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https://www.readbyqxmd.com/read/28437761/negative-appraisals-and-fear-extinction-are-independently-related-to-ptsd-symptoms
#1
Daniel V Zuj, Matthew A Palmer, Kate E Gray, Chia-Ming K Hsu, Emma L Nicholson, Gin S Malhi, Richard A Bryant, Kim L Felmingham
BACKGROUND: Considerable research has revealed impaired fear extinction to be a significant predictor of PTSD. Fear extinction is also considered the primary mechanism of exposure therapy, and a critical factor in PTSD recovery. The cognitive theory of PTSD proposes that symptoms persist due to excessive negative appraisals about the trauma and its sequelae. Research has not yet examined the relationship between fear extinction and negative appraisals in PTSD. METHODS: A cross-sectional sample of participants with PTSD (n =21), and trauma-exposed controls (n =33) underwent a standardized differential fear conditioning and extinction paradigm, with skin conductance response (SCR) amplitude serving as the index of conditioned responses...
April 17, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28437693/an-assessment-of-the-social-cognitive-predictors-of-exclusive-breastfeeding-behavior-using-the-health-action-process-approach
#2
J L Martinez-Brockman, F M Shebl, N Harari, R Pérez-Escamilla
RATIONALE: In the United States rates of exclusive breastfeeding duration remain exceedingly low. Exclusive breastfeeding is a complex learned behavior that is influenced by social cognitive, interpersonal, and structural factors. Interventions are needed that address factors at multiple levels of the social-ecological model. This study was designed to examine the social cognitive predictors of exclusive breastfeeding behavior in a sample of low-income women attending the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) breastfeeding peer counseling program and enrolled in the Lactation Advice Through Texting Can Help (LATCH) study...
April 12, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28437528/automated-staging-of-age-related-macular-degeneration-using-optical-coherence-tomography
#3
Freerk G Venhuizen, Bram van Ginneken, Freekje van Asten, Mark J J P van Grinsven, Sascha Fauser, Carel B Hoyng, Thomas Theelen, Clara I Sánchez
Purpose: To evaluate a machine learning algorithm that automatically grades age-related macular degeneration (AMD) severity stages from optical coherence tomography (OCT) scans. Methods: A total of 3265 OCT scans from 1016 patients with either no signs of AMD or with signs of early, intermediate, or advanced AMD were randomly selected from a large European multicenter database. A machine learning system was developed to automatically grade unseen OCT scans into different AMD severity stages without requiring retinal layer segmentation...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28437438/use-of-the-matrics-consensus-cognitive-battery-mccb-to-evaluate-cognitive-deficits-in-bipolar-disorder-a-systematic-review-and-meta-analysis
#4
Qijing Bo, Zhen Mao, Xianbin Li, Zhimin Wang, Chuanyue Wang, Xin Ma
BACKGROUND: The Measurement and Treatment Research to Improve Cognition Schizophrenia Consensus Cognitive Battery (MCCB) has also been proposed for use in clinical trials to assess cognitive deficits in patients with bipolar disorder (BD). The aim of this study was to evaluate cognitive function assessed by the MCCB in BD. METHODS: A literature search of the PubMed, Embase, PsycINFO, SCI, Cochrane Library databases and the Cochrane Controlled Trials Register was conducted...
2017: PloS One
https://www.readbyqxmd.com/read/28437316/attitudes-of-physician-assistant-educators-toward-interprofessional-education-and-collaborative-care
#5
Laura A Levy, Kathleen Mathieson
PURPOSE: Interprofessional education (IPE) has been shown to improve collaboration in the workforce, ultimately improving patient care. The purpose of this study was to evaluate physician assistant (PA) educators' attitudes toward IPE and interprofessional (IP) health care teams. METHODS: An online survey was sent to 1198 PA educators. The survey assessed 3 domains: attitudes toward IPE, attitudes toward IP health care teams, and attitudes toward IP learning in the academic setting...
April 21, 2017: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/28436741/deep-learning-at-chest-radiography-automated-classification-of-pulmonary-tuberculosis-by-using-convolutional-neural-networks
#6
Paras Lakhani, Baskaran Sundaram
Purpose To evaluate the efficacy of deep convolutional neural networks (DCNNs) for detecting tuberculosis (TB) on chest radiographs. Materials and Methods Four deidentified HIPAA-compliant datasets were used in this study that were exempted from review by the institutional review board, which consisted of 1007 posteroanterior chest radiographs. The datasets were split into training (68.0%), validation (17.1%), and test (14.9%). Two different DCNNs, AlexNet and GoogLeNet, were used to classify the images as having manifestations of pulmonary TB or as healthy...
April 24, 2017: Radiology
https://www.readbyqxmd.com/read/28436703/in-the-driver-s-seat-development-and-implementation-of-an-e-learning-module-on-return-to-driving-after-stroke
#7
Janet Frith, Isobel Hubbard, Carole James, Helen Warren-Forward
Gaps exist in the knowledge of return-to-driving guidelines, and education is needed for Australian health professionals working in the field of stroke. In this paper, authors evaluate the implementation of an e-learning module. A pre- and post-module knowledge test and survey were used to assess the e-module's success in achieving its learning objectives. Initially, 204 learners completed the module, with 68% of learners scoring 100% in the post-module knowledge test. Only 12 learners completed the survey...
April 24, 2017: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/28436072/real-time-individualization-of-the-unified-model-of-performance
#8
Jianbo Liu, Sridhar Ramakrishnan, Srinivas Laxminarayan, Thomas J Balkin, Jaques Reifman
Existing mathematical models for predicting neurobehavioural performance are not suited for mobile computing platforms because they cannot adapt model parameters automatically in real time to reflect individual differences in the effects of sleep loss. We used an extended Kalman filter to develop a computationally efficient algorithm that continually adapts the parameters of the recently developed Unified Model of Performance (UMP) to an individual. The algorithm accomplishes this in real time as new performance data for the individual become available...
April 24, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28435986/asian-consortium-on-radiation-dose-of-pediatric-cardiac-ct-asci-redcard
#9
Peter K T Hui, Hyun Woo Goo, Jing Du, Janice J K Ip, Suzu Kanzaki, Young Jin Kim, Supika Kritsaneepaiboon, Oktavia Lilyasari, Suvipaporn Siripornpitak
BACKGROUND: With incremental utilization of pediatric cardiac CT in congenital heart disease, it is imperative to define its current radiation dose levels in clinical practice in order to help imagers optimize CT protocols, particularly in Asia and other developing countries where CT physicists are not readily available. OBJECTIVE: To evaluate current radiation dose levels and influencing factors in cardiac CT in children with congenital heart disease in Asia by conducting a retrospective multi-center, multi-vendor study...
April 24, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28435975/-effect-of-bilateral-injection-of-calcitonin-gene-related-peptide-into-amygdala-on-learning-and-memory-of-mice
#10
Xin Wu, Wan-Jun Zheng, Ming-Hui Lv, Jian-Feng Gao
The aim of the present study was to explore the effects of different doses of calcitonin gene-related peptide (CGRP) injected into the central nucleus of amygdala on cognitive function, learning and memory of mice. C57BL/6J mice (30 days old) were randomly divided into control, sham, and three CGRP groups (10 mice for each group). Three doses of CGRP (200, 400 and 800 ng) were bilaterally administered into the central nucleus of the amygdala. Open field test was used to assess cognitive function. Novel object recognition and Morris water maze test were used to evaluate learning and memory of the mice...
April 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/28435916/feasibility-of-endoscopic-discectomy-by-inter-laminar-approach-at-a-high-volume-tertiary-public-hospital-in-a-developing-country
#11
Shardul Madhav Soman, Jayprakash Vrajlal Modi, Jimmy Chokshi
BACKGROUND: Surgical treatment for lumbar disc herniation consists of discectomy performed either open or minimally invasive techniques. Endoscopic discectomy using the tubular retractor is been increasingly used as it gives advantage of smaller incision, less tissue injury and faster recovery. The aim of this study was to check its feasibility and learning curve at a tertiary public sector hospital with a large volume load (more than 50 spine surgeries per month) with treatment provided free of cost...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28435815/perception-of-hiv-aids-education-at-the-community-level-in-jordan
#12
Fathieh Abu Moghli, Suhair Al Habeesh, Lubna Abu Shikha
BACKGROUND: The control of spread of HIV takes concerted efforts at both national and international levels. Education is an important component of preventing the spread of HIV. This study aimed to assess the attitudes of parents, teachers and students towards informing children about HIV/AIDS, attitudes concerning 'proper' age to learn about HIV/AIDS, possible differences in attitudes relating to gender of child and what they should learn and ideas about the most 'adequate' person/institution to be responsible for provision of HIV/AIDS education...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28435745/a-consult-service-to-support-and-promote-community-based-research-tracking-and-evaluating-a-community-based-research-consult-service
#13
Clara M Pelfrey, Katrice D Cain, Mary Ellen Lawless, Earl Pike, Ashwini R Sehgal
PURPOSE: This study describes the design, operation and evaluation of a community-based research (CBR) consult service within the setting of a Clinical and Translational Science Award (CTSA) institution. To our knowledge, there are no published evaluations of a CBR consult service at a CTSA hub. METHODS: A community-based research Consult Service was created to support faculty, health care providers/research coordinators, trainees, community-based organizations and community members...
February 2017: J Clin Transl Sci
https://www.readbyqxmd.com/read/28434973/long-term-oral-kinetin-does-not-protect-against-%C3%AE-synuclein-induced-neurodegeneration-in-rodent-models-of-parkinson-s-disease
#14
Adam L Orr, Florentine U Rutaganira, Daniel de Roulet, Eric J Huang, Nicholas T Hertz, Kevan M Shokat, Ken Nakamura
Mutations in the mitochondrial kinase PTEN-induced putative kinase 1 (PINK1) cause Parkinson's disease (PD), likely by disrupting PINK1's kinase activity. Although the mechanism(s) underlying how this loss of activity causes degeneration remains unclear, increasing PINK1 activity may therapeutically benefit some forms of PD. However, we must first learn whether restoring PINK1 function prevents degeneration in patients harboring PINK1 mutations, or whether boosting PINK1 function can offer protection in more common causes of PD...
April 20, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28434911/does-quantity-ensure-quality-standardized-osce-stations-for-outcome-oriented-evaluation-of-practical-skills-at-different-medical-faculties
#15
Iris Schleicher, Karsten Leitner, Jana Juenger, Andreas Moeltner, Miriam Ruesseler, Bernd Bender, Jasmina Sterz, Tina Stibane, Sarah Koenig, Susanne Frankenhauser, Joachim Gerhard Kreuder
BACKGROUND: Practical skills are often assessed using Objective Structured Clinical Skill Exams (OSCE). Nevertheless, in Germany, interchange and agreement between different medical faculties or a general agreement on the minimum standard for passing is lacking. METHODS: We developed standardized OSCE-stations for assessing structured clinical examination of knee and shoulder joint with identical checklists and evaluation standards. These were implemented into the OSCE-course at five different medical faculties...
April 20, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28434885/early-performance-on-an-eye-surgery-simulator-predicts-subsequent-resident-surgical-performance
#16
Ramak Roohipoor, Mehdi Yaseri, Amir Teymourpour, Carolyn Kloek, John B Miller, John I Loewenstein
OBJECTIVE: To examine early performance on an eye surgery simulator and its relationship to subsequent live surgical performance in a single large residency program. DESIGN: Retrospective study. SETTING: Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology. METHODS: In a retrospective study, we compared performance of 30 first-year ophthalmology residents on an eye surgery simulator to their surgical skills as third-year residents...
April 20, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28434754/-patient-safety-culture-in-family-practice-residents-of-galicia
#17
Manuel Portela Romero, Rosendo Bugarín González, María Sol Rodríguez Calvo
OBJECTIVE: To determine the views held by Family practice (FP) residents on the different dimensions of patient safety, in order to identify potential areas for improvement. DESIGN: A cross-sectional study. LOCATION: Seven FP of Galicia teaching units. PARTICIPANTS: 182 FP residents who completed the Medical Office Survey on Patient Safety Culture questionnaire. MEASUREMENTS: The Medical Office Survey on Patient Safety Culture questionnaire was chosen because it is translated, validated, and adapted to the Spanish model of Primary Care...
April 20, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28434586/the-periaqueductal-gray-and-primal-emotional-processing-critical-to-influence-complex-defensive-responses-fear-learning-and-reward-seeking
#18
REVIEW
Simone C Motta, Antônio P Carobrez, Newton S Canteras
The periaqueductal gray (PAG) has been commonly recognized as a downstream site in neural networks for the expression of a variety of behaviors and is thought to provide stereotyped responses. However, a growing body of evidence suggests that the PAG may exert more complex modulation of a number of behavioral responses and work as a unique hub supplying primal emotional tone to influence prosencephalic sites mediating complex aversive and appetitive responses. Of particular relevance, we review how the PAG is involved in influencing complex forms of defensive responses, such as circa-strike and risk assessment responses in animals...
May 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28434459/becoming-parent-and-nurse-high-fidelity-simulation-in-teaching-ambulatory-central-line-infection-prevention-to-parents-of-children-with-cancer
#19
Carol E Heiser Rosenberg, Mary F Terhaar, Judith A Ascenzi, Anna Walbert, K Michelle Kokoszka, Julianne S Perretta, Marlene R Miller
BACKGROUND: Ambulatory central-line infections in children with cancer are life-threatening. Infections are two to three times more frequent in outpatients than inpatients, for whom evidence-based bundles have decreased morbidity. Most cancer care now takes place at home, where parents perform many of the same tasks as nurses. However, parents often feel stressed and unprepared. To address this, high-fidelity simulation, which has been effective for teaching novice nurses, was evaluated for parent central-line education...
May 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28434251/a-mock-randomized-controlled-trial-with-audience-response-technology-for-teaching-and-learning-epidemiology
#20
Philip R A Baker, Daniel P Francis, Abby Cathcart
The study's objective was to apply and assess an active learning approach to epidemiology and critical appraisal. Active learning comprised a mock, randomized controlled trial (RCT) conducted with learners in 3 countries. The mock trial consisted of blindly eating red Smarties candy (intervention) compared to yellow Smarties (control) to determine whether red Smarties increase happiness. Audience response devices were employed with the 3-fold purposes to produce outcome data for analysis of the effects of red Smarties, identify baseline and subsequent changes in participant's knowledge and confidence in understanding of RCTs, and assess the teaching approach...
April 2017: Asia-Pacific Journal of Public Health
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