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https://www.readbyqxmd.com/read/29344989/salmon-calcitonin-ameliorates-migraine-pain-through-modulation-of-cgrp-release-and-dural-mast-cell-degranulation-in-rats
#1
Erkan Kilinc, Yasar Dagistan, Aysel Kukner, Bayram Yilmaz, Sami Agus, Gizem Soyler, Fatma Tore
The exact mechanism of migraine pathophysiology still remains unclear due to the complex nature of migraine pain. Salmon calcitonin (SC) exhibits antinociceptive effects in the treatment of various pain conditions. In this study, we explored the mechanisms underlying the analgesic effect of salmon calcitonin on migrane pain using glyceryltrinitrate(GTN)-induced model of migraine and ex-vivo meningeal preparations in rats. Rats were administered intraperitoneally saline, GTN(10mg/kg), vehicle, saline+GTN, SC(50μg/kg)+GTN, and SC alone...
January 18, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29335689/psoriasis-a-review-of-systemic-comorbidities-and-dental-management-considerations
#2
John K Brooks
OBJECTIVE: There is a growing body of evidence to substantiate that cutaneous psoriasis is associated with an increased risk for a multitude of systemic disorders. Although there is an extensive array of medical publications regarding psoriasis, the dental literature has almost exclusively been focused on erythema migrans and occasionally, with oral psoriatic mucositis, chronic periodontitis, and psoriatic arthritis of the temporomandibular joint. This report will review the diversity of systemic comorbidities, namely cardiovascular, neurologic, renal, liver, gastrointestinal, pulmonary, endocrine, ocular, arthritic (including temporomandibular joint), nail, cutaneous, and psychologic (including suicide) disorders; neoplasia; infection; dyslipidemia; vitamin D deficiency; substance abuse; higher mortality; and oral mucosal involvement...
January 15, 2018: Quintessence International
https://www.readbyqxmd.com/read/29330280/cutaneous-larva-migrans-with-pulmonary-involvement
#3
Douglas Maslin, Marc Wallace
No abstract text is available yet for this article.
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29299379/headache-in-the-first-manifestation-of-multiple-sclerosis%C3%A2-%C3%A2-prospective-multicenter-study
#4
Marcel Gebhardt, Peter Kropp, Tim P Jürgens, Frank Hoffmann, Uwe K Zettl
Objectives: Multiple sclerosis (MS) is the most frequent immune-mediated inflammation of the central nervous system that can lead to early disability. Headaches have not been considered as MS-related symptoms initially, whereas higher prevalence rates were reported since 2000. Postmortem histological analyses of MS patients' brains revealed lymphoid follicle-like structures in the cerebral meninges which suggest a possible pathophysiological explanation for the high headache prevalence in MS...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29275956/lyme-carditis-early-occurrence-and-prolonged-recovery
#5
Jianwei Fu Md, Luna Bhatta
Lyme carditis is an uncommon manifestation of early disseminated Lyme disease. This case illustrates a 66-year-old male with complaints of fatigue, myalgias, and fever after a tick bite 3days earlier. A large erythema migrans was found on the chest wall. Initial electrocardiogram showed sinus rhythm with second degree 2:1 atrioventricular (AV) block, which progressed to intermittent complete AV block rapidly. He was treated with intravenous ceftriaxone. Over the course of 2-weeks of antibiotic therapy, the intermittent high-grade AV block improved slowly and progressively...
December 14, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29260744/-clinical-presentation-of-ixodes-tick-borne-borreliosis-caused-by-borrelia-miyamotoi-in-the-context-of-an-immune-response-to-the-pathogen
#6
A E Platonov, M G Toporkova, N M Kolyasnikova, O A Stukolova, A S Dolgova, A V Brodovikova, N A Makhneva, L S Karan, J Koetsveld, G A Shipulin, V V Maleev
Ixodes tick-borne borreliosis caused by Borrelia miyamotoi (ITBB-BM) is a previously unknown infectious disease discovered in Russia. AIM: The present study continues the investigation of the clinical features of ITBB-BM in the context of an immune system-pathogen interaction. SUBJECTS AND METHODS: The study enrolled 117 patients with ITBB-BM and a comparison group of 71 patients with Lyme disease (LD) that is ITBB with erythema migrans. All the patients were treated at the New Hospital, Yekateringburg...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29241639/facial-cutaneous-larva-migrans-acquired-in-spain
#7
C Durán-Vian, I Vilanova-Udaniz, B Castro-Gutierrez, M A González-López
No abstract text is available yet for this article.
December 11, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29238878/offal-dumping-sites-influence-the-relative-abundance-and-roosting-site-selection-of-black-kites-milvus-migrans-govinda-in-urban-landscape-a-study-from-kolkata-metropolis-india
#8
Subhendu Mazumdar, Dipankar Ghose, Goutam Kumar Saha
Although Black Kites (Milvus migrans govinda) serve as major scavenging raptor in most of the urban areas, scientific studies on this important ecosystem service provider are almost non-existent in Indian context. The present study was carried out in a metropolis in eastern India to find out the factors influencing relative abundance and roosting site selection of Black Kites. Separate generalized linear models (GLMs) were performed considering encounter rate and roosting Black Kite abundance as response variables...
December 14, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29223937/echinococcosis-and-other-parasitic-infections-in-domestic-dogs-from-urban-areas-of-an-argentinean-patagonian-city
#9
Verónica Flores, Gustavo Viozzi, Gilda Garibotti, Daniela Zacharias, María Florencia Debiaggi, Surpik Kabaradjian
In urban populations of South America, dogs with free access to public areas represent a public health concern. The primary consequence of roaming dogs on human health is the transmission of infectious and parasitic diseases mainly through feces contamination. The main diseases likely to be transmitted are hydatidosis or echinococcosis, larva migrans, and giardiasis. In Argentina, hydatidosis ranks among the most prevalent zoonosis. Although it is considered a rural disease, the circulation of this parasite in urban areas has been documented...
2017: Medicina
https://www.readbyqxmd.com/read/29213175/cutaneous-larva-migrans-in-a-child
#10
S N Prashanth, K Jagadish Kumar, M G Anil Kumar
No abstract text is available yet for this article.
2017: Sudanese Journal of Paediatrics
https://www.readbyqxmd.com/read/29208342/pediatric-stroke-related-to-lyme-neuroborreliosis-data-from-the-swiss-neuropaediatric-stroke-registry-and-literature-review
#11
O Monteventi, M Steinlin, M Regényi, E Roulet-Perez, P Weber, J Fluss
BACKGROUND: Cerebrovascular complications of Lyme neuroborreliosis (LNB) are poorly documented in the paediatric population. METHODS: We performed a retrospective analysis from prospectively registered cases of acute ischemic stroke (AIS) from the Swiss NeuroPaediatric Stroke Registry (SNPSR) from 2000 to 2015. Only cases with serologically confirmed LNB were included. In addition, a literature review on paediatric stroke cases secondary to Lyme neuroborreliosis in the same time frame was performed...
November 24, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29205927/areolar-lymphocytoma-in-a-child-a-rare-cutaneous-presentation-of-borreliosis
#12
Chikara Ogimi, Claudia Crowell, Markus D Boos
Lyme disease is a common tick-borne infection caused by Borrelia burgdorferi in the United States, where infection is most prevalent in the northeastern and mid-Atlantic states. Although classically associated with erythema migrans, Lyme disease caused by Borrelia species found in Europe may also present with other cutaneous findings. Here we report the case of a girl who was clinically diagnosed with Lyme disease based on her history of recent travel and the appearance of an areolar lymphocytoma; this was confirmed by testing...
December 4, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29175973/accuracy-of-clinician-suspicion-of-lyme-disease-in-the-emergency-department
#13
MULTICENTER STUDY
Lise E Nigrovic, Jonathan E Bennett, Fran Balamuth, Michael N Levas, Rachel L Chenard, Alexandra B Maulden, Aris C Garro
BACKGROUND: To make initial management decisions, clinicians must estimate the probability of Lyme disease before diagnostic test results are available. Our objective was to examine the accuracy of clinician suspicion for Lyme disease in children undergoing evaluation for Lyme disease. METHODS: We assembled a prospective cohort of children aged 1 to 21 years who were evaluated for Lyme disease at 1 of the 5 participating emergency departments. Treating physicians were asked to estimate the probability of Lyme disease (on a 10-point scale)...
December 2017: Pediatrics
https://www.readbyqxmd.com/read/29151040/meningoencephalitis-in-a-royal-marine-after-skinning-reindeer-in-norway
#14
Christopher A Pollard, D S Burns, B Ho, A McD Johnston
Meningoencephalitis presenting in service personnel overseas may present a diagnostic challenge due to the broad range of potential differential diagnosis as well as the requirement for rapid assessment and treatment. A 25-year-old Royal Marine was evacuated to the Royal Centre for Defence Medicine in Birmingham, UK, with a history of rash consistent with erythema chronicum migrans, a seizure, and lymphocytic pleocytosis after skinning reindeer in Norway. Neuroborreliosis was suspected and empirical antibiotics were administered...
November 18, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29120995/surveillance-for-lyme-disease-united-states-2008-2015
#15
Amy M Schwartz, Alison F Hinckley, Paul S Mead, Sarah A Hook, Kiersten J Kugeler
PROBLEM/CONDITION: Lyme disease is the most commonly reported vectorborne disease in the United States but is geographically focal. The majority of Lyme disease cases occur in the Northeast, mid-Atlantic, and upper Midwest regions. Lyme disease can cause varied clinical manifestations, including erythema migrans, arthritis, facial palsy, and carditis. Lyme disease occurs most commonly among children and older adults, with a slight predominance among males. REPORTING PERIOD: 2008-2015...
November 10, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29120339/hepatic-visceral-larva-migrans-causing-hepatic-venous-thrombosis-and-prolonged-fever
#16
Jaswinder Kaur, Anand Gupta, Nishant Wadhwa
BACKGROUND: Visceral larva migrans may present with systemic symptoms such as fever, hepatomegaly, pneumonitis or ocular symptoms. CASE CHARACTERISTICS: A 7-year-old girl with fever, pain abdomen and persistent eosinophilia. Imaging and histopathology were suggestive of visceral larva migrans. MESSAGE: The diagnosis of visceral larva migrans is often delayed since similar symptoms of fever, hepatomegaly and peripheral eosinophilia occur in more common and identifiable tropical parasitic and non-parasitic diseases...
October 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29099929/transcriptome-assessment-of-erythema-migrans-skin-lesions-in-patients-with-early-lyme-disease-reveals-predominant-interferon-signaling
#17
Adriana Marques, Ira Schwartz, Gary P Wormser, Yanmei Wang, Ronald L Hornung, Cumhur Y Demirkale, Peter J Munson, Siu-Ping Turk, Carla Williams, Chyi-Chia Richard Lee, Jun Yang, Mary M Petzke
Background: The most common clinical manifestation of early Lyme disease is the erythema migrans (EM) skin lesion that develops at the tick bite site typically between 7 and 14 days following infection with Borreliella burgdorferi. The host-pathogen interactions that occur in the skin may have a critical role in determining outcome of infection. Methods: Gene arrays were utilized to characterize the global transcriptional alterations in skin biopsy samples of EM lesions from untreated adult patients with Lyme disease in comparison to controls...
November 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29090059/successful-treatment-of-corneal-larva-migrans-by-nd-yag-laser-photodisruption
#18
Jisha Kamalakshy, Krishna Babu, Padmasree Kamala Madhavan, Seshadrinathan Subrahmaniam
No abstract text is available yet for this article.
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29080105/a-modified-method-for-molecular-identification-of-baylisascaris-transfuga-in-european-brown-bears-ursus-arctos
#19
Jakub Gawor, Jan Gawor, Robert Gromadka, Tomasz Zwijacz-Kozica, Filip Zięba
Baylisascaris transfuga is a roundworm that has been reported worldwide in most bear species. In mammals and possibly humans, the larvae of B. transfuga can migrate in the tissues of aberrant hosts with larva migrans syndrome. The current study was performed to identify B. transfuga in faecal samples from free-ranging brown bears in the Tatra Mountains National Park in southern Poland. A commercial kit was used to extract genomic DNA directly from faecal samples. Additionally, a Chelex resin-based technique was successfully implemented to prepare a PCR template from eggs retrieved by flotation...
October 27, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29063358/geographic-distribution-and-incidence-of-lyme-borreliosis-in-the-west-of-ireland
#20
A Vellinga, H Kilkelly, J Cullinan, B Hanahoe, M Cormican
BACKGROUND: Lyme borreliosis is caused by Borrelia burgdorferi and is the most common tick-transmitted infection in temperate regions. Infection often presents with erythema migrans and/or other clinical features in early infection. METHODS: Blood samples are submitted for testing for antibodies to Borrelia burgdorferi by enzyme immunoassay and positive samples are confirmed by a reference laboratory by IgG and IgM line immune assay. A retrospective extraction of all laboratory requests and results for Lyme borreliosis from 2011 to 2014 was performed...
October 23, 2017: Irish Journal of Medical Science
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