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https://www.readbyqxmd.com/read/28421399/effect-of-intravitreal-aflibercept-eylea-%C3%A2-on-retrobulbar-hemodynamics-in-patients-with-neovascular-age-related-macular-degeneration
#1
Mustafa Gok, Hasan Burhanettin Kapti
PURPOSE: To investigate the short-term effect of single intravitreal aflibercept injection on retrobulbar blood flow in patients with neovascular age-related macular degeneration (nAMD). METHODS: Twenty eyes of 20 patients with nAMD scheduled for single intravitreal aflibercept (Eylea(®)) injection and 20 fellow eyes (uninjected) were enrolled in this prospective interventional study. The hemodynamic parameters of the ophthalmic artery (OA), central retinal artery (CRA) and posterior ciliary artery (PCA) comprising peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI) were measured by using color Doppler ultrasonography (CDU) in both injected and uninjected fellow eyes at baseline and 1 week after the injection...
April 18, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28389165/cytomegalovirus-retinitis-followed-by-immune-recovery-uveitis-in-an-elderly-patient-with-rheumatoid-arthritis-undergoing-administration-of-methotrexate-and-tofacitinib-combination-therapy
#2
Kunio Yanagisawa, Yoshiyuki Ogawa, Mayumi Hosogai, Daisuke Todokoro, Takeki Mitsui, Akihiko Yokohama, Shoji Kishi, Hiroshi Handa
Cytomegalovirus (CMV) retinitis is an opportunistic ocular infection most commonly observed in patients infected with human immunodeficiency virus (HIV). We present a rare case of CMV retinitis that developed in a non-HIV patient with rheumatoid arthritis (RA). Over the preceding 5 months, a family doctor had been treating the 78-year-old male patient with a combination therapy of methotrexate (MTX) and tofacitinib (TOF). CMV retinitis occurred when the patient's CD4+ T cells were low (196 cells/μl), and preceded the onset of Pneumocystis pneumonia...
April 4, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28370143/inter-rater-reliability-of-sonographic-optic-nerve-sheath-diameter-measurements-by-emergency-medicine-physicians
#3
Stephanie Oberfoell, David Murphy, Andrew French, Stacy Trent, David Richards
OBJECTIVES: To compare the degree of agreement of sonographic optic nerve sheath diameter (ONSD) measurements by ultrasound fellowship-trained and resident emergency medicine (EM) physicians. METHODS: Ten ultrasound fellowship-trained EM attending physicians from multiple institutions and 51 resident EM physicians at a single residency were enrolled to measure the ONSD using a computerized ruler on five separate still-frame sonograms of adult eyes that included the retrobulbar optic nerve...
April 3, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28369019/in-vivo-effects-of-retrobulbar-bimatoprost-injection-on-orbital-fat
#4
Kian Eftekhari, M Reza Vagefi, Vivian Lee, James Z Hui, Menglong Zhu, Kimberly Dine, Richard L Anderson, Brigitte Koeberlein, Reas Sulaimankutty, Kenneth S Shindler
PURPOSE: Recent publications have reported the adverse effects of prostaglandin analogues on the periocular tissues. These medications may cause periorbital lipodystrophy, enophthalmos, and deepening of the superior sulcus deformity. While these effects may have adverse consequences for some patients, the atrophy of the periorbital fat may have a useful role in diseases that lead to orbital and periorbital fat hypertrophy such as thyroid eye disease. In this pilot study, the authors investigated the effects of retrobulbar bimatoprost injection on the intraocular pressure and orbital fat in a rat animal model...
March 31, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28367040/oral-administration-of-cilostazol-increases-ocular-blood-flow-in-patients-with-diabetic-retinopathy
#5
Duck Jin Hwang, Joo Young Shin, Hyeong Gon Yu
PURPOSE: To investigate the effect of cilostazol on ocular hemodynamics and to determine whether the administration of cilostazol increases the ocular blood flow in patients with diabetic retinopathy. METHODS: This prospective observational study investigated the effect of orally administered cilostazol on diabetic retinopathy. Before and after administration for 1 week, pulsatile ocular blood flow (POBF) and retrobulbar hemodynamics were measured using a POBF analyzer and transcranial Doppler imaging, respectively...
April 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28338555/retinal-detachment-and-retrobulbar-cysts-in-a-large-cohort-of-optic-nerve-coloboma
#6
Yufeng N Chen, C K Patel, Peter J Kertes, Robert G Devenyi, Susan Blaser, Wai-Ching Lam
PURPOSE: To examine the relationship between retinal detachment and retrobulbar cysts in patients with optic nerve coloboma (ONC) and Morning Glory syndrome (MGS). METHODS: Patients diagnosed with either ONC or MGS were identified through a search of the Sick Kids database. Seventy-one patients either agreed to come in for a B-scan or had an incidental orbital B-scan or magnetic resonance imaging or both. Eyes with orbital B-scan ultrasound and/or magnetic resonance imaging images were assessed independently by two ophthalmologists and a radiologist for the presence of retrobulbar cysts...
March 23, 2017: Retina
https://www.readbyqxmd.com/read/28333176/efficacy-of-retrobulbar-hyaluronidase-injection-for-vision-loss-resulting-from-hyaluronic-acid-filler-embolization
#7
Guo-Zhang Zhu, Zhong-Sheng Sun, Wen-Xiong Liao, Bing Cai, Chun-Lin Chen, Hui-Hui Zheng, Li Zeng, Sheng-Kang Luo
Background: Vision loss is a rare but serious complication of facial hyaluronic acid (HA) filler injection, for which there is no proven rescue therapy. Retrobulbar hyaluronidase injection is advocated by many plastic surgeons as an emergency treatment, but has not been carefully assessed for its efficacy. Objectives: To evaluate the efficacy of retrobulbar hyaluronidase injection as a rescue treatment for vision loss caused by HA filler embolization. Methods: Patients with vision loss caused by HA filler embolization were treated with retrobulbar hyaluronidase injection...
January 20, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28298866/choroidal-neovascularization-secondary-to-ocular-penetration-during-retrobulbar-anesthesia-and-its-treatment
#8
Seyhan Dikci, Turgut Yılmaz, Zarife Ekici Gök, Soner Demirel, Oğuzhan Genç
Retrobulbar anesthesia is still used before ocular surgery; however, it has various complications including ocular penetration. The penetration/perforation of the globe can cause complications such as endophthalmitis, retinal detachment, and scotoma. Choroidal neovascularization (CNV) is rarely seen, following choroidal rupture in penetrating eye injuries. Here, we present a patient who underwent a pars plana vitrectomy for vitreous hemorrhage secondary to ocular penetration during a retrobulbar injection for cataract surgery...
January 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28294507/exophthalmos-due-to-sterile-neutrophilic-dermatosis-in-a-dog
#9
Emily K Sharpe, Jessica M Meekins, Mary Bagladi-Swanson, Amy J Rankin
An 8-year-old castrated male Bichon Frise was presented to the Kansas State University Veterinary Health Center for evaluation of unilateral right-sided exophthalmos, suspected secondary to a retrobulbar abscess. The dog had acutely developed right-sided periorbital swelling, exophthalmos with pain on retropulsion, as well as multiple cutaneous exudative plaques on the feet and tail base. On ophthalmic examination, the dog also exhibited mild left-sided exophthalmos with decreased, nonpainful retropulsion. Orbital ultrasound and CT were performed to evaluate the extent of bilateral orbital disease...
March 14, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28277444/bilateral-retrobulbar-optic-neuropathy-associated-with-golimumab
#10
Marta de Frutos-Lezaun, Aritz Bidaguren, Patricia de la Riva, Carlos F Meneses, Javier Olascoaga
We report the first documented case of retrobulbar optic neuropathy associated with golimumab. A 48-year-old man was admitted with a 3-week history of progressive visual loss of his left eye. He had received a second infusion of golimumab for ankylosing spondylitis 10 days before admission. A magnetic resonance imaging scan showed enhancement of both optic nerves and visual evoked potentials were consistent with demyelinating bilateral optic neuropathy, although visual acuity drop in the right eye could not be determined because of deep amblyopia...
March 9, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28252457/acute-zonal-occult-outer-retinopathy-associated-with-retrobulbar-optic-neuritis
#11
Jay C Wang, Avni P Finn, Lindsay A Grotting, Lucia Sobrin
A 17-year-old girl presented with unilateral retrobulbar optic neuritis as well as bilateral funduscopic findings and outer retinal dysfunction suggestive of acute zonal occult outer retinopathy (AZOOR). Fundus autofluorescence abnormalities, visual field loss, and electroretinographic changes were supportive of bilateral AZOOR. MRI was consistent with the diagnosis of clinically isolated syndrome (CIS), which is defined as a central nervous system demyelinating event that may herald the onset of multiple sclerosis (MS)...
February 28, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28251170/presentation-of-massive-orbital-hidrocystoma-at-birth-case-report-and-review-of-the-literature
#12
Bahram Eshraghi, Mohammad-Ali Abtahi, Seyed Ali Sonbolastan, Zahra Kasaie, Seyed-Hossein Abtahi
BACKGROUND: Hidrocystoma, or sudoriferous cyst, is an eyelid tumor originating from apocrine or eccrine sweat glands. Its presence in the orbit is relatively rare. CASE PRESENTATION: A full-term female child with severe right eye extrusion was referred to our department two hours after birth. We performed cyst aspiration under ultrasonic guidance; 15 cc straw-colored fluid was obtained and proptosis resolved significantly. Orbital magnetic resonance imaging (MRI) showed a large unilocular retrobulbar mass with hypo-intensity in T1 and hyper-intensity in T2...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/28246307/pulmonary-function-and-retrobulbar-hemodynamics-in-subjects-with-type-2-diabetes-mellitus
#13
He Tai, Ming-Yue Wang, Yue-Ping Zhao, Ling-Bing Li, Xiao-Lin Jiang, Zheng Dong, Xiao-Nan Lv, Jing Liu, Qian-Yan Dong, Xin-Guang Liu, Jin-Song Kuang
BACKGROUND: The primary goals of this study were to evaluate early changes in pulmonary function and retrobulbar hemodynamics and to examine the correlation between these parameters in patients with type 2 diabetes during the preclinical stages of diabetic retinopathy. METHODS: For the single-time point measurements, 63 subjects with type 2 diabetes without diabetic retinopathy (diabetes group) and 32 healthy subjects (control group) were selected to evaluate any early changes in pulmonary function and retrobulbar hemodynamics and to examine the correlation between these parameters...
February 28, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28228407/retrobulbar-ocular-blood-flow-changes-measured-by-colour-doppler-imaging-after-intra-arterial-chemotherapy-in-retinoblastoma
#14
Kang Xue, Ailin Liu, Ren Hui, Jing Zhang, Jiang Qian
PURPOSE: To evaluate the effects of intra-arterial chemotherapy on retrobulbar blood flow parameters in patients with retinoblastoma. METHODS: This was a case-control study. 20 eyes of 10 patients with unilateral retinoblastoma that were treated with intra-arterial chemotherapy were evaluated using colour Doppler imaging. The peak systolic and end-diastolic velocities of the ophthalmic, central retinal and posterior ciliary arteries were determined. The pulsatility and resistance indices were calculated automatically...
February 22, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28215521/orbital-imaging-manifestations-of-neurocutaneous-syndromes-revisited
#15
REVIEW
Abanti Das, Sanjay Sharma
Neurocutaneous syndromes or phakomatoses represent a heterogeneous group of multisystemic disorders involving structures of ectodermal origin. Characteristic ocular manifestations are described for individual entities that are often the first clues to the underlying diagnosis. However, opaque ocular media or involvement of retrobulbar orbit limits adequate clinical evaluation. This underlines the role of imaging, especially cross-sectional imaging modalities, such as computed tomography and magnetic resonance imaging, which offer a comprehensive evaluation of orbit and its contents...
December 30, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28203195/27-gauge-vitrectomy-for-symptomatic-vitreous-floaters-with-topical-anesthesia
#16
Zhong Lin, Nived Moonasar, Rong Han Wu, Robin R Seemongal-Dass
PURPOSE: Traditionally acceptable methods of anesthesia for vitrectomy surgery are quite varied. However, each of these methods has its own potential for complications that can range from minor to severe. The surgery procedure of vitrectomy for symptomatic vitreous floaters is much simpler, mainly reflecting in the nonuse of sclera indentation, photocoagulation, and the apparently short surgery duration. The use of 27-gauge cannulae makes the puncture of the sclera minimally invasive...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28192644/perioperative-antibiotics-for-prevention-of-acute-endophthalmitis-after-cataract-surgery
#17
REVIEW
Emily W Gower, Kristina Lindsley, Samantha E Tulenko, Afshan A Nanji, Ilya Leyngold, Peter J McDonnell
BACKGROUND: Endophthalmitis is a severe inflammation of the anterior or posterior (or both) chambers of the eye that may be sterile or associated with infection. It is a potentially vision-threatening complication of cataract surgery. Prophylactic measures for endophthalmitis are targeted against various sources of infection. OBJECTIVES: To evaluate the effects of perioperative antibiotic prophylaxis for endophthalmitis following cataract surgery compared with no prophylaxis or other form of prophylaxis...
February 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28181367/periocular-breast-carcinoma-metastases-correlation-of-clinical-radiologic-and-histopathologic-features
#18
Natalie Homer, Frederick A Jakobiec, Anna Stagner, Mary Elizabeth Cunnane, Suzanne K Freitag, Aaron Fay, Michael K Yoon
IMPORTANCE: To describe presenting patterns of breast cancer metastases to the orbit and eyelids BACKGROUND: To provide clinical, radiographic, and pathologic correlations of breast metastases to the orbit or eyelids and evaluate radiographic volumetric orbital changes DESIGN: Retrospective review in an academic center PARTICIPANTS: Ten female patients with periocular metastatic breast carcinoma who were seen at the Massachusetts Eye and Ear Infirmary Oculoplastics Clinic METHODS: Retrospective review of patient records, imaging and pathology findings...
February 9, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28178099/surgical-treatment-of-retrobulbar-hematoma
#19
Jonathan Ribeiro, João Paulo Bonardi, Leonardo de Freitas Silva, Guto Fidalgo, Fabrizio Albieri, Nicolas Homsi, Hernando Valentim da Rocha-Júnior, Eduardo Hochuli-Vieira
No abstract text is available yet for this article.
February 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28145940/using-the-endoscopic-transconjunctival-and-transcaruncular-approach-to-repair-combined-orbital-floor-and-medial-wall-blowout-fractures
#20
Minwook Chang, Seong Won Yang, Jin-Hwan Park, Joonsik Lee, Hwa Lee, Min Soo Park, Sehyun Baek
PURPOSE: To demonstrate the effectiveness of the endoscopic transcaruncular and transconjunctival approach in the repair of combined medial and inferior orbital wall fractures. METHODS: A retrospective chart review was conducted on 160 patients with combined medial and inferior orbital wall fractures. All patients underwent surgery via an endoscopic transcaruncular and transconjunctival approach without lateral canthotomy, performed by a single surgeon. Porous polyethylene sheets (1...
January 31, 2017: Journal of Craniofacial Surgery
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