Rebecca A Abelman, Jessica Fitzpatrick, Katerina L Byanova, Josephine Zawedde, Ingvar Sanyu, Patrick Byanyima, Emmanuel Musisi, Jenny Hsieh, Michelle Zhang, Jake Branchini, Abdul Sessolo, Peter W Hunt, Rejani Lalitha, J Lucian Davis, Kristina Crothers, William Worodria, Laurence Huang
BACKGROUND: Preserved ratio impaired spirometry (PRISm), defined as a normal ratio of forced expiratory volume in 1 second (FEV1 ) to forced vital capacity (≥0.70) with low FEV1 (<80% predicted), has been associated with increased mortality in the general population. Female sex has been associated with increased odds of PRISm in people without HIV. People with HIV (PWH) are at increased risk for lung function abnormalities, but whether HIV modifies the effect of sex on PRISm development is largely unknown...
March 2024: Open Forum Infectious Diseases