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https://www.readbyqxmd.com/read/29789706/short-segment-transverse-myelitis-lesions-in-a-cohort-of-latin-american-patients-with-neuromyelitis-optica-spectrum-disorders
#1
Edgar Carnero Contentti, Vanessa Daccach Marques, Ibis Soto de Castillo, Verónica Tkachuk, Amilton Antunes Barreira, Elizabeth Armas, Edson Chiganer, Camila de Aquino Cruz, José Luis Di Pace, Javier Pablo Hryb, Carolina Lavigne Moreira, Carmen Lessa, Omaira Molina, Mónica Perassolo, Arnoldo Soto, Alejandro Caride
STUDY DESIGN: Multicenter retrospective study. OBJECTIVES: The aim was to determine the frequency and magnetic resonance imaging (MRI) features of short-segment transverse myelitis (STM) in patients with neuromyelitis optica spectrum disorders (NMOSD) during a myelitis attack. SETTING: Latin American diagnostic centres (Neuroimmunology Unit). A multicenter study from Argentina, Brazil and Venezuela was performed. METHODS: Seventy-six patients with NMOSD were included...
May 22, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29788538/hepatitis-e-virus-in-south-america-the-current-scenario
#2
María Belén Pisano, Maribel Martínez Wassaf, Santiago Mirazo, Anabella Fantilli, Juan Arbiza, José Debes, Viviana E Ré
Hepatitis E virus (HEV) is one of the most frequent causes of acute viral hepatitis of enteric transmission worldwide. In South America the overall epidemiology has been little studied, and the burden of the disease remains largely unknown. A research of all scientific articles about HEV circulation in South America until November 2017 was carried out. Human seroprevalences of HEV varied according to the studied population: blood donors presented prevalence rates ranging from 1.8 to 9.8%, while reports from HIV-infected individuals, transplant recipients and patients on hemodialysis showed higher prevalence rates...
May 22, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29780019/parasitic-infections-in-individuals-travelling-to-america-and-precautionary-measures
#3
Mehmet Aykur, Muhammet Karakavuk, Ayşegül Ünver, Hande Dağcı
Over the past decade, the number of international travels has increased. Hence, the risk of transmission of parasitic diseases has also increased. One of the risk infections is malaria; Plasmodium vivax and P. falciparum species can be transmitted. The distribution of leishmaniasis cases has been reported from the south of USA to the north of Argentina. Approximately 57,000 cases of cutaneous and mucocutaneous leishmaniasis occur annually, and approximately 4000 visceral leishmaniasis cases are observed. It is reported that Chagas disease is endemic in 21 countries, and approximately 6 million people are affected every year...
March 2018: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29756184/determinants-of-co-2-emissions-in-the-mercosur-the-role-of-economic-growth-and-renewable-and-non-renewable-energy
#4
Emerson Santana de Souza, Fátima de Souza Freire, Josimar Pires
The main objective of this study was to analyze the impact of energy consumption (divided into renewable and non-renewable sources) and income on CO2 emissions within the environmental Kuznets curve (EKC) model for the Southern Common Market (MERCOSUR). To do so, the annual panel data collected during the 1990-2014 periods was used. The CO2 variable, representing carbon dioxide emissions in metric tons per capita, was used as a proxy for the emission of pollutants. The annual data were obtained from the World Bank (World Development Indicators)...
May 13, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29752682/new-perspectives-in-fire-management-in-south-american-savannas-the-importance-of-intercultural-governance
#5
Jayalaxshmi Mistry, Isabel Belloni Schmidt, Ludivine Eloy, Bibiana Bilbao
Wildfires continue to cause damage to property, livelihoods and environments around the world. Acknowledging that dealing with wildfires has to go beyond fire-fighting, governments in countries with fire-prone ecosystems have begun to recognize the multiple perspectives of landscape burning and the need to engage with local communities and their practices. In this perspective, we outline the experiences of Brazil and Venezuela, two countries where fire management has been highly contested, but where there have been recent advances in fire management approaches...
May 11, 2018: Ambio
https://www.readbyqxmd.com/read/29750799/population-specific-genetic-modification-of-huntington-s-disease-in-venezuela
#6
Michael J Chao, Kyung-Hee Kim, Jun Wan Shin, Diane Lucente, Vanessa C Wheeler, Hong Li, Jared C Roach, Leroy Hood, Nancy S Wexler, Laura B Jardim, Peter Holmans, Lesley Jones, Michael Orth, Seung Kwak, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Modifiers of Mendelian disorders can provide insights into disease mechanisms and guide therapeutic strategies. A recent genome-wide association (GWA) study discovered genetic modifiers of Huntington's disease (HD) onset in Europeans. Here, we performed whole genome sequencing and GWA analysis of a Venezuelan HD cluster whose families were crucial for the original mapping of the HD gene defect. The Venezuelan HD subjects develop motor symptoms earlier than their European counterparts, implying the potential for population-specific modifiers...
May 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29748634/gene-by-environment-interactions-that-disrupt-mitochondrial-homeostasis-cause-neurodegeneration-in-c-elegans-parkinson-s-models
#7
Hanna Kim, Rylee J Perentis, Guy A Caldwell, Kim A Caldwell
Parkinson's disease (PD) is a complex multifactorial disorder where environmental factors interact with genetic susceptibility. Accumulating evidence suggests that mitochondria have a central role in the progression of neurodegeneration in sporadic and/or genetic forms of PD. We previously reported that exposure to a secondary metabolite from the soil bacterium, Streptomyces venezuelae, results in age- and dose-dependent dopaminergic (DA) neurodegeneration in Caenorhabditis elegans and human SH-SY5Y neurons...
May 10, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29726390/the-my-child-matters-programme-effect-of-public-private-partnerships-on-paediatric-cancer-care-in-low-income-and-middle-income-countries
#8
REVIEW
Scott C Howard, Alia Zaidi, Xueyuan Cao, Olivier Weil, Pierre Bey, Catherine Patte, Angelica Samudio, Laurie Haddad, Catherine G Lam, Claude Moreira, Augusto Pereira, Mhamed Harif, Laila Hessissen, Salma Choudhury, Ligia Fu, Miguela A Caniza, Julius Lecciones, Fousseyni Traore, Raul C Ribeiro, Anne Gagnepain-Lacheteau
In low-income and middle-income countries, an excess in treatment failure for children with cancer usually results from misdiagnosis, inadequate access to treatment, death from toxicity, treatment abandonment, and relapse. The My Child Matters programme of the Sanofi Espoir Foundation has funded 55 paediatric cancer projects in low-income and middle-income countries over 10 years. We assessed the impact of the projects in these regions by using baseline assessments that were done in 2006. Based on these data, estimated 5-year survival in 2016 increased by a median of 5·1%, ranging from -1·5% in Venezuela to 17·5% in Ukraine...
May 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29720524/high-rate-of-infection-by-only-oncogenic-human-papillomavirus-in-amerindians
#9
Daniela Vargas-Robles, Magda Magris, Natalia Morales, Maurits N C de Koning, Iveth Rodríguez, Tahidid Nieves, Filipa Godoy-Vitorino, Gloria I Sánchez, Luis David Alcaraz, Larry J Forney, María-Eglée Pérez, Luis García-Briceño, Leen-Jan van Doorn, María Gloria Domínguez-Bello
Human papillomavirus (HPV), an etiological agent of cervical cancer (CC), has infected humans since ancient times. Amerindians are the furthest migrants out of Africa, and they reached the Americas more than 14,000 years ago. Some groups still remain isolated, and some migrate to towns, forming a gradient spanning urbanization. We hypothesized that, by virtue of their history, lifestyle, and isolation from the global society, remote Amerindian women have lower HPV diversity than do urban women (Amerindian or mestizo)...
June 27, 2018: MSphere
https://www.readbyqxmd.com/read/29719979/effect-sizes-and-cut-off-points-a-meta-analytical-review-of-burnout-in-latin-american-countries
#10
Jose García-Arroyo, Amparo Osca Segovia
Burnout is a highly prevalent globalized health issue that causes significant physical and psychological health problems. In Latin America research on this topic has increased in recent years, however there are no studies comparing results across countries, nor normative reference cut-offs. The present meta-analysis examines the intensity of burnout (emotional exhaustion, cynicism and personal accomplishment) in 58 adult nonclinical samples from 8 countries (Argentina, Brazil, Chile, Colombia, Ecuador, Mexico, Peru and Venezuela)...
May 2, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29718127/madariaga-virus-identification-of-a-lineage-iii-strain-in-a-venezuelan-child-with-acute-undifferentiated-febrile-illness-in-the-setting-of-a-possible-equine-epizootic
#11
Gabriela M Blohm, John A Lednicky, Sarah K White, Carla N Mavian, Marilianna C Márquez, Kellyh P González-García, Marco Salemi, J Glenn Morris, Alberto E Paniz-Mondolfi
We report identification of Madariaga virus (MADV) in plasma and urine samples from a child with acute undifferentiated febrile illness in Venezuela. Our data document the occurrence of milder MADV infections (ie, without encephalitis), with a symptom complex that resembles that seen with other arboviral infections, including dengue and zika.
April 27, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29713556/relapsing-malaria-a-case-report-of-primaquine-resistance
#12
Christopher Dijanic, Jillian Nickerson, Sunita Shakya, Amanda Dijanic, Marilyn Fabbri
Primaquine (an 8-aminoquinoline malarial therapy) is the only FDA-approved therapy to treat the hypnozoite stage of P. vivax . We think of relapse occurring because of parasitic resistance or poor compliance secondary to drug toxicities. However, in patients with repeated treatment failure, we must consider CYP-450 mutations affecting drug metabolism as an important cause of relapse. A 47-year-old man who travelled to a jungle in Venezuela was diagnosed with P. falciparum and P. vivax in July 2015. He was treated with seven rounds of primaquine-based therapy in the following year, all resulted in relapse without further exposure to endemic areas...
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29700425/isolation-of-a-jadomycin-incorporating-l-ornithine-analysis-of-antimicrobial-activity-and-jadomycin-reactive-oxygen-species-ros-generation-in-mda-mb-231-breast-cancer-cells
#13
Stephanie M Forget, Andrew W Robertson, Steven R Hall, Jeanna M MacLeod, David P Overy, Russell G Kerr, Kerry B Goralski, David L Jakeman
Herein, we report the characterization and antimicrobial activity of a previously unreported jadomycin (1) obtained from a culture of S. venezuelae ISP5230 with L-ornithine (Orn). 1 arises from the rearrangement of a putative five-membered ring containing jadomycin incorporating Orn, whereby intramolecular attack of the E-ring carbonyl from the δ-NH2 group of the Orn side chain results in collapse of the oxazolone ring and formation of a stable six-membered lactam. This rearrangement produces a jadomycin with a 3a hemiaminal position that is susceptible to solvolysis...
April 26, 2018: Journal of Antibiotics
https://www.readbyqxmd.com/read/29694596/integrality-in-brazil-and-venezuela-similarities-and-complementarities
#14
Carla Targino Bruno Dos Santos, Ione Silva Barros, Anne Caroline Coelho Leal Árias Amorim, Dais Gonçalves Rocha, Ana Valéria Machado Mendonça, Maria Fátima de Sousa
This study aims to compare Primary Health Care (PHC) in Brazil and Venezuela, considering its characteristics as to integrality. It has a qualitative approach, using documental analysis, semi-structured interviews with key informants and field diary notes. We observed the three realms of integrality inherent to the health work process: comprehensive and holistic care, the individual viewed as a complex being with multiple needs, requiring the connection of various health knowledge; continuity of care in institutional micro-policy with interprofessional articulation, in order to consider individual care; continuity of care in macro-policy, when a shift to other levels of care is needed; intersectoriality was also included, when the needs of an individual and community require a cross-sectoral coordination, with action on determinants and conditionants of the health-disease process...
April 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29690416/revision-of-the-neotropical-genus-protoconnus-franz-coleoptera-staphylinidae-scydmaeninae
#15
PaweŁ JaŁoszyŃski
The Neotropical genus Protoconnus Franz, belonging to the tribe Glandulariini, is revised. Protoconnus is redefined based on detailed morphological study, and all known species are revised, including 10 originally placed in Protoconnus, one transferred from Euconnus, and 14 described as new. The following species are treated: P. andicola Franz (Peru), P. peruensis Franz (Peru), P. minutus Franz (Peru), P. minutissimus Franz (Peru), P. venezolanus Franz (Venezuela), P. araguanus Franz (Venezuela), P. bolivianus Franz (Bolivia), P...
March 7, 2018: Zootaxa
https://www.readbyqxmd.com/read/29690393/odd-species-of-nepticulidae-lepidoptera-from-the-american-rainforest-and-southern-andes
#16
Jonas R Stonis, Andrius Remeikis
In addition to numerous new species that can be placed to genera, our recent study of a large collection sample of Nepticulidae (Lepidoptera) from Central and South America revealed a few odd-looking new species, the taxonomic position of which seems rather problematic and, therefore, preliminary. Here we describe three new species of pygmy moths (Nepticulidae) from the Amazonian rainforest (Venezuela) and southern Andes (Chile and Argentina) possessing uncommon morphology. We also provide the first photographic documentation of the Central American Acalyptris argentosa (Puplesis Robinson, 2000) with rather odd and hitherto unknown hindwing scaling...
March 11, 2018: Zootaxa
https://www.readbyqxmd.com/read/29690204/review-of-the-helochares-hydrobaticus-macleay-of-the-new-world-coleoptera-hydrophilidae-acidocerinae
#17
Andrew Edward Z Short, Jennifer C GirÓn
New World species assigned to the Helochares subgenus Hydrobaticus MacLeay are reviewed based on adult morphology and DNA sequence data. Nine species are recognized, including five here described as new: Helochares (Hydrobaticus) laevis n. sp. (Mexico), H. (Hydrobaticus) nexus n. sp. (Ecuador, Panama, Venezuela), H. (Hydrobaticus) politus n. sp. (Guatemala), H. (Hydrobaticus) trujillo n. sp. (Venezuela), and H. (Hydrobaticus) zamora n. sp. (Ecuador). New records are provided for the three previously described species: Helochares (Hydrobaticus) championi Sharp, 1882 (Costa Rica, Guatemala, Nicaragua), H...
April 9, 2018: Zootaxa
https://www.readbyqxmd.com/read/29690091/two-new-species-of-euconnus-rhomboconnus-in-peru-and-bolivia-coleoptera-staphylinidae-scydmaeninae
#18
PaweŁ JaŁoszyŃski
To date, the subgenus Rhomboconnus Franz of Euconnus Thomson was represented by ten species known to occur in Venezuela, Panama and Ecuador. For the first time Rhomboconnus is reported to occur in Peru and Bolivia, and two new species are described: Euconnus wari sp. n. (Peru) and E. inkachakanus sp. n. (Bolivia). The latter species is the largest representative of Rhomboconnus, with body length exceeding 3 mm.
January 25, 2018: Zootaxa
https://www.readbyqxmd.com/read/29690044/a-new-species-of-cryptonympha-lugo-ortiz-mccafferty-ephemeroptera-baetidae-from-cerro-duida-venezuela
#19
TomÁŠ Derka, Carolina Nieto
The genus Cryptonympha includes three species: C. copiosa Lugo-Ortiz McCafferty, 1998; C. dasilvai Salles Francischetti, 2004 and C. genevievae Thomas, Manchon Glémet, 2013, known only from the nymphal stage. A description of the nymph of a fourth representative, Cryptonympha tracheata sp. n. is provided here, based on material collected in a blackwater stream on the slopes of the Cerro Duida mountain in south-western Venezuela. The nymph of the new species can be easily distinguished from the other species of the genus by very long tracheal gills II-VII, 2...
February 5, 2018: Zootaxa
https://www.readbyqxmd.com/read/29689903/the-genus-rosalba-thomson-1864-coleoptera-cerambycidae-lamiinae-apomecynini
#20
Antonio Santos-Silva, Maria Helena M Galileo, Luis J Joly, GÉrard L Tavakilian
Nineteen new species are described: Rosalba wappesi, from Bolivia; R. giesberti, from Bolivia; R. skillmani, from Bolivia; R. lingafelteri, from Bolivia; R. senecauxi, from French Guiana; R. dalensi, from French Guiana; R. giuglarisi, from French Guiana; R. nearnsi, from French Guiana; R. cerdai, from French Guiana; R. gaianii, from Venezuela; R. pittieri, from Venezuela; R. clinei, from Bolivia and Brazil; R. morrisi, from Costa Rica and Panama; R. schneppi, from Panama; R. birai, from Colombia; R. stenodesma, from Venezuela and French Guiana; R...
February 26, 2018: Zootaxa
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