keyword
https://read.qxmd.com/read/38479620/undescribed-2-7-neolignans-and-polyoxygenated-cyclohexene-glycosides-from-the-aerial-parts-of-piper-mutabile-c-dc-and-their-inhibitory-effects-on-nitric-oxide-production
#21
JOURNAL ARTICLE
Phan Van Kiem, Nguyen Xuan Nhiem, Nguyen Huy Hoang, Ngo Anh Bang, Pham Hai Yen, Do Thi Trang, Duong Thi Dung, Nguyen Thi Cuc, Phan Thi Thanh Huong, Bui Huu Tai
A phytochemical study of the aerial parts of Piper mutabile C. DC. revealed seven undescribed compounds [two (2-7')-neolignans and five polyoxygenated cyclohexene glycosides] and six known propenylcatechol derivatives. The chemical structures of the isolated compounds were elucidated by extensive HR-ESI-MS and NMR analyses, as well as comparison with the literature. The absolute configurations of the (2-7')-neolignans were confirmed by GIAO 13 C NMR calculations with a sorted training set strategy and TD-DFT calculation ECD spectra...
March 11, 2024: Fitoterapia
https://read.qxmd.com/read/38476944/the-archaeome-in-metaorganism-research-with-a-focus-on-marine-models-and-their-bacteria-archaea-interactions
#22
JOURNAL ARTICLE
Avril J E von Hoyningen-Huene, Corinna Bang, Philipp Rausch, Malte Rühlemann, Hanna Fokt, Jinru He, Nadin Jensen, Mirjam Knop, Carola Petersen, Lara Schmittmann, Thorsten Zimmer, John F Baines, Thomas C G Bosch, Ute Hentschel, Thorsten B H Reusch, Thomas Roeder, Andre Franke, Hinrich Schulenburg, Eva Stukenbrock, Ruth A Schmitz
Metaorganism research contributes substantially to our understanding of the interaction between microbes and their hosts, as well as their co-evolution. Most research is currently focused on the bacterial community, while archaea often remain at the sidelines of metaorganism-related research. Here, we describe the archaeome of a total of eleven classical and emerging multicellular model organisms across the phylogenetic tree of life. To determine the microbial community composition of each host, we utilized a combination of archaea and bacteria-specific 16S rRNA gene amplicons...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38476641/the-role-of-ki-67-in-hr-her2-breast-cancer-a-real-world-study-of-956-patients
#23
JOURNAL ARTICLE
Qin Ma, Yao-Bang Liu, Tong She, Xin-Lan Liu
OBJECTIVE: This study determined the cut-off value of Ki-67 expression and discussed the interaction between Ki-67 and histological grade, further explored the prognostic role of Ki-67 in hormone receptor-positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer;. MATERIALS AND METHODS: We assessed the Ki-67 expression of 956 patients with HR+/HER2 breast cancer diagnosed in the General Hospital of Ningxia Medical University from 2015 to 2019 by immunohistochemistry (IHC), The disease-free survival (DFS) was defined as the time from postoperative to the first local recurrence, distant metastasis or death of the disease...
2024: Breast Cancer: Targets and Therapy
https://read.qxmd.com/read/38476500/association-between-risk-of-obstructive-sleep-apnea-severity-and-risk-of-severe-covid-19-symptoms-insights-from-salivary-and-serum-cytokines
#24
JOURNAL ARTICLE
Yen Dinh, Abdullah Alawady, Hesham Alhazmi, Khaled Altabtbaei, Marcelo Freire, Mohammad Alghounaim, Sriraman Devarajan, Fahd Al Mulla, Saadoun Bin-Hassan, Hend Alqaderi
OBJECTIVES: Obstructive sleep apnea (OSA) can adversely affect the immune response through clinical factors such as hypoxia, inflammation, and sleep disturbance. Since SARS-CoV-2 heavily relies on local and systemic host immune responses, this study aims to examine the links between the severity of OSA risk, cytokine levels, and the severity of symptoms associated with SARS-CoV-2 infection. METHODS: Saliva and blood samples from 50 COVID-19 patients and 30 non-infected hospital staff members were collected...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38474982/entropy-sharing-in-ransomware-bypassing-entropy-based-detection-of-cryptographic-operations
#25
JOURNAL ARTICLE
Jiseok Bang, Jeong Nyeo Kim, Seungkwang Lee
This study presents a groundbreaking approach to the ever-evolving challenge of ransomware detection. A lot of detection methods predominantly rely on pinpointing high-entropy blocks, which is a hallmark of the encryption techniques commonly employed in ransomware. These blocks, typically difficult to recover, serve as key indicators of malicious activity. So far, many neutralization techniques have been introduced so that ransomware utilizing standard encryption can effectively bypass these entropy-based detection systems...
February 23, 2024: Sensors
https://read.qxmd.com/read/38474636/aptamer-technologies-in-neuroscience-neuro-diagnostics-and-neuro-medicine-development
#26
REVIEW
Bang Wang, Firas Kobeissy, Mojtaba Golpich, Guangzheng Cai, Xiaowei Li, Reem Abedi, William Haskins, Weihong Tan, Steven A Benner, Kevin K W Wang
Aptamers developed using in vitro Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technology are single-stranded nucleic acids 10-100 nucleotides in length. Their targets, often with specificity and high affinity, range from ions and small molecules to proteins and other biological molecules as well as larger systems, including cells, tissues, and animals. Aptamers often rival conventional antibodies with improved performance, due to aptamers' unique biophysical and biochemical properties, including small size, synthetic accessibility, facile modification, low production cost, and low immunogenicity...
March 2, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38474190/roles-of-cgede1-and-cgmca-in-development-and-virulence-of-colletotrichum-gloeosporioides
#27
JOURNAL ARTICLE
Dan Wang, Bang An, Hongli Luo, Chaozu He, Qiannan Wang
Anthracnose, induced by Colletotrichum gloeosporioides , poses a substantial economic threat to rubber tree yields and various other tropical crops. Ede1, an endocytic scaffolding protein, plays a crucial role in endocytic site initiation and maturation in yeast. Metacaspases, sharing structural similarities with caspase family proteases, are essential for maintaining cell fitness. To enhance our understanding of the growth and virulence of C. gloeosporioides , we identified a homologue of Ede1 (CgEde1) in C...
March 3, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38474183/cgcfem1-is-required-for-the-full-virulence-of-colletotrichum-gloeosporioides
#28
JOURNAL ARTICLE
Liping Feng, Meixia Dong, Zhirui Huang, Qian Wang, Bang An, Chaozu He, Qiannan Wang, Hongli Luo
Colletotrichum gloeosporioides is widely distributed and causes anthracnose on many crops, resulting in serious economic losses. Common fungal extracellular membrane (CFEM) domain proteins have been implicated in virulence and their interaction with the host plant, but their roles in C. gloeosporioides are still unknown. In this study, a CFEM-containing protein of C. gloeosporioides was identified and named as CgCFEM1. The expression levels of CgCFEM1 were found to be markedly higher in appressoria, and this elevated expression was particularly pronounced during the initial stages of infection in the rubber tree...
March 2, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38472700/pulmonary-hypertension-in-newly-diagnosed-obstructive-sleep-apnea-chronic-obstructive-pulmonary-disease-overlap-syndrome-patients-attending-a-tertiary-care-centre-a-cross-sectional-analysis
#29
JOURNAL ARTICLE
Jyothi Reshma S, Sunny George, Santhosh Kumar P
INTRODUCTION: Overlap syndrome is the association of obstructive sleep apnea (OSA) with chronic obstructive pulmonary disorder and with other chronic respiratory diseases. Patients with overlap syndrome have a worse prognosis compared with chronic obstructive pulmonary disorder or OSA alone. Additionally, patients with combined chronic obstructive pulmonary disorder and OSA are more likely to develop pulmonary hypertension and right heart failure much earlier than those without overlap...
March 12, 2024: Irish Journal of Medical Science
https://read.qxmd.com/read/38471349/vietnamese-consumer-s-perspective-on-green-beauty-care-products-exploring-the-impact-of-animal-welfare-concerns-and-skepticism-toward-green-advertising
#30
JOURNAL ARTICLE
Bang Nguyen-Viet, Anh Thi Lan Nguyen
Green consumers increasingly consider animal welfare (AW) in their decision-making, demonstrating a growing awareness of ethical considerations beyond conventional environmental concerns. However, with an increase in greenwashing, skepticism has grown among consumers. Regardless of manufacturers' efforts to enhance consumer awareness via green advertising, consumer skepticism toward these advertisements creates doubt and consequently reduces positive attitudes and intentions to buy green products. This study investigated the variables that impact Vietnamese consumers' decision-making processes toward green beauty care products...
March 11, 2024: Acta Psychologica
https://read.qxmd.com/read/38469999/pharmacokinetic-and-safety-comparison-of-fixed-dose-combination-of-cilostazol-rosuvastatin-200-20-mg-versus-concurrent-administration-of-the-separate-components-in-healthy-adults
#31
JOURNAL ARTICLE
Jae Hoon Kim, Jang Hee Hong, Jin-Gyu Jung, Won Tae Jung, Kyu-Yeol Nam, Jae Seok Roh, Youn Woong Choi, Junbae Bang, Hyunwook Huh, Hye J Lee, JungHa Moon, Jaehee Kim, Jung Sunwoo
The combined cilostazol and rosuvastatin therapy is frequently used for coronary artery disease treatment. This open-label, 3 × 3 crossover clinical trial evaluated the pharmacokinetics and safety of a fixed-dose combination (FDC) of cilostazol/rosuvastatin (200 + 20 mg) versus a concurrent administration of the separate components (SCs) under both fasted and fed conditions. Among 48 enrolled healthy adults, 38 completed the study. Participants were administered a single oral dose of cilostazol/rosuvastatin (200 + 20 mg), either as an FDC or SCs in a fasted state, or FDC in a fed state, in each period of the trial...
March 12, 2024: Clinical Pharmacology in Drug Development
https://read.qxmd.com/read/38468729/the-influences-of-the-covid-19-pandemic-on-klebsiella-pneumoniae-infection-in-children-henan-china-2018-2022
#32
JOURNAL ARTICLE
Bang Du, Meng Sun, Xueyi Qin, Huanmin Wang, Jushan Sun, Jieming Li, Xianwei Zhang, Wancun Zhang
No abstract text is available yet for this article.
March 2024: Indian Journal of Microbiology
https://read.qxmd.com/read/38468077/comparison-of-tracheal-versus-esophageal-temperatures-during-laparoscopic-surgery
#33
JOURNAL ARTICLE
Eun Kyung Lee, Yu Jeong Bang, Jeayoun Kim, Hyun Joo Ahn
PURPOSE: Recently, endotracheal tubes with an embedded temperature sensor in the inner surface of the tube cuff (temperature tracheal tubes) have been developed. We sought to assess whether temperature tracheal tubes show a good agreement with esophageal temperature probes during surgery. METHODS: We enrolled 40 patients who underwent laparoscopic surgery in an observational study. The tracheas of all patients were intubated with a temperature tracheal tube, and an esophageal temperature probe was inserted into the esophagus...
March 11, 2024: Canadian Journal of Anaesthesia
https://read.qxmd.com/read/38467827/rna-expression-of-6-genes-from-metastatic-mucosal-gastric-cancer-serves-as-the-global-prognostic-marker-for-gastric-cancer-with-functional-validation
#34
JOURNAL ARTICLE
Yun-Suhk Suh, Jieun Lee, Joshy George, Donghyeok Seol, Kyoungyun Jeong, Seung-Young Oh, Chanmi Bang, Yukyung Jun, Seong-Ho Kong, Hyuk-Joon Lee, Jong-Il Kim, Woo Ho Kim, Han-Kwang Yang, Charles Lee
BACKGROUND: Molecular analysis of advanced tumors can increase tumor heterogeneity and selection bias. We developed a robust prognostic signature for gastric cancer by comparing RNA expression between very rare early gastric cancers invading only mucosal layer (mEGCs) with lymph node metastasis (Npos) and those without metastasis (Nneg). METHODS: Out of 1003 mEGCs, all Npos were matched to Nneg using propensity scores. Machine learning approach comparing Npos and Nneg was used to develop prognostic signature...
March 11, 2024: British Journal of Cancer
https://read.qxmd.com/read/38467670/point-of-care-lung-ultrasound-predicts-hyperferritinemia-and-hospitalization-but-not-elevated-troponin-in-sars-cov-2-viral-pneumonitis-in-children
#35
JOURNAL ARTICLE
Paul Walsh, Andrea Hankins, Heejung Bang
SARS-CoV-2 often causes viral pneumonitis, hyperferritinemia, elevations in D-dimer, lactate dehydrogenase (LDH), transaminases, troponin, CRP, and other inflammatory markers. Lung ultrasound is increasingly used to diagnose and stratify viral pneumonitis severity. We retrospectively reviewed 427 visits in patients aged 14 days to 21 years who had had a point-of-care lung ultrasound in our pediatric emergency department from 30/November/2019 to 14/August/2021. Lung ultrasounds were categorized using a 6-point ordinal scale...
March 11, 2024: Scientific Reports
https://read.qxmd.com/read/38467125/glaucoma-challenges-and-opportunities
#36
EDITORIAL
Michael Kalloniatis, Bang B Bui, Jack Phu
No abstract text is available yet for this article.
March 2024: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://read.qxmd.com/read/38466092/targeted-sequencing-from-cerebrospinal-fluid-for-rapid-identification-of-drug-resistant-tuberculous-meningitis
#37
JOURNAL ARTICLE
Trinh Thi Bich Tram, Le Pham Tien Trieu, Le Thanh Hoang Nhat, Do Dang Anh Thu, Nguyen Le Quang, Nguyen Duc Bang, Tran Thi Hong Chau, Guy E Thwaites, Timothy M Walker, Vu Thi Ngoc Ha, Nguyen Thuy Thuong Thuong
Mortality from tuberculous meningitis (TBM) remains around 30%, with most deaths occurring within 2 months of starting treatment. Mortality from drug-resistant strains is higher still, making early detection of drug resistance (DR) essential. Targeted next-generation sequencing (tNGS) produces high read depths, allowing the detection of DR-associated alleles with low frequencies. We applied Deeplex Myc-TB-a tNGS assay-to cerebrospinal fluid (CSF) samples from 72 adults with microbiologically confirmed TBM and compared its genomic drug susceptibility predictions to a composite reference standard of phenotypic susceptibility testing (pDST) and whole genome sequencing, as well as to clinical outcomes...
March 11, 2024: Journal of Clinical Microbiology
https://read.qxmd.com/read/38464103/the-bmal1-hif2a-heterodimer-modulates-circadian-variations-of-myocardial-injury
#38
Holger Eltzschig, Wei Ruan, Tao Li, Jaewoong Lee, In Hyuk Bang, Wankun Deng, Xinxin Ma, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Yu An, Yin-Ying Wang, Yafen Liang, Matthew Deberge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua Gorham, Jonathan Seidman, Christine Seidman, Sary Aranki, Ragini Nair, Lei Li, Jagat Narula, Zhongming Zhao, Alemayehu Gorfe, Jochen Muehlschlegel, Kuang-Lei Tsai
Acute myocardial infarction stands as a prominent cause of morbidity and mortality worldwide 1-6 . Clinical studies have demonstrated that the severity of cardiac injury following myocardial infarction exhibits a circadian pattern, with larger infarct sizes and poorer outcomes in patients experiencing morning onset myocardial infarctions 7-14 . However, the molecular mechanisms that govern circadian variations of myocardial injury remain unclear. Here, we show that BMAL1 14-20 , a core circadian transcription factor, orchestrates diurnal variability in myocardial injury...
February 28, 2024: Research Square
https://read.qxmd.com/read/38461741/optimal-blood-pressure-for-stroke-prevention-in-healthy-adults-below-65-years-a-nationwide-10-year-observational-study
#39
JOURNAL ARTICLE
So Im Ryu, Sang Hyo Lee, Hyoung Soo Byoun, Young-Deok Kim, Seung Pil Ban, Jae Seung Bang, O-Ki Kwon, Chang Wan Oh, Si Un Lee
BACKGROUND: There have been few reports on the preventative value of intensive blood pressure (BP) management for stroke since the American College of Cardiology/American Heart Association (ACC/AHA) announced the new criteria for hypertension (HTN) in 2017. This study aimed to identify optimal BP for prevention of stroke in healthy adults under 65 years. METHODS: We conducted a 10-year observational study on the risk of stroke, subclassified as hemorrhagic stroke (HS) or ischemic stroke (IS), according to BP categories (low-normal BP, high-normal BP, elevated BP, stage 1 HTN, and stage 2 HTN) using the National Health Insurance Service Database...
March 9, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/38460843/using-cumgfe-layered-double-oxide-to-replace-laccase-as-a-catalyst-for-abiotic-humification
#40
JOURNAL ARTICLE
Vu Khac Hoang Bui, Xuan Cuong Nguyen, Hai Bang Truong, Jin Hur
Humification offers a promising avenue for sequestering dissolved organic carbon while facilitating environmental cleanup. In this study, CuMgFe layered double oxides (LDO) were applied as a catalyst to replace conventional enzymes, such as laccase, thereby enhancing the in vitro polyphenol-Maillard humification reaction. CuMgFe LDO was synthesized through calcination of CuMgFe layered double hydroxides (LDH) at 500 °C for 5 h. A suite of characterization methods confirmed the successful formation into mixed oxides (Cu2 O, CuO, MgO, FeO, and Fe2 O3 ) after thermal treatment...
March 7, 2024: Chemosphere
keyword
keyword
97485
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.