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https://www.readbyqxmd.com/read/28445206/independent-effects-of-blood-pressure-and-parathyroid-hormone-on-aortic-pulse-wave-velocity-in-untreated-chinese-patients
#1
Yi-Bang Cheng, Li-Hua Li, Qian-Hui Guo, Fei-Ka Li, Qi-Fang Huang, Chang-Sheng Sheng, Ji-Guang Wang, Jan A Staessen, Yan Li
OBJECTIVE: Whether or not calcium-regulating hormones stiffen arteries independent of blood pressure (BP) is uncertain. We investigated the independent associations of carotid-femoral pulse wave velocity (PWV) with 25-hydroxy-vitamin D [25(OH)D], parathyroid hormone (PTH) and 24-h ambulatory BP in untreated Chinese patients. METHODS: Consecutive untreated patients referred for ambulatory BP monitoring were recruited. PWV was measured with a high-fidelity micromanometer and the SphygmoCor software (AtCor Medical, West Ryde, New South Wales, Australia)...
April 25, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28443181/development-of-a-test-method-for-the-evaluation-of-dna-damage-in-mouse-spermatogonial-stem-cells
#2
Hye Lyun Jeon, Jung-Sun Yi, Tae Sung Kim, Youkyung Oh, Hye Jeong Lee, Minseong Lee, Jin Seok Bang, Kinarm Ko, Il Young Ahn, Kyungyuk Ko, Joohwan Kim, Hye-Kyung Park, Jong Kwon Lee, Soo Jung Sohn
Although alternative test methods based on the 3Rs (Replacement, Reduction, Refinement) are being developed to replace animal testing in reproductive and developmental toxicology, they are still in an early stage. Consequently, we aimed to develop alternative test methods in male animals using mouse spermatogonial stem cells (mSSCs). Here, we modified the OECD TG 489 and optimized the in vitro comet assay in our previous study. This study aimed to verify the validity of in vitro tests involving mSSCs by comparing their results with those of in vivo tests using C57BL/6 mice by gavage...
April 2017: Toxicological Research
https://www.readbyqxmd.com/read/28441743/smartphone-location-independent-physical-activity-recognition-based-on-transportation-natural-vibration-analysis
#3
Taeho Hur, Jaehun Bang, Dohyeong Kim, Oresti Banos, Sungyoung Lee
Activity recognition through smartphones has been proposed for a variety of applications. The orientation of the smartphone has a significant effect on the recognition accuracy; thus, researchers generally propose using features invariant to orientation or displacement to achieve this goal. However, those features reduce the capability of the recognition system to differentiate among some specific commuting activities (e.g., bus and subway) that normally involve similar postures. In this work, we recognize those activities by analyzing the vibrations of the vehicle in which the user is traveling...
April 23, 2017: Sensors
https://www.readbyqxmd.com/read/28437977/polymer-optical-fiber-bragg-grating-inscription-with-a-single-uv-laser-pulse
#4
A Pospori, C A F Marques, O Bang, D J Webb, P André
We experimentally demonstrate the first polymer optical fiber Bragg grating inscribed with only one krypton fluoride laser pulse. The device has been recorded in a single-mode poly(methyl methacrylate) optical fiber, with a core doped with benzyl dimethyl ketal for photosensitivity enhancement. One laser pulse with a duration of 15 ns, which provide energy density of 974 mJ/cm<sup>2</sup>, is adequate to introduce a refractive index change of 0.74×10<sup>-4</sup> in the fiber core. After the exposure, the reflectivity of the grating increases for a few minutes following a second order exponential saturation...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28436494/platinum-nickel-alloy-excavated-nano-multipods-with-hexagonal-close-packed-structure-and-superior-activity-towards-hydrogen-evolution-reaction
#5
Zhenming Cao, Qiaoli Chen, Jiawei Zhang, Huiqi Li, Yaqi Jiang, Shouyu Shen, Gang Fu, Bang-An Lu, Zhaoxiong Xie, Lansun Zheng
Crystal phase regulations may endow materials with enhanced or new functionalities. However, syntheses of noble metal-based allomorphic nanomaterials are extremely difficult, and only a few successful examples have been found. Herein, we report the discovery of hexagonal close-packed Pt-Ni alloy, despite the fact that Pt-Ni alloys are typically crystallized in face-centred cubic structures. The hexagonal close-packed Pt-Ni alloy nano-multipods are synthesized via a facile one-pot solvothermal route, where the branches of nano-multipods take the shape of excavated hexagonal prisms assembled by six nanosheets of 2...
April 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28435520/genetically-transforming-human-osteoblasts-to-sarcoma-development-of-an-osteosarcoma-model
#6
Yi Yang, Rui Yang, Michael Roth, Sajida Piperdi, Wendong Zhang, Howard Dorfman, Pulivarthi Rao, Amy Park, Sandeep Tripathi, Carrie Freeman, Yunjia Zhang, Rebecca Sowers, Jeremy Rosenblum, David Geller, Bang Hoang, Jonathan Gill, Richard Gorlick
Osteosarcoma is the most common primary malignant bone tumor in children and young adults. Although histologically defined by the presence of malignant osteoid, the tumor possesses lineage multipotency suggesting it could be derived from a cell anywhere on the differentiation pathway between a mesenchymal stem cell (MSC) and a mature osteoblast. To determine if preosteoblasts (pOB) could be the cell of origin differentiated MSCs were transformed with defined genetic elements. MSCs and pOB differentiated from the same MSCs were serially transformed with the oncogenes hTERT, SV40 large T antigen and H-Ras...
January 2017: Genes & Cancer
https://www.readbyqxmd.com/read/28434669/diurnal-variation-of-co2-ch4-and-n2o-emission-fluxes-continuously-monitored-in-situ-in-three-environmental-habitats-in-a-subtropical-estuarine-wetland
#7
Wen-Bin Yang, Chung-Shin Yuan, Chuan Tong, Pin Yang, Lei Yang, Bang-Qin Huang
Wetlands play a crucial role in modulating atmospheric concentrations of greenhouse gases (GHGs) such as carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O). The key factors controlling GHG emission from subtropical estuarine wetlands were investigated in this study, which continuously monitored the uptake/emission of GHGs (CO2, CH4, and N2O) by/from a subtropical estuarine wetland located in the Minjiang estuary in the coastal region of southeastern China. A self-designed floating chamber was used to collect air samples on-site at three environmental habitats (Phragmites australis marsh, mudflats, and river water)...
April 20, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28434167/analysis-of-s1p-receptor-expression-by-uterine-immune-cells-using-standardized-multi-parametric-flow-cytometry
#8
Jianhong Zhang, Annie Bang, Stephen J Lye
Flow cytometry is a powerful tool for phenotypic and functional analyses of single immune cells. The increasing capability of flow cytometry technology has driven a more detailed understanding of immune cell subsets and functions in complex cellular systems such as the developing human decidua/placenta. We propose a standardized procedure for the isolation and analysis of human decidual natural killer (dNK) cells and this method can be extended to investigation of other uterine lymphocytes. Here this platform is used to examine the expression of sphingosine-1-phosphate (S1P) receptor and functional growth factors by dNK cells...
April 23, 2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28430947/electrocardiographic-left-ventricular-hypertrophy-predicts-cardiovascular-morbidity-and-mortality-in-hypertensive-patients-the-allhat-study
#9
Casper N Bang, Elsayed Z Soliman, Lara M Simpson, Barry R Davis, Richard B Devereux, Peter M Okin
BACKGROUND: Electrocardiographic (ECG) left ventricular hypertrophy (LVH) is a strong predictor of cardiovascular (CV) morbidity and mortality. However, the predictive value of ECG LVH in treated hypertensive patients remains unclear. METHODS: A total of 33,357 patients (aged ≥ 55 years) with hypertension and at least 1 other coronary heart disease (CHD) risk factor were randomized to chlorthalidone, amlodipine, or lisinopril. The outcome of the present study was all-cause mortality; and secondary endpoints were CHD, nonfatal myocardial infarction (MI), stroke, angina, heart failure (HF), and peripheral arterial disease...
April 19, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28430740/low-dose-computed-tomography-scans-with-automatic-exposure-control-for-patients-of-different-ages-undergoing-cardiac-pet-ct-and-spect-ct
#10
Ching-Ching Yang, Bang-Hung Yang, Chun-Yuan Tu, Tung-Hsin Wu, Shu-Hsin Liu
PURPOSE: This study aimed to evaluate the efficacy of automatic exposure control (AEC) in order to optimize low-dose computed tomography (CT) protocols for patients of different ages undergoing cardiac PET/CT and single-photon emission computed tomography/computed tomography (SPECT/CT). METHODS: One PET/CT and one SPECT/CT were used to acquire CT images for four anthropomorphic phantoms representative of 1-year-old, 5-year-old and 10-year-old children and an adult...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28430230/compact-multichannel-high-resolution-micro-electro-mechanical-systems-based-interrogator-for-fiber-bragg-grating-sensing
#11
D Ganziy, B Rose, O Bang
We propose a novel type of compact high-resolution multichannel micro-electro-mechanical systems (MEMS)-based interrogator, where we replace the linear detector with a digital micromirror device (DMD). The DMD is typically cheaper and has better pixel sampling than an InGaAs detector used in the 1550 nm range, which leads to cost reduction and better performance. Moreover, the DMD is a 2D array, which means that multichannel systems can be implemented without any additional optical components in the interrogator...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430127/image-guided-laparoscopic-surgical-tool-iglast-based-on-the-optical-frequency-domain-imaging-ofdi-to-prevent-bleeding
#12
Byung Jun Park, Seung Rag Lee, Hyun Jin Bang, Byung Yeon Kim, Jeong Hun Park, Dong Guk Kim, Sung Soo Park, Young Jae Won
We present an image-guided laparoscopic surgical tool (IGLaST) to prevent bleeding. By applying optical frequency domain imaging (OFDI) to a specially designed laparoscopic surgical tool, the inside of fatty tissue can be observed before a resection, and the presence and size of blood vessels can be recognized. The optical sensing module on the IGLaST head has a diameter of less than 390 µm and is moved back and forth by a linear servo actuator in the IGLaST body. We proved the feasibility of IGLaST by in vivo imaging inside the fatty tissue of a porcine model...
April 21, 2017: Sensors
https://www.readbyqxmd.com/read/28429508/immunophenotyping-and-activation-status-of-maternal-peripheral-blood-leukocytes-during-pregnancy-and-labour-both-term-and-preterm
#13
Jianhong Zhang, Oksana Shynlova, Sally Sabra, Annie Bang, Laurent Briollais, Stephen J Lye
The onset of labour in rodents and in humans is associated with physiological inflammation which is manifested by infiltration of activated maternal peripheral leukocytes (mPLs) into uterine tissues. Here, we used flow cytometry to immunophenotype mPLs throughout gestation and labour, both term and preterm. Peripheral blood was collected from non-pregnant women and pregnant women in the 1st, 2nd and 3rd trimesters. Samples were also collected from women in active labour at term (TL) or preterm (PTL) and compared with women term not-in-labour (TNIL) and preterm not-in-labour (PTNIL)...
April 21, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28428774/biochar-addition-increases-the-rates-of-dissimilatory-iron-reduction-and-methanogenesis-in-ferrihydrite-enrichments
#14
Guo-Wei Zhou, Xiao-Ru Yang, Christopher W Marshall, Hu Li, Bang-Xiao Zheng, Yu Yan, Jian-Qiang Su, Yong-Guan Zhu
Biochar contains quinones and aromatic structures that facilitate extracellular electron transfer between microbial cells and insoluble minerals. In this study, granulated biochar (1.2-2 mm) and powdered biochar (<0.15 mm) were amended to two ferrihydrite (in situ ferrihydrite and ex situ ferrihydrite) enrichments to investigate the effect of biochar with different particle sizes on dissimilatory iron(III)-reducing bacteria (DIRB) and methanogens. Biochar addition significantly stimulated the reduction of both in situ ferrihydrite and ex situ ferrihydrite and the production of methane...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28427738/assessment-of-a-combined-dry-anaerobic-digestion-and-post-composting-treatment-facility-for-source-separated-organic-household-waste-using-material-and-substance-flow-analysis-and-life-cycle-inventory
#15
Morten Bang Jensen, Jacob Møller, Charlotte Scheutz
The fate of total solids, volatile solids, total organic carbon, fossil carbon, biogenic carbon and 17 substances (As, Ca, CaCO3, Cd, Cl, Cr, Cu, H, Hg, K, Mg, N, Ni, O, P, Pb, S, Zn) in a combined dry anaerobic digestion and post-composting facility were assessed. Mass balances showed good results with low uncertainties for non-volatile substances, while balances for nitrogen, carbon, volatile solids and total organic carbon showed larger but reasonable uncertainties, due to volatilisation and emissions into the air...
April 17, 2017: Waste Management
https://www.readbyqxmd.com/read/28427696/genetic-burden-of-ms-risk-variants-distinguish-patients-from-healthy-individuals-but-are-not-associated-with-disease-activity
#16
Helle Bach Søndergaard, Eva Rosa Petersen, Melinda Magyari, Finn Sellebjerg, Annette Bang Oturai
Weighted genetic risk score (wGRS) was analysed for association with disease activity in more than 500 MS patients before and during interferon-beta treatment. The wGRS was higher in MS patients than in healthy controls when analysing eight HLA - and 109 non-HLA MS risk gene variants. No significant associations were observed between number of relapses prior to or during treatment with interferon-beta, both with and without HLA risk alleles included in the wGRS. In conclusion, among Danes the wGRS was higher in MS patients than controls but was not associated with the overall disease activity or response to treatment with interferon-beta...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28427381/penicillin-treatment-for-patients-with-community-acquired-pneumonia-in-denmark-a-retrospective-cohort-study
#17
Gertrud Baunbæk Egelund, Andreas Vestergaard Jensen, Stine Bang Andersen, Pelle Trier Petersen, Bjarne Ørskov Lindhardt, Christian von Plessen, Gernot Rohde, Pernille Ravn
BACKGROUND: Community-acquired pneumonia (CAP) is a severe infection, with high mortality. Antibiotic strategies for CAP differ across Europe. The objective of the study was to describe the epidemiology of CAP in Denmark and evaluate the prognosis of patients empirically treated with penicillin-G/V monotherapy. METHODS: Retrospective cohort study including hospitalized patients with x-ray confirmed CAP. We calculated the population-based incidence, reviewed types of empiric antibiotics and duration of antibiotic treatment...
April 20, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28426945/testosterone-levels-in-healthy-men-correlate-negatively-with-serotonin-4-receptor-binding
#18
Erik Perfalk, Sofi da Cunha-Bang, Klaus K Holst, Sune Keller, Claus Svarer, Gitte M Knudsen, Vibe G Frokjaer
The serotonergic system integrates sex steroid information and plays a central role in mood and stress regulation, cognition, appetite and sleep. This interplay may be critical for likelihood of developing depressive episodes, at least in a subgroup of sensitive individuals. The serotonin 4 receptor (5-HT4R) indexes central serotonergic tonus, which may be related to endogenous sex-steroid levels in the mentally healthy state even though this remains elusive. Here we evaluate if peripheral levels of estradiol and testosterone are associated with 5-HT4R binding as imaged by [(11)C]SB207145 positron emission tomography in a group of 41 healthy men...
March 22, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28425826/lung-function-and-prevalence-of-respiratory-symptoms-in-norwegian-crab-processing-workers
#19
Marte R Thomassen, Lisbeth Aasmoe, Berit E Bang, Tonje Braaten
BACKGROUND: Seafood processing workers have an increased risk of developing occupational asthma. This has not been studied among Norwegian crab processing workers, nor has the respiratory health of exposed workers been compared to a control group. OBJECTIVES: Assessing the impact of working in the crab processing industry on workers' respiratory health. DESIGN: A cross-sectional study of the respiratory health in two types of crab processing workers compared to a control group...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28425620/periarticular-bone-loss-in-arthritis-is-induced-by-autoantibodies-against-citrullinated-vimentin
#20
Cecilia Engdahl, Holger Bang, Katharina Dietel, Stefanie C Lang, Ulrike Harre, Georg Schett
Periarticular bone loss is a long known but yet insufficiently understood phenomenon in patients with rheumatoid arthritis. This study investigated whether autoimmunity against citrullinated proteins is causally involved in triggering periarticular bone loss. Periarticular bone loss was studied in the standard antigen induced arthritis (AIA) mouse model with methylated bovine serum albumin (mBSA) as well as modified model with mutated citrullinated vimentin (MCV) alone or in combination with mBSA. Periarticular bone loss, subchondral osteoclastogenesis as well as local expression of cytokines, osteoclast genes and PAD enzymes were assessed after arthritis induction...
April 20, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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