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https://www.readbyqxmd.com/read/29776936/ethambutol-and-isoniazid-induced-severe-neurotoxicity-in-a-patient-undergoing-continuous-ambulatory-peritoneal-dialysis
#1
Meijun Si, Huiqun Li, Yanru Chen, Hui Peng
Ethambutol (EMB) and isoniazid (INH) are the first-line antituberculosis (anti-TB) drugs. However, their neurotoxicity could cause adverse effect and the patients with end-stage renal disease are especially vulnerable due to the reduction in renal drug clearance. Here, we report a 36-year-old man receiving peritoneal dialysis developed progressive paralysis in lower extremities, vision loss and hoarseness 4 months after anti-TB treatment with INH, EMB and rifapentine because of concomitant pulmonary tuberculosis...
May 18, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29772050/combined-femtosecond-laser-assisted-cataract-surgery-and-small-gauge-pars-plana-vitrectomy-using-different-devices-a-new-trend-for-vitreoretinal-surgery
#2
Bruno de Queiroz Alves, Oswaldo Ferreira Moura Brasil, Cristiano Toesca Espinhosa, Ricardo Miguel Japiassu, Mariana Batista Gonçalves, Otaviano Magalhães Júnior, André Maia, Emmerson Badaró, Paula Serraino, Arturo Alezzandrinni, Mauricio Maia
BACKGROUND AND OBJECTIVE: To report the efficacy, safety, and benefits of femtosecond laser-assisted cataract surgery (FLACS) combined with sutureless 23-gauge pars plana vitrectomy (PPV). PATIENTS AND METHODS: This multicenter, retrospective study evaluated patient records and videos of 43 cases with retinal pathologies and cataract who underwent the combined procedure. RESULTS: In 44.2% and 55.8% of cases, respectively, the LenSx Laser (femtosecond machine; Alcon, Fort Worth, TX) and the Constellation (vitreous cutter; Alcon, Fort Worth, TX), and the Victus (femtosecond machine; Bausch + Lomb, Rochester, NY) and Stellaris PC (vitreous cutter; Bausch + Lomb, Rochester, NY) were used...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29765868/retrobulbar-steatitis-and-meningitis-empyema-secondary-to-right-otitis-media-right-otitis-interna-and-an-inflammatory-polyp-in-a-cat
#3
Elena Fenollosa-Romero, Olivier Taeymans, Pieter Nelissen, Giunio B Cherubini, Claudia Busse
The purpose was to describe a case of retrobulbar steatitis and meningitis in a cat caused by otitis media, otitis interna and an inflammatory polyp in the middle ear. Investigations included ophthalmic and neurological examinations, haematology and biochemistry, magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis and aerobic, anaerobic bacterial and fungal culture of material from the middle ear. A 6-year-old female neutered domestic-short-haired cat presented with right-sided exophthalmos and resistance to retropulsion...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29762893/retrobulbar-vs-peribulbar-regional-anesthesia-techniques-using-bupivacaine-in-dogs
#4
Yael Shilo-Benjamini, Peter J Pascoe, David J Maggs, Steven R Hollingsworth, Ann R Strom, Kathryn L Good, Sara M Thomasy, Philip H Kass, Erik R Wisner
OBJECTIVE: To compare the effectiveness of retrobulbar anesthesia (RBA) and peribulbar anesthesia (PBA) in dogs. ANIMAL STUDIED: Six adult mixed-breed dogs (18-24 kg). PROCEDURES: In a randomized, masked, crossover trial with a 10-day washout period, each dog was sedated with intravenously administered dexmedetomidine and administered 0.5% bupivacaine:iopamidol (4:1) as RBA (2 mL via a ventrolateral site) or PBA (5 mL divided equally between ventrolateral and dorsomedial sites)...
May 15, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29756077/persistent-macular-puckering-following-excision-of-causative-orbital-tumor
#5
Curtis J Heisel, David N Zacks, Alon Kahana
Purpose: To describe the clinical course of a patient with a retrobulbar orbital tumor causing myopic shift and macular pucker. Observation: Following complete surgical removal of a retrobulbar orbital cavernous hemangioma, the myopic shift improved but the macular pucker persisted even 3 years after orbital surgery, with no sign of tumor recurrence. Conclusion and importance: Chorioretinal folds secondary to chronic mechanical force from an orbital tumor may persist long after the tumor is removed...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29702978/optic-neuropathy-causing-vertical-unilateral-hemianopsia-after-pars-plana-vitrectomy-for-a-macular-hole-a-case-report
#6
Hirohiko Kawashima, Norihiro Nagai, Hajime Shinoda, Kazuo Tsubota, Yoko Ozawa
INTRODUCTION: Recent progress in medical technology has resulted in improved surgical outcomes of pars plana vitrectomy (PPV); with microincision systems, the incidence of procedure-related complications during surgery has been reduced. However, unpredictable visual field defects after PPV remain an unresolved issue. A few reports have shown that damage to the retinal neurofibers owing to dry-up during air/fluid exchange or retinal neurotoxicity of the dye used to visualize the internal limiting membrane (ILM), as well as unintentional removal of retinal neurofibers during ILM peeling, are responsible for such visual field disorders...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29699980/neuro-ophthalmological-manifestations-of-beh%C3%A3-et-s-disease
#7
Ammr Alghamdi, Bahram Bodaghi, Chloé Comarmond, Anne Claire Desbois, Fanny Domont, Bertrand Wechsler, Raphael Depaz, Phuc Le Hoang, Patrice Cacoub, Valérie Touitou, David Saadoun
BACKGROUND: The neuro-ophthalmological manifestations of Behcet's disease (BD) are rare, and data regarding their characteristics and outcome are lacking. OBJECTIVE: To report prevalence, main characteristics and outcome of neuro-ophthalmological manifestations in BD. PATIENTS AND METHODS: This is a retrospective monocentric study of 217 patients diagnosed with neuro-Behçet's disease (NBD), of whom 29 (13.3%) patients presented with neuro-ophthalmological manifestations (55% of men and mean±SD age of 26±8 years)...
April 26, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29623721/evaluation-of-ocular-perforation-during-retrobulbar-block-using-high-resolution-spectral-domain-optical-coherence-tomography-and-optical-coherence-tomography-angiography
#8
Stanislao Rizzo, Ruggero Tartaro, Lucia Finocchio, Andrea Giorni, Daniela Bacherini, Alfonso Savastano
INTRODUCTION: This article reports a case of ocular perforation during a retrobulbar block in a patient who underwent scleral buckle for retinal detachment. METHODS: Sterile air was immediately injected into the vitreous cavity to restore intraocular pressure and the scleral buckle operation was quickly finished. One week later, a laser retinopexy was performed on the two retinal holes that were outside the foveal area. After 6 months, spectral domain-optical coherence tomography and optical coherence tomography angiography were performed on the perforated wall centered on the exit hole area...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29606723/retrobulbar-malignant-peripheral-nerve-sheath-tumor-in-a-golden-retriever-dog-a-challenging-diagnosis
#9
Cécile Briffod, Pierre Hélie, Julie De Lasalle, Louis-Philippe de Lorimier, Alicia R Moreau, Derron A Alves, Maria Vanore
A 9-year-old golden retriever dog was diagnosed with a left retrobulbar mass. Fine-needle aspirations and incisional biopsies resulted in discordant diagnoses: myxosarcoma/myxoma or rhadomyosarcoma, respectively. Immunohistochemistry following exenteration allowed definitive diagnosis of malignant peripheral nerve sheath tumor with fibromyxomatous differentiation. Fifteen weeks after surgery, an aggressive recurrence resulted in euthanasia.
April 2018: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/29594838/the-relation-between-retrobulbar-blood-flow-and-posterior-ocular-changes-measured-using-spectral-domain-optical-coherence-tomography-in-patients-with-obstructive-sleep-apnea-syndrome
#10
Hüseyin Fındık, Metin Çeliker, Mehmet Gökhan Aslan, Fatma Beyazal Çeliker, Mehmet Fatih İnecikli, Engin Dursun, Murat Okutucu, Ünal Şahin
PURPOSE: To investigate the effect of posterior ocular hemodynamics on the retinal nerve fiber layer (RNFL), choroid thickness (CT) and central macular thickness (CMT) in patients with obstructive sleep apnea syndrome (OSAS) and to reveal the association with glaucomatous optic neuropathy. METHODS: The research was planned as a prospective, randomized study. The ophthalmic, retinal and posterior ciliary artery pulsatile index (PI) and resistive index (RI) were measured by colored Doppler sonography...
March 29, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29594157/use-of-nasotracheal-intubation-during-general-anesthesia-in-two-ponies-with-tracheal-collapse
#11
Keila K Ida, Aurélie Sauvage, Alexandra Gougnard, Magda Grauwels, Didier Serteyn, Charlotte Sandersen
Ponies with tracheal collapse may have an increased anesthetic risk due to airway obstruction during induction and recovery. To our knowledge, there are no anesthetic descriptions of these patients, despite a reported 5.6% incidence and 77% mortality rate. Two Shetland ponies with tracheal collapse, a 12-year-old male (pony 1) and a 27-year-old female (pony 2), were referred for right eye enucleation due to a perforating corneal ulcer and severe recurrent uveitis, respectively. Pony 1 was stressed, had lung stridor and hyperthermia, and developed inspiratory dyspnea with handling...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29563957/multicentric-glioblastoma-multiforme-mimicking-optic-neuritis
#12
Francesco Pellegrini, Andrew G Lee, Cristina Cercato
A 49-year-old previously healthy woman presented with acute painless visual loss in the right eye, a right relative afferent pupillary defect, and a normal fundus examination. She was diagnosed with retrobulbar "optic neuritis" and given a course of intravenous steroids. Despite treatment, however, she continued to lose vision and serial visual field testing confirmed a junctional scotoma in the fellow eye. Cranial magnetic resonance imaging (MRI) showed a mass at the junction between the right optic nerve and the anterior aspect of the chiasm and a right frontal lesion that proved to be multicentric glioblastoma multiforme...
April 2018: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29551422/incidence-risk-factors-and-management-of-blindness-after-orbital-surgery
#13
Sarah M Jacobs, Colin P McInnis, Matthew Kapeles, Shu-Hong Chang
PURPOSE: Severe vision loss is a risk of orbital surgery which physicians should counsel patients about, but the overall risk rate is unknown. This research was conducted to determine the risk of severe vision loss related to orbital surgery. DESIGN: Retrospective review. PARTICIPANTS: Patients who underwent orbital surgery at either of 2 academic medical centers between January 1994 and December 2014. METHODS: A billing database search was conducted to identify all patients who had orbital surgery during the study period, cross-checked against diagnostic codes related to vision loss...
March 15, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29546060/acute-effect-of-hypervolemic-hemodilution-on-retrobulbar-hemodynamics-in-anterior-ischemic-optic-neuropathy
#14
Marion Bienert, Niklas Plange, Andreas Remky, Kay Oliver Arend, David Kuerten
Purpose: Ischemic ocular disorders may be treated by hypervolemic hemodilution. The presumed therapeutic benefit is based on a volume effect and improved rheological factors. The aim was to investigate the acute effect of intravenous hydroxyethyl starch on retrobulbar hemodynamics in patients with nonarteritic anterior ischemic optic neuropathy (NAION). Methods: 24 patients with acute NAION were included. Retrobulbar hemodynamics were measured using color Doppler imaging before and 15 min after intravenous infusion of 250 cc 10% hydroxyethyl starch (HES)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29532640/impaired-cerebrospinal-fluid-dynamics-along-the-entire-optic-nerve-in-normal-tension-glaucoma
#15
Achmed Pircher, Margherita Montali, Peter Wostyn, Joachim Pircher, Jatta Berberat, Luca Remonda, Hanspeter E Killer
PURPOSE: To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS: Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic criteria of NTG and underwent CT-cisternography. Twelve subjects without NTG (24 eyes) served as controls. Contrast-loaded cerebrospinal fluid (CLCSF) density measurements in Hounsfield units (HU) were performed at four defined regions along the ON and in the basal cistern...
March 12, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29526320/optic-neuritis-in-paediatric-patients-experience-over-27-years-and-a-management-protocol
#16
L Monge Galindo, A L Martínez de Morentín, V Pueyo Royo, J P García Iñiguez, S Sánchez Marco, J López-Pisón, J L Peña-Segura
INTRODUCTION AND OBJECTIVE: In this article, we present our experience on optic neuritis (ON) and provide a diagnostic/therapeutic protocol, intended to rule out other aetiologies (particularly infection), and a fact sheet for parents. MATERIAL AND METHODS: We conducted a descriptive, retrospective study of patients with ON over a 27-year period (1990-2017). A review of the available scientific evidence was performed in order to draft the protocol and fact sheet...
March 8, 2018: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/29521438/contrast-enhanced-ultrasonography-for-evaluation-of-blood-perfusion-in-normal-canine-eyes
#17
Sunghwa Hong, Seungjo Park, Dahae Lee, Ahyoung Cha, Dongeun Kim, Jihye Choi
OBJECTIVE: This study was performed to evaluate ocular structures using contrast-enhanced ultrasonography (CEUS) in dogs to assess the feasibility of CEUS for investigating the blood perfusion of canine eyes. ANIMAL STUDIED: Eight purpose-bred beagles were used. PROCEDURES: Blood perfusion and vascularity of the right eye were evaluated using color Doppler, power Doppler, and CEUS with Sonazoid® . Vascular changes were quantitatively evaluated by measuring peak intensity, time to initial upslope, and time to peak from the ciliary body, iris, choroid, retina, and the retrobulbar region by CEUS...
March 9, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29517498/commentary-on-restoration-of-visual-loss-with-retrobulbar-hyaluronidase-injection-after-hyaluronic-acid-filler
#18
COMMENT
Steven Fagien, Jean Carruthers
No abstract text is available yet for this article.
March 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29507012/sle-presenting-as-demyelinative-autoimmune-visual-loss
#19
Ami Schattner, Shilo Voichanski, Livnat Uliel
A healthy 38-year-old woman developed sudden unilateral vision loss due to retrobulbar optic neuritis in the wake of varicella-zoster virus infection. She had no further central nervous system (CNS) lesions. Antinuclear antibodies (ANA) and anti-aquaporin 4 antibodies were found, consistent with neuromyelitis optica (NMO). Later, serial MRIs showed dynamic short-segment and long-segment myelitis lesions, ANA titre increased and additional autoantibodies were found including anti-dsDNA, anti-chromatin/nucleosome and antiphospholipid antibodies...
March 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29506873/retrobulbar-abscess-rare-complication-after-repair-of-an-oroantral-communication
#20
H Mahmood, H Flora, C Murphy, D Sutton
We present the case of a retrobulbar abscess that developed secondary to the repair of an oroantral communication. Orbital abscesses have been described in relation to odontogenic infections, facial injury, sinusitis, and after dental extractions but, to the best of our knowledge, none has been reported in these circumstances. Retrobulbar abscess is a rare complication, but early clinical and radiological diagnosis, and urgent decompression are vital because it comes with considerable risk of irreversible visual impairment...
April 2018: British Journal of Oral & Maxillofacial Surgery
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