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https://www.readbyqxmd.com/read/28090053/a-suspected-case-of-an-alveolar-haemorrhage-caused-by-dasatinib
#1
Yoritake Sakoda, Yojiro Arimori, Masakatsu Ueno, Takafumi Matsumoto
A 39-year-old man treated with dasatinib for chronic myelogenous leukaemia presented to our hospital with haemoptysis, coughing, and dyspnoea. Chest radiography and computed tomography revealed ground-glass opacities and a crazy-paving pattern. Bronchoalveolar lavage was not performed due to serious hypoxemia and bleeding. Significant bleeding from the peripheral bronchi led to a diagnosis of an alveolar haemorrhage. Dasatinib-induced alveolar haemorrhaging was suspected based on the clinical findings. His condition improved immediately after dasatinib withdrawal and initiation of steroid therapy...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28078876/comparative-molecular-analysis-of-bacterial-species-associated-with-periodontal-disease
#2
V De Iuliis, S Ursi, L M Di Tommaso, M Caruso, A Marino, S D Ercole, S Caputi, B Sinjari, F Festa, M Macri, S Martinotti, G Vitullo, E Toniato
Periodontal disease is an inflammatory disorder affecting the supporting teeth structures, including gingiva, periodontal ligament and alveolar bone, causing loss of connective tissue, reabsorption of alveolar bone and formation of periodontal pockets. The aim of this study is to find a correlation between bacterial growth and periodontal disease. Fifty-seven patients aged between 21 and 65 years, median age 46 years, were enrolled. According to gingival pocket depth, ranging from 3 to 7 mm, patients were divided into two groups: the first (30 patients, 53%) with deep pockets ³ 5 mm and the second (27 patients, 47%) less than 5 mm...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28072959/-diagnosis-of-pulmonary-hemorrhage-of-the-newborn-infants-using-lung-ultrasonography
#3
J Liu, W Fu, S W Chen, Y Wang
Objective: To investigate the accuracy and reliability of lung ultrasound in diagnosis of pulmonary hemorrhage of the newborn infants. Method: From January 2014 to May 2016, 142 neonates from the Army General Hospital of the Chinese PLA were enrolled in the study. They were divided into two groups: a study group of 42 neonates, who were diagnosed with pulmonary hemorrhage according to their medical history, clinical manifestations and chest X-ray findings, and a control group of 100 neonates with no lung disease...
January 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28067755/vascular-structures-of-the-lateral-wall-of-the-maxillary-sinus-a-vascular-labeling-technique
#4
José Caraballo, Alba Gálvez, María Cristina Manzanares-Céspedes, Iván Valdivia-Gandur, Rui Figueiredo, Eduard Valmaseda-Castellón
PURPOSE: Sinus floor augmentation is a common procedure in implant dentistry. However, several intraoperative complications can occur during this procedure, such as bleeding from the lateral wall of the maxillary sinus. The aim of this study was to describe the vascular structures of the lateral wall of the maxillary sinus using a vascular labeling technique. MATERIALS AND METHODS: Ten cadaveric specimens were prepared by the vascular labeling technique. Liquid latex was injected into the large vessels of the head, and the lateral wall of the maxillary sinus was exposed by dissection...
January 6, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28025476/a-case-of-hepatocellular-carcinoma-presenting-as-a-gingival-mass
#5
Min Jung Kwon, Soo Hyung Ryu, Soo Yeon Jo, Chul Hoon Kwak, Won Jae Yoon, Jeong Seop Moon, Hye Kyung Lee
Oral metastatic tumor, which is uncommon and represents less than 1% of malignant oral neoplasms, usually arises from a primary mucosal or cutaneous cancer located in the head and neck regions. Metastasis of hepatocellular carcinoma (HCC) to the oral cavity, especially to gingiva, is extremely rare. A 50-year-old man, who was a chronic alcoholic and hepatitis B virus carrier, presented with abdominal distension and weight loss for the past 3 months. Three-phased contrast-enhanced abdominal CT revealed numerous conglomerated masses in the liver, suggesting huge HCCs arising in the background of liver cirrhosis with a large amount of ascites...
December 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/27872767/diffuse-alveolar-hemorrhage-associated-with-edoxaban-therapy
#6
Kenichi Nitta, Hiroshi Imamura, Akihiro Yashio, Satoko Kashima, Katsunori Mochizuki
Introduction. The main adverse effect of anticoagulant therapy is bleeding, and major bleeding, including intracranial, gastrointestinal, and retroperitoneal bleeding, has been reported as an adverse effect of edoxaban, a direct oral anticoagulant (DOAC). Bleeding during systemic anticoagulation with edoxaban presents a therapeutic conundrum, because there is currently no safe or efficacious reversal agent to stop major bleeding. Case Report. A 51-year-old woman had multiple traumatic injuries, including lower limb fractures...
2016: Case Reports in Critical Care
https://www.readbyqxmd.com/read/27860404/perineal-alveolar-soft-part-sarcoma-treated-by-laparoscopy-assisted-total-pelvic-exenteration-combined-with-pubic-resection
#7
Toshisada Aiba, Keisuke Uehara, Satoshi Tsukushi, Yasushi Yoshino, Tomoki Ebata, Yukihiro Yokoyama, Tsuyoshi Igami, Gen Sugawara, Masato Nagino
A 20-year-old woman with a perineal alveolar soft part sarcoma was referred to our hospital. MRI showed that an irregular oval tumor occupied the perineum. The tumor was contiguous to the vagina, rectum, levator muscle, and pubis and was diagnosed as alveolar soft part sarcoma by transvaginal biopsy. Laparoscopy-assisted total pelvic exenteration combined with a pubic resection was performed, and an R0 resection with a wide margin was achieved. It is well known that only R0 resection improves the outcome of patients with localized alveolar soft part sarcoma...
November 10, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27852659/case-of-steven-johnson-syndrome-in-a-male-with-breast-cancer-secondary-to-docetaxel-cyclophosphamide-therapy
#8
Benjamin Jarrett, Sehem Ghazala, Joseph Chao, Sachin Chaudhary
The mortality rate for Stevens-Johnson syndrome (SJS) is estimated to be ∼12% and for toxic epidermal necrolysis (TEN) it is around 30%. It continues to be a severe life-threatening drug reaction. We present a 60-year-old Caucasian man with a medical history significant for breast cancer status post mastectomy and chemotherapy with docetaxel and cyclophosphamide who presented with severe mucositis and a progressing skin rash consistent with SJS. He was started on high-dose corticosteroids and IVIG but continued to have worsening mucosal ulcerations and severe bleeding from the oral, conjunctival and genital mucosa...
November 15, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27833737/the-efficacy-of-supportive-peri-implant-therapies-in-preventing-peri-implantitis-and-implant-loss-a-systematic-review-of-the-literature
#9
REVIEW
Ausra Ramanauskaite, Tellervo Tervonen
OBJECTIVES: To study the efficacy of supportive peri-implant therapies in preventing clinical and radiological signs of peri-implantitis and implant loss. MATERIAL AND METHODS: Longitudinal human studies, published between January 1, 2006, and February 1, 2016, were included based on an electronic search using MEDLINE and EMBASE databases and complemented by a manual search. Articles were included only if 1) they comprised a group of patients involved in/adhering to regular supportive peri-implant therapies (SPTs) and a control group without such therapies or with poor adherence to them, 2) the protocol of the SPTs was clearly described and 3) the outcome was indicated by means of clinical/radiological changes or implant loss...
July 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/27809611/lung-ultrasonography-to-diagnose-pulmonary-hemorrhage-of-the-newborn
#10
Xiao-Ling Ren, Wei Fu, Jing Liu, Ying Liu, Rong-Ming Xia
OBJECTIVES: This study was aimed to investigate the application of lung ultrasound for the diagnosis of Pulmonary hemorrhage of the newborn (PHN). METHODS: From July 2013 to June 2016, 157 neonates were enrolled in the study. They were divided into two groups: a study group of 57 neonates, who were diagnosed with PHN according to their medical history, clinical manifestations and chest X-ray findings, and a control group of 100 neonates with no lung disease.All subjects underwent bedside lung ultrasound in a quiet state in a supine, lateral or prone position, performed by a single expert physician...
November 3, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27807803/choriocarcinoma-syndrome-after-resection-of-primary-pulmonary-choriocarcinoma-report-of-a-case
#11
Tsuyoshi Takahashi, Ryo Kobayashi
BACKGROUND: Choriocarcinoma syndrome is known as a lethal complication from tumoral hemorrhage, which frequently occurs at the site of tumor metastasis. CASE PRESENTATION: A 59-year-old man with 60-pack-year smoking history was referred to our hospital because of hemoptysis. Chest computed tomography (CT) showed a 28 × 18 mm spiculated nodule with a cavity infiltrating the left upper lobe. A transbronchial lung biopsy was performed, and histopathological examinations revealed adenocarcinoma...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27747693/use-of-a-trephine-bur-and-curette-for-minimally-invasive-harvesting-of-particulate-cancellous-bone-and-marrow-from-the-iliac-crest-a-case-of-alveolar-ridge-reconstruction
#12
Yukimori Isoda, Eisaku Imamura, Daisuke Ueno, Tsubasa Akaike, Yoshiki Hamada
Iliac particulate cancellous bone and marrow (PCBM) is still the most predictable autogenous graft material for vertical ridge reconstruction because of its high cell content as well as osteoinductive and osteoconductive properties. However, postoperative meralgia paresthetica, gait disturbance, pain, and bleeding have been reported following conventional harvesting from the anterior iliac crest. We present a case of minimally invasive harvesting of iliac PCBM. A short incision was made, and the iliac crest was exposed after elevation of the periosteal membrane...
December 2016: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/27747649/soft-tissue-grafting-for-peri-implantitis-a-treatment-option-in-case-of-unsuitable-skeletal-basic-morphology-of-the-alveolar-bone-and-lack-of-keratinized-mucosa-a-retrospective-clinical-cohort-study
#13
Michael Stiller, Rainer Mengel, Sebastian Becher, Bernhard Brinkmann, Barbara Peleska, Esther Kluk
BACKGROUND: This retrospective study evaluated soft-tissue grafting as a surgical treatment option for peri-implantitis in case of unsuitable basic skeletal morphology of the alveolar bone and lack of keratinized mucosa. METHODS: Twenty-eight patients (21 females, 7 males, at a mean age 59.4 years) were included with a total of 54 implants. All implants showed peri-implantitis and attached keratinized buccal mucosa of ≤2 mm. A surgical procedure of soft-tissue grafting (STG) was made by inserting an inlay and inlay-onlay transplant...
December 2015: Int J Implant Dent
https://www.readbyqxmd.com/read/27743396/soft-tissue-changes-and-crestal-bone-loss-around-platform-switched-implants-placed-at-crestal-and-subcrestal-levels-36-month-results-from-a-prospective-split-mouth-clinical-trial
#14
Mohammad D Al Amri, Sulieman S Al-Johany, Abdulaziz M Al Baker, Mohammad Q Al Rifaiy, Tariq S Abduljabbar, Abdulaziz A Al-Kheraif
OBJECTIVE: The aim of the present 36-month prospective split-mouth clinical trial was to investigate the peri-implant soft tissue changes and crestal bone loss (CBL) around delayed loaded platform-switched implants placed at crestal and subcrestal levels. MATERIAL AND METHODS: Twenty-three individuals with bilaterally missing either mandibular first or second molars were included. The test and control sites were defined as follows: (i) test sites: implants placed 2 mm below the alveolar crest (subcrestal); (ii) control sites: implants placed at bone level (crestal)...
October 14, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27666673/decrease-of-pericytes-is-associated-with-ligature-induced-periodontitis-liver-disease-in-rats
#15
Daniel Fernando Pereira Vasconcelos, Felipe Rodolfo Pereira da Silva, Moara E Silva Conceição Pinto, Lucas de Araújo Bastos Santana, Ingrid Grazielle Souza, Luan Kelves Miranda de Souza, Natássia Cristina Martins Oliveira, Claudio Angelo Ventura, Pedro Duarte Novaes, André Luiz Dos Reis Barbosa, Jand-Venes Rolim Medeiros, Ivana Mikolasevic, Arya Mani, Jefferson Soares de Oliveira
BACKGROUND: The damages caused by periodontitis have affected not only periodontal tissues, but have also increased the severity of different illnesses such as: rheumatoid arthritis, diabetes and liver diseases. The aim of this study was to investigate the association between induced periodontitis and the damages caused through its systemic effects on the liver. METHODS: Twenty rats were divided into two groups: control and periodontitis. The following parameters were evaluated: Gingival Bleeding Index (GBI), Probing Pocket Depth (PPD), Myeloperoxidase (MPO) activity, Alveolar Bone Loss (ABL) for periodontal tissues; histopathological examination of gingival and liver tissues; immunohistochemistry to positive cell for neural/glial antigen 2 (NG2) expressed in hepatic pericytes, glutathione (GSH) and malondialdehyde (MDA) concentrations in liver; serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST)...
September 26, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27660154/transbronchial-cryobiopsy-in-diffuse-parenchymal-lung-disease-retrospective-analysis-of-74-cases
#16
Kamonpun Ussavarungsi, Ryan M Kern, Anja C Roden, Jay H Ryu, Eric S Edell
BACKGROUND: Diagnostic evaluation of patients with diffuse parenchymal lung disease (DPLD) is best achieved by a multidisciplinary team correlating clinical, radiologic, and pathologic features. Surgical lung biopsies remain the gold standard for histopathologic diagnosis of idiopathic interstitial pneumonias. Emerging data suggest an increasing role for transbronchial cryobiopsy (TBC) in DPLD evaluation. We describe our experience with TBC in patients with DPLD. METHODS: We retrospectively reviewed medical records of patients with radiographic features of DPLD who underwent TBC at Mayo Clinic, Rochester, Minnesota in June 2013-September 2015...
September 19, 2016: Chest
https://www.readbyqxmd.com/read/27659183/performance-and-safety-of-collagenated-xenogeneic-bone-block-for-lateral-alveolar-ridge-augmentation-and-staged-implant-placement-a-monocenter-prospective-single-arm-clinical-study
#17
Frank Schwarz, Ilja Mihatovic, Shahram Ghanaati, Jürgen Becker
OBJECTIVES: To assess the clinical safety and performance of collagenated xenogeneic bone block (CXBB) for lateral alveolar ridge augmentation and two-stage implant placement. MATERIAL & METHODS: In ten patients exhibiting a single-tooth gap, the surgical procedure included the preparation of mucoperiosteal flaps, a rigid fixation of CXBB (Geistlich Bio-Graft(®) ) using an osteosynthesis screw, and contour augmentation. After 24 weeks of submerged healing, the primary endpoint was defined as the final ridge width sufficient to place an adequately dimensioned titanium implant at the respective sites...
September 23, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27604635/a-retrospective-analysis-of-14-consecutive-chinese-patients-with-unresectable-or-metastatic-alveolar-soft-part-sarcoma-treated-with-sunitinib
#18
Ting Li, Lei Wang, Huijie Wang, Shujuan Zhang, Atikan Kawuli, Xiaowei Zhang, Zhiguo Luo, Chunmeng Wang
Background The study was aim to assess the efficacy and safety of sunitinib on 14 Chinese patients with locally unresectable or metastatic Alveolar Soft Part Sarcoma (ASPS) at two institutions retrospectively. Methods Patients were treated with 37.5 mg of sunitinib once daily continuously without a scheduled off-treatment period. Dose holds or reductions were recommended for grade 3 AEs but were required for grade 4 AEs. Restarting treatment of sunitinib was allowed when AEs returned back to grade 1 or disappeared...
September 8, 2016: Investigational New Drugs
https://www.readbyqxmd.com/read/27578151/surgical-removal-versus-retention-for-the-management-of-asymptomatic-disease-free-impacted-wisdom-teeth
#19
REVIEW
Hossein Ghaeminia, John Perry, Marloes E L Nienhuijs, Verena Toedtling, Marcia Tummers, Theo J M Hoppenreijs, Wil J M Van der Sanden, Theodorus G Mettes
BACKGROUND: Prophylactic removal of asymptomatic disease-free impacted wisdom teeth is surgical removal of wisdom teeth in the absence of symptoms and with no evidence of local disease. Impacted wisdom teeth may be associated with pathological changes, such as pericoronitis, root resorption, gum and alveolar bone disease (periodontitis), caries and the development of cysts and tumours. When surgical removal is carried out in older people, the risk of postoperative complications, pain and discomfort is increased...
August 31, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27556667/diffuse-alveolar-hemorrhage-in-acute-myeloid-leukemia
#20
Sowmya Nanjappa, Daniel K Jeong, Manjunath Muddaraju, Katherine Jeong, Ebone D Hill, John N Greene
Diffuse alveolar hemorrhage is a potentially fatal pulmonary disease syndrome that affects individuals with hematological and nonhematological malignancies. The range of inciting factors is wide for this syndrome and includes thrombocytopenia, underlying infection, coagulopathy, and the frequent use of anticoagulants, given the high incidence of venous thrombosis in this population. Dyspnea, fever, and cough are commonly presenting symptoms. However, clinical manifestations can be variable. Obvious bleeding (hemoptysis) is not always present and can pose a potential diagnostic challenge...
July 2016: Cancer Control: Journal of the Moffitt Cancer Center
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