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milk and cardiovascular disease

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https://www.readbyqxmd.com/read/27894411/allele-specific-pcr-and-melting-curve-analysis-showed-relatively-high-frequency-of-%C3%AE-casein-gene-a1-allele-in-iranian-holstein-simmental-and-native-cows
#1
M Gholami, S H Hafezian, G Rahimi, A Farhadi, Z Rahimi, D Kahrizi, S Kiani, H Karim, S Vaziri, S Muhammadi, F Veisi, K Ghadiri, H Shetabi, J Zargooshi
There are two allelic forms of A1 and A2 of β-casein gene in dairy cattle. Proteolytic digestion of bovine β-casein A1 type produces bioactive peptide of β-casomorphin-7 known as milk devil. β-casomorphin-7 causes many diseases, including type 1 diabetes, cardiovascular disease syndrome, sudden death and madness. The aim of the present study was to determine the different allelic forms of β-casein gene in Iranian Holstein, Simmental and native cattle in order to identify A1 and A2 variants. The blood samples were collected randomly and DNA was extracted using modified salting out method...
October 31, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/27882862/milk-and-dairy-products-good-or-bad-for-human-health-an-assessment-of-the-totality-of-scientific-evidence
#2
REVIEW
Tanja Kongerslev Thorning, Anne Raben, Tine Tholstrup, Sabita S Soedamah-Muthu, Ian Givens, Arne Astrup
BACKGROUND: There is scepticism about health effects of dairy products in the public, which is reflected in an increasing intake of plant-based drinks, for example, from soy, rice, almond, or oat. OBJECTIVE: This review aimed to assess the scientific evidence mainly from meta-analyses of observational studies and randomised controlled trials, on dairy intake and risk of obesity, type 2 diabetes, cardiovascular disease, osteoporosis, cancer, and all-cause mortality...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27853717/amiata-donkey-milk-chain-animal-health-evaluation-and-milk-quality
#3
Giuseppe Ragona, Franco Corrias, Martina Benedetti, Maria Paladini, Federica Salari, Lolanda Altomonte, Mina Martini
This study presents an investigation of Amiata donkey health and quality of milk for human consumption. Thirty-one lactating dairy jennies were examined. The following samples were collected: faecal samples from the rectum of animals for parasitological examination; cervical swabs for the detection of bacteria causing reproductive disorders; and blood samples for serological diagnosis of main zoonotic (Brucella spp., Leptospira spp.) and donkey abortion agents (Brucella spp., Leptospira spp., Salmonella abortus equi, Equine viral arterithis virus, Equine herpesvirus type 1)...
June 3, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/27825722/current-status-of-hiv-aids-in-the-art-era
#4
REVIEW
Kazuhisa Yoshimura
Human immunodeficiency virus (HIV) spread to humans from chimpanzees (HIV-1 groups M and N), gorillas (HIV-1 groups P and O), and sooty mangabeys (HIV-2). HIV is spread mainly through blood or body fluids. Subjects can become infected with HIV by sexual contact, needle sharing, blood transfusions, or maternal transmissions as a blood-borne virus or via breast-milk. The incubation period of HIV-1 from infection to the development of AIDS ranges from 8 to 11 years. In the past 3 decades, HIV has caused a great burden to global wealth and health...
November 5, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/27797709/whey-protein-lowers-blood-pressure-and-improves-endothelial-function-and-lipid-biomarkers-in-adults-with-prehypertension-and-mild-hypertension-results-from-the-chronic-whey2go-randomized-controlled-trial
#5
Ágnes A Fekete, Carlotta Giromini, Yianna Chatzidiakou, D Ian Givens, Julie A Lovegrove
BACKGROUND: Cardiovascular diseases (CVDs) are the greatest cause of death globally, and their reduction is a key public-health target. High blood pressure (BP) affects 1 in 3 people in the United Kingdom, and previous studies have shown that milk consumption is associated with lower BP. OBJECTIVE: We investigated whether intact milk proteins lower 24-h ambulatory blood pressure (AMBP) and other risk markers of CVD. DESIGN: The trial was a double-blinded, randomized, 3-way-crossover, controlled intervention study...
October 26, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27752755/methylglyoxal-treatment-in-lactating-mothers-leads-to-type-2-diabetes-phenotype-in-male-rat-offspring-at-adulthood
#6
Flávio Andrade Francisco, Luiz Felipe Barella, Sandra da Silva Silveira, Lucas Paulo Jacinto Saavedra, Kelly Valério Prates, Vander Silva Alves, Claudinéia Conationi da Silva Franco, Rosiane Aparecida Miranda, Tatiane Aparecida Ribeiro, Laize Peron Tófolo, Ananda Malta, Elaine Vieira, Kesia Palma-Rigo, Audrei Pavanello, Isabela Peixoto Martins, Veridiana Mota Moreira, Júlio Cezar de Oliveira, Paulo Cezar de Freitas Mathias, Rodrigo Mello Gomes
PURPOSE: Environmental and nutritional disorders during perinatal period cause metabolic dysfunction in the progeny and impair human health. Advanced glycation end products (AGEs) are primarily produced during metabolism of excess blood glucose, which is observed in diabetes. Methylglyoxal (MG) is a precursor for the generation of endogenous AGEs, which disturbs the metabolism. This work aimed to investigate whether the maternal MG treatment during lactation programs the progeny to metabolic dysfunction later in life...
October 17, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27733770/effects-of-milk-proteins-on-blood-pressure-a-meta-analysis-of-randomized-control-trials
#7
Khemayanto Hidayat, Hong-Zhen Du, Jing Yang, Guo-Chong Chen, Zheng Zhang, Zeng-Ning Li, Li-Qiang Qin
Certain foods or their components are widely used in the prevention and/or management of cardiovascular disease. Milk proteins have been suggested to have hypotensive properties. A number of clinical trials have been carried out to evaluate the effect of milk proteins from whole foods and supplements on blood pressure (BP). However, the effect of milk proteins on BP is not well understood. Therefore, we conducted a meta-analysis of randomized control trials to provide insight into and robust evidence concerning the overall impact of milk proteins on BP...
October 13, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/27668650/adropin-physiological-and-pathophysiological-role
#8
Natalia Marczuk, Elżbieta Cecerska-Heryć, Anna Jesionowska, Barbara Dołęgowska
Adropin is a peptide hormone that was discovered in 2008 by Kumar et al. This protein consists of 76 amino acids, and it was originally described as a secreted peptide, with residues 1-33 encoding a secretory signal peptide sequence. The amino acid sequence of this protein in humans, mice and rats is identical. While our knowledge of the exact physiological roles of this poorly understood peptide continues to evolve, recent data suggest a role in energy homeostasis and the control of glucose and fatty acid metabolism...
2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27652072/strawberry-milk-like-blood-in-a-subject-with-diabetic-lipemia-dramatic-change-to-transparent-color-after-insulin-therapy
#9
Atsushi Obata, Shinji Kamei, Seizo Okauchi, Tomohiko Kimura, Hidenori Hirukawa, Akihito Tanabe, Tomoe Kinoshita, Kenji Kohara, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
INTRODUCTION: It is known that chylomicronemia is caused by several pathologies and is classified as primary and secondary chylomicronemia. Since hypertriglycemia is associated with an increased risk of cardiovascular disease and severe pancreatitis, it is very important to make a proper diagnosis of the cause of hypertriglycemia. CASE DESCRIPTION: We herein present the case of a 40-year-old male who developed severe hypertriglycemia accompanied with acute exacerbation of type 2 diabetes mellitus...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27636835/systematic-evaluation-on-the-effectiveness-of-conjugated-linoleic-acid-in-human-health
#10
Gitane Fuke, José Laerte Nornberg
The term CLA (conjugated linoleic acid) corresponds to a mixture of positional and geometric isomers of linoleic acid. Two of these isomers (9c, 11t and 10t, 12c) have biological activity. The milk and dairy products are the most abundant source of conjugated linoleic acid, which refers to a group of positional and geometric isomers of CLA (CLA 18:2 cis-9, cis-12). The following research aims to approach aspects regarding the CLA, as well as its relationship with diseases. Conjugated linoleic acids have been studied for their beneficial effects in the prevention and treatment of many diseases, including obesity, cancer, diabetes, and cardiovascular diseases...
January 2, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/27624874/associations-of-the-mcm6-rs3754686-proxy-for-milk-intake-in-mediterranean-and-american-populations-with-cardiovascular-biomarkers-disease-and-mortality-mendelian-randomization
#11
Caren E Smith, Oscar Coltell, Jose V Sorlí, Ramón Estruch, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Montserrat Fitó, Fernando Arós, Hassan S Dashti, Chao Q Lai, Leticia Miró, Lluís Serra-Majem, Enrique Gómez-Gracia, Miquel Fiol, Emilio Ros, Stella Aslibekyan, Bertha Hidalgo, Marian L Neuhouser, Chongzhi Di, Katherine L Tucker, Donna K Arnett, José M Ordovás, Dolores Corella
Controversy persists on the association between dairy products, especially milk, and cardiovascular diseases (CVD). Genetic proxies may improve dairy intake estimations, and clarify diet-disease relationships through Mendelian randomization. We meta-analytically (n ≤ 20,089) evaluated associations between a lactase persistence (LP) SNP, the minichromosome maintenance complex component 6 (MCM6)-rs3754686C>T (nonpersistence>persistence), dairy intake, and CVD biomarkers in American (Hispanics, African-American and Whites) and Mediterranean populations...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27603889/-dyslipidemia-and-hypertension
#12
Ulices Alvirde-García
Most of the recent observational studies have failed to find an association between dairy intake and increased risk of cardiovascular disease, coronary heart disease and stroke, regardless of milk fat content. The purpose of this review is to examine the published research on the relationship between milk products containing milk fat and cardiovascular health. Despite their saturated fat content, there is no clear evidence of an association between dairy intake and an increased risk of cardiovascular disease (CVD)...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27603886/-elder
#13
Pedro Arroyo, Luis Miguel Gutiérrez-Robledo
The aim of this review is to present scientific evidence on the biological, dietary, cultural and economic advantages of cow´s milk and dairy products intake in adults, with emphasis on the elderly. The role of milk and dairy products as part of the regular diet, as well as their contribution to a healthy diet for the aged population is described. The updated scientific references on the importance of milk and dairy products on the dietary management of the most prevalent diseases of the eldery -among these energy-protein malnutrition, sarcopenia, obesity, sarcopenic obesity, osteoporosis, diabetes and cardiovascular diseases- are presented...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27579006/milk-derived-bioactive-peptides-and-their-impact-on-human-health-a-review
#14
REVIEW
D P Mohanty, S Mohapatra, S Misra, P S Sahu
Milk-derived bioactive peptides have been identified as potential ingredients of health-promoting functional foods. These bioactive peptides are targeted at diet-related chronic diseases especially the non-communicable diseases viz., obesity, cardiovascular diseases and diabetes. Peptides derived from the milk of cow, goat, sheep, buffalo and camel exert multifunctional properties, including anti-microbial, immune modulatory, anti-oxidant, inhibitory effect on enzymes, anti-thrombotic, and antagonistic activities against various toxic agents...
September 2016: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/27572703/potential-role-of-bioactive-peptides-in-prevention-and-treatment-of-chronic-diseases-a-narrative-review
#15
Arrigo Fg Cicero, Federica Fogacci, Alessandro Colletti
In the last years, a growing interest has been directed to bioactive peptides of animal and plant origin: in particular, researchers focused their attention on their mechanisms of action and their potential role in the prevention and treatment of cancer, cardiovascular and infective diseases. A search strategy was developed to identify studies in PubMed (January 1980 to May 2016); in particular, the authors selected papers reporting comprehensive reviews or meta-analyses, or studies in vitro and in vivo and clinical trials on bioactive peptides with an action on cardiovascular diseases, immunity, cancer or with an antioxidant, anti-inflammatory, antimicrobial effects...
August 29, 2016: British Journal of Pharmacology
https://www.readbyqxmd.com/read/27566575/peptidome-analysis-of-human-milk-from-women-delivering-macrosomic-fetuses-reveals-multiple-means-of-protection-for-infants
#16
Xianwei Cui, Yun Li, Lei Yang, Lianghui You, Xing Wang, Chunmei Shi, Chenbo Ji, Xirong Guo
Breastfeeding is associated with a lower incidence of obesity, diabetes, and cardiovascular disease later in life. While macrosomic infants have a higher risk of developing obesity and other metabolic disorders. Breast milk may contain special nutrients to meet the different growth needs of different infants. Whether mothers make breast milk different to meet the requirement of macrosomic infants is still unknown. Here, we conducted a comparison between mothers delivering macrosomic and non-macrosomic infants in colostrum endogenous peptides...
August 23, 2016: Oncotarget
https://www.readbyqxmd.com/read/27545902/nutritional-interventions-for-survivors-of-childhood-cancer
#17
REVIEW
Jennifer E Cohen, Claire E Wakefield, Richard J Cohn
BACKGROUND: Childhood cancer survivors are at a higher risk of developing health conditions such as osteoporosis, and cardiovascular disease than their peers. Health-promoting behaviour, such as consuming a healthy diet, could lessen the impact of these chronic issues, yet the prevalence rate of health-protecting behaviour amongst survivors of childhood cancer is similar to that of the general population. Targeted nutritional interventions may prevent or reduce the incidence of these chronic diseases...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27531185/from-trash-to-treasure-the-untapped-potential-of-endothelial-microparticles-in-neurovascular-diseases
#18
J Winny Yun, Adam Xiao, Ikuo Tsunoda, Alireza Minagar, J Steven Alexander
Discovered in 1947, microparticles (MP) represent a group of sub-micron cell-derived particles isolated by high speed centrifugation. Once regarded as cellular 'trash', in the past decade MP have gained tremendous attention in both basic sciences and medical research both as biomarkers and mediators of infection, injury and response to therapy. Because MP bear cell surface markers derived from parent cells, accumulate in extracellular fluids (plasma, serum, milk, urine, cerebrospinal fluid) MP based tests are being developed commercially as important components in 'liquid biopsy' approaches, providing valuable readouts in cardiovascular disease and cancer, as well as stroke, Alzheimer's disease and Multiple Sclerosis...
August 12, 2016: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/27514147/-the-role-of-mother-s-milk-and-breast-feeding-medical-problems-during-the-lactation-period-lactobacilus-fermentum-a-new-approach-towards-the-prevention-and-the-treatment-of-acute-and-subacute-mastitis
#19
B Popova, D Mitev, A Nikolov
Breast feeding provides a lot of short and long-term benefits for the mother and the baby. It prevents the baby of gastrointestinal, urinary and respiratory infections, atopical conditions and assures long-term protection of cardiovascular and metabolic diseases. The breast feeding decreases the risk for the mother of ovary and breast carcinoma and creates a positive emotional bond between the mother and the baby Mother's milk is a species specific; its content is relatively stable regardless of mother's age race, way and place of living...
2016: Akusherstvo i Ginekologii︠a︡
https://www.readbyqxmd.com/read/27502763/human-milk-and-breastfeeding-an-intervention-to-mitigate-toxic-stress
#20
Sunny G Hallowell, Elizabeth B Froh, Diane L Spatz
The American Academy of Nursing has identified toxic stress in childhood as a health policy concern of high priority. Adult diseases (e.g., obesity, diabetes, hypertension and cardiovascular disease) should be viewed as developmental disorders that begin early in life that could be reduced with the alleviation of toxic stress in childhood. The provision of human milk/breastfeeding is an evidence-based intervention that may hold the greatest potential to mitigate the effects of toxic stress from the moment of birth...
July 14, 2016: Nursing Outlook
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