keyword
MENU ▼
Read by QxMD icon Read
search

metal toxicity

keyword
https://www.readbyqxmd.com/read/28343039/study-of-trace-metal-imbalances-in-the-blood-scalp-hair-and-nails-of-oral-cancer-patients-from-pakistan
#1
Muhammad Abdul Qayyum, Munir H Shah
Oral cancer is an important cause of cancer morbidity and mortality globally and exposure to trace metals alongside tobacco, alcohol and HPV are the important etiological factors in its development. Selected essential and toxic trace metals (Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn) were measured in the blood, scalp hair and nails of oral cancer patients and counterpart controls by atomic absorption spectrometry. Mean concentrations of Cd, Ni and Pb were found to be significantly higher (p<0.05) and those of Cu, Fe and Zn were considerably lower in the blood, scalp hair and nails of the patients than the controls...
March 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28342548/in-situ-reactive-zone-with-modified-mg-oh-2-for-remediation-of-heavy-metal-polluted-groundwater-immobilization-and-interaction-of-cr-iii-pb-ii-and-cd-ii
#2
Jun Dong, Bowen Li, Qiburi Bao
Mg(OH)2 dissolves slowly and can provide a long-term source of alkalinity, thus a promising alternative reagent for the in situ remediation of heavy metal polluted groundwater. However, the application of Mg(OH)2 on in situ reactive zone (IRZ) for heavy metal polluted groundwater has never been investigated. In this study, the behaviors of heavy metals in a Mg(OH)2 IRZ were monitored for 45d. The heavy metals show a sequential precipitation by modified Mg(OH)2 due to the difference of Ksp. Column tests were conducted to investigate the temporal and spatial distribution of heavy metals in Mg(OH)2 IRZ and evaluate the stabilization effect for multi-heavy metal polluted groundwater...
February 24, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28340464/a-review-on-various-electrochemical-techniques-for-heavy-metal-ions-detection-with-different-sensing-platforms
#3
REVIEW
BabanKumar Bansod, Tejinder Kumar, Ritula Thakur, Shakshi Rana, Inderbir Singh
Heavy metal ions are non-biodegradable and contaminate most of the natural resources occurring in the environment including water. Some of the heavy metals including Lead (Pb), Mercury (Hg), Arsenic (As), Chromium (Cr) and Cadmium (Cd) are considered to be highly toxic and hazardous to human health even at trace levels. This leads to the requirement of fast, accurate and reliable techniques for the detection of heavy metal ions. This review presents various electrochemical detection techniques for heavy metal ions those are user friendly, low cost, provides on-site and real time monitoring as compared to other spectroscopic and optical techniques...
March 18, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28340458/toxic-effects-of-environmental-pollutants-comparative-investigation-using-allium-cepa-l-and-lactuca-sativa-l
#4
Graciele Lurdes Silveira, Maria Gabriela Franco Lima, Gabriela Barreto Dos Reis, Marcel José Palmieri, Larissa Fonseca Andrade-Vieria
Studies that help understand the mechanisms of action of environmental pollutants are extremely important in environmental toxicology. In this context, assays using plants as models stand out for their simplicity and low performance cost. Among the plants used for this purpose, Allium cepa L. is the model most commonly applied for cytogenotoxic tests, while Lactuca sativa L., already widely used in phytotoxic investigations, has been gaining prominence in cytotoxic analyses. The present study aimed to compare the responses of A...
March 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28340400/pharmacoinformatics-exploration-of-polyphenol-oxidases-leading-to-novel-inhibitors-by-virtual-screening-and-molecular-dynamic-simulation-study
#5
Mubashir Hassan, Qamar Abbas, Zaman Ashraf, Ahmed A Moustafa, Sung-Yum Seo
Polyphenol oxidases (PPOs)/tyrosinases are metal-dependent enzymes and known as important targets for melanogenesis. Although considerable attempts have been conducted to control the melanin-associated diseases by using various inhibitors. However, the exploration of the best anti-melanin inhibitor without side effect still remains a challenge in drug discovery. In present study, protein structure prediction, ligand-based pharmacophore modeling, virtual screening, molecular docking and dynamic simulation study were used to screen the strong novel inhibitor to cure melanogenesis...
March 15, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28340386/constructed-ils-coated-porous-magnetic-nickel-cobaltate-hexagonal-nanoplates-sensing-materials-for-the-simultaneous-detection-of-cumulative-toxic-metals
#6
Yuanyuan Dong, Lei Zhang
The different morphologies of magnetic nickel cobaltate (NiCo2O4) electrocatalysts, consisting of nanoparticles (NiCo2O4-N), nanoplates (NiCo2O4-P) and microspheres (NiCo2O4-S) were fabricated. It was found that the electrocatalytic properties of the sensing materials were strongly dependent on morphology and specific surface area. The porous NiCo2O4 hexagonal nanoplates coupled with ILs as modified materials (ILs@NiCo2O4-P) for the simultaneous determination of thallium (Tl(+)), lead (Pb(2+)) and copper (Cu(2+)), exhibited high sensitivity, long-time stability and good repeatability...
March 18, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28340357/ruthenium-complexes-with-phenylterpyridine-derivatives-target-cell-membrane-and-trigger-death-receptors-mediated-apoptosis-in-cancer-cells
#7
Zhiqin Deng, Pan Gao, Lianling Yu, Bin Ma, Yuanyuan You, Leung Chan, Chaoming Mei, Tianfeng Chen
Elucidation of the communication between metal complexes and cell membrane may provide useful information for rational design of metal-based anticancer drugs. Herein we synthesized a novel class of ruthenium (Ru) complexes containing phtpy derivatives (phtpy = phenylterpyridine), analyzed their structure-activity relationship and revealed their action mechanisms. The result showed that, the increase in the planarity of hydrophobic Ru complexes significantly enhanced their lipophilicity and cellular uptake...
March 18, 2017: Biomaterials
https://www.readbyqxmd.com/read/28339194/a-systematic-evaluation-of-chronic-metal-mixture-toxicity-to-three-species-and-implications-for-risk-assessment
#8
Charlotte Nys, Liske Versieren, Katherine Cordery, Ronny Blust, Erik Smolders, Karel A C De Schamphelaere
Metal contamination generally occurs as mixtures. However, it is yet unresolved how to address metal mixtures in risk assessment. Therefore, using consistent methodologies, we have set up experiments to identify which mixture model applies best at low level effects, i.e. the independent action (IA) or concentration addition (CA) reference model. Toxicity of metal mixtures (Ni, Zn, Cu, Cd, and Pb) to Daphnia magna, Ceriodaphnia dubia, and Hordeum vulgare was investigated in different waters or soils, totaling 30 different experiments...
March 24, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28339049/kidney-and-heavy-metals-the-role-of-environmental-exposure-review
#9
Paolo Lentini, Luca Zanoli, Antonio Granata, Salvatore Santo Signorelli, Pietro Castellino, Roberto Dell'Aquila
Heavy metals are extensively used in agriculture and industrial applications such as production of pesticides, batteries, alloys, and textile dyes. Prolonged, intensive or excessive exposure can induce related systemic disorders. Kidney is a target organ in heavy metal toxicity for its capacity to filter, reabsorb and concentrate divalent ions. The extent and the expression of renal damage depends on the species of metals, the dose, and the time of exposure. Almost always acute kidney impairment differs from chronic renal failure in its mechanism and in the magnitude of the outcomes...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28339013/immunological-effects-of-occupational-exposure-to-lead-review
#10
Concettina Fenga, Silvia Gangemi, Valentina Di Salvatore, Luca Falzone, Massimo Libra
It is well-known that occupational and environmental exposure to several factors, including benzene, heavy metals, chemicals and mineral fibers, is associated with the risk of developing a great number of diseases. Numerous studies have been carried out in order to investigate the mechanisms of toxicity of these substances, with particular regard to the possible toxic effects on the immune system. However, little is known about the influence of heavy metals, such as lead, on the immune system in human populations...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28338629/study-of-the-accumulation-of-toxic-and-essential-ultra-trace-elements-in-fruits-of-sorbus-domestica-l
#11
Michaela Zeiner, Iva Juranović Cindrić, Boris Majić, Gerhard Stingeder
In the present work, the accumulation of selected toxic and essential ultra-trace elements in fruits of service tree (Sorbus domestica L.) were determined depending on harvest time. Samples were collected from the same sampling area in two different years and within one year in September and October (maturity state). Harvesting the fruits in the same area excludes the influence of metals taken up via roots, thus the impact of airborne contamination by heavy metal translocation can be studied. All samples were dried and digested using an acidic microwave assisted digestion system prior to quantification by inductively coupled plasma-sector field mass spectrometry (ICP-SFMS)...
March 24, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28337621/metal-contaminated-potato-crops-and-potential-human-health-risk-in-bolivian-mining-highlands
#12
Alan E Garrido, William H J Strosnider, Robin Taylor Wilson, Janette Condori, Robert W Nairn
This study assessed metals in irrigation water, soil and potato crops impacted by mining discharges, as well as potential human health risk in the high desert near the historic mining center of Potosí, Bolivia. Metal concentrations were compared with international concentration limit guidelines. In addition, an ingested average daily dose and minimum risk level were used to determine the hazard quotient from potato consumption for adults and children. Irrigation water maximum concentrations of Cd, Pb and Zn in mining-impacted sites were elevated 20- to 1100-fold above international concentration limit guidelines...
March 23, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28337565/blood-trace-metals-in-a-sporadic-amyotrophic-lateral-sclerosis-geographical-cluster
#13
Stefano De Benedetti, Giorgio Lucchini, Cristian Del Bò, Valeria Deon, Alessandro Marocchi, Silvana Penco, Christian Lunetta, Elisabetta Gianazza, Francesco Bonomi, Stefania Iametti
Amyotrophic lateral sclerosis (ALS) is a fatal disorder with unknown etiology, in which genetic and environmental factors interplay to determine the onset and the course of the disease. Exposure to toxic metals has been proposed to be involved in the etiology of the disease either through a direct damage or by promoting oxidative stress. In this study we evaluated the concentration of a panel of metals in serum and whole blood of a small group of sporadic patients, all living in a defined geographical area, for which acid mine drainage has been reported...
March 23, 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/28337404/revising-reach-guidance-on-information-requirements-and-chemical-safety-assessment-for-engineered-nanomaterials-for-aquatic-ecotoxicity-endpoints-recommendations-from-the-envnano-project
#14
Steffen Foss Hansen, Sara Nørgaard Sørensen, Lars Michael Skjolding, Nanna B Hartmann, Anders Baun
The European Chemical Agency (ECHA) is in the process of revising its guidance documents on how to address the challenges of ecotoxicological testing of nanomaterials. In these revisions, outset is taken in the hypothesis that ecotoxicological test methods, developed for soluble chemicals, can be made applicable to nanomaterials. European Research Council project EnvNano-Environmental Effects and Risk Evaluation of Engineered, which ran from 2011 to 2016, took another outset by assuming that: "The behaviour of nanoparticles in suspension is fundamentally different from that of chemicals in solution"...
2017: Environmental Sciences Europe
https://www.readbyqxmd.com/read/28336926/alleviation-of-mercury-toxicity-to-a-marine-copepod-under-multigenerational-exposure-by-ocean-acidification
#15
Yan Li, Wen-Xiong Wang, Minghua Wang
Ocean acidification (OA) may potentially modify the responses of aquatic organisms to other environmental stressors including metals. In this study, we investigated the effects of near-future OA (pCO2 1000 μatm) and mercury (Hg) on the development and reproduction of marine copepod Tigriopus japonicus under multigenerational life-cycle exposure. Metal accumulation as well as seven life history traits (survival rate, sex ratio, developmental time from nauplius to copepodite, developmental time from nauplius to adult, number of clutches, number of nauplii/clutch and fecundity) was quantified for each generation...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28336855/behavior-and-potential-impacts-of-metal-based-engineered-nanoparticles-in-aquatic-environments
#16
REVIEW
Cheng Peng, Wen Zhang, Haiping Gao, Yang Li, Xin Tong, Kungang Li, Xiaoshan Zhu, Yixiang Wang, Yongsheng Chen
The specific properties of metal-based nanoparticles (NPs) have not only led to rapidly increasing applications in various industrial and commercial products, but also caused environmental concerns due to the inevitable release of NPs and their unpredictable biological/ecological impacts. This review discusses the environmental behavior of metal-based NPs with an in-depth analysis of the mechanisms and kinetics. The focus is on knowledge gaps in the interaction of NPs with aquatic organisms, which can influence the fate, transport and toxicity of NPs in the aquatic environment...
January 22, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28336439/reproductive-toxicity-provoked-by-titanium-dioxide-nanoparticles-and-the-ameliorative-role-of-tiron-in-adult-male-rats
#17
Ashraf M Morgan, Marwa A Ibrahim, Peter A Noshy
Titanium dioxide nanoparticles (TDN) are widely used in paints, plastics, ceramics, cosmetics, printing ink, rubber and paper. Tiron is a water soluble metal chelator and antioxidant. This study was designed to investigate the reproductive toxicity of TDN in male albino rats and the ameliorative role of Tiron to minimize such toxic effects. Eighty adult male albino rats were assigned into 4 equal groups, group 1: control; group 2: received TDN at 100 mg/kg/day orally for 8 weeks; group 3: received Tiron at 470 mg/kg/day intraperitoneally for 2 weeks (the last 2 weeks of the experimental period); group 4: received both TDN and Tiron by the same previously mentioned dose, route and duration...
March 20, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28336334/agricultural-utilization-of-biosolids-a-review-on-potential-effects-on-soil-and-plant-grown
#18
REVIEW
Bhavisha Sharma, Abhijit Sarkar, Pooja Singh, Rajeev Pratap Singh
Environmental and economic implications linked with the proper ecofriendly disposal of modern day wastes, has made it essential to come up with alternative waste management practices that reduce the environmental pressures resulting from unwise disposal of such wastes. Urban wastes like biosolids are loaded with essential plant nutrients. In this view, agricultural use of biosolids would enable recycling of these nutrients and could be a sustainable approach towards management of this hugely generated waste...
March 20, 2017: Waste Management
https://www.readbyqxmd.com/read/28336207/heavy-metal-concentrations-in-some-gastropods-and-bivalves-collected-from-the-fishing-zone-of-south-india
#19
A S Ragi, P P Leena, Eldhose Cheriyan, S M Nair
The present study investigates heavy metal concentrations in gastropods and bivalves collected from major fishing centers in South India. Three gastropods, Bursa spinosa, Tibia curta, and Murex trapa, and two bivalves, Perna viridis and Villoritta cyprinoids, were collected for the analysis of heavy metals. The metals in the present study followed the order Mg>Ca>Zn>Fe>Cu>Mn>Cr>Pb>Ni>Co>Cd. Trace metal concentrations in the soft tissue of the molluscs varied as follows: for Cd: 0...
March 20, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28336206/toxic-metal-pollution-in-the-yellow-sea-and-bohai-sea-china-distribution-controlling-factors-and-potential-risk
#20
Cailing Xiao, Huimin Jian, Lufeng Chen, Chang Liu, Huayang Gao, Chuansong Zhang, Shengkang Liang, Yanbin Li
The Bohai Sea (BS) and Yellow Sea (YS), which are adjacent to the most urbanized and industrialized areas in China, are facing a variety of environmental problems. Two cruises were conducted to investigate the pollution status of toxic metals in BS and YS sediments. They generally presented a decreasing trend from near shore to offshore. In addition, two high concentration areas were observed in the central south YS and north of the Shandong Peninsula. The results of multiple regression analyses suggest that Hg is mainly controlled by anthropogenic loading, whereas for Cr, Cu, Ni, Pb and Zn, sediment properties, especially the Fe oxides content, play a more important role...
March 20, 2017: Marine Pollution Bulletin
keyword
keyword
97489
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"