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https://www.readbyqxmd.com/read/29925068/improving-global-kidney-health-international-society-of-nephrology-initiatives-and-the-global-kidney-health-atlas
#1
Adeera Levin
BACKGROUND: Chronic Kidney Disease (CKD) is a major public health problem and is increasingly being recognized as an important driver of costs in all health care systems. The diversity of outcomes for people living with CKD is in part due to variability in biology, access to care, environmental factors, and health care system differences. The International Society of Nephrology (ISN), working in collaboration with its partners, has evolved into a philanthropic organization, from a traditional medical society, committed to a vision that sees "a future where all people have access to sustainable kidney health"...
2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29924801/the-time-has-come-to-eliminate-the-gaps-in-the-under-recognized-burden-of-elder-mistreatment-a-community-based-cross-sectional-study-from-rural-eastern-nepal
#2
Uday Narayan Yadav, Man Kumar Tamang, Grish Paudel, Bharat Kafle, Suresh Mehta, Varalakshmi Chandra Sekaran, Jeroen R J H Gruiskens
BACKGROUND: Elder mistreatment is a well-recognized public health issue with complex underlying factors. The current study hypothesized that there is no effect of any of the following factors on any type of elder mistreatment: ethnicity, age group, education status, gender, living arrangement, concentration problems, medication for any disease, income level of caregiver, use of alcohol and tobacco products, and dependence on family or caregivers for daily activities. MATERIALS AND METHODS: We conducted a cross-sectional study of 339 elders adults aged 60 or above residing in a rural part of eastern Nepal between August and November 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29924736/how-common-are-cognitive-errors-in-cases-presented-at-emergency-medicine-resident-morbidity-and-mortality-conferences
#3
David Chu, Jane Xiao, Payal Shah, Brett Todd
BACKGROUND: Cognitive errors are a major contributor to medical error. Traditionally, medical errors at teaching hospitals are analyzed in morbidity and mortality (M&M) conferences. We aimed to describe the frequency of cognitive errors in relation to the occurrence of diagnostic and other error types, in cases presented at an emergency medicine (EM) resident M&M conference. METHODS: We conducted a retrospective study of all cases presented at a suburban US EM residency monthly M&M conference from September 2011 to August 2016...
June 20, 2018: Diagnosis
https://www.readbyqxmd.com/read/29924421/description-and-preliminary-outcomes-of-an-in-vivo-exposure-group-treatment-for-posttraumatic-stress-disorder
#4
Eliora Porter, Erin G Romero, Melissa D Barone
Prolonged exposure (PE) therapy is traditionally delivered individually to patients. To engage more veterans in care, an in vivo exposure group treatment was developed in an urban VA medical center. This treatment represented a modification of the in vivo exposure portion of PE, with the addition of in-session, therapist-assisted in vivo exposures. Here, we describe this 12-week treatment and present preliminary outcome data. Demographics and pre- and posttreatment scores on the PTSD Checklist-Specific (PCL-S) and Beck Depression Inventory-II (BDI-II) were extracted from a program evaluation database...
June 20, 2018: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29924284/-cultural-practices-linked-to-health-care-and-perception-on-the-attention-health-facilities-in-residents-of-highandean-settlements-in-huancavelica-peru
#5
Félix Valenzuela-Oré, Franco Romaní-Romaní, Betty M Monteza-Facho, Duilio Fuentes-Delgado, Enma Vilchez-Buitron, Oswaldo Salaverry-García
Inequalities in terms of access and quality of healthcare persist, especially among Andean populations, such as the community of Chopcca. Here, we describe the perception of healthcare provided in medical facilities as well as the practices linked to health care in residents of settlements in the Huancavelica region. We carried out a cross-sectional study by means of a structured questionnaire administered to 775 residents of urban and rural towns of the Yauli and Paucará districts. 68.7% refer always using medicinal plants to cure themselves; 86...
January 2018: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29924041/safety-and-efficacy-of-galgeun-tang-ga-cheongung-sinyi-a-herbal-formula-for-the-treatment-of-chronic-rhinosinusitis-a-study-protocol-for-a-randomized-controlled-trial
#6
Mi Ju Son, Ojin Kwon, Sungha Kim, Young-Eun Kim, So Young Jung, Bo-Young Kim, Jeong In Kang, Jun-Hwan Lee, Dong-Hyo Lee
INTRODUCTION: A herbal formula, Galgeun-tang-ga-cheongung-sinyi (GGTCS), is traditionally used for the treatment of rhinosinusitis in East Asian countries. However, there is a dearth of clinical evidence supporting the effects of this medication. Here, we describe the protocol for a randomized controlled study designed to investigate the efficacy and safety of GGTCS for the treatment of chronic rhinosinusitis (CRS). METHODS AND ANALYSIS: To investigate the clinical efficacy and safety of GGTCS for the treatment of CRS, a randomized, double-blind, placebo-controlled, parallel group, clinical trial has been designed...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923966/efficacy-and-safety-of-immunosuppressive-agents-for-thyroid-eye-disease
#7
Diego Strianese
PURPOSE: To present an update on the efficacy and safety of immunosuppressive therapy for thyroid eye disease (TED) and to offer a general recommendation for management of TED, in light of these reports. METHODS: Data were retrieved from a literature search on PubMed, using the following words: thyroid eye disease, immunosuppressant, corticosteroid, methotrexate, azathioprine, cyclosporine, cyclophosphamide, rituximab, etanercept, adalimumab, tocilizumab, teprotumumab, adverse effects, side effects, and complications...
June 18, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29922850/safety-of-orogastric-tubes-in-foregut-and-bariatric-surgery
#8
Kulvir Nandra, Richard Ing
BACKGROUND: Orogastric tubes have traditionally aided foregut procedures with sizing and organ protection. The rise of bariatric surgery has led to the creation of novel medical devices aimed at facilitating the laparoscopic sleeve gastrectomy. While approved by the FDA, the long-term safety profile of these devices in the general population is often unknown. This review looks at complications associated with novel Orogastric Tubes compared to the traditional bougie. METHODS: We performed a review of the Food and Drug Administration's (FDA) Manufacturer and User Facility Device Experience (MAUDE) database for complications associated with the traditional bougie, Boehringer Labs ViSiGi 3D® and the Medtronic GastriSail™ since 2011...
June 19, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29922065/current-treatment-options-for-psoriatic-arthritis-spotlight-on-abatacept
#9
REVIEW
Francesco Ursini, Emilio Russo, Roberto De Giorgio, Giovambattista De Sarro, Salvatore D'Angelo
Psoriatic arthritis (PsA) is a chronic inflammatory disease of joints, tendon sheaths, and entheses affecting patients with established skin psoriasis, or, less frequently, patients without a personal history of psoriasis with a positive familial history. Many treatment options are now available to deal with the different aspects of the disease, including traditional and biological disease-modifying antirheumatic drugs and the recently released targeted synthetic disease-modifying antirheumatic drugs. However, ~40% of patients still fail to achieve a meaningful clinical response to first-line biologic therapy advocating the development of novel medications...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29921575/shen-shuai-ning-granule-decreased-serum-concentrations-of-indoxyl-sulfate-in-uremic-patients-undergoing-peritoneal-dialysis
#10
Xujiao Chen, Shouhong Gao, Mengna Ruan, Sixiu Chen, Jing Xu, Xiaohong Xing, Xiaohong Pan, Changlin Mei, Zhiguo Mao
Background Clearance of protein-bound uremic toxins (PBUTs) by dialysis is a challenge in the treatment of uremic patients. Shen-Shuai-Ning(SSN), a traditional Chinese medicine formulation, has been used commonly in China to retard kidney disease progression and decrease uremic toxins in chronic kidney disease patients, but the effects of SSN on serum PBUTs in dialysis patients were not investigated. Methods We conducted a randomized controlled trial in patients on peritoneal dialysis (PD) at dialysis center of Changzheng Hospital to evaluate the effects of SSN on serum PBUTs...
June 19, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29921253/assessment-of-a-block-curriculum-design-on-medical-postgraduates-perception-towards-biostatistics-a-cohort-study
#11
Chen Li, Ling Wang, Yuhai Zhang, Chanjuan Li, Yongyong Xu, Lei Shang, Jielai Xia
BACKGROUND: Biostatistics is a key but challenging subject in medical curricula that is usually delivered via a didactic approach in China. However, whether it is the best teaching approach to improve the learner's competency, especially for medical postgraduates is yet to be proved. Therefore, a block curriculum design was initially developed to provide selective education to the postgraduates towards the professional career of their interest. A questionnaire was designed to assess the students' perceptions toward biostatistics as these affective factors might impact the learning process...
June 19, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29920473/cystinyl-and-pyroglutamyl-beta-naphthylamide-hydrolyzing-activities-are-modified-coordinately-between-hypothalamus-liver-and-plasma-depending-on-the-thyroid-status-of-adult-male-rats
#12
A B Segarra, I Prieto, M Martinez-Canamero, F Vargas, M De Gasparo, P Vanderheyden, S Zorad, M Ramirez-Sanchez
Stem cells constitute a non-specialised cell pool able for proliferation, self-renewal and differentiation into progeny constantly replacing used up tissue and/or organ fragments. They have been observed to be present in many tissue reservoirs, including stomatognathic system. Oral cavity seems to be a particularly attractive stem cells' source as these cells are richly present and easily accessible in dental and periodontal tissues and they can be used for therapeutic purposes. Their application is also morally and ethically non-controversial...
April 2018: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/29916841/assessing-the-effectiveness-of-problem-based-learning-as-a-new-approach-on-health-care-provider-ethical-reasoning-development-in-shiraz-university-of-medical-sciences
#13
Leila Bazrafcan, Farnaz Takmil, Nasrin Shokrpour
Problem-based learning (PBL) has become a distinct approach in learning. To assess the effectiveness of PBL in teaching ethics to medical students and the effect it has on their ethical reasoning, we decided to hold a PBL ethics workshop and then evaluate them based on pretest and posttest. This quasi-experimental comparative study in Shiraz University of Medical Sciences was designed based on pretest-posttest nonequivalent groups. After obtaining their consent, 120 health care providers were randomly selected and assigned in 4 groups and then asked to attend the ethics workshop...
June 18, 2018: Health Care Manager
https://www.readbyqxmd.com/read/29916603/-oncological-disease-dimensions-of-the-phenomenon-and-role-ionizing-radiation
#14
Giuseppe Taino, Lorenzo Bordini, Marcello Imbriani
OBJECTIVES: The continuous scientific advances against neoplastic diseases affecting all areas of oncology biomedical research. Age is an extremely important factor in cancer development, since the incidence of cancer increases significantly with age. Because of aging of the Italian population, although the incidence is kept constant, the number of cancer diagnosis is inevitably going to increase over time only to increasing age. METHODS: Survival after the diagnosis of cancer is one of the main indicators that allow to evaluate the effectiveness of the health system against the cancer disease...
November 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29916589/-the-multidimensional-concept-of-health-and-the-gender-category-theoretical-and-practical-perspectives
#15
Rita Biancheri
OBJECTIVES: This paper will examine the difficulties encountered in the bio-medical approach adopted to understand the psycho-social needs present in the clinical observation of a diseased body to the treatment of the person. METHODS: Traditional interpretation tools are not sufficient to comprehend the complexity of the factors involved in prevention processes, and the risk is that the introduction of new approaches will be delayed. Knowledge is an interactive, communicative and social process, meaning our focus shifts from the things we see to the way we see them, only to see what we don't normally see...
November 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29916399/photon-energy-readings-in-osl-dosimeter-filters-an-application-to-retrospective-dose-estimation-for-nuclear-medicine-workers
#16
Daphnée Villoing, Cari M Kitahara, Christopher Passmore, Steven L Simon, R Craig Yoder
This work investigates the applicability of using data from personal monitoring dosimeters to assess photon energies to which medical workers were exposed. Such determinations would be important for retrospective assessments of organ doses to be used in occupational radiation epidemiology studies, particularly in the absence of work history or other information regarding the energy of the radiation source. 
 
 Monthly personal dose equivalents and filter ratios under two different metallic filters contained in the Luxel+® dosimeter were collected from Landauer, Inc...
June 19, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29915998/cdaka-a-provably-secure-heterogeneous-cross-domain-authenticated-key-agreement-protocol-with-symptoms-matching-in-tmis
#17
Xiaoxue Liu, Wenping Ma
Telecare Medical Information System (TMIS) provides the flexible and convenient e-health care. It helps the patients to gain health monitoring information and provides patients to share their experience wirelessly. Traditional authentication and key agreement (AKA) protocols in TMIS are mostly considered in same-domain environment. However, future generation network may integrate various of wireless mesh networks under various domain. What's more, patients heterogeneous cross-domain service has become an inevitable trend...
June 18, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29915997/synthetic-biology-advances-and-applications-in-the-biotechnology-industry-a-perspective
#18
Leonard Katz, Yvonne Y Chen, Ramon Gonzalez, Todd C Peterson, Huimin Zhao, Richard H Baltz
Synthetic biology is a logical extension of what has been called recombinant DNA (rDNA) technology or genetic engineering since the 1970s. As rDNA technology has been the driver for the development of a thriving biotechnology industry today, starting with the commercialization of biosynthetic human insulin in the early 1980s, synthetic biology has the potential to take the industry to new heights in the coming years. Synthetic biology advances have been driven by dramatic cost reductions in DNA sequencing and DNA synthesis; by the development of sophisticated tools for genome editing, such as CRISPR/Cas9; and by advances in informatics, computational tools, and infrastructure to facilitate and scale analysis and design...
June 18, 2018: Journal of Industrial Microbiology & Biotechnology
https://www.readbyqxmd.com/read/29915957/transcriptional-analysis-of-immune-genes-in-epstein-barr-virus-associated-gastric-cancer-and-association-with-clinical-outcomes
#19
Raghav Sundar, Aditi Qamra, Angie Lay Keng Tan, Shenli Zhang, Cedric Chuan Young Ng, Bin Tean Teh, Jeeyun Lee, Kyoung-Mee Kim, Patrick Tan
BACKGROUND: Epstein-Barr virus-associated gastric cancer (EBVaGC) has traditionally been associated with high expression of PD-L1 and immune infiltration. Correlations between PD-L1 and other immune-related gene (IRG) expressions in EBVaGC have not been previously described. METHODS: We performed NanoString® transcriptomic profiling and PD-L1 immunohistochemistry (IHC) (using the FDA approved Dako PD-L1 IHC 22C3) on EBVaGC samples from gastric cancer patients undergoing primary tumor resections at Samsung Medical Centre, South Korea...
June 18, 2018: Gastric Cancer
https://www.readbyqxmd.com/read/29914907/beliefs-of-a-traditional-rural-indian-family-towards-naturalistic-and-faith-healing-for-treating-epilepsy-a-case-study
#20
Sudip Bhattacharya, Amarjeet Singh
In this case study, we describe our experiences with a rural poor family from north India that initially contacted faith healers for treatment of their child who was having symptoms suggestive of epilepsy, but the seizures continued even after this. The family migrated to a city, where they started allopathic treatment, but eventually they had to discontinue it as there was no apparent relief. Again, they went back to their native village and restarted the treatment from the faith healer.This case study highlights the fact that in spite of the significant development of medical science, many questions pertaining to epilepsy treatment are still unanswered...
June 17, 2018: BMJ Case Reports
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