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https://www.readbyqxmd.com/read/28320541/comparative-evaluation-of-premedication-with-ketorolac-and-prednisolone-on-postendodontic-pain-a-double-blind-randomized-controlled-trial
#1
R Praveen, Sophia Thakur, M Kirthiga
INTRODUCTION: The present clinical trial aimed to evaluate and compare the effect of a single pretreatment dose of ketorolac (20 mg), prednisolone (30 mg), and placebo on postendodontic pain in patients undergoing endodontic therapy for irreversible pulpitis or pulpal necrosis using a visual analog scale. METHODS: Ninety-two subjects were included in the present trial; 46 subjects had a pulpal diagnosis of irreversible pulpitis, and the other 46 had pulpal necrosis...
March 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28320537/a-randomized-clinical-trial-comparing-2-ibuprofen-formulations-in-patients-with-acute-odontogenic-pain
#2
Tanjit Taggar, Di Wu, Asma A Khan
INTRODUCTION: Ibuprofen sodium dihydrate, a new formulation of ibuprofen, was introduced with the claim of faster onset of analgesia. Most of the data on this new ibuprofen formulation are drawn from studies using the oral surgery model. Because this model differs significantly from the endodontic pain model, we conducted a study comparing ibuprofen sodium dihydrate with conventional ibuprofen acid in endodontic pain patients. METHODS: This randomized, double-masked study recruited subjects experiencing moderate to severe pain from a tooth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis (n = 41)...
March 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28294357/expression-of-factors-involved-in-dental-pulp-physiopathological-processes-by-nemotic-human-pulpal-fibroblasts
#3
J Le Clerc, S Tricot-Doleux, P Pellen-Mussi, M Pérard, S Jeanne, F Pérez
AIM: To investigate in human pulp fibroblasts (HDPF) the expression of factors involved in dental pulp physiopathological processes and in an experimental model of cell activation called nemosis, and to compare the behaviour of pulp cell activation with sound lung fibroblasts MRC5, employed as a reference model for nemosis. METHODOLOGY: Nemotic response was induced in 3-dimensional cultures of HDPF and lung fibroblasts. The expressions of molecules involved in physiological (alkaline phosphatase, type I collagen) and in inflammatory processes (IL-6, CXCL8, CCL20, COX-2) were studied using real-time PCR...
March 10, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28293399/up-regulation-of-tlr2-and-tlr4-in-high-mobility-group-box1-stimulated-macrophages-in-pulpitis-patients
#4
Javad Mahmoudi, Babak Sabermarouf, Behzad Baradaran, Leila Sadat-Hatamnezhad, Siamak Sandoghchian Shotorbani
OBJECTIVES: High Mobility Group Box1 (HMGB1) is a nonhistone, DNA-binding protein that serves a crucial role in regulating gene transcription and is involved in a variety of proinflammatory, extracellular activities. The aim of this study was to explore whether HMGB1 stimulation can up-regulate the expression of Toll-like Receptor 2 (TLR2) and Toll-like Receptor 4 (TLR4) on macrophages from pulpitis and to clarify the subsequent events involving Th17 cells and Th17 cell-associated cytokine changes...
February 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28292597/the-effect-of-the-dental-operating-microscope-on-the-outcome-of-nonsurgical-root-canal-treatment-a-retrospective-case-control-study
#5
Navid Khalighinejad, Anita Aminoshariae, James C Kulild, Kristin A Williams, Jeannie Wang, Andre Mickel
INTRODUCTION: The aim of the current investigation was to assess the effect of the use of a dental operating microscope on the outcome of nonsurgical root canal treatment (NS RCT) while treating the mesiobuccal (MB) root of the maxillary first molar. METHODS: This retrospective investigation included endodontically treated maxillary first molars (ETMs) with apparent adequate previous NS RCT and restorations referred for endodontic retreatment at the endodontic graduate clinic...
March 11, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28279187/pulp-regeneration-by-transplantation-of-dental-pulp-stem-cells-in-pulpitis-a-pilot-clinical-study
#6
Misako Nakashima, Koichiro Iohara, Masashi Murakami, Hiroshi Nakamura, Yayoi Sato, Yoshiko Ariji, Kenji Matsushita
BACKGROUND: Experiments have previously demonstrated the therapeutic potential of mobilized dental pulp stem cells (MDPSCs) for complete pulp regeneration. The aim of the present pilot clinical study is to assess the safety, potential efficacy, and feasibility of autologous transplantation of MDPSCs in pulpectomized teeth. METHODS: Five patients with irreversible pulpitis were enrolled and monitored for up to 24 weeks following MDPSC transplantation. The MDPSCs were isolated from discarded teeth and expanded based on good manufacturing practice (GMP)...
March 9, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28259322/combination-analgesics-reduce-postoperative-pain-in-teeth-with-a-pulpal-diagnosis-of-irreversible-pulpitis
#7
Sami Chogle, Obadah Attar
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. Elzaki WM, Abubakr NH, Ziada HM, Ibrahim YE. J Endod 2016;42(6):835-42. SOURCE OF FUNDING: No source of funding was identified. The study was conducted by the faculty of the Dentistry Department, University of Khartoum and the Khartoum Teaching Hospital emergency clinic TYPE OF STUDY/DESIGN: Double-blind randomized controlled trial...
March 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28215443/2-mepivacaine-seems-to-do-better-than-2-%C3%A2-lidocaine-in-achieving-successful-anesthesia-in-posterior-teeth-with-irreversible-pulpitis
#8
Romina Brignardello-Petersen
No abstract text is available yet for this article.
February 16, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28214370/the-effect-of-preoperative-submucosal-administration-of-tramadol-on-the-success-rate-of-inferior-alveolar-nerve-block-on-mandibular-molars-with-symptomatic-irreversible-pulpitis-a-randomized-double-blind-placebo-controlled-clinical-trial
#9
A De Pedro-Muñoz, J Mena-Álvarez
AIM: This randomized, double-blind, placebo-controlled, clinical trial was designed to improve the success of inferior alveolar nerve blocks (IANB) in mandibular molars with symptomatic irreversible pulpitis (SIP) by means of preoperative submucosal administration of 50 mg tramadol. METHODOLOGY: Forty-two patients with a mandibular molar diagnosed with SIP took part in the trial. Patients were assigned randomly to one of two groups: tramadol group (n = 21), who received 50 mg tramadol in 1 mL by mandibular infiltration, and a placebo group (n = 21), who received 1 mL of normal saline administered to the affected tooth by the same means...
February 18, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28194366/maxillary-first-molar-with-7-root-canals-diagnosed-using-cone-beam-computed-tomography
#10
Evaldo Rodrigues, Antônio Henrique Braitt, Bruno Ferraz Galvão, Emmanuel João Nogueira Leal da Silva
Root canal anatomy is complex, and the recognition of anatomic variations could be a challenge for clinicians. This case report describes the importance of cone beam computed tomographyic (CBCT) imaging during endodontic treatment. A 23 year old woman was referred by her general dental practitioner with the chief complaint of spontaneous pain in her right posterior maxilla. From the clinical and radiographic findings, a diagnosis of symptomatic irreversible pulpitis was made and endodontic treatment was suggested to the patient...
February 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28190451/successful-pulpal-anesthesia-for-symptomatic-irreversible-pulpitis
#11
Melissa Drum, Al Reader, John Nusstein, Sara Fowler
BACKGROUND AND OVERVIEW: Profound pulpal anesthesia after a successful inferior alveolar nerve block can be difficult to achieve when the clinical condition is a pulpal diagnosis of symptomatic irreversible pulpitis. The authors reviewed the literature as it relates to the anesthesia necessary for endodontic therapy of patients with painful, vital, mandibular teeth diagnosed with symptomatic irreversible pulpitis. CONCLUSIONS: Supplemental anesthetic techniques and medications are available that can be used to improve pulpal anesthesia for patients with the clinical condition of symptomatic irreversible pulpitis...
February 9, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28182118/musical-auditory-stimulation-influences-heart-rate-autonomic-responses-to-endodontic-treatment
#12
Milana Drumond Ramos Santana, Eli Carlos Martiniano, Larissa Raylane Lucas Monteiro, Vitor E Valenti, David M Garner, Isabel Cristina Esposito Sorpreso, Luiz Carlos de Abreu
We aimed to evaluate the acute effect of musical auditory stimulation on heart rate autonomic regulation during endodontic treatment. The study included 50 subjects from either gender between 18 and 40 years old, diagnosed with irreversible pulpitis or pulp necrosis of the upper front teeth and endodontic treatment indication. HRV was recorded 10 minutes before (T1), during (T2), and immediately (T3 and T4) after endodontic treatment. The volunteers were randomly divided into two equal groups: exposed to music (during T2, T3, and T4) or not...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28179936/vital-pulp-therapy-with-calcium-silicate-cements-report-of-two-cases
#13
Hengameh Ashraf, Afsaneh Rahmati, Neda Amini
This article describes successful use of calcium-enriched mixture (CEM) cement and Biodentine in apexogenesis treatment in two 8-year-old patients, one with immature permanent molar diagnosed primarily with irreversible pulpitis and the other with partially vital maxillary central incisor. After access cavity preparation, partial pulpotomy in molar and full pulpotomy in central was performed, and the remaining pulps was capped with either Biodentine or CEM cement, in each tooth. The crowns were restored with composite filling material at the following visit...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28179933/role-of-cd146-enrichment-in-purification-of-stem-cells-derived-from-dental-pulp-polyp
#14
Maryam Sadat Tavangar, Seyed-Mojtaba Hosseini, Ali Dehghani-Nazhvani, Ahmad Monabati
INTRODUCTION: Hyperplastic pulpitis (pulp polyp) tissues contains cells with stem cell properties similar to that of the dental pulp stem cells (DPSCs). It has also been shown that CD146 enrichment can homogenize the cultures of DPSCs and enhance the colony forming potentials of their cultures. This study determines whether CD146 enrichment can help purifying the stem cells from heterogeneous cultures of the pulp polyp derived stem cells (PPSCs). METHODS AND MATERIALS: Healthy dental pulps and pulp polyp tissues were enzymatically digested and the harvested single cells were sorted according to the presence of CD146 marker...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28179918/correlation-between-histological-status-of-the-pulp-and-its-response-to-sensibility-tests
#15
Mandana Naseri, Akbar Khayat, Sara Zamaheni, Shiva Shojaeian
INTRODUCTION: The purpose of this study was to assess the accuracy of sensibility tests by correlating it with histologic pulp condition. METHODS AND MATERIALS: Assessment of clinical signs and symptoms were performed on 65 permanent teeth that were scheduled to be extracted for periodontal, prosthodontic or orthodontic reasons. The normal pulp and reversible pulpitis were considered as treatable tooth conditions while irreversible pulpitis and necrosis were considered as untreatable conditions...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28179917/comparison-of-postoperative-pain-after-root-canal-preparation-with-two-reciprocating-and-rotary-single-file-systems-a-randomized-clinical-trial
#16
Narges Farhad Mollashahi, Eshagh Ali Saberi, Seyed Rohollah Havaei, Mohammad Sabeti
INTRODUCTION: Root canal preparation techniques may cause postoperative pain. The aim of the present study was to compare the intensity of postoperative pain after endodontic treatment using hand files, single file rotary (OneShape), and single file reciprocating (Reciproc) systems. METHODS AND MATERIALS: In this single-blind, parallel-grouped randomized clinical trial a total of 150 healthy patients aged between 20 to 50 years old were diagnosed with symptomatic irreversible pulpitis of one maxillary or mandibular molars...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28168240/cracked-tooth-syndrome-mimicking-trigeminal-autonomic-cephalalgia-a-report-of-four-cases
#17
Noboru Noma, Kohei Shimizu, Kosuke Watanabe, Andrew Young, Yoshiki Imamura, Junad Khan
BACKGROUND: This report describes four cases of cracked tooth syndrome secondary to traumatic occlusion that mimicked trigeminal autonomic cephalalgias. All patients were referred by general practitioners to the Orofacial Pain Clinic at Nihon University Dental School for assessment of atypical facial pain. CLINICAL PRESENTATION: Case 1: A 51-year-old woman presented with severe pain in the maxillary and mandibular left molars. Case 2: A 47-year-old woman presented with sharp, shooting pain in the maxillary left molars, which radiated to the temple and periorbital region...
February 6, 2017: Quintessence International
https://www.readbyqxmd.com/read/28134983/effect-of-two-different-concentrations-of-sodium-hypochlorite-on-postoperative-pain-following-single-visit-root-canal-treatment-a-triple-blind-randomized-clinical-trial
#18
S Farzaneh, M Parirokh, N Nakhaee, P V Abbott
AIM: To compare the effects of two different concentrations of NaOCl solution on postoperative pain following single-visit root canal treatment in mandibular molars with irreversible pulpitis. METHODOLOGY: A total of 122 patients who had mandibular molars with irreversible pulpitis were treated. The patients were randomly divided into two groups according to the concentration of NaOCl used during root canal instrumentation - either 2.5% or 5.25%. RaCe rotary instruments were used for root canal preparation and all root canals were filled in one visit...
January 30, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28118417/pain-from-dental-implant-placement-inflammatory-pulpitis-pain-and-neuropathic-pain-present-different-somatosensory-profiles
#19
André Luís Porporatti, Leonardo Rigoldi Bonjardim, Juliana Stuginski-Barbosa, Estevam Augusto Bonfante, Yuri Martins Costa, Paulo César Rodrigues Conti
AIMS: To address the two following questions: (1) What kind of somatosensory abnormalities may be characterized in patients receiving dental implants (IMP), in ongoing inflammatory dental pulpitis (IP) patients, and in neuropathic pain (atypical odontalgia [AO]) patients? and (2) What sort of sensory and neural changes may result from dental implant placement surgery and pulpectomy? METHODS: A total of 60 subjects were divided into three groups: the IMP (n = 20), IP (n = 20), and AO groups (n = 20)...
January 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28072988/-retrospective-analysis-of-pulp-revascularization-in-immature-permanent-teeth-with-diffuse-pulpitis
#20
C F Peng, Y M Zhao, Y Yang, H Liu, M Qin
Objective: To evaluate the treatment effectiveness of revascularization in immature permanent teeth with diffuse pulpitis and to provide an alternative approach for the treatment of these teeth. Methods: Clinical and radiographic data were collected from 17 immature permanent teeth which were diagnosed as diffuse pulpitis and with their pulp extirpated at Emergency Department of Peking University School and Hospital of Stomatology. All these teeth were treated using pulp revascularization at Department of Pediatric Dentistry...
January 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
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