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https://www.readbyqxmd.com/read/29328519/surface-modification-using-the-biomimetic-method-in-alumina-zirconia-porous-ceramics-obtained-by-the-replica-method
#1
André D R Silva, Willian R Rigoli, Denise Osiro, Daphne C R Mello, Luana M R Vasconcellos, Anderson O Lobo, Eliria M J A Pallone
The modification of biomaterials approved by the Food and Drug Administration could be an alternative to reduce the period of use in humans. Porous bioceramics are widely used as support structures for bone formation and repair. This composite has essential characteristics for an implant, including good mechanical properties, high chemical stability, biocompatibility and adequate aesthetic appearance. Here, three-dimensional porous scaffolds of Al2 O3 containing 5% by volume of ZrO2 were produced by the replica method...
January 12, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29316208/effect-of-bone-sialoprotein-coated-three-dimensional-printed-calcium-phosphate-scaffolds-on-primary-human-osteoblasts
#2
Anja Klein, Andreas Baranowski, Ulrike Ritz, Hermann Götz, Sascha Heinemann, Stefan Mattyasovszky, Pol M Rommens, Alexander Hofmann
The combination of the two techniques of rapid prototyping 3D-plotting and bioactive surface functionalization is presented, with emphasis on the in vitro effect of Bone Sialoprotein (BSP) on primary human osteoblasts (hOBs). Our primary objective was to demonstrate the BSP influence on the expression of distinctive osteoblast markers in hOBs. Secondary objectives included examinations of the scaffolds' surface and the stability of BSP-coating as well as investigations of cell viability and proliferation. 3D-plotted calcium phosphate cement (CPC) scaffolds were coated with BSP via physisorption...
January 9, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29238285/generation-of-an-infectious-clone-of-a-new-korean-isolate-of-apple-chlorotic-leaf-spot-virus-driven-by-dual-35s-and-t7-promoters-in-a-versatile-binary-vector
#3
Ik-Hyun Kim, Jae-Yeong Han, In-Sook Cho, HyeKyoung Ju, Jae Sun Moon, Eun-Young Seo, Hong Gi Kim, John Hammond, Hyoun-Sub Lim
The full-length sequence of a new isolate of Apple chlorotic leaf spot virus (ACLSV) from Korea was divergent, but most closely related to the Japanese isolate A4, at 84% nucleotide identity. The full-length cDNA of the Korean isolate of ACLSV was cloned into a binary vector downstream of the bacteriophage T7 RNA promoter and the Cauliflower mosaic virus 35S promoter. Chenopodium quinoa was successfully infected using in vitro transcripts synthesized using the T7 promoter, detected at 20 days post inoculation (dpi), but did not produce obvious symptoms...
December 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/29222687/chrysophyllum-cainito-apple-star-a-fruit-with-gastroprotective-activity-in-experimental-ulcer-models
#4
Roseane Leandra da Rosa, Camila Leandra de Almeida, Lincon Bordigon Somensi, Thaise Boeing, Luisa Nathália Bolda Mariano, Clarissa de Medeiros Amorim Krueger, Priscila de Souza, Valdir Cechinel Filho, Luisa Mota da Silva, Sérgio Faloni de Andrade
The gastroprotective potential of the methanolic extracts from peels (MEPe), seeds (MESe) and pulp (MEPu) of Chrysophyllum cainito L. (Sapotaceae) fruits was evaluated in mice using ethanol/HCl- and indomethacin-induced ulcer, as well as the antiulcer effect of the juice and flour from this fruit. The lowest oral gastroprotective dose of MEPe, MESe and MEPu against ethanol/HCl was 3, 3 and 10 mg/kg, respectively. Moreover, all extracts increased mucin secretion at 176, 198 and 193%. Intraperitoneal administration of MEPe (0...
December 8, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/29218858/in-vitro-and-in-vivo-study-of-commercial-calcium-phosphate-cement-hydroset%C3%A2
#5
Niall W Kent, Gordon Blunn, Natalia Karpukhina, Graham Davis, Roberta Ferro de Godoy, Rory M Wilson, Melanie Coathup, Lyris Onwordi, Wen Yu Quak, Robert Hill
The commercial calcium phosphate cement, HydroSet™, was investigated in vitro, studying phase formation, compressive strength and setting time, followed by an ovine in vivo study to measure osseointegration, bone apposition and bone-to-graft contact. The X-ray diffraction and 31 P Magic Angle Spinning Nuclear Magnetic Resonance (MAS NMR) results showed the initial formation of octacalcium phosphate and hydroxyapatite at one hour. Over 7 days the octacalcium phosphate transformed to apatite, which was the only crystalline phase of the cement at 28 days...
January 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29218856/preparation-of-fluoride-loaded-microcapsules-for-anticariogenic-bacterial-growth-using-a-coaxial-ultrasonic-atomizer
#6
Hae-Won Choi, Seung-Hoon Um, Sang-Hoon Rhee
A new method to deliver fluoride using biodegradable poly(lactic-co-glycolic acid) microcapsules to suppress cariogenic bacterial growth during orthodontic treatment was investigated. A coaxial ultrasonic atomizer was used to encapsulate KF solution into microcapsules. The orthodontic adhesive resin disk containing fluoride loaded microcapsules (DFLM) was prepared by LED light curing. The microstructure of microcapsules, successful loading of KF, fracture strength, and shear bonding strength were assessed by FE-SEM, confocal laser scanning microscope, and general purpose testing machine, respectively...
January 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29193687/in-vitro-and-in-vivo-biological-characterization-of-poly-lactic-acid-fiber-scaffolds-synthesized-by-air-jet-spinning
#7
Marco Vladimir Granados-Hernández, Janeth Serrano-Bello, Juan José Montesinos, Carlos Alvarez-Gayosso, Luis Alberto Medina-Velázquez, Octavio Alvarez-Fregoso, Marco Antonio Alvarez-Perez
Poly(lactic acid) (PLA) is one of the most promising renewable and biodegradable polymers for mimic extracellular matrix for tissue engineering applications. In this work, PLA spun membrane scaffold were successfully prepared by air jet spinning technology. Morphology, mechanical properties, in vitro biocompatibility, and in vitro and in vivo degradation of PLA fibrous scaffold were characterized by X-ray diffraction, Fourier Transform Infrared, and scanning electron microscope (SEM). Morphological results assessed by SEM analyses indicated that PLA scaffolds possessed an average fiber diameter of approximately 0...
November 30, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29187344/one-drop-mobile-on-iphone-and-apple-watch-an-evaluation-of-hba1c-improvement-associated-with-tracking-self-care
#8
Chandra Y Osborn, Joost R van Ginkel, David G Marrero, David Rodbard, Brian Huddleston, Jeff Dachis
BACKGROUND: The One Drop | Mobile app supports manual and passive (via HealthKit and One Drop's glucose meter) tracking of self-care and glycated hemoglobin A1c (HbA1c). OBJECTIVE: We assessed the HbA1c change of a sample of people with type 1 diabetes (T1D) or type 2 diabetes (T2D) using the One Drop | Mobile app on iPhone and Apple Watch, and tested relationships between self-care tracking with the app and HbA1c change. METHODS: In June 2017, we identified people with diabetes using the One Drop | Mobile app on iPhone and Apple Watch who entered two HbA1c measurements in the app 60 to 365 days apart...
November 29, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29178263/characterizing-the-free-volume-of-ultrahigh-molecular-weight-polyethylene-to-predict-diffusion-coefficients-in-orthopedic-liners
#9
Kyle B Ludwig, Vaishnavi Chandrasekar, David M Saylor, Douglas W Van Citters, Steven D Reinitz, Christopher Forrey, Martin K McDermott, Samanthi Wickramasekara, Dustin W Janes
Liners used in orthopedic devices are often made from ultrahigh molecular weight polyethylene (UHMWPE). A general predictive capability for transport coefficients of small molecules in UHMWPE does not exist, making it difficult to assess properties associated with leaching or uptake of small molecules. To address this gap, we describe here how a form of the Vrentas-Duda free volume model can be used to predict upper-bound diffusion coefficients (D) of arbitrary molecules within UHMWPE on the basis of their size and shape...
November 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29149190/improved-capture-of-drosophila-suzukii-by-a-trap-baited-with-two-attractants-in-the-same-device
#10
Rodrigo Lasa, Eduardo Tadeo, Ricardo A Toledo-Hérnandez, Lino Carmona, Itzel Lima, Trevor Williams
The improvement of trap-lure combinations is an important part of integrated pest management programs that involve monitoring pests for timely insecticide applications, or for their use in control strategies such as mass trapping or bait stations. In this study improvements in the capture of Drosophila suzukii were not observed following the inclusion of different color stimuli with respect to a red-black stripe cup trap. This red-black stripe trap with a hemispherical dome-shaped lid had a significantly improved physical retention of flies compared to traps fitted with a flat lid...
2017: PloS One
https://www.readbyqxmd.com/read/29148054/transcriptome-analysis-unravels-an-ethylene-response-factor-involved-in-regulating-fruit-ripening-in-pear
#11
Ping-Ping Hao, Guo-Ming Wang, Hai-Yan Cheng, Ya-Qi Ke, Kai-Jie Qi, Chao Gu, Shao-Ling Zhang
Ethylene response factor (ERF) has been widely studied in regulating fruit ripening in tomato, apple, banana and kiwifruit, but little is known in pear. In this study 1-methylcyclopropene (1-MCP) treatment, an inhibitor of ethylene perception, was conducted at approximately 30 days before harvest to delay fruit ripening in a climacteric white pear cultivar Yali. Transcriptome libraries were constructed and sequenced in pre-ripening, ripening, and 1-MCP treated fruits. Data analysis showed that 73 candidate genes related to fruit ripening were induced by 1-MCP, among which two were positively related, namely 1-aminocyclopropane-1-carboxyla oxidase and an ERF gene (designated as ACO54 and ERF24)...
November 16, 2017: Physiologia Plantarum
https://www.readbyqxmd.com/read/29136835/design-and-construction-of-an-injection-port-for-coupling-stir-bar-sorptive-extraction-with-ion-mobility-spectrometry
#12
Mohammad T Jafari, Mohammad R Rezayat, Mehdi Mossaddegh
An appropriate injection port was designed and constructed for direct analysis of stir-bar sorptive extractions using an ion mobility spectrometry (IMS). The novel design of the port offers great simplicity in use, high sensitivity, and high thermal and mechanical stability. The sol-gel technique was applied to prepare polydimethylsiloxane absorbent on a stir-bar. The parameters affecting extraction efficiency including stirring rate, extraction temperature, extraction time, salt addition and desorption temperature were optimized...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29106034/evaluation-of-central-venous-catheters-coated-with-a-noble-metal-alloy-a-randomized-clinical-pilot-study-of-coating-durability-performance-and-tolerability
#13
Gunilla Björling, Dorota Johansson, Linda Bergström, Anton Strekalovsky, Javier Sanchez, Claes Frostell, Sigridur Kalman
The use of Central Venous Catheters (CVCs) commonly results in complications. Coatings with silver or metal alloys can reduce the risk associated with the use of CVC. We have evaluated the durability of a noble metal coated CVC (the Bactiguard Infectious Protection, BIP CVC) and compared with an uncoated CVC for clinical tolerability (Adverse Events, AEs) and performance, in order to create a baseline for a large future study. Patients undergoing major surgery, randomised at a 2:1 ratio to BIP CVC (n = 22) or standard CVC (n = 12), were catheterized 9 - 12 days, respectively...
November 6, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29068210/direct-conversion-of-co2-to-%C3%AE-farnesene-using-metabolically-engineered-synechococcus-elongatus-pcc-7942
#14
Hyun Jeong Lee, Jiwon Lee, Sun-Mi Lee, Youngsoon Um, Yunje Kim, Sang Jun Sim, Jong-Il Choi, Han Min Woo
Direct conversion of carbon dioxide (CO2) to value-added chemicals by engineering of cyanobacteria has received attention as a sustainable strategy in food and chemical industries. Herein, Synechococcus elongatus PCC 7942, a model cyanobacterium, was engineered to produce α-farnesene from CO2. Due to the lack of farnesene synthase (FS) activity in the wild-type cyanobacterium, we metabolically engineered S. elongatus PCC 7942 to express heterologous FS from either Norway spruce or apple fruit, resulting in detectable peaks of α-farnesene...
October 25, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29065223/influence-of-polysaccharide-based-edible-coatings-as-carriers-of-prebiotic-fibers-on-quality-attributes-of-ready-to-eat-fresh-blueberries
#15
María V Alvarez, Alejandra G Ponce, María R Moreira
BACKGROUND: Little information is available regarding the effect of dietary fibers added into edible coatings on quality attributes of ready-to-eat fruits. The aim of this study was to evaluate the effects of sodium alginate (AL) and chitosan (CH) edible coatings enriched with four different dietary fibers (apple fiber, orange fiber, inulin and oligofructose) on microbiological, nutritional, physicochemical and sensorial properties of ready-to-eat fresh blueberries stored for 18 days at 5 °C...
October 24, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29038553/a-comparison-of-passive-and-active-estimates-of-sleep-in-a-cohort-with-schizophrenia
#16
Patrick Staples, John Torous, Ian Barnett, Kenzie Carlson, Luis Sandoval, Matcheri Keshavan, Jukka-Pekka Onnela
Sleep abnormalities are considered an important feature of schizophrenia, yet convenient and reliable sleep monitoring remains a challenge. Smartphones offer a novel solution to capture both self-reported and objective measures of sleep in schizophrenia. In this three-month observational study, 17 subjects with a diagnosis of schizophrenia currently in treatment downloaded Beiwe, a platform for digital phenotyping, on their personal Apple or Android smartphones. Subjects were given tri-weekly ecological momentary assessments (EMAs) on their own smartphones, and passive data including accelerometer, GPS, screen use, and anonymized call and text message logs was continuously collected...
October 16, 2017: NPJ Schizophrenia
https://www.readbyqxmd.com/read/29036594/impaired-defense-reactions-in-apple-replant-disease-affected-roots-of-malus-domestica-m26
#17
Stefan Weiß, Benye Liu, Dennis Reckwell, Ludger Beerhues, Traud Winkelmann
A soil- and site-dependent complex of diverse microbial populations causes apple replant disease (ARD), which leads to economic losses for tree nurseries and apple producers due to reduced plant growth and diminished fruit yields. Soil fumigation has been widely used to mitigate ARD, but the application of these chemicals is restricted in the European Union. Hence, other counteractions have to be developed. Genomics-based breeding may be used to select ARD-tolerant genotypes; however, molecular responses of ARD are not well understood...
September 19, 2017: Tree Physiology
https://www.readbyqxmd.com/read/29031009/fabrication-of-biodegradable-foams-for-deep-tissue-negative-pressure-treatments
#18
Harleigh J Warner, William D Wagner
Devices for negative pressure wound therapy (NPWT) rely on compressible foams operating at the tissue-device interface. Clinically used foams are nonabsorbable and if used on deep wounds or left in place for an extended period of time, excessive cell ingrowth and formation of granulation tissue into the foam may require a surgical procedure to remove the foam. Foams with fast degradation and with low immunogenicity and fibrotic response are required. Foams composed of combinations of poly(lactide-co-glycolide) (PLGA), poly(lactide-co-caprolactone) (PLCL), and polycaprolactone (PCL) were created by combined salt leaching and solvent displacement protocols...
October 14, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28985142/sour-cherries-but-not-apples-added-to-the-regular-diet-decrease-resting-and-fmlp-stimulated-chemiluminescence-of-fasting-whole-blood-in-healthy-subjects
#19
Piotr Bialasiewicz, Anna Prymont-Przyminska, Anna Zwolinska, Agata Sarniak, Anna Wlodarczyk, Maciej Krol, Jaroslaw Markowski, Krzysztof P Rutkowski, Dariusz Nowak
OBJECTIVE: Berry fruits rich in anthocyanins have antioxidant and anti-inflammatory properties. Blood phagocytes are an important source of oxidants that contribute to inflammatory response and oxidative stress. We examined the effect of sour cherry consumption on luminol-enhanced whole blood chemiluminescence (LBCL) reflecting oxidants generation by circulating phagocytes in healthy subjects. METHODS: Thirty-four and 29 healthy subjects (on a regular diet) consumed 500 g of sour cherries containing 346...
October 6, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28977167/11%C3%AE-hydroxysteroid-dehydrogenase-type-ii-activity-is-affected-by-grapefruit-juice-and-intense-muscular-work
#20
Christopher Kargl, Mohammad Arshad, Fahad Salman, Regina C Schurman, Pedro Del Corral
OBJECTIVE: The enzymatic activity of 11β-hydroxysteroid dehydrogenase-2 (11β-HSD2) is key to protecting mineral corticoid receptors from cortisol and has been implicated in blood pressure regulation. Grapefruit juice (GFJ) and acidity are thought to inhibit this enzyme in vitro. This study examines the effect of GFJ and intense exercise on 11β-HSD2 enzyme activity in vivo. SUBJECTS AND METHODS: Eighteen subjects ingested GFJ or apple juice (CON) on separate days prior to reporting to the laboratory in a randomized order...
September 18, 2017: Archives of Endocrinology and Metabolism
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