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https://www.readbyqxmd.com/read/28600966/inflammatory-cytokines-in-normal-and-irreversibly-inflamed-pulps-a-systematic-review
#1
REVIEW
Vivian Hirsch, Michael Wolgin, Aleksandr V Mitronin, Andrej M Kielbassa
OBJECTIVE: To review the available literature in regard to the inflammatory process and pulpitis. Setting forth to evaluate if differences in the levels of various cytokines (TNF-α, IL-1β, IL-2, IL-6 and IL-8) can be observed in clinically diagnosed normal and irreversibly inflamed pulps that could serve as possible markers and/or diagnostic tools to predict and differentiate between certain states of inflammation. Methods used to measure and assess levels of cytokines have been limited to two protein quantification methods ELISA and/or Multiplex Array...
June 1, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28581920/randomized-clinical-trial-to-evaluate-mta-indirect-pulp-capping-in-deep-caries-lesions-after-24-months
#2
U Koc Vural, A Kiremitci, S Gokalp
OBJECTIVE: This clinical study aimed to assess the efficacies of mineral trioxide aggregate (MTA) and calcium hydroxide [Ca(OH)2] in the treatment of deep carious lesions by the direct complete caries removal technique. METHODS AND MATERIALS: A total of 100 permanent molar/premolar teeth were capped with either Ca(OH)2 (n=49) or MTA (n=51) and restored with composite resin in 73 patients. Periapical radiographs were acquired prior to the treatment as well as at six, 12, and 24 months posttreatment...
June 5, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28560802/the-effect-of-preoperative-oral-administration-of-prednisolone-on-postoperative-pain-in-patients-with-symptomatic-irreversible-pulpitis-a-single-centre-randomized-controlled-trial
#3
A Elkhadem, K Ezzat, M Ramadan, S AbdelGhaffar, D Khamis, A Said, A Abdel-Mawgoud, A Mamdouh, M AbouZeid, S Amin
AIM: This single-centre randomized, double-blind, placebo-controlled clinical trial assessed the effect of preoperative, single, oral dose of prednisolone on postoperative pain and postoperative analgesic intake in patients with symptomatic, irreversible pulpitis in mandibular molars. METHODOLOGY: Four hundred participants, randomly assigned into two equal groups, received either 40mg prednisolone or placebo tablets 30min before single-visit root canal treatment...
May 31, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28527838/pulp-inflammation-diagnosis-from-clinical-to-inflammatory-mediators-a-systematic-review
#4
REVIEW
Marjorie Zanini, Elisabeth Meyer, Stéphane Simon
INTRODUCTION: Similar to other tissues, the dental pulp mounts an inflammatory reaction as a way to eliminate pathogens and stimulate repair. Pulp inflammation is prerequisite for dentin pulp complex repair and regeneration; otherwise, chronic disease or pulp necrosis occurs. Evaluation of pulp inflammation severity is necessary to predict the clinical success of maintaining pulp vitality. Clinical limitations to evaluating in situ inflammatory status are well-described. A molecular approach that aids clinical distinction between reversible and irreversible pulpitis could improve the success rate of vital pulp therapy...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28513520/clinical-assessment-of-mineral-trioxide-aggregate-in-the-treatment-of-deep-carious-lesions
#5
U K Vural, A Kiremitçi, S Gökalp
OBJECTIVE: This clinical study aimed to assess the effectiveness of mineral trioxide aggregate (MTA) and calcium hydroxide (Ca[OH]2) in the treatment of deep carious lesions using the direct complete caries excavation technique. SUBJECTS AND METHODS: Hundred permanent molars/premolars were capped either with Ca (OH)2 (n = 49) or MTA (n = 51) and restored with composite resin in 73 patients. Periapical radiographs were taken prior to the treatment, at 6 months and 12 months...
May 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28512498/treatment-outcomes-of-full-pulpotomy-as-an-alternative-to-tooth-extraction-in-molars-with-hyperplastic-irreversible-pulpitis-a-case-report
#6
Saeed Asgary, Prashant Verma, Ali Nosrat
Root canal therapy (RCT) is a common and successful treatment for irreversible pulpitis due to carious pulp exposure in mature permanent teeth. However, it is often an expensive procedure, may require multiple appointments, and requires a high level of training and clinical skill, specifically in molars. Uninsured patients, low-income patients, and patients with limited access to specialist care often elect for extraction of restorable teeth with irreversible pulpitis. There is a need for an alternative affordable treatment option to preserve their teeth and maintain chewing function...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28509506/anti-inflammatory-and-regenerative-effects-of-albanian-propolis-in-experimental-vital-amputations
#7
Aida Meto, Agron Meto, Bora Bimbari, Kastriot Shytaj, Mutlu Özcan
This study evaluated the effects of Albanian propolis on the inflamed pulpal tissue after pulpotomy in piglets. In five piglets, two teeth each were infected using special pathogenic microbial flora that was prepared in advance in order to cause inflammation of the pulp. Pulpotomy was performed in the maxillary and mandibular central and lateral incisors. Microbial flora pathogenesis prepared from the section of infected teeth, containing Staphylococcus aureus, Streptococcus viridans, Enterococcus faecalis, Staphylococcus albus and mixed flora were used to cause artificial pulpitis...
September 2016: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28503480/intraoperative-discomfort-associated-with-the-use-of-a-rotary-or-reciprocating-system-a-prospective-randomized-clinical-trial
#8
Aline Cristine Gomes, Adriana Jesus Soares, Erick M Souza, Alexandre Augusto Zaia, Emmanuel João Nogueira Leal Silva
OBJECTIVES: The aim of this randomized, controlled, prospective clinical study was to evaluate patients' intraoperative discomfort during root canal preparations in which either multi-file rotary (Mtwo) or single-file reciprocating (Reciproc) systems were used. MATERIALS AND METHODS: Fifty-five adult patients, aged between 25 and 69 years old, with irreversible pulpitis or pulp necrosis participated in this study. Either the mesiobuccal or the distobuccal canals for maxillary molars and either the mesiobuccal or the mesiolingual canals for mandibular molars were randomly chosen to be instrumented with Mtwo multi-file rotary or Reciproc single-file reciprocating systems...
May 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28501071/in-patients-with-symptomatic-irreversible-pulpitis-articaine-is-3-6-times-more-efficacious-than-lidocaine-in-achieving-anesthetic-success-when-used-for-supplementary-infiltration-after-mandibular-block-anesthesia
#9
Mathilde C Peters, Tatiana M Botero
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Does articaine provide an advantage over lidocaine in patients with symptomatic irreversible pulpitis? A systematic review and meta-analysis. Kung J, McDonagh M, Sedgley CM. J Endod 2015; 41(11):1784-94. SOURCE OF FUNDING: The study was supported by the OHSU Department of Endodontology Les Morgan Endowment Fund and a resident research grant from the American Association of Endodontists Foundation TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data...
June 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28473980/oct4b1-regulates-the-cellular-stress-response-of-human-dental-pulp-cells-with-inflammation
#10
Lu Liu, Rong Huang, Ruiqi Yang, Xi Wei
Introduction. Infection and apoptosis are combined triggers for inflammation in dental tissues. Octamer-binding transcription factor 4-B1 (OCT4B1), a novel spliced variant of OCT4 family, could respond to the cellular stress and possess antiapoptotic property. However, its specific role in dental pulpitis remains unknown. Methods. To investigate the effect of OCT4B1 on inflammation of dental pulp cells (DPCs), its expression in inflamed dental pulp tissues and DPCs was examined by in situ hybridization, real-time PCR, and FISH assay...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28449751/preoperative-oral-ibuprofen-and-oxicam-analgesics-increase-the-rate-of-successful-anesthesia-of-mandibular-molars-with-irreversible-pulpitis
#11
Romina Brignardello-Petersen
No abstract text is available yet for this article.
May 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28437508/comparative-evaluation-of-anesthetic-efficacy-of-2-lidocaine-4-articaine-and-0-5-bupivacaine-on-inferior-alveolar-nerve-block-in-patients-with-symptomatic-irreversible-pulpitis-a-prospective-randomized-double-blind-clinical-trial
#12
Vivek Aggarwal, Mamta Singla, Sanjay Miglani
AIMS: To compare the anesthetic efficacy of 1.8 mL of 2% lidocaine with 1:200,000 epinephrine, 4% articaine with 1:100,000 epinephrine, and 0.5% bupivacaine with 1:200,000 epinephrine on producing inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis. METHODS: A total of 91 adult patients who were actively experiencing mandibular molar pain were involved in this study. The patients were randomly divided into three groups on the basis of the anesthetic solution used...
April 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28435378/differentiating-spontaneous-vertical-root-fracture-in-endodontically-treated-tooth
#13
Myung-Jin Lim, Jung-Ae Kim, Yoorina Choi, Chan-Ui Hong, Kyung-San Min
Although vertical root fracture (VRF) is mostly found in endodontically treated teeth, it also occurs spontaneously. If VRF is recognized after endodontic treatment, it is considered to be iatrogenic and can lead to legal trouble. However, legal problems can be averted if the dentist can prove that the VRF existed before endodontic treatment. This case report describes an unusual, spontaneous VRF in an endodontically treated tooth and presents a useful tip for determining whether a fracture is iatrogenic. We performed nonsurgical endodontic treatment on a mandibular first molar with irreversible pulpitis...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28417452/worldwide-pattern-of-antibiotic-prescription-in-endodontic-infections
#14
REVIEW
Juan José Segura-Egea, Jenifer Martín-González, María Del Carmen Jiménez-Sánchez, Isabel Crespo-Gallardo, Juan José Saúco-Márquez, Eugenio Velasco-Ortega
BACKGROUND: Odontogenic infections, and especially endodontic infections, are polymicrobial, involving a combination of Gram-positive and Gram-negative facultative anaerobes and strictly anaerobic bacteria. Therefore, antibiotics can be used as an adjunct to endodontic treatment. However, most chronic and even acute endodontic infections can be successfully managed by disinfection of the root-canal system, which eliminates the source of infection, followed by abscess drainage or tooth extraction, without the need for antibiotics...
April 17, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28416310/cracked-teeth-and-poor-oral-masticatory-habits-a-matched-case-control-study-in-china
#15
Feng Qiao, Min Chen, Xiaoli Hu, Kaijun Niu, Xu Zhang, Yanqiu Li, Zhou Wu, Zhengyan Shen, Ligeng Wu
INTRODUCTION: Previous studies have suggested that masticatory forces are associated with cracked teeth, but it is not clear which specific poor oral masticatory habits may be more likely to cause cracks. The aim of this study was to quantitatively assess risk factors for cracked teeth among poor oral masticatory habits and create a model for individualized risk predictions. METHODS: We enrolled 35 patients with cracked teeth matched to 70 controls without cracked teeth by age, sex, position of the affected tooth, presence/absence of systemic disease, and diagnosis of symptomatic irreversible pulpitis from the Stomatology Hospital of Tianjin Medical University, Tianjin, China...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28416306/histologic-findings-of-a-human-immature-revascularized-regenerated-tooth-with-symptomatic-irreversible-pulpitis
#16
Chufang Peng, Yuming Zhao, Wenjun Wang, Yuan Yang, Man Qin, Lihong Ge
INTRODUCTION: Pulp revascularization/regeneration in immature permanent teeth with necrotic pulp and/or apical periodontitis is an effective approach for inducing root maturation. Previous histologic studies showed cementoid/osteoid tissue and/or periodontal ligament-like tissue formed within the root canals. This case report describes the histologic findings of a human symptomatic irreversible pulpitis immature permanent tooth with most of the pulp removed after a revascularization/regeneration procedure...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28407420/dental-biofilm-infections-an-update
#17
REVIEW
Tove Larsen, Nils-Erik Fiehn
Teeth are colonized by oral bacteria from saliva containing more than 700 different bacterial species. If removed regularly, the dental biofilm mainly comprises oral streptococci and is regarded as resident microflora. But if left undisturbed, a complex biofilm containing up to 100 bacterial species at a site will build up and may eventually cause development of disease. Depending on local ecological factors, the composition of the dental biofilm may vary considerably. With access to excess carbohydrates, the dental biofilm will be dominated by mainly gram-positive carbohydrate-fermenting bacteria causing demineralization of teeth, dental caries, which may further lead to inflammation and necrosis in the pulp and periapical region, i...
April 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28399652/facial-presentations-of-primary-headache-disorders
#18
Yair Sharav, Zaza Katsarava, Andrew Charles
Background Many patients with mid-face or lower face craniofacial pain are diagnosed, based on accompanying signs and symptoms and features other than location, as either atypical migraines or atypical TACs. Distinguishing features of headache disorders as a cause of facial pain include the temporal pattern of pain, associated symptoms including light and sound sensitivity and nausea, cranial autonomic symptoms, and the lack of local triggering among others. Results An intraoral neurovascular pain has been observed, and was termed neurovascular orofacial pain (NVOP)...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28383600/perception-of-discomfort-during-injection-and-the-need-for-supplemental-anesthesia-in-the-intraosseous-technique-using-4-articaine
#19
Adel Martínez Martínez, María Del Pilar Lujan Pardo, Jonathan Harris Ricardo
The authors conducted an experimental study to determine patient perception of discomfort during injection and the need for supplemental anesthesia using the intraosseous technique with 4% articaine with 1:100,000 epinephrine in patients with symptomatic pulpitis in mandibular molars. At different clinical sessions, researchers used 4% articaine with 1:100,000 epinephrine to apply intraosseous injection (Group 1) or inferior alveolar nerve block (Group 2). Each technique was applied in 35 patients. In each group, the need for additional anesthesia was determined and patient discomfort during injection was assessed with a Visual Analogue Scale (VAS) test...
December 2016: Acta Odontológica Latinoamericana: AOL
https://www.readbyqxmd.com/read/28377925/isolation-of-mesenchymal-stem-cells-from-human-deciduous-teeth-pulp
#20
Aileen I Tsai, Hsiang-Hsi Hong, Wey-Ran Lin, Jen-Fen Fu, Chih-Chun Chang, I-Kuan Wang, Wen-Hung Huang, Cheng-Hao Weng, Ching-Wei Hsu, Tzung-Hai Yen
This study aimed to identify predictors of success rate of mesenchymal stem cell (MSC) isolation from human deciduous teeth pulp. A total of 161 deciduous teeth were extracted at the dental clinic of Chang Gung Memorial Hospital. The MSCs were isolated from dental pulps using a standard protocol. In total, 128 colonies of MSCs were obtained and the success rate was 79.5%. Compared to teeth not yielding MSCs successfully, those successfully yielding MSCs were found to have less severe dental caries (no/mild-to-moderate/severe: 63...
2017: BioMed Research International
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