keyword
MENU ▼
Read by QxMD icon Read
search

minimal change lesion

keyword
https://www.readbyqxmd.com/read/28093934/efficacy-and-safety-of-oral-sildenafil-in-treatment-of-pediatric-head-and-neck-lymphatic-malformations
#1
Shengcai Wang, Jie Zhang, Wentong Ge, Yuanhu Liu, Yongli Guo, Yue Liu, Ning Wang, Yuzhu He, Jun Tai, Xin Ni
CONCLUSIONS: Low dose oral sildenafil citrate tablets are safe and effective to decrease the lesions volume in some LMs children, especially with macrocystic lesion or mixed type. OBJECTIVE: To evaluate the efficacy and safety of oral sildenafil in treatment of pediatric head and neck lymphatic malformations (LMs). SUBJECTS AND METHODS: In this open-label study, 21 children diagnosed with LMs were given oral sildenafil and stopped at week 24...
January 17, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28091849/dynamic-optical-absorption-characteristics-of-blood-after-slow-and-fast-heating
#2
Hao Jia, Bin Chen, Dong Li
Laser treatment is the most effective therapy in dermatology for vascular skin disorders, such as port-wine stains (PWS). Changes in heat-induced absorbance in blood must be determined for accurate numerical simulation and implementation of multi-pulse laser therapy for treatment of PWS. Thermally induced absorbance changes in hemoglobin in blood were compared in vitro between slow water bath heating and fast heating irradiated by using sub-millisecond Nd:YAG laser. Blood composition at different temperatures was calculated by comparing blood absorption spectra with those of pure HbO2, Hb, and metHb at room temperature...
January 13, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28089791/supplement-ct-guided-microcoil-placement-for-localising-ggo-lesions-at-blind-areas-of-the-conventional-hook-wire-technique
#3
Tao Zuo, Shunbin Shi, Long Wang, Zhe Shi, Chenyang Dai, Chuanyi Li, Xiaogang Zhao, Zhengyi Ni, Ke Fei, Chang Chen
BACKGROUND: In the conventional hook-wire technique of pulmonary nodular localisations there are several "blind areas", including the mediastinum-vicinity region, interlobar fissure-neighbouring areas and scapulae-shadowed areas. The present study aims to summarise the experiences of CT-guided microcoil placement as an alternative method for localising pulmonary ground-glass opacity (GGO) lesions before thoracoscopic wedge resections. METHODS: Sixteen GGO lesions at "blind areas" in 16 patients were localised with platinum-fibered microcoils under CT assistance before undergoing video-assisted thoracoscopic surgical resections...
November 19, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28089478/the-clinical-course-of-minimal-change-nephrotic-syndrome-with-onset-in-adulthood-or-late-adolescence-a-case-series
#4
Rutger J Maas, Jeroen K Deegens, Johan R Beukhof, Louis J Reichert, Marc A Ten Dam, Jaap J Beutler, A Warmold L van den Wall Bake, Pieter L Rensma, Constantijn J Konings, Daniel A Geerse, Geert W Feith, Willi H Van Kuijk, Jack F Wetzels
BACKGROUND: Few studies have examined the treatment and outcome of adult-onset minimal change nephrotic syndrome (MCNS). We retrospectively studied 125 patients who had MCNS with onset in either adulthood or late adolescence. Presenting characteristics, duration of initial treatment and response to treatment, relapse patterns, complications, and long-term outcome were studied. STUDY DESIGN: Case series. SETTING & PARTICIPANTS: Patients with new-onset nephrotic syndrome 16 years or older and a histologic diagnosis of MCNS in 1985 to 2011 were identified from pathology records of 10 participating centers...
January 12, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28079267/estimating-4d-cbct-from-prior-information-and-extremely-limited-angle-projections-using-structural-pca-and-weighted-free-form-deformation-for-lung-radiotherapy
#5
Wendy Harris, You Zhang, Fang-Fang Yin, Lei Ren
PURPOSE: To investigate the feasibility of using structural-based principal component analysis (PCA) motion-modeling and weighted free-form deformation to estimate on-board 4D-CBCT using prior information and extremely limited angle projections for potential 4D target verification of lung radiotherapy. METHODS: A technique for lung 4D-CBCT reconstruction has been previously developed using a deformation field map (DFM)-based strategy. In the previous method, each phase of the 4D-CBCT was generated by deforming a prior CT volume...
January 12, 2017: Medical Physics
https://www.readbyqxmd.com/read/28066671/current-advances-of-endobronchial-ultrasonography-in-the-diagnosis-and-staging-of-lung-cancer
#6
REVIEW
Chao-Chi Ho, Ching-Kai Lin, Ching-Yao Yang, Lih-Yu Chang, Shu-Yung Lin, Chong-Jen Yu
The diagnosis and staging of patients with lung cancer has relied on tissue sampling. Endobronchial ultrasound (EBUS) is a minimally invasive procedure for the rapid and safe acquisition of tissue and can be done easily and repeatedly. EBUS transbronchial needle aspiration (TBNA) is now the standard for diagnosis of mediastinal and hilar lymphadenopathy and should be considered in patients who have a high probability of lymph node metastases without systemic involvement. EBUS also provides guidance for biopsy of peripheral lung lesions...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28063762/isolated-acetabuloplasty-and-labral-repair-for-combined-type-femoroacetabular-impingement-are-we-doing-too-much
#7
Vehniah K Tjong, Mustafa M Gombera, Cynthia A Kahlenberg, Ronak M Patel, Brian Han, Prashant Deshmane, Michael A Terry
PURPOSE: To evaluate patient outcomes after isolated arthroscopic volumetric acetabular osteoplasty and labral repair for the treatment of patients with combined femoroacetabular impingement (FAI) lesions. METHODS: A review of a prospectively collected registry identified 86 patients (106 hips) with an average age of 38.1 years (range, 17-59 years) with combined-type FAI that underwent isolated acetabular osteoplasty and labral repair. Preoperative α-angle, degree of radiographic degenerative changes, and presence of a crossover sign were recorded...
January 4, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28057011/functional-and-radiological-outcomes-of-a-minimally-invasive-surgical-approach-to-monostotic-fibrous-dysplasia
#8
Mamer S Rosario, Katsuhiro Hayashi, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Yuta Taniguchi, Hiroyuki Tsuchiya
BACKGROUND: Reports showing high recurrence rates for intralesional curettage and bone grafting have made the current treatment principle for fibrous dysplasia controversial. This study aimed to report the postoperative clinical outcomes from three minimally invasive surgical strategies we use for monostotic fibrous dysplasia (MFD). PATIENTS AND METHODS: Twelve patients with MFD presenting with no pathologic fracture or deformity and treated with one of three surgical strategies-plain open biopsy, plain alpha-tricalcium phosphate (ATP) reconstruction, and prophylactic bridge plating-were included...
January 5, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28047816/su-g-jep3-04-estimating-4d-cbct-from-prior-information-and-extremely-limited-angle-projections-using-structural-pca-and-weighted-free-form-deformation
#9
W Harris, F Yin, Y Zhang, L Ren
PURPOSE: To investigate the feasibility of using structure-based principal component analysis (PCA) motion-modeling and weighted free-form deformation to estimate on-board 4D-CBCT using prior information and extremely limited angle projections for potential 4D target verification of lung radiotherapy. METHODS: A technique for lung 4D-CBCT reconstruction has been previously developed using a deformation field map (DFM)-based strategy. In the previous method, each phase of the 4D-CBCT was generated by deforming a prior CT volume...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047142/we-ab-bra-04-investigation-of-mri-derived-thermal-dose-models
#10
C MacLellan, D Fuentes, H Espinoza, S Prabhu, G Rao, J Weinberg, R Stafford
PURPOSE: To develop and investigate a novel thermal dose model methodology using MR temperature imaging (MRTI) and post-treatment MRI changes as a surrogate of tissue damage in clinical laser ablation of the brain. METHODS: Post-treatment contrast enhanced T1-weighted images were registered to MRTI acquired during two MR-guided thermal ablation procedures. The non-enhancing central region and hyperintense ring of vascular disruption characteristic of the thermal lesion were segmented manually and resampled into the 2D geometry of the MRTI...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044312/optimization-of-contrast-enhanced-breast-imaging-analysis-using-a-cascaded-linear-system-model
#11
Yue-Houng Hu, David A Scaduto, Wei Zhao
PURPOSE: Contrast-enhanced (CE) breast imaging involves the injection contrast agents (i.e., iodine) to increase conspicuity of malignant lesions. CE imaging may be used in conjunction with digital mammography (DM) or digital breast tomosynthesis (DBT) and has shown promise in improving diagnostic specificity. Both CE-DM and CE-DBT techniques require optimization as clinical diagnostic tools. Physical factors including x-ray spectra, subtraction technique, and the signal from iodine contrast, must be considered to provide the greatest object detectability and image quality...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28039859/cholesterol-crystallisation-in-human-atherosclerosis-is-triggered-in-smooth-muscle-cells-during-the-transition-from-fatty-streak-to-fibroatheroma
#12
Benoît Ho-Tin-Noé, Sophie Vo, Richard Bayles, Stephen Ferrière, Hayette Ladjal, Sondes Toumi, Catherine Deschildre, Véronique Ollivier, Jean-Baptiste Michel
Recent studies have shown that in addition to being major constituents of the atheromatous core, solid cholesterol crystals (CCs) promote atherosclerotic lesion development and rupture by causing mechanical damage and exerting cytotoxic and pro-inflammatory effects. These findings suggest that targeting CCs might represent a therapeutic strategy for plaque stabilisation. However, little is known about how cholesterol crystallisation is initiated in human atherothrombotic disease. Here, we investigated these mechanisms...
December 31, 2016: Journal of Pathology
https://www.readbyqxmd.com/read/28031085/percutaneous-removal-of-benign-breast-lesions-with-an-ultrasound-guided-vacuum-assisted-system-influence-factors-in-the-hematoma-formation
#13
Hui-Ping Huo, Wen-Bo Wan, Zhi-Li Wang, Hong-Fei Li, Jun-Lai Li
Objective To explore the influence factors in hematoma formation after removing benign breast lesions with an ultrasound-guided vacuum-assisted system.Methods A total of 232 females with 312 benign breast masses received excisional biopsy with ultrasound- guided vacuum-assisted system. The pathology of patients, Results of hematoma development and outcome, influence factors for hematoma occurrence (nodule size, nodule location, number of nodule, breast shape, menstrual period, efficacy time of bandage, and application of hemostatic agents during the procedure) were recorded...
March 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28024850/volume-of-subclinical-embolic-infarct-correlates-to-long-term-cognitive-changes-after-carotid-revascularization
#14
Wei Zhou, Brittanie D Baughman, Salil Soman, Max Wintermark, Laura C Lazzeroni, Elizabeth Hitchner, Jyoti Bhat, Allyson Rosen
OBJECTIVE: Carotid intervention is safe and effective in stroke prevention in appropriately selected patients. Despite minimal neurologic complications, procedure-related subclinical microemboli are common and their cognitive effects are largely unknown. In this prospective longitudinal study, we sought to determine long-term cognitive effects of embolic infarcts. METHODS: The study recruited 119 patients including 46% symptomatic patients who underwent carotid revascularization...
December 23, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28009766/urgent-bypass-surgery-following-failed-endovascular-treatment-in-acute-symptomatic-stroke-patient-with-mca-occlusion
#15
Chang Yeob Lee, Chang Hyun Kim, Chang-Young Lee, Sung-Il Sohn, Jeong-Ho Hong
INTRODUCTION: Although the benefits of extracranial-intracranial bypass surgery remain controversial, there is some surgical rationale for the augmentation of cerebral blood flow in cases of acute ischemic stroke with hemodynamic instability. CASE REPORT: We report a case of a 62-year-old woman who suddenly developed right hemiplegia and global aphasia. Initial magnetic resonance imaging and magnetic resonance angiography revealed a small acute ischemic lesion in left parietal lobe with occlusion at the left middle cerebral artery...
January 2017: Neurologist
https://www.readbyqxmd.com/read/28005510/case-237-renal-cell-carcinoma-with-osseous-metaplasia
#16
Billy Ming Hei Lai, Solomon Yig Joon Ka, Wai Kuen Kan, Man Wah Lam, Tang Fei Lee, Yun Hoi Lui, Jennifer Lai San Khoo
History A 47-year-old man presented with palpitations and decreased exercise tolerance. A peripheral blood smear revealed anemia, thrombocytopenia, and blast cells, and a diagnosis of acute myeloid leukemia was made. Immunohistochemistry revealed positivity for cluster of differentiation (or CD) markers, which have been reported to be associated with an increased risk of extramedullary leukemic involvement. Thus, contrast material-enhanced computed tomography (CT) of the thorax, abdomen, and pelvis was requested to enable exclusion of any extramedullary extension of leukemia...
January 2017: Radiology
https://www.readbyqxmd.com/read/27993756/change-in-lumen-eccentricity-and-asymmetry-after-treatment-with-absorb-bioresorbable-vascular-scaffolds-in-the-absorb-cohort-b-trial-a-five-year-serial-optical-coherence-tomography-imaging-study
#17
Pannipa Suwannasom, Yohei Sotomi, Taku Asano, Jaryl Ng Chen Koon, Hiroki Tateishi, Yaping Zeng, Erhan Tenekecioglu, Joanna J Wykrzykowska, Nicolas Foin, Robert J de Winter, John A Ormiston, Patrick W Serruys, Yoshinobu Onuma
AIMS: To investigate long-term changes in lumen eccentricity and asymmetry at 5 years after implantation of the bioresorbable vascular scaffold (BVS). METHODS AND RESULTS: Out of 101 patients from Absorb cohort B trial, 28 patients(29 lesions) with serial Optical Coherence Tomography(OCT) examination at 4 different time points(Cohort B1: post-procedure,6 months, 2, and 5 years[n=13]; Cohort B2:post-procedure,1, 3, and 5 years[n=16]) were evaluated. The longitudinal variance in lumen diameter was assessed by asymmetry index(AI)...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27989886/intracoronary-imaging-cholesterol-efflux-and-transcriptomes-after-intensive-statin-treatment-the-yellow-ii-study
#18
Annapoorna S Kini, Yuliya Vengrenyuk, Khader Shameer, Akiko Maehara, Meerarani Purushothaman, Takahiro Yoshimura, Mitsuaki Matsumura, Melissa Aquino, Nezam Haider, Kipp W Johnson, Ben Readhead, Brian A Kidd, Jonathan E Feig, Prakash Krishnan, Joseph Sweeny, Milind Mahajan, Pedro Moreno, Roxana Mehran, Jason C Kovacic, Usman Baber, Joel T Dudley, Jagat Narula, Samin Sharma
BACKGROUND: Despite the extensive evidence for the beneficial effects of statins on clinical outcomes, the mechanisms underlying these effects in remain elusive. OBJECTIVES: To assess the changes in plaque morphology by intravascular imaging with a comprehensive evaluation of cholesterol efflux capacity (CEC) and peripheral blood mononuclear cells (PBMC) transcriptomics in patients receiving high-dose statin therapy. METHODS: In a prospective study, 85 patients with stable multivessel coronary artery disease underwent percutaneous coronary intervention for a culprit lesion followed by intracoronary multi-modality imaging including optical coherence tomography (OCT) of an obstructive non-culprit lesion (NCL)...
October 27, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27982764/spinal-cord-hemangioblastomas-significance-of-intraoperative-neurophysiological-monitoring-for-resection-and-long-term-outcome
#19
Sebastian Siller, Andrea Szelényi, Lisa Herlitz, Joerg Christian Tonn, Stefan Zausinger
OBJECTIVE Spinal cord hemangioblastomas are rare benign tumors developing either sporadically or as part of von Hippel-Lindau (VHL) disease. Generally, resection is the treatment of choice. However, the significance of intraoperative neurophysiological monitoring (IONM) for resection and postoperative outcome is still controversial. The authors analyzed the surgical and clinical courses of patients who had undergone resection of spinal cord hemangioblastoma, with special attention to preoperative imaging, the use of IONM, and short- and long-term outcomes...
December 16, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27942722/a-period-of-controlled-elevation-of-iop-cei-produces-the-specific-gene-expression-responses-and-focal-injury-pattern-of-experimental-rat-glaucoma
#20
John C Morrison, William O Cepurna, Shandiz Tehrani, Tiffany E Choe, Hari Jayaram, Diana C Lozano, Brad Fortune, Elaine C Johnson
Purpose: We determine if several hours of controlled elevation of IOP (CEI) will produce the optic nerve head (ONH) gene expression changes and optic nerve (ON) damage pattern associated with early experimental glaucoma in rats. Methods: The anterior chambers of anesthetized rats were cannulated and connected to a reservoir to elevate IOP. Physiologic parameters were monitored. Following CEI at various recovery times, ON cross-sections were graded for axonal injury...
December 1, 2016: Investigative Ophthalmology & Visual Science
keyword
keyword
97348
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"