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https://www.readbyqxmd.com/read/28527397/mri-surveillance-for-women-with-dense-breasts-and-a-previous-breast-cancer-and-or-high-risk-lesion
#1
Michelle Nadler, Hyder Al-Attar, Ellen Warner, Anne L Martel, Sharmila Balasingham, Liying Zhang, Joseph H Lipton, Belinda Curpen
BACKGROUND: The role of surveillance breast MRI for women with mammographically dense breasts, a personal history of breast cancer (BC), atypical hyperplasia (AH), or lobular carcinoma in situ (LCIS) is unclear. We estimated the performance of annual surveillance MRI in women with a combination of these risk factors. METHODS: We performed a retrospective review of the clinical, radiological, and pathological parameters of women who received annual concurrent surveillance breast MRI and mammography between 04/2013 and 12/2015 and fulfilled all of the following criteria: 1) age <70; 2) prior diagnosis of AH, LCIS or BC; 3) heterogeneously or extremely dense breast(s); and 4) did not qualify for our provincial breast MRI high risk screening program...
May 17, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28527372/dreams-deferred-contextualizing-the-health-and-psychosocial-needs-of-undocumented-asian-and-pacific-islander-young-adults-in-northern-california
#2
May Sudhinaraset, Irving Ling, Tu My To, Jason Melo, Thu Quach
There are currently 1.5 million undocumented Asians and Pacific Islanders (APIs) in the US. Undocumented API young adults, in particular, come of age in a challenging political and social climate, but little is known about their health outcomes. To our knowledge, this is the first study to assess the psychosocial needs and health status of API undocumented young adults. Guided by social capital theory, this qualitative study describes the social context of API undocumented young adults (ages 18-31), including community and government perceptions, and how social relationships influence health...
May 10, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28527340/induction-of-cell-death-by-tospoviral-protein-nss-and-the-motif-critical-for-cell-death-does-not-control-rna-silencing-suppression-activity
#3
Ajeet Singh, Vipin Permar, R K Jain, Suneha Goswami, Ranjeet Ranjan Kumar, Tomas Canto, Peter Palukaitis, Shelly Praveen
Groundnut bud necrosis virus induces necrotic symptoms in different hosts. Previous studies showed reactive oxygen species-mediated programmed cell death (PCD) resulted in necrotic symptoms. Transgenic expression of viral protein NSs mimics viral symptoms. Here, we showed a role for NSs in influencing oxidative burst in the cell, by analyzing H2O2 accumulation, activities of antioxidant enzymes and expression levels of vacuolar processing enzymes, H2O2-responsive microRNA 319a.2 plus its possible target metacaspase-8...
May 17, 2017: Virology
https://www.readbyqxmd.com/read/28527330/home-practice-in-mindfulness-based-cognitive-therapy-and-mindfulness-based-stress-reduction-a-systematic-review-and-meta-analysis-of-participants-mindfulness-practice-and-its-association-with-outcomes
#4
Christine E Parsons, Catherine Crane, Liam J Parsons, Lone Overby Fjorback, Willem Kuyken
Mindfulness-Based Cognitive Therapy (MBCT) and Mindfulness-Based Stress Reduction (MBSR) emphasize the importance of mindfulness practice at home as an integral part of the program. However, the extent to which participants complete their assigned practice is not yet clear, nor is it clear whether this practice is associated with positive outcomes. For this systematic review and meta-analysis, searches were performed using Scopus and PubMed for studies published through to the end of 2015, reporting on formal home practice of mindfulness by MBSR or MBCT participants...
May 10, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28527245/-description-of-mycobacterium-tuberculosis-mutations-conferring-resistance-to-rifampicin-and-isoniazid-detected-by-genotype%C3%A2-mtbdrplus-v-2-in-colombia
#5
Claudia Llerena, Raquel Medina
INTRODUCTION: The GenoType®MTBDRplusV.2 assay is a molecular technique endorsed by the World Health Organization and the Pan American Health Organization that allows for the identification of the Mycobacterium tuberculosis complex and the detection of mutations in the rpoβ gene for rifampicin resistance, and katG and inhA genes for isoniazid resistance. Due to the genetic variability in the circulating strains around the world, the national tuberculosis control programs should assess the performance of these new diagnostic technologies and their use under program conditions as rapid tests...
January 24, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28527235/implementing-the-icf-in-occupational-health-building-a-curriculum-as-an-exemplary-case
#6
C P M de Brouwer, L G P M van Amelsvoort, Y F Heerkens, G A M Widdershoven, I J Kant
BACKGROUND: This paper addresses the need for a paradigm shift from post-diagnosis tertiary care towards maintenance and promotion of health across the lifespan, for healthcare in general and in occupational healthcare specifically. It is based on the assumption that the realization of this paradigm shift may be facilitated by teaching (future) occupational health professionals to use the International Classification of Functioning, Disability and Health (ICF). OBJECTIVE: Describing the development of a an ICF based occupational health curriculum...
May 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28527229/effects-of-interactive-metronome-training-on-upper-extremity-function-adl-and-qol-in-stroke-patients
#7
Ga-Hui Yu, Jae-Shin Lee, Su-Kyoung Kim, Tae-Hyun Cha
BACKGROUND: Rhythm and timing training is stimulation that substitutes for a damaged function controls muscular movement or temporal element, which has positive impacts on the neurological aspect and movement of the brain. OBJECTIVE: This study is to assess the changes caused by rhythm and timing training using an interactive metronome (IM) on upper extremity function, ADL and QOL in stroke patients. METHODS: In order to assess the effects of IM training, a group experiment was conducted on 30 stroke patients...
May 19, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28527225/clinical-feasibility-of-gait-training-with-a%C3%A2-robotic-exoskeleton-wpal-in-an-individual-with-both-incomplete-cervical-and-complete-thoracic-spinal-cord-injury-a%C3%A2-case-study
#8
Shigeo Tanabe, Soichiro Koyama, Eiichi Saitoh, Satoshi Hirano, Kanan Yatsuya, Tetsuya Tsunoda, Masaki Katoh, Takeshi Gotoh, Ayako Furumoto
BACKGROUND: Patients with tetraplegia can achieve independent gait with lateral-type powered exoskeletons; it is unclear whether medial-type powered exoskeletons allow for this. OBJECTIVE: To investigate gait training with a medial-type powered exoskeleton wearable power-assist locomotor (WPAL) in an individual with incomplete cervical (C5) and complete thoracic (T12) spinal cord injury (SCI). METHODS: The 60-session program was investigated retrospectively using medical records...
May 19, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28527224/does-assist-as-needed-upper-limb-robotic-therapy-promote-participation-in-repetitive-activity-based-motor-training-in-sub-acute-stroke-patients-with-severe-paresis
#9
Anne-Gaëlle Grosmaire, Christophe Duret
BACKGROUND: Repetitive, active movement-based training promotes brain plasticity and motor recovery after stroke. Robotic therapy provides highly repetitive therapy that reduces motor impairment. However, the effect of assist-as-needed algorithms on patient participation and movement quality is not known. OBJECTIVE: To analyze patient participation and motor performance during highly repetitive assist-as-needed upper limb robotic therapy in a retrospective study...
May 19, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28527156/the-effect-of-aerobic-or-aerobic-strength-exercise-on-body-composition-and-functional-capacity-in-patients-with-bmi-%C3%A2-35-after-bariatric-surgery-a-randomized-control-trial
#10
Alireza Hassannejad, Alireza Khalaj, Mohammad Ali Mansournia, Mastaneh Rajabian Tabesh, Zahra Alizadeh
BACKGROUND: Although previous studies suggested that bariatric surgery is the most effective and sustainable treatment method for morbid obesity in long term, but without changing in lifestyle, maintaining optimal weight loss is almost impossible. METHODS: Sixty morbid obese patients (BMI ≥ 35) were evaluated before and after 12 weeks of bariatric surgery in order to compare the impact of two different exercise programs on body composition and functional capacity outcomes...
May 19, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28527137/genome-based-identification-of-heterotic-patterns-in-rice
#11
Ulrike Beukert, Zuo Li, Guozheng Liu, Yusheng Zhao, Nadhigade Ramachandra, Vilson Mirdita, Fabiano Pita, Klaus Pillen, Jochen Christoph Reif
BACKGROUND: Hybrid rice breeding facilitates to increase grain yield and yield stability. Long-term success of hybrid breeding depends on the recognition of high-yielding complementary heterotic patterns, which is lacking in crops like rice. RESULT: The main goal of this study was to evaluate the potential and limits to use genomics for establishing heterotic patterns in rice. For this purpose, data of a commercial hybrid rice breeding program targeted to India was analyzed, including 1,960 phenotyped hybrids from three market segments and 262 genotyped parental lines...
December 2017: Rice
https://www.readbyqxmd.com/read/28527078/our-headache-fellowship-a-10-year-history
#12
Paul Rizzoli
There has been a clear trend in American medical education after World War II toward training specialization and subspecialization. After some early specialization efforts by the American Board of Psychiatry and Neurology, further efforts were undertaken by the United Council for Neurologic Subspecialties (UCNS), leading to the introduction of the neurologic subspecialty of Headache Medicine in March, 2005. The training program at our center at the Brigham and Women's Hospital Department of Neurology, Harvard Medical School, in Boston, Massachusetts, was accredited in 2008 and has graduated 14 trainees since its inception...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526974/the-health-equity-scholars-program-innovation-in-the-leaky-pipeline
#13
Carole C Upshur, Diedra M Wrighting, Gonzalo Bacigalupe, Joan Becker, Laura Hayman, Barbara Lewis, Sylvia Mignon, Megan E Rokop, Elizabeth Sweet, Marie Idali Torres, Paul Watanabe, Cedric Woods
Despite attempts to increase enrollment of under-represented minorities (URMs: primarily Black/African American, Hispanic/Latino, and Native American students) in health professional programs, limited progress has been made. Compelling reasons to rectify this situation include equity for URMs, better prepared health professionals when programs are diverse, better quality and access to health care for UMR populations, and the need for diverse talent to tackle difficult questions in health science and health care delivery...
May 19, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28526961/simultaneous-conversion-of-gastric-band-to-sleeve-gastrectomy-is-associated-with-increased-postoperative-complications-an-analysis-of-the-american-college-of-surgeons-national-surgical-quality-improvement-program
#14
Zachary C Dietch, Bruce D Schirmer, Peter T Hallowell
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has gained popularity for the treatment of morbid obesity as gastric banding (BAND) has fallen out of favor. As a result, simultaneous conversion (CONV) of BAND to LSG is commonly performed. We hypothesized that CONV is associated with higher 30-day risk-adjusted serious morbidity. METHODS: Preoperative characteristics and 30-day outcomes from the American College of Surgeons National Surgical Quality Improvement Program Participant Use Files 2010-2014 were selected for patients who underwent LSG...
May 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28526938/reducing-liver-cancer-risk-in-african-born-immigrants-through-culturally-targeted-hepatitis-b-group-education-programs
#15
Kemi Bolutayo, Alexandre Ly van Manh, Noah Cohen, Daouda Ndiaye, Lina Jandorf, Ponni V Perumalswami
Of 900 West African-born immigrants living in New York City who were tested for hepatitis B virus (HBV), over 9% were found to have the infection (Shankar H et al. Clin Infectious Dis 62(S4):S289-s297, 2016). Community targeted group education programs (EP) have been shown to improve immigrant population's health (Bailey E et al. J Natl Med Assoc 92(3):136-42, 2000). Our aim is to enhance HBV screening in at-risk West African immigrants through the development of a group EP as a first critical step to reducing liver cancer risk...
May 19, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28526854/induction-of-senescence-in-primary-glioblastoma-cells-by-serum-and-tgf%C3%AE
#16
Ritesh Kumar, Alexander Gont, Theodore J Perkins, Jennifer E L Hanson, Ian A J Lorimer
Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year. Glioblastomas have a high frequency of mutations in the TERT promoter and CDKN2A locus that are expected to render them resistant to both replicative and oncogene-induced senescence. However, exposure of PriGO8A primary glioblastoma cells to media with 10% serum induced a senescence-like phenotype characterized by increased senescence-associated β galactosidase activity, PML bodies and p21 and morphological changes typical of senescence...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526833/grassland-restoration-reduces-water-yield-in-the-headstream-region-of-yangtze-river
#17
Jia Li, Dan Liu, Tao Wang, Yingnian Li, Shiping Wang, Yuting Yang, Xiaoyi Wang, Hui Guo, Shushi Peng, Jinzhi Ding, Miaogen Shen, Lei Wang
Large-scale ecological restoration programs are considered as one of the key strategies to enhance ecosystem services. The Headstream region of Yangtze River (HYZR), which is claimed to be China's Water Tower but witnessed the rapid grassland deterioration during 1970s-2000, has seen a series of grassland restoration programs since 2000. But few studies have thoroughly estimated the hydrological effect of this recent grassland restoration. Here we show that restoration significantly reduces growing-season water yield coefficient (WYC) from 0...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526824/increasing-generations-in-captivity-is-associated-with-increased-vulnerability-of-tasmanian-devils-to-vehicle-strike-following-release-to-the-wild
#18
Catherine E Grueber, Elizabeth E Reid-Wainscoat, Samantha Fox, Katherine Belov, Debra M Shier, Carolyn J Hogg, David Pemberton
Captive breeding of threatened species, for release to the wild, is critical for conservation. This strategy, however, risks producing captive-raised animals with traits poorly suited to the wild. We describe the first study to characterise accumulated consequences of long-term captive breeding on behaviour, by following the release of Tasmanian devils to the wild. We test the impact of prolonged captive breeding on the probability that captive-raised animals are fatally struck by vehicles. Multiple generations of captive breeding increased the probability that individuals were fatally struck, a pattern that could not be explained by other confounding factors (e...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526704/elder-women-s-perceptions-around-optimal-perinatal-health-a-constructivist-grounded-theory-study-with-an-indigenous-community-in-southern-ontario
#19
Sujane Kandasamy, Meredith Vanstone, Mark Oremus, Trista Hill, Gita Wahi, Julie Wilson, A Darlene Davis, Ruby Jacobs, Rebecca Anglin, Sonia Savitri Anand
BACKGROUND: Women play important roles in translating health knowledge, particularly around pregnancy and birth, in Indigenous societies. We investigated elder Indigenous women's perceptions around optimal perinatal health. METHODS: Using a methodological framework that integrated a constructivist grounded-theory approach with an Indigenous epistemology, we conducted and analyzed in-depth interviews and focus groups with women from the Six Nations community in southern Ontario who self-identified as grandmothers...
May 18, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28526698/improving-response-in-genomic-selection-with-a-population-based-selection-strategy-optimal-population-value-selection
#20
Matthew Goiffon, Aaron Kusmec, Lizhi Wang, Guiping Hu, Patrick Schnable
Genomic selection (GS) identifies individuals for inclusion in breeding programs based on the sum of their estimated marker effects or genomic estimated breeding values (GEBVs). Due to significant correlation between GEBVs and true breeding values, this has resulted in enhanced rates of genetic gain as compared to traditional methods of selection. Three extensions to GS, weighted genomic selection (WGS), optimal haploid value (OHV) selection, and genotype building (GB) selection have been proposed to improve long-term response and to facilitate the efficient development of doubled haploids...
May 19, 2017: Genetics
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