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Phantom limb pain

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https://www.readbyqxmd.com/read/27887967/percutaneous-image-guided-cryoablation-for-the-treatment-of-phantom-limb-pain-in-amputees-a-pilot-study
#1
J David Prologo, Charles A Gilliland, Michael Miller, Paul Harkey, Jackie Knight, Darren Kies, C Matthew Hawkins, David Corn, David K Monson, Faramarz Edalat, Sean Dariushnia, Luke Brewster
PURPOSE: To prospectively evaluate percutaneous image-guided nerve cryoablation for treatment of refractory phantom limb pain (PLP) in a pilot cohort for purposes of deriving parameters to design a larger, randomized, parallel-armed, controlled trial. MATERIALS AND METHODS: From January 2015 to January 2016, 21 patients with refractory PLP underwent image-guided percutaneous cryoneurolysis procedures. Visual analog scale scores were documented at baseline and 7, 45, and 180 days after the procedure...
November 22, 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27834472/diagnosis-and-treatment-of-pain-in-plexopathy-radiculopathy-peripheral-neuropathy-and-phantom-limb-pain-evidence-and-recommendations-from-the-italian-consensus-conference-on-pain-on-neurorehabilitation
#2
Francesco Ferraro, Marco Jacopetti, Vincenza Spallone, Luca Padua, Marco Traballesi, Stefano Brunelli, Cristina Cantarella, Cristina Ciotti, Daniele Coraci, Elena Dalla Toffola, Silvia Mandrini, Giovanni Morone, Costanza Pazzaglia, Marcello Romano, Angelo Schenone, Rossella Togni, Stefano Tamburin
Pain may affect all aspects of social life and reduce the quality of life. Neuropathic pain (NP) is common in patients affected by plexopathy, radiculopathy, mononeuropathy, peripheral neuropathy. Phantom limb pain (PLP) is a painful sensation that is common after amputation, and its pathophysiological mechanisms involve changes in the peripheral and central nervous system. Given the lack of conclusive evidence and specific guidelines on these topics, the aim of the Italian Consensus Conference on Pain on Neurorehabilitation (ICCPN) was to collect evidence and offer recommendations to answer currently open questions on the assessment and treatment of NP associated with the above conditions and PLP...
November 11, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27819420/effect-of-co-morbid-conditions-on-persistent-neuropathic-pain-after-brachial-plexus-injury-in-adult-patients
#3
Asish Subedi, Pongparadee Chaudakshetrin, Haruthai Chotisukarat, Sahatsa Mandee
BACKGROUND AND PURPOSE: Neuropathic pain (NeuP) associated with traumatic brachial plexus injury (BPI) can be severe, persistent, and resistant to treatment. Moreover, comorbidity associated with NeuP may worsen the pain and quality of life. This study compared persistent NeuP after BPI between patients with and without co-morbid conditions (psychiatric dysfunction and other painful conditions) and tramadol usage as a second-line agent in combination with an antiepileptic and/or antidepressant during a 2-year follow-up...
October 2016: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/27813692/memantine-for-the-treatment-of-phantom-limb-pain-a-systematic-review
#4
Brittany M Loy, Rachel B Britt, Jamie N Brown
Phantom limb pain (PLP) occurs in up to 85% of patients who have undergone an amputation and remains difficult to treat. Memantine is a N-Methyl-d-aspartate receptor antagonist that has shown benefit in pain syndromes. The objective of this systematic review is to evaluate the evidence for the use of memantine in the treatment of acute and chronic PLP. MEDLINE (1956 to May 2016) and Embase (1957 to May 2016) were queried for articles that characterized the clinical outcomes of patient(s) treated with memantine for PLP...
November 4, 2016: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/27813030/the-effect-of-mirror-therapy-on-the-management-of-phantom-limb-pain
#5
Meltem Yıldırım, Nevin Kanan
OBJECTIVES: In the last two decades, mirror therapy has become a frequently used method of managing phantom limb pain (PLP). However, the role of nurses in mirror therapy has not yet been well defined. This study examined the effect of mirror therapy on the management of PLP, and discusses the importance of mirror therapy in the nursing care of amputee patients. METHODS: This quasi-experimental study was conducted in the pain management department of a university hospital and a prosthesis clinic in İstanbul, Turkey, with 15 amputee patients who had PLP...
July 2016: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/27807349/induced-sensorimotor-brain-plasticity-controls-pain-in-phantom-limb-patients
#6
Takufumi Yanagisawa, Ryohei Fukuma, Ben Seymour, Koichi Hosomi, Haruhiko Kishima, Takeshi Shimizu, Hiroshi Yokoi, Masayuki Hirata, Toshiki Yoshimine, Yukiyasu Kamitani, Youichi Saitoh
The cause of pain in a phantom limb after partial or complete deafferentation is an important problem. A popular but increasingly controversial theory is that it results from maladaptive reorganization of the sensorimotor cortex, suggesting that experimental induction of further reorganization should affect the pain, especially if it results in functional restoration. Here we use a brain-machine interface (BMI) based on real-time magnetoencephalography signals to reconstruct affected hand movements with a robotic hand...
October 27, 2016: Nature Communications
https://www.readbyqxmd.com/read/27782861/acupuncture-for-the-treatment-of-phantom-limb-syndrome-in-lower-limb-amputees-a-randomised-controlled-feasibility-study
#7
Esmé G Trevelyan, Warren A Turner, Lynn Summerfield-Mann, Nicola Robinson
BACKGROUND: Post amputation, the complication of phantom limb pain (PLP) is prevalent and difficult to manage. This study aimed to determine whether it was feasible and acceptable to undertake a definitive multicentred randomised controlled trial assessing the effectiveness of acupuncture for treating lower limb amputees with PLP. METHODS: A mixed-methods embedded design, including a randomised controlled trial and semistructured interviews, was undertaken. A total of 15 participants with PLP were randomly assigned to receive either eight pragmatic Traditional Chinese Medicine acupuncture treatments and usual care or usual care alone over 4 weeks...
October 25, 2016: Trials
https://www.readbyqxmd.com/read/27780402/a-systematic-review-on-the-treatment-of-phantom-limb-pain-with-spinal-cord-stimulation
#8
Rohit Aiyer, Robert L Barkin, Anurag Bhatia, Semih Gungor
: Phantom limb pain (PLP) is a challenging chronic pain syndrome to treat with pharmacologic agents being first line of management. However, when these agents fail to provide pain relief, other interventions must be considered in a clinical setting. Spinal cord stimulation (SCS) has been shown to provide analgesia in PLP, and should be considered by clinicians. METHODS: This PRISMA systematic review analyzes the efficacy of SCS for treatment of PLP. RESULTS: After review of 12 studies, there are mixed results to base a conclusion on...
January 2017: Pain Management
https://www.readbyqxmd.com/read/27742450/cross-sectional-assessment-of-factors-related-to-pain-intensity-and-pain-interference-in-lower-limb-prosthesis-users
#9
Sara J Morgan, Janna L Friedly, Dagmar Amtmann, Rana Salem, Brian J Hafner
OBJECTIVE: To determine relationships between pain sites and pain intensity/interference in people with lower limb amputations (LLAs). DESIGN: Cross-sectional survey. SETTING: Community. PARTICIPANTS: Lower limb prosthesis users with unilateral or bilateral amputations (N=1296; mean time since amputation, 14.1y). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Patient-Reported Outcomes Measurement Information System (PROMIS) pain intensity (1 item to assess average pain), PROMIS pain interference (4-item short form to assess the consequences of pain in desired activities), and questions that asked participants to rate the extent to which each of the following were a problem: residual limb pain (RLP), phantom limb pain (PLP), knee pain on the nonamputated side, back pain, and shoulder pain...
October 11, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27737513/pharmacologic-interventions-for-treating-phantom-limb-pain
#10
REVIEW
Maria Jenelyn M Alviar, Tom Hale, Monalisa Dungca
BACKGROUND: This is an updated version of the original Cochrane review published in Issue 12, 2011. Phantom limb pain (PLP) is pain that arises in the missing limb after amputation and can be severe, intractable, and disabling. Various medications have been studied in the treatment of phantom pain. There is currently uncertainty in the optimal pharmacologic management of PLP. OBJECTIVES: This review aimed to summarise the evidence of effectiveness of pharmacologic interventions in treating PLP...
October 14, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27676814/the-effects-of-mirror-therapy-on-pain-and-motor-control-of-phantom-limb-in-amputees-a-systematic-review
#11
Jessie Barbin, Vanessa Seetha, Jean-Marie Casillas, Jean Paysant, Dominic Perennou
OBJECTIVE: Phantom limb pain (PLP) is a major problem after limb amputation. Mirror therapy (MT) is a non-pharmacological treatment using representations of movement, the efficacy of which in reducing PLP remains to be clarified. Here, we present the first systematic review on MT efficacy in phantom limb pain (PLP) and phantom limb movement (PLM) in amputees (lower or upper limb). MATERIAL/PATIENTS AND METHODS: A search on MEDLINE, COCHRANE DATABASE and EMBASE, crossing the key words "phantom limb" and "mirror therapy" found studies which were read and analyzed according the PRISMA statement...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27673145/poster-394-treatment-of-recalcitrant-phantom-limb-pain-with-alpha-stimulation%C3%A2-a-case-report
#12
Daniel Z Contract, Deborah M Caruso
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27646840/altered-white-matter-and-sensory-response-to-bodily-sensation-in-female-to-male-transgender-individuals
#13
Laura K Case, David Brang, Rosalynn Landazuri, Pavitra Viswanathan, Vilayanur S Ramachandran
While most people take identification with their body for granted, conditions such as phantom limb pain, alien hand syndrome, and xenomelia suggest that the feeling of bodily congruence is constructed and susceptible to alteration. Individuals with xenomelia typically experience one of their limbs as over-present and aversive, leading to a desire to amputate the limb. Similarly, many transgender individuals describe their untreated sexed body parts as incongruent and aversive, and many experience phantom body parts of the sex they identify with (Ramachandran, 2008)...
September 19, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27590967/multisession-noninvasive-closed-loop-neuroprosthetic-control-of-grasping-by-upper-limb-amputees
#14
H A Agashe, A Y Paek, J L Contreras-Vidal
Upper limb amputation results in a severe reduction in the quality of life of affected individuals due to their inability to easily perform activities of daily living. Brain-machine interfaces (BMIs) that translate grasping intent from the brain's neural activity into prosthetic control may increase the level of natural control currently available in myoelectric prostheses. Current BMI techniques demonstrate accurate arm position and single degree-of-freedom grasp control but are invasive and require daily recalibration...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27582042/the-effects-of-graded-motor-imagery-and-its-components-on-phantom-limb-pain-and-disability-in-upper-and-lower-limb-amputees-a-systematic-review-protocol
#15
Katleho Limakatso, Lieselotte Corten, Romy Parker
BACKGROUND: Phantom limb pain (PLP) is characterized by the anatomical shifting of neighbouring somatosensory and motor areas into a deafferented cortical area of the brain contralateral to the amputated limb. It has been shown that maladaptive neuroplasticity is positively correlated to the perception of PLP in amputees. Recent studies support the use of graded motor imagery (GMI) and its component to alleviate the severity of PLP and disability. However, there is insufficient collective empirical evidence exploring the effectiveness of these treatment modalities in amputees with PLP...
2016: Systematic Reviews
https://www.readbyqxmd.com/read/27576865/-chronic-pain-perception-reward-and-neural-processing
#16
S Becker, M Diers
Many chronic pain syndromes are characterized by enhanced perception of painful stimuli as well as alterations in cortical processing in sensory and motor regions. In this review article the alterations in muscle pain and neuropathic pain are described. Alterations in patients with fibromyalgia and chronic back pain are described as examples for musculoskeletal pain and also in patients with phantom limb pain after amputation and complex regional pain syndrome as examples for neuropathic pain. In addition to altered pain perception, cumulative evidence on alterations in the processing of reward and the underlying mechanisms in chronic pain has been described...
October 2016: Der Schmerz
https://www.readbyqxmd.com/read/27566812/pain-management-in-patients-with-vascular-disease
#17
M Seretny, L A Colvin
Vascular disease covers a wide range of conditions, including arterial, venous, and lymphatic disorders, with many of these being more common in the elderly. As the population ages, the incidence of vascular disease will increase, with a consequent increase in the requirement to manage both acute and chronic pain in this patient population. Pain management can be complex, as there are often multiple co-morbidities to be considered. An understanding of the underlying pain mechanisms is helpful in the logical direction of treatment, particularly in chronic pain states, such as phantom limb pain or complex regional pain syndrome...
September 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/27554530/deep-brain-stimulation-of-the-periaqueductal-gray-releases-endogenous-opioids-in-humans
#18
Hugh Sims-Williams, Julian C Matthews, Peter S Talbot, Sarah Love-Jones, Jonathan Cw Brooks, Nikunj K Patel, Anthony E Pickering
Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous opioids to exert its analgesic effect using [(11)C]diprenorphine (DPN) positron emission tomography (PET). Patients with de-afferentation pain (phantom limb pain or Anaesthesia Dolorosa (n=5)) who obtained long-lasting analgesic benefit from DBS were recruited. [(11)C]DPN and [(15)O]water PET scanning was performed in consecutive sessions; first without, and then with PAG stimulation...
August 21, 2016: NeuroImage
https://www.readbyqxmd.com/read/27551416/perceptions-of-phantom-limb-pain-in-lower-limb-amputees-and-its-effect-on-quality-of-life-a-qualitative-study
#19
Esmé G Trevelyan, Warren A Turner, Nicola Robinson
BACKGROUND: Phantom limb pain (PLP) is a prevalent complication post-amputation. Currently, qualitative literature exploring the experience of PLP in amputees is sparse, and little is known about whether the educational needs of amputees are being met. OBJECTIVES: To explore lower limb amputees' descriptive lived experiences of PLP, to understand how PLP affects quality of life and to determine whether amputees feel they are provided with adequate information about PLP...
May 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27547774/reversal-of-phantom-pain-and-hand-to-face-remapping-after-brachial-plexus-avulsion
#20
Jack W Tsao, Sacha B Finn, Matthew E Miller
Following left brachial plexus avulsion, a 20-year-old man had phantom limb pain and remapping of sensation from his paralyzed hand onto his face. Mirror therapy (15 min daily, 5 days/week) led immediately to good movement of the phantom limb with decreased pain. Within 2 weeks following nerve graft surgery, remapping of hand sensation onto the face disappeared along with resolution of phantom limb pain. Mirror therapy coupled with nerve grafting may relieve phantom limb pain due to brachial plexus avulsion and reverse hand-to-face remapping, suggesting that both peripheral and central mechanisms mediate development of phantom limb pain and cortical reorganization/neuroplasticity after brachial plexus avulsion...
June 2016: Annals of Clinical and Translational Neurology
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