Melis Yavuz, Ekin Dongel Dayanc, Fatma Merve Antmen, Elif Keskinöz, Esra Altuntaş, Gökçen Dolu, Berkcan Koç, Emre Tunçcan, Damla Şakar, Ufuk Canözer, Ceyda Büyüker, Ece Polat, Metincan Erkaya, Rui Azevedo, Devrim Öz Arslan, Agostinho Almeida, Güldal Süyen
Introduction: This study investigates the effects of social isolation on mental health and cognitive functions in Sprague Dawley (SD) and Wistar Albino (WIS) rat strains, prompted by the heightened awareness of such impacts amid the COVID-19 pandemic. This study aims to explore the impact of social isolation on memory, learning, and behavioral changes in middle-aged SD and WIS rat strains and to investigate cortical trace element levels, seeking potential correlations between these levels and the observed behavioral responses to social isolation...
2024: Frontiers in Pharmacology