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https://www.readbyqxmd.com/read/28099339/pedicle-screw-placement-accuracy-of-bone-mounted-miniature-robot-system
#1
Tai-Hsin Tsai, Rong-Dar Tzou, Yu-Feng Su, Chieh-Hsin Wu, Cheng-Yu Tsai, Chih-Lung Lin
This article describes factors affecting the accuracy of transpedicle screw placements performed with the Renaissance robot-guided system and reviews the relevant literature. Between January 2013 and January 2015, Renaissance robot-guided spinal surgery was performed in 125 patients at Kaohsiung Medical University Hospital in Kaohsiung, Taiwan. The surgeries included 662 transpedicle screw implants and 49 Kirschner wire (K-wire) reimplants performed by intraoperative repositioning. The lead author evaluated the accuracy of all K-wire insertions and classified their accuracy into 3 categories relative to the preoperative plan for transpedicle screw placement...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28062715/molecular-imaging-and-therapy-with-a-purpose-a-renaissance-of-nuclear-medicine
#2
EDITORIAL
Johannes Czernin
No abstract text is available yet for this article.
January 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28062532/lipid-synthesis-is-a-metabolic-liability-of-non-small-cell-lung-cancer
#3
Robert U Svensson, Reuben J Shaw
The renaissance in the study of cancer metabolism has refocused efforts to identify and target metabolic dependencies of tumors as an approach for cancer therapy. One of the unique metabolic requirements that cancer cells possess to sustain their biosynthetic growth demands is altered fatty acid metabolism, in particular the synthesis of de novo fatty acids that are required as cellular building blocks to support cell division. Enhanced fatty acid synthesis that is observed in many tumor types has been postulated to open a therapeutic window for cancer therapy and, correspondingly, efforts to pharmacologically inhibit key enzymes of fatty acid synthesis are being pursued...
January 6, 2017: Cold Spring Harbor Symposia on Quantitative Biology
https://www.readbyqxmd.com/read/28059802/recent-progress-in-translational-research-on-neurovascular-and-neurodegenerative-disorders
#4
Hans-Ulrich Demuth, Rick M Dijkhuizen, Tracy D Farr, Mathias Gelderblom, Karen Horsburgh, Costantino Iadecola, Damian D Mcleod, Dominik Michalski, Tim H Murphy, Josune Orbe, Willem M Otte, Gabor C Petzold, Nikolaus Plesnila, Georg Reiser, Klaus G Reymann, Maria A Rueger, Dorothee Saur, Sean I Savitz, Stephan Schilling, Neil J Spratt, Renée J Turner, Raghu Vemuganti, Denis Vivien, Manuel Yepes, Marietta Zille, Johannes Boltze
The already established and widely used intravenous application of recombinant tissue plasminogen activator as a re-opening strategy for acute vessel occlusion in ischemic stroke was recently added by mechanical thrombectomy, representing a fundamental progress in evidence-based medicine to improve the patient's outcome. This has been paralleled by a swift increase in our understanding of pathomechanisms underlying many neurovascular diseases and most prevalent forms of dementia. Taken together, these current advances offer the potential to overcome almost two decades of marginally successful translational research on stroke and dementia, thereby spurring the entire field of translational neuroscience...
January 3, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28057368/genomic-translational-research-paving-the-way-to-individualized-cardiac-functional-analyses-and-personalized-cardiology
#5
REVIEW
Ares Pasipoularides
For most of Medicine's past, the best that physicians could do to cope with disease prevention and treatment was based on the expected response of an average patient. Currently, however, a more personalized/precise approach to cardiology and medicine in general is becoming possible, as the cost of sequencing a human genome has declined substantially. As a result, we are witnessing an era of precipitous advances in biomedicine and bourgeoning understanding of the genetic basis of cardiovascular and other diseases, reminiscent of the resurgence of innovations in physico-mathematical sciences and biology-anatomy-cardiology in the Renaissance, a parallel time of radical change and reformation of medical knowledge, education and practice...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28057260/a-renaissance-in-nepovirus-research-provides-new-insights-into-their-molecular-interface-with-hosts-and-vectors
#6
REVIEW
M Fuchs, C Schmitt-Keichinger, H Sanfaçon
Nepoviruses supplied seminal landmarks to the historical trail of plant virology. Among the first agriculturally relevant viruses recognized in the late 1920s and among the first plant viruses officially classified in the early 1970s, nepoviruses also comprise the first species for which a soil-borne ectoparasitic nematode vector was identified. Early research on nepoviruses shed light on the genome structure and expression, biological properties of the two genomic RNAs, and mode of transmission. In recent years, research on nepoviruses enjoyed an extraordinary renaissance...
2017: Advances in Virus Research
https://www.readbyqxmd.com/read/28043756/-a-renaissance-man-and-an-enlightenment-thinker-in-21st-century-in-the-ninetieth-birthday-of-alfredo-de-micheli
#7
Raúl Izaguirre Ávila
No abstract text is available yet for this article.
January 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28041633/back-to-the-basics-cnidarians-start-to-fire
#8
REVIEW
Thomas C G Bosch, Alexander Klimovich, Tomislav Domazet-Lošo, Stefan Gründer, Thomas W Holstein, Gáspár Jékely, David J Miller, Andrea P Murillo-Rincon, Fabian Rentzsch, Gemma S Richards, Katja Schröder, Ulrich Technau, Rafael Yuste
The nervous systems of cnidarians, pre-bilaterian animals that diverged close to the base of the metazoan radiation, are structurally simple and thus have great potential to reveal fundamental principles of neural circuits. Unfortunately, cnidarians have thus far been relatively intractable to electrophysiological and genetic techniques and consequently have been largely passed over by neurobiologists. However, recent advances in molecular and imaging methods are fueling a renaissance of interest in and research into cnidarians nervous systems...
December 29, 2016: Trends in Neurosciences
https://www.readbyqxmd.com/read/28030554/procedures-and-frequencies-of-embalming-and-heart-extractions-in-modern-period-in-brittany-contribution-to-the-evolution-of-ritual-funerary-in-europe
#9
Rozenn Colleter, Fabrice Dedouit, Sylvie Duchesne, Fatima-Zohra Mokrane, Véronique Gendrot, Patrice Gérard, Henri Dabernat, Éric Crubézy, Norbert Telmon
The evolution of funeral practices from the Middle Ages through the Modern era in Europe is generally seen as a process of secularization. The study, through imaging and autopsy, of two mummies, five lead urns containing hearts, and more than six hundred skeletons of nobles and clergymen from a Renaissance convent in Brittany has led us to reject this view. In addition to exceptional embalming, we observed instances in which hearts alone had been extracted, a phenomenon that had never before been described, and brains alone as well, and instances in which each spouse's heart had been placed on the other's coffin...
2016: PloS One
https://www.readbyqxmd.com/read/28018856/time-and-circumstances-cancer-cell-metabolism-at-various-stages-of-disease-progression
#10
REVIEW
Georg F Weber
Over the past decade, research into the unique ways, in which cancer cells skew their metabolism, has had a renaissance-for the repeated time over more than 80 years since the discovery of an inherent preference for glycolysis. Importantly, the Warburg effect that arises in primary neoplasms is not the sole prominent metabolic phenomenon. Once the transformed cells are shed from their initial growth and begin the process of metastasis, their energy requirements change and they adapt to the increased demand for adenosine triphosphate, which if not satisfied would lead to anoikis...
2016: Frontiers in Oncology
https://www.readbyqxmd.com/read/28010520/innovation-urgency-and-acceptance-at-the-9th-vaccine-renaissance
#11
Anne S De Groot, Lenny Moise
No abstract text is available yet for this article.
December 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28005119/an-overview-of-the-history-of-orthopedic-surgery
#12
Ishaan Swarup, Joseph F O'Donnell
Orthopedic surgery has a long and rich history. While the modern term orthopedics was coined in the 1700s, orthopedic principles were beginning to be developed and used during primitive times. The Egyptians continued these practices, and described ways to recognize and manage common orthopedic conditions. The Greeks and Romans subsequently began to study medicine in a systematic manner, and greatly improved our understanding of orthopedic anatomy and surgical technique. After a period of little progress during the Middle Ages, rapid advancement was noted during the Renaissance, including the description of various injuries, improvements in surgical technique, and development of orthopedic hospitals...
November 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27989678/introduction-a-new-renaissance-in-pericardial-diseases
#13
EDITORIAL
Craig R Asher, Allan L Klein
No abstract text is available yet for this article.
December 15, 2016: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/27987145/nucleoside-modified-mrna-vaccines-for-infectious-diseases
#14
Norbert Pardi, Drew Weissman
In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune responses against pathogens, making it a viable new platform for vaccine development (reviewed in Weissman, Expert Rev Vaccines 14:265-281, 2015; Sahin et al., Nat Rev Drug Discov 13:759-780, 2014). The incorporation of modified nucleosides in mRNA has many advantages and is currently undergoing a renaissance in the field of therapeutic protein delivery. Its use in a vaccine against infectious diseases has only begun to be described, but offers advantages for the generation of potent and long-lived antibody responses...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27974364/a-christmas-renaissance
#15
S Dholakia, P J Friend, L Maguire
No abstract text is available yet for this article.
December 14, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27941809/engineering-dissipation-with-phononic-spectral-hole-burning
#16
R O Behunin, P Kharel, W H Renninger, P T Rakich
Optomechanics, nano-electromechanics, and integrated photonics have brought about a renaissance in phononic device physics and technology. Central to this advance are devices and materials supporting ultra-long-lived photonic and phononic excitations that enable novel regimes of classical and quantum dynamics based on tailorable photon-phonon coupling. Silica-based devices have been at the forefront of such innovations for their ability to support optical excitations persisting for nearly 1 billion cycles, and for their low optical nonlinearity...
December 12, 2016: Nature Materials
https://www.readbyqxmd.com/read/27939460/exploring-the-brain-skin-connection-leads-and-lessons-from-the-hair-follicle
#17
R Paus
Research into how the central nervous system (CNS) and the skin of mammals are physiologically connected and how this "brain-skin connection" may be therapeutically targeted in clinical medicine has witnessed a renaissance. A key element in this development has been the discovery that mammalian skin and its appendages, namely human scalp hair follicles (HFs), not only are important, long-underestimated target tissues for classical neurohormones, neurotrophins and neuropeptides, but also are eminent peripheral tissue sources for the production and/or release of these neuromediators...
October 2016: Current Research in Translational Medicine
https://www.readbyqxmd.com/read/27928894/the-renaissance-of-life-near-the-boiling-point-at-last-genetics-and-metabolic-engineering
#18
Michael W W Adams, Robert M Kelly
We discuss here the prospects for biotechnology of extreme thermophilic microorganisms.
December 8, 2016: Microbial Biotechnology
https://www.readbyqxmd.com/read/27916502/renaissance-of-isoprenoids-research
#19
EDITORIAL
Vladimir A Khripach, Pavel B Drašar
No abstract text is available yet for this article.
January 2017: Steroids
https://www.readbyqxmd.com/read/27916188/editorial-commentary-renaissance-of-primary-anterior-cruciate-ligament-repair-is-history-repeating-itself
#20
EDITORIAL
Erik Hohmann
In a comparative Level III study, Achtnich et al. compared suture anchor repair of acute proximal anterior cruciate ligament avulsion tears with single-bundle anterior cruciate ligament reconstruction with the quadrupled semitendinosus tendon. Short-term follow-up at a mean of 28 months showed that the between-group differences were not different. These results are encouraging but not different from other published series 25+ years ago. Only time will tell whether the long-term outcomes are identical and whether these techniques will also die a slow death...
December 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
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