keyword
MENU ▼
Read by QxMD icon Read
search

MDRO

keyword
https://www.readbyqxmd.com/read/28528711/clinical-impact-of-colonization-with-multidrug-resistant-organisms-on-outcome-after-autologous-stem-cell-transplantation-a-retrospective-single-center-study
#1
Sebastian Scheich, Claudia Reinheimer, Christian Brandt, Thomas A Wichelhaus, Michael Hogardt, Volkhard A J Kempf, Uta Brunnberg, Christian Brandts, Olivier Ballo, Ivana von Metzler, Johanna Kessel, Hubert Serve, Björn Steffen
During the last years, a significant increase in infections caused by multidrug-resistant organisms (MDRO) has been noticed, resulting in an increase of mortality in all fields of healthcare. Hematological patients are particularly affected by MDRO infections due to disease- and therapy-related immunosuppression. To determine the impact of colonization with MDRO on overall survival, we retrospectively analyzed data from patients undergoing autologous hematopoietic stem cell transplantation at our institution...
May 18, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28513576/biofilm-is-a-major-virulence-determinant-in-bacterial-colonization-of-chronic-skin-ulcers-independently-from-the-multidrug-resistant-phenotype
#2
Enea Gino Di Domenico, Ilaria Farulla, Grazia Prignano, Maria Teresa Gallo, Matteo Vespaziani, Ilaria Cavallo, Isabella Sperduti, Martina Pontone, Valentina Bordignon, Laura Cilli, Alessandra De Santis, Fabiola Di Salvo, Fulvia Pimpinelli, Ilaria Lesnoni La Parola, Luigi Toma, Fabrizio Ensoli
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs). Nevertheless, a quantitative correlation between biofilm production and the profile of antimicrobial drug resistance in delayed wound healing remains to be determined. Microbial identification, antibiotic susceptibility and biofilm production were assessed in 135 clinical isolates from 87 patients. Gram-negative bacteria were the most represented microorganisms (60...
May 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28506784/healthcare-personnelintestinal-colonization-with-multidrug-resistant-organisms
#3
Brooke K Decker, Anna F Lau, John P Dekker, Christine D Spalding, Ninet Sinaii, Sean Conlan, David K Henderson, Julia A Segre, Karen M Frank, Tara N Palmore
OBJECTIVES: This study aims to assess the association between patient contact and intestinal carriageof multidrug-resistant organisms (MDRO) by sampling healthcare personnel (HCP) and staff without patient contact. METHODS: For this observational study, we recruited400HCPwho worked in our 200-bed research hospitaland 400 subjectswithout patient contact between November 2013 and February 2015.Participants submitted two self-collected perirectal swabsand a questionnaire...
May 12, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28502637/bathing-hospitalized-dependent-patients-with-prepackaged-disposable-washcloths-instead-of-traditional-bath-basins-a-case-crossover-study
#4
Emily Toth Martin, Samran Haider, Maria Palleschi, Sommer Eagle, Delfin V Crisostomo, Pamela Haddox, Laura Harmon, Robin Mazur, Judy Moshos, Dror Marchaim, Keith S Kaye
BACKGROUND: Basins used for patient bathing have been shown to be contaminated with multidrug-resistant organisms (MDROs) and have prompted the evaluation of alternatives to soap and water bathing methods. METHODS: We conducted a prospective, randomized, open-label interventional crossover study to assess the impact of replacing traditional bath basins with prepackaged washcloths on the incidence of hospital-associated infections (HAIs), MDROs, and secondarily, rates of skin deterioration...
May 11, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28475783/national-survey-of-practices-to-prevent-methicillin-resistant-staphylococcus-aureus-and-multidrug-resistant-acinetobacter-baumannii-in-thailand
#5
Anucha Apisarnthanarak, David Ratz, Thana Khawcharoenporn, Payal K Patel, David J Weber, Sanjay Saint, M Todd Greene
Background: We evaluated the extent to which hospital characteristics, infection control practices, and compliance with prevention bundles impacted multidrug-resistant organism (MDRO) infections in Thai hospitals. Methods: From 1 January 2014 to 30 November 2014, we surveyed all Thai hospitals with an intensive care unit and ≥250 beds. Infection control practices for methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Acinetobacter baumannii (MDR-AB) were assessed...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28473010/reduction-of-environmental-contamination-with-multidrug-resistant-bacteria-by-copper-alloy-coating-of-surfaces-in-a-highly-endemic-setting
#6
Maria Souli, Anastasia Antoniadou, Ioannis Katsarolis, Irini Mavrou, Elisabeth Paramythiotou, Evangelos Papadomichelakis, Maria Drogari-Apiranthitou, Theofano Panagea, Helen Giamarellou, George Petrikkos, Apostolos Armaganidis
OBJECTIVE To evaluate the efficacy of copper-coating in reducing environmental colonization in an intensive-care unit (ICU) with multidrug-resistant-organism (MDRO) endemicity DESIGN Interventional, comparative crossover trial SETTING The general ICU of Attikon University hospital in Athens, Greece PATIENTS Those admitted to ICU compartments A and B during the study period METHODS Before any intervention (phase 1), the optimum sampling method using 2 nylon swabs was validated. In phase 2, 6 copper-coated beds (ie, with coated upper, lower, and side rails) and accessories (ie, coated side table, intravenous [i...
May 5, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28441421/high-prevalence-of-mrsa-and-esbl-among-asylum-seekers-in-the-netherlands
#7
Sofanne J Ravensbergen, Matthijs Berends, Ymkje Stienstra, Alewijn Ott
Migration is one of the risk factors for the spread of multidrug-resistant organisms (MDRO). The increasing influx of migrants challenges local health care systems. To provide evidence for both hospital hygiene measure and empirical antibiotic therapy, we analysed all cultures performed in asylum seekers between January 1st 2014 and December 31st 2015 for methicillin resistant Staphylococcus aureus (MRSA) and for multidrug-resistant Enterobacteriaceae (MDRE). We compared these with cultures from the Dutch patient population with risk factors for carriage of MDRO...
2017: PloS One
https://www.readbyqxmd.com/read/28432607/impact-of-the-medical-specialty-on-knowledge-regarding-multidrug-resistant-organisms-and-strategies-toward-antimicrobial-stewardship
#8
Steffen Lebentrau, Christian Gilfrich, Malte W Vetterlein, Harald Schumacher, Philipp J Spachmann, Sabine D Brookman-May, Hans M Fritsche, Martin Schostak, Florian M Wagenlehner, Maximilian Burger, Matthias May
PURPOSE: Evidence is scarce on subject-specific knowledge of multidrug-resistant organisms and rational use of antibiotics. We aimed at evaluating attitude, perception, and knowledge about multidrug-resistant organisms (MDRO) and antibiotic prescribing among urologists versus other medical specialties. METHODS: Within the MR2-study (Multiinstitutional Reconnaissance of practice with MultiResistant bacteria), a questionnaire was conducted targeting general surgeons, internists, gynecologists, and urologists in 18 German hospitals...
April 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28431846/implementation-of-daily-chlorhexidine-bathing-to-reduce-colonization-by-multidrug-resistant-organisms-in-a-critical-care-unit
#9
Jackson S Musuuza, Ajay K Sethi, Tonya J Roberts, Nasia Safdar
BACKGROUND: Colonized patients are a reservoir for transmission of multidrug-resistant organisms (MDROs). Not many studies have examined the effectiveness of daily chlorhexidine gluconate (CHG) bathing under routine care conditions. We present a descriptive analysis of the trends of MDRO colonization following implementation of daily CHG bathing under routine clinical conditions in an intensive care unit (ICU). METHODS: From May 2010-January 2011, we screened patients admitted to a 24-bed ICU for and methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and fluoroquinolone-resistant gram-negative bacilli (FQRGNB)...
April 18, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28412380/colonization-by-multidrug-resistant-organisms-in-long-term-care-facilities-in-italy-a-point-prevalence-study
#10
Maria Giufrè, Enrico Ricchizzi, Marisa Accogli, Fabrizio Barbanti, Monica Monaco, Fernanda Pimentel de Araujo, Claudio Farina, Paolo Fazii, Romano Mattei, Mario Sarti, Agostino Barozzi, Rossella Buttazzi, Marina Cosentino, Maria Nardone, Vincenzo Savini, Patrizia Spigaglia, Annalisa Pantosti, Maria Luisa Moro, Marina Cerquetti
OBJECTIVES: This study aimed to determine prevalence and risk factors for colonization by multidrug-resistant organisms (MDROs) in long-term care facility (LTCF) residents in Italy. Genotypes of MDRO isolates were investigated. METHODS: A point-prevalence study was conducted at 12 LTCFs located in 4 Italian cities (2 February-14 March 2015). Rectal swabs, faeces and nasal/auxiliary swabs were cultured for extended-spectrum β-lactamase (ESBL)- and/or carbapenemase-producing Enterobacteriaceae, Clostridium difficile and methicillin-resistant Staphylococcus aureus (MRSA), respectively...
April 12, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28382547/challenges-and-strategies-for-prevention-of-multidrug-resistant-organism-transmission-in-nursing-homes
#11
REVIEW
Ghinwa Dumyati, Nimalie D Stone, David A Nace, Christopher J Crnich, Robin L P Jump
PURPOSE OF REVIEW: Nursing home residents are at high risk for colonization and infection with bacterial pathogens that are multidrug-resistant organisms (MDROs). We discuss challenges and potential solutions to support implementing effective infection prevention and control practices in nursing homes. RECENT FINDINGS: Challenges include a paucity of evidence that addresses MDRO transmission during the care of nursing home residents, limited staff resources in nursing homes, insufficient infection prevention education in nursing homes, and perceptions by nursing home staff that isolation and contact precautions negatively influence the well being of their residents...
April 2017: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/28378152/-development-of-antimicrobial-resistance-in-germany-what-is-the-current-situation
#12
F Maechler, C Geffers, F Schwab, L-A Peña Diaz, M Behnke, P Gastmeier
BACKGROUND: The frequency of multidrug-resistant organisms (MDRO) is increasing in Germany and worldwide. OBJECTIVES: Presentation of MDRO resistance rates and prevalence in Germany MATERIALS AND METHODS: Results from the Antibiotic Resistance Surveillance (ARS) and Hospital Infection Surveillance Systems (Krankenhausinfektions-Surveillance-Systems, KISS) and from recent prevalence surveys are presented. RESULTS: MRSA-resistance rates and the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) have remained at a stable level over the last few years...
April 4, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28341262/pulsed-xenon-ultraviolet-light-disinfection-in-a-burn-unit-impact-on-environmental-bioburden-multidrug-resistant-organism-acquisition-and-healthcare-associated-infections
#13
Caroline Green, Jeremy C Pamplin, Kristine N Chafin, Clinton K Murray, Heather C Yun
Portable pulsed xenon ultraviolet disinfection (PPX-UVD) may reduce healthcare associated infections (HAI). There is limited data to inform use in burn intensive care units (BICU), where multidrug-resistant organisms (MDRO), especially gram negative rods (GNR), commonly cause disease. We evaluated PPX-UVD effects on environmental bioburden and rates of HAI and MDRO acquisition in a BICU. PPX-UVD was used for 3 months after standard cleaning of patient and operating rooms (ORs). Settle and touch plates in patient rooms and ORs were obtained after standard cleaning, pre-and post-PPX-UVD...
March 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28322345/nursing-staff-fluctuation-and-pathogenic-burden-in-the-nicu-effective-outbreak-management-and-the-underestimated-relevance-of-non-resistant-strains
#14
Kai O Hensel, Rhea van den Bruck, Ingo Klare, Michael Heldmann, Beniam Ghebremedhin, Andreas C Jenke
In the course of a hospital management takeover, a microbial outbreak took place in a tertiary neonatal intensive care unit (NICU). Here, we characterize the outbreak and its management. About 4 months prior to takeover, there was a sharp increase in positive isolates for MSSA and multidrug-resistant organisms (MDROs). Simultaneously, the nursing staff sick leave rate increased dramatically which directly correlated with the number of infection/colonization per week (r(2) = 0.95, p = 0.02). During the following months we observed several peaks in positive isolates of methicillin-sensitive staphylococcus aureus (MSSA), MDROs and subsequently a vancomycin-resistant enterococcus (VRE) outbreak...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28319476/anesthesia-in-patients-with-infectious-disease-caused-by-multi-drug-resistant-bacteria
#15
Sharon Einav, Yonit Wiener-Well
PURPOSE OF REVIEW: Up to 50% of specific bacterial strains in healthcare admission facilities are multi-drug resistant organisms (MDROs). Involvement of anesthesiologists in management of patients carrying/at risk of carrying MDROs may decrease transmission in the Operating Room (OR). RECENT FINDINGS: Anesthesiologists, their work area and tools have all been implicated in MDRO outbreaks. Causes include contamination of external ventilation circuits and noncontribution of filters to prevention, inappropriate decontamination procedures for nondisposable equipment (e...
June 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28291632/necessity-of-carbapenem-use-when-prescribed-per-infectious-diseases-specialists
#16
Kellie J Goodlet, Michael D Nailor
Preauthorization strategies, including restricting broad-spectrum antimicrobials such as carbapenems to infectious diseases physicians (ID) are commonly employed by stewardship programs. The appropriateness, or "necessity" of empiric carbapenem therapy by ID, defined as an isolated organism sensitive to the carbapenem and resistant to cefepime, was evaluated over a 6month span and included 84 patients. Additionally, 30 patients followed by ID who were not prescribed a carbapenem until final susceptibilities were included as a definitive therapy group...
May 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28285725/universal-versus-targeted-additional-contact-precautions-for-multidrug-resistant-organism-carriage-for-patients-admitted-to-an-intensive-care-unit
#17
Michel Djibré, Samuel Fedun, Pierre Le Guen, Sophie Vimont, Mehdi Hafiani, Jean-Pierre Fulgencio, Antoine Parrot, Michel Denis, Muriel Fartoukh
BACKGROUND: Although additional contact precautions (ACPs) are routinely used to reduce cross-transmission of multidrug-resistant organisms (MDROs), the relevance of isolation precautions remains debated. We hypothesized that the collection of recognized risk factors for MDRO carriage on intensive care unit (ICU) admission might be helpful to target ACPs without increasing MDRO acquisition during ICU stays, compared with universal ACPs. MATERIALS AND METHODS: This is a sequential single-center observational study performed in consecutive patients admitted to a French medical and surgical ICU...
March 10, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28270258/the-impact-of-reducing-antibiotics-on-the-transmission-of-multidrug-resistant-organisms
#18
Sean L Barnes, Clare Rock, Anthony D Harris, Sara E Cosgrove, Daniel J Morgan, Kerri A Thom
OBJECTIVE Antibiotic resistance is a major threat to public health. Resistance is largely driven by antibiotic usage, which in many cases is unnecessary and can be improved. The impact of decreasing overall antibiotic usage on resistance is unknown and difficult to assess using standard study designs. The objective of this study was to explore the potential impact of reducing antibiotic usage on the transmission of multidrug-resistant organisms (MDROs). DESIGN We used agent-based modeling to simulate interactions between patients and healthcare workers (HCWs) using model inputs informed by the literature...
March 8, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28216179/the-17th-international-congress-on-infectious-diseases-workshop-on-developing-infection-prevention-and-control-resources-for-low-and-middle-income-countries
#19
Sangeeta Sastry, Nadia Masroor, Gonzalo Bearman, Rana Hajjeh, Alison Holmes, Ziad Memish, Britta Lassmann, Didier Pittet, Fiona Macnab, Rachel Kamau, Evelyn Wesangula, Paras Pokharel, Paul Brown, Frances Daily, Fatma Amer, Jaime Torres, Miguel O'Ryan, Revathi Gunturu, Andre Bulabula, Shaheen Mehtar
Hospital-acquired infections (HAIs) are a major concern to healthcare systems around the world. They are associated with significant morbidity and mortality, in addition to increased hospitalization costs. Recent outbreaks, including those caused by the Middle East respiratory syndrome coronavirus and Ebola virus, have highlighted the importance of infection control. Moreover, HAIs, especially those caused by multidrug-resistant Gram-negative rods, have become a top global priority. Although adequate approaches and guidelines have been in existence for many years and have often proven effective in some countries, the implementation of such approaches in low- and middle-income countries (LMICs) is often restricted due to limited resources and underdeveloped infrastructure...
February 16, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28211567/isolation-precautions-use-for-multidrug-resistant-organism-infection-in-nursing-homes
#20
Catherine C Cohen, Andrew Dick, Patricia W Stone
OBJECTIVES: To examine factors associated with isolation precaution use in nursing home (NH) residents with multidrug-resistant organism (MDRO) infection. DESIGN: Retrospective, cross-sectional analysis. SETTING: Nursing homes with Centers for Medicare and Medicaid Services' certification from October 2010 to December 2013. PARTICIPANTS: Elderly, long-stay NH residents with positive MDRO infection assessments. MEASUREMENTS: Data were obtained from the Minimum Data Set (MDS) 3...
March 2017: Journal of the American Geriatrics Society
keyword
keyword
9738
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"