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https://www.readbyqxmd.com/read/29045978/-clinicopathologic-features-of-infant-dysembryoplastic-neuroepithelial-tumor-a-case-report-and-literature-review
#1
H Wang, J T Ye, H X Yao, D Li, Y Dong
Dysembryoplastic neuroepithelial tumor (DNT) has traditionally been viewed as rare benign tumors that present with seizure widely considered curable with surgery alone. Most DNTs occur in childhood and young adults. However, rare reported cases occur in infants. This paper reported an infant case of DNT and its diagnosis, differential diagnosis, treatment, molecular features and prognosis based on the review of current literatures. The age onset of this patient was only 11 months old. The clinical manifestations were partial seizures and the imaging data untypical; CT and MRI were all supportive of astrocytoma...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29043942/the-librarian-s-contribution-to-continuing-medical-education
#2
Andrew L Gerber
At many hospitals, including Robert Wood Johnson (RWJ) University Hospital Rahway, librarians facilitate continuing medical education (CME) programs, sometimes working in that capacity as much as in their traditional librarian functions such as reference, research, cataloging, and bibliographic instruction. This column traces the relationship between the two aspects of the RWJ Rahway's CME coordinator and health sciences librarian's job to demonstrate that, because of their duties and skills, medical librarians can meaningfully contribute to hospitals' CME programs...
October 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/29043858/melanoma-segmentation-based-on-deep-learning
#3
Xiaoqing Zhang
Malignant melanoma is one of the most deadly forms of skin cancer, which is one of the world's fastest-growing cancers. Early diagnosis and treatment is critical. In this study, a neural network structure is utilized to construct a broad and accurate basis for the diagnosis of skin cancer, thereby reducing screening errors. The technique is able to improve the efficacy for identification of normally indistinguishable lesions (such as pigment spots) versus clinically unknown lesions, and to ultimately improve the diagnostic accuracy...
October 18, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/29043155/catatonia-as-a-putative-nosological-entity-a-historical-sketch
#4
REVIEW
Gábor Gazdag, Rozalia Takács, Gabor S Ungvari
Kahlbaum was the first to propose catatonia as a separate disease following the example of general paresis of the insane, which served as a model for establishing a nosological entity. However, Kahlbaum was uncertain about the nosological position of catatonia and considered it a syndrome, or "a temporary stage or a part of a complex picture of various disease forms". Until recently, the issue of catatonia as a separate diagnostic category was not entertained, mainly due to a misinterpretation of Kraepelin's influential views on catatonia as a subtype of schizophrenia...
September 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/29041954/combined-cognitive-and-vocational-interventions-after-mild-to-moderate-traumatic-brain-injury-study-protocol-for-a-randomized-controlled-trial
#5
Emilie I Howe, Knut-Petter S Langlo, Hans Christoffer Aargaard Terjesen, Cecilie Røe, Anne-Kristine Schanke, Helene L Søberg, Unni Sveen, Eline Aas, Heidi Enehaug, Daniele E Alves, Pål Klethagen, Kjersti Sagstad, Christine M Moen, Karin Torsteinsbrend, Anne-Margrethe Linnestad, Tonje Haug Nordenmark, Birte Sand Rismyhr, Grete Wangen, Juan Lu, Jennie Ponsford, Elizabeth W Twamley, Helene Ugelstad, Øystein Spjelkavik, Marianne Løvstad, Nada Andelic
BACKGROUND: A considerable proportion of patients with mild to moderate traumatic brain injury (TBI) experience long-lasting somatic, cognitive, and emotional symptoms that may hamper their capacity to return to work (RTW). Although several studies have described medical, psychological, and work-related factors that predict RTW after TBI, well-controlled intervention studies regarding RTW are scarce. Furthermore, there has traditionally been weak collaboration among health-related rehabilitation services, the labor and welfare sector, and workplaces...
October 17, 2017: Trials
https://www.readbyqxmd.com/read/29041800/an-exploration-of-the-knowledge-attitudes-and-beliefs-of-xhosa-men-concerning-traditional-circumcision
#6
Salome Froneman, Paul A Kapp
BACKGROUND: The practice of traditional circumcision is associated with considerable morbidity and mortality, yet there is a paucity of literature that provides an understanding of the cultural values that influence men to choose traditional rather than medical circumcision.The aim of this study was to better understand the culture surrounding traditional circumcision, with a view to addressing morbidity and mortality rates associated with the Xhosa male initiation rituals.We explored Xhosa men's perceptions regarding the need for the risks and the social pressure to undergo traditional circumcision, the impact of non-initiation or failed initiation and the perceived barriers to obtaining medical help for the complications of traditional circumcisions...
October 13, 2017: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29041245/frequency-constrained-robust-principal-component-analysis-a-sparse-representation-approach-to-segmentation-of-dynamic-features-in-optical-coherence-tomography-imaging
#7
James P McLean, Yuye Ling, Christine P Hendon
Sparse representation theory is an exciting area of research with recent applications in medical imaging and detection, segmentation, and quantitative analysis of biological processes. We present a variant on the robust-principal component analysis (RPCA) algorithm, called frequency constrained RPCA (FC-RPCA), for selectively segmenting dynamic phenomena that exhibit spectra within a user-defined range of frequencies. The algorithm lacks subjective parameter tuning and demonstrates robust segmentation in datasets containing multiple motion sources and high amplitude noise...
October 16, 2017: Optics Express
https://www.readbyqxmd.com/read/29039720/trends-in-the-contribution-of-emergency-departments-to-the-provision-of-health-care-in-the-usa
#8
David Marcozzi, Brendan Carr, Alisha Liferidge, Nicole Baehr, Brian Browne
Traditional approaches to assessing the health of populations focus on the use of primary care and the delivery of care through patient-centered homes, managed care resources, and accountable care organizations. The use of emergency departments (EDs) has largely not been given consideration in these models. Our study aimed to determine the contribution of EDs to the health care received by Americans between 1996 and 2010 and to compare it with the contribution of outpatient and inpatient services using National Ambulatory Medical Care Survey and National Hospital Discharge Survey databases...
January 1, 2017: International Journal of Health Services: Planning, Administration, Evaluation
https://www.readbyqxmd.com/read/29039627/beliefs-endorsement-and-application-of-homeopathy-disclosed-a-survey-among-ambulatory-care-physicians
#9
Stefan Markun, Marc Maeder, Thomas Rosemann, Sima Djalali
BACKGROUND: Explanation models for the effectiveness of homeopathy are not supported by natural sciences and the aggregated evidence from clinical trials is unconvincing. From this standpoint, placebo effects seem the most obvious explanation for the therapeutic effects experienced in homeopathy. Still, many physicians continue to prescribe homeopathic treatments. OBJECTIVES: Whether physicians who prescribe homeopathic treatments aim to achieve placebo effects or actually believe in specific effects is poorly understood...
October 17, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29039378/dna-encoding-training-using-3d-gesture-interaction
#10
Stelian Nicola, Flavia-Laura Handrea, Mihaela Crişan-Vida, Lăcrămioara Stoicu-Tivadar
The work described in this paper summarizes the development process and presents the results of a human genetics training application, studying the 20 amino acids formed by the combination of the 3 nucleotides of DNA targeting mainly medical and bioinformatics students. Currently, the domain applications using recognized human gestures of the Leap Motion sensor are used in molecules controlling and learning from Mendeleev table or in visualizing the animated reactions of specific molecules with water. The novelty in the current application consists in using the Leap Motion sensor creating new gestures for the application control and creating a tag based algorithm corresponding to each amino acid, depending on the position in the 3D virtual space of the 4 nucleotides of DNA and their type...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29039151/-pain-experience-of-nursing-students-and-the-methods-used-to-cope-with-pain
#11
Tuğba Uzunçakmak, Mahmut Kılıç
OBJECTIVES: This study aimed to determine the pain experience of nursing students and the methods used to cope with it. METHODS: This descriptive study was conducted at the nursing department. Sampling was not used. The study was completed with 264 students. Data were collected using the questionnaire that was prepared by the researchers. Descriptive statistics and chi-square test were used for data analysis. RESULTS: Of all students, 76.1% (84...
July 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29039094/immunoelectron-microscopy-for-visualization-of-nanoparticles
#12
Sarah R Anderson, David Parmiter, Ulrich Baxa, Kunio Nagashima
Immunoelectron microscopy (IEM) on a solid phase such as a carbon film is a fast and powerful way to detect and visualize surface antigens on nanoparticles by using a transmission electron microscope (TEM). Nanoparticles, in particular ones for medical applications, are often modified on the surface with soft materials to make them more soluble, less toxic, or targetable to cancerous tumors. Imaging the soft material on the surface of solid nanoparticles by electron microscopy is often a challenge. IEM can overcome this issue in cases where antibodies to any of the surface material are available, which is often the case for proteins, but also for commonly used materials such as polyethylene glycol (PEG)...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29038702/the-effect-of-teucrium-polium-on-the-duration-of-menstrual-bleeding-a-triple-blind-placebo-controlled-clinical-trial
#13
Abadian Khadige, Zohre Keshavarz, Faraz Mojab, Hamid Alavi Majd
BACKGROUND: Teucrium polium (T. polium; locally called 'kalpooreh') is a herbal medicine with therapeutic effects against diabetes and fungal infections, and it has analgesic and anti-inflammatory effects as well. It is also used traditionally as a remedy in treating headache, dysmenorrhea, convulsions and gastrointestinal disorders. Moreover, its hypoglycemic, hypolipidemic and antibacterial effects have been reported in recent studies. OBJECTIVE: To compare the effectiveness of T...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29038378/current-status-and-future-challenges-for-molecular-imaging
#14
REVIEW
Carolyn J Anderson, Jason S Lewis
Molecular imaging (MI), used in its wider sense of biology at the molecular level, is a field that lies at the intersection of molecular biology and traditional medical imaging. As advances in medicine have exponentially expanded over the last few decades, so has our need to better understand the fundamental behaviour of living organisms in a non-invasive and timely manner. This commentary draws from topics the authors addressed in their presentations at the 2017 Royal Society Meeting 'Challenges for chemistry in molecular imaging', as well as a discussion of where MI is today and where it is heading in the future...
November 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29038075/biochemical-marker-discovery-testing-and-evaluation-for-facilitating-oa-drug-discovery-and-development
#15
REVIEW
Anne-Christine Bay-Jensen, Christian S Thudium, Oreste Gualillo, Ali Mobasheri
Osteoarthritis (OA) is the most common form of joint disease. This presents the OA research community and pharmaceutical companies developing disease-modifying OA drugs (DMOADs) with great opportunities. The different OA subtypes complicate the traditional approaches for developing new treatments. If we can identify new markers that can distinguish different subtypes this could greatly facilitate drug development from early discovery to late clinical development. Nevertheless, the current approaches result in poorly targeted treatments and the inability to recruit the right patients for clinical trials...
October 13, 2017: Drug Discovery Today
https://www.readbyqxmd.com/read/29037823/the-development-of-a-novel-perfused-cadaver-model-with-dynamic-vital-sign-regulation-and-real-world-scenarios-to-teach-surgical-skills-and-error-management
#16
Michael Minneti, Craig J Baker, Maura E Sullivan
The landscape of graduate medical education has changed dramatically over the past decade and the traditional apprenticeship model has undergone scrutiny and modifications. The mandate of the 80-hour work-week, the introduction of integrated residency programs, increased global awareness about patient safety along with financial constraints have spurred changes in graduate educational practices. In addition, new technologies, more complex procedures, and a host of external constraints have changed where and how we teach technical and procedural skills...
October 13, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29037269/prevalence-of-prediabetes-and-modifiable-factors-in-an-ethnic-group-of-mexico-the-comc%C3%A3-ac-project
#17
Monica Daniela Robles-Ordaz, Ana Cristina Gallegos-Aguilar, Rene Urquidez-Romero, Rolando Giovanni Diaz-Zavala, Marcos Gerardo Lavandera-Torres, Julian Esparza-Romero
OBJECTIVE: To determine the prevalence of and modifiable factors associated with prediabetes in the Comcáac Indians. DESIGN: Cross-sectional study where prediabetes was defined using fasting plasma glucose, 2 h plasma glucose and glycated Hb (HbA1c). Physical, anthropometric and biochemical measurements, medical record, socio-economic, dietary and physical activity information were collected. The modifiable factors associated with prediabetes were assessed using multiple logistic regression...
October 17, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29036879/enhancement-of-digital-radiography-image-quality-using-a-convolutional-neural-network
#18
Yuewen Sun, Litao Li, Peng Cong, Zhentao Wang, Xiaojing Guo
Digital radiography system is widely used for noninvasive security check and medical imaging examination. However, the system has a limitation of lower image quality in spatial resolution and signal to noise ratio. In this study, we explored whether the image quality acquired by the digital radiography system can be improved with a modified convolutional neural network to generate high-resolution images with reduced noise from the original low-quality images. The experiment evaluated on a test dataset, which contains 5 X-ray images, showed that the proposed method outperformed the traditional methods (i...
October 10, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29036366/accounting-for-selectivity-bias-and-correlation-across-the-sequence-from-elevated-blood-pressure-to-hypertension-diagnosis-and-treatment
#19
Penny Gordon-Larsen, Samantha M Attard, Annie Green Howard, Barry M Popkin, Bing Zhang, Shufa Du, David K Guilkey
BACKGROUND: It is unknown whether efforts to reduce hypertension burden in countries with very high prevalence, would be more effective if directed at hypertension diagnosis vs. treatment. Most analyses do not address bias and correlation across the sequence from elevated blood pressure (BP) to hypertension diagnosis and treatment, leading to potentially misleading findings. METHODS: Using data spanning 18 years of the China Health and Nutrition Survey (n = 18,926; ages 18-75 years), we used an innovative 3-step, integrated system of equations to predict the sequence from: (i) elevated BP (systolic/diastolic BP ≥ 140/90 mm Hg) to (ii) diagnosed hypertension conditional on elevated BP, and to (iii) treatment (medication use) conditional on diagnosis, accounting for measured and unmeasured individual- and community-level confounders at each of the 3 steps...
September 26, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/29036011/evaluating-the-impact-of-prescription-fill-rates-on-risk-stratification-model-performance
#20
Hsien-Yen Chang, Thomas M Richards, Kenneth M Shermock, Stacy Elder Dalpoas, Hong J Kan, G Caleb Alexander, Jonathan P Weiner, Hadi Kharrazi
BACKGROUND: Risk adjustment models are traditionally derived from administrative claims. Prescription fill rates-extracted by comparing electronic health record prescriptions and pharmacy claims fills-represent a novel measure of medication adherence and may improve the performance of risk adjustment models. OBJECTIVE: We evaluated the impact of prescription fill rates on claims-based risk adjustment models in predicting both concurrent and prospective costs and utilization...
October 13, 2017: Medical Care
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