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https://www.readbyqxmd.com/read/27905673/single-versus-multiple-visits-for-endodontic-treatment-of-permanent-teeth
#1
REVIEW
Maddalena Manfredi, Lara Figini, Massimo Gagliani, Giovanni Lodi
BACKGROUND: Root canal treatment (RoCT), or endodontic treatment, is a common procedure in dentistry. The main indications for RoCT are irreversible pulpitis and necrosis of the dental pulp caused by carious processes, tooth cracks or chips, or dental trauma. Successful RoCT is characterised by an absence of symptoms (i.e. pain) and clinical signs (i.e. swelling and sinus tract) in teeth without radiographic evidence of periodontal involvement (i.e. normal periodontal ligament). The success of RoCT depends on a number of variables related to the preoperative condition of the tooth, as well as the endodontic procedures...
December 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27898727/biological-markers-for-pulpal-inflammation-a-systematic-review
#2
Dan-Krister Rechenberg, Johnah C Galicia, Ove A Peters
BACKGROUND AND OBJECTIVE: Pulpitis is mainly caused by an opportunistic infection of the pulp space with commensal oral microorganisms. Depending on the state of inflammation, different treatment regimes are currently advocated. Predictable vital pulp therapy depends on accurate determination of the pulpal status that will allow repair to occur. The role of several players of the host response in pulpitis is well documented: cytokines, proteases, inflammatory mediators, growth factors, antimicrobial peptides and others contribute to pulpal defense mechanisms; these factors may serve as biomarkers that indicate the status of the pulp...
2016: PloS One
https://www.readbyqxmd.com/read/27891455/unmasking-the-effect-of-analgesics-on-endodontic-diagnosis-using-a-novel-bite-force-sensor-device-a-prospective-randomized-clinical-trial
#3
Sushil Kishnani, Suparna Ganguly Saha, Anuj Bhardwaj, Sandeep Dubey, Mainak Saha, Shubham Kala, Sohini Jain, Shweta Narwani
INTRODUCTION: A definitive diagnosis is of primary importance before initiating any endodontic treatment; yet, there are occasions when the dental professional is unable to accurately reproduce the patient's chief complaint, as it can pose a dilemma and may require consideration of multiple variables in order to reach an accurate diagnosis. So to overcome this problem, a methodical approach in providing endodontic treatment should be implemented which includes diagnosis, definitive dental treatment and adjunctive drug therapy, known as the "3D" strategy...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27837343/effect-of-preoperative-oral-analgesics-on-pulpal-anesthesia-in-patients-with-irreversible-pulpitis-a-systematic-review-and-meta-analysis
#4
REVIEW
Armin Shirvani, Sayna Shamszadeh, Mohammad Jafar Eghbal, Laleh Alim Marvasti, Saeed Asgary
OBJECTIVES: The objectives of this study were to assess the efficacy of preemptive oral administration of single dose of non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen on the local anesthetic success in adults with irreversible pulpitis and to find the possible covariates that could predict treatment effect. MATERIALS AND METHODS: A systematic search using electronic databases up to March 2015 was conducted. Odds ratio (OR) and 95% confidence intervals (CIs) were estimated using random and fixed-effect inverse variance method...
November 11, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27834417/inferior-alveolar-nerve-block-for-the-treatment-of-teeth-presenting-with-irreversible-pulpitis-a-systematic-review-of-the-literature-and-meta-analysis
#5
Stefano Corbella, Silvio Taschieri, Francesco Mannocci, Eyal Rosen, Igor Tsesis, Massimo Del Fabbro
OBJECTIVE: The objective of the present systematic review was to evaluate, in patients with irreversible pulpitis affecting mandibular posterior teeth, if premedication with nonsteroidal anti-inflammatory drugs can increase the efficacy of inferior alveolar nerve block (IANB) if compared to placebo administration; if one anesthetic agent is more effective than another; if 1.8 mL injection is more effective than 3.6 mL injection to increase the efficacy of IANB; and if supplementary buccal injection is able to increase the efficacy of IANB as compared to a negative control/placebo group...
November 10, 2016: Quintessence International
https://www.readbyqxmd.com/read/27829761/evaluation-of-oral-and-periodontal-status-of-leprosy-patients-in-dindigul-district
#6
S A Jacob Raja, J Johnson Raja, R Vijayashree, B Meena Priya, G Sai Anusuya, P Ravishankar
AIM: After the introduction of the multidrug therapy, the incidence of leprosy is decreasing every year. However, periodontal complaints are commonly seen in these patients due to compromised immunity and impaired oral hygiene. The aim of the present study is to assess the oral and periodontal status of the leprosy patients in Dindigul district. MATERIALS AND METHODS: The study was conducted on 62 patients treated in a leprosy center at Dindigul district. Among these, 22 (35...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27824975/analysis-of-endodontic-complications-following-fixed-prosthodontic-rehabilitation
#7
Zeynep Uzgur, Recep Uzgur, Hakan Çolak, Ertuğrul Ercan, Mehmet Dallı
PURPOSE: The aim of this study was to determine endodontic treatment needs and types of endodontic disease following fixed prosthodontic treatment 24 hours after tooth preparation, 1 week after tooth preparation, 1 month after placement, and 6 months after placement. MATERIALS AND METHODS: Study groups consisted of patients who attended a university dental hospital department of prosthodontics for fixed prosthodontic treatment from January 2011 to December 2013...
November 2016: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/27815076/sirt6-protects-against-lipopolysaccharide-lps-induced-apoptosis-in-human-dental-pulp-cells-by-deacetylation-of-ku70
#8
Wanhong Chen, Xun Chen, Yuhuan Sun
Progression of pulpitis is facilitated by the immune system's response to bacteria, enhancing the production of inflammatory regulators. Bacterial lipopolysaccharide (LPS) is the major structural component of the outer wall of all Gram-negative bacteria and a potent activator of the immune system. Apoptosis is believed to play an important role in the inflammatory process of pulpitis. SIRT6 is a member of class III of histone deacetylases (HDACs), also called sirtuins (SIRTs). The role of SIRT6 in apoptosis in pulpitis is unknown...
November 1, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27803922/clinical-and-histological-evaluation-of-direct-pulp-capping-on-human-pulp-tissue-using-a-dentin-adhesive-system
#9
Alicja Nowicka, Ryta Łagocka, Mariusz Lipski, Mirosław Parafiniuk, Katarzyna Grocholewicz, Ewa Sobolewska, Agnieszka Witek, Jadwiga Buczkowska-Radlińska
Objective. This study presents a clinical and histological evaluation of human pulp tissue responses after direct capping using a new dentin adhesive system. Methods. Twenty-eight caries-free third molar teeth scheduled for extraction were evaluated. The pulps of 22 teeth were mechanically exposed and randomly assigned to 1 of 2 groups: Single Bond Universal or calcium hydroxide. Another group of 6 teeth acted as the intact control group. The periapical response was assayed, and a clinical examination was performed...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27790270/vital-pulp-therapy-of-a-symptomatic-immature-permanent-molar-with-long-term-success
#10
Sedigheh Sabbagh, Alireza Sarraf Shirazi, Mohammad Jafar Eghbal
Vital pulp therapy (VPT) is the preferred conservative treatment for preservation of symptomatic pulps in immature permanent teeth. The present case report summarizes VPT of an immature permanent molar with irreversible pulpitis associated with apical periodontitis in a 9-year-old boy. Cervical pulpotomy was performed and radicular pulp stumps were covered with calcium-enriched mixture (CEM) cement; the tooth was then restored with stainless steel crown. After a 50-month follow-up period, the pulpotomized molar was clinically functional and asymptomatic...
2016: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/27790255/comparison-of-manual-and-rotary-instrumentation-on-postoperative-pain-in-teeth-with-asymptomatic-irreversible-pulpitis-a-randomized-clinical-trial
#11
Bita Talebzadeh, Saeed Nezafati, Saeed Rahimi, Shahriar Shahi, Mehrdad Lotfi, Negin Ghasemi
INTRODUCTION: One of the most common complications of root canal treatment is postoperative pain. The aim of the present clinical trial was to compare the severity of postoperative pain after root canal preparation with RaCe rotary system and hand K-Flexofile. METHODS AND MATERIALS: A total of 96 mandibular first and second molars were divided into two groups (n=48) based on root canal preparation technique. The teeth in both groups underwent one-session root canal treatment and the severity of postoperative pain was evaluated using visual analog scale (VAS) at 4-, 8-, 12-, 24- and 48-h and 1-week intervals...
2016: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/27790253/effect-of-dexamethasone-intraligamentary-injection-on-post-endodontic-pain-in-patients-with-symptomatic-irreversible-pulpitis-a-randomized-controlled-clinical-trial
#12
Payman Mehrvarzfar, Ehsan Esnashari, Reyhaneh Salmanzadeh, Mahta Fazlyab, Mahyar Fazlyab
INTRODUCTION: The aim of this randomized-controlled clinical trial was to assess the effect of intraligamentary (PDL) injection of dexamethasone on onset and severity of post-treatment pain in patients with symptomatic irreversible pulpitis. METHODS AND MATERIALS: A total number of 60 volunteers were included according to the inclusion criteria and were assigned to three groups (n=20). After administration of local anesthesia and before treatment, group 1 (control) PDL injection was done with syringe containing empty cartridge, while in groups 2 and 3 the PDL injection was done with 0...
2016: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/27771163/influence-of-secondary-wound-healing-after-mandibular-third-molar-coronectomy
#13
S Franco, E Vignudelli, G Monaco, C Marchetti
Our aim was to describe the postoperative morbidity related to secondary wound healing after coronectomy. Ten of 116 patients treated by coronectomy healed by second intention as a result of failed sutures. We made a retrospective analysis after two years to evaluate the postoperative morbidity related to secondary wound healing. The complete closure of the alveolus of the 10 surgical sites was recorded three months after coronectomy. No patients had postoperative infections, dry socket, or pulpitis. All patients were free of symptoms, the retained roots were completely included, and were not detectable with a periodontal probe...
October 19, 2016: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27769675/pain-reduction-in-untreated-symptomatic-irreversible-pulpitis-using-liposomal-bupivacaine-exparel-a-prospective-randomized-double-blind-trial
#14
Kristy Bultema, Sara Fowler, Melissa Drum, Al Reader, John Nusstein, Mike Beck
INTRODUCTION: In the treatment of patients with symptomatic irreversible pulpitis, endodontic debridement is a predictable method to relieve pain. However, there are clinical situations in which emergency care cannot be provided immediately. An unexplored treatment option in these cases may be the use of a long-acting anesthetic to reduce pain in untreated irreversible pulpitis. Some medical studies have shown potential for infiltrations of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, San Diego, CA) to prolong pain relief and reduce opioid use postoperatively...
October 18, 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/27767119/antibiotics-are-not-useful-to-reduce-pain-associated-with-irreversible-pulpitis
#15
Eileen Hoskin, Analia Veitz-Keenan
Data sourcesCochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, Clinical Trials.gov and the WHO International Clinical Trials Registry Platform. There were no language restrictions.Study selectionRandomised controlled trials which compared the relief of pain with systemic antibiotics and analgesics against placebo and analgesics in the preoperative phase of irreversible pulpitis. The primary interest was pain control with an antibiotic or without one in the presence of analgesics...
September 2016: Evidence-based Dentistry
https://www.readbyqxmd.com/read/27757378/factors-affecting-dental-diseases-presenting-at-the-university-of-ghana-hospital
#16
Joseph Nimako-Boateng, Michael Owusu-Antwi, Priscilla Nortey
Dental diseases are common in man and range from a toothache to cancers of the head and neck. Dental conditions can affect our capacity to function effectively in areas such as smiling, chewing and speaking. The objective of this study was to describe the main types of dental conditions presenting at the University Hospital between January 2006 and December 2011 and to determine factors associated with the top five diagnosed conditions as well as the acute and chronic conditions. A retrospective review of all 5012 clinical records of dental patients visiting the dental unit within the period stated was carried out...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27752174/-impact-of-different-degree-pulpitis-on-cell-proliferation-and-osteoblastic-differentiation-of-dental-pulp-stem-cell-in-beagle-immature-premolars
#17
L Ling, Y M Zhao, L H Ge
OBJECTIVE: To compare the proliferation and osteoblastic differentiation of dental pulp stem cell (DPSC) isolated from normal and inflamed pulps of different degrees in Beagle immature premolars, and provide evidence for the use of inflammatory DPSC (IDPSC). METHODS: This study evaluated 14 Beagle's young premolars (21 roots). In the experiment group, irreversible pulpitis was induced by pulp exposure and the inflamed pulps were extracted 2 weeks and 6 weeks after the pulp chamber opening...
October 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27747243/functional-roles-of-nod1-in-odontoblasts-on-dental-pulp-innate-immunity
#18
Yuki Hosokawa, Kouji Hirao, Hiromichi Yumoto, Ayako Washio, Tadashi Nakanishi, Daisuke Takegawa, Chiaki Kitamura, Takashi Matsuo
Caries-related pathogens are first recognized by odontoblasts and induce inflammatory events that develop to pulpitis. Generally, initial sensing of microbial pathogens is mediated by pattern recognition receptors, such as Toll-like receptor and nucleotide-binding oligomerization domain (NOD); however, little is known about NODs in odontoblasts. In this study, the levels of NODs expressed in rat odontoblastic cell line, KN-3, were assessed by flow cytometry and the levels of chemokines in NOD-specific ligand-stimulated KN-3 cells were analyzed by real-time PCR and ELISA...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27744048/pulp-and-apical-tissue-response-to-deep-caries-in-immature-teeth-a-histologic-and-histobacteriologic-study
#19
Domenico Ricucci, José F Siqueira, Simona Loghin, Louis M Lin
: Descriptions of the pathologic changes in the pulp and associated apical structures of human immature teeth in response to deep caries are lacking in the literature. OBJECTIVES: This article describes the histologic events associated with the radicular pulp and the apical tissues of human immature teeth following pulp inflammation and necrosis. METHODS: Twelve immature teeth with destructive caries lesions were obtained from 8 patients. Two intact immature teeth served as controls...
October 12, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27743595/relevance-of-the-plasminogen-system-in-physiology-pathology-and-regeneration-of-oral-tissues-from-the-perspective-of-dental-specialties
#20
Christian Wehner, Klara Janjić, Hermann Agis
Plasmin is a proteolytic enzyme that is crucial in fibrinolysis. In oral tissues, the plasminogen system plays an essential role in physiological and pathological processes, which in addition to fibrinolysis include degradation of extracellular matrix, inflammation, immune response, angiogenesis, tissue remodeling, cell migration, and wound healing. Oral tissues reveal a change in the plasminogen system during pathological processes such as periodontitis, peri-implantitis, or pulpitis, as well as in response to mechanical load...
October 5, 2016: Archives of Oral Biology
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