Read by QxMD icon Read

tetracyclin in pregnancy

Robert D Kirkcaldy, Alesia Harvey, John R Papp, Carlos Del Rio, Olusegun O Soge, King K Holmes, Edward W Hook, Grace Kubin, Stefan Riedel, Jonathan Zenilman, Kevin Pettus, Tremeka Sanders, Samera Sharpe, Elizabeth Torrone
PROBLEM/CONDITION: Gonorrhea is the second most commonly reported notifiable disease in the United States; 350,062 gonorrhea cases were reported in 2014. Sexually transmitted infections caused by Neisseria gonorrhoeae are a cause of pelvic inflammatory disease in women, which can lead to serious reproductive complications including tubal infertility, ectopic pregnancy, and chronic pelvic pain. Prevention of sequelae and of transmission to sexual partners relies largely on prompt detection and effective antimicrobial treatment...
2016: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
Ewelina Bogumiła Zuba, Wojciech Francuzik, Przemysław Malicki, Agnieszka Osmola-Mańkowska, Dorota Jenerowicz
Dear Editor, Ultraviolet (UV) radiation is a well-known physical hazard responsible for photoaging, photoallergic, and phototoxic reactions as well as carcinogenesis, including life-threatening melanomas (1,2). Overexposure to both natural and artificial UV radiation is a public health concern. 30% of cancers diagnosed worldwide are skin cancers. Approximately three million non-melanoma skin cancers and 132 000 new cases of melanomas are diagnosed globally each year (3). Sunburns, especially in childhood, are a very important risk factor for melanomas...
April 2016: Acta Dermatovenerologica Croatica: ADC
Sima Azizmohammadi, Susan Azizmohammadi
BACKGROUND: Mycoplasma hominis and Ureaplasma urealyticum bring with them an increased risk of pregnancy complications, such as premature membrane rupture, vaginitis and preterm birth. OBJECTIVES: The present investigation was carried out to study the prevalence of M. hominis and U. urealyticum in pregnant women and to study their resistance against commonly used antibiotics. MATERIALS AND METHODS: Three hundred and fifty high vaginal swabs were taken from pregnant women...
December 2015: Iranian Red Crescent Medical Journal
Ruby Cross, Clare Ling, Nicholas P J Day, Rose McGready, Daniel H Paris
INTRODUCTION: Doxycycline is highly effective, inexpensive with a broad therapeutic spectrum and exceptional bioavailability. However these benefits have been overshadowed by its classification alongside the tetracyclines - class D drugs, contraindicated in pregnancy and in children under 8 years of age. Doxycycline-treatable diseases are emerging as leading causes of undifferentiated febrile illness in Southeast Asia. For example scrub typhus and murine typhus have an unusually severe impact on pregnancy outcomes, and current mortality rates for scrub typhus reach 12-13% in India and Thailand...
2016: Expert Opinion on Drug Safety
Y Yakimova
BACKGROUND: Patients decide to take antibiotics themselves in 21% of cases of acute respiratory viral infections, influenza and acute respiratory infections [1]. The main factor of drug purchase at a pharmacy is pharmacist's recommendation. In 14% of cases of purchase of antibiotics, patients describe the symptoms and do not name a specific drug. This provides opportunity for drug selection at a pharmacy [2]. In these circumstances the role of pharmacists in ensuring the rational use of antimicrobial agents increases significantly...
2015: International Journal of Risk & Safety in Medicine
P Brandon Bookstaver, Christopher M Bland, Brooke Griffin, Kayla R Stover, Lea S Eiland, Milena McLaughlin
During pregnancy, untreated sexually transmitted or urinary tract infections are associated with significant morbidity, including low birth weight, preterm birth, and spontaneous abortion. Approximately one in four women will be prescribed an antibiotic during pregnancy, accounting for nearly 80% of prescription medications in pregnant women. Antibiotic exposures during pregnancy have been associated with both short-term (e.g., congenital abnormalities) and long-term effects (e.g., changes in gut microbiome, asthma, atopic dermatitis) in the newborn...
November 2015: Pharmacotherapy
(no author information available yet)
Gonorrhea is the second most commonly reported bacterial sexually transmitted disease in the United States, with an estimated 820,000 new Neisseria gonorrhoeae infections occurring each year. Antimicrobial resistance limits treatment success, heightens the risk of complications, and may facilitate the transmission of sexually transmitted infections. Neisseria gonorrhoeae has developed resistance to the sulfonamides, the tetracyclines, and penicillin. Dual therapy with ceftriaxone and azithromycin remains the only recommended first-line regimen for the treatment of gonorrhea in the United States...
November 2015: Obstetrics and Gynecology
(no author information available yet)
Gonorrhea is the second most commonly reported bacterial sexually transmitted disease in the United States, with an estimated 820,000 new Neisseria gonorrhoeae infections occurring each year. Antimicrobial resistance limits treatment success, heightens the risk of complications, and may facilitate the transmission of sexually transmitted infections. Neisseria gonorrhoeae has developed resistance to the sulfonamides, the tetracyclines, and penicillin. Dual therapy with ceftriaxone and azithromycin remains the only recommended first-line regimen for the treatment of gonorrhea in the United States...
November 2015: Obstetrics and Gynecology
Yichen Lee, Chuchieh Chen, Dachen Chu, Mingchung Ko
RATIONALE, AIMS AND OBJECTIVES: Inappropriate antibiotic prescriptions during pregnancy may adversely affect the fetus. There were few studies on factors associated with antibiotic prescriptions potentially harmful to the fetus. METHODS: This was a population-based cross-sectional study using data from National Health Insurance Research Database. We calculated the frequency of antibiotic prescription according to the status of pregnancy, type of infections, characteristics of patients, doctors and medical institutions...
April 2016: Journal of Evaluation in Clinical Practice
Shahrzad Hadavand, Fatemeh Ghafoorimehr, Leila Rajabi, Ali Davati, Nafiseh Zafarghandi
BACKGROUND & OBJECTIVES: One of the important infectious factors in pregnant mothers and newborns is Group B Streptococcus (GBS). There is no perfect report about prevalence of GBS in Iran and in the case of preterm rupture of amniotic membrane or preterm labor all patients are treated by antibiotics without culture so this has led to adverse taking antibiotics and drug resistance. The present study is intended to determine the frequency of colonization of GBS in the pregnant mother (35-37 weeks), referred to medical centers of Shahed University...
2015: Iranian Journal of Pathology
Natalie C Momen, Jørn Olsen, Mika Gissler, Helle Kieler, Bengt Haglund, Jiong Li
BACKGROUND: Up to one-third of women receive prescriptions for systemic antibacterial medications during pregnancy. This paper looks at the association between maternal use of systemic antibacterial medications during pregnancy and childhood cancer risk in the offspring using the prospective data on medication. METHODS: A population-based follow-up study was carried out using Danish and Swedish register data. Exposure was maternal redemption of a prescription for a systemic antibacterial in the 3 months prior to pregnancy and during pregnancy (exposure window) documented in the national prescription registers, and offspring were followed up from birth to a cancer diagnosis, death, emigration, day before 15th birthday or end of follow-up, whichever came first...
August 2015: Pharmacoepidemiology and Drug Safety
Wondemagegn Mulu, Mulat Yimer, Yohannes Zenebe, Bayeh Abera
BACKGROUND: Bacterial vaginosis, candidal, trichomonal and Gonococcal vaginal infections are a major health problems associated with gynecologic complications and increase in replication, shedding and transmission of HIV and other STIs in women of reproductive age. The study aimed at determining the prevalence of common vaginal infections and antimicrobial susceptibility profiles of aerobic bacterial isolates in women of reproductive age, attending Felegehiwot referral Hospital. METHODS: A hospital based cross sectional study was conducted from May to November, 2013...
2015: BMC Women's Health
A R Melkumyan, T V Priputnevich, A S Ankirskaya, V V Murav'eva, L A Lubasovskaya
We analyzed sensitivity of 123 vaginal lactobacillus strains to antibacterial substances. All lactobacillus strains were sensitive to ampicillin, cefazolin, cefotaxime, and vancomycin, and insensitive to metronidazole, trimethoprim/sulfamethoxazole, and levofloxacin. Lactobacillus strains demonstrated different sensitivity to gentamycin, clindamycin, erythromycin, ciprofloxacin, and tetracycline. The phenomenon of preferential selective influence of antibacterial drugs on the composition of lactobacilli of the vaginal microbiota, in which some lactobacilli survive as part of the vaginal microbiota and have a selective advantage over other types of lactobacilli, should be taken into account during treatment of vaginal infections and dysbiosis...
April 2015: Bulletin of Experimental Biology and Medicine
P Kokkayil, B Dhawan
Ureaplasma species are the most prevalent genital Mycoplasma isolated from the urogenital tract of both men and women. Ureaplasma has 14 known serotypes and is divided into two biovars- Ureaplasma parvum and Ureaplasma urealyticum. The organism has several genes coding for surface proteins, the most important being the gene encoding the Multiple Banded Antigen (MBA). The C-terminal domain of MBA is antigenic and elicits a host antibody response. Other virulence factors include phospholipases A and C, IgA protease and urease...
April 2015: Indian Journal of Medical Microbiology
Reza Beigverdi, Fereshteh Jabalameli, Akbar Mirsalehian, Sedigheh Hantoushzadeh, Shahram Boroumandi, Morovat Taherikalani, Mohammad Emaneini
Forty-one Streptococcus agalactiae isolates collected from pregnant women at 35-37 weeks of gestation were analysed for their capsular types, antimicrobial resistance determinants, distribution of virulence factors and genetic relatedness using PCR and multiplex PCR. Capsular type III was predominant (65.8%), followed by capsular type II (14.6%), Ib (7.3%), and V(4.9%). All isolates were susceptible to penicillin, vancomycin, linezolid and quinupristin-dalfopristin. Resistance to tetracycline, erythromycin and clindamycin were found in 97...
December 2014: Acta Microbiologica et Immunologica Hungarica
Anne Karin Brigtsen, Lumnije Dedi, Kjetil K Melby, Mona Holberg-Petersen, Andreas Radtke, Randi Valsø Lyng, Lise Lima Andresen, Anne Flem Jacobsen, Drude Fugelseth, Andrew Whitelaw
Streptococcus agalactiae (GBS) is a leading cause of invasive neonatal infection. Serotyping of GBS is important in following epidemiological trends and vaccine development. Capsular serotyping of GBS by latex agglutination has been the predominant typing method, but more recently capsular genotyping has been introduced as an alternative method. The purpose of this study was to compare the relative performance of these methods in a contemporary population of pregnant women. We typed isolates from an unselected population of 426 colonized women at delivery using latex agglutination and a combination of four PCR methods...
January 2015: Journal of Microbiological Methods
N Eskandarian, Z Ismail, V Neela, A van Belkum, M N M Desa, S Amin Nordin
A total of 103 group B streptococci (GBS) including 22 invasive, 21 non-invasive, and 60 colonizing isolates were collected in a Malaysian hospital (June 2010-October 2011). Isolates were characterized by conventional and molecular serotyping and analyzed for scpB, lmb, hylB, cylE, bac, bca and rib gene content. Antimicrobial susceptibility to penicillins, macrolides, lincosamides, quinolones and tetracyclines was determined using disk diffusion and the MICs for penicillin were determined by E-test. Molecular serotyping for all eight serotypes (Ia, Ib, II-VII) was in full accordance with conventional serotyping...
March 2015: European Journal of Clinical Microbiology & Infectious Diseases
M L Sizonenko, G V Briukhin
The effect of chronic injury of hepatobiliary system of various genesis in females rats on the formation of spermatogenic epithelium in the testis of their newborn offspring was studied. The models of toxic (CCl4) and medicinal (tetracycline, paracetamol) liver injury were used. The state of the seminiferous epithelium was assessed on the serial histological sections of the testis with the use of the morphometric device. In experimental animals, a reduction of the diameter and the area of the seminiferous tubules (ST) was detected, associated with the decline of the total number of spermatogenic cells, spermatogonia of various generations, total number of spermatocytes and Sertoli cells...
2014: Morfologi︠a︡
Gerald Msukwa, Nkume Batumba, Mitchell Drucker, Lynette Menezes, Roshni Ranjit
CONTEXT: Neonatal conjunctivitis is associated with poor prenatal care worldwide. PURPOSE: Data on neonatal conjunctivitis is scarce in Malawi. This study describes risk factors associated with conjunctivitis in neonates born in a large tertiary care hospital in Blantyre, Malawi. MATERIALS AND METHODS: Medical records of a retrospective cohort of 231 neonates diagnosed with conjunctivitis from January 2006 to December 2009 at a large tertiary hospital in Malawi were reviewed...
July 2014: Middle East African Journal of Ophthalmology
Orhan Sahin, Eric R Burrough, Nada Pavlovic, Tim S Frana, Darin M Madson, Qijing Zhang
Although Campylobacter jejuni is a common cause of ruminant abortion with great economic impact, the organism has rarely been implicated in canine pregnancy loss, with only 2 documented cases to date. In the current report, 2 cases of perinatal death in adult female Bulldogs associated with C. jejuni infection of fetoplacental organs are described. Fetuses and placentas were received at the Iowa State University Veterinary Diagnostic Laboratory (Ames, Iowa) from 3 puppies that died soon after the birth (case 1) and from an aborted fetus (case 2)...
September 2014: Journal of Veterinary Diagnostic Investigation
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"