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https://www.readbyqxmd.com/read/27913975/clinical-impact-of-an-antibiotic-stewardship-program-at-a-children-s-hospital
#1
Brian R Lee, Jennifer L Goldman, Diana Yu, Angela L Myers, Leslie M Stach, Erin Hedican, Mary Anne Jackson, Jason G Newland
INTRODUCTION: Antibiotic stewardship programs (ASP) improve appropriate antibiotic use. Data are limited on the clinical benefit of ASPs in children's hospitals. This study's objective was to determine the impact of an ASP on length of stay (LOS) and readmission rate among patients admitted to children's hospitals. METHODS: Data from a prospective-audit-with-feedback ASP were used to examine the ASP review characteristics, including antibiotic(s) prescribed, clinical indication, recommendations made by the ASP, and agreement with recommendations...
December 2, 2016: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/27913366/deepr-a-convolutional-net-for-medical-records
#2
Phuoc Nguyen, Truyen Tran, Nilmini Wickramasinghe, Svetha Venkatesh
Feature engineering remains a major bottleneck when creating predictive systems from electronic medical records. At present, an important missing element is detecting predictive regular clinical motifs from irregular episodic records. We present Deepr (short for Deep record), a new end-to-end deep learning system that learns to extract features from medical records and predicts future risk automatically. Deepr transforms a record into a sequence of discrete elements separated by coded time gaps and hospital transfers...
December 1, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27913245/contextual-computing-a-bluetooth-based-approach-for-tracking-healthcare-providers-in-the-emergency-room
#3
Joshua Frisby, Vernon Smith, Stephen Traub, Vimla L Patel
Hospital Emergency Departments (EDs) frequently experience crowding. One of the factors that contributes to this crowding is the "door to doctor time", which is the time from a patient's registration to when the patient is first seen by a physician. This is also one of the Meaningful Use (MU) performance measures that emergency departments report to the Center for Medicare and Medicaid Services (CMS). Current documentation methods for this measure are inaccurate due to the imprecision in manual data collection...
November 29, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/27913082/efficacy-and-feasibility-of-objective-structured-clinical-examination-in-the-internal-assessment-for-surgery-postgraduates
#4
Anitha Muthusami, Subair Mohsina, Sathasivam Sureshkumar, Amaranathan Anandhi, Thirthar Palanivelu Elamurugan, Krishnamachari Srinivasan, Thulasingam Mahalakshmy, Vikram Kate
INTRODUCTION: Traditionally assessment in medical training programs has been through subjective faculty evaluations or multiple choice questions. Conventional examinations provide assessment of the global performance rather than individual competencies thus making the final feedback less meaningful. The objective structured clinical examination (OSCE) is a relatively new multidimensional tool for evaluating training. This study was carried out to determine the efficacy and feasibility of OSCE as a tool for the internal assessment of surgery residents...
November 29, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27912871/short-term-open-label-chamomile-matricaria-chamomilla-l-therapy-of-moderate-to-severe-generalized-anxiety-disorder
#5
John R Keefe, Jun J Mao, Irene Soeller, Qing S Li, Jay D Amsterdam
BACKGROUND: Conventional drug treatments for Generalized Anxiety Disorder (GAD) are often accompanied by substantial side effects, dependence, and/or withdrawal syndrome. A prior controlled study of oral chamomile (Matricaria chamomilla L.) extract showed significant efficacy versus placebo, and suggested that chamomile may have anxiolytic activity for individuals with GAD. HYPOTHESIS: We hypothesized that treatment with chamomile extract would result in a significant reduction in GAD severity ratings, and would be associated with a favorable adverse event and tolerability profile...
December 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27911995/allometry-data-and-equations-for-coastal-marsh-plants
#6
Meng Lu, Joshua S Caplan, Jonathan D Bakker, J Adam Langley, Thomas J Mozdzer, Bert G Drake, J Patrick Megonigal
Coastal marshes are highly valued for ecosystem services such as protecting inland habitats from storms, sequestering carbon, removing nutrients and other pollutants from surface water, and providing habitat for fish, shellfish, and birds. Because plants largely determine the structure and function of coastal marshes, quantifying plant biomass is essential for evaluating these ecosystem services, understanding the biogeochemical processes that regulate ecosystem function, and forecasting tidal wetland responses to accelerated sea level rise...
December 2016: Ecology
https://www.readbyqxmd.com/read/27911489/palliative-care-interventions-in-advanced-dementia
#7
REVIEW
Edel Murphy, Katherine Froggatt, Sheelah Connolly, Eamon O'Shea, Elizabeth L Sampson, Dympna Casey, Declan Devane
BACKGROUND: Dementia is a chronic, progressive and ultimately fatal neurodegenerative disease. Advanced dementia is characterised by profound cognitive impairment, inability to communicate verbally and complete functional dependence. Usual care of people with advanced dementia is not underpinned universally by a palliative approach. Palliative care has focused traditionally on care of people with cancer but for more than a decade, there have been increased calls worldwide to extend palliative care services to include all people with life-limiting illnesses in need of specialist care, including people with dementia...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27911284/different-types-of-exercise-in-multiple-sclerosis-aerobic-exercise-or-pilates-a-single-blind-clinical-study
#8
Bilge Kara, Fadime Küçük, Esra Coşkuner Poyraz, Melda Soysal Tomruk, Egemen İdıman
BACKROUND: The aim of our study is to examine effects of aerobic and Pilates exercises on disability, cognition, physical performance, balance, depression and fatigue in relapsing-remitting Multiple Sclerosis (MS) patients as compared to healthy controls. METHODS: The subjects were divided as aerobic exercise (n = 26), Pilates (n = 9), and the healthy control group (n = 21). We used MSFC, physical performance, Berg balance scale, Beck depression scale, fatique impact scale...
November 25, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27911216/validation-of-antibody-reagents-for-mucin-analysis-in-chronic-inflammatory-airway-diseases
#9
Thorsten Krause, Niels Röckendorf, Karoline I Gaede, Katrin Ramaker, Heike Sinnecker, Andreas Frey
In chronic inflammatory airway diseases, mucins display disease-related alterations in quantity, composition and glycosylation. This opens the possibility to diagnose and monitor inflammatory airway disorders and their exacerbation based on mucin properties. For such an approach to be reasonably versatile and diagnostically meaningful, the mucin of interest must be captured in a reliable, patient-independent way. To identify appropriate mucin-specific reagents, we tested anti-mucin antibodies on mucin-content-standardized, human bronchoalveolar lavage fluid samples in immunoblot assays...
December 2, 2016: MAbs
https://www.readbyqxmd.com/read/27910203/designing-easy-dna-extraction-teaching-creativity-through-laboratory-practice
#10
Endang Susantini, Lisa Lisdiana Isnawati, Aushia Tanzih Al Haq, Guntur Trimulyono
Subject material concerning Deoxyribose Nucleic Acid (DNA) structure in the format of creativity-driven laboratory practice offers meaningful learning experience to the students. Therefore, a laboratory practice in which utilizes simple procedures and easy-safe-affordable household materials should be promoted to students to develop their creativity. This study aimed to examine whether designing and conducting DNA extraction with household materials could foster students' creative thinking. We also described how this laboratory practice affected students' knowledge and views...
December 2, 2016: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/27910189/a-qualitative-investigation-into-the-hiv-disclosure-process-within-an-intimate-partnership-the-moment-i-realized-that-our-relationship-was-developing-into-something-serious-i-just-had-to-tell-him
#11
Charlotte Smith, Rachel Cook, Poul Rohleder
OBJECTIVES: This study sought to elucidate the process through which people living with HIV (PLWH) in the United Kingdom disclose their status to an intimate partner (IP). DESIGN: A qualitative cross-sectional survey design was used. METHOD: A total of 95 PLWH took part. They were presented with a series of open-ended questions enquiring into their last experience of disclosing to an IP. The data were analysed using thematic analysis. RESULTS: Disclosure became a salient issue when the discloser acknowledged their relationship as meaningful...
December 2, 2016: British Journal of Health Psychology
https://www.readbyqxmd.com/read/27910119/the-significance-of-meaningful-and-enjoyable-activities-for-nursing-home-resident-s-experiences-of-dignity
#12
Åshild Slettebø, Berit Saeteren, Synnøve Caspari, Vibeke Lohne, Arne Wilhelm Rehnsfeldt, Anne Kari Tolo Heggestad, Britt Lillestø, Bente Høy, Maj-Britt Råholm, Lillemor Lindwall, Trygve Aasgaard, Dagfinn Nåden
BACKGROUND: Living in a nursing home may be challenging to the residents' experience of dignity. Residents' perception of how their dignity is respected in everyday care is important. AIM: To examine how nursing home residents experience dignity through the provision of activities that foster meaning and joy in their daily life. METHOD: A qualitative design was used and 28 individual semistructured interviews conducted with nursing home residents from six nursing homes in Denmark, Norway and Sweden...
December 2, 2016: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/27910108/a-day-in-the-life-of-a-m%C3%A3-ni%C3%A3-re-s-patient-understanding-the-lived-experiences-and-mental-health-impacts-of-m%C3%A3-ni%C3%A3-re-s-disease
#13
Sarah L Bell, Jessica Tyrrell, Cassandra Phoenix
Concepts of social practice are increasingly being used to understand experiences of everyday life, particularly in relation to consumption and healthy lifestyles. This article builds on this in the context of lives disrupted and reshaped by chronic illness. It uses social practice theory to examine the lived experiences of individuals with Ménière's disease; a long-term progressive vestibular disorder, defined by episodes of severe and debilitating vertigo, aural fullness, tinnitus and sensorineural hearing loss...
December 2, 2016: Sociology of Health & Illness
https://www.readbyqxmd.com/read/27909544/reducing-the-risk-of-stroke-in-patients-with-nonvalvular-atrial-fibrillation-with-direct-oral-anticoagulants-is-one-of-these-not-like-the-others
#14
REVIEW
Paul P Dobesh Pharm D, John Fanikos Mba R Ph
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and increases risk of stroke by nearly 5-fold. While warfarin has been employed successfully to reduce the risk of stroke in these patients, there are a number of challenges with therapy. These include the need for therapeutic monitoring due to variability in patient response, frequent dose adjustments, numerous drug-drug, drug-food, and drug-disease interactions, and a heightened risk of thrombosis and bleeding due to these issues. Current guidelines recommend that the vitamin K antagonists (VKA) or direct oral anticoagulants (DOACs) should be used for thromboprophylaxis in patients with nonvalvular AF at risk for stroke or systemic embolic events...
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909408/reliability-validity-and-usefulness-of-30-15-intermittent-fitness-test-in-female-soccer-players
#15
Nedim Čović, Eldin Jelešković, Haris Alić, Izet Rađo, Erduan Kafedžić, Goran Sporiš, Daniel T McMaster, Zoran Milanović
PURPOSE: The aim of this study was to examine the reliability, validity and usefulness of the 30-15IFT in competitive female soccer players. METHODS: Seventeen elite female soccer players participated in the study. A within subject test-retest study design was utilized to assess the reliability of the 30-15 intermittent fitness test (IFT). Seven days prior to 30-15IFT, subjects performed a continuous aerobic running test (CT) under laboratory conditions to assess the criterion validity of the 30-15IFT. End running velocity (VCT and VIFT), peak heart rate (HRpeak) and maximal oxygen consumption (VO2max) were collected and/or estimated for both tests...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27909020/the-design-and-transformation-of-biofundamentals-a-nonsurvey-introductory-evolutionary-and-molecular-biology-course
#16
Michael W Klymkowsky, Jeremy D Rentsch, Emina Begovic, Melanie M Cooper
Many introductory biology courses amount to superficial surveys of disconnected topics. Often, foundational observations and the concepts derived from them and students' ability to use these ideas appropriately are overlooked, leading to unrealistic expectations and unrecognized learning obstacles. The result can be a focus on memorization at the expense of the development of a meaningful framework within which to consider biological phenomena. About a decade ago, we began a reconsideration of what an introductory course should present to students and the skills they need to master...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27908846/the-effectiveness-of-web-based-asthma-self-management-system-my-asthma-portal-map-a-pilot-randomized-controlled-trial
#17
Sara Ahmed, Pierre Ernst, Susan J Bartlett, Marie-France Valois, Tasneem Zaihra, Guy Paré, Roland Grad, Owis Eilayyan, Robert Perreault, Robyn Tamblyn
BACKGROUND: Whether Web-based technologies can improve disease self-management is uncertain. My Asthma Portal (MAP) is a Web-based self-management support system that couples evidence-based behavioral change components (self-monitoring of symptoms, physical activity, and medication adherence) with real-time monitoring, feedback, and support from a nurse case manager. OBJECTIVE: The aim of this study was to compare the impact of access to a Web-based asthma self-management patient portal linked to a case-management system (MAP) over 6 months compared with usual care on asthma control and quality of life...
December 1, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27908844/quittr-the-design-of-a-video-game-to-support-smoking-cessation
#18
Ivan Bindoff, Kristy de Salas, Gregory Peterson, Tristan Ling, Ian Lewis, Lindsay Wells, Peter Gee, Stuart G Ferguson
BACKGROUND: Smoking is recognized as the largest, single, preventable cause of death and disease in the developed world. While the majority of smokers report wanting to quit, and many try each year, smokers find it difficult to maintain long-term abstinence. Behavioral support, such as education, advice, goal-setting, and encouragement, is known to be beneficial in improving the likelihood of succeeding in a quit attempt, but it remains difficult to effectively deliver this behavioral support and keep the patient engaged with the process for a sufficient duration...
December 1, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27908080/behavioral-manifestations-of-audiometrically-defined-slight-or-hidden-hearing-loss-revealed-by-measures-of-binaural-detection
#19
Leslie R Bernstein, Constantine Trahiotis
This study assessed whether audiometrically-defined "slight" or "hidden" hearing losses might be associated with degradations in binaural processing as measured in binaural detection experiments employing interaurally delayed signals and maskers. Thirty-one listeners participated, all having no greater than slight hearing losses (i.e., no thresholds greater than 25 dB HL). Across the 31 listeners and consistent with the findings of Bernstein and Trahiotis [(2015). J. Acoust. Soc. Am. 138, EL474-EL479] binaural detection thresholds at 500 Hz and 4 kHz increased with increasing magnitude of interaural delay, suggesting a loss of precision of coding with magnitude of interaural delay...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27908046/band-importance-functions-of-listeners-with-cochlear-implants-using-clinical-maps
#20
Adam K Bosen, Monita Chatterjee
Band importance functions estimate the relative contribution of individual acoustic frequency bands to speech intelligibility. Previous studies of band importance in listeners with cochlear implants have used experimental maps and direct stimulation. Here, band importance was estimated for clinical maps with acoustic stimulation. Listeners with cochlear implants had band importance functions that relied more heavily on lower frequencies and showed less cross-listener consistency than in listeners with normal hearing...
November 2016: Journal of the Acoustical Society of America
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