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https://www.readbyqxmd.com/read/27933376/percutaneous-biopsy-of-retrobulbar-masses-anatomical-considerations-and-mri-guidance
#1
Faramarz Edalat, Roberto Luigi Cazzato, Julien Garnon, Georgia Tsoumakidou, Gerlinde Avérous, Jean Caudrelier, Guillaume Koch, Afshin Gangi
PURPOSE: Obtaining adequate tissue from retrobulbar masses remains a challenge. To this end, a new method of retrobulbar mass biopsy using MRI guidance is presented. MATERIALS AND METHODS: Two patients (7- and 71-year-old male) with indeterminate retrobulbar masses underwent bioptic and cytological samplings using MR-compatible 18G and 20-22G needles, and multi-planar MR fluoroscopy. An inferior approach was taken to avoid injury to the optic nerve and ophthalmic arteries...
December 8, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27930785/metallic-foreign-body-trapped-within-the-retrobulbar-part-of-the-optic-nerve
#2
Reema Bansal, Pallavi Singh, Sandeep Bansal
No abstract text is available yet for this article.
December 8, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27906852/fenestration-of-solid-orbital-implants-reducing-retrobulbar-hematoma-rate
#3
Scott J Farber, Jenny L Yu, Dennis C Nguyen, Albert S Woo
PURPOSE: Retrobulbar hematoma is an uncommon but potentially devastating complication following repair of orbital fractures. Since 2007, the senior author routinely fenestrates the solid porous polyethylene implants commonly used for orbital reconstruction. The perforated implant may facilitate drainage of postoperative bleeding and may potentially reduce the risk of retrobulbar hematoma. This study examines the rates of retrobulbar hematoma in patients who underwent orbital fracture reconstruction with placement of fenestrated or nonfenestrated implants...
November 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27904503/stem-cell-ophthalmology-treatment-study-scots-bone-marrow-derived-stem-cells-in-the-treatment-of-leber-s-hereditary-optic-neuropathy
#4
Jeffrey N Weiss, Steven Levy, Susan C Benes
The Stem Cell Ophthalmology Treatment Study (SCOTS) is currently the largest-scale stem cell ophthalmology trial registered at ClinicalTrials.gov (identifier: NCT01920867). SCOTS utilizes autologous bone marrow-derived stem cells (BMSCs) to treat optic nerve and retinal diseases. Treatment approaches include a combination of retrobulbar, subtenon, intravitreal, intra-optic nerve, subretinal, and intravenous injection of autologous BMSCs according to the nature of the disease, the degree of visual loss, and any risk factors related to the treatments...
October 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27893548/pressureless-orbital-decompression-for-myopic-proptosis
#5
Saul N Rajak, Richard A McGovern, Dinesh Selva
Orbital decompression surgery increases the orbital volume. It has rarely been used for proptosis of the large highly myopic globe. However, external decompression surgery carries significant risks because of the large thin-walled globe. The authors report the first use of endoscopic medial wall orbital decompression surgery in this setting to obviate the risk of globe pressure.Endoscopic medial wall decompression brought about a 4 mm reduction of proptosis, correction of exotropia and elimination of retrobulbar ache providing good symmetry with the fellow eye...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27889503/gamma-knife-radiosurgery-for-uveal-metastases-report-of-three-cases-and-a-review-of-the-literature
#6
William J Ares, Daniel Tonetti, Jenny Y Yu, Edward A Monaco, John C Flickinger, L Dade Lunsford
PURPOSE: Uveal metastases are ophthalmologic tumors that have historically been treated by fractionated external beam radiation therapy or invasive brachytherapy. The need for rapid response and less invasive management options led the authors to explore the use of Gamma knife stereotactic radiosurgery (SRS) for this common problem. DESIGN: Interventional case series. METHODS: Intervention: In order to prevent eye movement during the procedure, all three patients underwent a retrobulbar anesthetic block followed by magnetic resonance imaging to detect the target...
November 23, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27882744/transpalpebral-exenteration-in-cattle-a-retrospective-study-of-115-cases
#7
Munashe Chigerwe, John A Angelos, Lisa Gamsjäeger, Meera C Heller
OBJECTIVE: To describe the indications for exenteration and complications associated with the procedure. ANIMALS STUDIED: 115 cattle. PROCEDURES: Medical records of cattle presented for unilateral exenteration evaluated at the University of California, Davis Veterinary Medical Teaching Hospital from January 1985 through December 2015 were reviewed. RESULTS: Median (range) age at presentation for all cattle was 6 (0.2-30) years...
November 24, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27875090/clinical-computed-tomographic-magnetic-resonance-imaging-and-histologic-findings-associated-with-myxomatous-neoplasia-of-the-temporomandibular-joint-in-two-dogs
#8
Arana Parslow, David P Taylor, David J Simpson
CASE DESCRIPTION A 15-year-old neutered female mixed-breed dog (dog 1) and an 11-year-old neutered female Labrador Retriever (dog 2) were examined because of unilateral exophthalmus, third eyelid protrusion, and periorbital swelling that failed to respond to antimicrobial treatment. CLINICAL FINDINGS Both dogs underwent ultrasonographic, CT, and MRI examination of the head. In both dogs, advanced imaging revealed a poorly defined, peripherally contrast-enhancing, mucous-filled cystic mass that radiated from the temporomandibular joint and infiltrated the periorbital tissues and retrobulbar space...
December 1, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/27860232/the-proteomes-of-the-human-eye-a-highly-compartmentalized-organ
#9
Gilbert S Omenn
Proteomics has now published a series of Dataset Briefs on the EyeOme from the HUPO Human Proteome Project with high-quality analyses of the proteomes of these compartments of the human eye: retina, iris, ciliary body, retinal pigment epithelium/choroid, retrobulbar optic nerve, and sclera, with 3436, 2929, 2867, 2755, 2711, and 1945 proteins, respectively. These proteomics resources represent a useful starting point for a broad range of research aimed at developing preventive and therapeutic interventions for the various causes of blindness...
November 9, 2016: Proteomics
https://www.readbyqxmd.com/read/27857868/surgical-anatomy-of-the-medial-wall-of-the-orbit-in-14-human-cadavers
#10
Juan R Gras-Cabrerizo, Maria Martel-Martin, Jacinto Garcia-Lorenzo, Fernando Rodríguez-Álvarez, Joan R Montserrat-Gili, Rosa Mirapeix-Lucas, Humbert Massegur-Solench
Objective The aim of our study is to present the anatomical landmarks to perform an endoscopic endonasal approach to the medial wall of the orbit (EEAMO). Material and Methods We performed 14 complete nasal and orbital endoscopic dissections in 7 adult cadaveric heads. Results The EEAMO provides a surgical corridor between the medial rectus muscle superiorly and the inferior rectus muscle inferiorly .The mean distance between the ethmoidal crest and medial rectus muscle was 1.5 cm (range, 1.3-1.9 cm)...
December 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27857759/stem-cell-ophthalmology-treatment-study-scots-improvement-in-serpiginous-choroidopathy-following-autologous-bone-marrow-derived-stem-cell-treatment
#11
Jeffrey N Weiss, Susan C Benes, Steven Levy
We report results in a 77-year-old male patient with visual loss from long-standing serpiginous choroidopathy treated with bone marrow derived stem cells (BMSC) within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical trial and the largest ophthalmology stem cell study registered at the National Institutes of Health to date (ClinicalTrials.gov Identifier: NCT01920867). Eight months after treatment by a combination of retrobulbar, subtenon, intravitreal and intravenous injection of BMSC, the patient's best corrected Snellen acuity improved from 20/80(-) to 20/60(+1) in the right eye and from 20/50(-) to 20/20(-3) in the left eye...
September 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27833708/surgical-treatment-of-orbital-blowout-fractures-complications-and-postoperative-care-patterns
#12
Matthew Shew, Michael P Carlisle, Guanning Nina Lu, Clinton Humphrey, J David Kriet
Orbital fractures are a common result of facial trauma. Sequelae and indications for repair include enophthalmos and/or diplopia from extraocular muscle entrapment. Alloplastic implant placement with careful release of periorbital fat and extraocular muscles can effectively restore extraocular movements, orbital integrity, and anatomic volume. However, rare but devastating complications such as retrobulbar hematoma (RBH) can occur after repair, which pose a risk of permanent vision loss if not addressed emergently...
November 2016: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/27832280/imaging-of-ocular-perforation-after-retrobulbar-block
#13
Stanislao Rizzo, Andrea Giorni, Alfonso Savastano
No abstract text is available yet for this article.
November 10, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27827444/associated-factors-for-visibility-and-width-of-retrobulbar-subarachnoid-space-on-swept-source-optical-coherence-tomography-in-high-myopia
#14
Hua Fan, Hongjie Ma, Rulong Gao, Danny Siu-Chun Ng, Carol Y Cheung, Shuangnong Li, Dezheng Wu, Shibo Tang
Subarachnoid space (SAS) around optic nerve can be visible with swept-source optical coherence tomography (SS-OCT). However, the relevant factors for its visibility and width have not been reported. In this prospective study, 193 eyes with high myopia were evaluated by SS-OCT. The relationship between age, gender, axial length, optic disc area, parapapillary atrophy (PPA) area, peripapillary choroidal thickness with the visibility and width of SAS were assessed. The results showed that SAS was observed in 125 (64...
November 9, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27814327/retrobulbar-injections-for-blind-painful-eyes-a-comparative-study-of-retrobulbar-alcohol-versus-chlorpromazine
#15
Alicia Galindo-Ferreiro, Patricia Akaishi, Augusto Cruz, Rajiv Khandekar, Saif Al Dosairi, Mohammed Dufaileej, Ahmed Al Salem, Alberto Galvez-Ruiz, E Randy Craven
PURPOSE: The purpose of the study was to evaluate 2 agents used during retrobular injections to relieve pain in blind eyes. METHODS: This masked prospective randomized study compared retrobulbar injections for blind painful eyes that were divided into 2 groups: eyes in group 1 (G-I) received 1.5 mL of absolute alcohol (ethanol) and those in group 2 (G-II) received 1.5 mL of chlorpromazine (25 mg/mL). The pain was graded before, during, and after intervention using a verbal numeric visual analog scale...
November 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27792048/primary-gliosarcoma-of-the-optic-nerve-a-unique-adult-optic-pathway-glioma
#16
Patrick J Cimino, Yevgeniy V Sychev, Luis F Gonzalez-Cuyar, Raghu C Mudumbai, C Dirk Keene
A 90-year-old woman presented with 1-year history of right-sided progressive proptosis, neovascular glaucoma, blindness, and worsening ocular pain. No funduscopic examination was possible because of a corneal opacity. Head CT scan without contrast demonstrated a heterogeneous 4.1 cm (anterior-posterior) by 1.7 cm (transverse) cylindrical mass arising in the right optic nerve and extending from the retrobulbar globe to the optic canal. She underwent palliative enucleation with subtotal resection of the orbital optic nerve and tumor...
October 11, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27780182/the-spectrum-of-amalric-triangular-choroidal-infarction
#17
Julia Nemiroff, Nopasak Phasukkijwatana, Veronika Vaclavik, Aaron Nagiel, Eric R Holz, David Sarraf
PURPOSE: To describe the multimodal imaging findings, including optical coherence tomography angiography analysis, and spectrum of etiologies associated with Amalric triangular choroidal infarction. METHODS: This study is a multicenter, retrospective, observational case series review of the clinical and multimodal imaging findings for six patients with Amalric triangular choroidal infarction. RESULTS: Six patients (10 eyes) with Amalric triangular choroidal infarction were enrolled...
October 11, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27768975/anti-angiogenesis-through-noninvasive-to-minimally-invasive-intraocular-delivery-of-the-peptide-cc12-identified-by-in%C3%A2-vivo-directed-evolution
#18
Chong Chen, Kun Liu, Yupeng Xu, Pengwei Zhang, Yan Suo, Yi Lu, Wenyuan Zhang, Li Su, Qing Gu, Huamao Wang, Jianren Gu, Zonghai Li, Xun Xu
Anti-vascular endothelial growth factor (VEGF) therapies are widely used for the treatment of neovascular fundus diseases such as diabetic retinopathy. However, these agents need to be injected intravitreally, because their strong hydrophilicity and high molecular weight prevent them from penetrating cell membranes and complex tissue barriers. Moreover, the repeated injections that are required can cause infection and tissue injury. In this study, we used in vivo-directed evolution phage display technology to identify a novel dodecapeptide, named CC12, with the ability to penetrate the ocular barrier in a noninvasive (via conjunctival sac instillation) or minimally invasive (via retrobulbar injection) manner...
September 30, 2016: Biomaterials
https://www.readbyqxmd.com/read/27768646/a-case-of-a-spontaneous-self-resolving-retrobulbar-hemorrhage-following-3-4-methylenedioxy-methamphetamine-use
#19
Jordan V Chervenkoff, Saul N Rajak, Dinesh Selva, Garry Davis
This case report discusses the case of a 23-year-old male patient who experienced retrobulbar pain, diplopia, proptosis, and mild lower eyelid bruising after consuming 3,4-methylenedioxy-methamphetamine. The symptoms settled over 10 days and vision returned to normal without intervention. The authors discuss the differential diagnosis relevant to the presenting complaints and propose several mechanisms linking 3,4-methylenedioxy-methamphetamine use to spontaneous nontraumatic intraorbital hematoma.
October 20, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27768642/retrobulbar-injection-of-amphotericin-b-for-orbital-mucormycosis
#20
Kristin E Hirabayashi, Evan Kalin-Hajdu, Frank L Brodie, Robert C Kersten, Matthew S Russell, M Reza Vagefi
A 68-year-old immunocompromised man with rhino-orbital-cerebral mucormycosis was treated with retrobulbar injections of amphotericin B deoxycholate in conjunction with intravenous antifungals and endoscopic sinus debridement. Transient episodes of orbital inflammation were noted after retrobulbar injections, but progression of orbital infection was halted and visual acuity restored with eventual hospital discharge. To the authors' knowledge, clearance of orbital mucormycosis with retrobulbar amphotericin B injections has not been previously reported...
October 20, 2016: Ophthalmic Plastic and Reconstructive Surgery
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