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https://www.readbyqxmd.com/read/28525203/-short-history-of-cranial-trauma-in-western-country-part-2
#1
J Noterman
The treatment of cranial traumatism has been the subject of numerous publications since the " corpus hippocraticum ". Following this period, the school of Alexandria will only be known thanks to Celsus. After him, Galen will determine the therapeutic attitude in accordance with the hippocratic theory. This theory will have an influence for more than 1.500 years. A better knowledge of anatomy will shake the galenic system for the first time at the Renaissance. The decisive progress will arise in the XIX century, with the emergence of experimental medicine, Pasteur's discoveries, and the greater knowledge of nervous system function...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28510565/electric-renaissance
#2
Annie Sneed
No abstract text is available yet for this article.
May 16, 2017: Scientific American
https://www.readbyqxmd.com/read/28509773/perioperative-management-of-antithrombotic-therapies
#3
Timur Yurttas, Patrick M Wanner, Miodrag Filipovic
PURPOSE OF REVIEW: Perioperative coagulation management is becoming increasingly frequent in the daily routine of the anesthesiologist and with the plethora of new substances on the market also increasingly complex. The perioperative setting poses unique challenges requiring an individualized evaluation and management of antithrombotic therapy. This review shall summarize the newest developments in this domain. RECENT FINDINGS: New data in patients with atrial fibrillation have led to a paradigm change in the perioperative management of antithrombotics...
May 15, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28491148/moving-beyond-vascular-endothelial-growth-factor-targeted-therapy-in-renal-cell-cancer-latest-evidence-and-therapeutic-implications
#4
REVIEW
Che-Kai Tsao, Bobby Liaw, Catherine He, Matthew D Galsky, John Sfakianos, William K Oh
Renal cell cancer (RCC) continues to be among the most lethal malignancies in the USA. Introduction of anti-vascular epidermal growth factor receptor tyrosine kinase inhibitors over a decade ago resulted in improvement in disease outcomes, but further development of new therapies largely stagnated for many years. More recently, a better understanding of disease biology and treatment-resistance patterns has led to a second renaissance in drug development, with the anti-programmed cell death protein 1 immune checkpoint inhibitor, nivolumab, paving the way for additional therapies entering clinical trial testing in the treatment of RCC...
April 2017: Therapeutic Advances in Medical Oncology
https://www.readbyqxmd.com/read/28478672/colloidal-particles-at-a-range-of-fluid-fluid-interfaces
#5
Bernard P Binks
The study of solid particles residing at fluid-fluid interfaces has become an established area in surface and colloid science recently, experiencing a renaissance since around 2000. Particles at interfaces arise in many industrial products and processes such as antifoam formulations, crude oil emulsions, aerated foodstuffs, and flotation. Although they act in many ways like traditional surfactant molecules, they offer distinct advantages also, and the area is now multidisciplinary, involving research in the fundamental science and potential applications...
May 6, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28469009/heroes-of-the-engram
#6
Sheena A Josselyn, Stefan Köhler, Paul W Frankland
In 1904, Richard Semon introduced the term "engram" to describe the neural substrate responsible for (or at least important in) storing and recalling memories (i.e., a memory trace). The recent introduction of a vast array of powerful new tools to probe and manipulate memory function at the cell and neuronal circuit level has spurred an explosion of interest in studying the engram. However, the present "engram renaissance" was not borne in isolation but rather builds on a long tradition of memory research. We believe it is important to acknowledge the debts our current generation of scientists owes to those scientists who have offered key ideas, persevered through failed experiments and made important discoveries before us...
May 3, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28468989/citron-kinase-renaissance-of-a-neglected-mitotic-kinase
#7
REVIEW
Pier Paolo D'Avino
Cell division controls the faithful segregation of genomic and cytoplasmic materials between the two nascent daughter cells. Members of the Aurora, Polo and cyclin-dependent (Cdk) kinase families are known to regulate multiple events throughout cell division, whereas another kinase, citron kinase (CIT-K), for a long time has been considered to function solely during cytokinesis, the last phase of cell division. CIT-K was originally proposed to regulate the ingression of the cleavage furrow that forms at the equatorial cortex of the dividing cell after chromosome segregation...
May 3, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28463624/evaluation-of-robot-guided-minimally-invasive-implantation-of-2067-pedicle-screws
#8
Naureen Keric, Christian Doenitz, Amer Haj, Izabela Rachwal-Czyzewicz, Mirjam Renovanz, Dominik M A Wesp, Stephan Boor, Jens Conrad, Alexander Brawanski, Alf Giese, Sven R Kantelhardt
Objective Recent studies have investigated the role of spinal image guidance for pedicle screw placement. Many authors have observed an elevated placement accuracy and overall improvement of outcome measures. This study assessed a bi-institutional experience following introduction of the Renaissance miniature robot for spinal image guidance in Europe. Methods The medical records and radiographs of all patients who underwent robot-guided implantation of spinal instrumentation using the novel system (between October 2011 and March 2015 in Mainz and February 2014 and February 2016 in Regensburg) were reviewed to determine the efficacy and safety of the newly introduced robotic system...
May 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28463609/initial-academic-experience-and-learning-curve-with-robotic-spine-instrumentation
#9
Timur M Urakov, Ken Hsuan-Kan Chang, S Shelby Burks, Michael Y Wang
OBJECTIVE Spine surgery is complex and involves various steps. Current robotic technology is mostly aimed at assisting with pedicle screw insertion. This report evaluates the feasibility of robot-assisted pedicle instrumentation in an academic environment with the involvement of residents and fellows. METHODS The Renaissance Guidance System was used to plan and execute pedicle screw placement in open and percutaneous consecutive cases performed in the period of December 2015 to December 2016. The database was reviewed to assess the usability of the robot by neurosurgical trainees...
May 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28447124/history-of-clubfoot-treatment-part-i-from-manipulation-in-antiquity-to-splint-and-plaster-in-renaissance-before-tenotomy
#10
Philippe Hernigou, Maxime Huys, Jacques Pariat, Sibylle Jammal
Idiopathic clubfoot is one of the most common problems in paediatric orthopaedics. The treatment is controversial and continues to be one of the challenges in paediatric orthopaedics. The aim of this review is to assess the different methods of clubfoot treatment used over the years in light of the documentation present in the literature and art paintings from the antiquity to the end of the 19th century. The aim of this paper is to review all treatment methods of the clubfoot over the years that were proposed to provide patients a functional, pain-free, normal-looking foot, with good mobility, without calluses, and requiring no special shoes...
April 26, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28446058/success-and-suppression-arabic-sciences-and-philosophy-in-the-renaissance
#11
Maryam M Patton
No abstract text is available yet for this article.
April 27, 2017: Annals of Science
https://www.readbyqxmd.com/read/28445055/molecular-mechanism-of-overhauser-dynamic-nuclear-polarization-in-insulating-solids
#12
Svetlana Pylaeva, Konstantin L Ivanov, Marc Baldus, Daniel Sebastiani, Hossam Elgabarty
Dynamic nuclear polarization (DNP), a technique that significantly enhances NMR signals, is experiencing a renaissance owing to enormous methodological developments. In the heart of DNP is a polarization transfer mechanism that endows nuclei with much larger electronic spin polarization. Polarization transfer via the Overhauser effect (OE) is traditionally known to be operative only in liquids and conducting solids. Very recently, surprisingly strong OE-DNP in insulating solids has been reported, with a DNP efficiency that increases with the magnetic field strength...
April 28, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28443838/charge-detection-mass-spectrometry-weighing-heavier-things
#13
REVIEW
David Z Keifer, Elizabeth E Pierson, Martin F Jarrold
Charge detection mass spectrometry (CDMS) is a single molecule method where the mass of each ion is directly determined from individual measurements of its mass-to-charge ratio and charge. CDMS is particularly valuable for the analysis of high mass and heterogeneous analytes, where conventional MS methods are often confounded. In the last few years, CDMS has received a renaissance. Technical developments have improved the resolution and dramatically increased the breadth of problems that can be addressed. These improvements have moved CDMS more into the mainstream as interest in the application of mass spectrometry to high molecular weight species has grown...
April 26, 2017: Analyst
https://www.readbyqxmd.com/read/28443099/a-century-of-radiation-therapy-and-adaptive-immunity
#14
REVIEW
Dörthe Schaue
The coming of age for immunotherapy (IT) as a genuine treatment option for cancer patients through the development of new and effective agents, in particular immune checkpoint inhibitors, has led to a huge renaissance of an old idea, namely to harness the power of the immune system to that of radiation therapy (RT). It is not an overstatement to say that the combination of RT with IT has provided a new conceptual platform that has re-energized the field of radiation oncology as a whole. One only has to look at the immense rise in sessions at professional conferences and in grant applications dealing with this topic to see its emergence as a force, while the number of published reviews on the topic is staggering...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28440654/holocene-atmospheric-mercury-levels-reconstructed-from-peat-bog-mercury-stable-isotopes
#15
Maxime Enrico, Gaël Le Roux, Lars-Eric Heimbürger, Pieter Van Beek, Marc Souhaut, Jérome Chmeleff, Jeroen E Sonke
Environmental regulations on mercury (Hg) emissions and associated ecosystem restoration are closely linked to what Hg levels we consider natural. It is widely accepted that atmospheric Hg deposition has increased by a factor 3 ± 1 since preindustrial times. However, no long-term historical records of actual atmospheric gaseous elemental Hg (GEM) concentrations exist. In this study we report Hg stable isotope signatures in Pyrenean peat records (southwestern Europe) that are used as tracers of Hg deposition pathway (Δ(200)Hg, wet vs dry Hg deposition) and atmospheric Hg sources and cycling (δ(202)Hg, Δ(199)Hg)...
May 9, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28440233/-clinical-cytology-for-endoscopists-a-practical-guide
#16
REVIEW
Michael Hocke, Theodoros Topalidis, Barbara Braden, Christoph F Dietrich
Clinical cytology was originally used by clinicians to provide rapid diagnosis. However, with advancing medical subspecialization, few clinicians interpret cytology themselves these days, for example, gynecologists, hematologists, urologists, and occasional gastroenterologist (mainly in Asian countries). Cytological assessment enjoyed a renaissance with the development of endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA). Subsequently, pathologists, most of them more experienced in histology, had to take over...
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28439378/oman-vision-2050-for-health-research-a-strategic-plan-for-the-future-based-on-the-past-and-present-experience
#17
REVIEW
Adhra Hilal Nasser Al Mawali, Ahmed Mohamed Al Qasmi, Sultana Mohamed Saif Al Sabahi, John Idikula, Mahmoud Attia Abd Elaty, Magdi Morsi, Ali Talib Al Hinai
Health care delivery in Oman has attained great heights since the modern renaissance in 1970. Although the health service had the main impetus all these years, the importance of health research began to take place by mid 1990's and is now gaining momentum as an important responsibility and activity of the Ministry of Health (MoH). Although there has been progressively increasing investment and commitment to research activities in the recent Five Year Plan for Health Development, it still lags behind in the quality and quantity of research output...
March 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28438398/triglycerides-a-reappraisal
#18
REVIEW
Philipp Wiesner, Karol E Watson
Elevated cholesterol levels are clearly independently associated with adverse cardiovascular events. Another class of lipid particles, triglycerides, is also abundant in the human body and has been found in atherosclerotic plaques. Recent observational studies have demonstrated an association between elevated triglyceride levels and increased risk for future cardiovascular events. With this knowledge and the discovery of effective agents to lower triglyceride levels, the management of triglycerides is currently undergoing a renaissance...
March 21, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28437132/home-enteral-nutrition-updates-trends-and-challenges
#19
Karen Martin, Gabriela Gardner
The true prevalence of home enteral nutrition (HEN) utilization is unclear and requires further study. HEN therapy has remained virtually unchanged for several decades. However, new trends in HEN are evolving; enteral nutrition is undergoing changes ranging from enteral feeding devices, ingredients used, practice innovations, and challenges with reimbursement. A 2006 Joint Commission call to action that reported 2 sentinel events related to misconnections set things into motion for the transition of enteral device connectors to become specific for enteral nutrition use, which will affect patients who receive HEN...
April 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28429066/atmospheric-pressure-maldi-for-the-noninvasive-characterization-of-carbonaceous-ink-from-renaissance-documents
#20
Giuseppe Grasso, Marzia Calcagno, Alessandro Rapisarda, Roberta D'Agata, Giuseppe Spoto
The analytical methods that are usually applied to determine the compositions of inks from ancient manuscripts usually focus on inorganic components, as in the case of iron gall ink. In this work, we describe the use of atmospheric pressure/matrix-assisted laser desorption ionization-mass spectrometry (AP/MALDI-MS) as a spatially resolved analytical technique for the study of the organic carbonaceous components of inks used in handwritten parts of ancient books for the first time. Large polycyclic aromatic hydrocarbons (L-PAH) were identified in situ in the ink of XVII century handwritten documents...
April 21, 2017: Analytical and Bioanalytical Chemistry
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