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https://www.readbyqxmd.com/read/29245178/transcriptional-regulation-of-cd4-t-cell-differentiation-in-experimentally-induced-arthritis-and-rheumatoid-arthritis
#1
REVIEW
Yuya Kondo, Masahiro Yokosawa, Shunta Kaneko, Kotona Furuyama, Seiji Segawa, Hiroto Tsuboi, Isao Matsumoto, Takayuki Sumida
Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by infiltration of the joint synovium by activated inflammatory cells. CD4+ T cells form a large proportion of the inflammatory cells invading the synovial tissue, and are involved in the RA pathological process. In general, CD4+ T cells differentiate into various T helper (Th) cell subsets and acquire the functional characterization to respond to specific pathogens, and also mediated some autoimmune disorders such as RA. Because the differentiation of Th cell subsets is determined by the expression of specific transcription factors in response to cytokine environment, these transcription factors is considered to have a role in pathology of RA...
December 15, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29245099/total-bilateral-tmj-reconstruction-for-pain-and-dysfunction-case-report
#2
Carlos Vinícius Ayres Moreira, André Victor Pinto Serra, Larissa Oliveira Ramos Silva, Ana Carolina Fraga Fernandes, Roberto Almeida de Azevedo
INTRODUCTION: Temporomandibular disorders encompass a set of clinical conditions that affect the temporomandibular joint, the masticatory muscles and the associated tissues. Many therapeutic alternatives can be considered, being divided into non-invasive, minimally invasive and invasive interventions. This work aims to report a case of inflammatory joint pain and dysfunction treated with bilateral TMJ full reconstruction with alloplastic prosthesis stock. CASE REPORT: Patient D...
December 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29243678/the-relationship-between-pathological-wear-of-teeth-and-temporomandibular-joint-dysfunction
#3
Egle Mickeviciute, Ausra Baltrusaityte, Gaivile Pileicikiene
OBJECTIVE: Temporomandibular joint dysfunction (TMJD) is quite frequent pathology in population. In scientific literature pathological tooth wear (PTW) is listed among the predisposing factors of it. MATERIAL AND METHODS: During the survey 189 primary patients of dental department in polyclinic of Panevezys city were examined. According to the tooth wear degree 2 groups have been formed: control group (grade 0-1) withouth TMJ dysfunction; and experimental group (grade 2-4) with presumable TMJD...
2017: Stomatologija
https://www.readbyqxmd.com/read/29241750/historical-perspectives-of-the-metabolic-syndrome
#4
Eiji Oda
The metabolic syndrome (MetS) or insulin resistance syndrome is a constellation of obesity-related metabolic derangements predisposing to type 2 diabetes and cardiovascular disease. In 1998, WHO defined the first criteria of MetS. Three years later, the user-friendly National Cholesterol Education Program criteria of MetS were proposed. Different criteria were issued by the International Diabetes Federation in 2005, making abdominal obesity a necessary component. Several international societies, including The International Diabetes Federation, jointly adopted the revised National Cholesterol Education Program criteria as harmonizing criteria of MetS in 2009...
January 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29240586/insights-into-the-pathophysiology-of-hypertrophic-scars-and-keloids-how-do-they-differ
#5
Feras M Ghazawi, Ramin Zargham, Mirko S Gilardino, Denis Sasseville, Fatemeh Jafarian
GENERAL PURPOSE: To provide information about the clinical presentation of hypertrophic scars and keloids based on their varied structural components. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, you should be able to: ABSTRACT: Hypertrophic scars and keloids are firm, raised, erythematous plaques or nodules that manifest when the cicatrix fails to properly heal...
January 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29230905/muscle-control-and-non-specific-chronic-low-back-pain
#6
REVIEW
Marc Russo, Kristiaan Deckers, Sam Eldabe, Kyle Kiesel, Chris Gilligan, John Vieceli, Peter Crosby
OBJECTIVES: Chronic low back pain (CLBP) is the most prevalent of the painful musculoskeletal conditions. CLBP is a heterogeneous condition with many causes and diagnoses, but there are few established therapies with strong evidence of effectiveness (or cost effectiveness). CLBP for which it is not possible to identify any specific cause is often referred to as non-specific chronic LBP (NSCLBP). One type of NSCLBP is continuing and recurrent primarily nociceptive CLBP due to vertebral joint overload subsequent to functional instability of the lumbar spine...
December 12, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29224971/biomechanical-effects-of-a-mandibular-advancement-device-on-the-temporomandibular-joint
#7
David S P Heidsieck, Jan Harm Koolstra, Maurits H T de Ruiter, Aarnoud Hoekema, Jan de Lange
PURPOSE: Mandibular advancement devices are commonly used in the treatment of patients with mild to moderate obstructive sleep apnea (OSA). Designed to maintain the mandible in forced protrusion while being worn, mandibular advancement devices (MADs) are intended to increase the upper airway during sleep, thereby reducing OSA symptoms. Depending on the extent of mandibular protrusion, side effects including temporomandibular joint dysfunction are frequently reported. These are likely to reduce overall treatment success by affecting therapeutic adherence...
November 22, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29223700/unilateral-sagittal-split-ramus-osteotomy-an-alternative-for-some-cases-of-asymmetric-mandibular-prognathism
#8
R Fariña, C Mebus, C Mayer, R Torrealba, E Moreno
The objective of this study was to propose a treatment protocol for patients with lateral prognathism based on the unilateral sagittal split ramus osteotomy (USSRO). This was a prospective study involving 31 patients with lateral prognathism, who required a bilateral sagittal split ramus osteotomy (BSSRO). Two groups were formed using the proposed protocol, with specific inclusion criteria for each group: BSSRO (n=17) and USSRO (n=14). Occlusal parameters (dental midline deviation, overbite, and overjet) were measured preoperatively (T0), at model surgery (T1), 1 month postoperative (T2), and 1year after surgery (T3) and compared...
December 6, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29218229/the-role-of-arthroereisis-of-the-subtalar-joint-for-flatfoot-in-children-and-adults
#9
REVIEW
Alessio Bernasconi, François Lintz, Francesco Sadile
Subtalar arthroereisis has been reported as a minimally-invasive, effective and low-risk procedure in the treatment of flatfoot mainly in children but also in adults.It has been described as a standalone or adjunctive procedure, and is indicated in the treatment of flexible flatfoot, tibialis posterior tendon dysfunction, tarsal coalition and accessory navicular syndrome.Different devices for subtalar arthroereisis are currently used throughout the world associated with soft-tissue and bone procedures, depending on the surgeon rather than on standardised or validated protocols...
November 2017: EFORT open reviews
https://www.readbyqxmd.com/read/29216730/the-influence-of-cranio-cervical-rehabilitation-in-patients-with-myofascial-temporomandibular-pain-disorders
#10
K Halmova, D Holly, P Stanko
OBJECTIVE: The aim of the study was to prove the causality between the craniocervical dysfunction and myofascial pain in the head and neck and to demonstrate the clinical value and usefulness of physiotherapy as one of the therapeutic options for myofascial pain. METHODS: The group of patients diagnosed with myofascial dysfunctional pain syndrome contained 98 patients out of which 79 patients (81 %) were females and 19 patients (19 %) were males. The majority of the patients were aged between 26 and 35 years; the total age range was 14-77 years with the average of 38 years...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29214554/geniposide-suppresses-interleukin-1%C3%AE-induced-inflammation-and-apoptosis-in-rat-chondrocytes-via-the-pi3k-akt-nf-%C3%AE%C2%BAb-signaling-pathway
#11
Tianlong Pan, Xuchao Shi, Huan Chen, Rong Chen, Dengying Wu, Zeng Lin, Jingdong Zhang, Jun Pan
Osteoarthritis (OA) is a chronic degenerative joint disease that is principally characterized by progressive joint dysfunction and cartilage degradation. Inflammation and apoptosis play critical roles in the progression of OA. Geniposide (GPO), one of the principal components of the fruit of Gardenia jasminoides Ellis, has been reported to have anti-inflammatory and other pharmacological effects. In this study, we performed in vitro experiments on rat chondrocytes to examine the therapeutic effects of GPO on OA and investigated its effects in vivo in a rat model of OA induced by medial meniscal tear (MMT)...
December 6, 2017: Inflammation
https://www.readbyqxmd.com/read/29213051/a-robot-aided-visuo-motor-training-that-improves-proprioception-and-spatial-accuracy-of-untrained-movement
#12
Naveen Elangovan, Leonardo Cappello, Lorenzo Masia, Joshua Aman, Jürgen Konczak
Proprioceptive function can become enhanced during motor learning. Yet, we have incomplete knowledge to what extent proprioceptive function is trainable and how a training that enhances proprioception may influence performance in untrained motor skills. To address this knowledge gap, healthy young adults (N = 14) trained in a visuomotor task that required learners to make increasingly accurate wrist movements. Using a robotic exoskeleton coupled with a virtual visual environment, participants tilted a virtual table through continuous wrist flexion/extension movements with the goal to position a rolling ball on table into a target...
December 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29206793/diagnosis-and-management-of-sacroiliac-joint-dysfunction
#13
David C Ou-Yang, Philip J York, Christopher J Kleck, Vikas V Patel
No abstract text is available yet for this article.
December 6, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29199431/six-month-clinical-course-and-factors-associated-with-non-improvement-in-migraine-and-non-migraine-headaches
#14
Maria-Eliza R Aguila, Trudy Rebbeck, Alun Pope, Karl Ng, Andrew M Leaver
Background Evidence on the medium-term clinical course of recurrent headaches is scarce. This study explored the six-month course and factors associated with non-improvement in migraine compared with tension-type headache and cervicogenic headache. Methods In this longitudinal cohort study, the six-month course of headaches was prospectively examined in participants (n = 37 with migraine; n = 42 with tension-type or cervicogenic headache). Participants underwent physical examination for cervical musculoskeletal impairments at baseline...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29198045/physical-and-mental-health-status-and-their-correlations-among-older-wheelchair-users-with-dementia-in-long-term-care-facilities
#15
Chu-Lin Chang, Kuei-Min Chen
PURPOSE: To investigate the physical health (daily functioning and functional fitness) and mental health (depression and behavioral dysfunction) of older wheelchair users with dementia in long-term care facilities, examine the correlations between physical and mental health, and identify the independent variables of their daily functioning. METHODS: A descriptive correlational method was adopted, which was conducted in six long-term care facilities in three cities, south Taiwan...
December 2, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29191288/spinal-manipulative-therapy-and-sports-performance-enhancement-a-systematic-review
#16
REVIEW
Marcelo B Botelho, Bruno A P Alvarenga, Nícolly Molina, Marcos Ribas, Abrahão F Baptista
OBJECTIVE: The purpose of this study was to review the literature regarding the relationship between spinal manipulative therapy (SMT) and sports performance. METHODS: PubMed and Embase databases were searched for original studies published up to July 2016. Inclusion criteria were if SMT has been applied to athletes and if any sports performance-related outcome was measured. RESULTS: Of the 581 potential studies, 7 clinical trials were selected...
September 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29188646/-application-of-temporomandibular-joint-dics-reduction-in-the-operation-of-condylar-sagittal-fracture
#17
Zeng Wenli, Zhou Wuchao, Zhang Jingkun, Shao Yisen, Xi Weihong
OBJECTIVE: To explore the selection of temporomandibular joint (TMJ) disc reduction and fixation methods in condylar sagittal fracture surgery. METHODS: A total of 36 patients with condylar fractures were chosen. The follow-up period was more 6 months. All 36 cases of condylar sagittal fracture were fixed with long screw. In the operation, the displaced joint disc was repositioned and fixed. The fixed method included direct suture (22 cases) and anchorage (14 cases)...
October 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29184713/posterior-atlantoaxial-fusion-using-a-c2-transverse-foramen-penetrating-screw-a-technical-note
#18
Yasuhiro Takeshima, Hideki Shigematsu, Kengo Konishi, Ichiro Nakagawa, Yasushi Motoyama, Hiroyuki Nakase
Background: Although recent development of screw instrumentation techniques for rigid fixation of the atlantoaxial joint has increased surgical options, patients in whom screws of any type cannot be safely placed are sometimes encountered. We present a unique surgical technique for C1-2 transarticular screw placement utilizing a novel trajectory. Methods: A 35-year-old male with a history of Down's syndrome and cognitive dysfunction with hyperkinesis spontaneously developed rapid onset of tetraparesis and gait disturbance...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29175087/iso-risk-air-no-decompression-limits-after-scoring-marginal-decompression-sickness-cases-as-non-events
#19
F Gregory Murphy, Ashleigh J Swingler, Wayne A Gerth, Laurens E Howle
Decompression sickness (DCS) in humans is associated with reductions in ambient pressure that occur during diving, aviation, or certain manned spaceflight operations. Its signs and symptoms can include, but are not limited to, joint pain, radiating abdominal pain, paresthesia, dyspnea, general malaise, cognitive dysfunction, cardiopulmonary dysfunction, and death. Probabilistic models of DCS allow the probability of DCS incidence and time of occurrence during or after a given hyperbaric or hypobaric exposure to be predicted based on how the gas contents or gas bubble volumes vary in hypothetical tissue compartments during the exposure...
November 15, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29170690/correlation-between-the-functional-movement-screen-and-hip-mobility-in-ncaa-division-ii-athletes
#20
Matthew T Jenkins, Robert Gustitus, Mike Iosia, Taz Kicklighter, Yuichi Sasaki
The Functional Movement Screen (FMS) is a series of seven exercises designed to assess athletes prior to competitive training to determine dysfunctional movement patterns. The exercises include the deep squat (DS), hurdle step (HS), inline lunge (IL), shoulder mobility (SM), active straight leg raise (ASL), pushup (PU), and rotary stability (RS), all of which comprise the composite score (FMS CS). The purpose of this study was to determine correlations between the FMS screens and hip mobility. The specific hip range-of-motion exercises used were bilateral internal/external rotation (IRR, IRL ERL, ERR), and flexion/extension (FL, FR, ER, EL)...
2017: International Journal of Exercise Science
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