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https://www.readbyqxmd.com/read/29668190/bedsharing-at-home-breastfeeding-and-sudden-infant-death-recommendations-for-health-professionals
#1
Alejandro Jenik, Roxana Conti
The Sudden and Unexpected Infant Death Task Force together with the Subcommittee on Breastfeeding of the Sociedad Argentina de Pediatría have issued updated recommendations on bedsharing with the parents, a practice which remains controversial. Sleeping with the mother maximizes breastfeeding, which is protective against Sudden Infant Death. There is a small group of infants that have been associated with an increased risk of Sudden Infant Death and fatal sleeping accidents in certain circumstances. These hazards include parental smoking, sedating drugs or medication and alcohol consumption prior to sleep and sofa sharing situations...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29668072/a-unique-telomere-dna-expansion-phenotype-in-human-retinal-rod-photoreceptors-associated-with-aging-and-disease
#2
W Robert Bell, Alan K Meeker, Anthony Rizzo, Sumit Rajpara, Ian M Rosenthal, Miguel Flores Bellver, Silvia Aparicio Domingo, Xiufeng Zhong, John R Barber, Corinne E Joshu, M Valeria Canto-Soler, Charles G Eberhart, Christopher M Heaphy
We have identified a discrete, focal telomere DNA expansion phenotype in the photoreceptor cell layer of normal, non-neoplastic human retinas. This phenotype is similar to that observed in a subset of human cancers, including a large fraction of tumors of the central nervous system, which maintain their telomeres via the non-telomerase-mediated alternative lengthening of telomeres (ALT) mechanism. We observed that these large, ultra-bright telomere DNA foci are restricted to the rod photoreceptors and are not observed in other cell types...
April 18, 2018: Brain Pathology
https://www.readbyqxmd.com/read/29668033/sexual-dimorphism-in-postnatal-gonadotropin-levels-in-infancy-reflects-diverse-maturation-of-the-ovarian-and-testicular-hormone-synthesis
#3
Tanja Kuiri-Hänninen, Leo Dunkel, Ulla Sankilampi
BACKGROUND: The postnatal gonadotropin surge is sexually dimorphic: FSH levels predominate in girls and LH levels in boys. However, in preterm (PT) girls, both gonadotropin levels are higher than in PT boys. OBJECTIVE: To evaluate how gonadal maturation contributes to the sex differences in FSH and LH. DESIGN: Monthly follow-up of 58 full-term (FT, 29 boys) and 67 PT (33 boys) infants from one week (D7) to six months of age (M1-M6). Analyses were also done according to postmenstrual (PM) age in PT infants...
April 18, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29668026/nicu-graduates-the-role-of-the-allied-health-team-in-follow-up
#4
Jane L Orton, Joy E Olsen, Katherine Ong, Rochelle Lester, Alicia J Spittle
Infants who graduate from the neonatal intensive care unit, including those infants born preterm and/or with brain injury, are at increased risk of long-term neurodevelopmental impairments. The developmental allied health team, consisting of physical therapy, occupational therapy, and speech pathology, is crucial in early evaluation of gross motor, fine motor, feeding, and language development. Surveillance of neurodevelopment in the first year of life is essential to ensure early detection of specific developmental delays and impairments, and to ensure timely referral for early intervention...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668025/general-movements-a-behavioral-biomarker-of-later-motor-and-cognitive-dysfunction-in-nicu-graduates
#5
Colleen Peyton, Christa Einspieler
Infants who have graduated from a neonatal intensive care unit require close follow-up because they have a greater chance of experiencing later motor and cognitive difficulties; however, these difficulties are often challenging to identify at an early age. The General Movement Assessment is a low-cost and highly reliable tool that can indicate abnormal neurological development in young high-risk infants, but it has not yet been widely implemented in the United States. In this review, we discuss the literature about the use of the General Movement Assessment in high-risk infants and how to implement the tool in a clinical setting...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668024/nutrition-considerations-after-nicu-discharge
#6
Taylor Peters, Cecelia Pompeii-Wolfe
Preterm infants are at high nutrition risk during neonatal intensive care and well after discharge. Nutrition care should be individualized and provided by a multidisciplinary team including a dietitian. Breast milk, the gold standard for feeding, may not meet the increased needs of preterm infants and may require fortification or supplementation. Decisions regarding formula choice and calorie concentration can also be challenging and require individualization based on growth, intake, and individual need. Developmental milestones should be considered during the initation of complementary food...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668023/common-queries-about-immunizations-in-preterm-infants
#7
Ansul Asad
Preterm infants are at an increased risk of morbidity and mortality from vaccine-preventable diseases. Despite this, delays in routine immunization of preterm infants are common. Available guidelines clearly state that they should be immunized according to chronological age, irrespective of gestational age and birth weight or current weight. In this article, we try to assuage parental and provider doubts by reviewing data about immunogenicity, safety, and responses to routine immunizations in preterm infants with and without comorbidities...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668022/follow-up-care-for-high-risk-preterm-infants
#8
Stephannie M B Voller
Preterm infants continue to have complex medical and developmental issues after discharge from the neonatal intensive care unit. Over the past few decades there has been an increase in preterm births and a decrease in preterm mortality. Many infants are referred to follow-up clinics that specialize in neurodevelopmental assessment. Often, a community pediatrician or family practitioner provides both the medical management and observes developmental milestones of the high-risk neonate. Intense medical management, early identification of delay, and referral for developmental services may improve preterm infant outcomes...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29667866/assessment-and-comparison-of-phcs-removal-from-three-types-of-soils-sand-silt-loam-and-clay-using-supercritical-fluid-extraction
#9
Mahmoud Meskar, Majid Sartaj, Julio Angel Infante Sedano
Supercritical fluid extraction (SFE) was applied to investigate the removal of petroleum hydrocarbons (PHCs) from contaminated soils. Per an initial set of tests for different extraction modes and time durations, the combination of 10 min static mode followed by 10 min dynamic mode, repeated for 3 cycles for a total time of 60 min resulted in the highest PHCs removal percentages. SFE experiments were performed at 33 MPa pressure and 75 °C temperature to investigate the influence of soil texture and grain size...
April 18, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29667726/interventions-for-infantile-haemangiomas-of-the-skin
#10
REVIEW
Monica Novoa, Eulalia Baselga, Sandra Beltran, Lucia Giraldo, Ali Shahbaz, Hector Pardo-Hernandez, Ingrid Arevalo-Rodriguez
BACKGROUND: Infantile haemangiomas (previously known as strawberry birthmarks) are soft, raised swellings of the skin that occur in 3% to 10% of infants. These benign vascular tumours are usually uncomplicated and tend to regress spontaneously. However, when haemangiomas occur in high-risk areas, such as near the eyes, throat, or nose, impairing their function, or when complications develop, intervention may be necessary. This is an update of a Cochrane Review first published in 2011...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29667697/resources-for-psychiatric-clinicians-working-with-breastfeeding-mothers
#11
Nancy M Terres
In today's health care-focused climate, in which encouraging breastfeeding is part of national and international health care initiatives, clinicians in any field should have resources available for breastfeeding mothers. The current article provides information for psychiatric clinicians on how breastfeeding may affect women with psychiatric conditions, the type of lactation counselor likely to be best prepared to collaborate with psychiatric clinicians, and resources available regarding maternal psychiatric medications safe for breastfeeding infants...
April 17, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29667517/salt-intake-of-lactating-women-as-assessed-by-modified-food-weighted-records
#12
Lijun Duan, Wendi Liu, Peng Zhang, Shiyan Liu, Xiaotong Liu, Maocheng Sang, Lu Liu, Haiyue Lin, Zhongna Sang
OBJECTIVE: High salt intake among lactating women can increase the risk of hypertension and cardiovascular disease in infants/offspring. However, considering the limited salt intake data in lactating women, the aims of this study were to compare the salt intake assessed by modified food weighted records (FWR) with that estimated by 24-h urinary sodium excretion and to investigate the salt intake of lactating women. METHODS: In total, 30 lactating women aged 20-39 years who were 2 to 4 months postpartum were recruited from the cities of Tianjin and Luoyang in China...
April 18, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29667359/predicting-responses-to-mechanical-ventilation-for-preterm-infants-with-acute-respiratory-illness-using-artificial-neural-networks
#13
Katharine Brigham, Samir Gupta, John C Brigham
Infants born prematurely are particularly susceptible to respiratory illness due to underdeveloped lungs, which can often result in fatality. Preterm infants in acute stages of respiratory illness typically require mechanical ventilation assistance, and the efficacy of the type of mechanical ventilation and its delivery has been the subject of a number clinical studies. With recent advances in machine learning approaches, particularly deep learning, it may be possible to estimate future responses to mechanical ventilation in real-time, based on ventilation monitoring up to the point of analysis...
April 17, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29667336/optimal-breastfeeding-durations-for-hiv-exposed-infants-the-impact-of-maternal-art-use-infant-mortality-and-replacement-feeding-risk
#14
Divya Mallampati, Rachel L MacLean, Roger Shapiro, Francois Dabis, Barbara Engelsmann, Kenneth A Freedberg, Valeriane Leroy, Shahin Lockman, Rochelle Walensky, Nigel Rollins, Andrea Ciaranello
INTRODUCTION: In 2010, the WHO recommended women living with HIV breastfeed for 12 months while taking antiretroviral therapy (ART) to balance breastfeeding benefits against HIV transmission risks. To inform the 2016 WHO guidelines, we updated prior research on the impact of breastfeeding duration on HIV-free infant survival (HFS) by incorporating maternal ART duration, infant/child mortality and mother-to-child transmission data. METHODS: Using the Cost-Effectiveness of Preventing AIDS Complications (CEPAC)-Infant model, we simulated the impact of breastfeeding duration on 24-month HFS among HIV-exposed, uninfected infants...
April 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29667311/how-japanese-nurses-participate-in-decision-making-infants-with-congenital-life-threatening-conditions
#15
Sohei Shitaya, Nobue Nakamura, Naho Sato
BACKGROUND: In Japan, owing to the progress in medical technology, more children with congenital life-threatening conditions survive than ever before. Nurses who care for these children may also influence decision making in difficult situations. AIM: We aimed to describe Japanese nurses' approach toward medical decision making when caring for families of infants with congenital life-threatening conditions. Frequently, these nurses must care for and support parents with ambivalent feelings...
April 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29667253/patient-blood-management-what-does-this-actually-mean-for-neonates-and-infants
#16
REVIEW
G L Crighton, H V New, H G Liley, S J Stanworth
Patient blood management (PBM) refers to an evidence-based package of care that aims to improve patient outcomes by optimal use of transfusion therapy, including managing anaemia, preventing blood loss and improving anaemia tolerance in surgical and other patients who may need transfusion. In adults, PBM programmes are well established, yet the definition and implementation of PBM in neonates and children lags behind. Neonates and infants are frequently transfused, yet they are often under-represented in transfusion trials...
April 17, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29667223/mental-health-and-well-being-in-parents-of-excessively-crying-infants-prospective-evaluation-of-a-support-package
#17
C Powell, D Bamber, J Long, R Garratt, J Brown, S Rudge, T Morris, N Bhupendra Jaicim, R Plachcinski, S Dyson, E M Boyle, I St James-Roberts
BACKGROUND: During the first 4 months of age, approximately 20% of infants cry a lot without an apparent reason. Most research has targeted the crying, but the impact of the crying on parents, and subsequent outcomes, need to receive equal attention. This study reports the findings from a prospective evaluation of a package of materials designed to support the well-being and mental health of parents who judge their infant to be crying excessively. The resulting "Surviving Crying" package comprised a website, printed materials, and programme of Cognitive Behaviour Therapy-based support sessions delivered to parents by a qualified practitioner...
April 17, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29666787/cardiac-output-monitoring-in-preterm-infants
#18
REVIEW
Matthew McGovern, Jan Miletin
Maintaining optimal circulatory status is a key component of preterm neonatal care. Low-cardiac output (CO) in the preterm neonate leads to inadequate perfusion of vital organs and has been linked to a variety of adverse outcomes with heightened acute morbidity and mortality and adverse neurodevelopmental outcomes. Having technology available to monitor CO allows us to detect low-output states and potentially intervene to mitigate the unwanted effects of reduced organ perfusion. There are many technologies available for the monitoring of CO in the preterm neonatal population and while many act as useful adjuncts to aid clinical decision-making no technique is perfect...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29666710/acute-chest-syndrome-progressing-to-ards-in-a-patient-of-25-week-gestation
#19
Jefferson Chambers, Nichole Smith, Matthew Sehring, Subramanyam Chittivelu
Acute chest syndrome is a complication of sickle cell disease and represents the highest cause of mortality in those afflicted with the disorder. Pregnancy represents an increased risk for complications of sickle cell disease in both the mother and fetus. We present a case of a 20-year-old patient with known sickle cell disease who was at 25-week gestation and developed acute chest syndrome refractory to conventional therapies and requiring emergency cesarean section. Following delivery, the patient developed acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO)...
2018: Case Reports in Critical Care
https://www.readbyqxmd.com/read/29666562/preclinical-in-vitro-and-in-vivo-evaluation-of-18-f-fe-suppy-for-cancer-pet-imaging-limitations-of-a-xenograft-model-for-colorectal-cancer
#20
T Balber, J Singer, N Berroterán-Infante, M Dumanic, L Fetty, J Fazekas-Singer, C Vraka, L Nics, M Bergmann, K Pallitsch, H Spreitzer, W Wadsak, M Hacker, E Jensen-Jarolim, H Viernstein, M Mitterhauser
Molecular imaging probes such as PET-tracers have the potential to improve the accuracy of tumor characterization by directly visualizing the biochemical situation. Thus, molecular changes can be detected early before morphological manifestation. The A3 adenosine receptor (A3 AR) is described to be highly expressed in colon cancer cell lines and human colorectal cancer (CRC), suggesting this receptor as a tumor marker. The aim of this preclinical study was the evaluation of [18 F]FE@SUPPY as a PET-tracer for CRC using in vitro imaging and in vivo PET imaging...
2018: Contrast Media & Molecular Imaging
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