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https://www.readbyqxmd.com/read/28900756/systematic-review-of-interventions-for-depression-for-people-living-with-hiv-in-africa
#1
REVIEW
Sarah M Lofgren, Noeline Nakasujja, David R Boulware
Depression interventions for individuals with HIV/AIDS in Africa are being increasingly evaluated. MEDLINE was searched using key terms: depression, Africa, and HIV, to identify depression interventions for HIV-infected adults in Africa. Perinatal women were excluded. Results were extracted and relative change in depression scores for interventions and net effect calculated. The MEDLINE search yielded 18 articles. Six of seven studies evaluating feasibility were positive, and seven of seven studies evaluating acceptability were also positive...
September 12, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28899162/high-levels-of-viral-suppression-among-east-african-hiv-infected-women-and-men-in-serodiscordant-partnerships-initiating-antiretroviral-therapy-with-high-cd4-counts-and-during-pregnancy
#2
Andrew Mujugira, Jared Baeten, Lara Kidoguchi, Jessica Haberer, Connie Celum, Deborah Donnell, Kenneth Ngure, Elizabeth Bukusi, Nelly Mugo, Stephen Asiimwe, Josephine Odoyo, Edna Tindimwebwa, Nulu Bulya, Elly Katabira, Renee Heffron
BACKGROUND: People who are asymptomatic and feel healthy, including pregnant women, may be less motivated to initiate ART or achieve high adherence. We assessed whether ART initiation, and viral suppression 6, 12 and 24-months after ART initiation, were lower in HIV-infected members of serodiscordant couples who initiated during pregnancy or with higher CD4 counts. METHODS: We used data from the Partners Demonstration Project, an open-label study of the delivery of integrated PrEP and ART (at any CD4 count) for HIV prevention among high-risk HIV serodiscordant couples in Kenya and Uganda...
September 13, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28895487/-%C3%A2-like-because-you-are-a-grownup-you-do-not-need-help-experiences-of-transition-from-pediatric-to-adult-care-among-youth-with-perinatal-hiv-infection-their-caregivers-and-health-care-providers-in-the-dominican-republic
#3
María C Pinzón-Iregui, Gladys Ibanez, Consuelo Beck-Sagué, Mina Halpern, Rosa M Mendoza
With the introduction of combination antiretroviral therapy (ART) worldwide, youth with perinatal HIV infection are increasingly surviving childhood and transitioning to adult care. Although a normal life span is anticipated posttransition, successful transition to adult HIV care has proven difficult, with worse outcomes posttransition than in pediatric and adult care. This study is a qualitative analysis of data from 4 focus groups of pre- and posttransition patients, caregivers, and healthcare providers in the Dominican Republic at an institution that provides comprehensive treatment including ART for HIV-infected persons of all ages...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28891343/current-and-future-contraceptive-options-for-women-living-with-hiv
#4
Rena C Patel, Elizabeth A Bukusi, Jared M Baeten
Among women living with HIV, half of the pregnancies are unintended. Effective contraception can prevent unintended pregnancies and consequently reduce maternal mortality and perinatal transmission of HIV. While contraceptive options available for all women also apply to women living with HIV, specific considerations exist to the use of contraception by women living with HIV. Areas covered: First, general principles guiding the use of contraception among women living with HIV are discussed, such as choice, method mix, relative effectiveness, and drug-drug interactions...
September 11, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28885420/a-missed-opportunity-for-u-s-perinatal-human-immunodeficiency-virus-elimination-pre-exposure-prophylaxis-during-pregnancy
#5
Timothee Fruhauf, Jenell S Coleman
OBJECTIVE: To estimate the proportion of women at increased risk of sexual human immunodeficiency virus (HIV) acquisition during pregnancy in a high HIV incidence urban setting to identify those who may be eligible for pre-exposure prophylaxis. METHODS: We conducted a retrospective cohort study of women who received prenatal care at a large academic center in 2012. Univariable analyses and multiple logistic regression models were built to identify correlates for pre-exposure prophylaxis eligibility...
September 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28841701/pregnancy-outcomes-in-perinatally-hiv-infected-young-women-in-madrid-spain-2000-2015
#6
Luis M Prieto, Carolina Fernández McPhee, Patricia Rojas, Diana Mazariegos, Eloy Muñoz, Maria José Mellado, África Holguín, María Luisa Navarro, María Isabel González-Tomé, José Tomás Ramos
BACKGROUND: An increasing number of perinatally HIV-infected women (PHIV) are reaching adulthood and becoming pregnant. Most PHIV women have been exposed to a high number of antiretroviral regimens, and they may have difficulties to achieve viral suppression. Psychosocial problems are not uncommon and could be an important barrier for treatment adherence. The effects of chronic HIV infection and long-term exposure to antiretroviral treatment of PHIV women cause concerns on the developing fetus...
2017: PloS One
https://www.readbyqxmd.com/read/28832781/health-transition-in-brazil-regional-variations-and-divergence-convergence-in-mortality
#7
Gabriel Mendes Borges
This study analyzes the main characteristics of the health transition in Brazil and its five major regions, using a framework that accounts for regional inequalities in mortality trends. The regional mortality divergence/convergence process is described and discussed by considering the specific contributions of age groups and causes of death in life expectancy variations. Results show that mortality change in Brazil has follow the epidemiologic transition theory to some extent during the period under analysis - for instance, the sharp decline in infant mortality in all regions (first from infectious and parasitic diseases and then from causes associated with the perinatal period) and the increase in the participation of chronic and degenerative diseases as the main cause of death...
August 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28821230/seroprevalence-of-herpes-simplex-virus-type-2-hsv-2-among-pregnant-women-who-participated-in-a-national-hiv-surveillance-activity-in-haiti
#8
Jean Wysler Domercant, Frantz Jean Louis, Erin Hulland, Mark Griswold, Jocelyne Andre-Alboth, Tun Ye, Barbara J Marston
BACKGROUND: Herpes simplex virus type 2 (HSV-2), one the most common causes of genital ulcers, appears to increase both the risk of HIV acquisition and HIV transmission. HSV-2/HIV co-infection among pregnant women may increase the risk of perinatal transmission of HIV. This study describes rates of HSV-2 among pregnant women in Haiti and HSV-2 test performance in this population. METHODS: Unlinked residual serum specimens from the 2012 National HIV and Syphilis Sentinel Surveillance Survey among pregnant women in Haiti were tested using two commercial kits (Focus HerpeSelect, Kalon) for HSV-2 antibodies...
August 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28807190/socioeconomic-differences-in-mortality-in-the-antiretroviral-therapy-era-in-agincourt-rural-south-africa-2001-13-a-population-surveillance-analysis
#9
Chodziwadziwa W Kabudula, Brian Houle, Mark A Collinson, Kathleen Kahn, Francesc Xavier Gómez-Olivé, Stephen Tollman, Samuel J Clark
BACKGROUND: Understanding the effects of socioeconomic disparities in health outcomes is important to implement specific preventive actions. We assessed socioeconomic disparities in mortality indicators in a rural South African population over the period 2001-13. METHODS: We used data from 21 villages of the Agincourt Health and socio-Demographic Surveillance System (HDSS). We calculated the probabilities of death from birth to age 5 years and from age 15 to 60 years, life expectancy at birth, and cause-specific and age-specific mortality by sex (not in children <5 years), time period, and socioeconomic status (household wealth) quintile for HIV/AIDS and tuberculosis, other communicable diseases (excluding HIV/AIDS and tuberculosis) and maternal, perinatal, and nutritional causes, non-communicable diseases, and injury...
September 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28799825/progress-toward-elimination-of-perinatal-hiv-transmission-in-kenya-analysis-of-early-infant-diagnosis-data
#10
Dunstan Achwoka, Justin Mandala, Mutugi Muriithi, Yanwu Zeng, Mario Chen, Rebecca Dirks, Martin Sirengo, Rose Wafula, Kwasi Torpey
Interrupting vertical transmission of HIV from mothers to infants provides opportunity to transform the HIV/AIDS epidemic by eliminating new infections among children. We estimate mother-to-child transmission rates of infants born to known HIV-positive mothers offered prevention of mother-to-child transmission interventions and provide an indication of Kenya's progress toward elimination of perinatal transmission. We obtained from the Kenya National Early Infant Diagnosis (EID) database, all 131,451 DNA polymerase chain reaction test results of HIV-exposed infants aged 0-18 months who had dried blood spot samples taken between January 2008 and October 2013...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28797019/associations-of-low-vitamin-d-and-elevated-parathyroid-hormone-concentrations-with-bone-mineral-density-in-perinatally-hiv-infected-children
#11
Denise L Jacobson, Charles B Stephensen, Tracie L Miller, Kunjal Patel, Janet S Chen, Russell B Van Dyke, Ayesha Mirza, Gertrud U Schuster, Rohan Hazra, Angela Ellis, Sean S Brummel, Mitchell E Geffner, Margarita Silio, Stephen A Spector, Linda A DiMeglio
BACKGROUND: Perinatally HIV-infected (PHIV) children have, on average, lower bone mineral density (BMD) than perinatally HIV-exposed uninfected (PHEU) and healthy children. Low 25-hydroxy vitamin D [25(OH)D] and elevated parathyroid hormone (PTH) concentrations may lead to suboptimal bone accrual. METHODS: PHIV and PHEU children in the Pediatric HIV/AIDS Cohort Study had total body (TB) and lumbar spine (LS) BMD and bone mineral content (BMC) measured by dual-energy x-ray absorptiometry; BMD z-scores (BMDz) were calculated for age and sex...
September 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28796679/delivery-after-40-weeks-of-gestation-in-pregnant-women-with-well-controlled-human-immunodeficiency-virus
#12
Rachel K Scott, Nahida Chakhtoura, Margaret M Burke, Rachel A Cohen, Regis Kreitchmann
OBJECTIVE: To evaluate whether there is increased mother-to-child transmission of human immunodeficiency virus (HIV)-1 associated with deliveries at 40 weeks of estimated gestational age (EGA) or greater in pregnant women with HIV-1 viral loads of 1,000 copies/mL or less. METHODS: We performed a secondary analysis of the Eunice Kennedy Shriver National Institute of Child Health and Human Development International Site Development Initiative Perinatal and Longitudinal Study in Latin American Countries and International Maternal Pediatric Adolescent AIDS Clinical Trials P1025 cohorts...
September 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28796673/human-immunodeficiency-virus-viral-load-rebound-near-delivery-in-previously-suppressed-combination-antiretroviral-therapy-treated-pregnant-women
#13
Isabelle Boucoiran, Arianne Y K Albert, Karen Tulloch, Emily C Wagner, Neora Pick, Julie van Schalkwyk, P Richard Harrigan, Deborah Money
OBJECTIVE: To assess the stability of human immunodeficiency virus (HIV) viral load suppression within 1 month before birth in pregnant women receiving antenatal combination antiretroviral therapy (CART). METHODS: This is a retrospective cohort study of a Canadian provincial perinatal HIV database from 1997 to 2015. Inclusion criteria were live birth and CART received for at least 4 weeks. Viral load rebound, defined as viral load greater than 50 copies/mL (or greater than 400 copies/mL for 1997-1998) and measured within 1 month before delivery, was identified in women who had at least one previous undetectable viral load during pregnancy...
September 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28796670/turning-the-page-on-perinatal-human-immunodeficiency-virus
#14
Jeffrey Stringer
No abstract text is available yet for this article.
September 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28782457/prospective-memory-in-youth-with-perinatally-acquired-hiv-infection
#15
Lynnette L Harris, Miriam C Chernoff, Sharon L Nichols, Paige L Williams, Patricia A Garvie, Cenk Yildirim, Stephen R McCauley, Steven Paul Woods
Youth with perinatal HIV infection (PHIV) are at increased risk for neurocognitive impairment (NCI). Prospective memory (PM) is a complex neurocognitive function that has been shown to be impaired in adults with HIV disease and independently associated with poorer daily living skills, including medication nonadherence. The current study sought to determine the presence and extent of PM deficits in youth with PHIV. Participants included 173 youth with PHIV and 85 youth perinatally HIV-exposed but uninfected (PHEU), mean age 14...
August 7, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28776463/prevalence-and-impact-of-sexually-transmitted-infections-in-pregnant-women-in-central-ethiopia
#16
Andreas Schönfeld, Torsten Feldt, Tafese B Tufa, Hans M Orth, André Fuchs, Million G Mesfun, Frieder Pfäfflin, Tamara Nordmann, Matthias Breuer, Monika Hampl, Dieter Häussinger
Human immunodeficiency virus (HIV) continues to be a major global public health issue and omnipresent sexually transmitted infections (STIs) increase the risk of HIV acquisition. Moreover, STIs and HIV in pregnant women can harm the unborn child. In this study, we systematically investigated the prevalence of HIV, relevant STIs and vaginal group B streptococcus colonization among pregnant women presenting at Asella Teaching Hospital in central Ethiopia and their effect on perinatal mortality. A follow-up was performed six weeks after delivery...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28758023/strategies-to-improve-the-uptake-of-effective-contraception-in-perinatally-hiv-infected-adolescents
#17
EDITORIAL
Nadia Kancheva Landolt, Jullapong Achalapong, Pope Kosalaraksa, Witaya Petdachai, Chaiwat Ngampiyaskul, Stephen Kerr, Pongrak Boonyanurak, Jintanat Ananworanich, Torsak Bunupuradah
OBJECTIVE: To assess strategies to improve safe-sex practices in sexually active female adolescents living with HIV, through linking reproductive health (RH) care with HIV care. METHODS: A single arm, 48-week prospective study was conducted with 77 sexually active adolescents in five sites in Thailand. Guided RH education was carried out through video, brochures and individual counselling. Participants were offered free effective contraception (EC), in addition to a barrier method (dual contraception) versus barrier method only...
July 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28751827/hiv-is-always-with-me-men-living-with-perinatally-acquired-hiv-and-planning-their-families
#18
Marisa Echenique, Rachel S Bookman, Violeta J Rodriguez, Richard P LaCabe, JoNell Efantis Potter, Deborah L Jones
Once expected to not survive childhood, youth with perinatally-acquired HIV have now reached young adulthood are of reproductive age and sexually active. Given the health impact of pregnancy among YPHIV, understanding reproductive decision making may inform preconception counseling strategies. Most literature regarding reproductive health among YPHIV focuses on women, overlooking one of the most important factors influencing the reproductive decision making process, male sexual partners. This manuscript examined attitudes, perceptions and experiences of young men with perinatally-acquired HIV (YMPHIV) regarding family planning and relationships, safer sex, disclosure, stigma and psychological health...
2017: Open Access J Contracept
https://www.readbyqxmd.com/read/28747410/a-systematic-review-and-meta-analysis-of-studies-evaluating-the-performance-and-operational-characteristics-of-dual-point-of-care-tests-for-hiv-and-syphilis
#19
REVIEW
Harriet D Gliddon, Rosanna W Peeling, Mary L Kamb, Igor Toskin, Teodora E Wi, Melanie M Taylor
BACKGROUND: Mother-to-child transmission (MTCT) of syphilis and HIV continue to be important yet preventable causes of perinatal and infant morbidity and mortality. OBJECTIVES: To systematically review, critically appraise and perform a meta-analysis to evaluate the operational characteristics of dual rapid diagnostic tests (RDTs) for HIV/syphilis and evaluate whether they are cost effective, acceptable and easy to use. DESIGN: Systematic review and meta-analysis...
July 26, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28746260/perinatal-hiv-infection-and-exposure-and-their-association-with-dental-caries-in-nigerian-children
#20
Modupe Coker, Samer El-Kamary, Cyril Enwonwu, William Blattner, Patricia Langenberg, Emmanuel Mongodin, Paul Akhigbe, Ozo Obuekwe, Austin Omoigberale, Manhattan Charurat
BACKGROUND: Although HIV infection is associated with well-known oral pathologies, there remains a dearth of comparative studies aimed at determining the association between HIV infection/exposure and early childhood caries. METHODS: This is a cross-sectional study using a convenience sample of 3 groups of children receiving care at a tertiary care hospital in Nigeria. The groups include HIV infected (HI); HIV exposed but uninfected (HEU); and HIV unexposed and uninfected (HUU) children aged 6 through 72 months...
July 19, 2017: Pediatric Infectious Disease Journal
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