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https://www.readbyqxmd.com/read/29340656/antagonistic-effect-of-saccharomyces-cerevisiae-ktp-and-issatchenkia-occidentalis-apc-on-hyphal-development-and-adhesion-of-candida-albicans
#1
K Lohith, K A Anu-Appaiah
The morphological transition from yeast to a hyphal form, as well as the adhesion capability to the gastrointestinal tract, are implicated virulent determinant in Candida albicans and could be potential targets for prevention of the opportunistic pathogen. Based on this rationale, two yeast strains Saccharomyces cerevisiae KTP and Issatchenkia occidentalis ApC along with reference strain Saccharomyces boulardii NCDC 363 were screened for the probiotic potential. Characters like pH, temperature, bile, simulated gastrointestinal juice tolerance tests, and Caco-2 cell line adhesion assay were determined in the present study...
January 11, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29338077/blenderized-enteral-nutrition-diet-study-feasibility-clinical-and-microbiome-outcomes-of-providing-blenderized-feeds-through-a-gastric-tube-in-a-medically-complex-pediatric-population
#2
Kelsey Gallagher, Annika Flint, Marialena Mouzaki, Andrea Carpenter, Beth Haliburton, Louise Bannister, Holly Norgrove, Lisa Hoffman, David Mack, Alain Stintzi, Margaret Marcon
BACKGROUND: Chronically ill children often require feeding via gastrostomy tubes (G-tubes). Commercial formula is most commonly used for enteral feeding; however, caregivers have been requesting blenderized tube feeds (BTFs) as an alternative. The objective of this study was to evaluate the feasibility of using BTFs in a medically complex pediatric population and assess their impact on clinical outcomes, as well as the microbiota. METHODS: Twenty pediatric participants were included...
January 16, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29327864/limits-of-endoscopic-endonasal-approach-for-cranio-vertebral-junction-tumors
#3
Matteo Zoli, Nicolò Rossi, Filippo Friso, Carmelo Sturiale, Giorgio Frank, Ernesto Pasquini, Diego Mazzatenta
INTRODUCTION: The endoscopic endonasal approach has been recently proposed for cranio-vertebral junction lesions. The more common indication for this sagittal extension of the endonasal route is represented by odontoidectomy for irreducible ventral brainstem compression due to congenital or degenerative conditions. However, in an increasing number of studies its adoption for tumors involving the cranio-cervical junction has been reported. The aim of this study is to consider retrospectively our surgical series, focusing on the advantages and limits of this approach...
January 10, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29284856/proseal-laryngeal-mask-airway-versus-cuffed-endotracheal-tube-for-laparoscopic-surgical-procedures-under-general-anesthesia-a-random-comparative-study
#4
Suchita Shailesh Parikh, Shivam Bipin Parekh, Chaula Doshi, Varsha Vyas
Context: The Proseal LMA(PLMA), which has been designed especially for positive pressure ventilation and protection against aspiration can act as an alternative to Endotracheal Tube (ETT) as an effective airway device for patients undergoing elective Laparoscopic surgeries. Aims: To compare the efficacy and safety of PLMA with ETT in patients undergoing Laparoscopic surgeries under general anaesthesia. Settings and Design: A prospective, randomized study was conducted in a tertiary care teaching hospital with 60 patients of ASA grade I/II undergoing elective Laparoscopic surgery under general anaesthesia...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29277806/utility-of-nasogastric-tube-for-medical-and-surgical-oncology-of-gastric-cancer-a-prospective-institutional-study-on-a-new-and-precious-application-of-an-old-and-economic-device
#5
Edoardo Virgilio, Genoveffa Balducci, Paolo Mercantini, Enrico Giarnieri, Maria Rosaria Giovagnoli, Monica Montagnini, Antonella Proietti, Rosaria D'Urso, Marco Cavallini
BACKGROUND/AIM: Concerning gastric cancer (GC), nasogastric tube (NGT) is routinely employed for peri-operative decompression and palliative enteral nutrition. Additionally, we believe to have found a further application. PATIENTS AND METHODS: Between April 2012 and April 2017, 96 GC patients received preoperative nasogastric lavage (GL). All samples were cytologically examined to detect the presence (GL1) or absence (GL0) of malignant cells. Data were analyzed with classificatory, staging and prognostic purpose...
January 2018: Anticancer Research
https://www.readbyqxmd.com/read/29261527/preoperative-evaluation-is-not-predictive-of-transpyloric-feeding-conversion-in-gastrostomy-dependent-pediatric-patients
#6
Maireade McSweeney, Jessica Kerr, Janine Amirault, Eliza Fishman, Margot Lurie, Maria I Peinado-Fabregat, Paul D Mitchell, Rachel Rosen
OBJECTIVES: Limited literature exists as to whether preoperative gastrostomy (GT)evaluation may predict which patients will go onto require gastrojejunostomy tube (GJ) feeding. The goal of this study was to compare the preoperative evaluations between patients maintained on GT feeds versus patients who required conversion to GJ feeds. METHODS: We identified patients at Boston Children's Hospital who underwent GT placement and required GJ feeding between 2006-2012...
December 19, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29259379/two-step-method-for-creating-a-gastric-tube-during-laparoscopic-thoracoscopic-ivor-lewis-esophagectomy
#7
Yu Liu, Ji-Jia Li, Peng Zu, Hong-Xu Liu, Zhan-Wu Yu, Yi Ren
AIM: To introduce a two-step method for creating a gastric tube during laparoscopic-thoracoscopic Ivor-Lewis esophagectomy and assess its clinical application. METHODS: One hundred and twenty-two patients with middle or lower esophageal cancer who underwent laparoscopic-thoracoscopic Ivor-Lewis esophagectomy at Liaoning Cancer Hospital and Institute from March 2014 to March 2016 were included in this study, and divided into two groups based on the procedure used for creating a gastric tube...
December 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29258438/supreme%C3%A2-laryngeal-mask-airway-use-in-general-anesthesia-for-category-2-and-3-cesarean-delivery-a-prospective-cohort-study
#8
Shi Yang Li, Wei Yu Yao, Yong Jin Yuan, Wen Shu Tay, Nian-Lin Reena Han, Rehena Sultana, Pryseley N Assam, Alex Tiong-Heng Sia, Ban Leong Sng
BACKGROUND: The Supreme™ laryngeal mask airway (SLMA) is a single-use LMA with double lumen design that allows separation of the respiratory and the alimentary tract, hence potentially reducing the gastric volume and risk of aspiration. The purpose of this prospective cohort study is to evaluate the the role of the SLMA as an airway technique for women undergoing category 2 and 3 Cesarean delivery under general anesthesia. METHODS: We recruited 584 parturients who underwent category 2 or 3 Cesarean delivery under general anesthesia, in which 193 parturients underwent category 2 and 391 parturients underwent category 3 Cesarean delivery...
December 19, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/29250583/slow-growing-amelanotic-malignant-melanoma-of-the-esophagus-with-long-survival-a-case-report-and-review-of-the-literature
#9
Yutaka Hirayama, Tajika Masahiro, Tsutomu Tanaka, Makoto Ishihara, Sachiyo Ohnishi, Kazuo Hara, Nobumasa Mizuno, Susumu Hijioka, Nozomi Okuno, Tetsuya Abe, Norihisa Uemura, Jiro Kawakami, Shintarou Kurahashi, Yasuhiro Shimizu, Yasushi Yatabe, Yasumasa Niwa
Background and study aims  We report a case of amelanotic malignant melanoma of the esophagus (AMME), an exceedingly rare disease. A 77-year-old Japanese woman presented to our hospital with features suggestive of a middle esophageal submucosal tumor, which was diagnosed pathologically as AMME. The patient underwent thoracoscopic resection of the esophagus and laparoscopic gastric tube reconstruction. Three years after surgery, computed tomography showed no recurrence. Generally, the prognosis of malignant melanoma of the esophagus is very poor...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29246751/generation-and-characterization-of-an-anti-delta-like-ligand-4-nanobody-to-induce-non-productive-angiogenesis
#10
Rasoul Baharlou, Nader Tajik, Mahdi Behdani, Mohammad Ali Shokrgozar, Amir Hassan Zarnani, Fatemeh Shahhosseini, Mahdi Habibi-Anbouhi
Antibody-based targeting of angiogenesis is a key approach for cancer treatment. Delta-like ligand 4 (DLL4) plays a pivotal role in tumor neovascular development and angiogenesis during tumor progression. It forecasts the prognosis of human malignancies and blocking its signaling can help to inhibit neovascularization and tumor metastasis. Nanobodies are the smallest antigen-binding domains of heavy chain antibodies in camelidae. The aim of this study was to develop a Nanobody against DLL4 and apply binding and functional approaches to target it...
December 12, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/29245951/construction-of-a-model-predicting-the-risk-of-tube-feeding-intolerance-after-gastrectomy-for-gastric-cancer-based-on-225-cases-from-a-single-chinese-center
#11
Wu Xiaoyong, Li Xuzhao, Yu Deliang, Yu Pengfei, Hang Zhenning, Bai Bin, Li Zhengyan, Pang Fangning, Wang Shiqi, Zhao Qingchuan
Identifying patients at high risk of tube feeding intolerance (TFI) after gastric cancer surgery may prevent the occurrence of TFI; however, a predictive model is lacking. We therefore analyzed the incidence of TFI and its associated risk factors after gastric cancer surgery in 225 gastric cancer patients divided into without-TFI (n = 114) and with-TFI (n = 111) groups. A total of 49.3% of patients experienced TFI after gastric cancer. Multivariate analysis identified a history of functional constipation (FC), a preoperative American Society of Anesthesiologists (ASA) score of III, a high pain score at 6-hour postoperation, and a high white blood cell (WBC) count on the first day after surgery as independent risk factors for TFI...
November 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/29243194/kallistatin-inhibits-lymphangiogenesis-and-lymphatic-metastasis-of-gastric-cancer-by-downregulating-vegf-c-expression-and-secretion
#12
Caiqi Ma, Chuanghua Luo, Haofan Yin, Yang Zhang, Wenjun Xiong, Ting Zhang, Tianxiao Gao, Xi Wang, Di Che, Zhenzhen Fang, Lei Li, Jinye Xie, Mao Huang, Liuqing Zhu, Ping Jiang, Weiwei Qi, Ti Zhou, Zhonghan Yang, Wei Wang, Jianxing Ma, Guoquan Gao, Xia Yang
BACKGROUND: Tumor-induced lymphangiogenesis and lymphatic metastasis are predominant during the metastasis of many types of cancers. However, the endogenous inhibitors that counterbalance the lymphangiogenesis and lymphatic metastasis of tumors have not been well evaluated. Kallistatin has been recognized as an endogenous angiogenesis inhibitor. METHODS AND RESULTS: Our recent study showed for the first time that the lymphatic vessel density (LVD) was reduced in lung and stomach sections from kallistatin-overexpressing transgenic mice...
December 14, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29238893/postprandial-cardiogenic-syncope-caused-by-gastric-polyp-induced-pyloric-obstruction-in-an-elderly-woman-with-a-giant-hiatal-hernia-a-case-report
#13
Hideyuki Saito, Tatsuya Miyazaki, Makoto Sohda, Makoto Sakai, Hiroaki Honjyo, Yuuji Kumakura, Tomonori Yoshida, Takehiko Yokobori, Koji Kurosawa, Hiroyuki Kuwano
BACKGROUND: Hiatal hernias are common. In some reports, hiatal hernias have been implicated in causing dyspnea, syncope, and heart failure. CASE PRESENTATION: An 82-year-old woman with a hiatal hernia was admitted to our hospital because she had experienced postprandial syncope during the last few years. Esophagogastroduodenoscopy revealed a large hiatal hernia and a pedunculated polyp of the stomach antrum that fit into the pylorus. An upper gastrointestinal contrast study showed that the entire stomach had relocated to the thoracic cavity and that the body of the stomach was located above the fundus, resulting in a so-called upside-down stomach...
December 13, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29233028/therapeutic-effects-of-oral-liothyronine-on-aluminum-phosphide-poisoning-as-an-adjuvant-therapy-a-clinical-trial
#14
M H Goharbari, F Taghaddosinejad, M Arefi, M Sharifzadeh, M Mojtahedzadeh, S Nikfar, M Baeeri, M Rahimifard, M Abdollahi
BACKGROUND: In aluminum phosphide (AlP) poisoning, death is mainly due to cardiovascular failure and refractory acute heart failure. There is a lot of evidence showing thyroid hormones have cardioprotective effects. OBJECTIVE: The purpose of this study was to evaluate the effect of oral liothyronine in the treatment of AlP poisoning. METHODS: Twenty-four patients from intensive care unit of Baharloo Hospital, Tehran, Iran, were included based on the inclusion and exclusion criteria...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29224771/revision-repair-of-type-iv-laryngotracheoesophageal-cleft-using-multiple-long-tapered-engaging-grafts
#15
Evan J Propst
An 8 year-old female with esophageal atresia and a type IV laryngotracheoesophageal cleft underwent tracheostomy, gastric pull-up and fundoplication with G-tube insertion at birth. She remained nil per os due to aspiration. The trachealis was separated from the esophagus that was reapproximated and clavicular periosteum was placed. A long posterior costal cartilage graft that engaged behind the cricoid plate and tapered inferiorly was inserted. A second thin cartilage graft was sutured to it distally to extend the length of the repair...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29223168/serious-gastric-perforation-after-second-stereotactic-body-radiotherapy-for-peripheral-lung-cancer-that-recurred-after-initial-stereotactic-body-radiotherapy-a-case-report
#16
Hotaka Nonaka, Hiroshi Onishi, Masatoki Ozaki, Kengo Kuriyama, Takafumi Komiyama, Ryo Saito
BACKGROUND: In recent reports, re-irradiation with stereotactic body radiotherapy for lung tumors in patients previously treated with thoracic radiation therapy resulted in several serious toxicities. Serious non-lung toxicities were observed mostly in patients with central tumors, but we experienced a case of fatal gastric perforation after a second stereotactic body radiotherapy in a patient with a peripheral lung tumor. CASE PRESENTATION: An 83-year-old Asian man was diagnosed with T2N0M0 lung cancer in the form of squamous cell carcinoma in the lower lobe of his left lung...
December 10, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29218657/comparison-of-laparoscopic-jejunostomy-tube-to-percutaneous-endoscopic-gastrostomy-tube-with-jejunal-extension-long-term-durability-and-nutritional-outcomes
#17
Ivy N Haskins, Andrew T Strong, Mary Baginsky, Gautam Sharma, Matthew Karafa, Jeffrey L Ponsky, John H Rodriguez, Matthew D Kroh
INTRODUCTION: Enteral access through the jejunum is indicated when patients cannot tolerate oral intake or gastric feeding. While multiple approaches for feeding jejunal access exist, few studies have compared the efficacy of these techniques. The purpose of this study was to investigate the long-term durability, re-intervention rates, and nutritional outcomes following percutaneous endoscopic gastrostomy tubes with jejunal extension tubes (PEG-JET) versus laparoscopic jejunostomy tubes (j-tubes)...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29218217/gastric-band-tubing-related-complication-during-pregnancy
#18
Yuni F Ongso, Han N Beh
In the past few decades, laparoscopic adjustable gastric banding is one of the most common bariatric procedures performed to treat morbid obesity. Device-related complication such as connection-tubing problem is rare. Here we present a case of gastric band tubing complication during pregnancy. This case illustrates the need to maintain high index of suspicion of gastric band device-related complication during pregnancy and early referral for bariatric surgical assessment is recommended.
November 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29211685/optimisation-of-sampling-parameters-for-standardised-exhaled-breath-sampling
#19
Sophie L F Doran, Andrea Romano, George B Hanna
The lack of standardisation of breath sampling is a major contributing factor to the poor repeatability of results and hence represents a barrier to the adoption of breath tests in clinical practice. On-line and bag breath sampling have advantages but do not suit multicentre clinical studies whereas storage and robust transport are essential for the conduct of wide-scale studies. Several devices have been developed to control sampling parameters and to concentrate volatile organic compounds (VOCs) onto thermal desorption (TD) tubes and subsequently transport those tubes for laboratory analysis...
December 6, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/29211227/resection-of-left-atrial-myxoma-in-a-patient-with-retrosternal-gastric-tube-a-case-report
#20
Pablo Maria Alberto Pomerantzeff, Elinthon Tavares Veronese, Fabrício José Dinato, Fabio Biscegli Jatene
The median sternotomy remains the standard approach in cardiovascular surgery but, in some conditions, it can be considered difficult to perform, especially in patients with history of esophagectomy. This case report describes a successful resection of a left atrial myxoma through a right anterolateral thoracotomy approach in a patient with a previous retrosternal gastric tube reconstruction. The decision for the best surgical approach was made after a heart surgery team discussion. Through this surgical access, a safe and excellent exposure of the left atrium was possible, and a complete resection of the myxoma was performed without any injury to the gastric tube...
September 2017: Brazilian Journal of Cardiovascular Surgery
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