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Pulpitis

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https://www.readbyqxmd.com/read/29028630/ezh2-regulates-dental-pulp-inflammation-by-direct-effect-on-inflammatory-factors
#1
Tianqian Hui, Peng A, Yuan Zhao, Jing Yang, Ling Ye, Chenglin Wang
OBJECTIVE: Pulpitis is a multi-factorial disease that could be caused by complex interactions between genetics, epigenetics and environmental factors. We aimed to evaluate the role of Enhancer of Zeste Homolog 2 (EZH2) in the inflammatory response of human dental pulp cells (HDPCs) and dental pulp tissues. METHODS: The expressions of inflammatory cytokines in HDPCs treated by EZH2 complex or EZH2 siRNA with or without rhTNF-α were examined by quantitative real-time polymerase chain reaction (q-PCR)...
October 7, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28920780/use-of-composite-materials-as-a-component-of-tusk-fracture-management-in-an-asian-elephant-elephas-maximus-and-an-african-elephant-loxodonta-africana
#2
Richard R Sim, Elizabeth Stringer, Dennis Donovan, Rachael Chappell, Pat Flora, Jon Hall, Selvum Pillay, Benjamin G Willis, Stephanie McCain
Tusk fractures in Asian (Elephas maximus) and African elephants (Loxodonta africana) can result in damage to the distal end or to longitudinal cracks, potentially progressing to pulpitis. With pulp exposure, endodontic therapy is the treatment of choice, but conservative therapy has sufficed for some elephants. This manuscript describes the use of composite materials as a component of tusk fracture management. A 7-yr-old male Asian elephant fractured the distal end of both tusks with pulp exposure in one. Capping of each tusk with a Kevlar/fiberglass composite prevented further damage, and a modification allowed care of the exposed pulp tissue...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920110/painful-neuropathy-caused-by-compression-of-the-inferior-alveolar-nerve-by-focal-osteosclerotic-lesion-of-the-mandible-a-case-report
#3
David Debevc, Tomaž Hitij, Andrej Kansky
Osteosclerotic lesions are a common finding on dental radiographs. They are considered developmental variants of a normal bone architecture and they usually do not need any treatment. The purpose of this article is to present a rare case of osteosclerotic lesion of the mandible causing trigeminal neuropathy by compression of the alveolar nerve. The pain started with dental hypersensitivity of the mandibular right first molar. Later on, signs of irreversible molar tooth pulpitis developed. Endodontic therapy and apicoectomy did not resolve the pain, which later intensified, and painful neuropathy localized to inferior alveolar nerve developed; therefore, surgical decompression was indicated...
2017: Quintessence International
https://www.readbyqxmd.com/read/28894386/oxidative-stress-in-patients-with-endodontic-pathologies
#4
Veiko Vengerfeldt, Reet Mändar, Mare Saag, Anneli Piir, Tiiu Kullisaar
BACKGROUND: Apical periodontitis (AP) is an inflammatory disease affecting periradicular tissues. It is a widespread condition but its etiopathogenetic mechanisms have not been completely elucidated and the current treatment options are not always successful. PURPOSE: To compare oxidative stress (OxS) levels in the saliva and the endodontium (root canal [RC] contents) in patients with different endodontic pathologies and in endodontically healthy subjects. PATIENTS AND METHODS: The study group of this comparison study included 22 subjects with primary chronic apical periodontitis (pCAP), 26 with posttreatment or secondary chronic apical periodontitis (sCAP), eight with acute periapical abscess, 13 with irreversible pulpitis, and 17 healthy controls...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28857203/assessment-of-alternative-emergency-treatments-for-symptomatic-irreversible-pulpitis-a-randomized-clinical-trial
#5
B Eren, E O Onay, M Ungor
AIM: To evaluate three emergency procedures for their ability to alleviate clinical symptoms associated with symptomatic teeth having signs of (at least) partial irreversible pulpitis. METHODOLOGY: Sixty-six maxillary and mandibular molars were randomly assigned to a total pulpectomy group (TP; n=22), partial pulpectomy group (PP; n=22), or pulpotomy group (P; n=22). Procedure durations were recorded. Patients answered a questionnaire on daily analgesic requirements and about clinical symptoms (pain intensity, chewing sensitivity, and thermal sensitivity) after the anaesthetic effect had disappeared (Day 0) and on Days 1, 3, and 7 post-treatment...
August 30, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28855754/clinical-evaluation-of-mineral-trioxide-aggregate-and-biodentine-as-direct-pulp-capping-agents-in-carious-teeth
#6
Swaroop Hegde, B Sowmya, Sylvia Mathew, Shilpa H Bhandi, Shruthi Nagaraja, K Dinesh
BACKGROUND: Root canal treatment has been a routine treatment option for carious exposure of the dental pulp. In the context of minimally invasive dentistry, direct pulp capping (DPC) procedure with a reliable biomaterial may be considered as an alternative provided the pulp status is favorable. Mineral trioxide aggregate (MTA), a bioactive cement with excellent sealing ability and biocompatibility is capable of regenerating relatively damaged pulp and formation of dentin bridge when used as DPC agent...
March 2017: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/28844305/regenerative-endodontics-for-adult-patients
#7
Ling He, Sahng G Kim, Qimei Gong, Juan Zhong, Sainan Wang, Xuedong Zhou, Ling Ye, Junqi Ling, Jeremy J Mao
The goal of endodontics is to save teeth. Since inception, endodontic treatments are performed to obturate disinfected root canals with inert materials such as gutta-percha. Although teeth can be saved after successful endodontic treatments, they are devitalized and therefore susceptible to reinfections and fractures. The American Association of Endodontists (AAE) has made a tremendous effort to revitalize disinfected immature permanent teeth in children and adolescents with diagnoses including pulp necrosis or apical periodontitis...
September 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28829993/effect-of-different-dental-burs-for-experimental-induction-of-pulpitis-in-mice
#8
Xilin Shi, Zhengmao Li, Ying He, Qianzhou Jiang, Xuechao Yang
OBJECTIVE: To evaluate the effect of using different dental burs on the development of pulpal inflammation after pulpal exposure in mice. DESIGN: Eighty-eight C57BL/6 mice were randomly assigned to group A (n=40), group B (n=40) and control group (n=8). The pulps of the maxillary first molars were occlusally exposed using ¼ round burs and polishing burs in group A and B respectively. Animals were sacrificed randomly at 0h, 4h, 8h, 12h and 24h after pulpal exposure...
August 11, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28808468/treatment-of-a-maxillary-second-molar-with-one-buccal-and-two-palatal-roots-confirmed-with-cone-beam-computed-tomography
#9
Masoud Parirokh, Mahsa Razifar, Hamed Manochehrifar, Paul V Abbott, Nima Hatami, Nargessaddat Kashi, Aida Farhadi
Root canal configuration is an important subject in endodontic practice and dentists should be familiar with all possible types of root canal configuration. A forty-three year old male was referred for root canal treatment of his maxillary left second molar tooth with symptomatic irreversible pulpitis. Pre-operative radiographs showed a three rooted molar. However, after access cavity preparation two palatal and one buccal orifices were detected. The patient was informed of the unusual root canal anatomy and cone-beam computed tomography (CBCT) was ordered for precise evaluation of the anatomy...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28790964/numb-chin-syndrome-leading-to-a-diagnosis-of-salivary-ductal-adenocarcinoma-a-case-report-and-review-of-the-literature
#10
Lei Wu, Yifan Zheng, Zhou Zhou, Yanmei Liu, Weixi Zhang, Qi Wu
Numb chin syndrome (NCS) refers to a rare sensory neuropathy characterized by numbness of the chin within the distribution of the mental or inferior alveolar nerve. Although NCS is usually caused by a benign process, it should not be underestimated and a thorough diagnostic evaluation for a new or known progressive malignancy should always be performed. Here, we report a case of salivary ductal adenocarcinoma that mimicked a pulpitis and periodontitis in its early presentation accompanied by numbness of chin...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28776717/minimally-invasive-endodontics-a-new-diagnostic-system-for-assessing-pulpitis-and-subsequent-treatment-needs
#11
EDITORIAL
W J Wolters, H F Duncan, P L Tomson, I E Karim, G McKenna, M Dorri, L Stangvaltaite, L W M van der Sluis
No abstract text is available yet for this article.
September 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28754406/antibiotic-use-in-2016-by-members-of-the-american-association-of-endodontists-report-of-a-national-survey
#12
Mark Germack, Christine M Sedgley, Wael Sabbah, Brian Whitten
INTRODUCTION: This study surveyed the antibiotic prescribing practices of endodontists, and data were compared with previous surveys conducted in 1994 and 1999. METHODS: A 17-question survey was sent via www.surveymonkey.com to 3000 active members of the American Association of Endodontists for responses about antibiotic prescribing practices and demographics. The data were analyzed using descriptive statistics, chi-square tests, and linear regression analyses...
October 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28748395/variation-in-caries-treatment-proposals-among-dentists-in-norway-the-best-interest-of-the-child
#13
A Rønneberg, A B Skaare, B Hofmann, I Espelid
AIM: To explore variation in treatment-related-decisions for severe caries in children among dentists in the Public Dental Service (PDS) in Norway. It was also to evaluate the treatment choices in relation to the best interest of children and a child's rights to enjoy the highest standard of health care. METHODS: A pre-coded questionnaire was sent electronically to all general dental practitioners (GDPs) working in the PDS in eight counties in Norway (n = 611)...
July 26, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28736921/supplementary-techniques-for-pain-control-during-root-canal-treatment-of-lower-posterior-teeth-with-irreversible-pulpitis-a-systematic-review-and-meta-analysis
#14
Pinpana Tupyota, Pattama Chailertvanitkul, Malinee Laopaiboon, Chetta Ngamjarus, Paul V Abbott, Suttichai Krisanaprakornkit
The purpose of this systematic review and meta-analysis was to evaluate utilisation of supplementary techniques for pain control during root canal treatment of lower molars with irreversible pulpitis. The literature was searched using electronic databases up to year 2012. Seventeen studies with 1504 participants were included and each study compared experimental interventions with a standard treatment, i.e. the inferior alveolar nerve block. Changing the injection techniques or supplemental injection had no significant effect on pulp anaesthesia compared to the standard treatment (P = 1...
July 24, 2017: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/28728750/trigeminocardiac-reflex-during-non-surgical-root-canal-treatment-of-teeth-with-irreversible-pulpitis
#15
James I-Sheng Huang, Hao-Hueng Chang, Chun-Pei Lin, Wan-Chuen Liao, Chia-Tze Kao, Tsui-Hsien Huang
BACKGROUND/PURPOSE: Trigeminocardiac reflex (TCR) is a unique clinical incident of acute change in hemodynamic balance, which may lead to hypotension, bradycardia, and even clinical crisis. Up to date, no study so far considers the impact of non-surgical root canal treatment (NSRCT) of irreversible pulpitis teeth under either local infiltration or block anesthesia on hemodynamic change possibly related to TCR. METHODS: This study enrolled 111 patients with 138 irreversible pulpitis teeth that were treated by two sessions of NSRCT...
July 17, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28694714/sensitivity-specificity-predictive-values-and-accuracy-of-three-diagnostic-tests-to-predict-inferior-alveolar-nerve-blockade-failure-in-symptomatic-irreversible-pulpitis
#16
Daniel Chavarría-Bolaños, Laura Rodríguez-Wong, Danny Noguera-González, Vicente Esparza-Villalpando, Mauricio Montero-Aguilar, Amaury Pozos-Guillén
INTRODUCTION: The inferior alveolar nerve block (IANB) is the most common anesthetic technique used on mandibular teeth during root canal treatment. Its success in the presence of preoperative inflammation is still controversial. The aim of this study was to evaluate the sensitivity, specificity, predictive values, and accuracy of three diagnostic tests used to predict IANB failure in symptomatic irreversible pulpitis (SIP). METHODOLOGY: A cross-sectional study was carried out on the mandibular molars of 53 patients with SIP...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28693407/patterns-of-drugs-prescribed-for-dental-outpatients-in-nigeria-findings-and-implications
#17
Joseph O Fadare, Kazeem A Oshikoya, Obitade S Obimakinde, Abayomi O Sijuade, Jide M Afolayan, Adeyinka A Adeleke, Brian Godman, Damilola O Ojumu
OBJECTIVES: There are concerns with inappropriate prescribing of medicines among dentists especially antimicrobials. It is more concerning if this increases resistance rates. This study aimed to address this by assessing patterns of drugs prescribed for outpatients attending a hospital dental clinic in Nigeria. The findings will be used to plan future interventions, particularly around antimicrobial prescribing, where there are concerns. METHODS AND MATERIALS: Medical records of patients attending the dental clinic of a leading teaching hospital in Nigeria were evaluated...
July 11, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28685563/allergic-contact-dermatitis-to-acrylates
#18
P Romita, C Foti, L Masciopinto, E Nettis, E Di Leo, G Calogiuri, D Bonamonte, G Angelini, G Dipalma, A Ballini, F Inchingolo
Acrylates and methacrylates are a large group of chemically reactive monomers that are polymerized into acrylic plastics. These have very broad applications in glues, coatings and various plastic materials. Allergic contact dermatitis (ACD) caused by acrylates can be occupational, mainly in dentistry workers during the manufacturing and implantation of dental prosthesis, and in nail technicians during the sculpturing and application of artificial nails. The clinical manifestations vary according to the location of the contact...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28673494/partial-pulpotomy-in-mature-permanent-teeth-with-clinical-signs-indicative-of-irreversible-pulpitis-a-randomized-clinical-trial
#19
Nessrin A Taha, Mohammad A Khazali
INTRODUCTION: This study aimed to assess the outcome of partial pulpotomy using mineral trioxide aggregate (MTA) compared with calcium hydroxide (CH) in mature cariously exposed permanent molars. METHODS: Fifty permanent molar teeth with carious exposures in 50 patients >20 years old were included. Preoperative pulpal and periapical diagnosis was established based on a history of presenting pain, results of cold testing, and radiographic findings. After informed consent, the tooth was anesthetized, isolated via a dental dam, and disinfected with 5% sodium hypochlorite before caries excavation...
September 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28600966/inflammatory-cytokines-in-normal-and-irreversibly-inflamed-pulps-a-systematic-review
#20
REVIEW
Vivian Hirsch, Michael Wolgin, Aleksandr V Mitronin, Andrej M Kielbassa
OBJECTIVE: To review the available literature in regard to the inflammatory process and pulpitis. Setting forth to evaluate if differences in the levels of various cytokines (TNF-α, IL-1β, IL-2, IL-6 and IL-8) can be observed in clinically diagnosed normal and irreversibly inflamed pulps that could serve as possible markers and/or diagnostic tools to predict and differentiate between certain states of inflammation. Methods used to measure and assess levels of cytokines have been limited to two protein quantification methods ELISA and/or Multiplex Array...
October 2017: Archives of Oral Biology
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