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https://www.readbyqxmd.com/read/29053158/prevalence-of-myeloma-precursor-state-monoclonal-gammopathy-of-undetermined-significance-in-12372-individuals-10-49-years-old-a-population-based-study-from-the-national-health-and-nutrition-examination-survey
#1
O Landgren, B I Graubard, S Kumar, R A Kyle, J A Katzmann, K Murata, R Costello, A Dispenzieri, N Caporaso, S Mailankody, N Korde, M Hultcrantz, T M Therneau, D R Larson, J R Cerhan, S V Rajkumar
We studied the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in younger individuals, age 10-49 years, using samples from the National Health and Nutritional Examination Survey (NHANES) III. NHANES prevalence rates were standardized to the 2000 US total population. Among 12 372 individuals (4073 blacks, 4146 Mexican-Americans, 3595 whites, and 558 others), MGUS was identified in 63 persons (0.34%, 95% CI 0.23-0.50). The prevalence of MGUS was significantly higher in blacks (0.88%, 95% CI 0...
October 20, 2017: Blood Cancer Journal
https://www.readbyqxmd.com/read/29050682/effect-of-exceptional-parental-longevity-and-lifestyle-factors-on-prevalence-of-cardiovascular-disease-in-offspring
#2
Sriram Gubbi, Elianna Schwartz, Jill Crandall, Joe Verghese, Roee Holtzer, Gil Atzmon, Rebecca Braunstein, Nir Barzilai, Sofiya Milman
Offspring of parents with exceptional longevity (OPEL) manifest lower prevalence of cardiovascular disease (CVD), but the role of lifestyle factors in this unique cohort is not known. Our study tested whether OPEL have lesser prevalence of CVD independent of lifestyle factors. Prevalence of CVD and CVD risk factors was assessed in a population of community-dwelling Ashkenazi Jewish adults aged 65 to 94 years. Participants included OPEL (n = 395), defined as having at least 1 parent living past the age of 95 years, and offspring of parents with usual survival (OPUS, n = 450), defined as having neither parent survive to 95 years...
September 18, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29050032/providing-personalised-nutrition-consumers-trust-and-preferences-regarding-sources-of-information-service-providers-and-regulators-and-communication-channels
#3
Rui Poínhos, Bruno M P M Oliveira, Ivo A van der Lans, Arnout R H Fischer, Aleksandra Berezowska, Audrey Rankin, Sharron Kuznesof, Barbara Stewart-Knox, Lynn J Frewer, Maria D V de Almeida
BACKGROUND/AIMS: Personalised nutrition has potential to revolutionise dietary health promotion if accepted by the general public. We studied trust and preferences regarding personalised nutrition services, how they influence intention to adopt these services, and cultural and social differences therein. METHODS: A total of 9,381 participants were quota-sampled to be representative of each of 9 EU countries (Germany, Greece, Ireland, Poland, Portugal, Spain, the Netherlands, the UK, and Norway) and surveyed by a questionnaire assessing their intention to adopt personalised nutrition, trust in service regulators and information sources, and preferences for service providers and information channels...
October 20, 2017: Public Health Genomics
https://www.readbyqxmd.com/read/29048714/high-genetic-risk-scores-for-impaired-insulin-secretory-capacity-doubles-the-risk-for-type-2-diabetes-in-asians-and-is-exacerbated-by-western-type-diets
#4
Da Sol Kim, Byoung Chul Kim, James W Daily, Sunmin Park
BACKGROUND: Asians have among the highest incidence of type 2 diabetes (T2DM) in the world, partly due to low β-cell function, causing them to rapidly develop T2DM when insulin resistant. This study tested the hypothesis that genetic polymorphisms are responsible for the low β-cell function and that dietary factors interact with the genes to exacerbate their risk of T2DM. METHODS: We selected 10 genetic variants of 5 genes involved in insulin secretion (CDKAL1, KCNQ1, IDE, HHEX, and ABCA1) from the genome-wide association studies to calculate the genetic risk scores (GRSs) in 8842 Korean adults in the Ansan/Ansung cohort in the Korean Genome Epidemiology Study...
September 5, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29048210/breastfeeding-challenges-and-the-preterm-mother-infant-dyad-a-conceptual-model
#5
Chantal Lau
Breastfeeding is an experience that only a mother and her infant(s) can share. Infants who can feed from the breast receive not only the best nutrition but also, due to the close physical contact between mother and child, it is the optimal nurturance they can receive from their mother. When breastfeeding is trouble free, maternal well-being is uniquely heightened. However, breastfeeding remains a challenge for many mother-infant dyads and more so for those whose infants are born prematurely. This article introduces a conceptual model of the breastfeeding challenges facing preterm mother-infant dyads...
October 19, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29046332/adipose-tissue-lpl-methylation-is-associated-with-triglyceride-concentrations-in-the-metabolic-syndrome
#6
Daniel Castellano-Castillo, Isabel Moreno-Indias, José Carlos Fernández-García, Juan Alcaide-Torres, Inmaculada Moreno-Santos, Luis Ocaña, Enrique Gluckman, Francisco Tinahones, María Isabel Queipo-Ortuño, Fernando Cardona
BACKGROUND: DNA methylation is one of the epigenetic mechanisms that regulate gene expression. DNA methylation may be modified by environmental and nutritional factors. Thus, epigenetics could potentially provide a mechanism to explain the etiology of metabolic disorders, such as metabolic syndrome (MetS). The aim of this study was to analyze the level of DNA methylation of several lipoprotein lipase (LPL)-promoter-CpG dinucleotides in a CpG island region and relate this to the gene and protein expression levels in human visceral adipose tissue (VAT) from individuals with and without MetS...
October 18, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29046327/time-trends-of-dietary-and-lifestyle-factors-and-their-potential-impact-on-diabetes-burden-in-china
#7
Yanping Li, Dong D Wang, Sylvia H Ley, Malik Vasanti, Annie Green Howard, Yuna He, Frank B Hu
OBJECTIVE: To examine the secular trends in risk factors, estimate their impact on type 2 diabetes burden from 1991 to 2011, and project trends in the next 20 years. RESEARCH DESIGN AND METHODS: Risk factor distributions were based on data from the China Health and Nutrition Survey 1991-2011. Diabetes cases attributable to all nonoptimal levels of each risk factor were estimated by applying the comparative risk assessment method. RESULTS: In 2011, high BMI was the leading individual attributable factor for diabetes cases in China responsible for 43...
October 18, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29046259/assessing-the-impact-of-quality-improvement-measures-on-catheter-related-blood-stream-infections-and-catheter-salvage-experience-from-a-national-intestinal-failure-unit
#8
A Bond, A Teubner, M Taylor, C Cawley, A Abraham, M Dibb, P R Chadwick, M Soop, G Carlson, S Lal
BACKGROUND & AIMS: Prevention of catheter related blood stream infections (CRBSI) and salvage of infected central venous catheters (CVC) are vital to maintaining long term venous access in patients needing home parenteral nutrition (HPN). It remains unclear as to whether patients are best trained for catheter care at home or in hospital or whether CRBSIs are lower if the patient self-cares for the CVC. Furthermore, there is minimal data on the longer term outcome following salvage of infected catheter and limited consensus on agreed protocols for catheter salvage...
October 10, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29046007/-dietary-recommendations-in-metabolic-vascular-syndrome
#9
Katharina Lechner, Nicole Erickson, Benjamin Lechner, Florian Horn
Cardiovascular disease is the number one cause of death globally. Poor diet constitutes a key factor in the initiation and progression of cardiovascular disease and has become the leading risk factor for disability and death worldwide. Therefore, addressing suboptimal nutrition is of key prognostic relevance in primary and secondary prevention of metabolic vascular syndrome.Metabolic vascular syndrome is a multidimensional network of acquired cardiometabolic risk factors closely related to insulin resistance (IR) and concomitant hyperinsulinemia...
October 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29044897/a-comparison-of-dietary-estimates-from-the-national-aboriginal-and-torres-strait-islander-health-survey-to-food-and-beverage-purchase-data
#10
Emma McMahon, Thomas Wycherley, Kerin O'Dea, Julie Brimblecombe
OBJECTIVE: We compared self-reported dietary intake from the very remote sample of the National Aboriginal and Torres Strait Islander Nutrition and Physical Activity Survey (VR-NATSINPAS; n=1,363) to one year of food and beverage purchases from 20 very remote Indigenous Australian communities (servicing ∼8,500 individuals). METHODS: Differences in food (% energy from food groups) and nutrients were analysed using t-test with unequal variance. RESULTS: Per-capita energy estimates were not significantly different between the surveys (899 MJ/person/day [95% confidence interval -152,1950] p=0...
October 18, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29044338/nutritional-profile-of-hemodialysis-patients-concerning-treatment-time
#11
Livia de Almeida Alvarenga, Bárbara Danelon Andrade, Michelle Andrade Moreira, Roberto de Paula Nascimento, Isabela Dariú Macedo, Aline Silva de Aguiar
INTRODUCTION: The mortality of the population with chronic kidney disease (CKD) on hemodialysis (HD) is very high and the protein-energy malnutrition stands out as one of the most common consequences in relation to this condition. OBJECTIVE: To evaluate the association between time of hemodialysis and nutritional parameters of patients. METHODS: It is a cross-sectional study with secondary data, developed of the University Hospital of the Federal University of Juiz de Fora (HU/UFJF)...
July 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29043569/nutritional-support-and-parenteral-nutrition-in-cancer-patients-an-expert-consensus-report
#12
REVIEW
J A Virizuela, M Camblor-Álvarez, L M Luengo-Pérez, E Grande, J Álvarez-Hernández, M J Sendrós-Madroño, P Jiménez-Fonseca, M Cervera-Peris, M J Ocón-Bretón
BACKGROUND: Malnutrition is a frequent medical problem of cancer patients that negatively impacts their quality of life. METHODS: A multidisciplinary group of experts in Medical Oncology, Pharmacy, and Nutrition convened to discuss the management of the nutritional support in cancer patients. RESULTS: Of the 18 questions addressed, 9 focused on nutritional support, 5 were related to parenteral nutrition (PN) and 4 about home PN (HPN). The panel of experts recommends using nutritional screening routinely, at diagnosis and throughout the disease course, for detecting the risk of malnutrition and, if it is positive, to perform a complete nutritional assessment, to diagnose malnutrition...
October 17, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29043487/the-differences-in-spirometry-predictive-equations-in-classifying-presence-and-degree-of-lung-function-impairment-which-suit-fits-the-best
#13
Marija Vukoja, Aleksandar Bokan, Gordana Vujasinovic, Ivan Kopitovic
PURPOSE: The aim of this study was to compare the differences between three most commonly used predictive equations (PE): ECCS (European Community of Coal and Steel), the third National Health and Nutrition Examination Survey (NHANES III), and GLI (Global Lung Initiative) in healthy individuals and when grading severity of lung function impairment in patients with obstructive lung diseases. METHODS: The study included 200 healthy volunteers and 200 patients with obstructive lung diseases at the Institute for Pulmonary Diseases of Vojvodina...
October 17, 2017: Lung
https://www.readbyqxmd.com/read/29043285/the-relationship-between-health-locus-of-control-and-health-behaviors-in-emergency-medicine-personnel
#14
Mansour Pourhoseinzadeh, Mahin Gheibizadeh, Mehrnaz Moradikalboland
BACKGROUND: Health locus of control defined as individual beliefs based on past experiences in health issues and having external or internal control over them, could affect health. Health locus of control plays a role in health behaviors. We aimed to investigate the relationship between health locus of control and health behavior in emergency medical personnel in Ahvaz during 2016. METHODS: This is a cross-sectional descriptive study, which began in August 2016 for a period of six months on 215 emergency medical personnel in Ahvaz who were selected randomly...
October 2017: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/29043250/canine-food-preference-assessment-of-animal-and-vegetable-ingredient-based-diets-using-single-pan-tests-and-behavioral-observation
#15
Meghan C Callon, Cara Cargo-Froom, Trevor J DeVries, Anna K Shoveller
Knowledge of canine food selection is critical for both the pet food industry and dog owners, since owners want quality foods that are palatable, while fulfilling their pet's nutritional requirements. There are two common methods for assessing canine food preference: the two-pan test and the one-pan test. Neither test fully accounts for the complexity of the canine feeding experience nor do they provide applicable representations of canine feeding behavior in the home. The objectives of this study were to (1) determine whether dogs display a preference for animal ingredient-based diets when compared with vegetable ingredient-based diets and (2) examine whether dogs experience neophobia when presented with a novel diet...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29043008/ancestors-dietary-patterns-and-environments-could-drive-positive-selection-in-genes-involved-in-micronutrient-metabolism-the-case-of-cofactor-transporters
#16
Silvia Parolo, Sébastien Lacroix, Jim Kaput, Marie-Pier Scott-Boyer
BACKGROUND: During evolution, humans colonized different ecological niches and adopted a variety of subsistence strategies that gave rise to diverse selective pressures acting across the genome. Environmentally induced selection of vitamin, mineral, or other cofactor transporters could influence micronutrient-requiring molecular reactions and contribute to inter-individual variability in response to foods and nutritional interventions. METHODS: A comprehensive list of genes coding for transporters of cofactors or their precursors was built using data mining procedures from the HGDP dataset and then explored to detect evidence of positive genetic selection...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/29042806/feeding-filaggrin-effects-of-l-histidine-supplementation-in-atopic-dermatitis
#17
Siao Pei Tan, Simon B Brown, Christopher Em Griffiths, Richard B Weller, Neil K Gibbs
Atopic dermatitis (AD), also known as eczema, is one of the most common chronic skin conditions worldwide, affecting up to 16% of children and 10% of adults. It is incurable and has significant psychosocial and economic impacts on the affected individuals. AD etiology has been linked to deficiencies in the skin barrier protein, filaggrin. In mammalian skin, l-histidine is rapidly incorporated into filaggrin. Subsequent filaggrin proteolysis releases l-histidine as an important natural moisturizing factor (NMF)...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29040716/dietary-carbohydrates-components-of-energy-balance-and-associated-health-outcomes
#18
Harry A Smith, Javier T Gonzalez, Dylan Thompson, James A Betts
The role of dietary carbohydrates in the development of obesity and associated metabolic dysfunction has recently been questioned. Within the last decade, the Scientific Advisory Committee on Nutrition carried out a comprehensive evaluation of the role of dietary carbohydrates in human health. The current review aims to complement and extend this report by providing specific consideration of the effects of the component parts of energy balance, their interactions, and their culmination on energy storage and health...
October 5, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29040554/frailty-syndrome-an-emerging-clinical-problem-in-the-everyday-management-of-clinical-arrhythmias-the-results-of-the-european-heart-rhythm-association-survey
#19
Stefano Fumagalli, Tatjana S Potpara, Torben Bjerregaard Larsen, Kristina H Haugaa, Dan Dobreanu, Alessandro Proclemer, Nikolaos Dagres
The age of patients presenting with complex arrhythmias is increasing. Frailty is a multifaceted syndrome characterized by an increased vulnerability to stressors and a decreased ability to maintain homeostasis. The prevalence of frailty is associated with age. The aims of this European Heart Rhythm Association (EHRA) EP Wire survey were to evaluate the proportion of patients with frailty and its influence on the clinical management of arrhythmias. A total of 41 centres-members of the EHRA Electrophysiology Research Network-in 14 European countries completed the web-based questionnaire in June 2017...
October 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29040542/high-adherence-to-the-mediterranean-diet-is-associated-with-cardiovascular-protection-in-higher-but-not-in-lower-socioeconomic-groups-prospective-findings-from-the-moli-sani-study
#20
Marialaura Bonaccio, Augusto Di Castelnuovo, George Pounis, Simona Costanzo, Mariarosaria Persichillo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Background: It is uncertain whether the cardiovascular benefits associated with Mediterranean diet (MD) may differ across socioeconomic groups. Methods: Prospective analysis on 18991 men and women aged ≥35 years from the general population of the Moli-sani cohort (Italy). Adherence to MD was appraised by the Mediterranean diet score (MDS). Household income (euros/year) and educational level were used as indicators of socioeconomic status. Hazard ratios (HR) were calculated by multivariable Cox proportional hazard models...
August 1, 2017: International Journal of Epidemiology
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