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https://www.readbyqxmd.com/read/29667063/allocating-on-coal-consumption-and-co-2-emission-from-fair-and-efficient-perspective-empirical-analysis-on-provincial-panel-data-of-china
#1
Bang-Jun Wang, Jia-Lu Zhao, Yan-Fang Wu, Chao-Qun Zhu, Yin-Nan He, Yi-Xi Wei
This paper considers a problem of how to allocate resource effectively and equitably among provinces. To address the problem, a total factor resource input-oriented data envelopment analysis (DEA) model is used to evaluate the energy and environmental efficiency for 30 provinces in China during 2009-2013 in this paper. Based on the evaluation results, from efficient and fair perspective, a revised DEA-based resource allocation model is established. It is worth pointing out that the model takes the input orientation and output orientation into account at the same time and can be used to allocate coal consumption and carbon emission by 2020 for 30 provinces in China...
April 18, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29666524/comparison-of-high-pressure-and-high-temperature-short-time-processing-on-quality-of-carambola-juice-during-cold-storage
#2
Hsiao-Wen Huang, Bang-Yuan Chen, Chung-Yi Wang
This study validated high hydrostatic pressure processing (HPP) for achieving greater than 5-log reductions of Escherichia coli O157:H7 in carambola juice and determined shelf life of processed juice stored at 4 °C. Carambola juice processed at 600 MPa for 150 s was identified capable of achieving greater than 5.15-log reductions of E. coli O157:H7, and the quality was compared with that of high temperature short time (HTST)-pasteurized juice at 110 °C for 8.6 s. Aerobic, psychrotrophic, E. coli /coliform, and yeasts and moulds in the juice were reduced by HPP or HTST to levels below the minimum detection limit (< 1...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29665837/the-cxcl5-cxcr2-axis-contributes-to-the-epithelial-mesenchymal-transition-of-nasopharyngeal-carcinoma-cells-by-activating-erk-gsk-3%C3%AE-snail-signalling
#3
Wen-Ze Qiu, Hai-Bo Zhang, Wei-Xiong Xia, Liang-Ru Ke, Jing Yang, Ya-Hui Yu, Hu Liang, Xin-Jun Huang, Guo-Ying Liu, Wang-Zhong Li, Yan-Qun Xiang, Tie-Bang Kang, Xiang Guo, Xing Lv
BACKGROUND: Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis and prognosis, the molecular mechanisms of NPC development and progression remain unclear. METHODS: Quantitative RT-PCR (qRT-PCR), western blotting, cell growth, foci formation, migration and invasion assays, and xenograft mouse models were utilized to examine the expression levels and functions of the CXCL5/CXCR2 axis in NPC...
April 17, 2018: Journal of Experimental & Clinical Cancer Research: CR
https://www.readbyqxmd.com/read/29663652/a-longitudinal-study-of-serum-insulin-like-growth-factor-i-igf-i-levels-over-six-years-in-a-large-cohort-of-children-and-adolescents-with-type-1-diabetes-mellitus-a-marker-reflecting-diabetic-retinopathy
#4
Daniel Öberg, Jenny Salemyr, Eva Örtqvist, Anders Juul, Peter Bang
OBJECTIVE: To evaluate longitudinal serum IGF-I in a large cohort of children and adolescents with type 1 diabetes in relation to HbA1c, age, diabetes duration, and BMI, its association to height and retinopathy, and in comparison with healthy subject references. RESEARCH DESIGN AND METHODS: A total of 2,683 serum IGF-I values were obtained from 806 children and adolescents with T1DM, from annual blood samples for up to 6 consecutive years. RESULTS: In a multiple regression analysis IGF-I values were negatively correlated to HbA1c and diabetes duration, and positively correlated to BMI (p<0...
April 16, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29663322/quantitatively-characterizing-drug-induced-arrhythmic-contractile-motions-of-human-stem-cell-derived-cardiomyocytes
#5
Plansky Hoang, Nathaniel Huebsch, Shin Hyuk Bang, Brian A Siemons, Bruce R Conklin, Kevin E Healy, Zhen Ma, Sabir Jacquir
Quantification of abnormal contractile motions of cardiac tissue has been a noteworthy challenge and significant limitation in assessing and classifying the drug-induced arrhythmias (i.e. Torsades de pointes). To overcome these challenges, researchers have taken advantage of computational image processing tools to measure contractile motion from cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs). However, the amplitude and frequency analysis of contractile motion waveforms doesn't produce sufficient information to objectively classify the degree of variations between two or more sets of cardiac contractile motions...
April 16, 2018: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29661871/the-genetic-polymorphism-ugt1a4-3-is-associated-with-low-posaconazole-plasma-concentrations-in-hematological-malignancy-patients-receiving-the-oral-suspension
#6
Hyeon Jeong Suh, Seo Hyun Yoon, Kyung-Sang Yu, Joo-Youn Cho, Sang-In Park, Eunyoung Lee, Jeong-Ok Lee, Youngil Koh, Kyoung-Ho Song, Pyoeng Gyun Choe, Eu Suk Kim, Soo-Mee Bang, Hong Bin Kim, Inho Kim, Nam Joong Kim, Sang Hoon Song, Wan Beom Park, Myoung-Don Oh
The metabolism of posaconazole is mediated mainly by uridine 5' -diphospho-glucuronosyltransferase (UGT) enzymes, especially the UGT1A4. The aim of this study was to investigate the effects of genetic polymorphisms on the posaconazole plasma concentration (PPC). This prospective study was conducted from September 2014 to August 2016. We enrolled patients with acute myeloid leukemia or myelodysplastic syndrome treated with posaconazole oral suspension (200 mg) three times daily for fungal prophylaxis. The multi-drug resistance gene 1 3435C>T and 2677G>T/A variations, and UGT1A4*3 were examined by direct sequencing of DNA from peripheral whole blood samples...
April 16, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29661158/effect-of-an-intervention-targeting-inappropriate-continued-empirical-parenteral-vancomycin-use-a-quasi-experimental-study-in-a-region-of-high-mrsa-prevalence
#7
Pyoeng Gyun Choe, Hei Lim Koo, Doran Yoon, Ji Yun Bae, Eunyoung Lee, Joo-Hee Hwang, Kyoung-Ho Song, Wan Beom Park, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Myoung-Don Oh, Nam Joong Kim
BACKGROUND: Despite vancomycin use is a major risk factor for the emergence of vancomycin resistance, it is frequently inappropriately prescribed, especially as empirical treatment. We evaluated the effect of an antimicrobial stewardship intervention targeting for inappropriate continued empirical vancomycin use. METHODS: This was a quasi-experimental study comparing vancomycin use in a 6-month pre-intervention and 6-month intervention period. If empirical vancomycin was continued for more than 96 h without documentation of beta-lactam-resistant gram-positive microorganisms, it was considered inappropriate continued empirical vancomycin use...
April 16, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29660639/elevated-tumor-necrosis-factor-alpha-receptor-subtype-1-and-the-association-with-abnormal-brain-function-in-treatment-resistant-depression
#8
Mao-Hsuan Huang, Mu-Hong Chen, Pei-Chi Tu, Ya Mei Bai, Tung-Ping Su, Bang-Hung Yang, Ren-Shyan Liu, Cheng-Ta Li
BACKGROUND: Major depressive disorder (MDD) patients have shown elevated plasma levels of pro-inflammatory biomarkers compared to healthy controls. We hypothesized increased serum tumor necrosis factor-alpha receptor subtype 1 (TNF-α R1) is more associated with impaired brain function in patients with treatment-resistant depression (TRD) than those without TRD. METHODS: 34 MDD patients and 34 healthy subjects were recruited and we separated MDD patients to TRD group (n = 20) and non-TRD (n = 14) group...
April 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29660462/anti-helicobacterpylori-effectiveness-and-targeted-delivery-performance-of-amoxicillin-uccs-2-tpp-nanoparticles-based-on-ureido-modified-chitosan-derivative
#9
Zi-Wei Jing, Min Luo, Yi-Yang Jia, Chen Li, Si-Yuan Zhou, Qi-Bing Mei, Bang-Le Zhang
The amoxicillin-UCCs-2/TPP nanoparticles constructed with ureido-modified chitosan derivative UCCs-2 and sodium tripolyphosphate (TPP) played an important role to deliver drug to achieve more efficacious and specific eradication of Helicobacterpylori (H. pylori) in vitro. In this study, the anti-H. pylori effectiveness in vivo and uptake mechanism was investigated in details, including the effect of temperature, pH values and the addition of competitive substrate urea on uptake. Compared with unmodified nanoparticles, a more efficacious and specific anti-H...
April 13, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29659832/average-sperm-count-remains-unchanged-despite-reduction-in-maternal-smoking-results-from-a-large-cross-sectional-study-with-annual-investigations-over-21-years
#10
L Priskorn, L Nordkap, A K Bang, M Krause, S A Holmboe, D L Egeberg Palme, S B Winge, N Mørup, E Carlsen, U N Joensen, M Blomberg Jensen, K M Main, A Juul, N E Skakkebaek, T K Jensen, N Jørgensen
STUDY QUESTION: How are temporal trends in lifestyle factors, including exposure to maternal smoking in utero, associated to semen quality in young men from the general population? SUMMARY ANSWER: Exposure to maternal smoking was associated with lower sperm counts but no overall increase in sperm counts was observed during the study period despite a decrease in this exposure. WHAT IS KNOWN ALREADY: Meta-analyses suggest a continuous decline in semen quality but few studies have investigated temporal trends in unselected populations recruited and analysed with the same protocol over a long period and none have studied simultaneous trends in lifestyle factors...
April 11, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29659804/high-content-screen-for-modifiers-of-niemann-pick-type-c-disease-in-patient-cells
#11
Emily K Pugach, McKenna Feltes, Randal J Kaufman, Daniel S Ory, Anne G Bang
Niemann-Pick type C disease (NPC) is a rare lysosomal storage disease caused primarily by mutations in NPC1. NPC1 encodes the lysosomal cholesterol transport protein NPC1. The most common NPC1 mutation is a missense mutation (NPC1I1061T) that causes misfolding and rapid degradation of mutant protein in the endoplasmic reticulum. Cholesterol accumulates in enlarged lysosomes as a result of decreased levels of lysosomal NPC1I1061T protein in patient cells. There is currently no cure or FDA-approved treatment for patients...
April 12, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29652476/super-tough-ultra-stretchable-hydrogel-with-multi-stimuli-responsiveness
#12
Meng-Meng Song, Ya-Min Wang, Bing Wang, Xiang-Yong Liang, Zhi-Yi Chang, Bang-Jing Li, Sheng Zhang
The research of hydrogel has been increasingly focused on designing effective energy dissipation structure in recent years. Here, we report a kind of novel supramolecular crosslinkers, which formed by self-assembling amphiphilic block copolymers with guest groups at the end and vinyl functionalized cyclodextrin (CD) through host guest interaction. These crosslinkers could dissipate energy effectively since they combined multiple sacrificial mechanisms across multi-scales through physical interactions. The resulted hydrogel shows distinguishing mechanical properties (fracture toughness of 2...
April 13, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29651648/body-mass-index-and-mortality-in-patients-with-gastric-cancer-a-large-cohort-study
#13
Jung Hwan Lee, Boram Park, Jungnam Joo, Myeong-Cherl Kook, Young-Il Kim, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu, Young-Woo Kim, Soo-Jeong Cho
BACKGROUND: The effects of obesity on prognosis in gastric cancer are controversial. AIMS: To evaluate the association between body mass index (BMI) and mortality in patients with gastric cancer. METHODS: A single-institution cohort of 7765 patients with gastric cancer undergoing curative gastrectomy between October 2000 and June 2016 was categorized into six groups based on BMI: underweight (< 18.5 kg/m2 ), normal (18.5 to < 23 kg/m2 ), overweight (23 to < 25 kg/m2 ), mildly obese (25 to < 28 kg/m2 ), moderately obese (28 to < 30 kg/m2 ), and severely obese (≥ 30 kg/m2 )...
April 12, 2018: Gastric Cancer
https://www.readbyqxmd.com/read/29649042/factors-associated-with-the-benefits-of-concurrent-administration-of-intratympanic-steroid-injection-with-oral-steroids-in-patients-with-acute-acoustic-trauma
#14
Young-Soo Chang, Kanghyun Bang, Nayeon Choi, Jong Sei Kim, Gang-Gyu Lee
OBJECTIVE: To analyze the factors associated with the benefits of concurrent administration of intratympanic steroid injection (ITSI) and oral steroids in patients with acute acoustic trauma (AAT) incurred during military training. STUDY DESIGN: Retrospective analysis. PATIENTS: Nineteen patients eligible under the criteria established concerning treatment for AAT were retrospectively reviewed in this study. INTERVENTIONS: ITSI treatments were administered simultaneously alongside oral prednisolone...
April 11, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29644628/quantitatively-characterizing-drug-induced-arrhythmic-contractile-motions-of-human-stem-cell-derived-cardiomyocytes
#15
Plansky Hoang, Nathaniel Huebsch, Shin Hyuk Bang, Brian A Siemons, Bruce R Conklin, Kevin E Healy, Zhen Ma, Sabir Jacquir
Quantification of abnormal contractile motions of cardiac tissue has been a noteworthy challenge and significant limitation in assessing and classifying the drug-induced arrhythmias (i.e. Torsades de pointes). To overcome these challenges, researchers have taken advantage of computational image processing tools to measure contractile motion from cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs). However, the amplitude and frequency analysis of contractile motion waveforms doesn't produce sufficient information to objectively classify the degree of variations between two or more sets of cardiac contractile motions...
April 12, 2018: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29643710/positive-correlation-of-serum-leptin-levels-and-peripheral-arterial-stiffness-in-patients-with-type-2-diabetes
#16
Chia-Wen Lu, Chung-Jen Lee, Jia-Sian Hou, Du-An Wu, Bang-Gee Hsu
Objective: Leptin plays a pathophysiologic role in the pathogenesis of aortic dysfunction and peripheral arterial stiffness (PAS). Our aim was to evaluate the risk factors for developing PAS and the association of leptin and PAS in patients with type 2 diabetes mellitus (DM). Materials and Methods: Fasting blood samples were obtained for biochemical data and leptin determinations from 105 patients with type 2 DM. In this study, we applied an automatic pulse wave analyzer (VaSera VS-1000) to measure the brachial-ankle pulse wave velocity (baPWV); a baPWV value >14...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29643431/an-estradiol-independent-bdnf-npy-cascade-is-involved-in-the-antidepressant-effect-of-mechanical-acupuncture-instruments-in-ovariectomized-rats
#17
Su Yeon Seo, Ji-Young Moon, Suk-Yun Kang, O Sang Kwon, Sunoh Kwon, Se Kyun Bang, Soo Phil Kim, Kwang-Ho Choi, Yeonhee Ryu
Menopause-related depression devastates women's quality of life after middle age. Previous research has shown that estrogen hormone therapy has serious adverse effects; thus, complementary and integrative therapies have been considered clinically. The present study investigates whether stimulation of an acupoint using a mechanical acupuncture instrument (MAI) can mitigate depression-like behavior caused by estrogen deficiency in ovariectomized (OVX) rats. The animals were divided into Sham OVX, OVX, OVX + Sameumgyo (SP6) and OVX + NonAcu (non-acupuncture point) groups...
April 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29629222/survival-benefit-of-perioperative-chemotherapy-in-patients-with-locally-advanced-gastric-cancer-a-propensity-score-matched-analysis
#18
Bang Wool Eom, Sohee Kim, Ja Yeon Kim, Hong Man Yoon, Mi-Jung Kim, Byung-Ho Nam, Young-Woo Kim, Young-Iee Park, Sook Ryun Park, Keun Won Ryu
Purpose: It has been reported that the survival of patients with locally advanced gastric cancer (LAGC) is better in East Asia countries than in developed western countries; however, the prognosis of LAGC remains poor. This study aimed to evaluate the effects of perioperative chemotherapy on the long-term survival of East Asia patients with LAGC. Materials and Methods: From October 2006 through August 2008, 43 patients with LAGC received perioperative S-1 combined with weekly docetaxel in a phase II study (neoadjuvant group)...
March 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29629218/safety-of-laparoscopic-sentinel-basin-dissection-in-patients-with-gastric-cancer-an-analysis-from-the-senorita-prospective-multicenter-quality-control-trial
#19
Ji Yeong An, Jae Seok Min, Young Joon Lee, Sang Ho Jeong, Hoon Hur, Sang Uk Han, Woo Jin Hyung, Gyu Seok Cho, Gui Ae Jeong, Oh Jeong, Young Kyu Park, Mi Ran Jung, Ji Yeon Park, Young Woo Kim, Hong Man Yoon, Bang Wool Eom, Keun Won Ryu
Purpose: We investigated complications after laparoscopic sentinel basin dissection (SBD) for patients with gastric cancer who were enrolled in a quality control study, prior to the phase III trial of sentinel lymph node navigation surgery (SNNS). Materials and Methods: We analyzed prospective data from a Korean multicenter prerequisite quality control trial of laparoscopic SBD for gastric cancer and assessed procedure-related and surgical complications. All complications were classified according to the Clavien-Dindo Classification (CDC) system and were compared with the results of the previously published SNNS trial...
March 2018: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29628466/increase-carotid-flow-by-double-sheath-connection-technique-to-reduce-cerebral-ischemia-for-transcatheter-aortic-valve-implantation-through-transcarotid-approach
#20
Richard Tsai, I-Ming Chen, Po-Lin Chen, Hsin-Bang Leu, Ying-Hwa Chen, Hsiao-Huang Chang
PURPOSE: Transcarotid transcatheter aortic valve implantation (TAVI) is one alternative approach if unfavorable femoral access. However, this approach may cause cerebral vascular accidents (CVAs) by temporarily occluding common carotid artery (CCA). The purpose of this study is to develop a new method reducing cerebral ischemia during transcarotid TAVI. METHODS: We inserted an 8- and 18-Fr. sheath in CCA with tip toward brain and aortic arch, respectively, and connected their side arms to create a bypass flow...
April 6, 2018: Annals of Thoracic and Cardiovascular Surgery
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