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https://www.readbyqxmd.com/read/28339695/incidence-and-outcomes-of-infections-caused-by-multidrug-resistant-enterobacteriaceae-in-children-2007-2015
#1
Sharon B Meropol, Allison A Haupt, Sara M Debanne
Background.: The escalating incidence of invasive disease caused by multidrug-resistant Gram-negative enteric Enterobacteriaceae (MDR-GNE) is a global concern. Scant published studies in which the epidemiology of these infections in children is described exist; previous studies focused mainly on adults, described circumscribed populations, or lacked clinical detail. The objective of this study was to examine and describe the incidence, risk factors, and outcomes associated with MDR-GNE infection in children...
February 22, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28334179/bayesian-distributed-lag-interaction-models-to-identify-perinatal-windows-of-vulnerability-in-children-s-health
#2
Ander Wilson, Yueh-Hsiu Mathilda Chiu, Hsiao-Hsien Leon Hsu, Robert O Wright, Rosalind J Wright, Brent A Coull
Epidemiological research supports an association between maternal exposure to air pollution during pregnancy and adverse children's health outcomes. Advances in exposure assessment and statistics allow for estimation of both critical windows of vulnerability and exposure effect heterogeneity. Simultaneous estimation of windows of vulnerability and effect heterogeneity can be accomplished by fitting a distributed lag model (DLM) stratified by subgroup. However, this can provide an incomplete picture of how effects vary across subgroups because it does not allow for subgroups to have the same window but different within-window effects or to have different windows but the same within-window effect...
February 27, 2017: Biostatistics
https://www.readbyqxmd.com/read/28332359/burdens-of-cardiometabolic-diseases-attributable-to-dietary-and-metabolic-risks-in-korean-adults-2012-2013
#3
Yoonsu Cho, Frederick Cudhea, Ju Hyun Park, Dariush Mozaffarian, Gitanjali Singh, Min Jeong Shin
PURPOSE: In line with epidemiological and sociocultural changes in Korea over the past decades, reliable estimation of diseases as a result of dietary and metabolic risks is required. In this study, we aimed to evaluate the contributions of dietary and metabolic factors to cardiometabolic diseases (CMDs) in Korean adults (25-64 years old) during 2012-2013. MATERIALS AND METHODS: Distribution of risk factors and cause-specific mortality by gender and age per year was obtained from the Korea National Health and Nutrition Examination Survey and Statistics Korea, respectively...
May 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28327798/molecular-and-clinical-epidemiological-surveillance-of-dengue-virus-in-para%C3%A3-ba-northeast-brazil
#4
Isabel Cristina Guerra-Gomes, Bruna Macêdo Gois, Rephany Fonseca Peixoto, Camila Alves Oliveira, Bruna Leal Lima Maciel, Maria Izabel Ferreira Sarmento, Anna Stella Cysneiros Pachá, Josélio Maria Galvão Araújo, Ian Porto Gurgel Amaral, Tatjana Souza Lima Keesen
INTRODUCTION: Despite being the most prevalent arboviral disease worldwide, dengue has been neglected lately. However, recent epidemics of arboviruses such as Zika and chikungunya in locations throughout the world have alerted health authorities to these diseases. This study evaluated the incidence pattern of dengue, its clinical characteristics, and co-circulation of serotypes from 2007 to 2015 in Paraiba State, Northeast Brazil. METHODS: Data on dengue cases from 2007 to 2015 were extracted from clinical reports of the National System for Notifiable Diseases [Sistema Nacional de Agravos de Notificação (SINAN)] of Brazil provided by the Paraiba Health Department...
January 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28324921/epidemiology-of-intracranial-metastases-in-korea-a-national-cohort-investigation
#5
Tackeun Kim, Changhoon Song, Jung Ho Han, In-Ah Kim, Yu Jung Kim, Se Hyun Kim, Jee Hyun Kim, Chae-Yong Kim
Purpose: To investigate the epidemiologic features of intracranial metastases (ICMET) in Korea, we performed a cohort study using the National Health Insurance Service-National Sample Cohort database, which comprised healthcare usage information of approximately 1 million Korean individuals over 12 years. Materials and Methods: We enrolled 998,602 subjects, after excluding 18,218 subjects diagnosed with any cancer during the washout period (2002-2004). The observation period was 9 years (2005-2013; 8,725,438 person-years)...
March 21, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28324321/structured-data-entry-in-the-electronic-medical-record-perspectives-of-pediatric-specialty-physicians-and-surgeons
#6
Ruth A Bush, Cynthia Kuelbs, Julie Ryu, Wen Jiang, George Chiang
The Epic electronic health record (EHR) platform supports structured data entry systems (SDES), which allow developers, with input from users, to create highly customized patient-record templates in order to maximize data completeness and to standardize structure. There are many potential advantages of using discrete data fields in the EHR to capture data for secondary analysis and epidemiological research, but direct data acquisition from clinicians remains one of the largest obstacles to leveraging the EHR for secondary use...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28323463/injury-mortality-in-individuals-with-autism
#7
Joseph Guan, Guohua Li
OBJECTIVES: To examine epidemiological patterns of injury fatalities in individuals with a diagnosis of autism. METHODS: We identified individuals with a diagnosis of autism who died between 1999 and 2014 by screening causes of death in the multiple cause-of-death data files in the National Vital Statistics System based on the International Classification of Diseases, 10th Revision, code F84.0. We used the general US population as the reference to calculate proportionate mortality ratios (PMRs) and 95% confidence intervals (CIs)...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28322313/the-epidemic-dynamics-of-hepatitis-c-virus-subtypes-4a-and-4d-in-saudi-arabia
#8
Ahmed A Al-Qahtani, Guy Baele, Nisreen Khalaf, Marc A Suchard, Mashael R Al-Anazi, Ayman A Abdo, Faisal M Sanai, Hamad I Al-Ashgar, Mohammed Q Khan, Mohammed N Al-Ahdal, Philippe Lemey, Bram Vrancken
The relatedness between viral variants sampled at different locations through time can provide information pertinent to public health that cannot readily be obtained through standard surveillance methods. Here, we use virus genetic data to identify the transmission dynamics that drive the hepatitis C virus subtypes 4a (HCV4a) and 4d (HCV4d) epidemics in Saudi Arabia. We use a comprehensive dataset of newly generated and publicly available sequence data to infer the HCV4a and HCV4d evolutionary histories in a Bayesian statistical framework...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28319125/spatio-temporal-patterns-of-gun-violence-in-syracuse-new-york-2009-2015
#9
David A Larsen, Sandra Lane, Timothy Jennings-Bey, Arnett Haygood-El, Kim Brundage, Robert A Rubinstein
Gun violence in the United States of America is a large public health problem that disproportionately affects urban areas. The epidemiology of gun violence reflects various aspects of an infectious disease including spatial and temporal clustering. We examined the spatial and temporal trends of gun violence in Syracuse, New York, a city of 145,000. We used a spatial scan statistic to reveal spatio-temporal clusters of gunshots investigated and corroborated by Syracuse City Police Department for the years 2009-2015...
2017: PloS One
https://www.readbyqxmd.com/read/28316764/the-association-between-oral-hygiene-and-gastric-pathology-in-patients-with-dyspepsia-a-cross-sectional-study-in-southeast-iran
#10
Leili Zahedi, Elham Jafari, Molook Torabi Parizi, Sara Shafieipour, Mehdi Hayat Bakhsh Abbasi, Sodaif Darvish Moghadam, Mohammad Javad Zahedi
BACKGROUND Many studies have reported an association between periodontal infections and some systemic diseases such as respiratory and cardiovascular diseases. Some studies found a direct association between chronic gastritis caused by Helicobacter pylori (HP) infection and poor periodontal health. METHODS In a cross-sectional study from November 2014 to December 2015 in Kerman, the largest province in southeast Iran, patients with dyspepsia who were candidate for diagnostic upper gastrointestinal (GI) endoscopy were included in our study...
January 2017: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28316401/prevalence-and-molecular-characterization-of-cryptosporidium-species-in-cattle-and-buffalo-calves-in-mumbai-region-of-india
#11
A C Hingole, J G Gudewar, R P Pednekar, M L Gatne
Faecal samples of cattle and buffaloes of Mumbai region collected between November 2012 to June 2013 were analysed by conventional and molecular tools to note the prevalence of cryptosporidiosis and species involved in the infection. Conventional analysis viz., direct faecal smear examination, faecal smear examination after normal saline sedimentation, Sheather's floatation and Sheather's floatation sedimentation smear methods demonstrated oocysts of Cryptosporidium in 141 (36.06 %) of 391 samples with higher occurrence in buffaloes (36...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28314544/comprehensive-assessments-of-long-term-sleep-habits-in-epidemiological-study-validity-and-reliability-of-sleep-factors-questionnaire-sfq-among-chinese-women
#12
Wan-Shui Yang, Wen-Xue Fu, Xin Wang, Qin Deng, Ling Wang, Lin-Yan Wang, Hao Zhao, Wen-Yan Fan, Shao-Xin Huang
OBJECTIVE: Epidemiological studies suggested that poor sleep is a potentially novel risk factor for several health outcomes currently; however, there are no validated questionnaires that can systematically measure sleep parameters within these studies. We evaluated the reliability and validity of 17-item sleep factors questionnaire (SFQ), which was developed to comprehensively assess long-term sleep habits for the Jiujiang Breast Cancer Study (JBCS), Jiujiang, China. METHODS: The participants included 100 women aged 18-74years, who were randomly selected from the JBCS project, and completed a SFQ at baseline and again 1year later, and 4 quarterly 30 consecutive days (a total of 120days) sleep diaries over this same year...
April 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28295797/overweight-or-obesity-in-children-aged-0-to-6-and-the-risk-of-adult-metabolic-syndrome-a-systematic-review-and-meta-analysis
#13
REVIEW
Jieun Kim, Insook Lee, Sungwon Lim
AIMS AND OBJECTIVES: To identify an association between overweight or obesity in early childhood and metabolic syndrome in adults. BACKGROUND: Early childhood overweight or obesity is important because it can predict metabolic syndrome in adulthood. A longer period of overweight or obesity leads to the accumulation of more risk factors. However, there are insufficient and inconsistent studies on this issue. DESIGN: A systematic review and meta-analysis...
March 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28287861/association-of-skin-intrinsic-fluorescence-with-retinal-microvascular-complications-of-long-term-type-1-diabetes-in-the-wisconsin-epidemiologic-study-of-diabetic-retinopathy
#14
Barbara E K Klein, Kayla L Horak, John D Maynard, Kristine E Lee, Ronald Klein
OBJECTIVE: To determine the association between skin intrinsic fluorescence (SIF), a noninvasive measure of advanced glycation endproducts and oxidative stress in skin, and retinal microvascular complications of long duration type 1 diabetes, proliferative diabetic retinopathy (PDR) and macular edema. METHODS: A cross-sectional cohort study of persons with type 1 diabetes in the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR) who participated in a 32-year follow-up examination in 2012-2014...
March 13, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28287813/effect-of-consanguinity-on-low-birth-weight-a-meta-analysis
#15
REVIEW
Jalal Poorolajal, Pegah Ameri, Alireza Soltanian, Masoud Bahrami
BACKGROUND: Consanguinity (when couples share at least one common ancestor) is a public health issue with a variety of distributions and incidence rates worldwide. Several epidemiological studies have explored the association between consanguinity and low birth weight (LBW). However, the results are inconsistent. This meta-analysis aimed to explore the overall association between consanguineous marriage and LBW. METHODS: We searched PubMed, Web of Science, Scopus, ScienceDirect, and reference lists of articles up to May 2015...
March 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28286177/screening-for-novel-central-nervous-system-biomarkers-in-veterans-with-gulf-war-illness
#16
Mohamed B Abou-Donia, Lisa A Conboy, Efi Kokkotou, Eric Jacobson, Eman M Elmasry, Passent Elkafrawy, Megan Neely, Cameron R 'Dale' Bass, Kimberly Sullivan
Gulf War illness (GWI) is primarily diagnosed by symptom report; objective biomarkers are needed that distinguish those with GWI. Prior chemical exposures during deployment have been associated in epidemiologic studies with altered central nervous system functioning in veterans with GWI. Previous studies from our group have demonstrated the presence of autoantibodies to essential neuronal and glial proteins in patients with brain injury and autoantibodies have been identified as candidate objective markers that may distinguish GWI...
March 9, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/28285934/human-exposure-to-chemical-mixtures-challenges-for-the-integration-of-toxicology-with-epidemiology-data-in-risk-assessment
#17
REVIEW
Antonio F Hernández, Aristidis M Tsatsakis
Little is known about the potential adverse effects from longterm exposure to complex mixtures at low doses, close to health-based reference values. Traditional chemical-specific risk assessment based on animal testing may be insufficient and the lack of toxicological studies on chemical mixtures remains a major regulatory challenge. Hence, new methodologies on cumulative risk assessment are being developed but still present major limitations. Evaluation of chemical mixture effects requires an integrated and systematic approach and close collaboration across different scientific fields, particularly toxicology, epidemiology, exposure science, risk assessment and statistics for a proper integration of data from all these disciplines...
March 7, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28285784/pediatric-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis-in-the-united-states
#18
Derek Y Hsu, Joaquin Brieva, Nanette B Silverberg, Amy S Paller, Jonathan I Silverberg
BACKGROUND: Little is known about the epidemiology of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in children. OBJECTIVE: We sought to determine the morbidity, mortality, and comorbid health conditions of SJS and TEN in US children. METHODS: This was a cross-sectional study of the 2009 to 2012 Nationwide Inpatient Sample, which contains a representative 20% sample of all US hospitalizations. Sociodemographics, inflation-adjusted cost, length of stay, comorbidities, and mortality were analyzed using descriptive statistics and multivariate regression analyses...
March 9, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28285750/nerve-damage-in-young-patients-with-leprosy-diagnosed-in-an-endemic-area-of-the-brazilian-amazon-a-cross-sectional-study
#19
Sabrina Sampaio Bandeira, Carla Avelar Pires, Juarez Antonio Simões Quaresma
OBJECTIVE: To describe nerve damage and its association with clinical and epidemiologic characteristics in young patients with leprosy diagnosed in an endemic area of the Brazilian Amazon. STUDY DESIGN: All 45 patients with leprosy younger than 15 years of age and diagnosed at a health referral unit in northern Brazil were invited to participate in a cross-sectional, descriptive, analytical study. Subjects were submitted to a templated simple neurologic examination of the peripheral nerves and answered a structured questionnaire...
March 9, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28284713/air-quality-environmental-epidemiology-studies-are-unreliable
#20
S Stanley Young
Ever since the London Great Smog of 1952 is estimated to have killed over 4000 people, scientists have studied the relationship between air quality and acute mortality. There are many hundreds of papers examining the question. There is a serious statistical problem with most of these papers. If there are many questions under consideration, and there is no adjustment for multiple testing or multiple modeling, then unadjusted p-values are totally unreliable making claims unreliable. Our idea is to determine the statistical reliability of eight papers published in Environmental Health Perspectives that were used in meta-analysis papers appearing in Lancet and JAMA...
March 8, 2017: Regulatory Toxicology and Pharmacology: RTP
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