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Vagal nerve

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https://www.readbyqxmd.com/read/29154689/peripheral-vagal-nerve-stimulation-modulates-the-nociceptive-withdrawal-reflex-in-healthy-subjects-a-randomized-cross-over-sham-controlled-study
#1
Roberto De Icco, Daniele Martinelli, Vito Bitetto, Mauro Fresia, Eric Liebler, Giorgio Sandrini, Cristina Tassorelli
Introduction The mechanism of action of non-invasive vagal nerve stimulation in the treatment of migraine is elusive. We studied its effect in a human model of pain, the nociceptive withdrawal reflex. Methods We enrolled 10 healthy subjects who underwent active non-invasive vagal nerve stimulation and sham treatment in a randomized, cross-over, sham-controlled study. Non-invasive vagal nerve stimulation was delivered with gammaCore®. The assessment of the nociceptive withdrawal reflex was performed at baseline (T0) and at 5 (T5) and 30 (T30) minutes after stimulation...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29150643/%C3%AE-eudesmol-an-oxygenized-sesquiterpene-stimulates-appetite-via-trpa1-and-the-autonomic-nervous-system
#2
Kazuaki Ohara, Takafumi Fukuda, Yuko Ishida, Chika Takahashi, Rena Ohya, Mikio Katayama, Kunitoshi Uchida, Makoto Tominaga, Katsuya Nagai
Transient receptor potential ankyrin 1 (TRPA1) is a calcium-permeable non-selective cation channel, which is activated by various noxious or irritant substances in nature. TRPA1 activators have been generally recognized as noxious, however, foods and beverages containing TRPA1 activators are preferably consumed; the reasons for this discrepancy are not well understood. We demonstrate that TRPA1 is involved in the stimulatory appetite control mechanism. β-Eudesmol is an oxygenated sesquiterpene contained in medicinal or edible plants which activates TRPA1...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29130228/-valuation-and-prospect-of-function-preserving-gastrectomy
#3
Shuchang Wang, Site Yu, Jia Xu, Gang Zhao
Preserving gastric function and improving quality of life (QOL) is the tendency of surgery for early gastric cancer. Function preserving gastrectomy (FPG) is applied to modify the extent of surgery and to achieve better quality of life at the premise of radical resection. Pylorus-preserving gastrectomy is the most favorable approach of FPG with oncological safety, which can improve nutritional status and QOL via preserving pylorus and vagal nerve. Proximal gastrectomy is widely accepted as FPG for early upper 1/3 gastric cancer...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29128975/transcutaneous-vagus-nerve-stimulation-tvns-modulates-flow-experience
#4
Lorenza S Colzato, Gina Wolters, Corinna Peifer
Flow has been defined as a pleasant psychological state that people experience when completely absorbed in an activity. Previous correlative evidence showed that the vagal tone (as indexed by heart rate variability) is a reliable marker of flow. So far, it has not yet been demonstrated that the vagus nerve plays a causal role in flow. To explore this we used transcutaneous vagus nerve stimulation (tVNS), a novel non-invasive brain stimulation technique that increases activation of the locus coeruleus (LC) and norepinephrine release...
November 11, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29127549/preservation-of-the-celiac-branch-of-the-vagal-nerve-for-pylorus-preserving-gastrectomy-is-it-meaningful
#5
Haruna Furukawa, Manabu Ohashi, Michitaka Honda, Koshi Kumagai, Souya Nunobe, Takeshi Sano, Naoki Hiki
BACKGROUND: Preserving the hepatic and pyloric branches of the vagal nerve in laparoscopic pylorus-preserving gastrectomy (LPPG) is considered necessary to maintain the function of the pyloric cuff. However, the clinical benefits of preservation of the celiac branch of the vagal nerve (CBVN) remain unclear. METHODS: Of 391 patients who underwent LPPG for early gastric cancer, 116 patients in whom the CBVN was preserved (CBP group) and 58 patients in whom it was not preserved (non-CBP group) were selected through the propensity score-matching method...
November 10, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29110082/continuous-monitoring-of-the-recurrent-laryngeal-nerve
#6
Aitor De la Quintana Basarrate, Arantza Iglesias Martínez, Iciar Salutregui, Leire Agirre Etxabe, Ainhoa Arana González, Izaskun Yurrebaso Santamaría
OBJECTIVE: The objective of this study was to assess the safety and utility of continuous intraoperative neuromonitoring for the prevention of recurrent laryngeal nerve injury during thyroidectomy. METHODS: A prospective cohort study was conducted in consecutive patients undergoing thyroidectomy. Variations in amplitude and distal latency of the electromyogram (EMG) were assessed. In the case of suspicious events, restorative manoeuvers were performed to attempt to recover the potentials...
November 6, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29101567/vagus-nerve-preserving-versus-conventional-laparoscopic-splenectomy-and-azygoportal-disconnection
#7
Dou-Sheng Bai, Ping Chen, Sheng-Jie Jin, Jian-Jun Qian, Guo-Qing Jiang
BACKGROUND: Conventional open and conventional laparoscopic splenectomy and azygoportal disconnection (CLSD) result in poor quality of life because of damage to the vagal nerve. We have developed vagus nerve-preserving laparoscopic splenectomy and azygoportal disconnection (VLSD). This study aimed to evaluate whether VLSD is effective and safe, and to determine whether a reduction in the incidence of postoperative complications improves postoperative quality of life compared with CLSD...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29081397/long-term-intermittent-high-amplitude-subcutaneous-nerve-stimulation-reduces-sympathetic-tone-in-ambulatory-dogs
#8
Yuan Yuan, Zhaolei Jiang, Ye Zhao, Wei-Chung Tsai, Jheel Patel, Lan S Chen, Changyu Shen, Shien-Fong Lin, Huei-Sheng Vincent Chen, Thomas H Everett, Michael C Fishbein, Zhenhui Chen, Peng-Sheng Chen
BACKGROUND: Reducing sympathetic efferent outflow from the stellate ganglia (SG) may be antiarrhythmic. OBJECTIVE: To test the hypothesis that chronic thoracic subcutaneous nerve stimulation (ScNS) could reduce SG nerve activity (SGNA) and control paroxysmal atrial tachycardia (PAT). METHODS: We performed thoracic ScNS in 8 dogs while monitoring the SGNA, vagal nerve activity (VNA) and subcutaneous nerve activity (ScNA). An additional 3 dogs were used for sham stimulation as controls...
October 25, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29080623/relationship-between-abnormal-vagus-nerve-tension-and-basal-ganglia-cerebral-infarction-induced-paroxysmal-atrial-fibrillation
#9
Wen-Bo Cheng, Dong Li, Qin Yang, Yue-Mei Hou
OBJECTIVE: To investigate the relationship between basal ganglia cerebral infarction and paroxysmal atrial fibrillation (PAF) caused by abnormal vagus nerve tension. METHODS: A total of 1483 cases of elder patients with cerebral infarction who received head CT or MRI examination during the period were enrolled, including 830 male and 613 female, with the average age as 78 years. These cases were divided into basal infarction ganglia group (n = 1045) and non-basal ganglia infarction group (n = 438) according to the anatomic site of cerebral infarction...
September 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29078343/dual-origin-of-enteric-neurons-in-vagal-schwann-cell-precursors-and-the-sympathetic-neural-crest
#10
Isabel Espinosa-Medina, Ben Jevans, Franck Boismoreau, Zoubida Chettouh, Hideki Enomoto, Thomas Müller, Carmen Birchmeier, Alan J Burns, Jean-François Brunet
Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonization, which brings enteric precursors into the foregut. Here we show that the "vagal crest" subsumes two populations of enteric precursors with contrasted origins, initial modes of migration, and destinations. Crest cells adjacent to somites 1 and 2 produce Schwann cell precursors that colonize the vagus nerve, which in turn guides them into the esophagus and stomach...
October 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29071894/-effect-of-electroacupuncture-stimulation-of-heart-meridian-on-autonomic-nervous-activities-in-acute-myocardial-ischemia-rats
#11
Shuai Cui, Jing Xu, Jie Wang, Sheng-Bing Wu, Yi-Ping Zhou, Mei-Qi Zhou
OBJECTIVE: To observe the effect of electroacupuncture (EA) stimulation of the Heart Meridian on electrical activities of neck sympathetic and vagal nerves in acute myocardial ischemia (AMI) rats. METHODS: Thirty SD rats were randomly divided into 3 groups, sham operation (sham), model and EA(n=10 rats in each group). The left anterior descending branch (LADB) of the coronary artery was occluded to make an acute myocardial ischemia (AMI) model.For rats of the sham group, a surgical suture was simply threaded beneath the LADB without ligation...
December 25, 2016: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29070631/the-k%C3%A3-lliker-fuse-orchestrates-the-timing-of-expiratory-abdominal-nerve-bursting
#12
William H Barnett, Sarah E M Jenkin, William K Milsom, Julian F R Paton, Ana P L Abdala, Yaroslav I Molkov, Daniel B Zoccal
Coordination of respiratory pump and valve muscle activity is essential for normal breathing. A hallmark respiratory responses to hypercapnia and hypoxia is the emergence of active exhalation, characterized by abdominal muscle pumping during the late one-third of expiration (late-E phase). Late-E abdominal activity during hypercapnia has been attributed to the activation of expiratory neurons located within the parafacial respiratory group (pFRG). However, the mechanisms that control emergence of active exhalation, and its silencing in restful breathing, are not completely understood...
October 25, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29063106/-recent-progress-of-mitochondrial-quality-control-in-ischemic-heart-disease-and-its-role-in-cardio-protection-of-vagal-nerve
#13
Run-Qing Xue, Man Xu, Xiao-Jiang Yu, Long-Zhu Liu, Wei-Jin Zang
Ischemic heart disease (IHD) is the life-threatening cardiovascular disease. Mitochondria have emerged as key participants and regulators of cellular energy demands and signal transduction. Mitochondrial quality is controlled by a number of coordinated mechanisms including mitochondrial fission, fusion and mitophagy, which plays an important role in maintaining healthy mitochondria and cardiac function. Recently, dysfunction of each process in mitochondrial quality control has been observed in the ischemic hearts...
October 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/29060853/the-challenge-of-magnetic-vagal-nerve-stimulation-for-myocardial-infarction-preliminary-clinical-trial
#14
Takuya Nishikawa, Keita Saku, Koji Todaka, Yukimitsu Kuwabara, Shinobu Arai, Takuya Kishi, Tomomi Ide, Hiroyuki Tsutsui, Kenji Sunagawa
Numerous studies have shown in animal models that vagal nerve stimulation (VNS) strikingly reduces infarct size of acute myocardial infarction (AMI) and prevents heart failure. However, the lack of techniques to noninvasively stimulate the vagal nerve hinders VNS from clinical applications. Transcranial magnetic stimulation is noninvasive and capable of stimulating central neurons in patients. In this study, we examined whether the magnetic stimulation could noninvasively activate the cervical vagal nerve in healthy human...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060561/respiratory-gated-auricular-vagal-afferent-nerve-stimulation-ravans-effects-on-autonomic-outflow-in-hypertension
#15
Roberta Sclocco, Ronald G Garcia, Aileen Gabriel, Norman W Kettner, Vitaly Napadow, Riccardo Barbieri
Transcutaneous stimulation of the auricular branch of the vagus nerve (ABVN) has been proposed as a non-invasive alternative to vagus nerve stimulation (VNS). However, its cardiovagal effects are inconsistent across studies, likely due to inhomogeneity in the stimulation parameters. Here, we evaluate respiratory-gated ABVN stimulation (Respiratory-gated Auricular Vagal Afferent Nerve Stimulation, RAVANS), where the stimuli are delivered in 1 s bursts during the exhalation phase of respiration, thus mimicking the breathing-induced modulation of cardiac vagal activity...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059589/high-frequency-burst-vagal-nerve-simulation-therapy-in-a-natural-primate-model-of-genetic-generalized-epilepsy
#16
C Á Szabó, F S Salinas, A M Papanastassiou, J Begnaud, M Ravan, K S Eggleston, R Shade, C Lutz, M De La Garza
PURPOSE: Since the approval of Vagal Nerve Stimulation (VNS) Therapy for medically refractory focal epilepsies in 1997, it has been also reported to be effective for a wide range of generalized seizures types and epilepsy syndromes. Instead of conventional VNS Therapy delivered at 20-30Hz signal frequencies, this study evaluates efficacy and tolerability of high-frequency burst VNS in a natural animal model for genetic generalized epilepsy (GGE), the epileptic baboon. METHODS: Two female baboons (B1 P...
October 12, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29057372/do-the-psychological-effects-of-vagus-nerve-stimulation-partially-mediate-vagal-pain-modulation
#17
Eleni Frangos, Emily A Richards, M Catherine Bushnell
There is preclinical and clinical evidence that vagus nerve stimulation modulates both pain and mood state. Mechanistic studies show brainstem circuitry involved in pain modulation by vagus nerve stimulation, but little is known about possible indirect descending effects of altered mood state on pain perception. This possibility is important, since previous studies have shown that mood state affects pain, particularly the affective dimension (pain unpleasantness). To date, human studies investigating the effects of vagus nerve stimulation on pain perception have not reliably measured psychological factors to determine their role in altered pain perception elicited by vagus nerve stimulation...
January 2017: Neurobiol Pain
https://www.readbyqxmd.com/read/29044022/-villaret-syndrome-and-lung-adenocarcinoma-an-unusual-association
#18
Juan José Canciani, Juliana A Ospina, Paula Acosta, Javier López, Agustín Dal Verme, Christian Peralta
Villaret syndrome is defined by the affection of the glossopharyngeal (IX), vagal (X), accessory (XI) and hypoglossal (XII) cranial nerves associated with ipsilateral Horner syndrome. It is caused by the compression of these nerves and the neighboring sympathetic plexus fibers at the base of the skull, particularly in the retroparotid space. Even though the invasion of the central nervous system in patients with advanced lung cancer is a frequent and well known occurrence, this particular symptomatic association is extremely rare...
2017: Medicina
https://www.readbyqxmd.com/read/29035775/avoiding-the-pocket-a-case-report-of-coiling-of-distal-shunt-catheter-into-subcutaneous-pocket
#19
Richard Justin Garling, Sandeep Sood, Carolyn Anne Harris
INTRODUCTION: Hydrocephalus is one of the most common disorders of neurosurgery and ventricular shunting, the primary surgical intervention, malfunctions in 85% of patients by 10 years. PRESENTATION OF CASE: Here we present a case of a 12-year-old girl with history of a vagal nerve stimulator (VNS) and ventricular shunt, most recently revised from ventriculoatrial (VA) to ventriculoperitoneal (VP) shunt at an outside hospital. The patient presented with a new left chest bulge, nausea, emesis, and seizures...
October 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29031749/vagal-nerve-stimulator-induced-chin-electromyography-artifact
#20
Pradeep C Bollu, Sivaraman Manjamalai
No abstract text is available yet for this article.
October 2017: Sleep Medicine
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