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milk and cancer

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https://www.readbyqxmd.com/read/28326003/effects-of-organic-food-consumption-on-human-health-the-jury-is-still-out
#1
Marcin Barański, Leonidas Rempelos, Per Ole Iversen, Carlo Leifert
The most recent systematic literature reviews and meta-analyses have indicated significant and nutritionally-relevant composition differences between organic and conventional foods. This included higher antioxidant, but lower cadmium and pesticide levels in organic crops, and higher omega-3 fatty acids concentrations in organic meat and dairy products. Also, results from a small number of human cohort studies indicate that there are positive associations between organic food consumption and reduced risk/incidence of certain acute diseases (e...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28288429/human-health-risk-assessment-of-ddts-and-hchs-through-dietary-exposure-in-nanjing-china
#2
Qianqian Zhang, Zhonghuan Xia, Minmin Wu, Liping Wang, Hao Yang
In a market based study in Nanjing, a typical southeast city in China, the most common consumed 23 kinds of foods from eleven different categories (vegetable, fruit, fish, pork, livestock meat, chicken, egg, milk, oil, rice and flour) were sampled in November 2015. The concentrations of DDTs and HCHs in foods were analyzed using gas chromatography with mass spectrometer detector. The residual amounts of DDTs and HCHs in foods were 0.95-3.53 ng g(-1) and 0.32-1.96 ng g(-1), respectively. The highest residual of ∑10OCPs was 4...
March 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/28279179/the-effect-of-bowel-preparation-regime-on-interfraction-rectal-filling-variation-during-image-guided-radiotherapy-for-prostate-cancer
#3
Ali Hosni, Tara Rosewall, Timothy Craig, Vickie Kong, Andrew Bayley, Alejandro Berlin, Robert Bristow, Charles Catton, Padraig Warde, Peter Chung
BACKGROUND: This study aimed to investigate the tolerability and impact of milk of magnesia (MoM) on interfraction rectal filling during prostate cancer radiotherapy. METHODS: Two groups were retrospectively identified, each consisting of 40 patients with prostate cancer treated with radiotherapy to prostate+/-seminal vesicles, with daily image-guidance in 78Gy/39fractions/8 weeks. The first-group followed anti-flatulence diet with MoM started 3-days prior to planning-CT and continued during radiotherapy, while the second-group followed the same anti-flatulence diet only...
March 9, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28278079/breast-carcinoma-associated-with-prolactinoma-a-case-report
#4
Yurong Zheng, Wenju Mo, Yang Yu, Dehong Zou, Xiangming He, Xianghou Xia, Jiejie Hu
We report a 28-year-old woman who presented with a 6-year history of milk-like discharge from both of her nipples and was diagnosed with prolactinoma based on computed tomography (CT) findings and serum prolactin level. Further breast examination revealed a mass located in the upper outer region of the left breast. She underwent subtotal pituitary tumor resection. Thereafter, modified radical mastectomy was performed for left breast cancer. Twelve years after treatment, prolactinoma recurrence was detected, and bromocriptine therapy was administered...
February 17, 2017: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/28243404/effect-of-persian-medicine-remedy-on-chemotherapy-induced-nausea-and-vomiting-in-breast-cancer-a-double-blind-randomized-crossover-clinical-trial
#5
Mohammad Nazari, Ali Taghizadeh, Mojtaba Mousavi Bazzaz, Hassan Rakhshandeh, Sadegh Shokri
BACKGROUND: Chemotherapy induced nausea and vomiting (CINV) is a side effect, and has negative effect on quality of life and continuation of chemotherapy. Despite new regimen and drugs, the problems still remain and standard guidelines, effective treatment and supportive care for refractory CINV are still not yet established. Persian medicine, the old Iranian medical school, offer Persumac (prepared from Rhus Coriaria and Bunium Persicum Boiss). OBJECTIVE: The specific objectives were to assess the effect of Persumac on the number and severity of nausea and vomiting in refractory CINV in acute and delayed phase...
January 2017: Electronic Physician
https://www.readbyqxmd.com/read/28240891/approach-for-pesticide-residue-analysis-for-metabolite-prothioconazole-desthio-in-animal-origin-food
#6
Hui Liu, Guojun Yao, Xueke Liu, Chang Liu, Jing Zhan, Donghui Liu, Peng Wang, Zhiqiang Zhou
Food safety problems such as damage to immune, nervous, and endocrine systems leading to cancer and malformations have received increasing attention. To achieve the maximum residue limits, the most discussed method of high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) is widely used with a advantage of high precision and resolution. Prothioconazole is a broad-spectrum thiocarbamate fungicide. It can rapidly metabolize to prothioconazole-desthio in different matrixes. Rapid and effective methods for the determination of prothioconazole-desthio in five kinds of different animal food were developed...
March 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28236708/comparative-study-on-the-occurrence-of-polycyclic-aromatic-hydrocarbons-in-breast-milk-and-infant-formula-and-risk-assessment
#7
Serena Santonicola, Alessandra De Felice, Luigi Cobellis, Nicola Passariello, Angela Peluso, Nicoletta Murru, Maria Carmela Ferrante, Raffaelina Mercogliano
The study compared the polycyclic aromatic hydrocarbons (PAH) profile of human milk collected from Italian mothers and different brands of infant formula available on Italian market. Levels of 14 PAHs most frequently occurred in food, PAH markers listed by Commission Regulation (EC) No. 1881/2006, and carcinogenic PAHs classified by the International Agency for Research on Cancer, were determined by high-pressure liquid chromatography with fluorescence detector. The average concentrations of total PAHs were 114...
May 2017: Chemosphere
https://www.readbyqxmd.com/read/28229968/cytotoxic-and-toxicogenomic-effects-of-silibinin-in-bladder-cancer-cells-with-different-tp53-status
#8
Daiane Teixeira DE Oliveira, Andre Luiz Ventura Savio, Joao Paulo DE Castro Marcondes, Tatiane Martins Barros, Ludmila Correia Barbosa, Daisy Maria Favero Salvadori, Glenda Nicioli DA Silva
Silibinin is a natural phenol found in the seeds of the milk thistle plant. Recent data have shown its effectiveness for preventing/treating bladder tumours. Therefore, in this study we investigated the cytotoxic and toxicogenetic activity of silibinin in bladder cancer cells with different TP53 statuses. Two bladder urothelial carcinoma cell lines were used: RT4 (wild-type TP53 gene) and T24 (mutated TP53 gene). Cell proliferation, clonogenic survival, apoptosis rates, genotoxicity and relative expression profile of FRAP/mTOR, FGFR3, AKT2 and DNMT1 genes and of miR100 and miR203 were evaluated...
March 2017: Journal of Biosciences
https://www.readbyqxmd.com/read/28229097/pediatric-hypovitaminosis-d-molecular-perspectives-and-clinical-implications
#9
Rafiu Ariganjoye
Vitamin D, a secosteroid, is essential for the development and maintenance of healthy bone in both the adult and pediatric populations. Low level of 25-hydroxy vitamin D (25-(OH)-D) is highly prevalent in children worldwide and has been linked to various adverse health outcomes including rickets, osteomalacia, osteomalacic myopathy, sarcopenia, and weakness, growth retardation, hypocalcemia, seizure and tetany, autism, cardiovascular diseases, diabetes mellitus, cancers (prostate, colon, breast), infectious diseases (viral, tuberculosis), and autoimmune diseases, such as multiple sclerosis and Hashimoto's thyroiditis...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28202351/exosomal-formulation-of-anthocyanidins-against-multiple-cancer-types
#10
Radha Munagala, Farrukh Aqil, Jeyaprakash Jeyabalan, Ashish K Agrawal, Ashley M Mudd, Al Hassan Kyakulaga, Inder P Singh, Manicka V Vadhanam, Ramesh C Gupta
Over the last two decades, berries and berry bioactives, particularly anthocyanins and their aglycones anthocyanidins (Anthos) have demonstrated excellent anti-oxidant, anti-proliferative, apoptotic and anti-inflammatory properties. However, their physicochemical and pharmacokinetic limitations such as, low permeability, and poor oral bioavailability are considered as unfavorable properties for development as drugs. Therefore there is a need to develop systems for efficient systemic delivery and robust bioavailability...
February 12, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28187509/dairy-intake-in-relation-to-prostate-cancer-survival
#11
Mary K Downer, Julie L Batista, Lorelei A Mucci, Meir J Stampfer, Mara Meyer Epstein, Niclas Håkansson, Alicja Wolk, Jan-Erik Johansson, Ove Andrén, Katja Fall, Sven-Olof Andersson
Dairy intake has been associated with increased risk of advanced prostate cancer. Two US cohort studies reported increased prostate cancer-specific mortality with increased high-fat milk intake. We examined whether dairy and related nutrient intake were associated with prostate cancer progression in a Swedish patient population with high dairy consumption. We prospectively followed 525 men with newly diagnosed prostate cancer (diagnosed 1989-1994). We identified and confirmed deaths through February 2011 (n = 222 prostate cancer-specific, n = 268 from other causes)...
May 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28179582/independent-and-joint-effects-of-tea-and-milk-consumption-on-oral-cancer-among-non-smokers-and-non-drinkers-a-case-control-study-in-china
#12
Fa Chen, Lingjun Yan, Lisong Lin, Fengqiong Liu, Yu Qiu, Fangping Liu, Jiangfeng Huang, Junfeng Wu, Lin Cai, Guoxi Cai, Kiyoshi Aoyagi, Baochang He
This study aims to evaluate the independent and joint effects of tea and milk consumption on oral cancer risk among non-smokers and non-drinkers (NS/ND). A hospital-based case-control study was performed in Fujian, China. 421 cases and frequency-matched 1398 controls were included without tobacco smoking and alcohol drinking habits. Unconditional logistic regression model was used to assess the relationship of tea and milk consumption with oral cancer risk. Tea and milk consumption were significantly associated with decreased risk of oral cancer, the adjusted odds ratios (aORs) were 0...
February 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28179486/serum-25-hydroxyvitamin-d-has-a-modest-positive-association-with-leukocyte-telomere-length-in-middle-aged-us-adults
#13
Julia Beilfuss, Carlos A Camargo, Elena Kamycheva
Background: Vitamin D deficiency has been linked to all-cause mortality and cancer. However, the biological plausibility of these associations is not well established. Leukocyte telomere length (LTL) shortening is associated with aging and is a hallmark of genomic instability and carcinogenesis.Objective: We aimed to investigate the association between serum 25-hydroxyvitamin D [25(OH)D] concentrations and LTL in the general US population.Methods: We analyzed data from the US NHANES 2001-2002. The study population comprised 1542 younger adults (aged 20-39 y), 1336 middle-aged adults (aged 40-59 y), and 1382 older adults (aged ≥60 y)...
February 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28170295/after-chemotherapy-treatment-for-maternal-cancer-during-pregnancy-is-breastfeeding-possible
#14
Stephen Stopenski, Anum Aslam, Xinmin Zhang, Elyce Cardonick
OBJECTIVE: To report breastfeeding complaints of women diagnosed with cancer during pregnancy and correlate success with characteristics of their treatment. MATERIALS AND METHODS: This is a prospective cohort study of women diagnosed with cancer during pregnancy who attempted breastfeeding. We surveyed participants about breast engorgement, milk let down, and consistent breast milk production through mailed questionnaires. Treatment details, including the type and number of chemotherapy cycles given during pregnancy and antepartum or postpartum depression, were collected...
March 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28169560/bovine-lactoferrin-and-lactoferricin-exert-antitumor-activities-on-human-colorectal-cancer-cells-ht-29-by-activating-various-signaling-pathways
#15
Rulan Jiang, Bo Lönnerdal
Lactoferrin (Lf) is an iron-binding glycoprotein that is present at high concentrations in milk. Bovine lactoferricin (LfcinB) is a peptide fragment generated by pepsin proteolysis of bovine lactoferrin (bLf). LfcinB consists of amino acid residues 17-41 proximal to the N-terminus of bLf and a disulfide bond between residues 19 and 36, forming a loop. Both bLf and LfcinB have been demonstrated to have antitumor activities. Colorectal cancer is the second most common cause of cancer death in developed countries...
February 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28137608/silymarin-protects-against-acrylamide-induced-neurotoxicity-via-nrf2-signalling-in-pc12-cells
#16
Liang Li, Hong-Yang Sun, Wei Liu, Hong-Yu Zhao, Mei-Li Shao
Silymarin (SM) is a well-known antioxidant, anti-inflammatory and anti-cancer compound extracted from the milk thistle. Here, we investigated the protective effect of SM against acrylamide (AA)-induced neurotoxicity, mainly caused by oxidative stress, via activation of the nuclear transcription factor E2-related factor 2 (Nrf2) signalling pathway in PC12 cells. The MTT reduction assay was used to measure cell viability in various drug-treated groups and demonstrated that SM could increase cell viability in AA-treated PC12 cells...
January 27, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28137239/targeted-theranostics-against-solid-cancer-using-metal-bond-milk-protein-and-aptamers
#17
Suman Chaudhary, Rupinder Kaur Kanwar, Jagat Rakesh Kanwar
Targeted therapeutics is a new generation therapy that can increase the efficacy of chemotherapeutic drugs, by facilitating site-specific delivery with minimum off-target effects. Amongst the targeted therapy, nucleic-acid based aptamers are increasingly gaining interest due to their small size, long shelf-life and ease in synthesis. Further, lactoferrin, a milk protein belonging to the transferrin family is now an established multi-functional iron-binding protein. Its applicability as an immunomodulator, antimicrobial and an anti-cancer agent has made this protein highly valuable...
January 30, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/28134423/tobacco-chewing-and-risk-of-gastric-cancer-a-case-control-study-in-yemen
#18
F A Al-Qadasi, S A Shah, H F Ghazi
This study aimed to assess the risk factors for gastric cancer in Yemen. A hospital-based case-control study of 70 cases and 140 controls was carried out in Sana'a city between May and October 2014. A structured questionnaire was used to collect information through direct interview. Living in rural areas, tobacco chewing and drinking untreated water were significant risk factors for gastric cancer. Frequent consumption of chicken, cheese, milk, starchy vegetables, cucumber, carrots, leeks, sweet pepper, fruit drinks, legumes and olive oil were associated significantly with decreased risk of gastric cancer...
January 23, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/28111361/tracing-cellular-origin-of-human-exosomes-using-multiplex-proximity-extension-assay
#19
Pia Larssen, Lotta Wik, Paulo Czarnewski, Maria Eldh, Liza Lof, Goran Ronquist, Louise Dubois, Eva Freyhult, Caroline Gallant, Johan Oelrich, Anders Larsson, Gunnar Ronquist, Eduardo Villablanca, Ulf Landegren, Susanne Gabrielsson, Masood Kamali-Moghaddam
Extracellular vesicles (EVs) are membrane-coated objects such as exosomes and microvesicles, released by many cell-types. Their presence in body fluids and the variable surface composition and content render them attractive potential biomarkers. The ability to determine their cellular origin could greatly move the field forward. We used multiplex proximity extension assays (PEA) to identify with high specificity and sensitivity the protein profiles of exosomes of different origins, including seven cell lines and two different body fluids...
January 22, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28111002/more-surprises-in-the-global-greenhouse-human-health-impacts-from-recent-toxic-marine-aerosol-formations-due-to-centennial-alterations-of-world-wide-coastal-food-webs
#20
REVIEW
J J Walsh, J M Lenes, R H Weisberg, L Zheng, C Hu, K A Fanning, R Snyder, J Smith
Reductions of zooplankton biomasses and grazing pressures were observed during overfishing-induced trophic cascades and concurrent oil spills at global scales. Recent phytoplankton increments followed, once Fe-, P-, and N-nutrient limitations of commensal diazotrophs and dinoflagellates were also eliminated by respective human desertification, deforestation, and eutrophication during climate changes. Si-limitation of diatoms instead ensued during these last anthropogenic perturbations of agricultural effluents and sewage loadings...
January 19, 2017: Marine Pollution Bulletin
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