/three-dimensional-model-of-the-female-perineum-and-pelvic-floor-muscles
#8
Géraldine Giraudet, Laurent Patrouix, Christian Fontaine, Xavier Demondion, Michel Cosson, Chrystèle Rubod
OBJECTIVE: The anatomy of the perineum and the pelvic diaphragm of woman is complex. A numerical complete three-dimensional (3D) model of every muscle of the woman pelvis doesn't exist. The pathophysiology of genital prolapse is still debated. Knowledge of anatomy is essential to better understand its mechanisms. The aim of this research was to build a complete three-dimensional model of the female perineum and pelvic floor muscles. STUDY DESIGN: To model the pelvic muscles we reconstructed them in three dimensions from tracing a magnetic resonance imaging (MRI) of a female pelvis from a cadaver...
May 16, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29776156/realizations-of-highly-heterogeneous-collagen-networks-via-stochastic-reconstruction-for-micromechanical-analysis-of-tumor-cell-invasion
#9
Hanqing Nan, Long Liang, Guo Chen, Liyu Liu, Ruchuan Liu, Yang Jiao
Three-dimensional (3D) collective cell migration in a collagen-based extracellular matrix (ECM) is among one of the most significant topics in developmental biology, cancer progression, tissue regeneration, and immune response. Recent studies have suggested that collagen-fiber mediated force transmission in cellularized ECM plays an important role in stress homeostasis and regulation of collective cellular behaviors. Motivated by the recent in vitro observation that oriented collagen can significantly enhance the penetration of migrating breast cancer cells into dense Matrigel which mimics the intravasation process in vivo [Han et al...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775115/immunofluorescent-localization-of-non-myelinating-schwann-cells-and-their-interactions-with-immune-cells-in-mouse-thymus
#10
Dailun Hu, Philip K Nicholls, Changfu Yin, Khama Kelman, Qionglan Yuan, Wayne K Greene, Zhongli Shi, Bin Ma
The thymus is innervated by sympathetic/parasympathetic nerve fibers from the peripheral nervous system (PNS), suggesting a neural regulation of thymic function including T-cell development. Despite some published studies, data on the innervation and nerve-immune interaction inside the thymus remain limited. In the present study, we used immunofluorescent staining of glial fibrillary acidic protein (GFAP) coupled with confocal microscopy/three-dimensional (3D) reconstruction to reveal the distribution of non-myelinating Schwann cells (NMSC) and their interactions with immune cells inside mouse thymus...
May 1, 2018: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
https://www.readbyqxmd.com/read/29775014/-the-application-of-3d-reconstruction-in-investigating-the-frontal-sinus-drainage-pathway-based-on-computer-tomography-data
#11
Y Liu, X Q Ma, X H Sun, S Dai, J F Zhang, H B Li, X Ma, J Y Wang, Q Dou, J Y Tian, J P Jia
Objective: The aim of this study is to explore the value of 3D reconstruction technology based on computer tomography data in understanding the frontal sinus drainage pathway. Method: Three-dimensional reconstruction of DICOM data from 100 cases of sinus CT was performed by using Mimics 19.0 software. The 3D models were used to study types, the relative locations of frontal sinus and recess cells as well as the influence of the frontal sinus drainage pathway. Result: The 3D model of frontal sinus, frontal recess cells and frontal sinus drainage pathway were reconstructed successfully...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29774634/study-of-hyperpigmentation-in-human-skin-disorder-using-different-electron-microscopy-techniques
#12
Seulgi Noh, Hyosun Choi, Ji Soo Kim, Il-Hwan Kim, Ji Young Mun
There is a global trend of increase in the demand for three-dimensional electron microscopy with high resolution. The ultrastructural change and related functional studies are necessary to investigate biological phenomena. In this study, currently available 3D reconstruction techniques of electron microscopes (serial block-face scanning electron microscopy and focused ion beam-scanning electron microscopy) were used to investigate hyperpigmentary disorders in human skin. In the basal layer of the epidermis in the human skin, there are melanocytes that produce melanin and keratinocytes that act as a barrier against environmental damage...
May 18, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29772676/three-dimensional-terahertz-coded-aperture-imaging-based-on-geometric-measures
#13
Shuo Chen, Xiaoqiang Hua, Hongqiang Wang, Chenggao Luo, Yongqiang Cheng, Bin Deng
For synthetic aperture radars, it is difficult to achieve forward-looking and staring imaging with high resolution. Fortunately, terahertz coded-aperture imaging (TCAI), an advanced radar imaging technology, can solve this problem by producing various irradiation patterns with coded apertures. However, three-dimensional (3D) TCAI has two problems, including a heavy computational burden caused by a large-scale reference signal matrix, and poor resolving ability at low signal-to-noise ratios (SNRs). This paper proposes a 3D imaging method based on geometric measures (GMs), which can reduce the computational burden and achieve high-resolution imaging for low SNR targets...
May 16, 2018: Sensors
https://www.readbyqxmd.com/read/29771086/-design-of-cross-sectional-anatomical-model-focused-on-drainage-pathways-of-paranasal-sinuses
#14
Y Zha, W Lv, Y L Gao, Z Z Zhu, Z Q Gao
Objective: To design and produce cross-sectional anatomical models of paranasal sinuses for the purpose of demonstrating drainage pathways of each nasal sinus for the young doctors. Method: We reconstructed the three-dimensional model of sinuses area based on CT scan data, and divided it into 5 thick cross-sectional anatomy models by 4 coronal plane,which cross middle points of agger nasi cell, ethmoid bulla, posterior ethmoid sinuses and sphenoid sinus respectively. Then a 3D printerwas used to make anatomical cross-sectional anatomical models...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29771036/-3d-computed-tomographic-study-of-concha-bullosa-drainage-pathway
#15
W H Zhang, Y L Zhao, X D Li
Objective: The aim of this study is to study the related structures with concha bullosa drainage passway in inpatients with concha bullosa disease. Method: A total of 90 patients with peritubular middle turbinate (144 sides) were examined by 16-slice spiral CT. The distribution of the middle turbinate and the distribution of the drainage channel were analyzed by three-dimensional reconstruction technique and image workstation software. Result: The distribution of the morphology and drainage channel of 144 concha bullosa have statistically significant ( P <0...
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29770766/histogram-pattern-analysis-of-the-lung-perfused-blood-volume-for-assessment-of-pulmonary-thromboembolism
#16
Munemasa Okada, Takafumi Nomura, Yoshiteru Nakashima, Yoshie Kunihiro, Shoji Kido
PURPOSE: We aimed to evaluate the usefulness of histograms of lung perfused blood volume (HLPBV) based on the presence of pulmonary thromboembolism (PTE) and the pulmonary embolic burden. METHODS: A total of 168 patients (55 males; mean age, 62.9 years) underwent contrast-enhanced dual-energy computed tomography (DECT) between January 1 2012 and October 31 2014. Initial DECT images were three-dimensionally reconstructed, and the HLPBV patterns were divided into three types, including the symmetric type (131 patients, 78...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29765420/a-feasible-method-of-angiogenesis-assessment-in-gastric-cancer-using-3d-microvessel-density
#17
Lu Zhang, Fei Zheng, Zhigang Peng, Zijing Hu, Zhi Yang
Background: Cancer stem cell (CSC) promotes angiogenesis which plays an important role in tumor occurrence, growth, and metastasis. Accurately, quantifying the tumor vasculature can help understanding CSC characteristics and improve cancer diagnosis, therapy planning, and evaluation. The objective of this study is to present a method for improved angiogenesis assessment. Methods: We proposed a three-dimensional microvessel density (3D MVD) to evaluate tumor angiogenesis and tested it in animal models...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29765308/diverse-long-range-axonal-projections-of-excitatory-layer-2-3-neurons-in-mouse-barrel-cortex
#18
Takayuki Yamashita, Angeliki Vavladeli, Aurélie Pala, Katia Galan, Sylvain Crochet, Sara S A Petersen, Carl C H Petersen
Excitatory projection neurons of the neocortex are thought to play important roles in perceptual and cognitive functions of the brain by directly connecting diverse cortical and subcortical areas. However, many aspects of the anatomical organization of these inter-areal connections are unknown. Here, we studied long-range axonal projections of excitatory layer 2/3 neurons with cell bodies located in mouse primary somatosensory barrel cortex (wS1). As a population, these neurons densely projected to secondary whisker somatosensory cortex (wS2) and primary/secondary whisker motor cortex (wM1/2), with additional axon in the dysgranular zone surrounding the barrel field, perirhinal temporal association cortex and striatum...
2018: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29765272/approach-to-reconstruction-of-cheek-defects
#19
REVIEW
Berkay Başağaoğlu, Mohin Bhadkamkar, Pierce Hollier, Edward Reece
The cheek is the largest facial unit with a prominent position on the face. Trauma, burns, and the resection of skin cancers constitute common sources of injury, potentially resulting in defects that, through natural healing, produce noticeable scarring. Surgical repair focuses on the reformation of three-dimensional geometries, proper establishment of symmetry, and the minimization of color and texture discrepancies to the surrounding. Defects located in this region may extend to the orbital, nasal, or buccal units and cause unique structural and functional disturbances...
May 2018: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29765271/approach-to-reconstruction-of-nasal-defects
#20
REVIEW
Berkay Başağaoğlu, Kausar Ali, Pierce Hollier, Renata S Maricevich
The nose is the most central and anterior projecting facial feature. Therefore, the presence of a defect is easily noticeable to the untrained eye. Return of the defect to the original form is an achievable end goal of reconstruction, necessitating appropriate reformation of three-dimensional geometry, proper establishment of symmetry, and excellent color and texture match to the adjacent structures. Regarding its physiological importance, disruption of the normal function may cause respiratory obstruction and contribute to patient distress...
May 2018: Seminars in Plastic Surgery
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