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https://www.readbyqxmd.com/read/29656596/determination-of-a-suitable-low-dose-abdominopelvic-ct-protocol-using-model-based-iterative-reconstruction-through-cadaveric-study
#1
Fiachra Moloney, Maria Twomey, Daniel Fama, Joy Y Balta, Karl James, Richard G Kavanagh, Niamh Moore, Mary Jane Murphy, Siobhan M O'Mahony, Michael M Maher, John F Cryan, Owen J O'Connor
INTRODUCTION: Cadaveric studies provide a means of safely assessing new technologies and optimizing scanning prior to clinical validation. Reducing radiation exposure in a clinical setting can entail incremental dose reductions to avoid missing important clinical findings. The use of cadavers allows assessment of the impact of more substantial dose reductions on image quality. Our aim was to identify a suitable low-dose abdominopelvic CT protocol for subsequent clinical validation. METHODS: Five human cadavers were scanned at one conventional dose and three low-dose settings...
April 15, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29655486/comprehensive-simulation-on-morphological-and-mechanical-properties-of-trigger-finger-a-cadaveric-model
#2
Yu-Shiuan Cheng, Hsiao-Feng Chieh, Chien-Ju Lin, Li-Chieh Kuo, Kai-Nan An, Fong-Chin Su
Trigger finger has long been a common disorder in hand orthopedics. To clarify the unknown causative factors regarding the disease, numerous experiments were done on human cadavers, including tendon forces, tendon moment arm, mechanical properties of the pulley, gliding resistance, etc. However, most of these studies were conducted on normal fingers. As the etiology of trigger finger is still controversial on whether it is an outcome of tendon nodule or pulley scarring, in this study, a trigger finger model was built combining both the nodule created by silicone gel injection and pulley constriction by external compression...
March 30, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29652781/pelvic-incidence-is-associated-with-sacral-curvature-sacroiliac-joint-angulation-and-sacral-ala-width
#3
Matthew V Abola, Jason R Teplensky, Daniel R Cooperman, Jennifer M Bauer, Raymond W Liu
STUDY DESIGN: Cross-sectional anatomical study in dry cadaveric specimens OBJECTIVE.: This study evaluates how the sacroiliac (SI) joint angulation, midsagittal sacral curvature, and sacral ala width relate to pelvic incidence (PI). SUMMARY OF BACKGROUND DATA: Numerous spinopelvic pathologies have been linked with pelvic incidence; however, the manner in which sacral morphology fits into this association is largely unknown. METHODS: A total of 120 cadaveric sacra and corresponding innominate bones were obtained from an osteological collection...
April 12, 2018: Spine
https://www.readbyqxmd.com/read/29652192/achilles-pullout-strength-after-open-calcaneoplasty-for-haglund-syndrome
#4
Glenn Pfeffer, Tyler Gonzalez, Matthew Zapf, Trevor J Nelson, Melodie F Metzger
BACKGROUND: Haglund syndrome involves a prominent posterior superior prominence of the calcaneus. If nonoperative management fails, operative management with calcaneoplasty is often needed. No study has assessed Achilles tendon pullout strength after an open calcaneoplasty for Haglund syndrome. The purpose of this study was to investigate those changes in a cadaveric model and provide objective data upon which to base postoperative recovery. METHODS: Seven matched pairs of cadaveric specimens (mid-tibia to toes) were divided into 2 cohorts: (1) intact/untreated and (2) open resection...
April 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29651568/dorsal-extensions-of-the-fastigium-cerebelli-an-anatomical-study-using-magnetic-resonance-imaging
#5
Satoshi Tsutsumi, Juan Carlos Fernandez-Miranda, Hisato Ishii, Hideo Ono, Yukimasa Yasumoto
BACKGROUND AND PURPOSE: The fastigium cerebelli is an important topographical landmark for neurosurgeons and radiologists. However, few studies have characterized the morphology of the fastigium cerebelli. We aimed to investigate the fastigium cerebelli using postmortem specimens and magnetic resonance imaging (MRI) in vivo. MATERIALS AND METHODS: Three cadaveric brains were midsagittally sectioned for observing the fastigium cerebelli. Additionally, 66 outpatients underwent MRI, including sagittal T1-weighted imaging, axial T2-weighted imaging, and coronal constructive interference in steady-state (CISS) sequence...
April 12, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29651151/the-effect-of-ageing-and-osteoarthritis-on-the-mechanical-properties-of-cartilage-and-bone-in-the-human-knee-joint
#6
Abby E Peters, Riaz Akhtar, Eithne J Comerford, Karl T Bates
Osteoarthritis is traditionally associated with cartilage degeneration although is now widely accepted as a whole-joint disease affecting the entire osteochondral unit; however site-specific cartilage and bone material properties during healthy ageing and disease are absent limiting our understanding. Cadaveric specimens (n = 12; 31-88 years) with grades 0-4 osteoarthritis, were dissected and spatially correlated cartilage, subchondral and trabecular bone samples (n = 8 per cadaver) were harvested from femoral and tibial localities...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29649670/the-influence-of-the-twin-peg-design-on-femoral-interface-temperature-and-maximum-load-to-failure-in-cemented-oxford-unicompartmental-knee-arthroplasty
#7
Tobias Reiner, Martin Schwarze, Benjamin Panzram, Matthias C Klotz, Rudi G Bitsch, Sebastian Jaeger
BACKGROUND: The twin peg femoral component was introduced for the cemented Oxford unicondylar knee to increase implant stability. The aim of this experimental study was to investigate the influence of the twin peg design on femoral interface temperature and maximum load to failure in comparison to the single peg design. METHODS: In this experimental study medial Oxford unicompartmental knee arthroplasty was performed in 12 pairs of fresh-frozen human knees. A cemented femoral single peg component was implanted on the one side (group A) and a cemented twin peg component on the other side (group B)...
April 5, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29644415/does-simultaneous-liposuction-adversely-affect-the-outcome-of-thread-lifts-a-preliminary-result
#8
Yong Woo Lee, Tae Hwan Park
BACKGROUND: Along with advances in thread lift techniques and materials, ancillary procedures such as fat grafting, liposuction, or filler injections have been performed simultaneously. Some surgeons think that these ancillary procedures might affect the aesthetic outcomes of thread lifting possibly due to inadvertent injury to threads or loosening of soft tissue via passing the cannula in the surgical plane of the thread lifts. The purpose of the current study is to determine the effect of such ancillary procedures on the outcome of thread lifts in the human and cadaveric setting...
April 11, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29644164/the-extra-tunical-grafting-procedure-for-peyronie-s-disease-hourglass-and-indent-deformities
#9
Amanda B Reed-Maldonado, Amjad Alwaal, Tom F Lue
Background: To describe a novel, tunica-sparing surgical technique-extra-tunical grafting (ETG)-for the treatment of penile indent and hourglass (HG) deformities and to describe patient-reported outcomes after the ETG procedure. Methods: An IRB-approved, retrospective chart review of ETG patients was performed to collect data including pre-operative deformity, operation performed, and post-operative patient-reported perception of deformity, erectile function, penile sensation, and overall satisfaction with the ETG operation...
March 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29644144/comparative-effectiveness-of-a-bioengineered-living-cellular-construct-and-cryopreserved-cadaveric-skin-allograft-for-the-treatment-of-venous-leg-ulcers-in-a-real-world-setting
#10
Terry Treadwell, Michael L Sabolinski, Michelle Skornicki, Nathan B Parsons
Objective: A variety of advanced biological therapies are available for the treatment of chronic wounds such as venous leg ulcers (VLUs), but real-world comparative effectiveness data that can help guide decisions around treatments are currently lacking. Approach: This analysis was designed to compare the effectiveness of a bioengineered living cellular construct (BLCC) to a cryopreserved cadaveric skin allograft (CCSA) for the treatment of VLUs. Treatment records were collected from a large wound care-specific electronic medical record database on 717 patients (799 VLUs) receiving treatment at 177 wound care centers...
March 1, 2018: Advances in Wound Care
https://www.readbyqxmd.com/read/29644103/morphometric-study-of-the-semitendinosus-muscle-and-its-neurovascular-pedicles-in-south-indian-cadavers
#11
Rajanigandha Vadgaonkar, Manoor Dass Prameela, Bukkambudhi Virupakshamurthy Murlimanju, Mamatha Tonse, Chettiar Ganesh Kumar, Amit Massand, Vandana Blossom, Latha Venkatraya Prabhu
The purpose of this study was to determine the length of the semitendinosus muscle belly and its tendon in South Indian population and to study the topography and diameter of its neurovascular pedicles. The study included 46 formalin fixed human cadaveric lower limbs. The length of the semitendinosus muscle belly and its tendon were measured. The neurovascular pedicles of the semitendinosus muscle were identified and counted. The diameter of the neurovascular pedicle was measured just before its entrance into the semitendinosus muscle...
March 2018: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/29629804/quantitative-assessment-of-degenerative-cartilage-and-subchondral-bony-lesions-in-a-preserved-cadaveric-knee-propagation-based-phase-contrast-ct-versus-conventional-mri-and-ct
#12
Tobias Geith, Emmanuel Brun, Alberto Mittone, Sergei Gasilov, Loriane Weber, Silvia Adam-Neumair, Alberto Bravin, Maximilian Reiser, Paola Coan, Annie Horng
OBJECTIVE: The aim of this study was to quantitatively assess hyaline cartilage and subchondral bone conditions in a fully preserved cadaveric human knee joint using high-resolution x-ray propagation-based phase-contrast imaging (PBI) CT and to compare the performance of the new technique with conventional CT and MRI. MATERIALS AND METHODS: A cadaveric human knee was examined using an x-ray beam of 60 keV, a detector with a 90-mm2 FOV, and a pixel size of 46 × 46 μm2 ...
April 9, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29628315/a-bigger-suture-diameter-for-anterior-cruciate-ligament-all-inside-graft-link-preparation-leads-to-better-graft-stability-an-anatomical-specimen-study
#13
Thomas M Tiefenboeck, Lena Hirtler, Markus Winnisch, Julian Joestl, Thomas Koch, Micha Komjati, Marcus Hofbauer, Roman C Ostermann
BACKGROUND: In anterior cruciate ligament reconstruction, different suture types are used for graft link preparation. Thus the aim of this study was to determine whether differences in the diameter of the suture used influence biomechanical stability of the prepared graft. We hypothesized that the use of a greater suture diameter leads to a higher load to failure rate in tested graft links. METHODS: In an anatomic specimen study, ligament preparation was enrolled in 15 cadaveric knees...
April 5, 2018: Knee
https://www.readbyqxmd.com/read/29627930/flexor-digitorum-longus-tendon-transfer-to-the-navicular-tendon-to-tendon-repair-is-stronger-compared-with-interference-screw-fixation
#14
Daniel Marsland, Joanna M Stephen, Toby Calder, Andrew A Amis, James D F Calder
PURPOSE: To assess whether early rehabilitation could be safe after flexor digitorum longus (FDL) tendon transfer, the current biomechanical study aimed to measure tendon displacement under cyclic loading and load to failure, comparing a traditional tendon-to-tendon (TT) repair with interference screw fixation (ISF). METHODS: 24 fresh-frozen cadaveric below knee specimens underwent FDL tendon transfer. In 12 specimens a TT repair was performed via a navicular bone tunnel...
April 7, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29627641/occiput-axis-crossing-translaminar-screw-fixation-technique-using-offset-connectors-an-in-vitro-biomechanical-study
#15
Jiyong Gu, Weiwei Lei, Zong Xin, Yi Wu, Lin Peng, Zhibin Li, Zize Feng, Minchan Zhao, Songtao Qi, Yuntao Lu
OBJECTIVE: Fixation with the axis vertebra (C2) using pedicle screws is commonly used to treat an unstable occipitocervical junction; however, it is accompanied by a risk of vertebral artery injury. The occiput-C2 (OC2) crossing translaminar screw fixation technique may avoid this risk, but rod implantation is difficult. Offset connectors can help facilitate this construct. This study aimed to evaluate the stability of a technique for OC2 crossing translaminar screw fixation using offset connectors (C2LAM + OF) in comparison with other methods...
April 3, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29627610/three-dimensional-cad-cam-imaging-of-the-maxillary-sinus-in-ageing-process
#16
Kvetuse Lovasova, David Kachlik, Mirela Rozpravkova, Maria Matusevska, Jana Ferkova, Darina Kluchova
OBJECTIVES: During the physiological ageing process atrophy of the alveolar bone appears in vertical direction. This bone resorption causes pushing the limits of the maxillary sinus at the expense of a degraded bone. The sinus volume increases due to the facial development in children and adolescents or during the ageing process due to the loss of teeth and bone mass. The main aim of this study is to determine the sinus shape and sinus floor morphology related to age. MATERIALS AND METHODS: Human adult male and female cadaveric heads (aged 37 to 83 years) with different dental status were used...
April 5, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29627135/plantar-fascia-release-through-a-single-lateral-incision-in-the-operative-management-of-a-cavovarus-foot-a-cadaver-model-analysis-of-the-operative-technique
#17
Eric M Kiskaddon, Brett D Meeks, Joseph G Roberts, Richard T Laughlin
Plantar fascia release and calcaneal slide osteotomy are often components of the surgical management for cavovarus deformities of the foot. In this setting, plantar fascia release has traditionally been performed through an incision over the medial calcaneal tuberosity, and the calcaneal osteotomy through a lateral incision. Two separate incisions can potentially increase the operative time and morbidity. The purpose of the present study was threefold: to describe the operative technique, use cadaveric dissection to analyze whether a full release of the plantar fascia was possible through the lateral incision, and examine the proximity of the medial neurovascular structures to both the plantar fascia release and calcaneal slide osteotomy when performed together...
April 4, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29625919/ultrasound-guided-lateral-and-subcostal-transversus-abdominis-plane-block-in-calves-a-cadaveric-study
#18
Alessandro Mirra, Alois von Rotz, Marta Schmidhalter, Lara Moser, Daniela Casoni, Claudia Spadavecchia
OBJECTIVE: To describe and assess the ultrasound-guided transversus abdominis plane (TAP) block feasibility in calf cadavers, to compare two injection volumes and to evaluate possible undesired solution spreads. STUDY DESIGN: Prospective, descriptive, anatomic study. ANIMALS: A group of 15 bovine cadavers weighing 47±11 kg (mean±standard deviation). METHODS: Lateral (n = 24) and subcostal (n = 12) TAP block approaches were assessed...
March 15, 2018: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29625748/engineering-approaches-to-understanding-mechanisms-of-spinal-column-injury-leading-to-spinal-cord-injury
#19
REVIEW
Claire F Jones, Elizabeth C Clarke
BACKGROUND: The mechanical interactions occurring between the spinal column and spinal cord during an injury event are complex and variable, and likely have implications for the clinical presentation and prognosis of the individual. METHODS: The engineering approaches that have been developed to better understand spinal column and cord interactions during an injury event are discussed. These include injury models utilising human and animal cadaveric specimens, in vivo anaesthetised animals, finite element models, inanimate physical systems and combinations thereof...
March 28, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29625488/a-cell-culture-approach-to-optimized-human-corneal-endothelial-cell-function
#20
Alena Bartakova, Olga Kuzmenko, Karen Alvarez-Delfin, Noelia J Kunzevitzky, Jeffrey L Goldberg
Purpose: Cell-based therapies to replace corneal endothelium depend on culture methods to optimize human corneal endothelial cell (HCEC) function and minimize endothelial-mesenchymal transition (EnMT). Here we explore contribution of low-mitogenic media on stabilization of phenotypes in vitro that mimic those of HCECs in vivo. Methods: HCECs were isolated from cadaveric donor corneas and expanded in vitro, comparing continuous presence of exogenous growth factors ("proliferative media") to media without those factors ("stabilizing media")...
March 1, 2018: Investigative Ophthalmology & Visual Science
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